@inproceedings{3425, author = {Bollenbach, Mark Tobias and Strother, T. and Bauer, Wolfgang}, pages = {277 -- 288}, publisher = {Springer}, title = {{3D supernova collapse calculations}}, doi = {10.1007/978-1-4020-2705-5_21}, volume = {166}, year = {2003}, } @inbook{3458, author = {Peter Jonas and Unsicker, Klaus}, booktitle = {Lehrbuch Vorklinik}, editor = {Schmidt, R. F.}, pages = {3 -- 26}, publisher = {Deutscher Ärzte Verlag}, title = {{Molekulare und zelluläre Grundlagen des Nervensystems.}}, volume = {B}, year = {2003}, } @article{3536, abstract = {Genetic engineering of the mouse brain allows investigators to address novel hypotheses in vivo. Because of the paucity of information on the network patterns of the mouse hippocampus, we investigated the electrical patterns in the behaving animal using multisite silicon probes and wire tetrodes. Theta (6-9 Hz) and gamma (40-100 Hz) oscillations were present during exploration and rapid eye movement sleep. Gamma power and theta power were comodulated and gamma power varied as a function of the theta cycle. Pyramidal cells and putative interneurons were phase-locked to theta oscillations. During immobility, consummatory behaviors and slow-wave sleep, sharp waves were present in cornu ammonis region CA1 of the hippocampus stratum radiatum associated with 140-200-Hz “ripples” in the pyramidal cell layer and population burst of CA1 neurons. In the hilus, large-amplitude “dentate spikes” occurred in association with increased discharge of hilar neurons. The amplitude of field patterns was larger in the mouse than in the rat, likely reflecting the higher neuron density in a smaller brain. We suggest that the main hippocampal network patterns are mediated by similar pathways and mechanisms in mouse and rat. }, author = {Buzsáki, György and Buhl, Derek L and Harris, Kenneth D and Jozsef Csicsvari and Czéh, Boldizsár and Morozov, Alexei}, journal = {Neuroscience}, number = {1}, pages = {201 -- 211}, publisher = {Elsevier}, title = {{Hippocampal network patterns of activity in the mouse}}, doi = {10.1016/S0306-4522(02)00669-3}, volume = {116}, year = {2003}, } @inproceedings{3556, abstract = {We define the Morse-Smale complex of a Morse function over a 3-manifold as the overlay of the descending and as- cending manifolds of all critical points. In the generic case, its 3-dimensional cells are shaped like crystals and are sepa- rated by quadrangular faces. In this paper, we give a combi- natorial algorithm for constructing such complexes for piece- wise linear data.}, author = {Herbert Edelsbrunner and Harer, John and Natarajan, Vijay and Pascucci, Valerio}, pages = {361 -- 370}, publisher = {ACM}, title = {{Morse-Smale complexes for piecewise linear 3-manifolds}}, doi = {10.1145/777792.777846}, year = {2003}, } @inbook{3573, abstract = {Given a finite point set in R, the surface reconstruction problem asks for a surface that passes through many but not necessarily all points. We describe an unambigu- ous definition of such a surface in geometric and topological terms, and sketch a fast algorithm for constructing it. Our solution overcomes past limitations to special point distributions and heuristic design decisions.}, author = {Herbert Edelsbrunner}, booktitle = {Discrete & Computational Geometry}, pages = {379 -- 404}, publisher = {Springer}, title = {{Surface reconstruction by wrapping finite sets in space}}, doi = {10.1007/978-3-642-55566-4_17}, year = {2003}, } @article{3584, abstract = {We develop fast algorithms for computing the linking number of a simplicial complex within a filtration.We give experimental results in applying our work toward the detection of non-trivial tangling in biomolecules, modeled as alpha complexes.}, author = {Edelsbrunner, Herbert and Zomorodian, Afra}, journal = {Homology, Homotopy and Applications}, number = {2}, pages = {19 -- 37}, publisher = {International Press}, title = {{Computing linking numbers of a filtration}}, volume = {5}, year = {2003}, } @article{3620, abstract = {Stable hybrid zones in which ecologically divergent taxa give rise to a range of recombinants are natural laboratories in which the genetic basis of adaptation and reproductive isolation can be unraveled. One such hybrid zone is formed by the fire-bellied toads Bombina bombina and B. variegata (Anura: Discoglossidae). Adaptations to permanent and ephemeral breeding habitats, respectively, have shaped numerous phenotypic differences between the taxa. All of these are, in principle, candidates for a genetic dissection via QTL mapping. We present here a linkage map of 28 codominant and 10 dominant markers in the Bombina genome. In an F2 cross, markers that were mainly microsatellites, SSCPs or allozymes were mapped to 20 linkage groups. Among the 40 isolated CA microsatellites, we noted a preponderance of compound and frequently interleaved CA-TA repeats as well as a striking polarity at the 5′ end of the repeats.}, author = {Nürnberger, Beate and Hofman, Sebastian and Förg-Brey, Bqruni and Praetzel, Gabriele and Maclean, Alan W and Szymura, Jacek M and Abbott, Catherine M and Nicholas Barton}, journal = {Heredity}, number = {2}, pages = {136 -- 142}, publisher = {Nature Publishing Group}, title = {{A linkage map for the hybridising toads Bombina bombina and B. variegata (Anura: Discoglossidae)}}, doi = {10.1038/sj.hdy.6800291}, volume = {91}, year = {2003}, } @article{3619, abstract = {What is the chance that some part of a stretch of genome will survive? In a population of constant size, and with no selection, the probability of survival of some part of a stretch of map length y<1 approaches View the MathML source for View the MathML source. Thus, the whole genome is certain to be lost, but the rate of loss is extremely slow. This solution extends to give the whole distribution of surviving block sizes as a function of time. We show that the expected number of blocks at time t is 1+yt and give expressions for the moments of the number of blocks and the total amount of genome that survives for a given time. The solution is based on a branching process and assumes complete interference between crossovers, so that each descendant carries only a single block of ancestral material. We consider cases where most individuals carry multiple blocks, either because there are multiple crossovers in a long genetic map, or because enough time has passed that most individuals in the population are related to each other. For species such as ours, which have a long genetic map, the genome of any individual which leaves descendants (∼80% of the population for a Poisson offspring number with mean two) is likely to persist for an extremely long time, in the form of a few short blocks of genome.}, author = {Baird, Stuart J and Nicholas Barton and Etheridge, Alison M}, journal = {Theoretical Population Biology}, number = {4}, pages = {451 -- 471}, publisher = {Academic Press}, title = {{The distribution of surviving blocks of an ancestral genome}}, doi = {10.1016/S0040-5809(03)00098-4}, volume = {64}, year = {2003}, } @article{3618, abstract = {There are several analyses in evolutionary ecology which assume that a family of offspring has come from only two parents. Here, we present a simple test for detecting when a batch involves two or more subfamilies. It is based on the fact that the mixing of families generates associations amongst unlinked marker loci. We also present simulations illustrating the power of our method for varying numbers of loci, alleles per locus and genotyped individuals.}, author = {Vines, Timothy H and Nicholas Barton}, journal = {Molecular Ecology}, number = {7}, pages = {1999 -- 2002}, publisher = {Wiley-Blackwell}, title = {{A new approach to detecting mixed families}}, doi = {10.1046/j.1365-294X.2003.01867.x}, volume = {12}, year = {2003}, } @article{3752, abstract = {We use the lac operon in Escherichia coli as a prototype system to illustrate the current state, applicability, and limitations of modeling the dynamics of cellular networks. We integrate three different levels of description (molecular, cellular, and that of cell population) into a single model, which seems to capture many experimental aspects of the system.}, author = {Vilar,Jose M and Calin Guet and Leibler, Stanislas}, journal = {Journal of Cell Biology}, number = {3}, pages = {471 -- 476}, publisher = {Rockefeller University Press}, title = {{Modeling network dynamics: the lac operon, a case study}}, doi = {10.1083/jcb.200301125}, volume = {161}, year = {2003}, }