---
_id: '3529'
abstract:
- lang: eng
text: Parallel recording of neuronal activity in the behaving animal is a prerequisite
for our understanding of neuronal representation and storage of information. Here
we describe the development of micro-machined silicon microelectrode arrays for
unit and local field recordings. The two-dimensional probes with 96 or 64 recording
sites provided high-density recording of unit and field activity with minimal
tissue displacement or damage. The on-chip active circuit eliminated movement
and other artifacts and greatly reduced the weight of the headgear. The precise
geometry of the recording tips allowed for the estimation of the spatial location
of the recorded neurons and for high-resolution estimation of extracellular current
source density. Action potentials could be simultaneously recorded from the soma
and dendrites of the same neurons. Silicon technology is a promising approach
for high-density, high-resolution sampling of neuronal activity in both basic
research and prosthetic devices.
author:
- first_name: Jozsef L
full_name: Jozsef Csicsvari
id: 3FA14672-F248-11E8-B48F-1D18A9856A87
last_name: Csicsvari
orcid: 0000-0002-5193-4036
- first_name: Darrell
full_name: Henze, Darrell A
last_name: Henze
- first_name: Brian
full_name: Jamieson, Brian G
last_name: Jamieson
- first_name: Kenneth
full_name: Harris, Kenneth D
last_name: Harris
- first_name: Anton
full_name: Sirota, Anton M
last_name: Sirota
- first_name: Peter
full_name: Bartho, Peter
last_name: Bartho
- first_name: Kensall
full_name: Wise, Kensall D
last_name: Wise
- first_name: György
full_name: Buzsáki, György
last_name: Buzsáki
citation:
ama: Csicsvari JL, Henze D, Jamieson B, et al. Massively parallel recording of unit
and local field potentials with silicon-based electrodes. Journal of Neurophysiology.
2003;90(2):1314-1323. doi:10.1152/jn.00116.2003
apa: Csicsvari, J. L., Henze, D., Jamieson, B., Harris, K., Sirota, A., Bartho,
P., … Buzsáki, G. (2003). Massively parallel recording of unit and local field
potentials with silicon-based electrodes. Journal of Neurophysiology. American
Physiological Society. https://doi.org/10.1152/jn.00116.2003
chicago: Csicsvari, Jozsef L, Darrell Henze, Brian Jamieson, Kenneth Harris, Anton
Sirota, Peter Bartho, Kensall Wise, and György Buzsáki. “Massively Parallel Recording
of Unit and Local Field Potentials with Silicon-Based Electrodes.” Journal
of Neurophysiology. American Physiological Society, 2003. https://doi.org/10.1152/jn.00116.2003.
ieee: J. L. Csicsvari et al., “Massively parallel recording of unit and local
field potentials with silicon-based electrodes,” Journal of Neurophysiology,
vol. 90, no. 2. American Physiological Society, pp. 1314–1323, 2003.
ista: Csicsvari JL, Henze D, Jamieson B, Harris K, Sirota A, Bartho P, Wise K, Buzsáki
G. 2003. Massively parallel recording of unit and local field potentials with
silicon-based electrodes. Journal of Neurophysiology. 90(2), 1314–1323.
mla: Csicsvari, Jozsef L., et al. “Massively Parallel Recording of Unit and Local
Field Potentials with Silicon-Based Electrodes.” Journal of Neurophysiology,
vol. 90, no. 2, American Physiological Society, 2003, pp. 1314–23, doi:10.1152/jn.00116.2003.
short: J.L. Csicsvari, D. Henze, B. Jamieson, K. Harris, A. Sirota, P. Bartho, K.
Wise, G. Buzsáki, Journal of Neurophysiology 90 (2003) 1314–1323.
date_created: 2018-12-11T12:03:48Z
date_published: 2003-08-01T00:00:00Z
date_updated: 2021-01-12T07:44:05Z
day: '01'
doi: 10.1152/jn.00116.2003
extern: 1
intvolume: ' 90'
issue: '2'
month: '08'
page: 1314 - 1323
publication: Journal of Neurophysiology
publication_status: published
publisher: American Physiological Society
publist_id: '2856'
quality_controlled: 0
status: public
title: Massively parallel recording of unit and local field potentials with silicon-based
electrodes
type: journal_article
volume: 90
year: '2003'
...
---
_id: '3528'
abstract:
- lang: eng
text: Gamma frequency oscillations (30-100 Hz) have been suggested to underlie various
cognitive and motor functions. Here, we examine the generation of gamma oscillation
currents in the hippocampus, using two-dimensional, 96-site silicon probes. Two
gamma generators were identified, one in the dentate gyrus and another in the
CA3-CA1 regions. The coupling strength between the two oscillators varied during
both theta and nontheta states. Both pyramidal cells and interneurons were phase-locked
to gamma waves. Anatomical connectivity, rather than physical distance, determined
the coupling strength of the oscillating neurons. CA3 pyramidal neurons discharged
CA3 and CA1 interneurons at latencies indicative of monosynaptic connections.
Intrahippocampal gamma oscillation emerges in the CA3 recurrent system, which
entrains the CA1 region via its interneurons.
author:
- first_name: Jozsef L
full_name: Jozsef Csicsvari
id: 3FA14672-F248-11E8-B48F-1D18A9856A87
last_name: Csicsvari
orcid: 0000-0002-5193-4036
- first_name: Brian
full_name: Jamieson, Brian G
last_name: Jamieson
- first_name: Kensall
full_name: Wise, Kensall D
last_name: Wise
- first_name: György
full_name: Buzsáki, György
last_name: Buzsáki
citation:
ama: Csicsvari JL, Jamieson B, Wise K, Buzsáki G. Mechanisms of gamma oscillations
in the hippocampus of the behaving rat. Neuron. 2003;37(2):311-322. doi:10.1016/S0896-6273(02)01169-8
apa: Csicsvari, J. L., Jamieson, B., Wise, K., & Buzsáki, G. (2003). Mechanisms
of gamma oscillations in the hippocampus of the behaving rat. Neuron. Elsevier.
https://doi.org/10.1016/S0896-6273(02)01169-8
chicago: Csicsvari, Jozsef L, Brian Jamieson, Kensall Wise, and György Buzsáki.
“Mechanisms of Gamma Oscillations in the Hippocampus of the Behaving Rat.” Neuron.
Elsevier, 2003. https://doi.org/10.1016/S0896-6273(02)01169-8.
ieee: J. L. Csicsvari, B. Jamieson, K. Wise, and G. Buzsáki, “Mechanisms of gamma
oscillations in the hippocampus of the behaving rat,” Neuron, vol. 37,
no. 2. Elsevier, pp. 311–322, 2003.
ista: Csicsvari JL, Jamieson B, Wise K, Buzsáki G. 2003. Mechanisms of gamma oscillations
in the hippocampus of the behaving rat. Neuron. 37(2), 311–322.
mla: Csicsvari, Jozsef L., et al. “Mechanisms of Gamma Oscillations in the Hippocampus
of the Behaving Rat.” Neuron, vol. 37, no. 2, Elsevier, 2003, pp. 311–22,
doi:10.1016/S0896-6273(02)01169-8.
short: J.L. Csicsvari, B. Jamieson, K. Wise, G. Buzsáki, Neuron 37 (2003) 311–322.
date_created: 2018-12-11T12:03:48Z
date_published: 2003-01-01T00:00:00Z
date_updated: 2021-01-12T07:44:05Z
day: '01'
doi: 10.1016/S0896-6273(02)01169-8
extern: 1
intvolume: ' 37'
issue: '2'
month: '01'
page: 311 - 322
publication: Neuron
publication_status: published
publisher: Elsevier
publist_id: '2857'
quality_controlled: 0
status: public
title: Mechanisms of gamma oscillations in the hippocampus of the behaving rat
type: journal_article
volume: 37
year: '2003'
...
---
_id: '3543'
abstract:
- lang: eng
text: Both neocortical and hippocampal networks organize the firing patterns of
their neurons by prominent oscillations during sleep, but the functional role
of these rhythms is not well understood. Here, we show a robust correlation of
neuronal discharges between the somatosensory cortex and hippocampus on both slow
and fine time scales in the mouse and rat. Neuronal bursts in deep cortical layers,
associated with sleep spindles and delta waves/slow rhythm, effectively triggered
hippocampal discharges related to fast (ripple) oscillations. We hypothesize that
oscillation-mediated temporal links coordinate specific information transfer between
neocortical and hippocampal cell assemblies. Such a neocortical-hippocampal interplay
may be important for memory consolidation.
author:
- first_name: Anton
full_name: Sirota, Anton M
last_name: Sirota
- first_name: Jozsef L
full_name: Jozsef Csicsvari
id: 3FA14672-F248-11E8-B48F-1D18A9856A87
last_name: Csicsvari
orcid: 0000-0002-5193-4036
- first_name: Derek
full_name: Buhl, Derek L
last_name: Buhl
- first_name: György
full_name: Buzsáki, György
last_name: Buzsáki
citation:
ama: Sirota A, Csicsvari JL, Buhl D, Buzsáki G. Communication between neocortex
and hippocampus during sleep in rodents. PNAS. 2003;100(4):2065-2069. doi:10.1073/pnas.0437938100
apa: Sirota, A., Csicsvari, J. L., Buhl, D., & Buzsáki, G. (2003). Communication
between neocortex and hippocampus during sleep in rodents. PNAS. National
Academy of Sciences. https://doi.org/10.1073/pnas.0437938100
chicago: Sirota, Anton, Jozsef L Csicsvari, Derek Buhl, and György Buzsáki. “Communication
between Neocortex and Hippocampus during Sleep in Rodents.” PNAS. National
Academy of Sciences, 2003. https://doi.org/10.1073/pnas.0437938100.
ieee: A. Sirota, J. L. Csicsvari, D. Buhl, and G. Buzsáki, “Communication between
neocortex and hippocampus during sleep in rodents,” PNAS, vol. 100, no.
4. National Academy of Sciences, pp. 2065–2069, 2003.
ista: Sirota A, Csicsvari JL, Buhl D, Buzsáki G. 2003. Communication between neocortex
and hippocampus during sleep in rodents. PNAS. 100(4), 2065–2069.
mla: Sirota, Anton, et al. “Communication between Neocortex and Hippocampus during
Sleep in Rodents.” PNAS, vol. 100, no. 4, National Academy of Sciences,
2003, pp. 2065–69, doi:10.1073/pnas.0437938100.
short: A. Sirota, J.L. Csicsvari, D. Buhl, G. Buzsáki, PNAS 100 (2003) 2065–2069.
date_created: 2018-12-11T12:03:53Z
date_published: 2003-02-18T00:00:00Z
date_updated: 2021-01-12T07:44:12Z
day: '18'
doi: 10.1073/pnas.0437938100
extern: 1
intvolume: ' 100'
issue: '4'
month: '02'
page: 2065 - 2069
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '2841'
quality_controlled: 0
status: public
title: Communication between neocortex and hippocampus during sleep in rodents
type: journal_article
volume: 100
year: '2003'
...
---
_id: '3593'
abstract:
- lang: eng
text: Temporal logics such as Computation Tree Logic (CTL) and Linear Temporal Logic
(LTL) have become popular for specifying temporal properties over a wide variety
of planning and verification problems. In this paper we work towards building
a generalized framework for automated reasoning based on temporal logics. We present
a powerful extension of CTL with first-order quantification over the set of reachable
states for reasoning about extremal properties of weighted labeled transition
systems in general. The proposed logic, which we call Weighted Quantified Computation
Tree Logic (WQCTL), captures the essential elements common to the domain of planning
and verification problems and can thereby be used as an effective specification
language in both domains. We show that in spite of the rich, expressive power
of the logic, we are able to evaluate WQCTL formulas in time polynomial in the
size of the state space times the length of the formula. Wepresent experimental
results on the WQCTL verifier.
author:
- first_name: Krishnendu
full_name: Krishnendu Chatterjee
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Pallab
full_name: Dasgupta, Pallab
last_name: Dasgupta
- first_name: Partha
full_name: Chakrabarti, Partha P
last_name: Chakrabarti
citation:
ama: Chatterjee K, Dasgupta P, Chakrabarti P. A branching time temporal framework
for quantitative reasoning. Journal of Automated Reasoning. 2003;30(2):205-232.
doi:10.1023/A:1023217515688
apa: Chatterjee, K., Dasgupta, P., & Chakrabarti, P. (2003). A branching time
temporal framework for quantitative reasoning. Journal of Automated Reasoning.
Springer. https://doi.org/10.1023/A:1023217515688
chicago: Chatterjee, Krishnendu, Pallab Dasgupta, and Partha Chakrabarti. “A Branching
Time Temporal Framework for Quantitative Reasoning.” Journal of Automated Reasoning.
Springer, 2003. https://doi.org/10.1023/A:1023217515688.
ieee: K. Chatterjee, P. Dasgupta, and P. Chakrabarti, “A branching time temporal
framework for quantitative reasoning,” Journal of Automated Reasoning,
vol. 30, no. 2. Springer, pp. 205–232, 2003.
ista: Chatterjee K, Dasgupta P, Chakrabarti P. 2003. A branching time temporal framework
for quantitative reasoning. Journal of Automated Reasoning. 30(2), 205–232.
mla: Chatterjee, Krishnendu, et al. “A Branching Time Temporal Framework for Quantitative
Reasoning.” Journal of Automated Reasoning, vol. 30, no. 2, Springer, 2003,
pp. 205–32, doi:10.1023/A:1023217515688.
short: K. Chatterjee, P. Dasgupta, P. Chakrabarti, Journal of Automated Reasoning
30 (2003) 205–232.
date_created: 2018-12-11T12:04:08Z
date_published: 2003-02-01T00:00:00Z
date_updated: 2021-01-12T07:44:31Z
day: '01'
doi: 10.1023/A:1023217515688
extern: 1
intvolume: ' 30'
issue: '2'
month: '02'
page: 205 - 232
publication: Journal of Automated Reasoning
publication_status: published
publisher: Springer
publist_id: '2790'
quality_controlled: 0
status: public
title: A branching time temporal framework for quantitative reasoning
type: journal_article
volume: 30
year: '2003'
...
---
_id: '3678'
author:
- first_name: Christoph
full_name: Christoph Lampert
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
citation:
ama: Lampert C. The Neumann operator in strictly pseudoconvex domains with weighted
Bergman metric . Bonner Mathematische Schriften. 2003;356:1-165.
apa: Lampert, C. (2003). The Neumann operator in strictly pseudoconvex domains
with weighted Bergman metric . Bonner Mathematische Schriften. Universität
Bonn, Fachbibliothek Mathematik.
chicago: Lampert, Christoph. “The Neumann Operator in Strictly Pseudoconvex Domains
with Weighted Bergman Metric .” Bonner Mathematische Schriften. Universität
Bonn, Fachbibliothek Mathematik, 2003.
ieee: C. Lampert, “The Neumann operator in strictly pseudoconvex domains with weighted
Bergman metric ,” Universität Bonn, Fachbibliothek Mathematik, 2003.
ista: Lampert C. 2003. The Neumann operator in strictly pseudoconvex domains with
weighted Bergman metric . Universität Bonn, Fachbibliothek Mathematik.
mla: Lampert, Christoph. “The Neumann Operator in Strictly Pseudoconvex Domains
with Weighted Bergman Metric .” Bonner Mathematische Schriften, vol. 356,
Universität Bonn, Fachbibliothek Mathematik, 2003, pp. 1–165.
short: C. Lampert, The Neumann Operator in Strictly Pseudoconvex Domains with Weighted
Bergman Metric , Universität Bonn, Fachbibliothek Mathematik, 2003.
date_created: 2018-12-11T12:04:34Z
date_published: 2003-03-31T00:00:00Z
date_updated: 2021-01-12T07:45:05Z
day: '31'
extern: 1
intvolume: ' 356'
main_file_link:
- open_access: '0'
url: http://pub.ist.ac.at/~chl/papers/lampert-phd2003.pdf
month: '03'
page: 1 - 165
publication: Bonner Mathematische Schriften
publication_status: published
publisher: Universität Bonn, Fachbibliothek Mathematik
publist_id: '2704'
quality_controlled: 0
status: public
title: 'The Neumann operator in strictly pseudoconvex domains with weighted Bergman
metric '
type: dissertation
volume: 356
year: '2003'
...
---
_id: '3725'
abstract:
- lang: eng
text: The combination of high-resolution atomic force microscopy (AFM) imaging and
single-molecule force-spectroscopy was employed to unfold single bacteriorhodopsins
(BR) from native purple membrane patches at various physiologically relevant temperatures.
The unfolding spectra reveal detailed insight into the stability of individual
structural elements of BR against mechanical unfolding. Intermittent states in
the unfolding process are associated with the stepwise unfolding of alpha-helices,
whereas other states are associated with the unfolding of polypeptide loops connecting
the alpha-helices. It was found that the unfolding forces of the secondary structures
considerably decreased upon increasing the temperature from 8 to 52°C. Associated
with this effect, the probability of individual unfolding pathways of BR was significantly
influenced by the temperature. At lower temperatures, transmembrane alpha-helices
and extracellular polypeptide loops exhibited sufficient stability to individually
establish potential barriers against unfolding, whereas they predominantly unfolded
collectively at elevated temperatures. This suggests that increasing the temperature
decreases the mechanical stability of secondary structural elements and changes
molecular interactions between secondary structures, thereby forcing them to act
as grouped structures.
author:
- first_name: Harald L
full_name: Harald Janovjak
id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
last_name: Janovjak
orcid: 0000-0002-8023-9315
- first_name: Max
full_name: Kessler, Max
last_name: Kessler
- first_name: Dieter
full_name: Oesterhelt, Dieter
last_name: Oesterhelt
- first_name: Hermann
full_name: Gaub, Hermann
last_name: Gaub
- first_name: Daniel
full_name: Mueller, Daniel J
last_name: Mueller
citation:
ama: Janovjak HL, Kessler M, Oesterhelt D, Gaub H, Mueller D. Unfolding pathways
of native bacteriorhodopsin depend on temperature. EMBO Journal. 2003;22(19):5220-5229.
doi:10.1093/emboj/cdg509
apa: Janovjak, H. L., Kessler, M., Oesterhelt, D., Gaub, H., & Mueller, D. (2003).
Unfolding pathways of native bacteriorhodopsin depend on temperature. EMBO
Journal. Wiley-Blackwell. https://doi.org/10.1093/emboj/cdg509
chicago: Janovjak, Harald L, Max Kessler, Dieter Oesterhelt, Hermann Gaub, and Daniel
Mueller. “Unfolding Pathways of Native Bacteriorhodopsin Depend on Temperature.”
EMBO Journal. Wiley-Blackwell, 2003. https://doi.org/10.1093/emboj/cdg509.
ieee: H. L. Janovjak, M. Kessler, D. Oesterhelt, H. Gaub, and D. Mueller, “Unfolding
pathways of native bacteriorhodopsin depend on temperature,” EMBO Journal,
vol. 22, no. 19. Wiley-Blackwell, pp. 5220–5229, 2003.
ista: Janovjak HL, Kessler M, Oesterhelt D, Gaub H, Mueller D. 2003. Unfolding pathways
of native bacteriorhodopsin depend on temperature. EMBO Journal. 22(19), 5220–5229.
mla: Janovjak, Harald L., et al. “Unfolding Pathways of Native Bacteriorhodopsin
Depend on Temperature.” EMBO Journal, vol. 22, no. 19, Wiley-Blackwell,
2003, pp. 5220–29, doi:10.1093/emboj/cdg509.
short: H.L. Janovjak, M. Kessler, D. Oesterhelt, H. Gaub, D. Mueller, EMBO Journal
22 (2003) 5220–5229.
date_created: 2018-12-11T12:04:50Z
date_published: 2003-01-01T00:00:00Z
date_updated: 2021-01-12T07:51:45Z
day: '01'
doi: 10.1093/emboj/cdg509
extern: 1
intvolume: ' 22'
issue: '19'
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC204492/
month: '01'
oa: 1
page: 5220 - 5229
publication: EMBO Journal
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2506'
quality_controlled: 0
status: public
title: Unfolding pathways of native bacteriorhodopsin depend on temperature
type: journal_article
volume: 22
year: '2003'
...
---
_id: '3804'
abstract:
- lang: eng
text: Kv3 channels are thought to be essential for the fast-spiking (FS) phenotype
in GABAergic interneurons, but how these channels confer the ability to generate
action potentials (APs) at high frequency is unknown. To address this question,
we developed a fast dynamic-clamp system (approximately 50 kHz) that allowed us
to add a Kv3 model conductance to CA1 oriens alveus (OA) interneurons in hippocampal
slices. Selective pharmacological block of Kv3 channels by 0.3 mm 4-aminopyridine
or 1 mm tetraethylammonium ions led to a marked broadening of APs during trains
of short stimuli and a reduction in AP frequency during 1 sec stimuli. The addition
of artificial Kv3 conductance restored the original AP pattern. Subtraction of
Kv3 conductance by dynamic clamp mimicked the effects of the blockers. Application
of artificial Kv3 conductance also led to FS in OA interneurons after complete
K+ channel block and even induced FS in hippocampal pyramidal neurons in the absence
of blockers. Adding artificial Kv3 conductance with altered deactivation kinetics
revealed a nonmonotonic relationship between mean AP frequency and deactivation
rate, with a maximum slightly above the original value. Insertion of artificial
Kv3 conductance with either lowered activation threshold or inactivation also
led to a reduction in the mean AP frequency. However, the mechanisms were distinct.
Shifting the activation threshold induced adaptation, whereas adding inactivation
caused frequency-dependent AP broadening. In conclusion, Kv3 channels are necessary
for the FS phenotype of OA interneurons, and several of their gating properties
appear to be optimized for high-frequency repetitive activity.
author:
- first_name: Cheng
full_name: Lien, Cheng-Chang
last_name: Lien
- first_name: Peter M
full_name: Peter Jonas
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Lien C, Jonas PM. Kv3 potassium conductance is necessary and kinetically optimized
for high-frequency action potential generation in hippocampal interneurons. Journal
of Neuroscience. 2003;23(6):2058-2068.
apa: Lien, C., & Jonas, P. M. (2003). Kv3 potassium conductance is necessary
and kinetically optimized for high-frequency action potential generation in hippocampal
interneurons. Journal of Neuroscience. Society for Neuroscience.
chicago: Lien, Cheng, and Peter M Jonas. “Kv3 Potassium Conductance Is Necessary
and Kinetically Optimized for High-Frequency Action Potential Generation in Hippocampal
Interneurons.” Journal of Neuroscience. Society for Neuroscience, 2003.
ieee: C. Lien and P. M. Jonas, “Kv3 potassium conductance is necessary and kinetically
optimized for high-frequency action potential generation in hippocampal interneurons,”
Journal of Neuroscience, vol. 23, no. 6. Society for Neuroscience, pp.
2058–68, 2003.
ista: Lien C, Jonas PM. 2003. Kv3 potassium conductance is necessary and kinetically
optimized for high-frequency action potential generation in hippocampal interneurons.
Journal of Neuroscience. 23(6), 2058–68.
mla: Lien, Cheng, and Peter M. Jonas. “Kv3 Potassium Conductance Is Necessary and
Kinetically Optimized for High-Frequency Action Potential Generation in Hippocampal
Interneurons.” Journal of Neuroscience, vol. 23, no. 6, Society for Neuroscience,
2003, pp. 2058–68.
short: C. Lien, P.M. Jonas, Journal of Neuroscience 23 (2003) 2058–68.
date_created: 2018-12-11T12:05:16Z
date_published: 2003-01-01T00:00:00Z
date_updated: 2021-01-12T07:52:19Z
day: '01'
extern: 1
intvolume: ' 23'
issue: '6'
month: '01'
page: 2058 - 68
publication: Journal of Neuroscience
publication_status: published
publisher: Society for Neuroscience
publist_id: '2406'
quality_controlled: 0
status: public
title: Kv3 potassium conductance is necessary and kinetically optimized for high-frequency
action potential generation in hippocampal interneurons
type: journal_article
volume: 23
year: '2003'
...
---
_id: '3806'
abstract:
- lang: eng
text: To probe exocytosis at a cortical glutamatergic synapse, we made capacitance
measurements in whole-cell recorded hippocampal mossy fiber terminals. Evaluation
of different methods by using a morphology-based equivalent electrical model revealed
that quantitative capacitance measurements are possible in this presynaptic structure.
Voltage pulses leading to presynaptic Ca2+ inflow evoked large capacitance signals
that showed saturation with increasing pulse duration. The mean peak capacitance
increase was 100 fF, corresponding to a pool of approximately 1,400 releasable
vesicles. Thus hippocampal mossy fiber synapses have a vesicular "maxipool."
Large pool size and rapid vesicle recycling may underlie the uniquely large extent
of activity-dependent plasticity in this synapse.
author:
- first_name: Stefan
full_name: Hallermann, Stefan
last_name: Hallermann
- first_name: Christian
full_name: Pawlu, Christian
last_name: Pawlu
- first_name: Peter M
full_name: Peter Jonas
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
- first_name: Manfred
full_name: Heckmann, Manfred
last_name: Heckmann
citation:
ama: Hallermann S, Pawlu C, Jonas PM, Heckmann M. A large pool of releasable vesicles
in a cortical glutamatergic synapse. PNAS. 2003;100(15):8975-8980. doi:10.1073/pnas.1432836100
apa: Hallermann, S., Pawlu, C., Jonas, P. M., & Heckmann, M. (2003). A large
pool of releasable vesicles in a cortical glutamatergic synapse. PNAS.
National Academy of Sciences. https://doi.org/10.1073/pnas.1432836100
chicago: Hallermann, Stefan, Christian Pawlu, Peter M Jonas, and Manfred Heckmann.
“A Large Pool of Releasable Vesicles in a Cortical Glutamatergic Synapse.” PNAS.
National Academy of Sciences, 2003. https://doi.org/10.1073/pnas.1432836100.
ieee: S. Hallermann, C. Pawlu, P. M. Jonas, and M. Heckmann, “A large pool of releasable
vesicles in a cortical glutamatergic synapse,” PNAS, vol. 100, no. 15.
National Academy of Sciences, pp. 8975–80, 2003.
ista: Hallermann S, Pawlu C, Jonas PM, Heckmann M. 2003. A large pool of releasable
vesicles in a cortical glutamatergic synapse. PNAS. 100(15), 8975–80.
mla: Hallermann, Stefan, et al. “A Large Pool of Releasable Vesicles in a Cortical
Glutamatergic Synapse.” PNAS, vol. 100, no. 15, National Academy of Sciences,
2003, pp. 8975–80, doi:10.1073/pnas.1432836100.
short: S. Hallermann, C. Pawlu, P.M. Jonas, M. Heckmann, PNAS 100 (2003) 8975–80.
date_created: 2018-12-11T12:05:16Z
date_published: 2003-01-01T00:00:00Z
date_updated: 2021-01-12T07:52:20Z
day: '01'
doi: 10.1073/pnas.1432836100
extern: 1
intvolume: ' 100'
issue: '15'
month: '01'
page: 8975 - 80
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '2405'
quality_controlled: 0
status: public
title: A large pool of releasable vesicles in a cortical glutamatergic synapse
type: journal_article
volume: 100
year: '2003'
...
---
_id: '3921'
abstract:
- lang: eng
text: 'Unlike most social insects, many Cardiocondyla ant species have two male
morphs: wingless (ergatoid) males, who remain in the natal nest, and winged males
who disperse but, strangely, before leaving may also mate within the nest. Whereas
ergatoid males are highly intolerant of each other and fight among themselves,
they tend to tolerate their winged counterparts. This is despite the fact that
these winged males, like ergatoid males, represent mating competition. Why should
ergatoid males tolerate their winged rivals? We developed a mathematical model
to address this question. Our model focuses on a number of factors likely toinfluence
whether ergatoid males are tolerant of winged males: ergatoid male–winged male
relatedness, number of virgin queens, number of winged males, and the number of
ejaculates a winged male has (winged males are sperm limited, whereas ergatoid
males have lifelong spermatogenesis). Surprisingly, we found that increasing the
number of virgin queens favors a kill strategy, whereas an increase in the other
factors favors a let-live strategy; these predictions appear true for C. obscurior
and for a number of other Cardiocondyla species. Two further aspects, unequal
insemination success and multiple mating in queens, were also incorporated into
the model and predictions made about their effects on toleration of winged males.
The model is applicable more generally in species that have dimorphic males, such
as some other ants, bees, and fig wasps.'
author:
- first_name: Carl
full_name: Anderson, Carl
last_name: Anderson
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
- first_name: Jürgen
full_name: Heinze, Jürgen
last_name: Heinze
citation:
ama: 'Anderson C, Cremer S, Heinze J. Live and let die: Why fighter males of the
ant Cardiocondyla kill each other but tolerate their winged rivals. Behavioral
Ecology. 2003;14(1):54-62. doi:10.1093/beheco/14.1.54'
apa: 'Anderson, C., Cremer, S., & Heinze, J. (2003). Live and let die: Why fighter
males of the ant Cardiocondyla kill each other but tolerate their winged rivals.
Behavioral Ecology. Oxford University Press. https://doi.org/10.1093/beheco/14.1.54'
chicago: 'Anderson, Carl, Sylvia Cremer, and Jürgen Heinze. “Live and Let Die: Why
Fighter Males of the Ant Cardiocondyla Kill Each Other but Tolerate Their Winged
Rivals.” Behavioral Ecology. Oxford University Press, 2003. https://doi.org/10.1093/beheco/14.1.54.'
ieee: 'C. Anderson, S. Cremer, and J. Heinze, “Live and let die: Why fighter males
of the ant Cardiocondyla kill each other but tolerate their winged rivals,” Behavioral
Ecology, vol. 14, no. 1. Oxford University Press, pp. 54–62, 2003.'
ista: 'Anderson C, Cremer S, Heinze J. 2003. Live and let die: Why fighter males
of the ant Cardiocondyla kill each other but tolerate their winged rivals. Behavioral
Ecology. 14(1), 54–62.'
mla: 'Anderson, Carl, et al. “Live and Let Die: Why Fighter Males of the Ant Cardiocondyla
Kill Each Other but Tolerate Their Winged Rivals.” Behavioral Ecology,
vol. 14, no. 1, Oxford University Press, 2003, pp. 54–62, doi:10.1093/beheco/14.1.54.'
short: C. Anderson, S. Cremer, J. Heinze, Behavioral Ecology 14 (2003) 54–62.
date_created: 2018-12-11T12:05:54Z
date_published: 2003-01-01T00:00:00Z
date_updated: 2021-01-12T07:53:13Z
day: '01'
doi: 10.1093/beheco/14.1.54
extern: '1'
intvolume: ' 14'
issue: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 54 - 62
publication: Behavioral Ecology
publication_status: published
publisher: Oxford University Press
publist_id: '2233'
status: public
title: 'Live and let die: Why fighter males of the ant Cardiocondyla kill each other
but tolerate their winged rivals'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 14
year: '2003'
...
---
_id: '3922'
abstract:
- lang: eng
text: Dispersal is advantageous, but, at the same time, it implies high costs and
risks. Due to these counteracting selection pressures, many species evolved dispersal
polymorphisms, which, in ants, are typically restricted to the female sex (queens).
Male polymorphism is presently only known from a few genera, such as Cardiocondyla,
in which winged dispersing males coexist with wingless fighter males that mate
exclusively inside their maternal nests. We studied the developmental mechanisms
underlying these alternative male morphs and found that, first, male dimorphism
is not genetically determined, but is induced by environmental conditions (decreasing
temperature and density). Second, male morph is not yet fixed at the egg stage,
but it differentiates during larval development. This flexible developmental pattern
of male morphs allows Cardiocondyla ant colonies to react quickly to changes in
their environment. Under good conditions, they invest exclusively in philopatric
wingless males. But, when environmental conditions turn bad, colonies start to
produce winged dispersal males, even though these males require a many times higher
investment by the colony than their much smaller wingless counterparts. Cardiocondyla
ants share this potential of optimal resource allocation with other colonial animals
and some seed dimorphic plants.
author:
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
- first_name: Jürgen
full_name: Heinze, Jürgen
last_name: Heinze
citation:
ama: 'Cremer S, Heinze J. Stress grows wings: Environmental induction of winged
dispersal males in Cardiocondyla ants. Current Biology. 2003;13(3):219-223.
doi:10.1016/S0960-9822(03)00012-5'
apa: 'Cremer, S., & Heinze, J. (2003). Stress grows wings: Environmental induction
of winged dispersal males in Cardiocondyla ants. Current Biology. Cell
Press. https://doi.org/10.1016/S0960-9822(03)00012-5'
chicago: 'Cremer, Sylvia, and Jürgen Heinze. “Stress Grows Wings: Environmental
Induction of Winged Dispersal Males in Cardiocondyla Ants.” Current Biology.
Cell Press, 2003. https://doi.org/10.1016/S0960-9822(03)00012-5.'
ieee: 'S. Cremer and J. Heinze, “Stress grows wings: Environmental induction of
winged dispersal males in Cardiocondyla ants,” Current Biology, vol. 13,
no. 3. Cell Press, pp. 219–223, 2003.'
ista: 'Cremer S, Heinze J. 2003. Stress grows wings: Environmental induction of
winged dispersal males in Cardiocondyla ants. Current Biology. 13(3), 219–223.'
mla: 'Cremer, Sylvia, and Jürgen Heinze. “Stress Grows Wings: Environmental Induction
of Winged Dispersal Males in Cardiocondyla Ants.” Current Biology, vol.
13, no. 3, Cell Press, 2003, pp. 219–23, doi:10.1016/S0960-9822(03)00012-5.'
short: S. Cremer, J. Heinze, Current Biology 13 (2003) 219–223.
date_created: 2018-12-11T12:05:54Z
date_published: 2003-02-04T00:00:00Z
date_updated: 2021-01-12T07:53:13Z
day: '04'
doi: 10.1016/S0960-9822(03)00012-5
extern: '1'
intvolume: ' 13'
issue: '3'
language:
- iso: eng
month: '02'
oa_version: None
page: 219 - 223
publication: Current Biology
publication_status: published
publisher: Cell Press
publist_id: '2234'
status: public
title: 'Stress grows wings: Environmental induction of winged dispersal males in Cardiocondyla
ants'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13
year: '2003'
...