[{"_id":"11860","article_number":"1-10","type":"conference","conference":{"start_date":"2003-05-20","end_date":"2003-05-24","location":"Budapest, Hungary","name":"WWW: International Conference on World Wide Web"},"status":"public","date_updated":"2023-02-21T16:32:40Z","citation":{"chicago":"Henzinger, Monika H, Bay-Wei Chang, Brian Milch, and Sergey Brin. “Query-Free News Search.” In Proceedings of the 12th International Conference on World Wide Web. Association for Computing Machinery, 2003. https://doi.org/10.1145/775152.775154.","ista":"Henzinger MH, Chang B-W, Milch B, Brin S. 2003. Query-free news search. Proceedings of the 12th international conference on World Wide Web. WWW: International Conference on World Wide Web, 1–10.","mla":"Henzinger, Monika H., et al. “Query-Free News Search.” Proceedings of the 12th International Conference on World Wide Web, 1–10, Association for Computing Machinery, 2003, doi:10.1145/775152.775154.","short":"M.H. Henzinger, B.-W. Chang, B. Milch, S. Brin, in:, Proceedings of the 12th International Conference on World Wide Web, Association for Computing Machinery, 2003.","ieee":"M. H. Henzinger, B.-W. Chang, B. Milch, and S. Brin, “Query-free news search,” in Proceedings of the 12th international conference on World Wide Web, Budapest, Hungary, 2003.","apa":"Henzinger, M. H., Chang, B.-W., Milch, B., & Brin, S. (2003). Query-free news search. In Proceedings of the 12th international conference on World Wide Web. Budapest, Hungary: Association for Computing Machinery. https://doi.org/10.1145/775152.775154","ama":"Henzinger MH, Chang B-W, Milch B, Brin S. Query-free news search. In: Proceedings of the 12th International Conference on World Wide Web. Association for Computing Machinery; 2003. doi:10.1145/775152.775154"},"extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"first_name":"Monika H","id":"540c9bbd-f2de-11ec-812d-d04a5be85630","last_name":"Henzinger","orcid":"0000-0002-5008-6530","full_name":"Henzinger, Monika H"},{"full_name":"Chang, Bay-Wei","last_name":"Chang","first_name":"Bay-Wei"},{"first_name":"Brian","last_name":"Milch","full_name":"Milch, Brian"},{"first_name":"Sergey","last_name":"Brin","full_name":"Brin, Sergey"}],"article_processing_charge":"No","title":"Query-free news search","abstract":[{"lang":"eng","text":"Many daily activities present information in the form of a stream of text, and often people can benefit from additional information on the topic discussed. TV broadcast news can be treated as one such stream of text; in this paper we discuss finding news articles on the web that are relevant to news currently being broadcast.We evaluated a variety of algorithms for this problem, looking at the impact of inverse document frequency, stemming, compounds, history, and query length on the relevance and coverage of news articles returned in real time during a broadcast. We also evaluated several postprocessing techniques for improving the precision, including reranking using additional terms, reranking by document similarity, and filtering on document similarity. For the best algorithm, 84%-91% of the articles found were relevant, with at least 64% of the articles being on the exact topic of the broadcast. In addition, a relevant article was found for at least 70% of the topics."}],"oa_version":"None","scopus_import":"1","quality_controlled":"1","publisher":"Association for Computing Machinery","month":"05","publication_identifier":{"isbn":["978-158113680-7"]},"year":"2003","publication_status":"published","day":"01","language":[{"iso":"eng"}],"publication":"Proceedings of the 12th international conference on World Wide Web","related_material":{"record":[{"id":"11904","status":"public","relation":"later_version"}]},"date_published":"2003-05-01T00:00:00Z","doi":"10.1145/775152.775154","date_created":"2022-08-16T08:55:05Z"},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","extern":"1","date_updated":"2023-02-09T12:05:25Z","citation":{"ista":"Henzinger MH, Motwani R, Silverstein C. 2003. Challenges in web search engines. 18th International Joint Conference on Artificial Intelligence. IJCAI: International Joint Conference on Artificial Intelligence, 1573–1579.","chicago":"Henzinger, Monika H, Rajeev Motwani, and Craig Silverstein. “Challenges in Web Search Engines.” In 18th International Joint Conference on Artificial Intelligence, 1573–79. Association for Computing Machinery, 2003.","short":"M.H. Henzinger, R. Motwani, C. Silverstein, in:, 18th International Joint Conference on Artificial Intelligence, Association for Computing Machinery, 2003, pp. 1573–1579.","ieee":"M. H. Henzinger, R. Motwani, and C. Silverstein, “Challenges in web search engines,” in 18th International Joint Conference on Artificial Intelligence, Acapulco, Mexico, 2003, pp. 1573–1579.","apa":"Henzinger, M. H., Motwani, R., & Silverstein, C. (2003). Challenges in web search engines. In 18th International Joint Conference on Artificial Intelligence (pp. 1573–1579). Acapulco, Mexico: Association for Computing Machinery.","ama":"Henzinger MH, Motwani R, Silverstein C. Challenges in web search engines. In: 18th International Joint Conference on Artificial Intelligence. Association for Computing Machinery; 2003:1573-1579.","mla":"Henzinger, Monika H., et al. “Challenges in Web Search Engines.” 18th International Joint Conference on Artificial Intelligence, Association for Computing Machinery, 2003, pp. 1573–79."},"title":"Challenges in web search engines","article_processing_charge":"No","author":[{"id":"540c9bbd-f2de-11ec-812d-d04a5be85630","first_name":"Monika H","orcid":"0000-0002-5008-6530","full_name":"Henzinger, Monika H","last_name":"Henzinger"},{"full_name":"Motwani, Rajeev","last_name":"Motwani","first_name":"Rajeev"},{"full_name":"Silverstein, Craig","last_name":"Silverstein","first_name":"Craig"}],"_id":"11909","status":"public","conference":{"name":"IJCAI: International Joint Conference on Artificial Intelligence","start_date":"2003-08-09","location":"Acapulco, Mexico","end_date":"2003-08-15"},"type":"conference","publication":"18th International Joint Conference on Artificial Intelligence","language":[{"iso":"eng"}],"day":"01","year":"2003","publication_status":"published","publication_identifier":{"issn":["1045-0823"]},"date_created":"2022-08-18T06:40:02Z","date_published":"2003-08-01T00:00:00Z","page":"1573-1579","oa_version":"Published Version","abstract":[{"lang":"eng","text":"This article presents a high-level discussion of some problems that are unique to web search engines. The goal is to raise awareness and stimulate research in these areas."}],"month":"08","oa":1,"main_file_link":[{"open_access":"1","url":"https://www.ijcai.org/Proceedings/03/Papers/278.pdf"}],"quality_controlled":"1","scopus_import":"1","publisher":"Association for Computing Machinery"},{"_id":"1457","type":"journal_article","status":"public","date_updated":"2021-01-12T06:50:52Z","citation":{"chicago":"Hausel, Tamás, and Michael Thaddeus. “Mirror Symmetry, Langlands Duality, and the Hitchin System.” Inventiones Mathematicae. Springer, 2003. https://doi.org/10.1007/s00222-003-0286-7.","ista":"Hausel T, Thaddeus M. 2003. Mirror symmetry, langlands duality, and the Hitchin system. Inventiones Mathematicae. 153(1), 197–229.","mla":"Hausel, Tamás, and Michael Thaddeus. “Mirror Symmetry, Langlands Duality, and the Hitchin System.” Inventiones Mathematicae, vol. 153, no. 1, Springer, 2003, pp. 197–229, doi:10.1007/s00222-003-0286-7.","ieee":"T. Hausel and M. Thaddeus, “Mirror symmetry, langlands duality, and the Hitchin system,” Inventiones Mathematicae, vol. 153, no. 1. Springer, pp. 197–229, 2003.","short":"T. Hausel, M. Thaddeus, Inventiones Mathematicae 153 (2003) 197–229.","apa":"Hausel, T., & Thaddeus, M. (2003). Mirror symmetry, langlands duality, and the Hitchin system. Inventiones Mathematicae. Springer. https://doi.org/10.1007/s00222-003-0286-7","ama":"Hausel T, Thaddeus M. Mirror symmetry, langlands duality, and the Hitchin system. Inventiones Mathematicae. 2003;153(1):197-229. doi:10.1007/s00222-003-0286-7"},"extern":1,"author":[{"last_name":"Hausel","full_name":"Tamas Hausel","first_name":"Tamas","id":"4A0666D8-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Michael","full_name":"Thaddeus, Michael","last_name":"Thaddeus"}],"publist_id":"5738","title":"Mirror symmetry, langlands duality, and the Hitchin system","abstract":[{"text":"Among the major mathematical approaches to mirror symmetry are those of Batyrev-Borisov and Stromdnger-Yau-Zaslow (SYZ). The first is explicit and amenable to computation but is not clearly related to the physical motivation; the second is the opposite. Furthermore, it is far from obvious that mirror partners in one sense will also be mirror partners in the other. This paper concerns a class of examples that can be shown to satisfy the requirements of SYZ, but whose Hodge numbers are also equal. This provides significant evidence in support of SYZ. Moreover, the examples are of great interest in their own right: they are spaces of flat SLr-connections on a smooth curve. The mirror is the corresponding space for the Langlands dual group PGLr. These examples therefore throw a bridge from mirror symmetry to the duality theory of Lie groups and, more broadly, to the geometric Langlands program.","lang":"eng"}],"main_file_link":[{"url":"http://arxiv.org/abs/math/0205236","open_access":"1"}],"oa":1,"quality_controlled":0,"publisher":"Springer","intvolume":" 153","month":"07","year":"2003","publication_status":"published","publication":"Inventiones Mathematicae","day":"01","page":"197 - 229","date_created":"2018-12-11T11:52:08Z","doi":"10.1007/s00222-003-0286-7","issue":"1","date_published":"2003-07-01T00:00:00Z","volume":153},{"page":"303 - 329","date_created":"2018-12-11T11:52:08Z","doi":"10.1090/S0894-0347-02-00417-4","volume":16,"date_published":"2003-04-01T00:00:00Z","issue":"2","year":"2003","publication_status":"published","publication":"Journal of the American Mathematical Society","day":"01","oa":1,"main_file_link":[{"url":"http://arxiv.org/abs/math/0003094","open_access":"1"}],"publisher":"American Mathematical Society","quality_controlled":0,"intvolume":" 16","month":"04","abstract":[{"text":"The moduli space of stable bundles of rank $2$ and degree $1$ on a Riemann surface has rational cohomology generated by the so-called universal classes. The work of Baranovsky, King-Newstead, Siebert-Tian and Zagier provided a complete set of relations between these classes, expressed in terms of a recursion in the genus. This paper accomplishes the same thing for the noncompact moduli spaces of Higgs bundles, in the sense of Hitchin and Simpson. There are many more independent relations than for stable bundles, but in a sense the answer is simpler, since the formulas are completely explicit, not recursive. The results of Kirwan on equivariant cohomology for holomorphic circle actions are of key importance.","lang":"eng"}],"acknowledgement":"The first author was supported by NSF grant DMS-97-29992. The second author was supported by NSF grant DMS-98-08529.","publist_id":"5739","author":[{"full_name":"Tamas Hausel","last_name":"Hausel","id":"4A0666D8-F248-11E8-B48F-1D18A9856A87","first_name":"Tamas"},{"first_name":"Michael","last_name":"Thaddeus","full_name":"Thaddeus, Michael"}],"title":"Relations in the cohomology ring of the moduli space of rank 2 Higgs bundles","date_updated":"2021-01-12T06:50:53Z","citation":{"short":"T. Hausel, M. Thaddeus, Journal of the American Mathematical Society 16 (2003) 303–329.","ieee":"T. Hausel and M. Thaddeus, “Relations in the cohomology ring of the moduli space of rank 2 Higgs bundles,” Journal of the American Mathematical Society, vol. 16, no. 2. American Mathematical Society, pp. 303–329, 2003.","apa":"Hausel, T., & Thaddeus, M. (2003). Relations in the cohomology ring of the moduli space of rank 2 Higgs bundles. Journal of the American Mathematical Society. American Mathematical Society. https://doi.org/10.1090/S0894-0347-02-00417-4","ama":"Hausel T, Thaddeus M. Relations in the cohomology ring of the moduli space of rank 2 Higgs bundles. Journal of the American Mathematical Society. 2003;16(2):303-329. doi:10.1090/S0894-0347-02-00417-4","mla":"Hausel, Tamás, and Michael Thaddeus. “Relations in the Cohomology Ring of the Moduli Space of Rank 2 Higgs Bundles.” Journal of the American Mathematical Society, vol. 16, no. 2, American Mathematical Society, 2003, pp. 303–29, doi:10.1090/S0894-0347-02-00417-4.","ista":"Hausel T, Thaddeus M. 2003. Relations in the cohomology ring of the moduli space of rank 2 Higgs bundles. Journal of the American Mathematical Society. 16(2), 303–329.","chicago":"Hausel, Tamás, and Michael Thaddeus. “Relations in the Cohomology Ring of the Moduli Space of Rank 2 Higgs Bundles.” Journal of the American Mathematical Society. American Mathematical Society, 2003. https://doi.org/10.1090/S0894-0347-02-00417-4."},"extern":1,"type":"journal_article","status":"public","_id":"1458"},{"date_created":"2018-12-11T11:52:09Z","date_published":"2003-04-01T00:00:00Z","issue":"2","volume":235,"doi":"10.1007/s00220-003-0806-8","page":"275 - 288","publication":"Communications in Mathematical Physics","day":"01","publication_status":"published","year":"2003","intvolume":" 235","month":"04","main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/hep-th/0207196"}],"oa":1,"publisher":"Springer","quality_controlled":0,"acknowledgement":"We would like to acknowledge the financial support by Prof. P. Major (R ́ enyi Institute, Hungary) from his OTKA grant No. T26176 and of the Miller Institute for Basic Research in Science at UC Berkeley.","abstract":[{"lang":"eng","text":"In this paper we explicitly calculate the analogue of the 't Hooft SU (2) Yang-Mills instantons on Gibbons-Hawking multi-centered gravitational instantons, which come in two parallel families: the multi-Eguchi-Hanson, or Ak ALE gravitational instantons and the multi-Taub-NUT spaces, or Ak ALF gravitational instantons. We calculate their energy and find the reducible ones. Following Kronheimer we also exploit the U(1) invariance of our solutions and study the corresponding explicit singular SU (2) magnetic monopole solutions of the Bogomolny equations on flat ℝ3."}],"title":"On Yang-Mills instantons over multi-centered gravitational instantons","publist_id":"5740","author":[{"last_name":"Etesi","full_name":"Etesi, Gábor","first_name":"Gábor"},{"first_name":"Tamas","id":"4A0666D8-F248-11E8-B48F-1D18A9856A87","full_name":"Tamas Hausel","last_name":"Hausel"}],"extern":1,"date_updated":"2021-01-12T06:50:53Z","citation":{"chicago":"Etesi, Gábor, and Tamás Hausel. “On Yang-Mills Instantons over Multi-Centered Gravitational Instantons.” Communications in Mathematical Physics. Springer, 2003. https://doi.org/10.1007/s00220-003-0806-8.","ista":"Etesi G, Hausel T. 2003. On Yang-Mills instantons over multi-centered gravitational instantons. Communications in Mathematical Physics. 235(2), 275–288.","mla":"Etesi, Gábor, and Tamás Hausel. “On Yang-Mills Instantons over Multi-Centered Gravitational Instantons.” Communications in Mathematical Physics, vol. 235, no. 2, Springer, 2003, pp. 275–88, doi:10.1007/s00220-003-0806-8.","ama":"Etesi G, Hausel T. On Yang-Mills instantons over multi-centered gravitational instantons. Communications in Mathematical Physics. 2003;235(2):275-288. doi:10.1007/s00220-003-0806-8","apa":"Etesi, G., & Hausel, T. (2003). On Yang-Mills instantons over multi-centered gravitational instantons. Communications in Mathematical Physics. Springer. https://doi.org/10.1007/s00220-003-0806-8","short":"G. Etesi, T. Hausel, Communications in Mathematical Physics 235 (2003) 275–288.","ieee":"G. Etesi and T. Hausel, “On Yang-Mills instantons over multi-centered gravitational instantons,” Communications in Mathematical Physics, vol. 235, no. 2. Springer, pp. 275–288, 2003."},"status":"public","type":"journal_article","_id":"1459"},{"year":"2003","publication_status":"published","day":"01","language":[{"iso":"eng"}],"publication":"Proceedings of the Bonn session in analytic number theory and diophantine equations","volume":360,"date_published":"2003-01-01T00:00:00Z","date_created":"2018-12-11T11:44:58Z","abstract":[{"text":"For any number field k, upper bounds are established for the number of k-rational points of bounded height on non-singular del Pezzo surfaces defined over k, which are equipped with suitable conic bundle structures over k.","lang":"eng"}],"oa_version":"None","publisher":"Mathematisches Institut der Universität Bonn","alternative_title":["Bonner mathematische Schriften"],"oa":1,"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1311.1665"}],"month":"01","intvolume":" 360","citation":{"chicago":"Browning, Timothy D, and M Swarbick Jones. “Counting Rational Points on Del Pezzo Surfaces of Degree 5.” Proceedings of the Bonn Session in Analytic Number Theory and Diophantine Equations. Mathematisches Institut der Universität Bonn, 2003.","ista":"Browning TD, Swarbick Jones M. 2003. Counting rational points on del Pezzo surfaces of degree 5. Proceedings of the Bonn session in analytic number theory and diophantine equations. 360.","mla":"Browning, Timothy D., and M. Swarbick Jones. “Counting Rational Points on Del Pezzo Surfaces of Degree 5.” Proceedings of the Bonn Session in Analytic Number Theory and Diophantine Equations, vol. 360, Mathematisches Institut der Universität Bonn, 2003.","ieee":"T. D. Browning and M. Swarbick Jones, “Counting rational points on del Pezzo surfaces of degree 5,” Proceedings of the Bonn session in analytic number theory and diophantine equations, vol. 360. Mathematisches Institut der Universität Bonn, 2003.","short":"T.D. Browning, M. Swarbick Jones, Proceedings of the Bonn Session in Analytic Number Theory and Diophantine Equations 360 (2003).","ama":"Browning TD, Swarbick Jones M. Counting rational points on del Pezzo surfaces of degree 5. Proceedings of the Bonn session in analytic number theory and diophantine equations. 2003;360.","apa":"Browning, T. D., & Swarbick Jones, M. (2003). Counting rational points on del Pezzo surfaces of degree 5. Proceedings of the Bonn Session in Analytic Number Theory and Diophantine Equations. Mathematisches Institut der Universität Bonn."},"date_updated":"2021-01-12T06:52:20Z","extern":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"last_name":"Browning","orcid":"0000-0002-8314-0177","full_name":"Browning, Timothy D","first_name":"Timothy D","id":"35827D50-F248-11E8-B48F-1D18A9856A87"},{"first_name":"M","last_name":"Swarbick Jones","full_name":"Swarbick Jones, M"}],"publist_id":"7755","external_id":{"arxiv":["1311.1665"]},"title":"Counting rational points on del Pezzo surfaces of degree 5","_id":"166","type":"journal_article","status":"public"},{"date_updated":"2021-01-12T06:54:21Z","citation":{"mla":"Holt, Peter, et al. “The Location of NuoL and NuoM Subunits in the Membrane Domain of the Escherichia Coli Complex I: Implications for the Mechanism of Proton Pumping.” Journal of Biological Chemistry, vol. 278, no. 44, American Society for Biochemistry and Molecular Biology, 2003, pp. 43114–20, doi:10.1074/jbc.M308247200.","short":"P. Holt, D. Morgan, L.A. Sazanov, Journal of Biological Chemistry 278 (2003) 43114–43120.","ieee":"P. Holt, D. Morgan, and L. A. Sazanov, “The location of NuoL and NuoM subunits in the membrane domain of the Escherichia coli Complex I: implications for the mechanism of proton pumping,” Journal of Biological Chemistry, vol. 278, no. 44. American Society for Biochemistry and Molecular Biology, pp. 43114–43120, 2003.","apa":"Holt, P., Morgan, D., & Sazanov, L. A. (2003). The location of NuoL and NuoM subunits in the membrane domain of the Escherichia coli Complex I: implications for the mechanism of proton pumping. Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology. https://doi.org/10.1074/jbc.M308247200","ama":"Holt P, Morgan D, Sazanov LA. The location of NuoL and NuoM subunits in the membrane domain of the Escherichia coli Complex I: implications for the mechanism of proton pumping. Journal of Biological Chemistry. 2003;278(44):43114-43120. doi:10.1074/jbc.M308247200","chicago":"Holt, Peter, David Morgan, and Leonid A Sazanov. “The Location of NuoL and NuoM Subunits in the Membrane Domain of the Escherichia Coli Complex I: Implications for the Mechanism of Proton Pumping.” Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology, 2003. https://doi.org/10.1074/jbc.M308247200.","ista":"Holt P, Morgan D, Sazanov LA. 2003. The location of NuoL and NuoM subunits in the membrane domain of the Escherichia coli Complex I: implications for the mechanism of proton pumping. Journal of Biological Chemistry. 278(44), 43114–43120."},"extern":1,"publist_id":"5124","author":[{"first_name":"Peter","full_name":"Holt, Peter J","last_name":"Holt"},{"first_name":"David","last_name":"Morgan","full_name":"Morgan, David J"},{"first_name":"Leonid A","id":"338D39FE-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-0977-7989","full_name":"Leonid Sazanov","last_name":"Sazanov"}],"title":"The location of NuoL and NuoM subunits in the membrane domain of the Escherichia coli Complex I: implications for the mechanism of proton pumping","_id":"1959","type":"journal_article","status":"public","year":"2003","publication_status":"published","publication":"Journal of Biological Chemistry","day":"31","page":"43114 - 43120","date_created":"2018-12-11T11:54:55Z","volume":278,"date_published":"2003-10-31T00:00:00Z","doi":"10.1074/jbc.M308247200","issue":"44","abstract":[{"text":"The molecular organization of bacterial NADH: ubiquinone oxidoreductase (complex I or NDH-1) is not established, apart from a rough separation into dehydrogenase, connecting and membrane domains. In this work, complex I was purified from Escherichia coli and fragmented by replacing dodecylmaltoside with other detergents. Exchange into decyl maltoside led to the removal of the hydrophobic subunit NuoL from the otherwise intact complex. Diheptanoyl phosphocholine led to the loss of NuoL and NuoM subunits, whereas other subunits remained in the complex. The presence of N,N-dimethyldodecylamine N-oxide or Triton X-100 led to further disruption of the membrane domain into fragments containing NuoL/M/N, NuoA/K/N, and NuoH/J subunits. Among the hydrophilic subunits, NuoCD was most readily dissociated from the complex, whereas NuoB was partially dissociated from the peripheral arm assembly in N,N-dimethyldodecylamine N-oxide. A model of subunit arrangement in bacterial complex I based on these data is proposed. Subunits NuoL and NuoM, which are homologous to antiporters and are implicated in proton pumping, are located at the distal end of the membrane arm, spatially separated from the redox centers of the peripheral arm. This is consistent with proposals that the mechanism of proton pumping by complex I is likely to involve long range conformational changes.","lang":"eng"}],"acknowledgement":"his work was supported by the Medical Research Council.","publisher":"American Society for Biochemistry and Molecular Biology","quality_controlled":0,"intvolume":" 278","month":"10"},{"publisher":"American Society for Biochemistry and Molecular Biology","quality_controlled":0,"month":"05","intvolume":" 278","abstract":[{"lang":"eng","text":"NADH-ubiquinone oxidoreductase (complex I or NDH-1) was purified from the BL21 strain of Escherichia coli using an improved procedure. The complex was effectively stabilized by addition of divalent cations and lipids, making the preparation suitable for structural studies. The ubiquinone reductase activity of the enzyme was fully restored by addition of native E. coli lipids. Two different two-dimensional crystal forms, with p2 and p3 symmetry, were obtained using lipids containing native E. coli extracts. Analysis of the crystals showed that they are formed by fully intact complex I in an L-shaped conformation. Activity assays and single particle analysis indicated that complex I maintains this structure in detergent solution and does not adopt a different conformation in the active state. Thus, we provide the first experimental evidence that complex I from E. coli has an L-shape in a lipid bilayer and confirm that this is also the case for the active enzyme in solution. This suggests strongly that bacterial complex I exists in an L-shaped conformation in vivo. Our results also indicate that native lipids play an important role in the activation, stabilization and, as a consequence, crystallization of purified complex I from E. coli."}],"page":"19483 - 19491","doi":"10.1074/jbc.M208959200","volume":278,"date_published":"2003-05-23T00:00:00Z","issue":"21","date_created":"2018-12-11T11:54:55Z","publication_status":"published","year":"2003","day":"23","publication":"Journal of Biological Chemistry","type":"journal_article","status":"public","_id":"1960","author":[{"last_name":"Sazanov","full_name":"Leonid Sazanov","orcid":"0000-0002-0977-7989","first_name":"Leonid A","id":"338D39FE-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Joe","last_name":"Carroll","full_name":"Carroll, Joe D"},{"last_name":"Holt","full_name":"Holt, Peter J","first_name":"Peter"},{"first_name":"Laurence","full_name":"Toime, Laurence J","last_name":"Toime"},{"last_name":"Fearnley","full_name":"Fearnley, Ian M","first_name":"Ian"}],"publist_id":"5125","title":"A role for native lipids in the stabilization and two dimensional crystallization of the Escherichia coli NADH ubiquinone oxidoreductase (complex I)","citation":{"mla":"Sazanov, Leonid A., et al. “A Role for Native Lipids in the Stabilization and Two Dimensional Crystallization of the Escherichia Coli NADH Ubiquinone Oxidoreductase (Complex I).” Journal of Biological Chemistry, vol. 278, no. 21, American Society for Biochemistry and Molecular Biology, 2003, pp. 19483–91, doi:10.1074/jbc.M208959200.","ieee":"L. A. Sazanov, J. Carroll, P. Holt, L. Toime, and I. Fearnley, “A role for native lipids in the stabilization and two dimensional crystallization of the Escherichia coli NADH ubiquinone oxidoreductase (complex I),” Journal of Biological Chemistry, vol. 278, no. 21. American Society for Biochemistry and Molecular Biology, pp. 19483–19491, 2003.","short":"L.A. Sazanov, J. Carroll, P. Holt, L. Toime, I. Fearnley, Journal of Biological Chemistry 278 (2003) 19483–19491.","apa":"Sazanov, L. A., Carroll, J., Holt, P., Toime, L., & Fearnley, I. (2003). A role for native lipids in the stabilization and two dimensional crystallization of the Escherichia coli NADH ubiquinone oxidoreductase (complex I). Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology. https://doi.org/10.1074/jbc.M208959200","ama":"Sazanov LA, Carroll J, Holt P, Toime L, Fearnley I. A role for native lipids in the stabilization and two dimensional crystallization of the Escherichia coli NADH ubiquinone oxidoreductase (complex I). Journal of Biological Chemistry. 2003;278(21):19483-19491. doi:10.1074/jbc.M208959200","chicago":"Sazanov, Leonid A, Joe Carroll, Peter Holt, Laurence Toime, and Ian Fearnley. “A Role for Native Lipids in the Stabilization and Two Dimensional Crystallization of the Escherichia Coli NADH Ubiquinone Oxidoreductase (Complex I).” Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology, 2003. https://doi.org/10.1074/jbc.M208959200.","ista":"Sazanov LA, Carroll J, Holt P, Toime L, Fearnley I. 2003. A role for native lipids in the stabilization and two dimensional crystallization of the Escherichia coli NADH ubiquinone oxidoreductase (complex I). Journal of Biological Chemistry. 278(21), 19483–19491."},"date_updated":"2021-01-12T06:54:21Z","extern":1},{"_id":"205","status":"public","type":"journal_article","extern":1,"citation":{"ista":"Browning TD. 2003. Counting rational points on cubic and quartic surfaces. Acta Arithmetica. 108(3), 275–295.","chicago":"Browning, Timothy D. “Counting Rational Points on Cubic and Quartic Surfaces.” Acta Arithmetica. Instytut Matematyczny, 2003. https://doi.org/10.4064/aa108-3-7.","apa":"Browning, T. D. (2003). Counting rational points on cubic and quartic surfaces. Acta Arithmetica. Instytut Matematyczny. https://doi.org/10.4064/aa108-3-7","ama":"Browning TD. Counting rational points on cubic and quartic surfaces. Acta Arithmetica. 2003;108(3):275-295. doi:10.4064/aa108-3-7","short":"T.D. Browning, Acta Arithmetica 108 (2003) 275–295.","ieee":"T. D. Browning, “Counting rational points on cubic and quartic surfaces,” Acta Arithmetica, vol. 108, no. 3. Instytut Matematyczny, pp. 275–295, 2003.","mla":"Browning, Timothy D. “Counting Rational Points on Cubic and Quartic Surfaces.” Acta Arithmetica, vol. 108, no. 3, Instytut Matematyczny, 2003, pp. 275–95, doi:10.4064/aa108-3-7."},"date_updated":"2021-01-12T06:54:58Z","title":"Counting rational points on cubic and quartic surfaces","publist_id":"7707","author":[{"last_name":"Browning","full_name":"Timothy Browning","orcid":"0000-0002-8314-0177","first_name":"Timothy D","id":"35827D50-F248-11E8-B48F-1D18A9856A87"}],"intvolume":" 108","month":"01","publisher":"Instytut Matematyczny","quality_controlled":0,"publication":"Acta Arithmetica","day":"01","year":"2003","publication_status":"published","date_created":"2018-12-11T11:45:12Z","issue":"3","volume":108,"doi":"10.4064/aa108-3-7","date_published":"2003-01-01T00:00:00Z","page":"275 - 295"},{"date_created":"2018-12-11T11:45:12Z","issue":"1","volume":54,"doi":"10.1093/qjmath/54.1.33","date_published":"2003-03-01T00:00:00Z","page":"33 - 39","publication":"Quarterly Journal of Mathematics","day":"01","publication_status":"published","year":"2003","intvolume":" 54","month":"03","publisher":"Unknown","quality_controlled":0,"abstract":[{"text":"Let T ⊂ ℙ 4 be a non-singular threefold of degree at least four. Then we show that the number of points in T(ℚ), with height at most B, is o(B 3) or B → ∞.","lang":"eng"}],"title":"A note on the distribution of rational points on threefolds","publist_id":"7706","author":[{"last_name":"Browning","orcid":"0000-0002-8314-0177","full_name":"Timothy Browning","id":"35827D50-F248-11E8-B48F-1D18A9856A87","first_name":"Timothy D"}],"extern":1,"citation":{"mla":"Browning, Timothy D. “A Note on the Distribution of Rational Points on Threefolds.” Quarterly Journal of Mathematics, vol. 54, no. 1, Unknown, 2003, pp. 33–39, doi:10.1093/qjmath/54.1.33.","ama":"Browning TD. A note on the distribution of rational points on threefolds. Quarterly Journal of Mathematics. 2003;54(1):33-39. doi:10.1093/qjmath/54.1.33","apa":"Browning, T. D. (2003). A note on the distribution of rational points on threefolds. Quarterly Journal of Mathematics. Unknown. https://doi.org/10.1093/qjmath/54.1.33","ieee":"T. D. Browning, “A note on the distribution of rational points on threefolds,” Quarterly Journal of Mathematics, vol. 54, no. 1. Unknown, pp. 33–39, 2003.","short":"T.D. Browning, Quarterly Journal of Mathematics 54 (2003) 33–39.","chicago":"Browning, Timothy D. “A Note on the Distribution of Rational Points on Threefolds.” Quarterly Journal of Mathematics. Unknown, 2003. https://doi.org/10.1093/qjmath/54.1.33.","ista":"Browning TD. 2003. A note on the distribution of rational points on threefolds. Quarterly Journal of Mathematics. 54(1), 33–39."},"date_updated":"2021-01-12T06:55:02Z","status":"public","type":"journal_article","_id":"206"},{"date_created":"2018-12-11T11:45:12Z","date_published":"2003-05-01T00:00:00Z","volume":134,"issue":"3","doi":"10.1017/S0305004102006382","page":"385 - 395","language":[{"iso":"eng"}],"publication":"Mathematical Proceedings of the Cambridge Philosophical Society","day":"01","publication_status":"published","year":"2003","intvolume":" 134","month":"05","publisher":"Cambridge University Press","quality_controlled":"1","oa_version":"None","title":"Sums of four biquadrates","author":[{"id":"35827D50-F248-11E8-B48F-1D18A9856A87","first_name":"Timothy D","last_name":"Browning","full_name":"Browning, Timothy D","orcid":"0000-0002-8314-0177"}],"publist_id":"7704","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","extern":"1","date_updated":"2021-01-12T06:55:07Z","citation":{"chicago":"Browning, Timothy D. “Sums of Four Biquadrates.” Mathematical Proceedings of the Cambridge Philosophical Society. Cambridge University Press, 2003. https://doi.org/10.1017/S0305004102006382.","ista":"Browning TD. 2003. Sums of four biquadrates. Mathematical Proceedings of the Cambridge Philosophical Society. 134(3), 385–395.","mla":"Browning, Timothy D. “Sums of Four Biquadrates.” Mathematical Proceedings of the Cambridge Philosophical Society, vol. 134, no. 3, Cambridge University Press, 2003, pp. 385–95, doi:10.1017/S0305004102006382.","ieee":"T. D. Browning, “Sums of four biquadrates,” Mathematical Proceedings of the Cambridge Philosophical Society, vol. 134, no. 3. Cambridge University Press, pp. 385–395, 2003.","short":"T.D. Browning, Mathematical Proceedings of the Cambridge Philosophical Society 134 (2003) 385–395.","ama":"Browning TD. Sums of four biquadrates. Mathematical Proceedings of the Cambridge Philosophical Society. 2003;134(3):385-395. doi:10.1017/S0305004102006382","apa":"Browning, T. D. (2003). Sums of four biquadrates. Mathematical Proceedings of the Cambridge Philosophical Society. Cambridge University Press. https://doi.org/10.1017/S0305004102006382"},"status":"public","type":"journal_article","_id":"207"},{"abstract":[{"lang":"eng","text":"For any ε > 0 and any diagonal quadratic form Q ∈ ℤ[x 1, x 2, x 3, x 4] with a square-free discriminant of modulus Δ Q ≠ 0, we establish the uniform estimate ≪ε B 3/2+ε + B 2+ε/Δ Q 1/6 for the number of rational points of height at most B lying in the projective surface Q = 0."}],"publisher":"Oxford University Press","quality_controlled":0,"month":"03","intvolume":" 54","year":"2003","publication_status":"published","day":"01","publication":"Quarterly Journal of Mathematics","page":"11 - 31","doi":"10.1093/qjmath/54.1.11","issue":"1","volume":54,"date_published":"2003-03-01T00:00:00Z","date_created":"2018-12-11T11:45:13Z","_id":"208","type":"journal_article","status":"public","date_updated":"2021-01-12T06:55:10Z","citation":{"apa":"Browning, T. D. (2003). Counting rational points on diagonal quadratic surfaces. Quarterly Journal of Mathematics. Oxford University Press. https://doi.org/10.1093/qjmath/54.1.11","ama":"Browning TD. Counting rational points on diagonal quadratic surfaces. Quarterly Journal of Mathematics. 2003;54(1):11-31. doi:10.1093/qjmath/54.1.11","short":"T.D. Browning, Quarterly Journal of Mathematics 54 (2003) 11–31.","ieee":"T. D. Browning, “Counting rational points on diagonal quadratic surfaces,” Quarterly Journal of Mathematics, vol. 54, no. 1. Oxford University Press, pp. 11–31, 2003.","mla":"Browning, Timothy D. “Counting Rational Points on Diagonal Quadratic Surfaces.” Quarterly Journal of Mathematics, vol. 54, no. 1, Oxford University Press, 2003, pp. 11–31, doi:10.1093/qjmath/54.1.11.","ista":"Browning TD. 2003. Counting rational points on diagonal quadratic surfaces. Quarterly Journal of Mathematics. 54(1), 11–31.","chicago":"Browning, Timothy D. “Counting Rational Points on Diagonal Quadratic Surfaces.” Quarterly Journal of Mathematics. Oxford University Press, 2003. https://doi.org/10.1093/qjmath/54.1.11."},"extern":1,"author":[{"orcid":"0000-0002-8314-0177","full_name":"Timothy Browning","last_name":"Browning","id":"35827D50-F248-11E8-B48F-1D18A9856A87","first_name":"Timothy D"}],"publist_id":"7705","title":"Counting rational points on diagonal quadratic surfaces"},{"extern":1,"date_updated":"2021-01-12T06:56:52Z","citation":{"ieee":"É. Lieb and R. Seiringer, “Bose-Einstein condensation of dilute gases in traps ,” presented at the Differential Equations and Mathematical Physics, 2003, vol. 327, pp. 239–250.","short":"É. Lieb, R. Seiringer, in:, Y. Karpeshina, R. Weikard, Y. Zeng (Eds.), American Mathematical Society, 2003, pp. 239–250.","apa":"Lieb, É., & Seiringer, R. (2003). Bose-Einstein condensation of dilute gases in traps . In Y. Karpeshina, R. Weikard, & Y. Zeng (Eds.) (Vol. 327, pp. 239–250). Presented at the Differential Equations and Mathematical Physics, American Mathematical Society. https://doi.org/10.1090/conm/327/05818","ama":"Lieb É, Seiringer R. Bose-Einstein condensation of dilute gases in traps . In: Karpeshina Y, Weikard R, Zeng Y, eds. Vol 327. American Mathematical Society; 2003:239-250. doi:10.1090/conm/327/05818","mla":"Lieb, Élliott, and Robert Seiringer. Bose-Einstein Condensation of Dilute Gases in Traps . Edited by Yulia Karpeshina et al., vol. 327, American Mathematical Society, 2003, pp. 239–50, doi:10.1090/conm/327/05818.","ista":"Lieb É, Seiringer R. 2003. Bose-Einstein condensation of dilute gases in traps . Differential Equations and Mathematical Physics, Contemporary Mathematics, vol. 327, 239–250.","chicago":"Lieb, Élliott, and Robert Seiringer. “Bose-Einstein Condensation of Dilute Gases in Traps .” edited by Yulia Karpeshina, Rudi Weikard, and Yanni Zeng, 327:239–50. American Mathematical Society, 2003. https://doi.org/10.1090/conm/327/05818."},"editor":[{"first_name":"Yulia","last_name":"Karpeshina","full_name":"Karpeshina, Yulia"},{"first_name":"Rudi","full_name":"Weikard, Rudi","last_name":"Weikard"},{"first_name":"Yanni","full_name":"Zeng, Yanni","last_name":"Zeng"}],"title":"Bose-Einstein condensation of dilute gases in traps ","author":[{"full_name":"Lieb, Élliott H","last_name":"Lieb","first_name":"Élliott"},{"first_name":"Robert","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","full_name":"Robert Seiringer","orcid":"0000-0002-6781-0521","last_name":"Seiringer"}],"publist_id":"4589","_id":"2337","status":"public","conference":{"name":"Differential Equations and Mathematical Physics"},"type":"conference","day":"01","year":"2003","publication_status":"published","date_created":"2018-12-11T11:57:04Z","doi":"10.1090/conm/327/05818","date_published":"2003-01-01T00:00:00Z","volume":327,"page":"239 - 250","intvolume":" 327","month":"01","oa":1,"main_file_link":[{"url":"http://arxiv.org/abs/math-ph/0210028","open_access":"1"}],"quality_controlled":0,"alternative_title":["Contemporary Mathematics"],"publisher":"American Mathematical Society"},{"_id":"2357","type":"journal_article","status":"public","citation":{"ieee":"É. Lieb, R. Seiringer, and J. Yngvason, “Poincaré inequalities in punctured domains,” Annals of Mathematics, vol. 158, no. 3. Princeton University Press, pp. 1067–1080, 2003.","short":"É. Lieb, R. Seiringer, J. Yngvason, Annals of Mathematics 158 (2003) 1067–1080.","ama":"Lieb É, Seiringer R, Yngvason J. Poincaré inequalities in punctured domains. Annals of Mathematics. 2003;158(3):1067-1080. doi:10.4007/annals.2003.158.1067 ","apa":"Lieb, É., Seiringer, R., & Yngvason, J. (2003). Poincaré inequalities in punctured domains. Annals of Mathematics. Princeton University Press. https://doi.org/10.4007/annals.2003.158.1067 ","mla":"Lieb, Élliott, et al. “Poincaré Inequalities in Punctured Domains.” Annals of Mathematics, vol. 158, no. 3, Princeton University Press, 2003, pp. 1067–80, doi:10.4007/annals.2003.158.1067 .","ista":"Lieb É, Seiringer R, Yngvason J. 2003. Poincaré inequalities in punctured domains. Annals of Mathematics. 158(3), 1067–1080.","chicago":"Lieb, Élliott, Robert Seiringer, and Jakob Yngvason. “Poincaré Inequalities in Punctured Domains.” Annals of Mathematics. Princeton University Press, 2003. https://doi.org/10.4007/annals.2003.158.1067 ."},"date_updated":"2021-01-12T06:57:00Z","extern":1,"publist_id":"4570","author":[{"first_name":"Élliott","last_name":"Lieb","full_name":"Lieb, Élliott H"},{"first_name":"Robert","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","last_name":"Seiringer","full_name":"Robert Seiringer","orcid":"0000-0002-6781-0521"},{"first_name":"Jakob","full_name":"Yngvason, Jakob","last_name":"Yngvason"}],"title":"Poincaré inequalities in punctured domains","abstract":[{"text":"The classic Poincaré inequality bounds the L q-norm of a function f in a bounded domain Ω ⊂ ℝ n in terms of some L p-norm of its gradient in Ω. We generalize this in two ways: In the first generalization we remove a set Τ from Ω and concentrate our attention on Λ = Ω \\ Τ. This new domain might not even be connected and hence no Poincaré inequality can generally hold for it, or if it does hold it might have a very bad constant. This is so even if the volume of Τ is arbitrarily small. A Poincaré inequality does hold, however, if one makes the additional assumption that f has a finite L p gradient norm on the whole of Ω, not just on Λ. The important point is that the Poincaré inequality thus obtained bounds the L q-norm of f in terms of the L p gradient norm on Λ (not Ω) plus an additional term that goes to zero as the volume of Τ goes to zero. This error term depends on Τ only through its volume. Apart from this additive error term, the constant in the inequality remains that of the 'nice' domain Ω. In the second generalization we are given a vector field A and replace ∇ by ∇ + iA(x) (geometrically, a connection on a U(1) bundle). Unlike the A = 0 case, the infimum of ∥(∇ + iA)f∥ p over all f with a given ∥f∥ q is in general not zero. This permits an improvement of the inequality by the addition of a term whose sharp value we derive. We describe some open problems that arise from these generalizations.","lang":"eng"}],"quality_controlled":0,"publisher":"Princeton University Press","oa":1,"main_file_link":[{"url":"http://arxiv.org/abs/math/0205088","open_access":"1"}],"month":"11","intvolume":" 158","publication_status":"published","year":"2003","day":"01","publication":"Annals of Mathematics","page":"1067 - 1080","date_published":"2003-11-01T00:00:00Z","issue":"3","doi":"10.4007/annals.2003.158.1067 ","volume":158,"date_created":"2018-12-11T11:57:11Z"},{"publication":"Journal of Physics A: Mathematical and Theoretical","day":"19","year":"2003","publication_status":"published","date_created":"2018-12-11T11:57:10Z","doi":"10.1088/0305-4470/36/37/312","issue":"37","date_published":"2003-09-19T00:00:00Z","volume":36,"page":"9755 - 9778","abstract":[{"lang":"eng","text":"We investigate the ground state properties of a gas of interacting particles confined in an external potential in three dimensions and subject to rotation around an axis of symmetry. We consider the Gross-Pitaevskii (GP) limit of a dilute gas. Analysing both the absolute and the bosonic ground states of the system, we show, in particular, their different behaviour for a certain range of parameters. This parameter range is determined by the question whether the rotational symmetry in the minimizer of the GP functional is broken or not. For the absolute ground state, we prove that in the GP limit a modified GP functional depending on density matrices correctly describes the energy and reduced density matrices, independent of symmetry breaking. For the bosonic ground state this holds true if and only if the symmetry is unbroken."}],"intvolume":" 36","month":"09","oa":1,"main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/math-ph/0306022"}],"quality_controlled":0,"publisher":"IOP Publishing Ltd.","extern":1,"citation":{"chicago":"Seiringer, Robert. “Ground State Asymptotics of a Dilute, Rotating Gas.” Journal of Physics A: Mathematical and Theoretical. IOP Publishing Ltd., 2003. https://doi.org/10.1088/0305-4470/36/37/312.","ista":"Seiringer R. 2003. Ground state asymptotics of a dilute, rotating gas. Journal of Physics A: Mathematical and Theoretical. 36(37), 9755–9778.","mla":"Seiringer, Robert. “Ground State Asymptotics of a Dilute, Rotating Gas.” Journal of Physics A: Mathematical and Theoretical, vol. 36, no. 37, IOP Publishing Ltd., 2003, pp. 9755–78, doi:10.1088/0305-4470/36/37/312.","ama":"Seiringer R. Ground state asymptotics of a dilute, rotating gas. Journal of Physics A: Mathematical and Theoretical. 2003;36(37):9755-9778. doi:10.1088/0305-4470/36/37/312","apa":"Seiringer, R. (2003). Ground state asymptotics of a dilute, rotating gas. Journal of Physics A: Mathematical and Theoretical. IOP Publishing Ltd. https://doi.org/10.1088/0305-4470/36/37/312","ieee":"R. Seiringer, “Ground state asymptotics of a dilute, rotating gas,” Journal of Physics A: Mathematical and Theoretical, vol. 36, no. 37. IOP Publishing Ltd., pp. 9755–9778, 2003.","short":"R. Seiringer, Journal of Physics A: Mathematical and Theoretical 36 (2003) 9755–9778."},"date_updated":"2021-01-12T06:56:59Z","title":"Ground state asymptotics of a dilute, rotating gas","publist_id":"4572","author":[{"first_name":"Robert","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6781-0521","full_name":"Robert Seiringer","last_name":"Seiringer"}],"_id":"2354","status":"public","type":"journal_article"},{"title":"One-dimensional Bosons in three-dimensional traps","author":[{"first_name":"Élliott","last_name":"Lieb","full_name":"Lieb, Élliott H"},{"full_name":"Robert Seiringer","orcid":"0000-0002-6781-0521","last_name":"Seiringer","first_name":"Robert","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Jakob","last_name":"Yngvason","full_name":"Yngvason, Jakob"}],"publist_id":"4571","extern":1,"date_updated":"2021-01-12T06:57:00Z","citation":{"mla":"Lieb, Élliott, et al. “One-Dimensional Bosons in Three-Dimensional Traps.” Physical Review Letters, vol. 91, no. 15, American Physical Society, 2003, pp. 1504011–14, doi:10.1103/PhysRevLett.91.150401.","ama":"Lieb É, Seiringer R, Yngvason J. One-dimensional Bosons in three-dimensional traps. Physical Review Letters. 2003;91(15):1504011-1504014. doi:10.1103/PhysRevLett.91.150401","apa":"Lieb, É., Seiringer, R., & Yngvason, J. (2003). One-dimensional Bosons in three-dimensional traps. Physical Review Letters. American Physical Society. https://doi.org/10.1103/PhysRevLett.91.150401","ieee":"É. Lieb, R. Seiringer, and J. Yngvason, “One-dimensional Bosons in three-dimensional traps,” Physical Review Letters, vol. 91, no. 15. American Physical Society, pp. 1504011–1504014, 2003.","short":"É. Lieb, R. Seiringer, J. Yngvason, Physical Review Letters 91 (2003) 1504011–1504014.","chicago":"Lieb, Élliott, Robert Seiringer, and Jakob Yngvason. “One-Dimensional Bosons in Three-Dimensional Traps.” Physical Review Letters. American Physical Society, 2003. https://doi.org/10.1103/PhysRevLett.91.150401.","ista":"Lieb É, Seiringer R, Yngvason J. 2003. One-dimensional Bosons in three-dimensional traps. Physical Review Letters. 91(15), 1504011–1504014."},"status":"public","type":"journal_article","_id":"2358","date_created":"2018-12-11T11:57:12Z","doi":"10.1103/PhysRevLett.91.150401","date_published":"2003-10-10T00:00:00Z","issue":"15","volume":91,"page":"1504011 - 1504014","publication":"Physical Review Letters","day":"10","year":"2003","publication_status":"published","intvolume":" 91","month":"10","main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/cond-mat/0304071"}],"oa":1,"publisher":"American Physical Society","quality_controlled":0,"abstract":[{"text":"A study was conducted on the one-dimensional (1D) bosons in three-dimensional (3D) traps. A rigorous analysis was carried out on the parameter regions in which various types of 1D or 3D behavior occurred in the ground state. The four parameter regions include density, transverse, longitudinal dimensions and scattering length.","lang":"eng"}]},{"date_updated":"2021-01-12T06:57:20Z","citation":{"chicago":"Wagner, Uli. “On K-Sets and Their Applications.” ETH Zurich, 2003. https://doi.org/10.3929/ethz-a-004708408.","ista":"Wagner U. 2003. On k-Sets and Their Applications. ETH Zurich.","mla":"Wagner, Uli. On K-Sets and Their Applications. ETH Zurich, 2003, doi:10.3929/ethz-a-004708408.","ieee":"U. Wagner, “On k-Sets and Their Applications,” ETH Zurich, 2003.","short":"U. Wagner, On K-Sets and Their Applications, ETH Zurich, 2003.","apa":"Wagner, U. (2003). On k-Sets and Their Applications. ETH Zurich. https://doi.org/10.3929/ethz-a-004708408","ama":"Wagner U. On k-Sets and Their Applications. 2003. doi:10.3929/ethz-a-004708408"},"extern":1,"publist_id":"4511","author":[{"last_name":"Wagner","orcid":"0000-0002-1494-0568","full_name":"Uli Wagner","id":"36690CA2-F248-11E8-B48F-1D18A9856A87","first_name":"Uli"}],"title":"On k-Sets and Their Applications","_id":"2414","type":"dissertation","status":"public","year":"2003","publication_status":"published","day":"01","doi":"10.3929/ethz-a-004708408","date_published":"2003-01-01T00:00:00Z","date_created":"2018-12-11T11:57:31Z","publisher":"ETH Zurich","quality_controlled":0,"month":"01"},{"title":"Shape dimension and intrinsic metric from samples of manifolds with high co-dimension","publist_id":"4501","author":[{"full_name":"Giesen, Joachim","last_name":"Giesen","first_name":"Joachim"},{"first_name":"Uli","id":"36690CA2-F248-11E8-B48F-1D18A9856A87","last_name":"Wagner","orcid":"0000-0002-1494-0568","full_name":"Uli Wagner"}],"extern":1,"date_updated":"2021-01-12T06:57:24Z","citation":{"mla":"Giesen, Joachim, and Uli Wagner. Shape Dimension and Intrinsic Metric from Samples of Manifolds with High Co-Dimension. ACM, 2003, pp. 329–37, doi:10.1145/777792.777841.","ama":"Giesen J, Wagner U. Shape dimension and intrinsic metric from samples of manifolds with high co-dimension. In: ACM; 2003:329-337. doi:10.1145/777792.777841","apa":"Giesen, J., & Wagner, U. (2003). Shape dimension and intrinsic metric from samples of manifolds with high co-dimension (pp. 329–337). Presented at the SoCG: Symposium on Computational Geometry, ACM. https://doi.org/10.1145/777792.777841","ieee":"J. Giesen and U. Wagner, “Shape dimension and intrinsic metric from samples of manifolds with high co-dimension,” presented at the SoCG: Symposium on Computational Geometry, 2003, pp. 329–337.","short":"J. Giesen, U. Wagner, in:, ACM, 2003, pp. 329–337.","chicago":"Giesen, Joachim, and Uli Wagner. “Shape Dimension and Intrinsic Metric from Samples of Manifolds with High Co-Dimension,” 329–37. ACM, 2003. https://doi.org/10.1145/777792.777841.","ista":"Giesen J, Wagner U. 2003. Shape dimension and intrinsic metric from samples of manifolds with high co-dimension. SoCG: Symposium on Computational Geometry, 329–337."},"status":"public","conference":{"name":"SoCG: Symposium on Computational Geometry"},"type":"conference","_id":"2424","date_created":"2018-12-11T11:57:35Z","date_published":"2003-06-01T00:00:00Z","doi":"10.1145/777792.777841","page":"329 - 337","day":"01","year":"2003","publication_status":"published","month":"06","publisher":"ACM","quality_controlled":0,"abstract":[{"lang":"eng","text":"We introduce the adaptive neighborhood graph as a data structure for modeling a smooth manifold M embedded in some (potentially very high-dimensional) Euclidean space ℝd. We assume that M is known to us only through a finite sample P ⊂ M, as it is often the case in applications. The adaptive neighborhood graph is a geometric graph on P. Its complexity is at most min{2O(k)(n, n2}, where n = |P| and k = dim M, as opposed to the n⌈d/2⌉ complexity of the Delaunay triangulation, which is often used to model manifolds. We show that we can provably correctly infer the connectivity of M and the dimension of M from the adaptive neighborhood graph provided a certain standard sampling condition is fulfilled. The running time of the dimension detection algorithm is d2O(k7 log k) for each connected component of M. If the dimension is considered constant, this is a constant-time operation, and the adaptive neighborhood graph is of linear size. Moreover, the exponential dependence of the constants is only on the intrinsic dimension k, not on the ambient dimension d. This is of particular interest if the co-dimension is high, i.e., if k is much smaller than d, as is the case in many applications. The adaptive neighborhood graph also allows us to approximate the geodesic distances between the points in P."}]},{"month":"06","quality_controlled":0,"publisher":"ACM","abstract":[{"text":"A finite set N ⊃ Rd is a weak ε-net for an n-point set X ⊃ Rd (with respect to convex sets) if N intersects every convex set K with |K ∩ X| ≥ εn. We give an alternative, and arguably simpler, proof of the fact, first shown by Chazelle et al. [7], that every point set X in Rd admits a weak ε-net of cardinality O(ε-d polylog(1/ε)). Moreover, for a number of special point sets (e.g., for points on the moment curve), our method gives substantially better bounds. The construction yields an algorithm to construct such weak ε-nets in time O(n ln(1/ε)). We also prove, by a different method, a near-linear upper bound for points uniformly distributed on the (d - 1)-dimensional sphere.","lang":"eng"}],"date_created":"2018-12-11T11:57:34Z","doi":"10.1145/777792.777813","date_published":"2003-06-01T00:00:00Z","page":"129 - 135","day":"01","publication_status":"published","year":"2003","status":"public","conference":{"name":"SoCG: Symposium on Computational Geometry"},"type":"conference","_id":"2423","title":"New constructions of weak epsilon-nets","publist_id":"4502","author":[{"last_name":"Matoušek","full_name":"Matoušek, Jiří","first_name":"Jiří"},{"first_name":"Uli","id":"36690CA2-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-1494-0568","full_name":"Uli Wagner","last_name":"Wagner"}],"extern":1,"citation":{"ista":"Matoušek J, Wagner U. 2003. New constructions of weak epsilon-nets. SoCG: Symposium on Computational Geometry, 129–135.","chicago":"Matoušek, Jiří, and Uli Wagner. “New Constructions of Weak Epsilon-Nets,” 129–35. ACM, 2003. https://doi.org/10.1145/777792.777813.","apa":"Matoušek, J., & Wagner, U. (2003). New constructions of weak epsilon-nets (pp. 129–135). Presented at the SoCG: Symposium on Computational Geometry, ACM. https://doi.org/10.1145/777792.777813","ama":"Matoušek J, Wagner U. New constructions of weak epsilon-nets. In: ACM; 2003:129-135. doi:10.1145/777792.777813","ieee":"J. Matoušek and U. Wagner, “New constructions of weak epsilon-nets,” presented at the SoCG: Symposium on Computational Geometry, 2003, pp. 129–135.","short":"J. Matoušek, U. Wagner, in:, ACM, 2003, pp. 129–135.","mla":"Matoušek, Jiří, and Uli Wagner. New Constructions of Weak Epsilon-Nets. ACM, 2003, pp. 129–35, doi:10.1145/777792.777813."},"date_updated":"2021-01-12T06:57:24Z"},{"year":"2003","publication_status":"published","day":"01","page":"583 - 588","date_published":"2003-01-01T00:00:00Z","date_created":"2018-12-11T11:57:34Z","abstract":[{"text":"We prove a lower bound of 0.3288(4 n) for the rectilinear crossing number cr̄(Kn) of a complete graph on n vertices, or in other words, for the minimum number of convex quadrilaterals in any set of n points in general position in the Euclidean plane. As we see it, the main contribution of this paper is not so much the concrete numerical improvement over earlier bounds, as the novel method of proof, which is not based on bounding cr̄(Kn) for some small n.","lang":"eng"}],"publisher":"SIAM","quality_controlled":0,"main_file_link":[{"open_access":"0","url":"http://dl.acm.org/citation.cfm?id=644206"}],"month":"01","citation":{"chicago":"Wagner, Uli. “On the Rectilinear Crossing Number of Complete Graphs,” 583–88. SIAM, 2003.","ista":"Wagner U. 2003. On the rectilinear crossing number of complete graphs. SODA: Symposium on Discrete Algorithms, 583–588.","mla":"Wagner, Uli. On the Rectilinear Crossing Number of Complete Graphs. SIAM, 2003, pp. 583–88.","apa":"Wagner, U. (2003). On the rectilinear crossing number of complete graphs (pp. 583–588). Presented at the SODA: Symposium on Discrete Algorithms, SIAM.","ama":"Wagner U. On the rectilinear crossing number of complete graphs. In: SIAM; 2003:583-588.","short":"U. Wagner, in:, SIAM, 2003, pp. 583–588.","ieee":"U. Wagner, “On the rectilinear crossing number of complete graphs,” presented at the SODA: Symposium on Discrete Algorithms, 2003, pp. 583–588."},"date_updated":"2021-01-12T06:57:24Z","extern":1,"publist_id":"4503","author":[{"full_name":"Uli Wagner","orcid":"0000-0002-1494-0568","last_name":"Wagner","first_name":"Uli","id":"36690CA2-F248-11E8-B48F-1D18A9856A87"}],"title":"On the rectilinear crossing number of complete graphs","_id":"2422","type":"conference","conference":{"name":"SODA: Symposium on Discrete Algorithms"},"status":"public"},{"_id":"2623","type":"journal_article","status":"public","date_updated":"2021-01-12T06:58:39Z","citation":{"mla":"Coesmans, Michiel, et al. “Mechanisms Underlying Cerebellar Motor Deficits Due to MGluR1-Autoantibodies.” Annals of Neurology, vol. 53, no. 3, Wiley-Blackwell, 2003, pp. 325–36, doi:10.1002/ana.10451.","ama":"Coesmans M, Sillevis Smitt P, Linden D, et al. Mechanisms underlying cerebellar motor deficits due to mGluR1-autoantibodies. Annals of Neurology. 2003;53(3):325-336. doi:10.1002/ana.10451","apa":"Coesmans, M., Sillevis Smitt, P., Linden, D., Shigemoto, R., Hirano, T., Yamakawa, Y., … De Zeeuw, C. (2003). Mechanisms underlying cerebellar motor deficits due to mGluR1-autoantibodies. Annals of Neurology. Wiley-Blackwell. https://doi.org/10.1002/ana.10451","ieee":"M. Coesmans et al., “Mechanisms underlying cerebellar motor deficits due to mGluR1-autoantibodies,” Annals of Neurology, vol. 53, no. 3. Wiley-Blackwell, pp. 325–336, 2003.","short":"M. Coesmans, P. Sillevis Smitt, D. Linden, R. Shigemoto, T. Hirano, Y. Yamakawa, A. Van Alphen, C. Luo, J. Van Der Geest, J. Kros, C. Gaillard, M. Frens, C. De Zeeuw, Annals of Neurology 53 (2003) 325–336.","chicago":"Coesmans, Michiel, Peter Sillevis Smitt, David Linden, Ryuichi Shigemoto, Tomoo Hirano, Yoshinori Yamakawa, Adriaan Van Alphen, et al. “Mechanisms Underlying Cerebellar Motor Deficits Due to MGluR1-Autoantibodies.” Annals of Neurology. Wiley-Blackwell, 2003. https://doi.org/10.1002/ana.10451.","ista":"Coesmans M, Sillevis Smitt P, Linden D, Shigemoto R, Hirano T, Yamakawa Y, Van Alphen A, Luo C, Van Der Geest J, Kros J, Gaillard C, Frens M, De Zeeuw C. 2003. Mechanisms underlying cerebellar motor deficits due to mGluR1-autoantibodies. Annals of Neurology. 53(3), 325–336."},"extern":1,"publist_id":"4274","author":[{"full_name":"Coesmans, Michiel P","last_name":"Coesmans","first_name":"Michiel"},{"last_name":"Sillevis Smitt","full_name":"Sillevis-Smitt, Peter A","first_name":"Peter"},{"full_name":"Linden, David J","last_name":"Linden","first_name":"David"},{"last_name":"Shigemoto","orcid":"0000-0001-8761-9444","full_name":"Ryuichi Shigemoto","first_name":"Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Hirano, Tomoo","last_name":"Hirano","first_name":"Tomoo"},{"full_name":"Yamakawa, Yoshinori","last_name":"Yamakawa","first_name":"Yoshinori"},{"first_name":"Adriaan","full_name":"Van Alphen, Adriaan M","last_name":"Van Alphen"},{"first_name":"Chongde","full_name":"Luo, Chongde","last_name":"Luo"},{"last_name":"Van Der Geest","full_name":"Van Der Geest, Jos N","first_name":"Jos"},{"first_name":"Johan","full_name":"Kros, Johan M","last_name":"Kros"},{"last_name":"Gaillard","full_name":"Gaillard, Carlo A","first_name":"Carlo"},{"full_name":"Frens, Maarten A","last_name":"Frens","first_name":"Maarten"},{"first_name":"Chris","full_name":"De Zeeuw, Chris I","last_name":"De Zeeuw"}],"title":"Mechanisms underlying cerebellar motor deficits due to mGluR1-autoantibodies","abstract":[{"text":"Patients with Hodgkin's disease can develop paraneoplastic cerebellar ataxia because of the generation of autoantibodies against mGluR1 (mGluR1-Abs). Yet, the pathophysiological mechanisms underlying their motor coordination deficits remain to be elucidated. Here, we show that application of IgG purified from the patients' serum to cerebellar slices of mice acutely reduces the basal activity of Purkinje cells, whereas application to the flocculus of mice in vivo evokes acute disturbances in the performance of their compensatory eye movements. In addition, the mGluR1-Abs block induction of long-term depression in cultured mouse Purkinje cells, whereas the cerebellar motor learning behavior of the patients is affected in that they show impaired adaptation of their saccadic eye movements. Finally, postmortem analysis of the cerebellum of a paraneoplastic cerebellar ataxia patient showed that the number of Purkinje cells was significantly reduced by approximately two thirds compared with three controls. We conclude that autoantibodies against mGluR1 can cause cerebellar motor coordination deficits caused by a combination of rapid effects on both acute and plastic responses of Purkinje cells and chronic degenerative effects.","lang":"eng"}],"quality_controlled":0,"publisher":"Wiley-Blackwell","month":"03","intvolume":" 53","year":"2003","publication_status":"published","day":"01","publication":"Annals of Neurology","page":"325 - 336","volume":53,"issue":"3","doi":"10.1002/ana.10451","date_published":"2003-03-01T00:00:00Z","date_created":"2018-12-11T11:58:44Z"},{"publication":"European Journal of Neuroscience","day":"01","publication_status":"published","year":"2003","date_created":"2018-12-11T11:58:44Z","doi":"10.1046/j.1460-9568.2003.02499.x","volume":17,"date_published":"2003-03-01T00:00:00Z","issue":"5","page":"1023 - 1032","abstract":[{"text":"Metabotropic glutamate receptor 1 (mGluR1) plays a crucial role in synaptic plasticity and motor learning in the cerebellum. We have studied activity-dependent changes in mGluR1 function in mouse cultured Purkinje neurons. Depolarizing stimulation potentiated Ca2+ and current responses to an mGluR1 agonist for several hours in the cultured Purkinje neurons. It also blocked internalization of mGluR1 and increased the number of mGluR1s on the cell membrane. We found that depolarization simultaneously increased transcription of Homer1a in Purkinje neurons. Homer1a inhibited internalization and increased cell-surface expression of mGluR1 when coexpressed in human embryonic kidney (HEK)-293 cells. Depolarization-induced Homer1a expression in Purkinje neurons was blocked by a mitogen-activated protein kinase (MAPK) inhibitor. Changes in internalization and mGluR1-mediated Ca2+ response were also blocked by inhibition of MAPK activity, suggesting that localization and activity of mGluR1 were regulated in the same signalling pathway as Homer1a expression. It is thus suggested that depolarization of the Purkinje neuron leads to the increment in mGluR1 responsiveness through MAPK activity and induction of Homer1a expression, which increases active mGluR1 on the cell surface by blocking internalization of mGluR1.","lang":"eng"}],"intvolume":" 17","month":"03","quality_controlled":0,"publisher":"Wiley-Blackwell","extern":1,"citation":{"ama":"Minami I, Kengaku M, Smitt S, Shigemoto R, Hirano T. Long-term potentiation of mGluR1 activity by depolarization-induced Homer1a in mouse cerebellar Purkinje neurons. European Journal of Neuroscience. 2003;17(5):1023-1032. doi:10.1046/j.1460-9568.2003.02499.x","apa":"Minami, I., Kengaku, M., Smitt, S., Shigemoto, R., & Hirano, T. (2003). Long-term potentiation of mGluR1 activity by depolarization-induced Homer1a in mouse cerebellar Purkinje neurons. European Journal of Neuroscience. Wiley-Blackwell. https://doi.org/10.1046/j.1460-9568.2003.02499.x","short":"I. Minami, M. Kengaku, S. Smitt, R. Shigemoto, T. Hirano, European Journal of Neuroscience 17 (2003) 1023–1032.","ieee":"I. Minami, M. Kengaku, S. Smitt, R. Shigemoto, and T. Hirano, “Long-term potentiation of mGluR1 activity by depolarization-induced Homer1a in mouse cerebellar Purkinje neurons,” European Journal of Neuroscience, vol. 17, no. 5. Wiley-Blackwell, pp. 1023–1032, 2003.","mla":"Minami, Itsunari, et al. “Long-Term Potentiation of MGluR1 Activity by Depolarization-Induced Homer1a in Mouse Cerebellar Purkinje Neurons.” European Journal of Neuroscience, vol. 17, no. 5, Wiley-Blackwell, 2003, pp. 1023–32, doi:10.1046/j.1460-9568.2003.02499.x.","ista":"Minami I, Kengaku M, Smitt S, Shigemoto R, Hirano T. 2003. Long-term potentiation of mGluR1 activity by depolarization-induced Homer1a in mouse cerebellar Purkinje neurons. European Journal of Neuroscience. 17(5), 1023–1032.","chicago":"Minami, Itsunari, Mineko Kengaku, Sillevis Smitt, Ryuichi Shigemoto, and Tomoo Hirano. “Long-Term Potentiation of MGluR1 Activity by Depolarization-Induced Homer1a in Mouse Cerebellar Purkinje Neurons.” European Journal of Neuroscience. Wiley-Blackwell, 2003. https://doi.org/10.1046/j.1460-9568.2003.02499.x."},"date_updated":"2021-01-12T06:58:39Z","title":"Long-term potentiation of mGluR1 activity by depolarization-induced Homer1a in mouse cerebellar Purkinje neurons","author":[{"first_name":"Itsunari","last_name":"Minami","full_name":"Minami, Itsunari"},{"full_name":"Kengaku, Mineko","last_name":"Kengaku","first_name":"Mineko"},{"first_name":"Sillevis","full_name":"Smitt, Sillevis P","last_name":"Smitt"},{"full_name":"Ryuichi Shigemoto","orcid":"0000-0001-8761-9444","last_name":"Shigemoto","first_name":"Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Tomoo","full_name":"Hirano, Tomoo","last_name":"Hirano"}],"publist_id":"4273","_id":"2625","status":"public","type":"journal_article"},{"publication":"Neuroreport","day":"01","publication_status":"published","year":"2003","date_created":"2018-12-11T11:58:45Z","doi":"10.1097/01.wnr.0000074344.81633.e4","date_published":"2003-05-01T00:00:00Z","issue":"7","volume":14,"page":"947 - 950","abstract":[{"lang":"eng","text":"The expression pattern of metabotropic glutamate receptor Iα (mGluR1α) was immunohistochemically investigated in substantia nigra dopaminergic neurons of the macaque monkey. In normal monkeys, mGluR1α immunoreactivity was weakly observed in the dorsal tier of the substantia nigra pars compacta (SNc-d) where calbindin-D28k-containing dopaminergic neurons invulnerable to parkinsonian degeneration are specifically located. On the other hand, mGluR1α was strongly expressed in the ventral tier of the substantia nigra pars cornpacta (SNc-v). In monkeys treated with the parkinsonism-inducing drug, I-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), mGluR1α expression was decreased in dopaminergic neurons in the SNc-v that were spared its toxic action. These results suggest that mGluR1α expression may be involved at least partly in the vulnerability of dopaminergic neurons to parkinsonian insults."}],"intvolume":" 14","month":"05","publisher":"Lippincott, Williams & Wilkins","quality_controlled":0,"extern":1,"citation":{"ieee":"K. Kaneda, M. Imanishi, A. Nambu, R. Shigemoto, and M. Takada, “Differential expression patterns of mGluR1α in monkey nigral dopamine neurons,” Neuroreport, vol. 14, no. 7. Lippincott, Williams & Wilkins, pp. 947–950, 2003.","short":"K. Kaneda, M. Imanishi, A. Nambu, R. Shigemoto, M. Takada, Neuroreport 14 (2003) 947–950.","ama":"Kaneda K, Imanishi M, Nambu A, Shigemoto R, Takada M. Differential expression patterns of mGluR1α in monkey nigral dopamine neurons. Neuroreport. 2003;14(7):947-950. doi:10.1097/01.wnr.0000074344.81633.e4","apa":"Kaneda, K., Imanishi, M., Nambu, A., Shigemoto, R., & Takada, M. (2003). Differential expression patterns of mGluR1α in monkey nigral dopamine neurons. Neuroreport. Lippincott, Williams & Wilkins. https://doi.org/10.1097/01.wnr.0000074344.81633.e4","mla":"Kaneda, Katsuyuki, et al. “Differential Expression Patterns of MGluR1α in Monkey Nigral Dopamine Neurons.” Neuroreport, vol. 14, no. 7, Lippincott, Williams & Wilkins, 2003, pp. 947–50, doi:10.1097/01.wnr.0000074344.81633.e4.","ista":"Kaneda K, Imanishi M, Nambu A, Shigemoto R, Takada M. 2003. Differential expression patterns of mGluR1α in monkey nigral dopamine neurons. Neuroreport. 14(7), 947–950.","chicago":"Kaneda, Katsuyuki, Michiko Imanishi, Atsushi Nambu, Ryuichi Shigemoto, and Masahiko Takada. “Differential Expression Patterns of MGluR1α in Monkey Nigral Dopamine Neurons.” Neuroreport. Lippincott, Williams & Wilkins, 2003. https://doi.org/10.1097/01.wnr.0000074344.81633.e4."},"date_updated":"2021-01-12T06:58:40Z","title":"Differential expression patterns of mGluR1α in monkey nigral dopamine neurons","publist_id":"4272","author":[{"first_name":"Katsuyuki","last_name":"Kaneda","full_name":"Kaneda, Katsuyuki"},{"last_name":"Imanishi","full_name":"Imanishi, Michiko","first_name":"Michiko"},{"first_name":"Atsushi","last_name":"Nambu","full_name":"Nambu, Atsushi"},{"first_name":"Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","full_name":"Ryuichi Shigemoto","orcid":"0000-0001-8761-9444","last_name":"Shigemoto"},{"first_name":"Masahiko","last_name":"Takada","full_name":"Takada, Masahiko"}],"_id":"2626","status":"public","type":"journal_article"},{"type":"journal_article","status":"public","_id":"2627","publist_id":"4271","author":[{"last_name":"Kawakami","full_name":"Kawakami, Ryosuke","first_name":"Ryosuke"},{"first_name":"Yoshiaki","last_name":"Shinohara","full_name":"Shinohara, Yoshiaki"},{"full_name":"Kato, Yuichiro","last_name":"Kato","first_name":"Yuichiro"},{"first_name":"Hiroyuki","full_name":"Sugiyama, Hiroyuki","last_name":"Sugiyama"},{"id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","first_name":"Ryuichi","last_name":"Shigemoto","full_name":"Ryuichi Shigemoto","orcid":"0000-0001-8761-9444"},{"first_name":"Isao","last_name":"Ito","full_name":"Ito, Isao"}],"title":"Asymmetrical allocation of NMDA receptor ε2 subunits in hippocampal circuitry","date_updated":"2021-01-12T06:58:40Z","citation":{"short":"R. Kawakami, Y. Shinohara, Y. Kato, H. Sugiyama, R. Shigemoto, I. Ito, Science 300 (2003) 990–994.","ieee":"R. Kawakami, Y. Shinohara, Y. Kato, H. Sugiyama, R. Shigemoto, and I. Ito, “Asymmetrical allocation of NMDA receptor ε2 subunits in hippocampal circuitry,” Science, vol. 300, no. 5621. American Association for the Advancement of Science, pp. 990–994, 2003.","ama":"Kawakami R, Shinohara Y, Kato Y, Sugiyama H, Shigemoto R, Ito I. Asymmetrical allocation of NMDA receptor ε2 subunits in hippocampal circuitry. Science. 2003;300(5621):990-994. doi:10.1126/science.1082609","apa":"Kawakami, R., Shinohara, Y., Kato, Y., Sugiyama, H., Shigemoto, R., & Ito, I. (2003). Asymmetrical allocation of NMDA receptor ε2 subunits in hippocampal circuitry. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1082609","mla":"Kawakami, Ryosuke, et al. “Asymmetrical Allocation of NMDA Receptor Ε2 Subunits in Hippocampal Circuitry.” Science, vol. 300, no. 5621, American Association for the Advancement of Science, 2003, pp. 990–94, doi:10.1126/science.1082609.","ista":"Kawakami R, Shinohara Y, Kato Y, Sugiyama H, Shigemoto R, Ito I. 2003. Asymmetrical allocation of NMDA receptor ε2 subunits in hippocampal circuitry. Science. 300(5621), 990–994.","chicago":"Kawakami, Ryosuke, Yoshiaki Shinohara, Yuichiro Kato, Hiroyuki Sugiyama, Ryuichi Shigemoto, and Isao Ito. “Asymmetrical Allocation of NMDA Receptor Ε2 Subunits in Hippocampal Circuitry.” Science. American Association for the Advancement of Science, 2003. https://doi.org/10.1126/science.1082609."},"extern":1,"quality_controlled":0,"publisher":"American Association for the Advancement of Science","intvolume":" 300","month":"05","abstract":[{"lang":"eng","text":"Despite its implications for higher order functions of the brain, little is currently known about the molecular basis of left-right asymmetry of the brain. Here we report that synaptic distribution of N-methyl-D-aspartate (NMDA) receptor GluRε2 (NR2B) subunits in the adult mouse hippocampus is asymmetrical between the left and right and between the apical and basal dendrites of single neurons. These asymmetrical allocations of ε2 subunits differentiate the properties of NMDA receptors and synaptic plasticity between the left and right hippocampus. These results provide a molecular basis for the structural and functional asymmetry of the mature brain."}],"page":"990 - 994","date_created":"2018-12-11T11:58:45Z","issue":"5621","volume":300,"date_published":"2003-05-09T00:00:00Z","doi":"10.1126/science.1082609","publication_status":"published","year":"2003","publication":"Science","day":"09"},{"day":"01","publication":"European Journal of Neuroscience","year":"2003","publication_status":"published","volume":17,"date_published":"2003-06-01T00:00:00Z","doi":"10.1046/j.1460-9568.2003.02697.x","issue":"12","date_created":"2018-12-11T11:58:46Z","page":"2503 - 2520","abstract":[{"text":"The release of neurotransmitters is modulated by presynaptic metabotropic glutamate receptors (mGluRs), which show a highly selective expression and subcellular location in glutamatergic terminals in the hippocampus. Using immunocytochemistry, we investigated whether one of the receptors, mGluR7, whose level of expression is governed by the postsynaptic target, was present in GABAergic terminals and whether such terminals targeted particular cells. A total of 165 interneuron dendritic profiles receiving 466 synapses (82% mGluR7a-positive) were analysed. The presynaptic active zones of most GAD-(77%) or GABA-positive (94%) synaptic boutons on interneurons innervated by mGluR7a-enriched glutamatergic terminals (mGluR7a-decorated) were immunopositive for mGluR7a. GABAergic terminals on pyramidal cells and most other interneurons in str. oriens were mGluR7a-immunonegative. The mGluR7a-decorated cells were mostly somatostatin- and mGluR1α-immunopositive neurons in str. oriens and the alveus. Their GABAergic input mainly originated from VIP-positive terminals, 90% of which expressed high levels of mGluR7a in the presynaptic active zone. Parvalbumin-positive synaptic terminals were rare on mGluR7a-decorated cells, but on these neurons 73% of them were mGluR7a-immunopositive. Some type II synapses innervating interneurons were immunopositive for mGluR7b, as were some type I synapses. Because not all target cells of VIP-positive neurons are known it has not been possible to determine whether mGluR7 is expressed in a target-cell-specific manner in the terminals of single GABAergic cells. The activation of mGluR7 may decrease GABA release to mGluR7-decorated cells at times of high pyramidal cell activity, which elevates extracellular glutamate levels. Alternatively, the presynaptic receptor may be activated by as yet unidentified endogenous ligands released by the GABAergic terminals or the postsynaptic dendrites.","lang":"eng"}],"month":"06","intvolume":" 17","publisher":"Wiley-Blackwell","quality_controlled":0,"extern":1,"date_updated":"2021-01-12T06:58:41Z","citation":{"mla":"Somogyi, Péter, et al. “High Level of MGluR7 in the Presynaptic Active Zones of Select Populations of GABAergic Terminals Innervating Interneurons in the Rat Hippocampus.” European Journal of Neuroscience, vol. 17, no. 12, Wiley-Blackwell, 2003, pp. 2503–20, doi:10.1046/j.1460-9568.2003.02697.x.","ama":"Somogyi P, Dalezios Y, Luján R, Roberts J, Watanabe M, Shigemoto R. High level of mGluR7 in the presynaptic active zones of select populations of GABAergic terminals innervating interneurons in the rat hippocampus. European Journal of Neuroscience. 2003;17(12):2503-2520. doi:10.1046/j.1460-9568.2003.02697.x","apa":"Somogyi, P., Dalezios, Y., Luján, R., Roberts, J., Watanabe, M., & Shigemoto, R. (2003). High level of mGluR7 in the presynaptic active zones of select populations of GABAergic terminals innervating interneurons in the rat hippocampus. European Journal of Neuroscience. Wiley-Blackwell. https://doi.org/10.1046/j.1460-9568.2003.02697.x","ieee":"P. Somogyi, Y. Dalezios, R. Luján, J. Roberts, M. Watanabe, and R. Shigemoto, “High level of mGluR7 in the presynaptic active zones of select populations of GABAergic terminals innervating interneurons in the rat hippocampus,” European Journal of Neuroscience, vol. 17, no. 12. Wiley-Blackwell, pp. 2503–2520, 2003.","short":"P. Somogyi, Y. Dalezios, R. Luján, J. Roberts, M. Watanabe, R. Shigemoto, European Journal of Neuroscience 17 (2003) 2503–2520.","chicago":"Somogyi, Péter, Yannis Dalezios, Rafael Luján, John Roberts, Masahiko Watanabe, and Ryuichi Shigemoto. “High Level of MGluR7 in the Presynaptic Active Zones of Select Populations of GABAergic Terminals Innervating Interneurons in the Rat Hippocampus.” European Journal of Neuroscience. Wiley-Blackwell, 2003. https://doi.org/10.1046/j.1460-9568.2003.02697.x.","ista":"Somogyi P, Dalezios Y, Luján R, Roberts J, Watanabe M, Shigemoto R. 2003. High level of mGluR7 in the presynaptic active zones of select populations of GABAergic terminals innervating interneurons in the rat hippocampus. European Journal of Neuroscience. 17(12), 2503–2520."},"title":"High level of mGluR7 in the presynaptic active zones of select populations of GABAergic terminals innervating interneurons in the rat hippocampus","author":[{"full_name":"Somogyi, Péter","last_name":"Somogyi","first_name":"Péter"},{"first_name":"Yannis","full_name":"Dalezios, Yannis","last_name":"Dalezios"},{"last_name":"Luján","full_name":"Luján, Rafael","first_name":"Rafael"},{"full_name":"Roberts, John D","last_name":"Roberts","first_name":"John"},{"last_name":"Watanabe","full_name":"Watanabe, Masahiko","first_name":"Masahiko"},{"orcid":"0000-0001-8761-9444","full_name":"Ryuichi Shigemoto","last_name":"Shigemoto","first_name":"Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87"}],"publist_id":"4269","_id":"2629","status":"public","type":"journal_article"},{"publication":"Journal of Physiology","day":"15","publication_status":"published","year":"2003","date_created":"2018-12-11T11:58:45Z","volume":549,"date_published":"2003-05-15T00:00:00Z","issue":"1","doi":"10.1113/jphysiol.2002.033472","page":"75 - 92","abstract":[{"text":"We aimed to estimate the number of AMPA receptors (AMPARs) bound by the quantal transmitter packet, their single-channel conductance and their density in the postsynaptic membrane at cerebellar Purkinje cell synapses. The synaptic and extrasynaptic AMPARs were examined in Purkinje cells in 2- to 4-day-old rats, when they receive synaptic inputs solely from climbing fibres (CFs). Evoked CF EPSCs and whole-cell AMPA currents displayed roughly linear current-voltage relationships, consistent with the presence of GluR2 subunits in synaptic and extrasynaptic AMPARs. The mean quantal size, estimated from the miniature EPSCs (MEPSCs), was ∼300 pS. Peak-scaled non-stationary fluctuation analysis of spontaneous EPSCs and MEPSCs gave a weighted-mean synaptic channel conductance of ∼5 pS (∼7 pS when corrected for filtering). By applying non-stationary fluctuation analysis to extrasynaptic currents activated by brief glutamate pulses (5 mM), we also obtained a small single-channel conductance estimate for extrasynaptic AMPARs (∼11 pS). This approach allowed us to obtain a maximum open probability (Po,max) value for the extrasynaptic receptors (Po,max = 0.72). Directly resolved extrasynaptic channel openings in the continued presence of glutamate exhibited clear multiple-conductance levels. The mean area of the postsynaptic density (PSD) of these synapses was 0.074 μm2, measured by reconstructing electron-microscopic (EM) serial sections. Postembedding immunogold labelling by anti-GluR2/3 antibody revealed that AMPARs are localised in PSDs. From these data and by simulating error factors, we estimate that at least 66 AMPARs are bound by a quantal transmitter packet at CF-Purkinje cell synapses, and the receptors are packed at a minimum density of ∼900 μm-2 in the postsynaptic membrane.","lang":"eng"}],"intvolume":" 549","month":"05","publisher":"Wiley-Blackwell","quality_controlled":0,"extern":1,"citation":{"mla":"Momiyama, Akiko, et al. “The Density of AMPA Receptors Activated by a Transmitter Quantum at the Climbing Fibre - Purkinje Cell Synapse in Immature Rats.” Journal of Physiology, vol. 549, no. 1, Wiley-Blackwell, 2003, pp. 75–92, doi:10.1113/jphysiol.2002.033472.","apa":"Momiyama, A., Silver, R., Häusser, M., Notomi, T., Wu, Y., Shigemoto, R., & Cull Candy, S. (2003). The density of AMPA receptors activated by a transmitter quantum at the climbing fibre - Purkinje cell synapse in immature rats. Journal of Physiology. Wiley-Blackwell. https://doi.org/10.1113/jphysiol.2002.033472","ama":"Momiyama A, Silver R, Häusser M, et al. The density of AMPA receptors activated by a transmitter quantum at the climbing fibre - Purkinje cell synapse in immature rats. Journal of Physiology. 2003;549(1):75-92. doi:10.1113/jphysiol.2002.033472","short":"A. Momiyama, R. Silver, M. Häusser, T. Notomi, Y. Wu, R. Shigemoto, S. Cull Candy, Journal of Physiology 549 (2003) 75–92.","ieee":"A. Momiyama et al., “The density of AMPA receptors activated by a transmitter quantum at the climbing fibre - Purkinje cell synapse in immature rats,” Journal of Physiology, vol. 549, no. 1. Wiley-Blackwell, pp. 75–92, 2003.","chicago":"Momiyama, Akiko, Rachel Silver, Michael Häusser, Takuya Notomi, Yue Wu, Ryuichi Shigemoto, and Stuart Cull Candy. “The Density of AMPA Receptors Activated by a Transmitter Quantum at the Climbing Fibre - Purkinje Cell Synapse in Immature Rats.” Journal of Physiology. Wiley-Blackwell, 2003. https://doi.org/10.1113/jphysiol.2002.033472.","ista":"Momiyama A, Silver R, Häusser M, Notomi T, Wu Y, Shigemoto R, Cull Candy S. 2003. The density of AMPA receptors activated by a transmitter quantum at the climbing fibre - Purkinje cell synapse in immature rats. Journal of Physiology. 549(1), 75–92."},"date_updated":"2021-01-12T06:58:40Z","title":"The density of AMPA receptors activated by a transmitter quantum at the climbing fibre - Purkinje cell synapse in immature rats","author":[{"first_name":"Akiko","last_name":"Momiyama","full_name":"Momiyama, Akiko"},{"first_name":"Rachel","last_name":"Silver","full_name":"Silver, Rachel A"},{"last_name":"Häusser","full_name":"Häusser, Michael A","first_name":"Michael"},{"first_name":"Takuya","last_name":"Notomi","full_name":"Notomi, Takuya"},{"first_name":"Yue","full_name":"Wu, Yue","last_name":"Wu"},{"first_name":"Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8761-9444","full_name":"Ryuichi Shigemoto","last_name":"Shigemoto"},{"full_name":"Cull-Candy, Stuart G","last_name":"Cull Candy","first_name":"Stuart"}],"publist_id":"4270","_id":"2628","status":"public","type":"journal_article"},{"publication":"Journal of Neurochemistry","day":"01","publication_status":"published","year":"2003","date_created":"2018-12-11T11:58:46Z","doi":"10.1046/j.1471-4159.2003.01751.x","date_published":"2003-06-01T00:00:00Z","issue":"5","volume":85,"page":"1148 - 1158","abstract":[{"text":"Cyclic ADP-ribose (cADP-ribose) is a putative second messenger or modulator. However, the role of cADP-ribose in the downstream signals of the metabotropic glutamate receptors (mGluRs) is unclear. Here, we show that glutamate stimulates ADP-ribosyl cyclase activity in rat or mouse crude membranes of retina via group III mGluRs or in superior cervical ganglion via group I mGluRs. The retina of mGluR6-deficient mice showed no increase in the ADP-ribosyl cyclase level in response to glutamate. GTP enhanced the initial rate of basal and glutamate-stimulated cyclase activity. GTP-γ-S also stimulated basal activity. To determine whether the coupling mode of mGluRs to ADP-ribosyl cyclase is a feature common to individual cloned mGluRs, we expressed each mGluR subtype in NG108-15 neuroblastoma x glioma hybrid cells. The glutamate-induced stimulation of the cyclase occurs preferentially in NG108-15 cells over-expressing mGluRs1, 3, 5, and 6. Cells expressing mGluR2 or mGluRs4 and 7 exhibit inhibition or no coupling, respectively. Glutamate-induced activation or inhibition of the cyclase activity was eliminated after pre-treatment with cholera or pertussis toxin, respectively. Thus, the subtype-specific coupling of mGluRs to ADP-ribosyl cyclase via G proteins suggests that some glutamate-evoked neuronal functions are mediated by cADP-ribose.","lang":"eng"}],"intvolume":" 85","month":"06","publisher":"Wiley-Blackwell","quality_controlled":0,"extern":1,"citation":{"apa":"Higashida, H., Zhang, J., Mochida, S., Chen, X., Shin, Y., Noda, M., … Yokoyama, S. (2003). Subtype-specific coupling with ADP-ribosyl cyclase of metabotropic glutamate receptors in retina, cervical superior ganglion and NG108-15 cells. Journal of Neurochemistry. Wiley-Blackwell. https://doi.org/10.1046/j.1471-4159.2003.01751.x","ama":"Higashida H, Zhang J, Mochida S, et al. Subtype-specific coupling with ADP-ribosyl cyclase of metabotropic glutamate receptors in retina, cervical superior ganglion and NG108-15 cells. Journal of Neurochemistry. 2003;85(5):1148-1158. doi:10.1046/j.1471-4159.2003.01751.x","short":"H. Higashida, J. Zhang, S. Mochida, X. Chen, Y. Shin, M. Noda, K. Hossain, N. Hoshi, M. Hashii, R. Shigemoto, S. Nakanishi, Y. Fukuda, S. Yokoyama, Journal of Neurochemistry 85 (2003) 1148–1158.","ieee":"H. Higashida et al., “Subtype-specific coupling with ADP-ribosyl cyclase of metabotropic glutamate receptors in retina, cervical superior ganglion and NG108-15 cells,” Journal of Neurochemistry, vol. 85, no. 5. Wiley-Blackwell, pp. 1148–1158, 2003.","mla":"Higashida, Haruhiro, et al. “Subtype-Specific Coupling with ADP-Ribosyl Cyclase of Metabotropic Glutamate Receptors in Retina, Cervical Superior Ganglion and NG108-15 Cells.” Journal of Neurochemistry, vol. 85, no. 5, Wiley-Blackwell, 2003, pp. 1148–58, doi:10.1046/j.1471-4159.2003.01751.x.","ista":"Higashida H, Zhang J, Mochida S, Chen X, Shin Y, Noda M, Hossain K, Hoshi N, Hashii M, Shigemoto R, Nakanishi S, Fukuda Y, Yokoyama S. 2003. Subtype-specific coupling with ADP-ribosyl cyclase of metabotropic glutamate receptors in retina, cervical superior ganglion and NG108-15 cells. Journal of Neurochemistry. 85(5), 1148–1158.","chicago":"Higashida, Haruhiro, Jia Zhang, Sumiko Mochida, Xiao Chen, Yeonsook Shin, Mami Noda, Kazi Hossain, et al. “Subtype-Specific Coupling with ADP-Ribosyl Cyclase of Metabotropic Glutamate Receptors in Retina, Cervical Superior Ganglion and NG108-15 Cells.” Journal of Neurochemistry. Wiley-Blackwell, 2003. https://doi.org/10.1046/j.1471-4159.2003.01751.x."},"date_updated":"2021-01-12T06:58:42Z","title":"Subtype-specific coupling with ADP-ribosyl cyclase of metabotropic glutamate receptors in retina, cervical superior ganglion and NG108-15 cells","author":[{"last_name":"Higashida","full_name":"Higashida, Haruhiro","first_name":"Haruhiro"},{"full_name":"Zhang, Jia-Sheng","last_name":"Zhang","first_name":"Jia"},{"first_name":"Sumiko","last_name":"Mochida","full_name":"Mochida, Sumiko"},{"full_name":"Chen, Xiao-Liang","last_name":"Chen","first_name":"Xiao"},{"first_name":"Yeonsook","full_name":"Shin, Yeonsook","last_name":"Shin"},{"first_name":"Mami","last_name":"Noda","full_name":"Noda, Mami"},{"full_name":"Hossain, Kazi Z","last_name":"Hossain","first_name":"Kazi"},{"first_name":"Naoto","full_name":"Hoshi, Naoto","last_name":"Hoshi"},{"first_name":"Minako","last_name":"Hashii","full_name":"Hashii, Minako"},{"first_name":"Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","full_name":"Ryuichi Shigemoto","orcid":"0000-0001-8761-9444","last_name":"Shigemoto"},{"first_name":"Shigetada","last_name":"Nakanishi","full_name":"Nakanishi, Shigetada"},{"first_name":"Yutaka","full_name":"Fukuda, Yutaka","last_name":"Fukuda"},{"last_name":"Yokoyama","full_name":"Yokoyama, Shigeru","first_name":"Shigeru"}],"publist_id":"4268","_id":"2631","status":"public","type":"journal_article"},{"abstract":[{"text":"The modulation of calcium channels by metabotropic glutamate receptors (mGluRs) is a key event in the fine-tuning of neurotransmitter release. Here we report that, in cerebrocortical nerve terminals of adult rats, the inhibition of glutamate release is mediated by mGluR7. In this preparation, the major component of glutamate release is supported by P/Q-type Ca2+ channels (72.7%). However, mGluR7 selectively reduced the release component that is associated with N-type Ca2+ channels (29.9%). Inhibition of P/Q channels by mGluR7 is not masked by the higher efficiency of these channels in driving glutamate release when compared with N-type channels. Thus, activation of mGluR7 failed to reduce the release associated with P/Q channels when the extracellular calcium concentration, ([Ca2+]o), was reduced from 1.3 to 0.5 mM. Through Ca2+ imaging, we show that Ca2+ channels are distributed in a heterogeneous manner in individual nerve terminals. Indeed, in this preparation, nerve terminals were observed that contain N-type (31.1%; conotoxin GVIA-sensitive) or P/Q-type (64.3%; agatoxin IVA-sensitive) channels or that were insensitive to these two toxins (4.6%). Interestingly, the great majority of the responses to L-AP4 (95.4%) were observed in nerve terminals containing N-type channels. This specific co-localization of mGluR7 and N-type Ca2+-channels could explain the failure of the receptor to inhibit the P/Q channel-associated release component and also reveal the existence of specific targeting mechanisms to localize the two proteins in the same nerve terminal subset.","lang":"eng"}],"month":"07","intvolume":" 278","publisher":"American Society for Biochemistry and Molecular Biology","quality_controlled":0,"day":"27","publication":"Journal of Biological Chemistry","publication_status":"published","year":"2003","volume":278,"date_published":"2003-07-27T00:00:00Z","doi":"10.1074/jbc.M211471200","issue":"26","date_created":"2018-12-11T11:58:47Z","page":"23955 - 23962","_id":"2633","status":"public","type":"journal_article","extern":1,"citation":{"chicago":"Millán, Carmelo, Enrique Castro, Magdalena Torres, Ryuichi Shigemoto, and José Sánchez Prieto. “Co-Expression of Metabotropic Glutamate Receptor 7 and N-Type Ca2+ Channels in Single Cerebrocortical Nerve Terminals of Adult Rats.” Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology, 2003. https://doi.org/10.1074/jbc.M211471200.","ista":"Millán C, Castro E, Torres M, Shigemoto R, Sánchez Prieto J. 2003. Co-expression of metabotropic glutamate receptor 7 and N-type Ca2+ channels in single cerebrocortical nerve terminals of adult rats. Journal of Biological Chemistry. 278(26), 23955–23962.","mla":"Millán, Carmelo, et al. “Co-Expression of Metabotropic Glutamate Receptor 7 and N-Type Ca2+ Channels in Single Cerebrocortical Nerve Terminals of Adult Rats.” Journal of Biological Chemistry, vol. 278, no. 26, American Society for Biochemistry and Molecular Biology, 2003, pp. 23955–62, doi:10.1074/jbc.M211471200.","short":"C. Millán, E. Castro, M. Torres, R. Shigemoto, J. Sánchez Prieto, Journal of Biological Chemistry 278 (2003) 23955–23962.","ieee":"C. Millán, E. Castro, M. Torres, R. Shigemoto, and J. Sánchez Prieto, “Co-expression of metabotropic glutamate receptor 7 and N-type Ca2+ channels in single cerebrocortical nerve terminals of adult rats,” Journal of Biological Chemistry, vol. 278, no. 26. American Society for Biochemistry and Molecular Biology, pp. 23955–23962, 2003.","ama":"Millán C, Castro E, Torres M, Shigemoto R, Sánchez Prieto J. Co-expression of metabotropic glutamate receptor 7 and N-type Ca2+ channels in single cerebrocortical nerve terminals of adult rats. Journal of Biological Chemistry. 2003;278(26):23955-23962. doi:10.1074/jbc.M211471200","apa":"Millán, C., Castro, E., Torres, M., Shigemoto, R., & Sánchez Prieto, J. (2003). Co-expression of metabotropic glutamate receptor 7 and N-type Ca2+ channels in single cerebrocortical nerve terminals of adult rats. Journal of Biological Chemistry. American Society for Biochemistry and Molecular Biology. https://doi.org/10.1074/jbc.M211471200"},"date_updated":"2021-01-12T06:58:42Z","title":"Co-expression of metabotropic glutamate receptor 7 and N-type Ca2+ channels in single cerebrocortical nerve terminals of adult rats","publist_id":"4265","author":[{"first_name":"Carmelo","last_name":"Millán","full_name":"Millán, Carmelo"},{"last_name":"Castro","full_name":"Castro, Enrique G","first_name":"Enrique"},{"first_name":"Magdalena","full_name":"Torres, Magdalena","last_name":"Torres"},{"id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","first_name":"Ryuichi","last_name":"Shigemoto","orcid":"0000-0001-8761-9444","full_name":"Ryuichi Shigemoto"},{"first_name":"José","last_name":"Sánchez Prieto","full_name":"Sánchez-Prieto, José"}]},{"date_updated":"2021-01-12T06:58:42Z","citation":{"mla":"Holderith, Noémi, et al. “Cell Type-Dependent Expression of HCN1 in the Main Olfactory Bulb.” European Journal of Neuroscience, vol. 18, no. 2, Wiley-Blackwell, 2003, pp. 344–54, doi:10.1046/j.1460-9568.2003.02756.x.","ama":"Holderith N, Shigemoto R, Nusser Z. Cell type-dependent expression of HCN1 in the main olfactory bulb. European Journal of Neuroscience. 2003;18(2):344-354. doi:10.1046/j.1460-9568.2003.02756.x","apa":"Holderith, N., Shigemoto, R., & Nusser, Z. (2003). Cell type-dependent expression of HCN1 in the main olfactory bulb. European Journal of Neuroscience. Wiley-Blackwell. https://doi.org/10.1046/j.1460-9568.2003.02756.x","ieee":"N. Holderith, R. Shigemoto, and Z. Nusser, “Cell type-dependent expression of HCN1 in the main olfactory bulb,” European Journal of Neuroscience, vol. 18, no. 2. Wiley-Blackwell, pp. 344–354, 2003.","short":"N. Holderith, R. Shigemoto, Z. Nusser, European Journal of Neuroscience 18 (2003) 344–354.","chicago":"Holderith, Noémi, Ryuichi Shigemoto, and Zoltán Nusser. “Cell Type-Dependent Expression of HCN1 in the Main Olfactory Bulb.” European Journal of Neuroscience. Wiley-Blackwell, 2003. https://doi.org/10.1046/j.1460-9568.2003.02756.x.","ista":"Holderith N, Shigemoto R, Nusser Z. 2003. Cell type-dependent expression of HCN1 in the main olfactory bulb. European Journal of Neuroscience. 18(2), 344–354."},"extern":1,"author":[{"first_name":"Noémi","last_name":"Holderith","full_name":"Holderith, Noémi B"},{"id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","first_name":"Ryuichi","last_name":"Shigemoto","orcid":"0000-0001-8761-9444","full_name":"Ryuichi Shigemoto"},{"first_name":"Zoltán","full_name":"Nusser, Zoltán","last_name":"Nusser"}],"publist_id":"4266","title":"Cell type-dependent expression of HCN1 in the main olfactory bulb","_id":"2632","type":"journal_article","status":"public","publication_status":"published","year":"2003","publication":"European Journal of Neuroscience","day":"01","page":"344 - 354","date_created":"2018-12-11T11:58:47Z","issue":"2","date_published":"2003-07-01T00:00:00Z","volume":18,"doi":"10.1046/j.1460-9568.2003.02756.x","abstract":[{"lang":"eng","text":"In many brain regions, hyperpolarization-activated cationic currents (Ih) are involved in the generation of rhythmic activities, but the role of Ih in olfactory oscillations remains unclear. Knowledge of the cellular and subcellular distributions of hyperpolarization-activated and cyclic nucleotide-gated channel (HCN) subunits is necessary for understanding the role of Ih in olfactory network activities. Using light microscopic immunocytochemistry, we demonstrate strong HCN1 labelling of the glomerular layer and moderate staining of granule cell, internal and external plexiform layers of the rat main olfactory bulb. In the glomerular layer, among many unlabelled neurons, two distinct subpopulations of juxtaglomerular cells are labelled. Approximately 10% of the juxtaglomerular cells strongly express HCN1. These small diameter cells are immunoreactive for GABA and comprise a subpopulation of periglomerular cells. An additional subset of juxtaglomerular cells (≈ 1%) expresses low levels of HCN1. They are large in diameter, GABA immunonegative but immunopositive for vesicular glutamate transporter 2, characterizing them as external tufted cells. Quantitative immunogold localization revealed that the somatic plasma membranes of periglomerular cells contain approximately four times more HCN1 labelling than those of external tufted cells. Unlike in cortical pyramidal cells, immunogold density for HCN1 does not significantly differ in somatic and dendritic plasma membranes of external tufted cells, indicating that post-synaptic potentials arriving at proximal and distal dendrites are modulated by the same density of I h. Our results demonstrate a cell type-dependent expression of HCN1 in the olfactory bulb and predict a differential contribution of distinct juxtaglomerular cell types to network oscillations."}],"publisher":"Wiley-Blackwell","quality_controlled":0,"intvolume":" 18","month":"07"},{"volume":23,"issue":"35","date_published":"2003-12-03T00:00:00Z","date_created":"2018-12-11T11:58:47Z","page":"11026 - 11035","day":"03","publication":"Journal of Neuroscience","publication_status":"published","year":"2003","month":"12","intvolume":" 23","quality_controlled":0,"publisher":"Society for Neuroscience","abstract":[{"text":"Metabotropic GABAB receptors mediate slow inhibitory effects presynaptically and postsynaptically. Using preembedding immunohistochemical methods combined with quantitative analysis of GABAB receptor subunit immunoreactivity, this study provides a detailed description of the cellular and subcellular localization of GABAB1a/b and GABA B2 in the rat hippocampus. At the light microscopic level, an overlapping distribution of GABAB1a/b and GABAB2 was revealed in the dendritic layers of the hippocampus. In addition, expression of the GABAB1a/b subunit was found in somata of CA1 pyramidal cells and of a subset of GABAergic interneurons. At the electron microscopic level, immunoreactivity for both subunits was observed on presynaptic and, more abundantly, on postsynaptic elements. Presynaptically, subunits were mainly detected in the extrasynaptic membrane and occasionally over the presynaptic membrane specialization of putative glutamatergic and, to a lesser extent, GABAergic axon terminals. Postsynaptically, the majority of GABAB receptor subunits were localized to the extrasynaptic plasma membrane of spines and dendritic shafts of principal cells and shafts of interneuron dendrites. Quantitative analysis revealed enrichment of GABAB1a/b around putative glutamatergic synapses on spines and an even distribution on dendritic shafts of pyramidal cells contacted by GABAergic boutons. The association of GABAB receptors with glutamatergic synapses at both presynaptic and postsynaptic sides indicates their intimate involvement in the modulation of glutamatergic neurotransmission. The dominant extrasynaptic localization of GABAB receptor subunits suggests that their activation is dependent on spillover of GABA requiring simultaneous activity of populations of GABAergic cells as it occurs during population oscillations or epileptic seizures.","lang":"eng"}],"title":"Subcellular Localization of Metabotropic GABAB Receptor Subunits GABAB1a/b and GABAB2 in the Rat Hippocampus","publist_id":"4263","author":[{"last_name":"Kulik","full_name":"Kulik, Ákos","first_name":"Ákos"},{"full_name":"Vida, Imre","last_name":"Vida","first_name":"Imre"},{"last_name":"Luján","full_name":"Luján, Rafael","first_name":"Rafael"},{"full_name":"Haas, Carola A","last_name":"Haas","first_name":"Carola"},{"first_name":"Guillermina","last_name":"López Bendito","full_name":"López-Bendito, Guillermina"},{"full_name":"Ryuichi Shigemoto","orcid":"0000-0001-8761-9444","last_name":"Shigemoto","first_name":"Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Michael","last_name":"Frotscher","full_name":"Frotscher, Michael"}],"extern":1,"date_updated":"2021-01-12T06:58:43Z","citation":{"ista":"Kulik Á, Vida I, Luján R, Haas C, López Bendito G, Shigemoto R, Frotscher M. 2003. Subcellular Localization of Metabotropic GABAB Receptor Subunits GABAB1a/b and GABAB2 in the Rat Hippocampus. Journal of Neuroscience. 23(35), 11026–11035.","chicago":"Kulik, Ákos, Imre Vida, Rafael Luján, Carola Haas, Guillermina López Bendito, Ryuichi Shigemoto, and Michael Frotscher. “Subcellular Localization of Metabotropic GABAB Receptor Subunits GABAB1a/b and GABAB2 in the Rat Hippocampus.” Journal of Neuroscience. Society for Neuroscience, 2003.","ieee":"Á. Kulik et al., “Subcellular Localization of Metabotropic GABAB Receptor Subunits GABAB1a/b and GABAB2 in the Rat Hippocampus,” Journal of Neuroscience, vol. 23, no. 35. Society for Neuroscience, pp. 11026–11035, 2003.","short":"Á. Kulik, I. Vida, R. Luján, C. Haas, G. López Bendito, R. Shigemoto, M. Frotscher, Journal of Neuroscience 23 (2003) 11026–11035.","ama":"Kulik Á, Vida I, Luján R, et al. Subcellular Localization of Metabotropic GABAB Receptor Subunits GABAB1a/b and GABAB2 in the Rat Hippocampus. Journal of Neuroscience. 2003;23(35):11026-11035.","apa":"Kulik, Á., Vida, I., Luján, R., Haas, C., López Bendito, G., Shigemoto, R., & Frotscher, M. (2003). Subcellular Localization of Metabotropic GABAB Receptor Subunits GABAB1a/b and GABAB2 in the Rat Hippocampus. Journal of Neuroscience. Society for Neuroscience.","mla":"Kulik, Ákos, et al. “Subcellular Localization of Metabotropic GABAB Receptor Subunits GABAB1a/b and GABAB2 in the Rat Hippocampus.” Journal of Neuroscience, vol. 23, no. 35, Society for Neuroscience, 2003, pp. 11026–35."},"status":"public","type":"journal_article","_id":"2635"},{"abstract":[{"text":"To better understand the role of neurotransmitter receptors in neuronal differentiation and maturation a detailed knowledge of their identity, location and function in the plasma membrane of specific neuronal populations during development is required. Combining pre-embedding immunocytochemistry with cell tracking in embryonic brain slice cultures we show that virtually all neurons (∼98%) migrating through the lower intermediate zone (LIZ) on their way from the medial ganglionic eminence to the cerebral cortex, express GABA BR1. Blockade of GABABRs with a specific antagonist, CGP52432, resulted in a concentration-dependent accumulation of these tangentially migrating neurons in the ventricular/subventricular zones (VZ/SVZ) of the cortex and fewer cells were observed in the cortical plate/marginal zone (CP/MZ) and LIZ. Moreover, they had significantly shorter leading processes compared with similar migrating cells in control slices. Electrophysiological recording in LIZ and CP cells revealed no direct effect of either CGP52432 or the GABABR agonist, baclofen, on resting membrane properties suggesting that the effect of CGP52432 on migration might be mediated through a metabotropic action or the regulation of release of factors controlling migration. These results suggest that GABABRs have an important modulatory role in the migration of cortical interneurons.","lang":"eng"}],"intvolume":" 13","month":"09","quality_controlled":0,"publisher":"Oxford University Press","publication":"Cerebral Cortex","day":"01","year":"2003","publication_status":"published","date_created":"2018-12-11T11:58:47Z","issue":"9","volume":13,"date_published":"2003-09-01T00:00:00Z","doi":"10.1093/cercor/13.9.932","page":"932 - 942","_id":"2634","status":"public","type":"journal_article","extern":1,"citation":{"mla":"López Bendito, Guillermina, et al. “Blockade of GABAB Receptors Alters the Tangential Migration of Cortical Neurons.” Cerebral Cortex, vol. 13, no. 9, Oxford University Press, 2003, pp. 932–42, doi:10.1093/cercor/13.9.932.","short":"G. López Bendito, R. Luján, R. Shigemoto, P. Ganter, O. Paulsen, Z. Molnár, Cerebral Cortex 13 (2003) 932–942.","ieee":"G. López Bendito, R. Luján, R. Shigemoto, P. Ganter, O. Paulsen, and Z. Molnár, “Blockade of GABAB receptors alters the tangential migration of cortical neurons,” Cerebral Cortex, vol. 13, no. 9. Oxford University Press, pp. 932–942, 2003.","apa":"López Bendito, G., Luján, R., Shigemoto, R., Ganter, P., Paulsen, O., & Molnár, Z. (2003). Blockade of GABAB receptors alters the tangential migration of cortical neurons. Cerebral Cortex. Oxford University Press. https://doi.org/10.1093/cercor/13.9.932","ama":"López Bendito G, Luján R, Shigemoto R, Ganter P, Paulsen O, Molnár Z. Blockade of GABAB receptors alters the tangential migration of cortical neurons. Cerebral Cortex. 2003;13(9):932-942. doi:10.1093/cercor/13.9.932","chicago":"López Bendito, Guillermina, Rafael Luján, Ryuichi Shigemoto, Paul Ganter, Ole Paulsen, and Zoltán Molnár. “Blockade of GABAB Receptors Alters the Tangential Migration of Cortical Neurons.” Cerebral Cortex. Oxford University Press, 2003. https://doi.org/10.1093/cercor/13.9.932.","ista":"López Bendito G, Luján R, Shigemoto R, Ganter P, Paulsen O, Molnár Z. 2003. Blockade of GABAB receptors alters the tangential migration of cortical neurons. Cerebral Cortex. 13(9), 932–942."},"date_updated":"2021-01-12T06:58:43Z","title":"Blockade of GABAB receptors alters the tangential migration of cortical neurons","author":[{"last_name":"López Bendito","full_name":"López-Bendito, Guillermina","first_name":"Guillermina"},{"first_name":"Rafael","last_name":"Luján","full_name":"Luján, Rafael"},{"id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","first_name":"Ryuichi","last_name":"Shigemoto","full_name":"Ryuichi Shigemoto","orcid":"0000-0001-8761-9444"},{"first_name":"Paul","full_name":"Ganter, Paul","last_name":"Ganter"},{"first_name":"Ole","full_name":"Paulsen, Ole","last_name":"Paulsen"},{"first_name":"Zoltán","full_name":"Molnár, Zoltán","last_name":"Molnár"}],"publist_id":"4264"},{"abstract":[{"text":"Taste-metabotropic glutamate receptor 4 (taste-mGluR4) and the heteromers of T1R1 and T1R3 are candidate receptors involved in the sense of umami (monosodium glutamate) taste. Although the expression of group III mGluRs (taste-mGluR4) has been demonstrated in taste tissues, no mention has been made of the expression of group I mGluRs (mGluR1 and mGluR5) in taste tissues. We examined the expression of mGluR1 and mGluR5 in rat gustatory tissues by using reverse transcription-polymerase chain reaction (RT-PCR), in situ hybridization, immunohistochemistry and immunoelectron microscopy. RT-PCR assay showed that mGluR1α and mGluR1β mRNAs were expressed in circumvallate papillae, but mGluR5 mRNA was not expressed. The positive signals of mGluR1 mRNA were detected only in circumvallate taste buds by in situ hybridization analysis. In cryosections of fungiform, foliate and circumvallate papillae, the antibody against mGluRla gave intense labeling on the taste hairs in all taste pores examined. In the developing taste buds, the positive signals of mGluR1α in taste hairs gradually increased with the increase in number of taste bud cells. These results show that, in addition to taste-mGluR4 and the heteromer of T1R1 and T1R3, mGluR1α may function as a receptor for glutamate (umami) taste sensation.","lang":"eng"}],"quality_controlled":0,"publisher":"Springer","intvolume":" 313","month":"07","year":"2003","publication_status":"published","publication":"Cell and Tissue Research","day":"01","page":"29 - 35","date_created":"2018-12-11T11:58:46Z","date_published":"2003-07-01T00:00:00Z","issue":"1","doi":"10.1007/s00441-003-0740-2","volume":313,"_id":"2630","type":"journal_article","status":"public","citation":{"ista":"Toyono T, Seta Y, Kataoka S, Kawano S, Shigemoto R, Toyoshima K. 2003. Expression of metabotropic glutamate receptor group I in rat gustatory papillae. Cell and Tissue Research. 313(1), 29–35.","chicago":"Toyono, Takashi, Yuji Seta, Shinji Kataoka, Shintaro Kawano, Ryuichi Shigemoto, and Kuniaki Toyoshima. “Expression of Metabotropic Glutamate Receptor Group I in Rat Gustatory Papillae.” Cell and Tissue Research. Springer, 2003. https://doi.org/10.1007/s00441-003-0740-2.","short":"T. Toyono, Y. Seta, S. Kataoka, S. Kawano, R. Shigemoto, K. Toyoshima, Cell and Tissue Research 313 (2003) 29–35.","ieee":"T. Toyono, Y. Seta, S. Kataoka, S. Kawano, R. Shigemoto, and K. Toyoshima, “Expression of metabotropic glutamate receptor group I in rat gustatory papillae,” Cell and Tissue Research, vol. 313, no. 1. Springer, pp. 29–35, 2003.","ama":"Toyono T, Seta Y, Kataoka S, Kawano S, Shigemoto R, Toyoshima K. Expression of metabotropic glutamate receptor group I in rat gustatory papillae. Cell and Tissue Research. 2003;313(1):29-35. doi:10.1007/s00441-003-0740-2","apa":"Toyono, T., Seta, Y., Kataoka, S., Kawano, S., Shigemoto, R., & Toyoshima, K. (2003). Expression of metabotropic glutamate receptor group I in rat gustatory papillae. Cell and Tissue Research. Springer. https://doi.org/10.1007/s00441-003-0740-2","mla":"Toyono, Takashi, et al. “Expression of Metabotropic Glutamate Receptor Group I in Rat Gustatory Papillae.” Cell and Tissue Research, vol. 313, no. 1, Springer, 2003, pp. 29–35, doi:10.1007/s00441-003-0740-2."},"date_updated":"2021-01-12T06:58:41Z","extern":1,"author":[{"full_name":"Toyono, Takashi","last_name":"Toyono","first_name":"Takashi"},{"last_name":"Seta","full_name":"Seta, Yuji","first_name":"Yuji"},{"first_name":"Shinji","full_name":"Kataoka, Shinji","last_name":"Kataoka"},{"first_name":"Shintaro","last_name":"Kawano","full_name":"Kawano, Shintaro"},{"last_name":"Shigemoto","orcid":"0000-0001-8761-9444","full_name":"Ryuichi Shigemoto","first_name":"Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Toyoshima, Kuniaki","last_name":"Toyoshima","first_name":"Kuniaki"}],"publist_id":"4267","title":"Expression of metabotropic glutamate receptor group I in rat gustatory papillae"},{"publication_status":"published","year":"2003","day":"19","publication":"Neuroscience Letters","page":"143 - 147","volume":353,"doi":"10.1016/j.neulet.2003.09.027","issue":"2","date_published":"2003-12-19T00:00:00Z","date_created":"2018-12-11T11:58:48Z","abstract":[{"lang":"eng","text":"While the cholinergic depletion in Alzheimer's disease (AD) has been known for some time, a definitive involvement of other neurotransmitter systems has been somewhat more elusive. Our study demonstrates a clear involvement of both glutamatergic and, to a lesser extent, GABAergic neurons in an early onset transgenic mouse model of AD-like amyloid pathology. Immunohistochemical staining and subsequent quantification has revealed a statistically significant increased density of glutamatergic and GABAergic presynaptic boutons in both the plaque free and plaque adjacent cortical neuropile areas of transgenic mice as compared to non-transgenic controls. Furthermore, amyloid plaque size was shown to have a statistically significant effect on the relative area occupied by dystrophic glutamatergic neurites in the peri-plaque neuropile. These findings support our hypothesis that the amyloid pathology progresses in a time and neurotransmitter specific manner, first in the cholinergic system which appears to be most vulnerable, followed by the glutamatergic presynaptic boutons and finally the somewhat more resilient GABAergic terminals."}],"quality_controlled":0,"publisher":"Elsevier","month":"12","intvolume":" 353","date_updated":"2021-01-12T06:58:44Z","citation":{"mla":"Bell, Karen, et al. “Structural Involvement of the Glutamatergic Presynaptic Boutons in a Transgenic Mouse Model Expressing Early Onset Amyloid Pathology.” Neuroscience Letters, vol. 353, no. 2, Elsevier, 2003, pp. 143–47, doi:10.1016/j.neulet.2003.09.027.","ieee":"K. Bell, G. J. De Kort, S. Steggerda, R. Shigemoto, A. Ribeiro Da Silva, and A. Cuello, “Structural involvement of the glutamatergic presynaptic boutons in a transgenic mouse model expressing early onset amyloid pathology,” Neuroscience Letters, vol. 353, no. 2. Elsevier, pp. 143–147, 2003.","short":"K. Bell, G.J. De Kort, S. Steggerda, R. Shigemoto, A. Ribeiro Da Silva, A. Cuello, Neuroscience Letters 353 (2003) 143–147.","apa":"Bell, K., De Kort, G. J., Steggerda, S., Shigemoto, R., Ribeiro Da Silva, A., & Cuello, A. (2003). Structural involvement of the glutamatergic presynaptic boutons in a transgenic mouse model expressing early onset amyloid pathology. Neuroscience Letters. Elsevier. https://doi.org/10.1016/j.neulet.2003.09.027","ama":"Bell K, De Kort GJ, Steggerda S, Shigemoto R, Ribeiro Da Silva A, Cuello A. Structural involvement of the glutamatergic presynaptic boutons in a transgenic mouse model expressing early onset amyloid pathology. Neuroscience Letters. 2003;353(2):143-147. doi:10.1016/j.neulet.2003.09.027","chicago":"Bell, Karen, G J De Kort, S Steggerda, Ryuichi Shigemoto, Alfredo Ribeiro Da Silva, and Augusto Cuello. “Structural Involvement of the Glutamatergic Presynaptic Boutons in a Transgenic Mouse Model Expressing Early Onset Amyloid Pathology.” Neuroscience Letters. Elsevier, 2003. https://doi.org/10.1016/j.neulet.2003.09.027.","ista":"Bell K, De Kort GJ, Steggerda S, Shigemoto R, Ribeiro Da Silva A, Cuello A. 2003. Structural involvement of the glutamatergic presynaptic boutons in a transgenic mouse model expressing early onset amyloid pathology. Neuroscience Letters. 353(2), 143–147."},"extern":1,"publist_id":"4262","author":[{"first_name":"Karen","full_name":"Bell, Karen F","last_name":"Bell"},{"full_name":"De Kort, G J","last_name":"De Kort","first_name":"G J"},{"full_name":"Steggerda, S","last_name":"Steggerda","first_name":"S"},{"first_name":"Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","last_name":"Shigemoto","full_name":"Ryuichi Shigemoto","orcid":"0000-0001-8761-9444"},{"first_name":"Alfredo","full_name":"Ribeiro-da-Silva, Alfredo","last_name":"Ribeiro Da Silva"},{"first_name":"Augusto","last_name":"Cuello","full_name":"Cuello, Augusto C"}],"title":"Structural involvement of the glutamatergic presynaptic boutons in a transgenic mouse model expressing early onset amyloid pathology","_id":"2637","type":"journal_article","status":"public"},{"type":"journal_article","status":"public","_id":"2784","author":[{"orcid":"0000-0003-2057-2754","full_name":"Björn Hof","last_name":"Hof","first_name":"Björn","id":"3A374330-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Anne","full_name":"Juel, Anne","last_name":"Juel"},{"first_name":"Tom","last_name":"Mullin","full_name":"Mullin, Tom P"}],"publist_id":"4105","title":"Magnetohydrodynamic damping of convective flows in molten gallium","date_updated":"2021-01-12T06:59:42Z","citation":{"ista":"Hof B, Juel A, Mullin T. 2003. Magnetohydrodynamic damping of convective flows in molten gallium. Journal of Fluid Mechanics. 482, 163–179.","chicago":"Hof, Björn, Anne Juel, and Tom Mullin. “Magnetohydrodynamic Damping of Convective Flows in Molten Gallium.” Journal of Fluid Mechanics. Cambridge University Press, 2003. https://doi.org/10.1017/S0022112003004014.","apa":"Hof, B., Juel, A., & Mullin, T. (2003). Magnetohydrodynamic damping of convective flows in molten gallium. Journal of Fluid Mechanics. Cambridge University Press. https://doi.org/10.1017/S0022112003004014","ama":"Hof B, Juel A, Mullin T. Magnetohydrodynamic damping of convective flows in molten gallium. Journal of Fluid Mechanics. 2003;482:163-179. doi:10.1017/S0022112003004014","ieee":"B. Hof, A. Juel, and T. Mullin, “Magnetohydrodynamic damping of convective flows in molten gallium,” Journal of Fluid Mechanics, vol. 482. Cambridge University Press, pp. 163–179, 2003.","short":"B. Hof, A. Juel, T. Mullin, Journal of Fluid Mechanics 482 (2003) 163–179.","mla":"Hof, Björn, et al. “Magnetohydrodynamic Damping of Convective Flows in Molten Gallium.” Journal of Fluid Mechanics, vol. 482, Cambridge University Press, 2003, pp. 163–79, doi:10.1017/S0022112003004014."},"extern":1,"quality_controlled":0,"publisher":"Cambridge University Press","month":"05","intvolume":" 482","abstract":[{"lang":"eng","text":"We report the results of an experimental study of magnetohydrodynamic damping of sidewall convection in a rectangular enclosure filled with gallium. In particular we investigate the suppression of convection when a steady magnetic field is applied separately in each of the three principal directions of the flow. The strongest damping of the steady flow is found for a vertical magnetic field, which is in agreement with theory. However, we observe that the application of a field transverse to the flow provides greater damping than a longitudinal one, which seems to contradict available theory. We provide a possible resolution of this apparent dichotomy in terms of the length scale of the experiment."}],"page":"163 - 179","date_published":"2003-05-13T00:00:00Z","doi":"10.1017/S0022112003004014","volume":482,"date_created":"2018-12-11T11:59:35Z","publication_status":"published","year":"2003","day":"13","publication":"Journal of Fluid Mechanics"},{"_id":"2785","status":"public","type":"journal_article","extern":1,"date_updated":"2021-01-12T06:59:42Z","citation":{"chicago":"Hof, Björn, Anne Juel, and Tom Mullin. “Scaling of the Turbulence Transition Threshold in a Pipe.” Physical Review Letters. American Physical Society, 2003. https://doi.org/10.1103/PhysRevLett.91.244502.","ista":"Hof B, Juel A, Mullin T. 2003. Scaling of the turbulence transition threshold in a pipe. Physical Review Letters. 91(24), 244502/1-244502/4.","mla":"Hof, Björn, et al. “Scaling of the Turbulence Transition Threshold in a Pipe.” Physical Review Letters, vol. 91, no. 24, American Physical Society, 2003, p. 244502/1-244502/4, doi:10.1103/PhysRevLett.91.244502.","apa":"Hof, B., Juel, A., & Mullin, T. (2003). Scaling of the turbulence transition threshold in a pipe. Physical Review Letters. American Physical Society. https://doi.org/10.1103/PhysRevLett.91.244502","ama":"Hof B, Juel A, Mullin T. Scaling of the turbulence transition threshold in a pipe. Physical Review Letters. 2003;91(24):244502/1-244502/4. doi:10.1103/PhysRevLett.91.244502","ieee":"B. Hof, A. Juel, and T. Mullin, “Scaling of the turbulence transition threshold in a pipe,” Physical Review Letters, vol. 91, no. 24. American Physical Society, p. 244502/1-244502/4, 2003.","short":"B. Hof, A. Juel, T. Mullin, Physical Review Letters 91 (2003) 244502/1-244502/4."},"title":"Scaling of the turbulence transition threshold in a pipe","author":[{"last_name":"Hof","full_name":"Björn Hof","orcid":"0000-0003-2057-2754","first_name":"Björn","id":"3A374330-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Anne","last_name":"Juel","full_name":"Juel, Anne"},{"last_name":"Mullin","full_name":"Mullin, Tom P","first_name":"Tom"}],"publist_id":"4104","abstract":[{"text":"Experimental evidence for the scaling of the finite amplitude of perturbation theory required to promote transition in Poiseuille flow was found. The exponent is -1 and was uncovered using considerable care in the design and execution of the experiment. Interestingly, this exponent was also found in experiments on transition in boundary layers.","lang":"eng"}],"intvolume":" 91","month":"12","publisher":"American Physical Society","quality_controlled":0,"publication":"Physical Review Letters","day":"12","year":"2003","publication_status":"published","date_created":"2018-12-11T11:59:35Z","date_published":"2003-12-12T00:00:00Z","volume":91,"doi":"10.1103/PhysRevLett.91.244502","issue":"24","page":"244502/1 - 244502/4"},{"title":"Auxin transport - Shaping the plant","publist_id":"3711","author":[{"last_name":"Friml","orcid":"0000-0002-8302-7596","full_name":"Friml, Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87","first_name":"Jirí"}],"extern":"1","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","date_updated":"2021-01-12T07:40:17Z","citation":{"ista":"Friml J. 2003. Auxin transport - Shaping the plant. Current Opinion in Plant Biology. 6(1), 7–12.","chicago":"Friml, Jiří. “Auxin Transport - Shaping the Plant.” Current Opinion in Plant Biology. Elsevier, 2003. https://doi.org/10.1016/S1369526602000031.","ieee":"J. Friml, “Auxin transport - Shaping the plant,” Current Opinion in Plant Biology, vol. 6, no. 1. Elsevier, pp. 7–12, 2003.","short":"J. Friml, Current Opinion in Plant Biology 6 (2003) 7–12.","apa":"Friml, J. (2003). Auxin transport - Shaping the plant. Current Opinion in Plant Biology. Elsevier. https://doi.org/10.1016/S1369526602000031","ama":"Friml J. Auxin transport - Shaping the plant. Current Opinion in Plant Biology. 2003;6(1):7-12. doi:10.1016/S1369526602000031","mla":"Friml, Jiří. “Auxin Transport - Shaping the Plant.” Current Opinion in Plant Biology, vol. 6, no. 1, Elsevier, 2003, pp. 7–12, doi:10.1016/S1369526602000031."},"status":"public","type":"journal_article","_id":"2990","doi":"10.1016/S1369526602000031","date_published":"2003-02-01T00:00:00Z","issue":"1","volume":6,"date_created":"2018-12-11T12:00:43Z","page":"7 - 12","day":"01","language":[{"iso":"eng"}],"publication":"Current Opinion in Plant Biology","publication_status":"published","year":"2003","month":"02","intvolume":" 6","publisher":"Elsevier","quality_controlled":"1","oa_version":"None","abstract":[{"lang":"eng","text":"Plant growth is marked by its adaptability to continuous changes in environment. A regulated, differential distribution of auxin underlies many adaptation processes including organogenesis, meristem patterning and tropisms. In executing its multiple roles, auxin displays some characteristics of both a hormone and a morphogen. Studies on auxin transport, as well as tracing the intracellular movement of its molecular components, have suggested a possible scenario to explain how growth plasticity is conferred at the cellular and molecular level. The plant perceives stimuli and changes the subcellular position of auxin-transport components accordingly. These changes modulate auxin fluxes, and the newly established auxin distribution triggers the corresponding developmental response."}]},{"abstract":[{"text":"Plants have many polarized cell types, but relatively little is known about the mechanisms that establish polarity. The orc mutant was identified originally by defects in root patterning, and positional cloning revealed that the affected gene encodes STEROL METHYLTRANSFERASE1, which is required for the appropriate synthesis and composition of major membrane sterols. smt1orc mutants displayed several conspicuous cell polarity defects. Columella root cap cells revealed perturbed polar positioning of different organelles, and in the smt1orc root epidermis, polar initiation of root hairs was more randomized. Polar auxin transport and expression of the auxin reporter DR5-β-glucuronidase were aberrant in smt1orc. Patterning defects in smt1orc resembled those observed in mutants of the PIN gene family of putative auxin efflux transporters. Consistently, the membrane localization of the PIN1 and PIN3 proteins was disturbed in smt1orc, whereas polar positioning of the influx carrier AUX1 appeared normal. Our results suggest that balanced sterol composition is a major requirement for cell polarity and auxin efflux in Arabidopsis.","lang":"eng"}],"intvolume":" 15","month":"03","publisher":"American Society of Plant Biologists","quality_controlled":0,"publication":"Plant Cell","day":"01","publication_status":"published","year":"2003","date_created":"2018-12-11T12:00:44Z","issue":"3","doi":"10.1105/tpc.008433","volume":15,"date_published":"2003-03-01T00:00:00Z","page":"612 - 625","_id":"2992","status":"public","type":"journal_article","extern":1,"citation":{"mla":"Willemsen, Viola, et al. “Cell Polarity and PIN Protein Positioning in Arabidopsis Require STEROL METHYLTRANSFERASE1 Function.” Plant Cell, vol. 15, no. 3, American Society of Plant Biologists, 2003, pp. 612–25, doi:10.1105/tpc.008433.","ama":"Willemsen V, Friml J, Grebe M, Van Den Toorn A, Palme K, Scheres B. Cell polarity and PIN protein positioning in Arabidopsis require STEROL METHYLTRANSFERASE1 function. Plant Cell. 2003;15(3):612-625. doi:10.1105/tpc.008433","apa":"Willemsen, V., Friml, J., Grebe, M., Van Den Toorn, A., Palme, K., & Scheres, B. (2003). Cell polarity and PIN protein positioning in Arabidopsis require STEROL METHYLTRANSFERASE1 function. Plant Cell. American Society of Plant Biologists. https://doi.org/10.1105/tpc.008433","short":"V. Willemsen, J. Friml, M. Grebe, A. Van Den Toorn, K. Palme, B. Scheres, Plant Cell 15 (2003) 612–625.","ieee":"V. Willemsen, J. Friml, M. Grebe, A. Van Den Toorn, K. Palme, and B. Scheres, “Cell polarity and PIN protein positioning in Arabidopsis require STEROL METHYLTRANSFERASE1 function,” Plant Cell, vol. 15, no. 3. American Society of Plant Biologists, pp. 612–625, 2003.","chicago":"Willemsen, Viola, Jiří Friml, Markus Grebe, Albert Van Den Toorn, Klaus Palme, and Ben Scheres. “Cell Polarity and PIN Protein Positioning in Arabidopsis Require STEROL METHYLTRANSFERASE1 Function.” Plant Cell. American Society of Plant Biologists, 2003. https://doi.org/10.1105/tpc.008433.","ista":"Willemsen V, Friml J, Grebe M, Van Den Toorn A, Palme K, Scheres B. 2003. Cell polarity and PIN protein positioning in Arabidopsis require STEROL METHYLTRANSFERASE1 function. Plant Cell. 15(3), 612–625."},"date_updated":"2021-01-12T07:40:18Z","title":"Cell polarity and PIN protein positioning in Arabidopsis require STEROL METHYLTRANSFERASE1 function","publist_id":"3710","author":[{"first_name":"Viola","full_name":"Willemsen, Viola","last_name":"Willemsen"},{"first_name":"Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","full_name":"Jirí Friml","orcid":"0000-0002-8302-7596"},{"first_name":"Markus","full_name":"Grebe, Markus","last_name":"Grebe"},{"last_name":"Van Den Toorn","full_name":"Van Den Toorn, Albert","first_name":"Albert"},{"first_name":"Klaus","last_name":"Palme","full_name":"Palme, Klaus"},{"full_name":"Scheres, Ben","last_name":"Scheres","first_name":"Ben"}]},{"status":"public","type":"journal_article","_id":"2996","title":"Local, efflux-dependent auxin gradients as a common module for plant organ formation","author":[{"id":"38F4F166-F248-11E8-B48F-1D18A9856A87","first_name":"Eva","last_name":"Benková","orcid":"0000-0002-8510-9739","full_name":"Eva Benková"},{"first_name":"Marta","last_name":"Michniewicz","full_name":"Michniewicz, Marta"},{"full_name":"Sauer, Michael","last_name":"Sauer","first_name":"Michael"},{"full_name":"Teichmann, Thomas","last_name":"Teichmann","first_name":"Thomas"},{"last_name":"Seifertová","full_name":"Seifertová, Daniela","first_name":"Daniela"},{"first_name":"Gerd","full_name":"Jürgens, Gerd","last_name":"Jürgens"},{"first_name":"Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","orcid":"0000-0002-8302-7596","full_name":"Jirí Friml"}],"publist_id":"3706","extern":1,"citation":{"chicago":"Benková, Eva, Marta Michniewicz, Michael Sauer, Thomas Teichmann, Daniela Seifertová, Gerd Jürgens, and Jiří Friml. “Local, Efflux-Dependent Auxin Gradients as a Common Module for Plant Organ Formation.” Cell. Cell Press, 2003. https://doi.org/10.1016/S0092-8674(03)00924-3.","ista":"Benková E, Michniewicz M, Sauer M, Teichmann T, Seifertová D, Jürgens G, Friml J. 2003. Local, efflux-dependent auxin gradients as a common module for plant organ formation. Cell. 115(5), 591–602.","mla":"Benková, Eva, et al. “Local, Efflux-Dependent Auxin Gradients as a Common Module for Plant Organ Formation.” Cell, vol. 115, no. 5, Cell Press, 2003, pp. 591–602, doi:10.1016/S0092-8674(03)00924-3.","apa":"Benková, E., Michniewicz, M., Sauer, M., Teichmann, T., Seifertová, D., Jürgens, G., & Friml, J. (2003). Local, efflux-dependent auxin gradients as a common module for plant organ formation. Cell. Cell Press. https://doi.org/10.1016/S0092-8674(03)00924-3","ama":"Benková E, Michniewicz M, Sauer M, et al. Local, efflux-dependent auxin gradients as a common module for plant organ formation. Cell. 2003;115(5):591-602. doi:10.1016/S0092-8674(03)00924-3","ieee":"E. Benková et al., “Local, efflux-dependent auxin gradients as a common module for plant organ formation,” Cell, vol. 115, no. 5. Cell Press, pp. 591–602, 2003.","short":"E. Benková, M. Michniewicz, M. Sauer, T. Teichmann, D. Seifertová, G. Jürgens, J. Friml, Cell 115 (2003) 591–602."},"date_updated":"2021-01-12T07:40:19Z","month":"11","intvolume":" 115","quality_controlled":0,"publisher":"Cell Press","abstract":[{"text":"Plants, compared to animals, exhibit an amazing adaptability and plasticity in their development. This is largely dependent on the ability of plants to form new organs, such as lateral roots, leaves, and flowers during postembryonic development. Organ primordia develop from founder cell populations into organs by coordinated cell division and differentiation. Here, we show that organ formation in Arabidopsis involves dynamic gradients of the signaling molecule auxin with maxima at the primordia tips. These gradients are mediated by cellular efflux requiring asymmetrically localized PIN proteins, which represent a functionally redundant network for auxin distribution in both aerial and underground organs. PIN1 polar localization undergoes a dynamic rearrangement, which correlates with establishment of auxin gradients and primordium development. Our results suggest that PIN-dependent, local auxin gradients represent a common module for formation of all plant organs, regardless of their mature morphology or developmental origin.\n","lang":"eng"}],"date_published":"2003-11-26T00:00:00Z","doi":"10.1016/S0092-8674(03)00924-3","issue":"5","volume":115,"date_created":"2018-12-11T12:00:46Z","page":"591 - 602","day":"26","publication":"Cell","publication_status":"published","year":"2003"},{"abstract":[{"text":"Axis formation occurs in plants, as in animals, during early embryogenesis. However, the underlying mechanism is not known. Here we show that the first manifestation of the apical-basal axis in plants, the asymmetric division of the zygote, produces a basal cell that transports and an apical cell that responds to the signalling molecule auxin. This apical-basal auxin activity gradient triggers the specification of apical embryo structures and is actively maintained by a novel component of auxin efflux, PIN7, which is located apically in the basal cell. Later, the developmentally regulated reversal of PIN7 and onset of PIN1 polar localization reorganize the auxin gradient for specification of the basal root pole. An analysis of pin quadruple mutants identifies PIN-dependent transport as an essential part of the mechanism for embryo axis formation. Our results indicate how the establishment of cell polarity, polar auxin efflux and local auxin response result in apical-basal axis formation of the embryo, and thus determine the axiality of the adult plant.\n","lang":"eng"}],"month":"11","intvolume":" 426","quality_controlled":0,"publisher":"Nature Publishing Group","day":"13","publication":"Nature","publication_status":"published","year":"2003","volume":426,"issue":"6963","date_published":"2003-11-13T00:00:00Z","doi":"10.1038/nature02085","date_created":"2018-12-11T12:00:45Z","page":"147 - 153","_id":"2995","status":"public","type":"journal_article","extern":1,"citation":{"ieee":"J. Friml et al., “Efflux dependent auxin gradients establish the apical basal axis of Arabidopsis,” Nature, vol. 426, no. 6963. Nature Publishing Group, pp. 147–153, 2003.","short":"J. Friml, A. Vieten, M. Sauer, D. Weijers, H. Schwarz, T. Hamann, R. Offringa, G. Jürgens, Nature 426 (2003) 147–153.","ama":"Friml J, Vieten A, Sauer M, et al. Efflux dependent auxin gradients establish the apical basal axis of Arabidopsis. Nature. 2003;426(6963):147-153. doi:10.1038/nature02085","apa":"Friml, J., Vieten, A., Sauer, M., Weijers, D., Schwarz, H., Hamann, T., … Jürgens, G. (2003). Efflux dependent auxin gradients establish the apical basal axis of Arabidopsis. Nature. Nature Publishing Group. https://doi.org/10.1038/nature02085","mla":"Friml, Jiří, et al. “Efflux Dependent Auxin Gradients Establish the Apical Basal Axis of Arabidopsis.” Nature, vol. 426, no. 6963, Nature Publishing Group, 2003, pp. 147–53, doi:10.1038/nature02085.","ista":"Friml J, Vieten A, Sauer M, Weijers D, Schwarz H, Hamann T, Offringa R, Jürgens G. 2003. Efflux dependent auxin gradients establish the apical basal axis of Arabidopsis. Nature. 426(6963), 147–153.","chicago":"Friml, Jiří, Anne Vieten, Michael Sauer, Dolf Weijers, Heinz Schwarz, Thorsten Hamann, Remko Offringa, and Gerd Jürgens. “Efflux Dependent Auxin Gradients Establish the Apical Basal Axis of Arabidopsis.” Nature. Nature Publishing Group, 2003. https://doi.org/10.1038/nature02085."},"date_updated":"2021-01-12T07:40:19Z","title":"Efflux dependent auxin gradients establish the apical basal axis of Arabidopsis","publist_id":"3708","author":[{"first_name":"Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Jirí Friml","orcid":"0000-0002-8302-7596","last_name":"Friml"},{"full_name":"Vieten, Anne","last_name":"Vieten","first_name":"Anne"},{"last_name":"Sauer","full_name":"Sauer, Michael","first_name":"Michael"},{"first_name":"Dolf","last_name":"Weijers","full_name":"Weijers, Dolf"},{"last_name":"Schwarz","full_name":"Schwarz, Heinz","first_name":"Heinz"},{"first_name":"Thorsten","full_name":"Hamann, Thorsten","last_name":"Hamann"},{"first_name":"Remko","full_name":"Offringa, Remko","last_name":"Offringa"},{"first_name":"Gerd","full_name":"Jürgens, Gerd","last_name":"Jürgens"}]},{"date_updated":"2021-01-12T07:40:18Z","citation":{"chicago":"Reinhardt, Didier, Eva Pesce, Pia Stieger, Therese Mandel, Kurt Baltensperger, Malcolm Bennett, Jan Traas, Jiří Friml, and Cris Kuhlemeier. “Regulation of Phyllotaxis by Polar Auxin Transport.” Nature. Nature Publishing Group, 2003. https://doi.org/10.1038/nature02081.","ista":"Reinhardt D, Pesce E, Stieger P, Mandel T, Baltensperger K, Bennett M, Traas J, Friml J, Kuhlemeier C. 2003. Regulation of phyllotaxis by polar auxin transport. Nature. 426(6964), 255–260.","mla":"Reinhardt, Didier, et al. “Regulation of Phyllotaxis by Polar Auxin Transport.” Nature, vol. 426, no. 6964, Nature Publishing Group, 2003, pp. 255–60, doi:10.1038/nature02081.","apa":"Reinhardt, D., Pesce, E., Stieger, P., Mandel, T., Baltensperger, K., Bennett, M., … Kuhlemeier, C. (2003). Regulation of phyllotaxis by polar auxin transport. Nature. Nature Publishing Group. https://doi.org/10.1038/nature02081","ama":"Reinhardt D, Pesce E, Stieger P, et al. Regulation of phyllotaxis by polar auxin transport. Nature. 2003;426(6964):255-260. doi:10.1038/nature02081","ieee":"D. Reinhardt et al., “Regulation of phyllotaxis by polar auxin transport,” Nature, vol. 426, no. 6964. Nature Publishing Group, pp. 255–260, 2003.","short":"D. Reinhardt, E. Pesce, P. Stieger, T. Mandel, K. Baltensperger, M. Bennett, J. Traas, J. Friml, C. Kuhlemeier, Nature 426 (2003) 255–260."},"extern":1,"publist_id":"3707","author":[{"full_name":"Reinhardt, Didier","last_name":"Reinhardt","first_name":"Didier"},{"first_name":"Eva","full_name":"Pesce, Eva-Rachele","last_name":"Pesce"},{"full_name":"Stieger, Pia","last_name":"Stieger","first_name":"Pia"},{"full_name":"Mandel, Therese","last_name":"Mandel","first_name":"Therese"},{"full_name":"Baltensperger, Kurt","last_name":"Baltensperger","first_name":"Kurt"},{"first_name":"Malcolm","last_name":"Bennett","full_name":"Bennett, Malcolm"},{"first_name":"Jan","full_name":"Traas, Jan","last_name":"Traas"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","first_name":"Jirí","full_name":"Jirí Friml","orcid":"0000-0002-8302-7596","last_name":"Friml"},{"first_name":"Cris","full_name":"Kuhlemeier, Cris","last_name":"Kuhlemeier"}],"title":"Regulation of phyllotaxis by polar auxin transport","_id":"2994","type":"journal_article","status":"public","publication_status":"published","year":"2003","day":"20","publication":"Nature","page":"255 - 260","volume":426,"issue":"6964","doi":"10.1038/nature02081","date_published":"2003-11-20T00:00:00Z","date_created":"2018-12-11T12:00:45Z","abstract":[{"lang":"eng","text":"The regular arrangement of leaves around a plant's stem, called phyllotaxis, has for centuries attracted the attention of philosophers, mathematicians and natural scientists; however, to date, studies of phyllotaxis have been largely theoretical. Leaves and flowers are formed from the shoot apical meristem, triggered by the plant hormone auxin. Auxin is transported through plant tissues by specific cellular influx and efflux carrier proteins. Here we show that proteins involved in auxin transport regulate phyllotaxis. Our data indicate that auxin is transported upwards into the meristem through the epidermis and the outermost meristem cell layer. Existing leaf primordia act as sinks, redistributing auxin and creating its heterogeneous distribution in the meristem. Auxin accumulation occurs only at certain minimal distances from existing primordia, defining the position of future primordia. This model for phyllotaxis accounts for its reiterative nature, as well as its regularity and stability."}],"publisher":"Nature Publishing Group","quality_controlled":0,"month":"11","intvolume":" 426"},{"date_created":"2018-12-11T12:00:44Z","issue":"1","date_published":"2003-04-01T00:00:00Z","doi":"10.1046/j.1365-313X.2003.01705.x","volume":34,"page":"115 - 124","publication":"Plant Journal","day":"01","year":"2003","publication_status":"published","intvolume":" 34","month":"04","quality_controlled":0,"publisher":"Wiley-Blackwell","abstract":[{"text":"Plant biology is currently experiencing a growing demand for easy and reliable mRNA and protein localisation techniques. Here, we present novel whole mount in situ hybridisation and immunolocalisation protocols, suitable to localise mRNAs and proteins in Arabidopsis seedlings. We demonstrate that these methods can be used in different organs of Arabidopsis seedlings as well as in other plant species. In order to achieve better reproducibility and higher throughput, we modified these protocols for automation to be performed by a liquid handling robot. In addition, we show that other procedures such as reporter enzyme assays and tissue clearing can be similarly automated. We present examples of application of our protocols including mRNA localisation and proteins and epitope tag (co)localisations which demonstrate that these methods provide reliable and versatile tools for expression, localisation and anatomical studies in plants.","lang":"eng"}],"title":"Automated whole mount localisation techniques for plant seedlings","author":[{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","first_name":"Jirí","last_name":"Friml","full_name":"Jirí Friml","orcid":"0000-0002-8302-7596"},{"first_name":"Eva","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8510-9739","full_name":"Eva Benková","last_name":"Benková"},{"full_name":"Mayer, Ulrike","last_name":"Mayer","first_name":"Ulrike"},{"first_name":"Klaus","last_name":"Palme","full_name":"Palme, Klaus"},{"full_name":"Muster, Gerhard","last_name":"Muster","first_name":"Gerhard"}],"publist_id":"3709","extern":1,"date_updated":"2021-01-12T07:40:18Z","citation":{"ieee":"J. Friml, E. Benková, U. Mayer, K. Palme, and G. Muster, “Automated whole mount localisation techniques for plant seedlings,” Plant Journal, vol. 34, no. 1. Wiley-Blackwell, pp. 115–124, 2003.","short":"J. Friml, E. Benková, U. Mayer, K. Palme, G. Muster, Plant Journal 34 (2003) 115–124.","ama":"Friml J, Benková E, Mayer U, Palme K, Muster G. Automated whole mount localisation techniques for plant seedlings. Plant Journal. 2003;34(1):115-124. doi:10.1046/j.1365-313X.2003.01705.x","apa":"Friml, J., Benková, E., Mayer, U., Palme, K., & Muster, G. (2003). Automated whole mount localisation techniques for plant seedlings. Plant Journal. Wiley-Blackwell. https://doi.org/10.1046/j.1365-313X.2003.01705.x","mla":"Friml, Jiří, et al. “Automated Whole Mount Localisation Techniques for Plant Seedlings.” Plant Journal, vol. 34, no. 1, Wiley-Blackwell, 2003, pp. 115–24, doi:10.1046/j.1365-313X.2003.01705.x.","ista":"Friml J, Benková E, Mayer U, Palme K, Muster G. 2003. Automated whole mount localisation techniques for plant seedlings. Plant Journal. 34(1), 115–124.","chicago":"Friml, Jiří, Eva Benková, Ulrike Mayer, Klaus Palme, and Gerhard Muster. “Automated Whole Mount Localisation Techniques for Plant Seedlings.” Plant Journal. Wiley-Blackwell, 2003. https://doi.org/10.1046/j.1365-313X.2003.01705.x."},"status":"public","type":"journal_article","_id":"2993"},{"intvolume":" 163","month":"01","quality_controlled":0,"publisher":"Genetics Society of America","abstract":[{"text":"Biosynthesis of most peptide hormones and neuropeptides requires proteolytic excision of the active peptide from inactive proprotein precursors, an activity carried out by subtilisin-like proprotein convertases (SPCs) in constitutive or regulated secretory pathways. The Drosophila amontillado (amon) gene encodes a homolog of the mammalian PC2 protein, an SPC that functions in the regulated secretory pathway in neuroendocrine tissues. We have identified amon mutants by isolating ethylmethanesulfonate (EMS)-induced lethal and visible mutations that define two complementation groups in the amon interval at 97D1 of the third chromosome. DNA sequencing identified the amon complementation group and the DNA sequence change for each of the nine amon alleles isolated. amon mutants display partial embryonic lethality, are defective in larval growth, and arrest during the first to second instar larval molt. Mutant larvae can be rescued by heat-shock-induced expression of the amon protein. Rescued larvae arrest at the subsequent larval molt, suggesting that amon is also required for the second to third instar larval molt. Our data indicate that the amon proprotein convertase is required during embryogenesis and larval development in Drosophila and support the hypothesis that AMON acts to proteolytically process peptide hormones that regulate hatching, larval growth, and larval ecdysis.","lang":"eng"}],"date_created":"2018-12-11T12:01:41Z","volume":163,"issue":"1","date_published":"2003-01-01T00:00:00Z","page":"227 - 237","publication":"Genetics","day":"01","year":"2003","publication_status":"published","status":"public","type":"journal_article","_id":"3151","title":"Amontillado, the Drosophila homolog of the prohormone processing protease PC2, is required during embryogenesis and early larval development","publist_id":"3545","author":[{"last_name":"Rayburn","full_name":"Rayburn, Lowell Y","first_name":"Lowell"},{"first_name":"Holly","last_name":"Gooding","full_name":"Gooding, Holly C"},{"last_name":"Choksi","full_name":"Choksi, Semil P","first_name":"Semil"},{"full_name":"Maloney, Dhea","last_name":"Maloney","first_name":"Dhea"},{"full_name":"Kidd, Ambrose R","last_name":"Kidd","first_name":"Ambrose"},{"id":"3D224B9E-F248-11E8-B48F-1D18A9856A87","first_name":"Daria E","last_name":"Siekhaus","orcid":"0000-0001-8323-8353","full_name":"Daria Siekhaus"},{"last_name":"Bender","full_name":"Bender, Michael","first_name":"Michael"}],"extern":1,"date_updated":"2021-01-12T07:41:25Z","citation":{"ista":"Rayburn L, Gooding H, Choksi S, Maloney D, Kidd A, Siekhaus DE, Bender M. 2003. Amontillado, the Drosophila homolog of the prohormone processing protease PC2, is required during embryogenesis and early larval development. Genetics. 163(1), 227–237.","chicago":"Rayburn, Lowell, Holly Gooding, Semil Choksi, Dhea Maloney, Ambrose Kidd, Daria E Siekhaus, and Michael Bender. “Amontillado, the Drosophila Homolog of the Prohormone Processing Protease PC2, Is Required during Embryogenesis and Early Larval Development.” Genetics. Genetics Society of America, 2003.","apa":"Rayburn, L., Gooding, H., Choksi, S., Maloney, D., Kidd, A., Siekhaus, D. E., & Bender, M. (2003). Amontillado, the Drosophila homolog of the prohormone processing protease PC2, is required during embryogenesis and early larval development. Genetics. Genetics Society of America.","ama":"Rayburn L, Gooding H, Choksi S, et al. Amontillado, the Drosophila homolog of the prohormone processing protease PC2, is required during embryogenesis and early larval development. Genetics. 2003;163(1):227-237.","ieee":"L. Rayburn et al., “Amontillado, the Drosophila homolog of the prohormone processing protease PC2, is required during embryogenesis and early larval development,” Genetics, vol. 163, no. 1. Genetics Society of America, pp. 227–237, 2003.","short":"L. Rayburn, H. Gooding, S. Choksi, D. Maloney, A. Kidd, D.E. Siekhaus, M. Bender, Genetics 163 (2003) 227–237.","mla":"Rayburn, Lowell, et al. “Amontillado, the Drosophila Homolog of the Prohormone Processing Protease PC2, Is Required during Embryogenesis and Early Larval Development.” Genetics, vol. 163, no. 1, Genetics Society of America, 2003, pp. 227–37."}},{"date_published":"2003-03-01T00:00:00Z","volume":5,"doi":"10.1038/ncb941","issue":"3","date_created":"2018-12-11T12:01:41Z","page":"231 - 235","day":"01","publication":"Nature Cell Biology","publication_status":"published","year":"2003","month":"03","intvolume":" 5","publisher":"Nature Publishing Group","quality_controlled":0,"abstract":[{"lang":"eng","text":"Tripartite G-protein-coupled receptors (GPCRs) represent one of the largest groups of signal transducers, transmitting signals from hormones, neuropeptides, odorants, food and light. Ligand-bound receptors catalyse GDP/GTP exchange on the G-protein α-subunit (Gα), leading to α-GTP separation from the βγ subunits and pathway activation. Activating mutations in the receptors or G proteins underlie many human diseases, including some cancers, dwarfism and premature puberty. Regulators of G-protein signalling (RGS proteins) are known to modulate the level and duration of ligand-induced signalling by accelerating the intrinsic GTPase activity of the Gα subunit, and thus reformation of the inactive GDP-bound Gα. Here we find that even in the absence of receptor, mutation of the RGS family member Sst2 (refs 6-9) permits spontaneous activation of the G-protein-coupled mating pathway in Saccharomyces cerevisiae at levels normally seen only in the presence of ligand. Our work demonstrates the occurence of spontaneous tripartite G-protein signalling in vivo and identifies a requirement for RGS proteins in preventing such receptor-independent activation."}],"title":"Spontaneous receptor-independent heterotrimeric G-protein signalling in an RGS mutant","publist_id":"3544","author":[{"full_name":"Daria Siekhaus","orcid":"0000-0001-8323-8353","last_name":"Siekhaus","id":"3D224B9E-F248-11E8-B48F-1D18A9856A87","first_name":"Daria E"},{"full_name":"Drubin, David G","last_name":"Drubin","first_name":"David"}],"extern":1,"citation":{"chicago":"Siekhaus, Daria E, and David Drubin. “Spontaneous Receptor-Independent Heterotrimeric G-Protein Signalling in an RGS Mutant.” Nature Cell Biology. Nature Publishing Group, 2003. https://doi.org/10.1038/ncb941.","ista":"Siekhaus DE, Drubin D. 2003. Spontaneous receptor-independent heterotrimeric G-protein signalling in an RGS mutant. Nature Cell Biology. 5(3), 231–235.","mla":"Siekhaus, Daria E., and David Drubin. “Spontaneous Receptor-Independent Heterotrimeric G-Protein Signalling in an RGS Mutant.” Nature Cell Biology, vol. 5, no. 3, Nature Publishing Group, 2003, pp. 231–35, doi:10.1038/ncb941.","apa":"Siekhaus, D. E., & Drubin, D. (2003). Spontaneous receptor-independent heterotrimeric G-protein signalling in an RGS mutant. Nature Cell Biology. Nature Publishing Group. https://doi.org/10.1038/ncb941","ama":"Siekhaus DE, Drubin D. Spontaneous receptor-independent heterotrimeric G-protein signalling in an RGS mutant. Nature Cell Biology. 2003;5(3):231-235. doi:10.1038/ncb941","ieee":"D. E. Siekhaus and D. Drubin, “Spontaneous receptor-independent heterotrimeric G-protein signalling in an RGS mutant,” Nature Cell Biology, vol. 5, no. 3. Nature Publishing Group, pp. 231–235, 2003.","short":"D.E. Siekhaus, D. Drubin, Nature Cell Biology 5 (2003) 231–235."},"date_updated":"2021-01-12T07:41:24Z","status":"public","type":"journal_article","_id":"3150"},{"publist_id":"3472","author":[{"last_name":"Pietrzak","full_name":"Krzysztof Pietrzak","orcid":"0000-0002-9139-1654","first_name":"Krzysztof Z","id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87"}],"title":"On the parameterized complexity of the fixed alphabet shortest common supersequence and longest common subsequence problems","citation":{"chicago":"Pietrzak, Krzysztof Z. “On the Parameterized Complexity of the Fixed Alphabet Shortest Common Supersequence and Longest Common Subsequence Problems.” Journal of Computer and System Sciences. Elsevier, 2003. https://doi.org/10.1016/S0022-0000(03)00078-3.","ista":"Pietrzak KZ. 2003. On the parameterized complexity of the fixed alphabet shortest common supersequence and longest common subsequence problems. Journal of Computer and System Sciences. 67(4), 757–771.","mla":"Pietrzak, Krzysztof Z. “On the Parameterized Complexity of the Fixed Alphabet Shortest Common Supersequence and Longest Common Subsequence Problems.” Journal of Computer and System Sciences, vol. 67, no. 4, Elsevier, 2003, pp. 757–71, doi:10.1016/S0022-0000(03)00078-3.","apa":"Pietrzak, K. Z. (2003). On the parameterized complexity of the fixed alphabet shortest common supersequence and longest common subsequence problems. Journal of Computer and System Sciences. Elsevier. https://doi.org/10.1016/S0022-0000(03)00078-3","ama":"Pietrzak KZ. On the parameterized complexity of the fixed alphabet shortest common supersequence and longest common subsequence problems. Journal of Computer and System Sciences. 2003;67(4):757-771. doi:10.1016/S0022-0000(03)00078-3","ieee":"K. Z. Pietrzak, “On the parameterized complexity of the fixed alphabet shortest common supersequence and longest common subsequence problems,” Journal of Computer and System Sciences, vol. 67, no. 4. Elsevier, pp. 757–771, 2003.","short":"K.Z. Pietrzak, Journal of Computer and System Sciences 67 (2003) 757–771."},"date_updated":"2021-01-12T07:41:49Z","extern":1,"type":"journal_article","status":"public","_id":"3209","page":"757 - 771","date_created":"2018-12-11T12:02:01Z","issue":"4","volume":67,"doi":"10.1016/S0022-0000(03)00078-3","date_published":"2003-12-01T00:00:00Z","year":"2003","publication_status":"published","publication":"Journal of Computer and System Sciences","day":"01","publisher":"Elsevier","quality_controlled":0,"intvolume":" 67","month":"12","abstract":[{"text":"We show that the fixed alphabet shortest common supersequence (SCS) and the fixed alphabet longest common subsequence (LCS) problems parameterized in the number of strings are W[1]-hard. Unless W[1]=FPT, this rules out the existence of algorithms with time complexity of O(f(k)nα) for those problems. Here n is the size of the problem instance, α is constant, k is the number of strings and f is any function of k. The fixed alphabet version of the LCS problem is of particular interest considering the importance of sequence comparison (e.g. multiple sequence alignment) in the fixed length alphabet world of DNA and protein sequences.","lang":"eng"}]},{"_id":"3210","conference":{"name":"EUROCRYPT: Theory and Applications of Cryptographic Techniques"},"type":"conference","status":"public","citation":{"chicago":"Maurer, Ueli, and Krzysztof Z Pietrzak. “The Security of Many Round Luby Rackoff Pseudo Random Permutations,” 2656:544–61. Springer, 2003. https://doi.org/10.1007/3-540-39200-9_34.","ista":"Maurer U, Pietrzak KZ. 2003. The security of many round Luby Rackoff pseudo random permutations. EUROCRYPT: Theory and Applications of Cryptographic Techniques, LNCS, vol. 2656, 544–561.","mla":"Maurer, Ueli, and Krzysztof Z. Pietrzak. The Security of Many Round Luby Rackoff Pseudo Random Permutations. Vol. 2656, Springer, 2003, pp. 544–61, doi:10.1007/3-540-39200-9_34.","apa":"Maurer, U., & Pietrzak, K. Z. (2003). The security of many round Luby Rackoff pseudo random permutations (Vol. 2656, pp. 544–561). Presented at the EUROCRYPT: Theory and Applications of Cryptographic Techniques, Springer. https://doi.org/10.1007/3-540-39200-9_34","ama":"Maurer U, Pietrzak KZ. The security of many round Luby Rackoff pseudo random permutations. In: Vol 2656. Springer; 2003:544-561. doi:10.1007/3-540-39200-9_34","short":"U. Maurer, K.Z. Pietrzak, in:, Springer, 2003, pp. 544–561.","ieee":"U. Maurer and K. Z. Pietrzak, “The security of many round Luby Rackoff pseudo random permutations,” presented at the EUROCRYPT: Theory and Applications of Cryptographic Techniques, 2003, vol. 2656, pp. 544–561."},"date_updated":"2021-01-12T07:41:49Z","extern":1,"publist_id":"3473","author":[{"first_name":"Ueli","full_name":"Maurer, Ueli M","last_name":"Maurer"},{"first_name":"Krzysztof Z","id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87","last_name":"Pietrzak","full_name":"Krzysztof Pietrzak","orcid":"0000-0002-9139-1654"}],"title":"The security of many round Luby Rackoff pseudo random permutations","abstract":[{"text":"Luby and Rackoff showed how to construct a (super-)pseudo-random permutation {0,1}2n→ {0,1}2n from some number r of pseudo-random functions {0,1}n → {0,1}n. Their construction, motivated by DES, consists of a cascade of r Feistel permutations. A Feistel permutation 1for a pseudo-random function f is defined as (L, R) → (R,L ⊕ f (R)), where L and R are the left and right part of the input and ⊕ denotes bitwise XOR or, in this paper, any other group operation on {0,1}n. The only non-trivial step of the security proof consists of proving that the cascade of r Feistel permutations with independent uniform random functions {0,1}n → {0,1}n, denoted Ψ2nr is indistinguishable from a uniform random permutation {0,1}2n → {0,1}2n by any computationally unbounded adaptive distinguisher making at most O(2cn) combined chosen plaintext/ciphertext queries for any c < α, where a is a security parameter. Luby and Rackoff proved α = 1/2 for r = 4. A natural problem, proposed by Pieprzyk is to improve on α for larger r. The best known result, α = 3/4 for r = 6, is due to Patarin. In this paper we prove a = 1 -O(1/r), i.e., the trivial upper bound α = 1 can be approached. The proof uses some new techniques that can be of independent interest. ","lang":"eng"}],"publisher":"Springer","alternative_title":["LNCS"],"quality_controlled":0,"intvolume":" 2656","month":"06","year":"2003","publication_status":"published","day":"04","page":"544 - 561","date_created":"2018-12-11T12:02:02Z","date_published":"2003-06-04T00:00:00Z","volume":2656,"doi":"10.1007/3-540-39200-9_34"},{"alternative_title":["Nato Science Series II"],"publisher":"Springer","intvolume":" 166","month":"01","oa_version":"None","page":"277 - 288","date_created":"2018-12-11T12:03:16Z","date_published":"2003-01-01T00:00:00Z","doi":"10.1007/978-1-4020-2705-5_21","volume":166,"year":"2003","publication_status":"published","language":[{"iso":"eng"}],"day":"01","conference":{"name":"NATO ASI on Structure and Dynamics of Elementary Matter"},"type":"conference","status":"public","_id":"3425","article_processing_charge":"No","author":[{"full_name":"Bollenbach, Mark Tobias","orcid":"0000-0003-4398-476X","last_name":"Bollenbach","id":"3E6DB97A-F248-11E8-B48F-1D18A9856A87","first_name":"Mark Tobias"},{"last_name":"Strother","full_name":"Strother, T.","first_name":"T."},{"first_name":"Wolfgang","last_name":"Bauer","full_name":"Bauer, Wolfgang"}],"publist_id":"2976","title":"3D supernova collapse calculations","date_updated":"2021-01-12T07:43:23Z","citation":{"chicago":"Bollenbach, Mark Tobias, T. Strother, and Wolfgang Bauer. “3D Supernova Collapse Calculations,” 166:277–88. Springer, 2003. https://doi.org/10.1007/978-1-4020-2705-5_21.","ista":"Bollenbach MT, Strother T, Bauer W. 2003. 3D supernova collapse calculations. NATO ASI on Structure and Dynamics of Elementary Matter, Nato Science Series II, vol. 166, 277–288.","mla":"Bollenbach, Mark Tobias, et al. 3D Supernova Collapse Calculations. Vol. 166, Springer, 2003, pp. 277–88, doi:10.1007/978-1-4020-2705-5_21.","apa":"Bollenbach, M. T., Strother, T., & Bauer, W. (2003). 3D supernova collapse calculations (Vol. 166, pp. 277–288). Presented at the NATO ASI on Structure and Dynamics of Elementary Matter, Springer. https://doi.org/10.1007/978-1-4020-2705-5_21","ama":"Bollenbach MT, Strother T, Bauer W. 3D supernova collapse calculations. In: Vol 166. Springer; 2003:277-288. doi:10.1007/978-1-4020-2705-5_21","short":"M.T. Bollenbach, T. Strother, W. Bauer, in:, Springer, 2003, pp. 277–288.","ieee":"M. T. Bollenbach, T. Strother, and W. Bauer, “3D supernova collapse calculations,” presented at the NATO ASI on Structure and Dynamics of Elementary Matter, 2003, vol. 166, pp. 277–288."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","extern":"1"},{"year":"2003","publication_status":"published","day":"01","publication":"Lehrbuch Vorklinik","page":"3 - 26","volume":"B","date_published":"2003-01-01T00:00:00Z","date_created":"2018-12-11T12:03:26Z","quality_controlled":0,"publisher":"Deutscher Ärzte Verlag","month":"01","citation":{"mla":"Jonas, Peter M., and Klaus Unsicker. “Molekulare Und Zelluläre Grundlagen Des Nervensystems.” Lehrbuch Vorklinik, edited by R. Schmidt, vol. B, Deutscher Ärzte Verlag, 2003, pp. 3–26.","short":"P.M. Jonas, K. Unsicker, in:, R. Schmidt (Ed.), Lehrbuch Vorklinik, Deutscher Ärzte Verlag, 2003, pp. 3–26.","ieee":"P. M. Jonas and K. Unsicker, “Molekulare und zelluläre Grundlagen des Nervensystems.,” in Lehrbuch Vorklinik, vol. B, R. Schmidt, Ed. Deutscher Ärzte Verlag, 2003, pp. 3–26.","apa":"Jonas, P. M., & Unsicker, K. (2003). Molekulare und zelluläre Grundlagen des Nervensystems. In R. Schmidt (Ed.), Lehrbuch Vorklinik (Vol. B, pp. 3–26). Deutscher Ärzte Verlag.","ama":"Jonas PM, Unsicker K. Molekulare und zelluläre Grundlagen des Nervensystems. In: Schmidt R, ed. Lehrbuch Vorklinik. Vol B. Deutscher Ärzte Verlag; 2003:3-26.","chicago":"Jonas, Peter M, and Klaus Unsicker. “Molekulare Und Zelluläre Grundlagen Des Nervensystems.” In Lehrbuch Vorklinik, edited by R. Schmidt, B:3–26. Deutscher Ärzte Verlag, 2003.","ista":"Jonas PM, Unsicker K. 2003.Molekulare und zelluläre Grundlagen des Nervensystems. In: Lehrbuch Vorklinik. vol. B, 3–26."},"date_updated":"2021-01-12T07:43:35Z","extern":1,"author":[{"id":"353C1B58-F248-11E8-B48F-1D18A9856A87","first_name":"Peter M","orcid":"0000-0001-5001-4804","full_name":"Peter Jonas","last_name":"Jonas"},{"full_name":"Unsicker, Klaus","last_name":"Unsicker","first_name":"Klaus"}],"publist_id":"2929","title":"Molekulare und zelluläre Grundlagen des Nervensystems.","editor":[{"first_name":"R.","last_name":"Schmidt","full_name":"Schmidt, R. F."}],"_id":"3458","type":"book_chapter","status":"public"},{"status":"public","type":"journal_article","_id":"3536","title":"Hippocampal network patterns of activity in the mouse","publist_id":"2849","author":[{"last_name":"Buzsáki","full_name":"Buzsáki, György","first_name":"György"},{"full_name":"Buhl, Derek L","last_name":"Buhl","first_name":"Derek"},{"first_name":"Kenneth","last_name":"Harris","full_name":"Harris, Kenneth D"},{"orcid":"0000-0002-5193-4036","full_name":"Jozsef Csicsvari","last_name":"Csicsvari","first_name":"Jozsef L","id":"3FA14672-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Boldizsár","last_name":"Czéh","full_name":"Czéh, Boldizsár"},{"first_name":"Alexei","full_name":"Morozov, Alexei","last_name":"Morozov"}],"extern":1,"date_updated":"2021-01-12T07:44:09Z","citation":{"chicago":"Buzsáki, György, Derek Buhl, Kenneth Harris, Jozsef L Csicsvari, Boldizsár Czéh, and Alexei Morozov. “Hippocampal Network Patterns of Activity in the Mouse.” Neuroscience. Elsevier, 2003. https://doi.org/10.1016/S0306-4522(02)00669-3.","ista":"Buzsáki G, Buhl D, Harris K, Csicsvari JL, Czéh B, Morozov A. 2003. Hippocampal network patterns of activity in the mouse. Neuroscience. 116(1), 201–211.","mla":"Buzsáki, György, et al. “Hippocampal Network Patterns of Activity in the Mouse.” Neuroscience, vol. 116, no. 1, Elsevier, 2003, pp. 201–11, doi:10.1016/S0306-4522(02)00669-3.","ieee":"G. Buzsáki, D. Buhl, K. Harris, J. L. Csicsvari, B. Czéh, and A. Morozov, “Hippocampal network patterns of activity in the mouse,” Neuroscience, vol. 116, no. 1. Elsevier, pp. 201–211, 2003.","short":"G. Buzsáki, D. Buhl, K. Harris, J.L. Csicsvari, B. Czéh, A. Morozov, Neuroscience 116 (2003) 201–211.","ama":"Buzsáki G, Buhl D, Harris K, Csicsvari JL, Czéh B, Morozov A. Hippocampal network patterns of activity in the mouse. Neuroscience. 2003;116(1):201-211. doi:10.1016/S0306-4522(02)00669-3","apa":"Buzsáki, G., Buhl, D., Harris, K., Csicsvari, J. L., Czéh, B., & Morozov, A. (2003). Hippocampal network patterns of activity in the mouse. Neuroscience. Elsevier. https://doi.org/10.1016/S0306-4522(02)00669-3"},"intvolume":" 116","month":"01","publisher":"Elsevier","quality_controlled":0,"abstract":[{"lang":"eng","text":"Genetic engineering of the mouse brain allows investigators to address novel hypotheses in vivo. Because of the paucity of information on the network patterns of the mouse hippocampus, we investigated the electrical patterns in the behaving animal using multisite silicon probes and wire tetrodes. Theta (6-9 Hz) and gamma (40-100 Hz) oscillations were present during exploration and rapid eye movement sleep. Gamma power and theta power were comodulated and gamma power varied as a function of the theta cycle. Pyramidal cells and putative interneurons were phase-locked to theta oscillations. During immobility, consummatory behaviors and slow-wave sleep, sharp waves were present in cornu ammonis region CA1 of the hippocampus stratum radiatum associated with 140-200-Hz “ripples” in the pyramidal cell layer and population burst of CA1 neurons. In the hilus, large-amplitude “dentate spikes” occurred in association with increased discharge of hilar neurons. The amplitude of field patterns was larger in the mouse than in the rat, likely reflecting the higher neuron density in a smaller brain. We suggest that the main hippocampal network patterns are mediated by similar pathways and mechanisms in mouse and rat. "}],"date_created":"2018-12-11T12:03:50Z","issue":"1","date_published":"2003-01-15T00:00:00Z","volume":116,"doi":"10.1016/S0306-4522(02)00669-3","page":"201 - 211","publication":"Neuroscience","day":"15","year":"2003","publication_status":"published"},{"publist_id":"2829","author":[{"orcid":"0000-0002-9823-6833","full_name":"Herbert Edelsbrunner","last_name":"Edelsbrunner","first_name":"Herbert","id":"3FB178DA-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Harer, John","last_name":"Harer","first_name":"John"},{"full_name":"Natarajan, Vijay","last_name":"Natarajan","first_name":"Vijay"},{"full_name":"Pascucci, Valerio","last_name":"Pascucci","first_name":"Valerio"}],"title":"Morse-Smale complexes for piecewise linear 3-manifolds","citation":{"ama":"Edelsbrunner H, Harer J, Natarajan V, Pascucci V. Morse-Smale complexes for piecewise linear 3-manifolds. In: ACM; 2003:361-370. doi:10.1145/777792.777846","apa":"Edelsbrunner, H., Harer, J., Natarajan, V., & Pascucci, V. (2003). Morse-Smale complexes for piecewise linear 3-manifolds (pp. 361–370). Presented at the SCG: Symposium on Computational Geometry, ACM. https://doi.org/10.1145/777792.777846","short":"H. Edelsbrunner, J. Harer, V. Natarajan, V. Pascucci, in:, ACM, 2003, pp. 361–370.","ieee":"H. Edelsbrunner, J. Harer, V. Natarajan, and V. Pascucci, “Morse-Smale complexes for piecewise linear 3-manifolds,” presented at the SCG: Symposium on Computational Geometry, 2003, pp. 361–370.","mla":"Edelsbrunner, Herbert, et al. Morse-Smale Complexes for Piecewise Linear 3-Manifolds. ACM, 2003, pp. 361–70, doi:10.1145/777792.777846.","ista":"Edelsbrunner H, Harer J, Natarajan V, Pascucci V. 2003. Morse-Smale complexes for piecewise linear 3-manifolds. SCG: Symposium on Computational Geometry, 361–370.","chicago":"Edelsbrunner, Herbert, John Harer, Vijay Natarajan, and Valerio Pascucci. “Morse-Smale Complexes for Piecewise Linear 3-Manifolds,” 361–70. ACM, 2003. https://doi.org/10.1145/777792.777846."},"date_updated":"2021-01-12T07:44:17Z","extern":1,"conference":{"name":"SCG: Symposium on Computational Geometry"},"type":"conference","status":"public","_id":"3556","page":"361 - 370","date_created":"2018-12-11T12:03:57Z","date_published":"2003-06-01T00:00:00Z","doi":"10.1145/777792.777846","publication_status":"published","year":"2003","day":"01","main_file_link":[{"url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.14.9592","open_access":"0"}],"quality_controlled":0,"publisher":"ACM","month":"06","abstract":[{"lang":"eng","text":"We define the Morse-Smale complex of a Morse function over a 3-manifold as the overlay of the descending and as- cending manifolds of all critical points. In the generic case, its 3-dimensional cells are shaped like crystals and are sepa- rated by quadrangular faces. In this paper, we give a combi- natorial algorithm for constructing such complexes for piece- wise linear data."}]},{"main_file_link":[{"open_access":"0","url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.129.3633"}],"publisher":"Springer","quality_controlled":0,"month":"06","abstract":[{"text":"Given a finite point set in R, the surface reconstruction problem asks for a surface that passes through many but not necessarily all points. We describe an unambigu- ous definition of such a surface in geometric and topological terms, and sketch a fast algorithm for constructing it. Our solution overcomes past limitations to special point distributions and heuristic design decisions.","lang":"eng"}],"page":"379 - 404","date_created":"2018-12-11T12:04:02Z","doi":"10.1007/978-3-642-55566-4_17","date_published":"2003-06-23T00:00:00Z","year":"2003","publication_status":"published","publication":"Discrete & Computational Geometry","day":"23","type":"book_chapter","status":"public","_id":"3573","publist_id":"2812","author":[{"first_name":"Herbert","id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","last_name":"Edelsbrunner","full_name":"Herbert Edelsbrunner","orcid":"0000-0002-9823-6833"}],"title":"Surface reconstruction by wrapping finite sets in space","citation":{"mla":"Edelsbrunner, Herbert. “Surface Reconstruction by Wrapping Finite Sets in Space.” Discrete & Computational Geometry, Springer, 2003, pp. 379–404, doi:10.1007/978-3-642-55566-4_17.","apa":"Edelsbrunner, H. (2003). Surface reconstruction by wrapping finite sets in space. In Discrete & Computational Geometry (pp. 379–404). Springer. https://doi.org/10.1007/978-3-642-55566-4_17","ama":"Edelsbrunner H. Surface reconstruction by wrapping finite sets in space. In: Discrete & Computational Geometry. Springer; 2003:379-404. doi:10.1007/978-3-642-55566-4_17","ieee":"H. Edelsbrunner, “Surface reconstruction by wrapping finite sets in space,” in Discrete & Computational Geometry, Springer, 2003, pp. 379–404.","short":"H. Edelsbrunner, in:, Discrete & Computational Geometry, Springer, 2003, pp. 379–404.","chicago":"Edelsbrunner, Herbert. “Surface Reconstruction by Wrapping Finite Sets in Space.” In Discrete & Computational Geometry, 379–404. Springer, 2003. https://doi.org/10.1007/978-3-642-55566-4_17.","ista":"Edelsbrunner H. 2003.Surface reconstruction by wrapping finite sets in space. In: Discrete & Computational Geometry. , 379–404."},"date_updated":"2021-01-12T07:44:24Z","extern":1}]