---
_id: '4349'
abstract:
- lang: eng
text: 'Bayesian inference is becoming a common statistical approach to phylogenetic
estimation because, among other reasons, it allows for rapid analysis of large
data sets with complex evolutionary models. Conveniently, Bayesian phylogenetic
methods use currently available stochastic models of sequence evolution. However,
as with other model-based approaches, the results of Bayesian inference are conditional
on the assumed model of evolution: inadequate models (models that poorly fit the
data) may result in erroneous inferences. In this article, I present a Bayesian
phylogenetic method that evaluates the adequacy of evolutionary models using posterior
predictive distributions. By evaluating a model''s posterior predictive performance,
an adequate model can be selected for a Bayesian phylogenetic study. Although
I present a single test statistic that assesses the overall (global) performance
of a phylogenetic model, a variety of test statistics can be tailored to evaluate
specific features (local performance) of evolutionary models to identify sources
failure. The method presented here, unlike the likelihood-ratio test and parametric
bootstrap, accounts for uncertainty in the phylogeny and model parameters.'
acknowledgement: "This work was supported by grants from the NSF to John Huelsenbeck
(MCB-0075404 and DEB0075406), to whom I am grateful for his support throughout this
project. Also, I would like to express my deep thanks to Andrea Betancourt, John
Huelsenbeck, Kelly Dyer, Rasmus Nielsen, and Frederick Ronquist for taking the time
to read early versions of the\r\nmanuscript. Each and every one of them provided
invaluable comments, that ultimately made the manuscript better. John Huelsenbeck,
Bret Larget, Rasmus Nielsen, Ken Karol, and Andrea Betancourt patiently listened
to me drone on about this project, and offered insightful comments that benefited
this work, and for this they have my deepest gratitude. And finally, I would like
to thank two anonymous reviewers who gave critical attention to the manuscript and
provided valuable comments."
article_processing_charge: No
article_type: original
author:
- first_name: Jonathan P
full_name: Bollback, Jonathan P
id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87
last_name: Bollback
orcid: 0000-0002-4624-4612
citation:
ama: Bollback JP. Bayesian model adequacy and choice in phylogenetics. Molecular
Biology and Evolution. 2002;19(7):1171-1180. doi:10.1093/oxfordjournals.molbev.a004175
apa: Bollback, J. P. (2002). Bayesian model adequacy and choice in phylogenetics.
Molecular Biology and Evolution. Oxford University Press. https://doi.org/10.1093/oxfordjournals.molbev.a004175
chicago: Bollback, Jonathan P. “Bayesian Model Adequacy and Choice in Phylogenetics.”
Molecular Biology and Evolution. Oxford University Press, 2002. https://doi.org/10.1093/oxfordjournals.molbev.a004175.
ieee: J. P. Bollback, “Bayesian model adequacy and choice in phylogenetics,” Molecular
Biology and Evolution, vol. 19, no. 7. Oxford University Press, pp. 1171–80,
2002.
ista: Bollback JP. 2002. Bayesian model adequacy and choice in phylogenetics. Molecular
Biology and Evolution. 19(7), 1171–80.
mla: Bollback, Jonathan P. “Bayesian Model Adequacy and Choice in Phylogenetics.”
Molecular Biology and Evolution, vol. 19, no. 7, Oxford University Press,
2002, pp. 1171–80, doi:10.1093/oxfordjournals.molbev.a004175.
short: J.P. Bollback, Molecular Biology and Evolution 19 (2002) 1171–80.
date_created: 2018-12-11T12:08:24Z
date_published: 2002-03-25T00:00:00Z
date_updated: 2023-06-06T09:18:18Z
day: '25'
doi: 10.1093/oxfordjournals.molbev.a004175
extern: '1'
external_id:
pmid:
- '12082136 '
intvolume: ' 19'
issue: '7'
language:
- iso: eng
month: '03'
oa_version: None
page: 1171 - 80
pmid: 1
publication: Molecular Biology and Evolution
publication_identifier:
issn:
- 0737-4038
publication_status: published
publisher: Oxford University Press
publist_id: '1112'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Bayesian model adequacy and choice in phylogenetics
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 19
year: '2002'
...
---
_id: '4263'
abstract:
- lang: eng
text: 'We introduce a general recursion for the probability of identity in state
of two individuals sampled from a population subject to mutation, migration, and
random drift in a two-dimensional continuum. The recursion allows for the interactions
induced by density-dependent regulation of the population, which are inevitable
in a continuous population. We give explicit series expansions for large neighbourhood
size and for low mutation rates respectively and investigate the accuracy of the
classical Malécot formula for these general models. When neighbourhood size is
small, this formula does not give the identity even over large scales. However,
for large neighbourhood size, it is an accurate approximation which summarises
the local population structure in terms of three quantities: the effective dispersal
rate, σe; the effective population density, ρe; and a local scale, κ, at which
local interactions become significant. The results are illustrated by simulations.'
acknowledgement: This work was supported by grants from the EPSRC (GR/L10048 and an
advanced fellowship for A.M.E.) and NERC (GR3/11635) and by the Darwin Trust of
Edinburgh. We thank Anja Sturm for her assistance with the project and anonymous
reviewers for helpful comments. This paper is dedicated to Charlotte, A.M.E.’s daughter
born during the gestation of the manuscript.
article_processing_charge: No
article_type: original
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Frantz
full_name: Depaulis, Frantz
last_name: Depaulis
- first_name: Alison
full_name: Etheridge, Alison
last_name: Etheridge
citation:
ama: Barton NH, Depaulis F, Etheridge A. Neutral evolution in spatially continuous
populations. Theoretical Population Biology. 2002;61(1):31-48. doi:10.1006/tpbi.2001.1557
apa: Barton, N. H., Depaulis, F., & Etheridge, A. (2002). Neutral evolution
in spatially continuous populations. Theoretical Population Biology. Academic
Press. https://doi.org/10.1006/tpbi.2001.1557
chicago: Barton, Nicholas H, Frantz Depaulis, and Alison Etheridge. “Neutral Evolution
in Spatially Continuous Populations.” Theoretical Population Biology. Academic
Press, 2002. https://doi.org/10.1006/tpbi.2001.1557.
ieee: N. H. Barton, F. Depaulis, and A. Etheridge, “Neutral evolution in spatially
continuous populations,” Theoretical Population Biology, vol. 61, no. 1.
Academic Press, pp. 31–48, 2002.
ista: Barton NH, Depaulis F, Etheridge A. 2002. Neutral evolution in spatially continuous
populations. Theoretical Population Biology. 61(1), 31–48.
mla: Barton, Nicholas H., et al. “Neutral Evolution in Spatially Continuous Populations.”
Theoretical Population Biology, vol. 61, no. 1, Academic Press, 2002, pp.
31–48, doi:10.1006/tpbi.2001.1557.
short: N.H. Barton, F. Depaulis, A. Etheridge, Theoretical Population Biology 61
(2002) 31–48.
date_created: 2018-12-11T12:07:55Z
date_published: 2002-02-01T00:00:00Z
date_updated: 2023-06-06T09:57:49Z
day: '01'
doi: 10.1006/tpbi.2001.1557
extern: '1'
external_id:
pmid:
- '11895381'
intvolume: ' 61'
issue: '1'
language:
- iso: eng
month: '02'
oa_version: None
page: 31 - 48
pmid: 1
publication: Theoretical Population Biology
publication_identifier:
issn:
- 0040-5809
publication_status: published
publisher: Academic Press
publist_id: '1830'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Neutral evolution in spatially continuous populations
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 61
year: '2002'
...
---
_id: '4261'
abstract:
- lang: eng
text: Until recently, it was impracticable to identify the genes that are responsible
for variation in continuous traits, or to directly observe the effects of their
different alleles. Now, the abundance of genetic markers has made it possible
to identify quantitative trait loci (QTL) — the regions of a chromosome or, ideally,
individual sequence variants that are responsible for trait variation. What kind
of QTL do we expect to find and what can our observations of QTL tell us about
how organisms evolve? The key to understanding the evolutionary significance of
QTL is to understand the nature of inherited variation, not in the immediate mechanistic
sense of how genes influence phenotype, but, rather, to know what evolutionary
forces maintain genetic variability.
article_processing_charge: No
article_type: original
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Peter
full_name: Keightley, Peter
last_name: Keightley
citation:
ama: Barton NH, Keightley P. Understanding quantitative genetic variation. Nature
Reviews Genetics. 2002;3:11-21. doi:10.1038/nrg700
apa: Barton, N. H., & Keightley, P. (2002). Understanding quantitative genetic
variation. Nature Reviews Genetics. Nature Publishing Group. https://doi.org/10.1038/nrg700
chicago: Barton, Nicholas H, and Peter Keightley. “Understanding Quantitative Genetic
Variation.” Nature Reviews Genetics. Nature Publishing Group, 2002. https://doi.org/10.1038/nrg700.
ieee: N. H. Barton and P. Keightley, “Understanding quantitative genetic variation,”
Nature Reviews Genetics, vol. 3. Nature Publishing Group, pp. 11–21, 2002.
ista: Barton NH, Keightley P. 2002. Understanding quantitative genetic variation.
Nature Reviews Genetics. 3, 11–21.
mla: Barton, Nicholas H., and Peter Keightley. “Understanding Quantitative Genetic
Variation.” Nature Reviews Genetics, vol. 3, Nature Publishing Group, 2002,
pp. 11–21, doi:10.1038/nrg700.
short: N.H. Barton, P. Keightley, Nature Reviews Genetics 3 (2002) 11–21.
date_created: 2018-12-11T12:07:55Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-06-06T10:07:00Z
day: '01'
doi: 10.1038/nrg700
extern: '1'
external_id:
pmid:
- '11823787'
intvolume: ' 3'
language:
- iso: eng
month: '01'
oa_version: None
page: 11 - 21
pmid: 1
publication: Nature Reviews Genetics
publication_identifier:
issn:
- 1471-0056
publication_status: published
publisher: Nature Publishing Group
publist_id: '1831'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Understanding quantitative genetic variation
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 3
year: '2002'
...
---
_id: '4347'
abstract:
- lang: eng
text: 'Phylogenetic trees can be rooted by a number of criteria. Here, we introduce
a Bayesian method for inferring the root of a phylogenetic tree by using one of
several criteria: the outgroup, molecular clock, and nonreversible model of DNA
substitution. We perform simulation analyses to examine the relative ability of
these three criteria to correctly identify the root of the tree. The outgroup
and molecular clock criteria were best able to identify the root of the tree,
whereas the nonreversible model was able to identify the root only when the substitution
process was highly nonreversible. We also examined the performance of the criteria
for a tree of four species for which the topology and root position are well supported.
Results of the analyses of these data are consistent with the simulation results.'
article_processing_charge: No
article_type: original
author:
- first_name: John
full_name: Huelsenbeck, John
last_name: Huelsenbeck
- first_name: Jonathan P
full_name: Bollback, Jonathan P
id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87
last_name: Bollback
orcid: 0000-0002-4624-4612
- first_name: Amy
full_name: Levine, Amy
last_name: Levine
citation:
ama: Huelsenbeck J, Bollback JP, Levine A. Inferring the root of a phylogenetic
tree. Systematic Biology. 2002;51(1):32-43. doi:10.1080/106351502753475862
apa: Huelsenbeck, J., Bollback, J. P., & Levine, A. (2002). Inferring the root
of a phylogenetic tree. Systematic Biology. Oxford University Press. https://doi.org/10.1080/106351502753475862
chicago: Huelsenbeck, John, Jonathan P Bollback, and Amy Levine. “Inferring the
Root of a Phylogenetic Tree.” Systematic Biology. Oxford University Press,
2002. https://doi.org/10.1080/106351502753475862.
ieee: J. Huelsenbeck, J. P. Bollback, and A. Levine, “Inferring the root of a phylogenetic
tree,” Systematic Biology, vol. 51, no. 1. Oxford University Press, pp.
32–43, 2002.
ista: Huelsenbeck J, Bollback JP, Levine A. 2002. Inferring the root of a phylogenetic
tree. Systematic Biology. 51(1), 32–43.
mla: Huelsenbeck, John, et al. “Inferring the Root of a Phylogenetic Tree.” Systematic
Biology, vol. 51, no. 1, Oxford University Press, 2002, pp. 32–43, doi:10.1080/106351502753475862.
short: J. Huelsenbeck, J.P. Bollback, A. Levine, Systematic Biology 51 (2002) 32–43.
date_created: 2018-12-11T12:08:23Z
date_published: 2002-02-01T00:00:00Z
date_updated: 2023-06-06T09:53:27Z
day: '01'
doi: 10.1080/106351502753475862
extern: '1'
external_id:
pmid:
- '11943091'
intvolume: ' 51'
issue: '1'
language:
- iso: eng
month: '02'
oa_version: None
page: 32 - 43
pmid: 1
publication: Systematic Biology
publication_identifier:
issn:
- 0039-7989
publication_status: published
publisher: Oxford University Press
publist_id: '1113'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Inferring the root of a phylogenetic tree
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 51
year: '2002'
...
---
_id: '4407'
abstract:
- lang: eng
text: 'This paper presents a complete axiomatization of two decidable propositional
real-time linear temporal logics: Event Clock Logic (EventClockTL) and Metric
Interval Temporal Logic with past (MetricIntervalTL). The completeness proof consists
of an effective proof building procedure for EventClockTL. From this result we
obtain a complete axiomatization of MetricIntervalTL by providing axioms translating
MetricIntervalTL formulae into EventClockTL formulae, the two logics being equally
expressive. Our proof is structured to yield axiomatizations also for interesting
fragments of these logics, such as the linear temporal logic of the real numbers
(TLR).'
article_processing_charge: No
article_type: original
author:
- first_name: Jean
full_name: Raskin, Jean
last_name: Raskin
- first_name: Pierre
full_name: Schobbens, Pierre
last_name: Schobbens
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
citation:
ama: Raskin J, Schobbens P, Henzinger TA. Axioms for real-time logics. Theoretical
Computer Science. 2002;274(1-2):151-182. doi:10.1016/S0304-3975(00)00308-X
apa: Raskin, J., Schobbens, P., & Henzinger, T. A. (2002). Axioms for real-time
logics. Theoretical Computer Science. Elsevier. https://doi.org/10.1016/S0304-3975(00)00308-X
chicago: Raskin, Jean, Pierre Schobbens, and Thomas A Henzinger. “Axioms for Real-Time
Logics.” Theoretical Computer Science. Elsevier, 2002. https://doi.org/10.1016/S0304-3975(00)00308-X.
ieee: J. Raskin, P. Schobbens, and T. A. Henzinger, “Axioms for real-time logics,”
Theoretical Computer Science, vol. 274, no. 1–2. Elsevier, pp. 151–182,
2002.
ista: Raskin J, Schobbens P, Henzinger TA. 2002. Axioms for real-time logics. Theoretical
Computer Science. 274(1–2), 151–182.
mla: Raskin, Jean, et al. “Axioms for Real-Time Logics.” Theoretical Computer
Science, vol. 274, no. 1–2, Elsevier, 2002, pp. 151–82, doi:10.1016/S0304-3975(00)00308-X.
short: J. Raskin, P. Schobbens, T.A. Henzinger, Theoretical Computer Science 274
(2002) 151–182.
date_created: 2018-12-11T12:08:42Z
date_published: 2002-03-01T00:00:00Z
date_updated: 2023-06-06T09:10:56Z
day: '01'
doi: 10.1016/S0304-3975(00)00308-X
extern: '1'
intvolume: ' 274'
issue: 1-2
language:
- iso: eng
month: '03'
oa_version: None
page: 151 - 182
publication: Theoretical Computer Science
publication_identifier:
issn:
- 0304-3975
publication_status: published
publisher: Elsevier
publist_id: '324'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Axioms for real-time logics
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 274
year: '2002'
...
---
_id: '4258'
abstract:
- lang: eng
text: We studied the effect of multilocus balancing selection on neutral nucleotide
variability at linked sites by simulating a model where diallelic polymorphisms
are maintained at an arbitrary number of selected loci by means of symmetric overdominance.
Different combinations of alleles define different genetic backgrounds that subdivide
the population and strongly affect variability. Several multilocus fitness regimes
with different degrees of epistasis and gametic disequilibrium are allowed. Analytical
results based on a multilocus extension of the structured coalescent predict that
the expected linked neutral diversity increases exponentially with the number
of selected loci and can become extremely large. Our simulation results show that
although variability increases with the number of genetic backgrounds that are
maintained in the population, it is reduced by random fluctuations in the frequencies
of those backgrounds and does not reach high levels even in very large populations.
We also show that previous results on balancing selection in single-locus systems
do not extend to the multilocus scenario in a straightforward way. Different patterns
of linkage disequilibrium and of the frequency spectrum of neutral mutations are
expected under different degrees of epistasis. Interestingly, the power to detect
balancing selection using deviations from a neutral distribution of allele frequencies
seems to be diminished under the fitness regime that leads to the largest increase
of variability over the neutral case. This and other results are discussed in
the light of data from the Mhc.
acknowledgement: We thank P. Andolfatto, P. Awadalla, B. Charlesworth, D. Charles-
Guillaudeux, T., M. Janer, G. K. S. Wong, T. Spies and D. E. Geraghty, F. Depaulis,
S. Otto, J. Rozas, and three anonymous reviewers for valuable discussion and criticism.
A.N. is grateful to F. Depaulis, whose comments were particularly helpful (and extremely
funny), and to D. Charlesworth, whose ideas made this work readable. This work was
supported by Biotechnology and Biological Sciences Research Council/Engineering
and Physical Sciences Research Council.
article_processing_charge: No
article_type: original
author:
- first_name: Arcadio
full_name: Navarro, Arcadio
last_name: Navarro
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Navarro A, Barton NH. The effects of multilocus balancing selection on neutral
variability. Genetics. 2002;161(2):849-863. doi:10.1093/genetics/161.2.849
apa: Navarro, A., & Barton, N. H. (2002). The effects of multilocus balancing
selection on neutral variability. Genetics. Genetics Society of America.
https://doi.org/10.1093/genetics/161.2.849
chicago: Navarro, Arcadio, and Nicholas H Barton. “The Effects of Multilocus Balancing
Selection on Neutral Variability.” Genetics. Genetics Society of America,
2002. https://doi.org/10.1093/genetics/161.2.849.
ieee: A. Navarro and N. H. Barton, “The effects of multilocus balancing selection
on neutral variability,” Genetics, vol. 161, no. 2. Genetics Society of
America, pp. 849–863, 2002.
ista: Navarro A, Barton NH. 2002. The effects of multilocus balancing selection
on neutral variability. Genetics. 161(2), 849–863.
mla: Navarro, Arcadio, and Nicholas H. Barton. “The Effects of Multilocus Balancing
Selection on Neutral Variability.” Genetics, vol. 161, no. 2, Genetics
Society of America, 2002, pp. 849–63, doi:10.1093/genetics/161.2.849.
short: A. Navarro, N.H. Barton, Genetics 161 (2002) 849–863.
date_created: 2018-12-11T12:07:53Z
date_published: 2002-06-01T00:00:00Z
date_updated: 2023-06-06T12:02:32Z
day: '01'
doi: 10.1093/genetics/161.2.849
extern: '1'
external_id:
pmid:
- '12072479'
intvolume: ' 161'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462137/
month: '06'
oa: 1
oa_version: Published Version
page: 849 - 863
pmid: 1
publication: Genetics
publication_identifier:
issn:
- 0016-6731
publication_status: published
publisher: Genetics Society of America
publist_id: '1835'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The effects of multilocus balancing selection on neutral variability
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 161
year: '2002'
...
---
_id: '4259'
abstract:
- lang: eng
text: 'We extend current multilocus models to describe the effects of migration,
recombination, selection, and nonrandom mating on sets of genes in diploids with
varied modes of inheritance, allowing us to consider the patterns of nuclear and
cytonuclear associations (disequilibria) under various models of migration. We
show the relationship between the multilocus notation recently presented by Kirkpatrick,
Johnson, and Barton (developed from previous work by Barton and Turelli) and the
cytonuclear parameterization of Asmussen, Arnold, and Avise and extend this notation
to describe associations between cytoplasmic elements and multiple nuclear genes.
Under models with sexual symmetry, both nuclear-nuclear and cytonuclear disequilibria
are equivalent. They differ, however, in cases involving some type of sexual asymmetry,
which is then reflected in the asymmetric inheritance of cytoplasmic markers.
An example given is the case of different migration rates in males and females;
simulations using 2, 3, 4, or 5 unlinked autosomal markers with a maternally inherited
cytoplasmic marker illustrate how nuclear-nuclear and cytonuclear associations
can be used to separately estimate female and male migration rates. The general
framework developed here allows us to investigate conditions where associations
between loci with different modes of inheritance are not equivalent and to use
this nonequivalence to test for deviations from simple models of admixture. '
acknowledgement: The authors thank Toby Johnson for his helpful comments on this manuscript.
This work was supported by a National Science Foundation NATO postdoctoral fellowship
and National Science Foundation grants DEB-9813335 and DEB-0108242 to M.E.O.; N.H.B.
gratefully acknowledges the support of the Darwin Trust of Edinburgh and the National
Environmental Research Council.
article_processing_charge: No
article_type: original
author:
- first_name: Maria
full_name: Orive, Maria
last_name: Orive
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Orive M, Barton NH. Associations between cytoplasmic and nuclear loci in hybridizing
populations. Genetics. 2002;162(3):1469-1485. doi:10.1093/genetics/162.3.1469
apa: Orive, M., & Barton, N. H. (2002). Associations between cytoplasmic and
nuclear loci in hybridizing populations. Genetics. Genetics Society of
America. https://doi.org/10.1093/genetics/162.3.1469
chicago: Orive, Maria, and Nicholas H Barton. “Associations between Cytoplasmic
and Nuclear Loci in Hybridizing Populations.” Genetics. Genetics Society
of America, 2002. https://doi.org/10.1093/genetics/162.3.1469.
ieee: M. Orive and N. H. Barton, “Associations between cytoplasmic and nuclear loci
in hybridizing populations,” Genetics, vol. 162, no. 3. Genetics Society
of America, pp. 1469–1485, 2002.
ista: Orive M, Barton NH. 2002. Associations between cytoplasmic and nuclear loci
in hybridizing populations. Genetics. 162(3), 1469–1485.
mla: Orive, Maria, and Nicholas H. Barton. “Associations between Cytoplasmic and
Nuclear Loci in Hybridizing Populations.” Genetics, vol. 162, no. 3, Genetics
Society of America, 2002, pp. 1469–85, doi:10.1093/genetics/162.3.1469.
short: M. Orive, N.H. Barton, Genetics 162 (2002) 1469–1485.
date_created: 2018-12-11T12:07:54Z
date_published: 2002-11-01T00:00:00Z
date_updated: 2023-06-06T12:19:54Z
day: '01'
doi: 10.1093/genetics/162.3.1469
extern: '1'
external_id:
pmid:
- '12454089'
intvolume: ' 162'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462324/
month: '11'
oa: 1
oa_version: Published Version
page: 1469 - 1485
pmid: 1
publication: Genetics
publication_identifier:
issn:
- 0016-6731
publication_status: published
publisher: Genetics Society of America
publist_id: '1836'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Associations between cytoplasmic and nuclear loci in hybridizing populations
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 162
year: '2002'
...
---
_id: '4209'
abstract:
- lang: eng
text: We have identified widerborst (wdb), a B' regulatory subunit of PP2A, as a
conserved component of planar cell polarization mechanisms in both Drosophila
and in zebrafish. In Drosophila, wdb acts at two steps during planar polarization
of wing epithelial cells. It is required to organize tissue polarity proteins
into proximal and distal cortical domains, thus determining wing hair orientation.
It is also needed to generate the polarized membrane outgrowth that becomes the
wing hair. Widerborst activates the catalytic subunit of PP2A and localizes to
the distal side of a planar microtubule web that lies at the level of apical cell
junctions. This suggests that polarized PP2A activation along the planar microtubule
web is important for planar polarization. In zebrafish, two wdb homologs are required
for convergent extension during gastrulation, supporting the conjecture that Drosophila
planar cell polarization and vertebrate gastrulation movements are regulated by
similar mechanisms.
acknowledgement: We gratefully acknowledge Bianca Habermann for assistance with bioinformatics,
Jens Rietdorf and Arshad Desai for help with deconvolution, and Tadashi Uemura and
Rick Fehon for providing antibodies. Arshad Desai, Christian Dahmann, Tony Hyman
and Elly Tanaka provided helpful comments on the manuscript. Part of this work was
performed at the EMBL in Heidelberg.
article_processing_charge: No
article_type: original
author:
- first_name: Michael
full_name: Hannus, Michael
last_name: Hannus
- first_name: Fabian
full_name: Feiguin, Fabian
last_name: Feiguin
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Suzanne
full_name: Eaton, Suzanne
last_name: Eaton
citation:
ama: Hannus M, Feiguin F, Heisenberg C-PJ, Eaton S. Planar cell polarization requires
Widerborst, a B′ regulatory subunit of protein phosphatase 2A. Development.
2002;129(14):3493-3503. doi:10.1242/dev.129.14.3493
apa: Hannus, M., Feiguin, F., Heisenberg, C.-P. J., & Eaton, S. (2002). Planar
cell polarization requires Widerborst, a B′ regulatory subunit of protein phosphatase
2A. Development. Company of Biologists. https://doi.org/10.1242/dev.129.14.3493
chicago: Hannus, Michael, Fabian Feiguin, Carl-Philipp J Heisenberg, and Suzanne
Eaton. “Planar Cell Polarization Requires Widerborst, a B′ Regulatory Subunit
of Protein Phosphatase 2A.” Development. Company of Biologists, 2002. https://doi.org/10.1242/dev.129.14.3493.
ieee: M. Hannus, F. Feiguin, C.-P. J. Heisenberg, and S. Eaton, “Planar cell polarization
requires Widerborst, a B′ regulatory subunit of protein phosphatase 2A,” Development,
vol. 129, no. 14. Company of Biologists, pp. 3493–3503, 2002.
ista: Hannus M, Feiguin F, Heisenberg C-PJ, Eaton S. 2002. Planar cell polarization
requires Widerborst, a B′ regulatory subunit of protein phosphatase 2A. Development.
129(14), 3493–3503.
mla: Hannus, Michael, et al. “Planar Cell Polarization Requires Widerborst, a B′
Regulatory Subunit of Protein Phosphatase 2A.” Development, vol. 129, no.
14, Company of Biologists, 2002, pp. 3493–503, doi:10.1242/dev.129.14.3493.
short: M. Hannus, F. Feiguin, C.-P.J. Heisenberg, S. Eaton, Development 129 (2002)
3493–3503.
date_created: 2018-12-11T12:07:36Z
date_published: 2002-07-15T00:00:00Z
date_updated: 2023-06-06T14:07:49Z
day: '15'
doi: 10.1242/dev.129.14.3493
extern: '1'
external_id:
pmid:
- '12091318'
intvolume: ' 129'
issue: '14'
language:
- iso: eng
month: '07'
oa_version: None
page: 3493 - 3503
pmid: 1
publication: Development
publication_identifier:
issn:
- 0950-1991
publication_status: published
publisher: Company of Biologists
publist_id: '1909'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Planar cell polarization requires Widerborst, a B′ regulatory subunit of protein
phosphatase 2A
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 129
year: '2002'
...
---
_id: '4207'
abstract:
- lang: eng
text: Vertebrate homologues of the Strabismus/van Gogh (stbm/vang) gene have been
implicated in patterning and morphogenesis during gastrulation. Recent work shows
that stbm/vang is mutated in zebrafish trilobite mutants and that stbm/vang is
required for morphogenesis but not patterning during zebrafish gastrulation.
article_processing_charge: No
article_type: original
author:
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: 'Heisenberg C-PJ. Wnt signalling: Refocusing on Strabismus. Current Biology.
2002;12(19):R657-R659. doi:10.1016/S0960-9822(02)01160-0'
apa: 'Heisenberg, C.-P. J. (2002). Wnt signalling: Refocusing on Strabismus. Current
Biology. Cell Press. https://doi.org/10.1016/S0960-9822(02)01160-0'
chicago: 'Heisenberg, Carl-Philipp J. “Wnt Signalling: Refocusing on Strabismus.”
Current Biology. Cell Press, 2002. https://doi.org/10.1016/S0960-9822(02)01160-0.'
ieee: 'C.-P. J. Heisenberg, “Wnt signalling: Refocusing on Strabismus,” Current
Biology, vol. 12, no. 19. Cell Press, pp. R657–R659, 2002.'
ista: 'Heisenberg C-PJ. 2002. Wnt signalling: Refocusing on Strabismus. Current
Biology. 12(19), R657–R659.'
mla: 'Heisenberg, Carl-Philipp J. “Wnt Signalling: Refocusing on Strabismus.” Current
Biology, vol. 12, no. 19, Cell Press, 2002, pp. R657–59, doi:10.1016/S0960-9822(02)01160-0.'
short: C.-P.J. Heisenberg, Current Biology 12 (2002) R657–R659.
date_created: 2018-12-11T12:07:35Z
date_published: 2002-10-01T00:00:00Z
date_updated: 2023-06-06T15:09:53Z
day: '01'
doi: 10.1016/S0960-9822(02)01160-0
extern: '1'
external_id:
pmid:
- '12361585'
intvolume: ' 12'
issue: '19'
language:
- iso: eng
month: '10'
oa_version: None
page: R657 - R659
pmid: 1
publication: Current Biology
publication_identifier:
issn:
- 0960-9822
publication_status: published
publisher: Cell Press
publist_id: '1912'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Wnt signalling: Refocusing on Strabismus'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 12
year: '2002'
...
---
_id: '4194'
abstract:
- lang: eng
text: Cells at the anterior boundary of the neural plate (ANB) can induce telencephalic
gene expression when transplanted to more posterior regions. Here, we identify
a secreted Frizzled-related Wnt antagonist, Tic, that is expressed in ANB cells
and can cell nonautonomously promote telencephalic gene expression in a concentration-dependent
manner. Moreover, abrogation of Tlc function compromises telencephalic development.
We also identify Wnt8b as a locally acting modulator of regional fate in the anterior
neural plate and a likely target for antagonism by Tic. Finally, we show that
tlc expression is regulated by signals that establish early antero-posterior and
dorso-ventral ectodermal pattern. From these studies, we propose that local antagonism
of Wnt activity within the anterior ectoderm is required to establish the telencephalon.
acknowledgement: We thank many of our colleagues, especially Randy Moon, for providing reagents used
in this study. This study was supported by the Wellcome Trust, MRC, and BBSRC to
S.W.W. and C.H. S.W.W. is a Wellcome Trust Senior Research Fellow.
article_processing_charge: No
article_type: original
author:
- first_name: Corinne
full_name: Houart, Corinne
last_name: Houart
- first_name: Luca
full_name: Caneparo, Luca
last_name: Caneparo
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: K Anukampa
full_name: Barth, K Anukampa
last_name: Barth
- first_name: Masaya
full_name: Take Uchi, Masaya
last_name: Take Uchi
- first_name: Stephen
full_name: Wilson, Stephen
last_name: Wilson
citation:
ama: Houart C, Caneparo L, Heisenberg C-PJ, Barth KA, Take Uchi M, Wilson S. Establishment
of the telencephalon during gastrulation by local antagonism of Wnt signaling.
Neuron. 2002;35(2):255-265. doi:10.1016/S0896-6273(02)00751-1
apa: Houart, C., Caneparo, L., Heisenberg, C.-P. J., Barth, K. A., Take Uchi, M.,
& Wilson, S. (2002). Establishment of the telencephalon during gastrulation
by local antagonism of Wnt signaling. Neuron. Elsevier. https://doi.org/10.1016/S0896-6273(02)00751-1
chicago: Houart, Corinne, Luca Caneparo, Carl-Philipp J Heisenberg, K Anukampa Barth,
Masaya Take Uchi, and Stephen Wilson. “Establishment of the Telencephalon during
Gastrulation by Local Antagonism of Wnt Signaling.” Neuron. Elsevier, 2002.
https://doi.org/10.1016/S0896-6273(02)00751-1.
ieee: C. Houart, L. Caneparo, C.-P. J. Heisenberg, K. A. Barth, M. Take Uchi, and
S. Wilson, “Establishment of the telencephalon during gastrulation by local antagonism
of Wnt signaling,” Neuron, vol. 35, no. 2. Elsevier, pp. 255–265, 2002.
ista: Houart C, Caneparo L, Heisenberg C-PJ, Barth KA, Take Uchi M, Wilson S. 2002.
Establishment of the telencephalon during gastrulation by local antagonism of
Wnt signaling. Neuron. 35(2), 255–265.
mla: Houart, Corinne, et al. “Establishment of the Telencephalon during Gastrulation
by Local Antagonism of Wnt Signaling.” Neuron, vol. 35, no. 2, Elsevier,
2002, pp. 255–65, doi:10.1016/S0896-6273(02)00751-1.
short: C. Houart, L. Caneparo, C.-P.J. Heisenberg, K.A. Barth, M. Take Uchi, S.
Wilson, Neuron 35 (2002) 255–265.
date_created: 2018-12-11T12:07:30Z
date_published: 2002-07-18T00:00:00Z
date_updated: 2023-06-07T09:43:19Z
day: '18'
doi: 10.1016/S0896-6273(02)00751-1
extern: '1'
external_id:
pmid:
- '12160744'
intvolume: ' 35'
issue: '2'
language:
- iso: eng
month: '07'
oa_version: None
page: 255 - 265
pmid: 1
publication: Neuron
publication_identifier:
issn:
- 0896-6273
publication_status: published
publisher: Elsevier
publist_id: '1925'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Establishment of the telencephalon during gastrulation by local antagonism
of Wnt signaling
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 35
year: '2002'
...
---
_id: '4148'
abstract:
- lang: eng
text: Members of the Wnt family have been implicated in a variety of developmental
processes including axis formation, Patterning of the central nervous system and
tissue morphogenesis. Recent studies have shown that a Wnt signalling pathway
similar to that involved in the establishment of planar cell polarity in Drosophila
regulates convergent extension movements during zebrafish and Xenopus gastrulation.
This finding provides a good starting point to dissect the complex cell biology
and genetic regulation of vertebrate gastrulation movements.
acknowledgement: We would like to thank Steve Wilson for encouraging us to write this
article and for critical comments on this manuscript, and Lila Solnica-Krezel for
communicating results prior to publication. MT is supported by an MRC Career Development
Award, MLC by a Wellcome Trust Fellowship and CPH by an Emmy–Noether–Fellowship
from the DFG.
article_processing_charge: No
article_type: original
author:
- first_name: Masazumi
full_name: Tada, Masazumi
last_name: Tada
- first_name: Miguel
full_name: Concha, Miguel
last_name: Concha
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Tada M, Concha M, Heisenberg C-PJ. Non-canonical Wnt signalling and regulation
of gastrulation movements. Seminars in Cell & Developmental Biology.
2002;13(3):251-260. doi:10.1016/S1084-9521(02)00052-6
apa: Tada, M., Concha, M., & Heisenberg, C.-P. J. (2002). Non-canonical Wnt
signalling and regulation of gastrulation movements. Seminars in Cell &
Developmental Biology. Academic Press. https://doi.org/10.1016/S1084-9521(02)00052-6
chicago: Tada, Masazumi, Miguel Concha, and Carl-Philipp J Heisenberg. “Non-Canonical
Wnt Signalling and Regulation of Gastrulation Movements.” Seminars in Cell
& Developmental Biology. Academic Press, 2002. https://doi.org/10.1016/S1084-9521(02)00052-6.
ieee: M. Tada, M. Concha, and C.-P. J. Heisenberg, “Non-canonical Wnt signalling
and regulation of gastrulation movements,” Seminars in Cell & Developmental
Biology, vol. 13, no. 3. Academic Press, pp. 251–260, 2002.
ista: Tada M, Concha M, Heisenberg C-PJ. 2002. Non-canonical Wnt signalling and
regulation of gastrulation movements. Seminars in Cell & Developmental Biology.
13(3), 251–260.
mla: Tada, Masazumi, et al. “Non-Canonical Wnt Signalling and Regulation of Gastrulation
Movements.” Seminars in Cell & Developmental Biology, vol. 13, no.
3, Academic Press, 2002, pp. 251–60, doi:10.1016/S1084-9521(02)00052-6.
short: M. Tada, M. Concha, C.-P.J. Heisenberg, Seminars in Cell & Developmental
Biology 13 (2002) 251–260.
date_created: 2018-12-11T12:07:13Z
date_published: 2002-06-01T00:00:00Z
date_updated: 2023-06-07T09:50:14Z
day: '01'
doi: 10.1016/S1084-9521(02)00052-6
extern: '1'
external_id:
pmid:
- '12137734'
intvolume: ' 13'
issue: '3'
language:
- iso: eng
month: '06'
oa_version: None
page: 251 - 260
pmid: 1
publication: Seminars in Cell & Developmental Biology
publication_identifier:
issn:
- 1084-9521
publication_status: published
publisher: Academic Press
publist_id: '1973'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Non-canonical Wnt signalling and regulation of gastrulation movements
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 13
year: '2002'
...
---
_id: '4196'
abstract:
- lang: eng
text: During vertebrate gastrulation, large cellular rearrangements lead to the
formation of the three germ layers, ectoderm, mesoderm and endoderm. Zebrafish
offer many genetic and experimental advantages for studying vertebrate gastrulation
movements. For instance, several mutants, including silberblick, knypek and trilobite,
exhibit defects in morphogenesis during gastrulation. The identification of the
genes mutated in these lines together with the analysis of the mutant phenotypes
has provided new insights into the molecular and cellular mechanisms that underlie
vertebrate gastrulation movements.
acknowledgement: We would like to thank Miguel Concha, Will Norton, Tim Geach, Suzanne
Eaton, Kimbo Kotovic, Jenny Geiger and Steve Wilson for critical comments on this
manuscript, and Lila Solnica-Krezel for providing results prior to publication.
C.-P.H. is supported by an Emmy-Noether-Fellowship from the DFG and M.T. by an MRC
Career Development Award.
article_processing_charge: No
article_type: original
author:
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Masazumi
full_name: Tada, Masazumi
last_name: Tada
citation:
ama: 'Heisenberg C-PJ, Tada M. Zebrafish gastrulation movements: bridging cell and
developmental biology. Seminars in Cell & Developmental Biology. 2002;13(6):471-479.
doi:10.1016/S1084952102001003'
apa: 'Heisenberg, C.-P. J., & Tada, M. (2002). Zebrafish gastrulation movements:
bridging cell and developmental biology. Seminars in Cell & Developmental
Biology. Academic Press. https://doi.org/10.1016/S1084952102001003'
chicago: 'Heisenberg, Carl-Philipp J, and Masazumi Tada. “Zebrafish Gastrulation
Movements: Bridging Cell and Developmental Biology.” Seminars in Cell &
Developmental Biology. Academic Press, 2002. https://doi.org/10.1016/S1084952102001003.'
ieee: 'C.-P. J. Heisenberg and M. Tada, “Zebrafish gastrulation movements: bridging
cell and developmental biology,” Seminars in Cell & Developmental Biology,
vol. 13, no. 6. Academic Press, pp. 471–479, 2002.'
ista: 'Heisenberg C-PJ, Tada M. 2002. Zebrafish gastrulation movements: bridging
cell and developmental biology. Seminars in Cell & Developmental Biology.
13(6), 471–479.'
mla: 'Heisenberg, Carl-Philipp J., and Masazumi Tada. “Zebrafish Gastrulation Movements:
Bridging Cell and Developmental Biology.” Seminars in Cell & Developmental
Biology, vol. 13, no. 6, Academic Press, 2002, pp. 471–79, doi:10.1016/S1084952102001003.'
short: C.-P.J. Heisenberg, M. Tada, Seminars in Cell & Developmental Biology
13 (2002) 471–479.
date_created: 2018-12-11T12:07:31Z
date_published: 2002-12-01T00:00:00Z
date_updated: 2023-06-07T09:28:48Z
day: '01'
doi: 10.1016/S1084952102001003
extern: '1'
external_id:
pmid:
- '12468250'
intvolume: ' 13'
issue: '6'
language:
- iso: eng
month: '12'
oa_version: None
page: 471 - 479
pmid: 1
publication: Seminars in Cell & Developmental Biology
publication_identifier:
issn:
- 1084-9521
publication_status: published
publisher: Academic Press
publist_id: '1920'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Zebrafish gastrulation movements: bridging cell and developmental biology'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 13
year: '2002'
...
---
_id: '4199'
abstract:
- lang: eng
text: Recent studies on vertebrate homologues of the van gogh/strabismus (vang/stbm)
gene, a key player in planar cell polarity signalling in Drosophila, show that
vang/stbm is involved in patterning and morphogenesis during vertebrate gastrulation
where it modulates two distinct Wnt signals.
article_processing_charge: No
article_type: original
author:
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Masazumi
full_name: Tada, Masazumi
last_name: Tada
citation:
ama: 'Heisenberg C-PJ, Tada M. Wnt signalling: A moving picture emerges from van
gogh. Current Biology. 2002;12(4):R126-R128. doi:10.1016/S0960-9822(02)00704-2'
apa: 'Heisenberg, C.-P. J., & Tada, M. (2002). Wnt signalling: A moving picture
emerges from van gogh. Current Biology. Cell Press. https://doi.org/10.1016/S0960-9822(02)00704-2'
chicago: 'Heisenberg, Carl-Philipp J, and Masazumi Tada. “Wnt Signalling: A Moving
Picture Emerges from van Gogh.” Current Biology. Cell Press, 2002. https://doi.org/10.1016/S0960-9822(02)00704-2.'
ieee: 'C.-P. J. Heisenberg and M. Tada, “Wnt signalling: A moving picture emerges
from van gogh,” Current Biology, vol. 12, no. 4. Cell Press, pp. R126–R128,
2002.'
ista: 'Heisenberg C-PJ, Tada M. 2002. Wnt signalling: A moving picture emerges from
van gogh. Current Biology. 12(4), R126–R128.'
mla: 'Heisenberg, Carl-Philipp J., and Masazumi Tada. “Wnt Signalling: A Moving
Picture Emerges from van Gogh.” Current Biology, vol. 12, no. 4, Cell Press,
2002, pp. R126–28, doi:10.1016/S0960-9822(02)00704-2.'
short: C.-P.J. Heisenberg, M. Tada, Current Biology 12 (2002) R126–R128.
date_created: 2018-12-11T12:07:32Z
date_published: 2002-02-19T00:00:00Z
date_updated: 2023-06-07T08:54:35Z
day: '19'
doi: 10.1016/S0960-9822(02)00704-2
extern: '1'
external_id:
pmid:
- '11864583'
intvolume: ' 12'
issue: '4'
language:
- iso: eng
month: '02'
oa_version: None
page: R126 - R128
pmid: 1
publication: Current Biology
publication_identifier:
issn:
- 0960-9822
publication_status: published
publisher: Cell Press
publist_id: '1919'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Wnt signalling: A moving picture emerges from van gogh'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 12
year: '2002'
...
---
_id: '4139'
abstract:
- lang: eng
text: Pilot studies in England by Stopka and Macdonald revealed that allogrooming
in the Old World wood mouse, Apodemus sylvaticus, is a commodity that males can
trade for reproductive benefits with females. This study, which used a combination
of field study and observations in experimental enclosures, revealed that specific
experimental conditions such as group-size and sex-ratio manipulations have a
significant effect on the pattern of allogrooming exchanged between individuals.
Furthermore, females from the Czech population were more likely to associate with
each other as revealed by the clustering of activity centers of females (i.e.,
as opposed to almost exclusive ranges in English populations), and also by the
higher intensity of allogrooming exchanged between females (i.e., virtually lacking
in the previous experiment with English mice). Therefore, geographic variation
and specific social conditions seem to be important driving factors for allogrooming
behavior. Together with changes in overall grooming patterns, allogrooming between
males and females remained invariably asymmetrical over all four experimental
groups (i.e., two conditions for each sex) in that males provided more allogrooming
to females than they received from them.
article_processing_charge: No
article_type: original
author:
- first_name: Jitka
full_name: Polechova, Jitka
id: 3BBFB084-F248-11E8-B48F-1D18A9856A87
last_name: Polechova
orcid: 0000-0003-0951-3112
- first_name: P.
full_name: Stopka, P.
last_name: Stopka
citation:
ama: Polechova J, Stopka P. Geometry of social relationships in the Old World wood
mouse, Apodemus sylvaticus. Canadian Journal of Zoology. 2002;80(8):1383-1388.
doi:10.1139/z02-128
apa: Polechova, J., & Stopka, P. (2002). Geometry of social relationships in
the Old World wood mouse, Apodemus sylvaticus. Canadian Journal of Zoology.
NRC Research Press. https://doi.org/10.1139/z02-128
chicago: Polechova, Jitka, and P. Stopka. “Geometry of Social Relationships in the
Old World Wood Mouse, Apodemus Sylvaticus.” Canadian Journal of Zoology.
NRC Research Press, 2002. https://doi.org/10.1139/z02-128.
ieee: J. Polechova and P. Stopka, “Geometry of social relationships in the Old World
wood mouse, Apodemus sylvaticus,” Canadian Journal of Zoology, vol. 80,
no. 8. NRC Research Press, pp. 1383–1388, 2002.
ista: Polechova J, Stopka P. 2002. Geometry of social relationships in the Old World
wood mouse, Apodemus sylvaticus. Canadian Journal of Zoology. 80(8), 1383–1388.
mla: Polechova, Jitka, and P. Stopka. “Geometry of Social Relationships in the Old
World Wood Mouse, Apodemus Sylvaticus.” Canadian Journal of Zoology, vol.
80, no. 8, NRC Research Press, 2002, pp. 1383–88, doi:10.1139/z02-128.
short: J. Polechova, P. Stopka, Canadian Journal of Zoology 80 (2002) 1383–1388.
date_created: 2018-12-11T12:07:10Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-06-07T12:53:35Z
day: '01'
doi: 10.1139/z02-128
extern: '1'
intvolume: ' 80'
issue: '8'
language:
- iso: eng
month: '01'
oa_version: None
page: 1383 - 1388
publication: Canadian Journal of Zoology
publication_identifier:
issn:
- 0008-4301
publication_status: published
publisher: NRC Research Press
publist_id: '1981'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Geometry of social relationships in the Old World wood mouse, Apodemus sylvaticus
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 80
year: '2002'
...
---
_id: '4003'
abstract:
- lang: eng
text: The writhing number measures the global geometry of a closed space curve or
knot. We show that this measure is related to the average winding number of its
Gauss map. Using this relationship, we give an algorithm for computing the writhing
number for a polygonal knot with n edges in time roughly proportional to n(1.6).
We also implement a different, simple algorithm and provide experimental evidence
for its practical efficiency.
acknowledgement: NSF under grants CCR-00-86013 and EIA-9972879, NSF under grant CCR-97-12088.
article_processing_charge: No
author:
- first_name: Pankaj
full_name: Agarwal, Pankaj
last_name: Agarwal
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Yusu
full_name: Wang, Yusu
last_name: Wang
citation:
ama: 'Agarwal P, Edelsbrunner H, Wang Y. Computing the writhing number of a polygonal
knot. In: Proceedings of the 13th Annual ACM-SIAM Symposium on Discrete Algorithms.
SIAM; 2002:791-799.'
apa: 'Agarwal, P., Edelsbrunner, H., & Wang, Y. (2002). Computing the writhing
number of a polygonal knot. In Proceedings of the 13th annual ACM-SIAM symposium
on Discrete algorithms (pp. 791–799). San Francisco, CA, USA: SIAM.'
chicago: Agarwal, Pankaj, Herbert Edelsbrunner, and Yusu Wang. “Computing the Writhing
Number of a Polygonal Knot.” In Proceedings of the 13th Annual ACM-SIAM Symposium
on Discrete Algorithms, 791–99. SIAM, 2002.
ieee: P. Agarwal, H. Edelsbrunner, and Y. Wang, “Computing the writhing number of
a polygonal knot,” in Proceedings of the 13th annual ACM-SIAM symposium on
Discrete algorithms, San Francisco, CA, USA, 2002, pp. 791–799.
ista: 'Agarwal P, Edelsbrunner H, Wang Y. 2002. Computing the writhing number of
a polygonal knot. Proceedings of the 13th annual ACM-SIAM symposium on Discrete
algorithms. SODA: Symposium on Discrete Algorithms, 791–799.'
mla: Agarwal, Pankaj, et al. “Computing the Writhing Number of a Polygonal Knot.”
Proceedings of the 13th Annual ACM-SIAM Symposium on Discrete Algorithms,
SIAM, 2002, pp. 791–99.
short: P. Agarwal, H. Edelsbrunner, Y. Wang, in:, Proceedings of the 13th Annual
ACM-SIAM Symposium on Discrete Algorithms, SIAM, 2002, pp. 791–799.
conference:
end_date: 2002-01-08
location: San Francisco, CA, USA
name: 'SODA: Symposium on Discrete Algorithms'
start_date: 2002-01-06
date_created: 2018-12-11T12:06:23Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-06-07T13:50:04Z
day: '01'
extern: '1'
language:
- iso: eng
main_file_link:
- url: https://dl.acm.org/doi/10.5555/545381.545485
month: '01'
oa_version: None
page: 791 - 799
publication: Proceedings of the 13th annual ACM-SIAM symposium on Discrete algorithms
publication_identifier:
isbn:
- '9780898715132'
publication_status: published
publisher: SIAM
publist_id: '2125'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Computing the writhing number of a polygonal knot
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '2002'
...
---
_id: '3995'
abstract:
- lang: eng
text: This article is a survey of research areas in which motion plays a pivotal
role. The aim of the article is to review current approaches to modeling motion
together with related data structures and algorithms, and to summarize the challenges
that lie ahead in producing a more unified theory of motion representation that
would be useful across several disciplines.
acknowledgement: "This article is based on the report of the Workshop on Algorithmic
Issues in Modeling Motion, sponsored\r\nby an NSF grant CCR-00-83-033 and an Army
Research Office grant DAAD 19-00-1-0478, held on August 6\r\nand 7, 2000 at Duke
University, Durham, NC."
article_processing_charge: No
article_type: original
author:
- first_name: Pankaj
full_name: Agarwal, Pankaj
last_name: Agarwal
- first_name: Leonidas
full_name: Guibas, Leonidas
last_name: Guibas
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Jeff
full_name: Erickson, Jeff
last_name: Erickson
- first_name: Michael
full_name: Isard, Michael
last_name: Isard
- first_name: Sariel
full_name: Har Peled, Sariel
last_name: Har Peled
- first_name: John
full_name: Hershberger, John
last_name: Hershberger
- first_name: Christian
full_name: Jensen, Christian
last_name: Jensen
- first_name: Lydia
full_name: Kavraki, Lydia
last_name: Kavraki
- first_name: Patrice
full_name: Koehl, Patrice
last_name: Koehl
- first_name: Ming
full_name: Lin, Ming
last_name: Lin
- first_name: Dinesh
full_name: Manocha, Dinesh
last_name: Manocha
- first_name: Dimitris
full_name: Metaxas, Dimitris
last_name: Metaxas
- first_name: Brian
full_name: Mirtich, Brian
last_name: Mirtich
- first_name: David
full_name: Mount, David
last_name: Mount
- first_name: Sankara
full_name: Muthukrishnan, Sankara
last_name: Muthukrishnan
- first_name: Dinesh
full_name: Pai, Dinesh
last_name: Pai
- first_name: Elisha
full_name: Sacks, Elisha
last_name: Sacks
- first_name: Jack
full_name: Snoeyink, Jack
last_name: Snoeyink
- first_name: Subhash
full_name: Suri, Subhash
last_name: Suri
- first_name: Ouri
full_name: Wolefson, Ouri
last_name: Wolefson
citation:
ama: Agarwal P, Guibas L, Edelsbrunner H, et al. Algorithmic issues in modeling
motion. ACM Computing Surveys. 2002;34(4):550-572. doi:10.1145/592642.592647
apa: Agarwal, P., Guibas, L., Edelsbrunner, H., Erickson, J., Isard, M., Har Peled,
S., … Wolefson, O. (2002). Algorithmic issues in modeling motion. ACM Computing
Surveys. ACM. https://doi.org/10.1145/592642.592647
chicago: Agarwal, Pankaj, Leonidas Guibas, Herbert Edelsbrunner, Jeff Erickson,
Michael Isard, Sariel Har Peled, John Hershberger, et al. “Algorithmic Issues
in Modeling Motion.” ACM Computing Surveys. ACM, 2002. https://doi.org/10.1145/592642.592647.
ieee: P. Agarwal et al., “Algorithmic issues in modeling motion,” ACM
Computing Surveys, vol. 34, no. 4. ACM, pp. 550–572, 2002.
ista: Agarwal P, Guibas L, Edelsbrunner H, Erickson J, Isard M, Har Peled S, Hershberger
J, Jensen C, Kavraki L, Koehl P, Lin M, Manocha D, Metaxas D, Mirtich B, Mount
D, Muthukrishnan S, Pai D, Sacks E, Snoeyink J, Suri S, Wolefson O. 2002. Algorithmic
issues in modeling motion. ACM Computing Surveys. 34(4), 550–572.
mla: Agarwal, Pankaj, et al. “Algorithmic Issues in Modeling Motion.” ACM Computing
Surveys, vol. 34, no. 4, ACM, 2002, pp. 550–72, doi:10.1145/592642.592647.
short: P. Agarwal, L. Guibas, H. Edelsbrunner, J. Erickson, M. Isard, S. Har Peled,
J. Hershberger, C. Jensen, L. Kavraki, P. Koehl, M. Lin, D. Manocha, D. Metaxas,
B. Mirtich, D. Mount, S. Muthukrishnan, D. Pai, E. Sacks, J. Snoeyink, S. Suri,
O. Wolefson, ACM Computing Surveys 34 (2002) 550–572.
date_created: 2018-12-11T12:06:20Z
date_published: 2002-12-01T00:00:00Z
date_updated: 2023-06-13T11:34:25Z
day: '01'
doi: 10.1145/592642.592647
extern: '1'
intvolume: ' 34'
issue: '4'
language:
- iso: eng
month: '12'
oa_version: None
page: 550 - 572
publication: ACM Computing Surveys
publication_identifier:
issn:
- 0360-0300
publication_status: published
publisher: ACM
publist_id: '2129'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Algorithmic issues in modeling motion
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 34
year: '2002'
...
---
_id: '4000'
abstract:
- lang: eng
text: We present fast implementations of a hybrid algorithm for reporting box and
cube intersections. Our algorithm initially takes a divide-and-conquer approach
and switches to simpler algorithms for low numbers of boxes. We use our implementations
as engines to solve problems about geometric primitives. We look at two such problems
in the category of quality analysis of surface triangulations.
acknowledgement: Center for Simulation of Advanced Rockets funded by the U.S. Department
of Energy under Subcontract B341494, NSF under grant CCR-96-19542 and ARO under
grant DAAG55-98-1-0177.
article_processing_charge: No
article_type: original
author:
- first_name: Afra
full_name: Zomorodian, Afra
last_name: Zomorodian
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
citation:
ama: Zomorodian A, Edelsbrunner H. Fast software for box intersections. International
Journal of Computational Geometry and Applications. 2002;12(1-2):143-172.
doi:10.1142/S0218195902000785
apa: Zomorodian, A., & Edelsbrunner, H. (2002). Fast software for box intersections.
International Journal of Computational Geometry and Applications. World
Scientific Publishing. https://doi.org/10.1142/S0218195902000785
chicago: Zomorodian, Afra, and Herbert Edelsbrunner. “Fast Software for Box Intersections.”
International Journal of Computational Geometry and Applications. World
Scientific Publishing, 2002. https://doi.org/10.1142/S0218195902000785.
ieee: A. Zomorodian and H. Edelsbrunner, “Fast software for box intersections,”
International Journal of Computational Geometry and Applications, vol.
12, no. 1–2. World Scientific Publishing, pp. 143–172, 2002.
ista: Zomorodian A, Edelsbrunner H. 2002. Fast software for box intersections. International
Journal of Computational Geometry and Applications. 12(1–2), 143–172.
mla: Zomorodian, Afra, and Herbert Edelsbrunner. “Fast Software for Box Intersections.”
International Journal of Computational Geometry and Applications, vol.
12, no. 1–2, World Scientific Publishing, 2002, pp. 143–72, doi:10.1142/S0218195902000785.
short: A. Zomorodian, H. Edelsbrunner, International Journal of Computational Geometry
and Applications 12 (2002) 143–172.
date_created: 2018-12-11T12:06:22Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-06-13T11:20:09Z
day: '01'
doi: 10.1142/S0218195902000785
extern: '1'
intvolume: ' 12'
issue: 1-2
language:
- iso: eng
month: '01'
oa_version: None
page: 143 - 172
publication: International Journal of Computational Geometry and Applications
publication_identifier:
issn:
- 0218-1959
publication_status: published
publisher: World Scientific Publishing
publist_id: '2128'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Fast software for box intersections
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 12
year: '2002'
...
---
_id: '3998'
abstract:
- lang: eng
text: We present results on a two-step improvement of mesh quality in three-dimensional
Delaunay triangulations. The first step refines the triangulation by inserting
sinks and eliminates tetrahedra with large circumradius over shortest edge length
ratio. The second step assigns weights to the vertices to eliminate slivers. Our
experimental findings provide evidence for the practical effectiveness of sliver
exudation.
acknowledgement: NSF under grants CCR-97-12088 and DMS 98-73945, NSF under grands
EIA-9972879 and CCR-00-86013 and by ARO under grant DAAG55-98-1- 0177.
article_processing_charge: No
article_type: original
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Damrong
full_name: Guoy, Damrong
last_name: Guoy
citation:
ama: Edelsbrunner H, Guoy D. An experimental study of sliver exudation. Engineering
with Computers. 2002;18(3):229-240. doi:10.1007/s003660200020
apa: Edelsbrunner, H., & Guoy, D. (2002). An experimental study of sliver exudation.
Engineering with Computers. Springer. https://doi.org/10.1007/s003660200020
chicago: Edelsbrunner, Herbert, and Damrong Guoy. “An Experimental Study of Sliver
Exudation.” Engineering with Computers. Springer, 2002. https://doi.org/10.1007/s003660200020.
ieee: H. Edelsbrunner and D. Guoy, “An experimental study of sliver exudation,”
Engineering with Computers, vol. 18, no. 3. Springer, pp. 229–240, 2002.
ista: Edelsbrunner H, Guoy D. 2002. An experimental study of sliver exudation. Engineering
with Computers. 18(3), 229–240.
mla: Edelsbrunner, Herbert, and Damrong Guoy. “An Experimental Study of Sliver Exudation.”
Engineering with Computers, vol. 18, no. 3, Springer, 2002, pp. 229–40,
doi:10.1007/s003660200020.
short: H. Edelsbrunner, D. Guoy, Engineering with Computers 18 (2002) 229–240.
date_created: 2018-12-11T12:06:21Z
date_published: 2002-10-01T00:00:00Z
date_updated: 2023-06-13T11:14:44Z
day: '01'
doi: 10.1007/s003660200020
extern: '1'
intvolume: ' 18'
issue: '3'
language:
- iso: eng
month: '10'
oa_version: None
page: 229 - 240
publication: Engineering with Computers
publication_identifier:
issn:
- 0177-0667
publication_status: published
publisher: Springer
publist_id: '2126'
quality_controlled: '1'
scopus_import: '1'
status: public
title: An experimental study of sliver exudation
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 18
year: '2002'
...
---
_id: '3802'
abstract:
- lang: eng
text: The presynaptic Ca2+ signal is a key determinant of transmitter release at
chemical synapses. In cortical synaptic terminals, however, little is known about
the kinetic properties of the presynaptic Ca2+ channels. To investigate the timing
and magnitude of the presynaptic Ca2+ inflow, we performed whole-cell patch-clamp
recordings from mossy fiber boutons (MFBs) in rat hippocampus. MFBs showed large
high-voltage-activated Ca(2+) currents, with a maximal amplitude of approximately
100 pA at a membrane potential of 0 mV. Both activation and deactivation were
fast, with time constants in the submillisecond range at a temperature of approximately
23 degrees C. An MFB action potential (AP) applied as a voltage-clamp command
evoked a transient Ca2+ current with an average amplitude of approximately 170
pA and a half-duration of 580 microsec. A prepulse to +40 mV had only minimal
effects on the AP-evoked Ca2+ current, indicating that presynaptic APs open the
voltage-gated Ca2+ channels very effectively. On the basis of the experimental
data, we developed a kinetic model with four closed states and one open state,
linked by voltage-dependent rate constants. Simulations of the Ca2+ current could
reproduce the experimental data, including the large amplitude and rapid time
course of the current evoked by MFB APs. Furthermore, the simulations indicate
that the shape of the presynaptic AP and the gating kinetics of the Ca2+ channels
are tuned to produce a maximal Ca2+ influx during a minimal period of time. The
precise timing and high efficacy of Ca2+ channel activation at this cortical glutamatergic
synapse may be important for synchronous transmitter release and temporal information
processing.
acknowledgement: J.B. was supported by grants from the Deutsche Forschungsgemeinschaft
(Bi 642/1-2 and SFB 505/C9). We thank Dr. U. Kraushaar, Dr. S. Hefft, and C. Schmidt-Hieber
for critically reading this manuscript, F. Heyde for secretarial help, and A. Blomenkamp
and K. Winterhalter for technical assistance.
article_processing_charge: No
article_type: original
author:
- first_name: Josef
full_name: Bischofberger, Josef
last_name: Bischofberger
- first_name: Jörg
full_name: Geiger, Jörg
last_name: Geiger
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Bischofberger J, Geiger J, Jonas PM. Timing and efficacy of Ca(2+) channel
activation in hippocampal mossy fiber boutons. Journal of Neuroscience.
2002;22(24):10593-10602. doi:10.1523/JNEUROSCI.22-24-10593.2002
apa: Bischofberger, J., Geiger, J., & Jonas, P. M. (2002). Timing and efficacy
of Ca(2+) channel activation in hippocampal mossy fiber boutons. Journal of
Neuroscience. Society for Neuroscience. https://doi.org/10.1523/JNEUROSCI.22-24-10593.2002
chicago: Bischofberger, Josef, Jörg Geiger, and Peter M Jonas. “Timing and Efficacy
of Ca(2+) Channel Activation in Hippocampal Mossy Fiber Boutons.” Journal of
Neuroscience. Society for Neuroscience, 2002. https://doi.org/10.1523/JNEUROSCI.22-24-10593.2002.
ieee: J. Bischofberger, J. Geiger, and P. M. Jonas, “Timing and efficacy of Ca(2+)
channel activation in hippocampal mossy fiber boutons,” Journal of Neuroscience,
vol. 22, no. 24. Society for Neuroscience, pp. 10593–10602, 2002.
ista: Bischofberger J, Geiger J, Jonas PM. 2002. Timing and efficacy of Ca(2+) channel
activation in hippocampal mossy fiber boutons. Journal of Neuroscience. 22(24),
10593–10602.
mla: Bischofberger, Josef, et al. “Timing and Efficacy of Ca(2+) Channel Activation
in Hippocampal Mossy Fiber Boutons.” Journal of Neuroscience, vol. 22,
no. 24, Society for Neuroscience, 2002, pp. 10593–602, doi:10.1523/JNEUROSCI.22-24-10593.2002.
short: J. Bischofberger, J. Geiger, P.M. Jonas, Journal of Neuroscience 22 (2002)
10593–10602.
date_created: 2018-12-11T12:05:15Z
date_published: 2002-12-01T00:00:00Z
date_updated: 2023-06-13T13:19:45Z
day: '01'
doi: 10.1523/JNEUROSCI.22-24-10593.2002
extern: '1'
external_id:
pmid:
- '12486151'
intvolume: ' 22'
issue: '24'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6758411/
month: '12'
oa: 1
oa_version: Published Version
page: 10593 - 10602
pmid: 1
publication: Journal of Neuroscience
publication_identifier:
issn:
- 0270-6474
publication_status: published
publisher: Society for Neuroscience
publist_id: '2407'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Timing and efficacy of Ca(2+) channel activation in hippocampal mossy fiber
boutons
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 22
year: '2002'
...
---
_id: '3919'
abstract:
- lang: eng
text: Hamilton's concept of local mate competition (LMC) is the standard model to
explain female-biased sex ratios in solitary Hymenoptera. In social Hymenoptera,
however, LMC has remained controversial, mainly because manipulation of sex allocation
by workers in response to relatedness asymmetries is an additional powerful mechanism
of female bias. Furthermore, the predominant mating systems in the social insects
are thought to make LMC unlikely. Nevertheless, several species exist in which
dispersal of males is limited and mating occurs in the nest. Some of these species,
such as the ant Cardiocondyla obscurior, have evolved dimorphic males, with one
morph being specialized for dispersal and the other for fighting with nest-mate
males over access to females. Such life history, combining sociality and alternative
reproductive tactics in males, provides a unique opportunity to test the power
of LMC as a selective force leading to female-biased sex ratios in social Hymenoptera.
We show that, in concordance with LMC predictions, an experimental increase in
queen number leads to a shift in sex allocation in favour of non-dispersing males,
but does not influence the proportion of disperser males. Furthermore, we can
assign this change in sex allocation at the colony level to the queens and rule
out worker manipulation.
acknowledgement: 'We thank A. F. G. Bourke, J. J. Boomsma, S. Foitzik, M. Sixt,C.
Anderson and C. Schubart for improving the manuscript, and E. Sixt for ant illustrations (figure 2). This study was
funded by the DFG (Deutsche Forschungsgemeinschaft: He1623/7-2).'
article_processing_charge: No
article_type: original
author:
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
- first_name: Jürgen
full_name: Heinze, Jürgen
last_name: Heinze
citation:
ama: 'Cremer S, Heinze J. Adaptive production of fighter males: queens of the ant
Cardiocondyla adjust the sex ratio under local mate competition. Proceedings
of the Royal Society of London Series B Biological Sciences. 2002;269(1489):417-422.
doi:10.1098/rspb.2001.1892'
apa: 'Cremer, S., & Heinze, J. (2002). Adaptive production of fighter males:
queens of the ant Cardiocondyla adjust the sex ratio under local mate competition.
Proceedings of the Royal Society of London Series B Biological Sciences.
Royal Society, The. https://doi.org/10.1098/rspb.2001.1892'
chicago: 'Cremer, Sylvia, and Jürgen Heinze. “Adaptive Production of Fighter Males:
Queens of the Ant Cardiocondyla Adjust the Sex Ratio under Local Mate Competition.”
Proceedings of the Royal Society of London Series B Biological Sciences.
Royal Society, The, 2002. https://doi.org/10.1098/rspb.2001.1892.'
ieee: 'S. Cremer and J. Heinze, “Adaptive production of fighter males: queens of
the ant Cardiocondyla adjust the sex ratio under local mate competition,” Proceedings
of the Royal Society of London Series B Biological Sciences, vol. 269, no.
1489. Royal Society, The, pp. 417–422, 2002.'
ista: 'Cremer S, Heinze J. 2002. Adaptive production of fighter males: queens of
the ant Cardiocondyla adjust the sex ratio under local mate competition. Proceedings
of the Royal Society of London Series B Biological Sciences. 269(1489), 417–422.'
mla: 'Cremer, Sylvia, and Jürgen Heinze. “Adaptive Production of Fighter Males:
Queens of the Ant Cardiocondyla Adjust the Sex Ratio under Local Mate Competition.”
Proceedings of the Royal Society of London Series B Biological Sciences,
vol. 269, no. 1489, Royal Society, The, 2002, pp. 417–22, doi:10.1098/rspb.2001.1892.'
short: S. Cremer, J. Heinze, Proceedings of the Royal Society of London Series B
Biological Sciences 269 (2002) 417–422.
date_created: 2018-12-11T12:05:53Z
date_published: 2002-02-22T00:00:00Z
date_updated: 2023-06-13T11:52:17Z
day: '22'
doi: 10.1098/rspb.2001.1892
extern: '1'
external_id:
pmid:
- '11886631'
intvolume: ' 269'
issue: '1489'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1690910/
month: '02'
oa: 1
oa_version: None
page: 417 - 422
pmid: 1
publication: Proceedings of the Royal Society of London Series B Biological Sciences
publication_identifier:
issn:
- 0962-8452
publication_status: published
publisher: Royal Society, The
publist_id: '2231'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Adaptive production of fighter males: queens of the ant Cardiocondyla adjust
the sex ratio under local mate competition'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 269
year: '2002'
...
---
_id: '3924'
abstract:
- lang: eng
text: 'Males of the ant Cardiocondyla show a dispersal dimorphism of a winged and
wingless morph. The loss of flight has lead to morphological reductions in the
wingless (ergatoid) males and also affected body size, eye size and pigmentation.
As ergatoid males mate exclusively inside the maternal nest, they underlie increased
male-male competition and therefore have also evolved additional changes in behaviour
and physiology: in contrast to winged males, ergatoid males are highly aggressive
towards each other and their spermatogenesis is prolonged compared to all other
hymenopteran males. In addition to these two male morphs, we found males with
an intermediate appearance. These "intermorphic" males provide a transitional
stage between normal males in most investigated morphological and physiological
parameters. As they are produced extremely rarely and only in colonies that switch
between pure ergatoid to mixed male production, we argue that they likely represent
a developmental mistake. Parallels between the determination of male morphs and
female castes (queen-worker dimorphism and worker polymorphism) might help to
understand how the large potential of phenotypic plasticity in both sexes of social
insects is realised during development.'
acknowledgement: We would like to thank S. Karpeles for histological analysis of the
winged males and S. Buchhauser for help with the photographs. This study was funded
by the DFG (grant He1623/12–1).
article_processing_charge: No
article_type: original
author:
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
- first_name: Birgit
full_name: Lautenschläger, Birgit
last_name: Lautenschläger
- first_name: Jürgen
full_name: Heinze, Jürgen
last_name: Heinze
citation:
ama: Cremer S, Lautenschläger B, Heinze J. A transitional stage between the ergatoid
and winged male morph in the ant Cardiocondyla obscurior. Insectes Sociaux.
2002;49(3):221-228. doi:10.1007/s00040-002-8305-z
apa: Cremer, S., Lautenschläger, B., & Heinze, J. (2002). A transitional stage
between the ergatoid and winged male morph in the ant Cardiocondyla obscurior.
Insectes Sociaux. Springer. https://doi.org/10.1007/s00040-002-8305-z
chicago: Cremer, Sylvia, Birgit Lautenschläger, and Jürgen Heinze. “A Transitional
Stage between the Ergatoid and Winged Male Morph in the Ant Cardiocondyla Obscurior.”
Insectes Sociaux. Springer, 2002. https://doi.org/10.1007/s00040-002-8305-z.
ieee: S. Cremer, B. Lautenschläger, and J. Heinze, “A transitional stage between
the ergatoid and winged male morph in the ant Cardiocondyla obscurior,” Insectes
Sociaux, vol. 49, no. 3. Springer, pp. 221–228, 2002.
ista: Cremer S, Lautenschläger B, Heinze J. 2002. A transitional stage between the
ergatoid and winged male morph in the ant Cardiocondyla obscurior. Insectes Sociaux.
49(3), 221–228.
mla: Cremer, Sylvia, et al. “A Transitional Stage between the Ergatoid and Winged
Male Morph in the Ant Cardiocondyla Obscurior.” Insectes Sociaux, vol.
49, no. 3, Springer, 2002, pp. 221–28, doi:10.1007/s00040-002-8305-z.
short: S. Cremer, B. Lautenschläger, J. Heinze, Insectes Sociaux 49 (2002) 221–228.
date_created: 2018-12-11T12:05:55Z
date_published: 2002-04-05T00:00:00Z
date_updated: 2023-06-13T11:44:08Z
day: '05'
doi: 10.1007/s00040-002-8305-z
extern: '1'
intvolume: ' 49'
issue: '3'
language:
- iso: eng
month: '04'
oa_version: None
page: 221 - 228
publication: Insectes Sociaux
publication_identifier:
issn:
- 0020-1812
publication_status: published
publisher: Springer
publist_id: '2229'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A transitional stage between the ergatoid and winged male morph in the ant
Cardiocondyla obscurior
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 49
year: '2002'
...
---
_id: '3925'
abstract:
- lang: eng
text: Males of the tropical ant Cardiocondyla obscurior are either wingless and
aggressive or winged and docile, and both compete for access to virgin queens
in the nest1, 2. Although the fighter males (ergatoids) attack and kill other
ergatoids, they tolerate and even attempt to mate with their winged rivals. Here
we show that the winged males avoid the aggression of wingless males by mimicking
the chemical bouquet of virgin queens, but that their mating success is not reduced
as a result. This example of female mimicry by vigorous males is surprising, as
in other species it is typically used as a protective strategy by weaker males,
and may explain the coexistence and equal mating success of two male morphs.
article_processing_charge: No
article_type: original
author:
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
- first_name: Matthew
full_name: Sledge, Matthew
last_name: Sledge
- first_name: Jürgen
full_name: Heinze, Jürgen
last_name: Heinze
citation:
ama: 'Cremer S, Sledge M, Heinze J. Chemical mimicry: Male ants disguised by the
queen’s bouquet. Nature. 2002;419:897-897. doi:10.1038/419897a'
apa: 'Cremer, S., Sledge, M., & Heinze, J. (2002). Chemical mimicry: Male ants
disguised by the queen’s bouquet. Nature. Nature Publishing Group. https://doi.org/10.1038/419897a'
chicago: 'Cremer, Sylvia, Matthew Sledge, and Jürgen Heinze. “Chemical Mimicry:
Male Ants Disguised by the Queen’s Bouquet.” Nature. Nature Publishing
Group, 2002. https://doi.org/10.1038/419897a.'
ieee: 'S. Cremer, M. Sledge, and J. Heinze, “Chemical mimicry: Male ants disguised
by the queen’s bouquet,” Nature, vol. 419. Nature Publishing Group, pp.
897–897, 2002.'
ista: 'Cremer S, Sledge M, Heinze J. 2002. Chemical mimicry: Male ants disguised
by the queen’s bouquet. Nature. 419, 897–897.'
mla: 'Cremer, Sylvia, et al. “Chemical Mimicry: Male Ants Disguised by the Queen’s
Bouquet.” Nature, vol. 419, Nature Publishing Group, 2002, pp. 897–897,
doi:10.1038/419897a.'
short: S. Cremer, M. Sledge, J. Heinze, Nature 419 (2002) 897–897.
date_created: 2018-12-11T12:05:55Z
date_published: 2002-10-31T00:00:00Z
date_updated: 2023-06-13T11:47:19Z
day: '31'
doi: 10.1038/419897a
extern: '1'
external_id:
pmid:
- '12410300'
intvolume: ' 419'
language:
- iso: eng
month: '10'
oa_version: None
page: 897 - 897
pmid: 1
publication: Nature
publication_identifier:
issn:
- 0028-0836
publication_status: published
publisher: Nature Publishing Group
publist_id: '2230'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Chemical mimicry: Male ants disguised by the queen''s bouquet'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 419
year: '2002'
...
---
_id: '3996'
abstract:
- lang: eng
text: We formalize a notion of topological simplification within the framework of
a filtration, which is the history of a growing complex. We classify a topological
change that happens during growth as either a feature or noise depending on its
lifetime or persistence within the filtration. We give fast algorithms for computing
persistence and experimental evidence for their speed and utility.
acknowledgement: "We thank Jeff Erickson and John Harer for helpful discussions during
early stages of this\r\npaper. We also thank Daniel Huson for the zeolite dataset
Z, Thomas LaBean for the DNA\r\ndataset D, and the Stanford Graphics Lab for the
Buddha dataset S. To generate the bone\r\ndataset B, we sampled an iso-surface generated
by Dominique Attali. The volume data\r\nTopological Persistence and Simplification
533 was provided by Francoise Peyrin from CNRS CREATIS in Lyon and was issued from
¸ Synchrotron Radiation Microtomography from the ID19 beamline at ESRF in Grenoble.\r\nWe
generated Fig. 17 using the Protein Explorer [6]."
article_processing_charge: No
article_type: original
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: David
full_name: Letscher, David
last_name: Letscher
- first_name: Afra
full_name: Zomorodian, Afra
last_name: Zomorodian
citation:
ama: Edelsbrunner H, Letscher D, Zomorodian A. Topological persistence and simplification.
Discrete & Computational Geometry. 2002;28(4):511-533. doi:10.1007/s00454-002-2885-2
apa: Edelsbrunner, H., Letscher, D., & Zomorodian, A. (2002). Topological persistence
and simplification. Discrete & Computational Geometry. Springer. https://doi.org/10.1007/s00454-002-2885-2
chicago: Edelsbrunner, Herbert, David Letscher, and Afra Zomorodian. “Topological
Persistence and Simplification.” Discrete & Computational Geometry.
Springer, 2002. https://doi.org/10.1007/s00454-002-2885-2.
ieee: H. Edelsbrunner, D. Letscher, and A. Zomorodian, “Topological persistence
and simplification,” Discrete & Computational Geometry, vol. 28, no.
4. Springer, pp. 511–533, 2002.
ista: Edelsbrunner H, Letscher D, Zomorodian A. 2002. Topological persistence and
simplification. Discrete & Computational Geometry. 28(4), 511–533.
mla: Edelsbrunner, Herbert, et al. “Topological Persistence and Simplification.”
Discrete & Computational Geometry, vol. 28, no. 4, Springer, 2002,
pp. 511–33, doi:10.1007/s00454-002-2885-2.
short: H. Edelsbrunner, D. Letscher, A. Zomorodian, Discrete & Computational
Geometry 28 (2002) 511–533.
date_created: 2018-12-11T12:06:20Z
date_published: 2002-12-01T00:00:00Z
date_updated: 2023-06-13T11:41:19Z
day: '01'
doi: 10.1007/s00454-002-2885-2
extern: '1'
intvolume: ' 28'
issue: '4'
language:
- iso: eng
month: '12'
oa_version: None
page: 511 - 533
publication: Discrete & Computational Geometry
publication_identifier:
issn:
- 0179-5376
publication_status: published
publisher: Springer
publist_id: '2130'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Topological persistence and simplification
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 28
year: '2002'
...
---
_id: '3920'
abstract:
- lang: eng
text: A particular Solid Injector needle, suitable for GC-MS analyses of small specimens,
is described together with its application in a study on ants.
acknowledgement: "We thank Giancarlo Bucelli and Gloriano Moneti (Centro Interdipartimentale\r\ndi
Spettrometria di Massa, Università di Firenze) for their help. Funding was\r\nprovided
by the MURST “60%” and Italian CNR “40%” funds, as well as through\r\nthe research
network “Social evolution” of the Universities of Aarhus, Firenze,\r\nKeele, Sheffield,
Uppsala, Würzburg and the ETH of Zürich financed by the\r\nEuropean commission via
the Training and Mobility of Researchers (TMR)\r\nprogramme. "
article_processing_charge: No
article_type: original
author:
- first_name: Stefano
full_name: Turillazzi, Stefano
last_name: Turillazzi
- first_name: Matthew
full_name: Sledge, Matthew
last_name: Sledge
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
- first_name: Jürgen
full_name: Heinze, Jürgen
last_name: Heinze
citation:
ama: Turillazzi S, Sledge M, Cremer S, Heinze J. A method for analysing small-size
specimens in GC-MS. Insect Social Life. 2002;4:169-175.
apa: Turillazzi, S., Sledge, M., Cremer, S., & Heinze, J. (2002). A method for
analysing small-size specimens in GC-MS. Insect Social Life. Elsevier.
chicago: Turillazzi, Stefano, Matthew Sledge, Sylvia Cremer, and Jürgen Heinze.
“A Method for Analysing Small-Size Specimens in GC-MS.” Insect Social Life.
Elsevier, 2002.
ieee: S. Turillazzi, M. Sledge, S. Cremer, and J. Heinze, “A method for analysing
small-size specimens in GC-MS,” Insect Social Life, vol. 4. Elsevier, pp.
169–175, 2002.
ista: Turillazzi S, Sledge M, Cremer S, Heinze J. 2002. A method for analysing small-size
specimens in GC-MS. Insect Social Life. 4, 169–175.
mla: Turillazzi, Stefano, et al. “A Method for Analysing Small-Size Specimens in
GC-MS.” Insect Social Life, vol. 4, Elsevier, 2002, pp. 169–75.
short: S. Turillazzi, M. Sledge, S. Cremer, J. Heinze, Insect Social Life 4 (2002)
169–175.
date_created: 2018-12-11T12:05:54Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-06-13T12:57:06Z
day: '01'
extern: '1'
intvolume: ' 4'
language:
- iso: eng
month: '01'
oa_version: None
page: 169 - 175
publication: Insect Social Life
publication_status: published
publisher: Elsevier
publist_id: '2232'
quality_controlled: '1'
status: public
title: A method for analysing small-size specimens in GC-MS
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 4
year: '2002'
...
---
_id: '3800'
abstract:
- lang: eng
text: Networks of GABAergic interneurons are of critical importance for the generation
of gamma frequency oscillations in the brain. To examine the underlying synaptic
mechanisms, we made paired recordings from "basket cells" (BCs) in different
subfields of hippocampal slices, using transgenic mice that express enhanced green
fluorescent protein (EGFP) under the control of the parvalbumin promoter. Unitary
inhibitory postsynaptic currents (IPSCs) showed large amplitude and fast time
course with mean amplitude-weighted decay time constants of 2.5, 1.2, and 1.8
ms in the dentate gyrus, and the cornu ammonis area 3 (CA3) and 1 (CA1), respectively
(33-34 degrees C). The decay of unitary IPSCs at BC-BC synapses was significantly
faster than that at BC-principal cell synapses, indicating target cell-specific
differences in IPSC kinetics. In addition, electrical coupling was found in a
subset of BC-BC pairs. To examine whether an interneuron network with fast inhibitory
synapses can act as a gamma frequency oscillator, we developed an interneuron
network model based on experimentally determined properties. In comparison to
previous interneuron network models, our model was able to generate oscillatory
activity with higher coherence over a broad range of frequencies (20-110 Hz).
In this model, high coherence and flexibility in frequency control emerge from
the combination of synaptic properties, network structure, and electrical coupling.
acknowledgement: We thank Drs. J. Bischofberger, M. Heckmann, and R. Traub for critically
reading the manuscript. This work was supported by Deutsche Forschungsgemeinschaft
Grants SFB 505/C5 (to P.J.) and SFB 505/C6 (to M.F. and P.J.), Human Frontiers Science
Program Organization Grant RG0017/1998-B (to P.J.), and grants from the Alexander-von-Humboldt
Foundation (to P.J. and M.F.), the Schilling Foundation (to H.M.), and Novartis
(to H.M.).
article_processing_charge: No
article_type: original
author:
- first_name: Marlene
full_name: Bartos, Marlene
last_name: Bartos
- first_name: Imre
full_name: Vida, Imre
last_name: Vida
- first_name: Michael
full_name: Frotscher, Michael
last_name: Frotscher
- first_name: Axel
full_name: Meyer, Axel
last_name: Meyer
- first_name: Hannah
full_name: Monyer, Hannah
last_name: Monyer
- first_name: Jörg
full_name: Geiger, Jörg
last_name: Geiger
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Bartos M, Vida I, Frotscher M, et al. Fast synaptic inhibition promotes synchronized
gamma oscillations in hippocampal interneuron networks. PNAS. 2002;99(20):13222-13227.
doi:10.1073/pnas.192233099
apa: Bartos, M., Vida, I., Frotscher, M., Meyer, A., Monyer, H., Geiger, J., &
Jonas, P. M. (2002). Fast synaptic inhibition promotes synchronized gamma oscillations
in hippocampal interneuron networks. PNAS. National Academy of Sciences.
https://doi.org/10.1073/pnas.192233099
chicago: Bartos, Marlene, Imre Vida, Michael Frotscher, Axel Meyer, Hannah Monyer,
Jörg Geiger, and Peter M Jonas. “Fast Synaptic Inhibition Promotes Synchronized
Gamma Oscillations in Hippocampal Interneuron Networks.” PNAS. National
Academy of Sciences, 2002. https://doi.org/10.1073/pnas.192233099.
ieee: M. Bartos et al., “Fast synaptic inhibition promotes synchronized gamma
oscillations in hippocampal interneuron networks,” PNAS, vol. 99, no. 20.
National Academy of Sciences, pp. 13222–13227, 2002.
ista: Bartos M, Vida I, Frotscher M, Meyer A, Monyer H, Geiger J, Jonas PM. 2002.
Fast synaptic inhibition promotes synchronized gamma oscillations in hippocampal
interneuron networks. PNAS. 99(20), 13222–13227.
mla: Bartos, Marlene, et al. “Fast Synaptic Inhibition Promotes Synchronized Gamma
Oscillations in Hippocampal Interneuron Networks.” PNAS, vol. 99, no. 20,
National Academy of Sciences, 2002, pp. 13222–27, doi:10.1073/pnas.192233099.
short: M. Bartos, I. Vida, M. Frotscher, A. Meyer, H. Monyer, J. Geiger, P.M. Jonas,
PNAS 99 (2002) 13222–13227.
date_created: 2018-12-11T12:05:14Z
date_published: 2002-09-16T00:00:00Z
date_updated: 2023-07-10T13:35:18Z
day: '16'
doi: 10.1073/pnas.192233099
extern: '1'
external_id:
pmid:
- '12235359'
intvolume: ' 99'
issue: '20'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC130614/
month: '09'
oa: 1
oa_version: Published Version
page: 13222 - 13227
pmid: 1
publication: PNAS
publication_identifier:
issn:
- 0027-8424
publication_status: published
publisher: National Academy of Sciences
publist_id: '2409'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Fast synaptic inhibition promotes synchronized gamma oscillations in hippocampal
interneuron networks
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 99
year: '2002'
...
---
_id: '3803'
abstract:
- lang: eng
text: Mossy fiber (MF) synapses are key stations for flow of information through
the hippocampal formation. A major component of the output of the MF system is
directed towards inhibitory interneurons. Recent studies have revealed that the
functional properties of MF-interneuron synapses differ substantially from those
of MF-CA3 pyramidal neuron synapses. Mossy-fiber-interneuron synapses in the stratum
lucidum represent a continuum of functional subtypes, in which the subunit composition
of postsynaptic AMPA receptors and NMDA receptors appears to be regulated in a
coordinated manner.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Josef
full_name: Bischofberger, Josef
last_name: Bischofberger
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: 'Bischofberger J, Jonas PM. TwoB or not twoB: differential transmission at
glutamatergic mossy fiber-interneuron synapses in the hippocampus. Trends in
Neurosciences. 2002;25(12):600-603. doi:10.1016/S0166-2236(02)02259-2'
apa: 'Bischofberger, J., & Jonas, P. M. (2002). TwoB or not twoB: differential
transmission at glutamatergic mossy fiber-interneuron synapses in the hippocampus.
Trends in Neurosciences. Elsevier. https://doi.org/10.1016/S0166-2236(02)02259-2'
chicago: 'Bischofberger, Josef, and Peter M Jonas. “TwoB or Not TwoB: Differential
Transmission at Glutamatergic Mossy Fiber-Interneuron Synapses in the Hippocampus.”
Trends in Neurosciences. Elsevier, 2002. https://doi.org/10.1016/S0166-2236(02)02259-2.'
ieee: 'J. Bischofberger and P. M. Jonas, “TwoB or not twoB: differential transmission
at glutamatergic mossy fiber-interneuron synapses in the hippocampus,” Trends
in Neurosciences, vol. 25, no. 12. Elsevier, pp. 600–603, 2002.'
ista: 'Bischofberger J, Jonas PM. 2002. TwoB or not twoB: differential transmission
at glutamatergic mossy fiber-interneuron synapses in the hippocampus. Trends in
Neurosciences. 25(12), 600–603.'
mla: 'Bischofberger, Josef, and Peter M. Jonas. “TwoB or Not TwoB: Differential
Transmission at Glutamatergic Mossy Fiber-Interneuron Synapses in the Hippocampus.”
Trends in Neurosciences, vol. 25, no. 12, Elsevier, 2002, pp. 600–03, doi:10.1016/S0166-2236(02)02259-2.'
short: J. Bischofberger, P.M. Jonas, Trends in Neurosciences 25 (2002) 600–603.
date_created: 2018-12-11T12:05:15Z
date_published: 2002-12-01T00:00:00Z
date_updated: 2023-07-10T13:22:24Z
day: '01'
doi: 10.1016/S0166-2236(02)02259-2
extern: '1'
external_id:
pmid:
- '12446120'
intvolume: ' 25'
issue: '12'
language:
- iso: eng
month: '12'
oa_version: None
page: 600 - 603
pmid: 1
publication: Trends in Neurosciences
publication_identifier:
issn:
- 0166-2236
publication_status: published
publisher: Elsevier
publist_id: '2408'
quality_controlled: '1'
status: public
title: 'TwoB or not twoB: differential transmission at glutamatergic mossy fiber-interneuron
synapses in the hippocampus'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 25
year: '2002'
...
---
_id: '3801'
abstract:
- lang: eng
text: 'To examine possible interactions between fast depression and modulation of
inhibitory synaptic transmission in the hippocampus, we recorded from pairs of
synaptically connected basket cells (BCs) and granule cells (GCs) in the dentate
gyrus of rat brain slices at 34 degrees C. Multiple-pulse depression (MPD) was
examined in trains of 5 or 10 inhibitory postsynaptic currents (IPSCs) evoked
at frequencies of 10-100 Hz under several conditions that inhibit transmitter
release: block of voltage-dependent Ca2+ channels by Cd2+ (10 microM), activation
of gamma-amino-butyric acid type B receptors (GABA(B)Rs) by baclofen (10 microM)
and activation of muscarinic acetylcholine receptors (mAchRs) by carbachol (2
microM). All manipulations led to a substantial inhibition of synaptic transmission,
reducing the amplitude of the first IPSC in the train (IPSC1) by 72%, 61% and
29%, respectively. However, MPD was largely preserved under these conditions (0.34
in control versus 0.31, 0.50 and 0.47 in the respective conditions at 50 Hz).
Similarly, a theta burst stimulation (TBS) protocol reduced IPSC1 by 54%, but
left MPD unchanged (0.40 in control and 0.39 during TBS). Analysis of both fractions
of transmission failures and coefficients of variation (CV) of IPSC peak amplitudes
suggested that MPD had a presynaptic expression site, independent of release probability.
In conclusion, different types of presynaptic modulation of inhibitory synaptic
transmission converge on a reduction of synaptic strength, while short-term dynamics
are largely unchanged.'
acknowledgement: We thank Drs M. Bartos, J. Bischofberger, M. Heckmann and
I. Vida for critically reading the manuscript, Dr K. Götz for providing information about pharmacological properties of
inhibitory hippocampal synapses, and A. Blomenkamp and K. Winterhalter for
technical assistance. This work was supported by Deutsche Forschungsgemeinschaft
grants to P.J. (Jo-248/2-2,SFB 505/C5) and the Alexander-von-Humboldt foundation.
article_processing_charge: No
article_type: original
author:
- first_name: Stefan
full_name: Hefft, Stefan
last_name: Hefft
- first_name: Udo
full_name: Kraushaar, Udo
last_name: Kraushaar
- first_name: Jörg
full_name: Geiger, Jörg
last_name: Geiger
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Hefft S, Kraushaar U, Geiger J, Jonas PM. Presynaptic short-term depression
is maintained during regulation of transmitter release at a GABAergic synapse
in rat hippocampus. Journal of Physiology. 2002;539(Pt 1):201-208. doi:10.1113/jphysiol.2001.013455
apa: Hefft, S., Kraushaar, U., Geiger, J., & Jonas, P. M. (2002). Presynaptic
short-term depression is maintained during regulation of transmitter release at
a GABAergic synapse in rat hippocampus. Journal of Physiology. Wiley-Blackwell.
https://doi.org/10.1113/jphysiol.2001.013455
chicago: Hefft, Stefan, Udo Kraushaar, Jörg Geiger, and Peter M Jonas. “Presynaptic
Short-Term Depression Is Maintained during Regulation of Transmitter Release at
a GABAergic Synapse in Rat Hippocampus.” Journal of Physiology. Wiley-Blackwell,
2002. https://doi.org/10.1113/jphysiol.2001.013455.
ieee: S. Hefft, U. Kraushaar, J. Geiger, and P. M. Jonas, “Presynaptic short-term
depression is maintained during regulation of transmitter release at a GABAergic
synapse in rat hippocampus,” Journal of Physiology, vol. 539, no. Pt 1.
Wiley-Blackwell, pp. 201–8, 2002.
ista: Hefft S, Kraushaar U, Geiger J, Jonas PM. 2002. Presynaptic short-term depression
is maintained during regulation of transmitter release at a GABAergic synapse
in rat hippocampus. Journal of Physiology. 539(Pt 1), 201–8.
mla: Hefft, Stefan, et al. “Presynaptic Short-Term Depression Is Maintained during
Regulation of Transmitter Release at a GABAergic Synapse in Rat Hippocampus.”
Journal of Physiology, vol. 539, no. Pt 1, Wiley-Blackwell, 2002, pp. 201–08,
doi:10.1113/jphysiol.2001.013455.
short: S. Hefft, U. Kraushaar, J. Geiger, P.M. Jonas, Journal of Physiology 539
(2002) 201–8.
date_created: 2018-12-11T12:05:15Z
date_published: 2002-02-01T00:00:00Z
date_updated: 2023-07-11T10:01:12Z
day: '01'
doi: 10.1113/jphysiol.2001.013455
extern: '1'
external_id:
pmid:
- '11850513'
intvolume: ' 539'
issue: Pt 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290140/
month: '02'
oa: 1
oa_version: Published Version
page: 201 - 8
pmid: 1
publication: Journal of Physiology
publication_identifier:
issn:
- 0022-3751
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2410'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Presynaptic short-term depression is maintained during regulation of transmitter
release at a GABAergic synapse in rat hippocampus
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 539
year: '2002'
...
---
_id: '3799'
abstract:
- lang: eng
text: 'GABAergic interneurones are diverse in their morphological and functional
properties. Perisomatic inhibitory cells show fast spiking during sustained current
injection, whereas dendritic inhibitory cells fire action potentials with lower
frequency. We examined functional and molecular properties of K(+) channels in
interneurones with horizontal dendrites in stratum oriens-alveus (OA) of the hippocampal
CA1 region, which mainly comprise somatostatin-positive dendritic inhibitory cells.
Voltage-gated K(+) currents in nucleated patches isolated from OA interneurones
consisted of three major components: a fast delayed rectifier K(+) current component
that was highly sensitive to external 4-aminopyridine (4-AP) and tetraethylammonium
(TEA) (half-maximal inhibitory concentrations < 0.1 mM for both blockers),
a slow delayed rectifier K(+) current component that was sensitive to high concentrations
of TEA, but insensitive to 4-AP, and a rapidly inactivating A-type K(+) current
component that was blocked by high concentrations of 4-AP, but resistant to TEA.
The relative contributions of these components to the macroscopic K(+) current
were estimated as 57 +/- 5, 25 +/- 6, and 19 +/- 2 %, respectively. Dendrotoxin,
a selective blocker of Kv1 channels had only minimal effects on K(+) currents
in nucleated patches. Coapplication of the membrane-permeant cAMP analogue 8-(4-chlorophenylthio)-adenosine
3'':5''-cyclic monophosphate (cpt-cAMP) and the phosphodiesterase blocker isobutyl-methylxanthine
(IBMX) resulted in a selective inhibition of the fast delayed rectifier K(+) current
component. This inhibition was absent in the presence of the protein kinase A
(PKA) inhibitor H-89, implying the involvement of PKA-mediated phosphorylation.
Single-cell reverse transcription-polymerase chain reaction (RT-PCR) analysis
revealed a high abundance of Kv3.2 mRNA in OA interneurones, whereas the expression
level of Kv3.1 mRNA was markedly lower. Similarly, RT-PCR analysis showed a high
abundance of Kv4.3 mRNA, whereas Kv4.2 mRNA was undetectable. This suggests that
the fast delayed rectifier K(+) current and the A-type K(+) current component
are mediated predominantly by homomeric Kv3.2 and Kv4.3 channels. Selective modulation
of Kv3.2 channels in OA interneurones by cAMP is likely to be an important factor
regulating the activity of dendritic inhibitory cells in principal neurone-interneurone
microcircuits.'
acknowledgement: We thank Drs J. Bischofberger, M. Heckmann, and I. Vida for critically
reading the manuscript, and A. Blomenkamp and K. Winterhalter for technical assistance.
This work was supported by a scholarship from the Deutscher Akademischer Austansch
dienst to C.-C. L., a Deutsche Forschungsgemeinschaft grant to P. J. (SFB 505/C5),
and the Alexander-von-Humboldt foundation.
article_processing_charge: No
article_type: original
author:
- first_name: Cheng
full_name: Lien, Cheng
last_name: Lien
- first_name: Marco
full_name: Martina, Marco
last_name: Martina
- first_name: Jobst
full_name: Schultz, Jobst
last_name: Schultz
- first_name: Heimo
full_name: Ehmke, Heimo
last_name: Ehmke
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Lien C, Martina M, Schultz J, Ehmke H, Jonas PM. Gating, modulation and subunit
composition of voltage-gated K(+) channels in dendritic inhibitory interneurones
of rat hippocampus. Journal of Physiology. 2002;538(Pt 2):405-419. doi:10.1113/jphysiol.2001.013066
apa: Lien, C., Martina, M., Schultz, J., Ehmke, H., & Jonas, P. M. (2002). Gating,
modulation and subunit composition of voltage-gated K(+) channels in dendritic
inhibitory interneurones of rat hippocampus. Journal of Physiology. Wiley-Blackwell.
https://doi.org/10.1113/jphysiol.2001.013066
chicago: Lien, Cheng, Marco Martina, Jobst Schultz, Heimo Ehmke, and Peter M Jonas.
“Gating, Modulation and Subunit Composition of Voltage-Gated K(+) Channels in
Dendritic Inhibitory Interneurones of Rat Hippocampus.” Journal of Physiology.
Wiley-Blackwell, 2002. https://doi.org/10.1113/jphysiol.2001.013066.
ieee: C. Lien, M. Martina, J. Schultz, H. Ehmke, and P. M. Jonas, “Gating, modulation
and subunit composition of voltage-gated K(+) channels in dendritic inhibitory
interneurones of rat hippocampus,” Journal of Physiology, vol. 538, no.
Pt 2. Wiley-Blackwell, pp. 405–419, 2002.
ista: Lien C, Martina M, Schultz J, Ehmke H, Jonas PM. 2002. Gating, modulation
and subunit composition of voltage-gated K(+) channels in dendritic inhibitory
interneurones of rat hippocampus. Journal of Physiology. 538(Pt 2), 405–419.
mla: Lien, Cheng, et al. “Gating, Modulation and Subunit Composition of Voltage-Gated
K(+) Channels in Dendritic Inhibitory Interneurones of Rat Hippocampus.” Journal
of Physiology, vol. 538, no. Pt 2, Wiley-Blackwell, 2002, pp. 405–19, doi:10.1113/jphysiol.2001.013066.
short: C. Lien, M. Martina, J. Schultz, H. Ehmke, P.M. Jonas, Journal of Physiology
538 (2002) 405–419.
date_created: 2018-12-11T12:05:14Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-07-11T12:32:26Z
day: '01'
doi: 10.1113/jphysiol.2001.013066
extern: '1'
external_id:
pmid:
- '11790809'
intvolume: ' 538'
issue: Pt 2
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290075/
month: '01'
oa: 1
oa_version: Published Version
page: 405 - 419
pmid: 1
publication: Journal of Physiology
publication_identifier:
issn:
- 0022-3751
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2411'
quality_controlled: '1'
status: public
title: Gating, modulation and subunit composition of voltage-gated K(+) channels in
dendritic inhibitory interneurones of rat hippocampus
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 538
year: '2002'
...
---
_id: '3621'
abstract:
- lang: eng
text: In 1991, Barton and Turelli developed recursions to describe the evolution
of multilocus systems under arbitrary forms of selection. This article generalizes
their approach to allow for arbitrary modes of inheritance, including diploidy,
polyploidy, sex linkage, cytoplasmic inheritance, and genomic imprinting. The
framework is also extended to allow for other deterministic evolutionary forces,
including migration and mutation. Exact recursions that fully describe the state
of the population are presented; these are implemented in a computer algebra package
(available on the Web at http://helios.bto.ed.ac.uk/evolgen). Despite the generality
of our framework, it can describe evolutionary dynamics exactly by just two equations.
These recursions can be further simplified using a "quasi-linkage equilibrium"
(QLE) approximation. We illustrate the methods by finding the effect of natural
selection, sexual selection, mutation, and migration on the genetic composition
of a population.
article_processing_charge: No
article_type: original
author:
- first_name: Mark
full_name: Kirkpatrick, Mark
last_name: Kirkpatrick
- first_name: Toby
full_name: Johnson, Toby
last_name: Johnson
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Kirkpatrick M, Johnson T, Barton NH. General models of multilocus evolution.
Genetics. 2002;161(4):1727-1750. doi:10.1093/genetics/161.4.1727
apa: Kirkpatrick, M., Johnson, T., & Barton, N. H. (2002). General models of
multilocus evolution. Genetics. Genetics Society of America. https://doi.org/10.1093/genetics/161.4.1727
chicago: Kirkpatrick, Mark, Toby Johnson, and Nicholas H Barton. “General Models
of Multilocus Evolution.” Genetics. Genetics Society of America, 2002.
https://doi.org/10.1093/genetics/161.4.1727.
ieee: M. Kirkpatrick, T. Johnson, and N. H. Barton, “General models of multilocus
evolution,” Genetics, vol. 161, no. 4. Genetics Society of America, pp.
1727–1750, 2002.
ista: Kirkpatrick M, Johnson T, Barton NH. 2002. General models of multilocus evolution.
Genetics. 161(4), 1727–1750.
mla: Kirkpatrick, Mark, et al. “General Models of Multilocus Evolution.” Genetics,
vol. 161, no. 4, Genetics Society of America, 2002, pp. 1727–50, doi:10.1093/genetics/161.4.1727.
short: M. Kirkpatrick, T. Johnson, N.H. Barton, Genetics 161 (2002) 1727–1750.
date_created: 2018-12-11T12:04:17Z
date_published: 2002-08-01T00:00:00Z
date_updated: 2023-07-11T13:20:26Z
day: '01'
doi: 10.1093/genetics/161.4.1727
extern: '1'
external_id:
pmid:
- '12196414'
intvolume: ' 161'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462196/
month: '08'
oa: 1
oa_version: Published Version
page: 1727 - 1750
pmid: 1
publication: Genetics
publication_identifier:
issn:
- 0016-6731
publication_status: published
publisher: Genetics Society of America
publist_id: '2762'
quality_controlled: '1'
scopus_import: '1'
status: public
title: General models of multilocus evolution
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 161
year: '2002'
...
---
_id: '3757'
abstract:
- lang: eng
text: A central problem in biology is determining how genes interact as parts of
functional networks. Creation and analysis of synthetic networks, composed of
well-characterized genetic elements, provide a framework for theoretical modeling.
Here, with the use of a combinatorial method, a library of networks with varying
connectivity was generated in Escherichia coli. These networks were composed of
genes encoding the transcriptional regulators Lacl, TetR, and lambda Cl, as well
as the corresponding promoters. They displayed phenotypic behaviors resembling
binary logical circuits, with two chemical “inputs” and a fluorescent protein
“output.” Within this simple system, diverse computational functions arose through
changes in network connectivity. Combinatorial synthesis provides an alternative
approach for studying biological networks, as well as an efficient method for
producing diverse phenotypes in vivo.
article_processing_charge: No
article_type: original
author:
- first_name: Calin C
full_name: Guet, Calin C
id: 47F8433E-F248-11E8-B48F-1D18A9856A87
last_name: Guet
orcid: 0000-0001-6220-2052
- first_name: Michael
full_name: Elowitz, Michael
last_name: Elowitz
- first_name: Weihong
full_name: Hsing, Weihong
last_name: Hsing
- first_name: Stanislas
full_name: Leibler, Stanislas
last_name: Leibler
citation:
ama: Guet CC, Elowitz M, Hsing W, Leibler S. Combinatorial synthesis of genetic
networks. Science. 2002;296(5572):1466-1470. doi:10.1126/science.1067407
apa: Guet, C. C., Elowitz, M., Hsing, W., & Leibler, S. (2002). Combinatorial
synthesis of genetic networks. Science. American Association for the Advancement
of Science. https://doi.org/10.1126/science.1067407
chicago: Guet, Calin C, Michael Elowitz, Weihong Hsing, and Stanislas Leibler. “Combinatorial
Synthesis of Genetic Networks.” Science. American Association for the Advancement
of Science, 2002. https://doi.org/10.1126/science.1067407.
ieee: C. C. Guet, M. Elowitz, W. Hsing, and S. Leibler, “Combinatorial synthesis
of genetic networks,” Science, vol. 296, no. 5572. American Association
for the Advancement of Science, pp. 1466–1470, 2002.
ista: Guet CC, Elowitz M, Hsing W, Leibler S. 2002. Combinatorial synthesis of genetic
networks. Science. 296(5572), 1466–1470.
mla: Guet, Calin C., et al. “Combinatorial Synthesis of Genetic Networks.” Science,
vol. 296, no. 5572, American Association for the Advancement of Science, 2002,
pp. 1466–70, doi:10.1126/science.1067407.
short: C.C. Guet, M. Elowitz, W. Hsing, S. Leibler, Science 296 (2002) 1466–1470.
date_created: 2018-12-11T12:05:00Z
date_published: 2002-05-24T00:00:00Z
date_updated: 2023-07-11T12:48:53Z
day: '24'
doi: 10.1126/science.1067407
extern: '1'
external_id:
pmid:
- '12029133'
intvolume: ' 296'
issue: '5572'
language:
- iso: eng
month: '05'
oa_version: None
page: 1466 - 1470
pmid: 1
publication: Science
publication_identifier:
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '2471'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Combinatorial synthesis of genetic networks
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 296
year: '2002'
...
---
_id: '3497'
abstract:
- lang: eng
text: The use of advanced patch-clamp recording techniques in brain slices, such
as simultaneous recording from multiple neurons and recording from dendrites or
presynaptic terminals, demands slices of the highest quality. In this context
the mechanics of the tissue slicer are an important factor. Ideally, a tissue
slicer should generate large-amplitude and high-frequency movements of the cutting
blade in a horizontal axis, with minimal vibrations in the vertical axis. We developed
a vibroslicer that fulfils these in part conflicting requirements. The oscillator
is a permanent-magnet-coil-leaf-spring system. Using an auto-resonant mechano-electrical
feedback circuit, large horizontal oscillations (up to 3 mm peak-to-peak) with
high frequency (,90 Hz) are generated. To minimize vertical vibrations, an adjustment
mechanism was employed that allowed alignment of the cutting edge of the blade
with the major axis of the oscillation. A vibroprobe device was used to monitor
vertical vibrations during adjustment. The system is based on the shading of the
light path between a light-emitting diode (LED) and a photodiode. Vibroprobe monitoring
revealed that the vibroslicer, after appropriate adjustment, generated vertical
vibrations of <1 µm, significantly less than many commercial tissue slicers.
Light- and electron-microscopic analysis of surface layers of slices cut with
the vibroslicer showed that cellular elements, dendritic processes and presynaptic
terminals are well preserved under these conditions, as required for patch-clamp
recording from these structures.
acknowledgement: "We thank Dr. M. Frotscher for reading the manuscript, and H. Kressner,
R. Laufersweiler, and A. Bühler for help with the construction of several prototypes
of vibroslicer and vibroprobe. We also thank A. Blomenkamp, K. Winterhalter, B.
Joch, and A. Schneider for technical assistance. This work was supported by grants
of the Deutsche Forschungsgemeinschaft\r\n(SFB 505/C5, C6) and the Human Frontiers
Science Program Organization (RG0017/1998-B)."
article_processing_charge: No
article_type: original
author:
- first_name: Jörg
full_name: Geiger, Jörg
last_name: Geiger
- first_name: Joseph
full_name: Bischofberger, Joseph
last_name: Bischofberger
- first_name: Imre
full_name: Vida, Imre
last_name: Vida
- first_name: Ulrich
full_name: Fröbe, Ulrich
last_name: Fröbe
- first_name: S
full_name: Pfitzinger, S
last_name: Pfitzinger
- first_name: H.
full_name: Weber, H.
last_name: Weber
- first_name: Klaus
full_name: Haverkampf, Klaus
last_name: Haverkampf
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: 'Geiger J, Bischofberger J, Vida I, et al. Patch-clamp recording in brain slices
with improved slicer technology. Pflugers Archiv : European Journal of Physiology.
2002;443(3):491-501. doi:10.1007/s00424-001-0735-3'
apa: 'Geiger, J., Bischofberger, J., Vida, I., Fröbe, U., Pfitzinger, S., Weber,
H., … Jonas, P. M. (2002). Patch-clamp recording in brain slices with improved
slicer technology. Pflugers Archiv : European Journal of Physiology. Springer.
https://doi.org/10.1007/s00424-001-0735-3'
chicago: 'Geiger, Jörg, Joseph Bischofberger, Imre Vida, Ulrich Fröbe, S Pfitzinger,
H. Weber, Klaus Haverkampf, and Peter M Jonas. “Patch-Clamp Recording in Brain
Slices with Improved Slicer Technology.” Pflugers Archiv : European Journal
of Physiology. Springer, 2002. https://doi.org/10.1007/s00424-001-0735-3.'
ieee: 'J. Geiger et al., “Patch-clamp recording in brain slices with improved
slicer technology,” Pflugers Archiv : European Journal of Physiology, vol.
443, no. 3. Springer, pp. 491–501, 2002.'
ista: 'Geiger J, Bischofberger J, Vida I, Fröbe U, Pfitzinger S, Weber H, Haverkampf
K, Jonas PM. 2002. Patch-clamp recording in brain slices with improved slicer
technology. Pflugers Archiv : European Journal of Physiology. 443(3), 491–501.'
mla: 'Geiger, Jörg, et al. “Patch-Clamp Recording in Brain Slices with Improved
Slicer Technology.” Pflugers Archiv : European Journal of Physiology, vol.
443, no. 3, Springer, 2002, pp. 491–501, doi:10.1007/s00424-001-0735-3.'
short: 'J. Geiger, J. Bischofberger, I. Vida, U. Fröbe, S. Pfitzinger, H. Weber,
K. Haverkampf, P.M. Jonas, Pflugers Archiv : European Journal of Physiology 443
(2002) 491–501.'
date_created: 2018-12-11T12:03:38Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-07-17T07:36:37Z
day: '01'
doi: 10.1007/s00424-001-0735-3
extern: '1'
external_id:
pmid:
- '11810221'
intvolume: ' 443'
issue: '3'
language:
- iso: eng
month: '01'
oa_version: None
page: 491 - 501
pmid: 1
publication: 'Pflugers Archiv : European Journal of Physiology'
publication_identifier:
issn:
- 0031-6768
publication_status: published
publisher: Springer
publist_id: '2890'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Patch-clamp recording in brain slices with improved slicer technology
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 443
year: '2002'
...
---
_id: '3533'
abstract:
- lang: eng
text: 'Information in neuronal networks is thought to be represented by the rate
of discharge and the temporal relationship between the discharging neurons. The
discharge frequency of neurons is affected by their afferents and intrinsic properties,
and shows great individual variability. The temporal coordination of neurons is
greatly facilitated by network oscillations. In the hippocampus, population synchrony
fluctuates during theta and gamma oscillations (10-100 ms scale) and can increase
almost 10-fold during sharp wave bursts. Despite these large changes in excitability
in the sub-second scale, longer-term (minute-scale) firing rates of individual
neurons are relatively constant in an unchanging environment. As a result, mean
hippocampal output remains stable over time. To understand the mechanisms responsible
for this homeostasis, we address the following issues: (i) Can firing rates of
single cells be modified? (ii) Once modified, what mechanism(s) can maintain the
changes? We show that firing rates of hippocampal pyramidal cells can be altered
in a novel environment and by Hebbian pairing of physiological input patterns
with postsynaptic burst discharge. We also illustrate a competition between single
spikes and the occurrence of spike bursts. Since spike-inducing (suprathreshold)
inputs decrease the ability of strong (''teaching'') inputs to induce a burst
discharge, we propose that the single spike versus burst competition presents
a homeostatic regulatory mechanism to maintain synaptic strength and, consequently,
firing rate in pyramidal cells.'
article_processing_charge: No
article_type: original
author:
- first_name: György
full_name: Buzsáki, György
last_name: Buzsáki
- first_name: Jozsef L
full_name: Csicsvari, Jozsef L
id: 3FA14672-F248-11E8-B48F-1D18A9856A87
last_name: Csicsvari
orcid: 0000-0002-5193-4036
- first_name: George
full_name: Dragoi, George
last_name: Dragoi
- first_name: Kenneth
full_name: Harris, Kenneth
last_name: Harris
- first_name: D.
full_name: Henze, D.
last_name: Henze
- first_name: Hajima
full_name: Hirase, Hajima
last_name: Hirase
citation:
ama: Buzsáki G, Csicsvari JL, Dragoi G, Harris K, Henze D, Hirase H. Homeostatic
maintenance of neuronal excitability by burst discharges in vivo. Cerebral
Cortex. 2002;12(9):893-899. doi:10.1093/cercor/12.9.893
apa: Buzsáki, G., Csicsvari, J. L., Dragoi, G., Harris, K., Henze, D., & Hirase,
H. (2002). Homeostatic maintenance of neuronal excitability by burst discharges
in vivo. Cerebral Cortex. Oxford University Press. https://doi.org/10.1093/cercor/12.9.893
chicago: Buzsáki, György, Jozsef L Csicsvari, George Dragoi, Kenneth Harris, D.
Henze, and Hajima Hirase. “Homeostatic Maintenance of Neuronal Excitability by
Burst Discharges in Vivo.” Cerebral Cortex. Oxford University Press, 2002.
https://doi.org/10.1093/cercor/12.9.893.
ieee: G. Buzsáki, J. L. Csicsvari, G. Dragoi, K. Harris, D. Henze, and H. Hirase,
“Homeostatic maintenance of neuronal excitability by burst discharges in vivo,”
Cerebral Cortex, vol. 12, no. 9. Oxford University Press, pp. 893–899,
2002.
ista: Buzsáki G, Csicsvari JL, Dragoi G, Harris K, Henze D, Hirase H. 2002. Homeostatic
maintenance of neuronal excitability by burst discharges in vivo. Cerebral Cortex.
12(9), 893–899.
mla: Buzsáki, György, et al. “Homeostatic Maintenance of Neuronal Excitability by
Burst Discharges in Vivo.” Cerebral Cortex, vol. 12, no. 9, Oxford University
Press, 2002, pp. 893–99, doi:10.1093/cercor/12.9.893.
short: G. Buzsáki, J.L. Csicsvari, G. Dragoi, K. Harris, D. Henze, H. Hirase, Cerebral
Cortex 12 (2002) 893–899.
date_created: 2018-12-11T12:03:50Z
date_published: 2002-09-01T00:00:00Z
date_updated: 2023-07-17T07:27:12Z
day: '01'
doi: 10.1093/cercor/12.9.893
extern: '1'
external_id:
pmid:
- '12183388'
intvolume: ' 12'
issue: '9'
language:
- iso: eng
month: '09'
oa_version: None
page: 893 - 899
pmid: 1
publication: Cerebral Cortex
publication_identifier:
issn:
- 1047-3211
publication_status: published
publisher: Oxford University Press
publist_id: '2851'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Homeostatic maintenance of neuronal excitability by burst discharges in vivo
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 12
year: '2002'
...
---
_id: '3424'
abstract:
- lang: eng
text: "We give a brief overview of the current understanding of the explosion mechanism
of core collapse supernovae. Our main focus is the impact of rotation on the explosion.
Recent observations of the polarization of the light emitted by supernova explosions
indicate that there are large deviations from spherical symmetry in the very heart
of the explosion the origin of which is unknown. We use the new approach of a
three dimensional test particle based simulation to simulate the infall phase
of a supernova event. The underlying microphysics is simplified to make this computationally
possible. A systematic study of the influence of rotation mainly during the infall
phase of the collapse of a typical iron core is performed. Indications for significant
deviations from spherical symmetry are found in our very rapidly rotating models.
© 2002 American Institute of Physics\r\n"
alternative_title:
- Exotic Clustering, American Institute of Physics Conference Proceedings
article_processing_charge: No
author:
- first_name: Mark Tobias
full_name: Bollenbach, Mark Tobias
id: 3E6DB97A-F248-11E8-B48F-1D18A9856A87
last_name: Bollenbach
orcid: 0000-0003-4398-476X
- first_name: Wolfgang
full_name: Bauer, Wolfgang
last_name: Bauer
citation:
ama: 'Bollenbach MT, Bauer W. 3d supernovae collapse calculations. In: Vol 644.
American Institute of Physics; 2002:219-232. doi:10.1063/1.1523196 '
apa: 'Bollenbach, M. T., & Bauer, W. (2002). 3d supernovae collapse calculations
(Vol. 644, pp. 219–232). Presented at the CRIS: Catania Relativistic Ion Studies
, Catania, Italy: American Institute of Physics. https://doi.org/10.1063/1.1523196 '
chicago: Bollenbach, Mark Tobias, and Wolfgang Bauer. “3d Supernovae Collapse Calculations,”
644:219–32. American Institute of Physics, 2002. https://doi.org/10.1063/1.1523196 .
ieee: 'M. T. Bollenbach and W. Bauer, “3d supernovae collapse calculations,” presented
at the CRIS: Catania Relativistic Ion Studies , Catania, Italy, 2002, vol. 644,
pp. 219–232.'
ista: 'Bollenbach MT, Bauer W. 2002. 3d supernovae collapse calculations. CRIS:
Catania Relativistic Ion Studies , Exotic Clustering, American Institute of Physics
Conference Proceedings, vol. 644, 219–232.'
mla: Bollenbach, Mark Tobias, and Wolfgang Bauer. 3d Supernovae Collapse Calculations.
Vol. 644, American Institute of Physics, 2002, pp. 219–32, doi:10.1063/1.1523196 .
short: M.T. Bollenbach, W. Bauer, in:, American Institute of Physics, 2002, pp.
219–232.
conference:
end_date: 2002-06-14
location: Catania, Italy
name: 'CRIS: Catania Relativistic Ion Studies '
start_date: 2002-06-10
date_created: 2018-12-11T12:03:15Z
date_published: 2002-11-26T00:00:00Z
date_updated: 2023-07-17T11:05:27Z
day: '26'
doi: '10.1063/1.1523196 '
extern: '1'
intvolume: ' 644'
language:
- iso: eng
month: '11'
oa_version: None
page: 219 - 232
publication_identifier:
isbn:
- '9781510832008'
publication_status: published
publisher: American Institute of Physics
publist_id: '2977'
quality_controlled: '1'
status: public
title: 3d supernovae collapse calculations
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 644
year: '2002'
...
---
_id: '2988'
abstract:
- lang: eng
text: Coordination of cell and tissue polarity commonly involves directional signaling
[1]. In the Arabidopsis root epidermis, cell polarity is revealed by basal, root
tip-oriented, hair outgrowth from hair-forming cells (trichoblasts) [2]. The plant
hormone auxin displays polar movements [1, 3] and accumulates at maximum concentration
in the root tip [4, 5]. The application of polar auxin transport inhibitors [3]
evokes changes in trichoblast polarity only at high concentrations and after long-term
application [2, 4]. Thus, it remains open whether components of the auxin transport
machinery mediate establishment of trichoblast polarity. Here we report that the
presumptive auxin influx carrier AUX1 [6, 7] contributes to apical-basal hair
cell polarity. AUX1 function is required for polarity changes induced by exogenous
application of the auxin 2,4-D, a preferential influx carrier substrate. Similar
to aux1 mutants, the vesicle trafficking inhibitor brefeldin A (BFA) interferes
with polar hair initiation, and AUX1 function is required for BFA-mediated polarity
changes. Consistently, BFA inhibits membrane trafficking of AUX1, trichoblast
hyperpolarization induced by 2,4-D, and alters the distal auxin maximum. Our results
identify AUX1 as one component of a novel BFA-sensitive auxin transport pathway
polarizing cells toward a hormone maximum.
article_processing_charge: No
article_type: original
author:
- first_name: Markus
full_name: Grebe, Markus
last_name: Grebe
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Ranjan
full_name: Swarup, Ranjan
last_name: Swarup
- first_name: Karin
full_name: Ljung, Karin
last_name: Ljung
- first_name: Göran
full_name: Sandberg, Göran
last_name: Sandberg
- first_name: Maarten
full_name: Terlou, Maarten
last_name: Terlou
- first_name: Klaus
full_name: Palme, Klaus
last_name: Palme
- first_name: Malcolm
full_name: Bennett, Malcolm
last_name: Bennett
- first_name: Ben
full_name: Scheres, Ben
last_name: Scheres
citation:
ama: Grebe M, Friml J, Swarup R, et al. Cell polarity signaling in Arabidopsis involves
a BFA sensitive auxin influx pathway. Current Biology. 2002;12(4):329-334.
doi:10.1016/S0960-9822(02)00654-1
apa: Grebe, M., Friml, J., Swarup, R., Ljung, K., Sandberg, G., Terlou, M., … Scheres,
B. (2002). Cell polarity signaling in Arabidopsis involves a BFA sensitive auxin
influx pathway. Current Biology. Cell Press. https://doi.org/10.1016/S0960-9822(02)00654-1
chicago: Grebe, Markus, Jiří Friml, Ranjan Swarup, Karin Ljung, Göran Sandberg,
Maarten Terlou, Klaus Palme, Malcolm Bennett, and Ben Scheres. “Cell Polarity
Signaling in Arabidopsis Involves a BFA Sensitive Auxin Influx Pathway.” Current
Biology. Cell Press, 2002. https://doi.org/10.1016/S0960-9822(02)00654-1.
ieee: M. Grebe et al., “Cell polarity signaling in Arabidopsis involves a
BFA sensitive auxin influx pathway,” Current Biology, vol. 12, no. 4. Cell
Press, pp. 329–334, 2002.
ista: Grebe M, Friml J, Swarup R, Ljung K, Sandberg G, Terlou M, Palme K, Bennett
M, Scheres B. 2002. Cell polarity signaling in Arabidopsis involves a BFA sensitive
auxin influx pathway. Current Biology. 12(4), 329–334.
mla: Grebe, Markus, et al. “Cell Polarity Signaling in Arabidopsis Involves a BFA
Sensitive Auxin Influx Pathway.” Current Biology, vol. 12, no. 4, Cell
Press, 2002, pp. 329–34, doi:10.1016/S0960-9822(02)00654-1.
short: M. Grebe, J. Friml, R. Swarup, K. Ljung, G. Sandberg, M. Terlou, K. Palme,
M. Bennett, B. Scheres, Current Biology 12 (2002) 329–334.
date_created: 2018-12-11T12:00:43Z
date_published: 2002-02-19T00:00:00Z
date_updated: 2023-07-17T12:15:28Z
day: '19'
doi: 10.1016/S0960-9822(02)00654-1
extern: '1'
external_id:
pmid:
- '11864575'
intvolume: ' 12'
issue: '4'
language:
- iso: eng
month: '02'
oa_version: None
page: 329 - 334
pmid: 1
publication: Current Biology
publication_identifier:
issn:
- 0960-9822
publication_status: published
publisher: Cell Press
publist_id: '3714'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cell polarity signaling in Arabidopsis involves a BFA sensitive auxin influx
pathway
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 12
year: '2002'
...
---
_id: '3421'
abstract:
- lang: eng
text: Single molecule experiments provide insight into the individuality of biological
macromolecules, their unique function, reaction pathways, trajectories and molecular
interactions. The exceptional signal-to-noise ratio of the atomic force microscope
allows individual proteins to be imaged under physiologically relevant conditions
at a lateral resolution of 0.5–1 nm and a vertical resolution of 0.1–0.2 nm. Recently,
it has become possible to observe single molecule events using this technique.
This capability is reviewed on various water-soluble and membrane proteins. Examples
of the observation of function, variability, and assembly of single proteins are
discussed. Statistical analysis is important to extend conclusions derived from
single molecule experiments to protein species. Such approaches allow the classification
of protein conformations and movements. Recent developments of probe microscopy
techniques allow simultaneous measurement of multiple signals on individual macromolecules,
and greatly extend the range of experiments possible for probing biological systems
at the molecular level. Biologists exploring molecular mechanisms will benefit
from a burgeoning of scanning probe microscopes and of their future combination
with molecular biological experiments.
article_processing_charge: No
article_type: review
author:
- first_name: Daniel
full_name: Mueller, Daniel
last_name: Mueller
- first_name: Harald L
full_name: Janovjak, Harald L
id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
last_name: Janovjak
orcid: 0000-0002-8023-9315
- first_name: Tiina
full_name: Lehto, Tiina
last_name: Lehto
- first_name: Lars
full_name: Kuerschner, Lars
last_name: Kuerschner
- first_name: Kurt
full_name: Anderson, Kurt
last_name: Anderson
citation:
ama: Mueller D, Janovjak HL, Lehto T, Kuerschner L, Anderson K. Observing structure,
function and assembly of single proteins by AFM. Progress in Biophysics and
Molecular Biology. 2002;79(1-3):1-43. doi:10.1016/S0079-6107(02)00009-3
apa: Mueller, D., Janovjak, H. L., Lehto, T., Kuerschner, L., & Anderson, K.
(2002). Observing structure, function and assembly of single proteins by AFM.
Progress in Biophysics and Molecular Biology. Elsevier. https://doi.org/10.1016/S0079-6107(02)00009-3
chicago: Mueller, Daniel, Harald L Janovjak, Tiina Lehto, Lars Kuerschner, and Kurt
Anderson. “Observing Structure, Function and Assembly of Single Proteins by AFM.”
Progress in Biophysics and Molecular Biology. Elsevier, 2002. https://doi.org/10.1016/S0079-6107(02)00009-3.
ieee: D. Mueller, H. L. Janovjak, T. Lehto, L. Kuerschner, and K. Anderson, “Observing
structure, function and assembly of single proteins by AFM,” Progress in Biophysics
and Molecular Biology, vol. 79, no. 1–3. Elsevier, pp. 1–43, 2002.
ista: Mueller D, Janovjak HL, Lehto T, Kuerschner L, Anderson K. 2002. Observing
structure, function and assembly of single proteins by AFM. Progress in Biophysics
and Molecular Biology. 79(1–3), 1–43.
mla: Mueller, Daniel, et al. “Observing Structure, Function and Assembly of Single
Proteins by AFM.” Progress in Biophysics and Molecular Biology, vol. 79,
no. 1–3, Elsevier, 2002, pp. 1–43, doi:10.1016/S0079-6107(02)00009-3.
short: D. Mueller, H.L. Janovjak, T. Lehto, L. Kuerschner, K. Anderson, Progress
in Biophysics and Molecular Biology 79 (2002) 1–43.
date_created: 2018-12-11T12:03:14Z
date_published: 2002-05-01T00:00:00Z
date_updated: 2023-07-17T11:36:32Z
day: '01'
doi: 10.1016/S0079-6107(02)00009-3
extern: '1'
external_id:
pmid:
- '12225775'
intvolume: ' 79'
issue: 1-3
language:
- iso: eng
month: '05'
oa_version: None
page: 1 - 43
pmid: 1
publication: Progress in Biophysics and Molecular Biology
publication_identifier:
issn:
- 0079-6107
publication_status: published
publisher: Elsevier
publist_id: '2980'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Observing structure, function and assembly of single proteins by AFM
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 79
year: '2002'
...
---
_id: '2989'
abstract:
- lang: eng
text: In contrast to animals, little is known about pattern formation in plants.
Physiological and genetic data suggest the involvement of the phytohormone auxin
in this process. Here, we characterize a novel member of the PIN family of putative
auxin efflux carriers, Arabidopsis PIN4, that is localized in developing and mature
root meristems. Atpin4 mutants are defective in establishment and maintenance
of endogenous auxin gradients, fail to canalize externally applied auxin, and
display various patterning defects in both embryonic and seedling roots. We propose
a role for AtPIN4 in generating a sink for auxin below the quiescent center of
the root meristem that is essential for auxin distribution and patterning.
acknowledgement: We thank Petra Tänzler, Michaela Lehnen, and Thomas Steinmann for
technical help. We acknowledge the Arabidopsis Biological Resource Center (Columbus,
OH) and Thomas Altman for providing material. We also gratefully acknowledge the
ADIS service group for DNA sequencing and ZIGIA (Center for Functional Genomics
in Arabidopsis) for the En lines. We are grateful to our colleagues, particularly
Leo Gälweiler, Niko Geldner, Matthias Godde, and Kathrin Schrick for critical reading
of the manuscript. This work was supported by a fellowship of the Deutscher Akademischer
Austauschdienset (J.F.), the Deutsche Forschungsgemeinschaft (Schwerpunktprogramm
Phytohormone), the European Communities Biotechnology Programs, the Fonds der Chemischen
Industrie, and the INCO-Copernicus Program.
article_processing_charge: No
article_type: original
author:
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: Ikram
full_name: Blilou, Ikram
last_name: Blilou
- first_name: Justyna
full_name: Wiśniewska, Justyna
last_name: Wiśniewska
- first_name: Thorsten
full_name: Hamann, Thorsten
last_name: Hamann
- first_name: Karin
full_name: Ljung, Karin
last_name: Ljung
- first_name: Scott
full_name: Woody, Scott
last_name: Woody
- first_name: Göran
full_name: Sandberg, Göran
last_name: Sandberg
- first_name: Ben
full_name: Scheres, Ben
last_name: Scheres
- first_name: Gerd
full_name: Jürgens, Gerd
last_name: Jürgens
- first_name: Klaus
full_name: Palme, Klaus
last_name: Palme
citation:
ama: Friml J, Benková E, Blilou I, et al. AtPIN4 mediates sink-driven auxin gradients
and root patterning in Arabidopsis. Cell. 2002;108(5):661-673. doi:10.1016/S0092-8674(02)00656-6
apa: Friml, J., Benková, E., Blilou, I., Wiśniewska, J., Hamann, T., Ljung, K.,
… Palme, K. (2002). AtPIN4 mediates sink-driven auxin gradients and root patterning
in Arabidopsis. Cell. Cell Press. https://doi.org/10.1016/S0092-8674(02)00656-6
chicago: Friml, Jiří, Eva Benková, Ikram Blilou, Justyna Wiśniewska, Thorsten Hamann,
Karin Ljung, Scott Woody, et al. “AtPIN4 Mediates Sink-Driven Auxin Gradients
and Root Patterning in Arabidopsis.” Cell. Cell Press, 2002. https://doi.org/10.1016/S0092-8674(02)00656-6.
ieee: J. Friml et al., “AtPIN4 mediates sink-driven auxin gradients and root
patterning in Arabidopsis,” Cell, vol. 108, no. 5. Cell Press, pp. 661–673,
2002.
ista: Friml J, Benková E, Blilou I, Wiśniewska J, Hamann T, Ljung K, Woody S, Sandberg
G, Scheres B, Jürgens G, Palme K. 2002. AtPIN4 mediates sink-driven auxin gradients
and root patterning in Arabidopsis. Cell. 108(5), 661–673.
mla: Friml, Jiří, et al. “AtPIN4 Mediates Sink-Driven Auxin Gradients and Root Patterning
in Arabidopsis.” Cell, vol. 108, no. 5, Cell Press, 2002, pp. 661–73, doi:10.1016/S0092-8674(02)00656-6.
short: J. Friml, E. Benková, I. Blilou, J. Wiśniewska, T. Hamann, K. Ljung, S. Woody,
G. Sandberg, B. Scheres, G. Jürgens, K. Palme, Cell 108 (2002) 661–673.
date_created: 2018-12-11T12:00:43Z
date_published: 2002-03-08T00:00:00Z
date_updated: 2023-07-17T11:57:40Z
day: '08'
doi: 10.1016/S0092-8674(02)00656-6
extern: '1'
external_id:
pmid:
- '11893337'
intvolume: ' 108'
issue: '5'
language:
- iso: eng
month: '03'
oa_version: None
page: 661 - 673
pmid: 1
publication: Cell
publication_identifier:
issn:
- 0092-8674
publication_status: published
publisher: Cell Press
publist_id: '3713'
quality_controlled: '1'
scopus_import: '1'
status: public
title: AtPIN4 mediates sink-driven auxin gradients and root patterning in Arabidopsis
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 108
year: '2002'
...
---
_id: '3422'
abstract:
- lang: eng
text: Quantitative real-time PCR represents a highly sensitive and powerful technique
for the quantitation of nucleic acids. It has a tremendous potential for the high-throughput
analysis of gene expression in research and routine diagnostics. However, the
major hurdle is not the practical performance of the experiments themselves but
rather the efficient evaluation and the mathematical and statistical analysis
of the enormous amount of data gained by this technology, as these functions are
not included in the software provided by the manufacturers of the detection systems.
In this work, we focus on the mathematical evaluation and analysis of the data
generated by quantitative real-time PCR, the calculation of the final results,
the propagation of experimental variation of the measured values to the final
results, and the statistical analysis. We developed a Microsoft Excel-based software
application coded in Visual Basic for Applications, called Q-Gene, which addresses
these points. Q-Gene manages and expedites the planning, performance, and evaluation
of quantitative real-time PCR experiments, as well as the mathematical and statistical
analysis, storage, and graphical presentation of the data. The Q-Gene software
application is a tool to cope with complex quantitative real-time PCR experiments
at a high-throughput scale and considerably expedites and rationalizes the experimental
setup, data analysis, and data management while ensuring highest reproducibility.
article_processing_charge: No
article_type: original
author:
- first_name: Patrick
full_name: Müller, Patrick
last_name: Müller
- first_name: Harald L
full_name: Janovjak, Harald L
id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
last_name: Janovjak
orcid: 0000-0002-8023-9315
- first_name: Andre
full_name: Miserez, Andre
last_name: Miserez
- first_name: Zuzana
full_name: Dobbie, Zuzana
last_name: Dobbie
citation:
ama: Müller P, Janovjak HL, Miserez A, Dobbie Z. Processing of gene expression data
generated by quantitative real-time RT-PCR. Biotechniques. 2002;32(6):1372-1379.
apa: Müller, P., Janovjak, H. L., Miserez, A., & Dobbie, Z. (2002). Processing
of gene expression data generated by quantitative real-time RT-PCR. Biotechniques.
Informa Healthcare.
chicago: Müller, Patrick, Harald L Janovjak, Andre Miserez, and Zuzana Dobbie. “Processing
of Gene Expression Data Generated by Quantitative Real-Time RT-PCR.” Biotechniques.
Informa Healthcare, 2002.
ieee: P. Müller, H. L. Janovjak, A. Miserez, and Z. Dobbie, “Processing of gene
expression data generated by quantitative real-time RT-PCR,” Biotechniques,
vol. 32, no. 6. Informa Healthcare, pp. 1372–1379, 2002.
ista: Müller P, Janovjak HL, Miserez A, Dobbie Z. 2002. Processing of gene expression
data generated by quantitative real-time RT-PCR. Biotechniques. 32(6), 1372–1379.
mla: Müller, Patrick, et al. “Processing of Gene Expression Data Generated by Quantitative
Real-Time RT-PCR.” Biotechniques, vol. 32, no. 6, Informa Healthcare, 2002,
pp. 1372–79.
short: P. Müller, H.L. Janovjak, A. Miserez, Z. Dobbie, Biotechniques 32 (2002)
1372–1379.
date_created: 2018-12-11T12:03:15Z
date_published: 2002-06-01T00:00:00Z
date_updated: 2023-07-17T11:29:06Z
day: '01'
extern: '1'
external_id:
pmid:
- '12074169'
intvolume: ' 32'
issue: '6'
language:
- iso: eng
month: '06'
oa_version: None
page: 1372 - 1379
pmid: 1
publication: Biotechniques
publication_identifier:
issn:
- 0736-6205
publication_status: published
publisher: Informa Healthcare
publist_id: '2979'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Processing of gene expression data generated by quantitative real-time RT-PCR
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 32
year: '2002'
...
---
_id: '3140'
abstract:
- lang: eng
text: The maturation of synaptic structures depends on inductive interactions between
axons and their prospective targets. One example of such an interaction is the
influence of proprioceptive sensory axons on the differentiation of muscle spindles.
We have monitored the expression of three transcription factors, Egr3, Pea3, and
Erm, that delineate early muscle spindle development in an assay of muscle spindle-inducing
signals. We provide genetic evidence that Neuregulin1 (Nrg1) is required for proprioceptive
afferent-evoked induction of muscle spindle differentiation in the mouse. Ig-Nrg1
isoforms are preferentially expressed by proprioceptive sensory neurons and are
sufficient to induce muscle spindle differentiation in vivo, whereas CRD-Nrg1
isoforms are broadly expressed in sensory and motor neurons but are not required
for muscle spindle induction.
acknowledgement: We thank L. Role for generously providing the CRD-Nrg1 mutant allele
for these studies, L. Parada and D. Anderson for sharing the TrkC and Ngn1 mouse
strains, W. Tourtellotte for providing Egr3 mutant mice, E. Avetisova for expert
technical assistance, X. Yang for experimental help in the initial phase of these
studies, A. Garratt for advice with ErbB antibodies, and L. Role and G. Fischbach
for helpful discussions. The CRD-Nrg1 mutant allele was generated in the lab of
Dr. Lorna Role, with the support of NIH grant NS29071. S.A. and S.H. were supported
by a grant from the Swiss National Science Foundation and the Kanton of Basel-Stadt.
S.J.B. was supported by grants from the NINDS. N.A.S. was supported by a Howard
Hughes Medical Institute Postdoctoral Fellowship for Physicians and a Career Development
Award from the NINDS. T.M.J. was supported by grants from NINDS and is an Investigator
of the Howard Hughes Medical Institute.
article_processing_charge: No
article_type: original
author:
- first_name: Simon
full_name: Hippenmeyer, Simon
id: 37B36620-F248-11E8-B48F-1D18A9856A87
last_name: Hippenmeyer
orcid: 0000-0003-2279-1061
- first_name: Neil
full_name: Shneider, Neil
last_name: Shneider
- first_name: Carmen
full_name: Birchmeier, Carmen
last_name: Birchmeier
- first_name: Steven
full_name: Burden, Steven
last_name: Burden
- first_name: Thomas
full_name: Jessell, Thomas
last_name: Jessell
- first_name: Silvia
full_name: Arber, Silvia
last_name: Arber
citation:
ama: Hippenmeyer S, Shneider N, Birchmeier C, Burden S, Jessell T, Arber S. A role
for Neuregulin1 signaling in muscle spindle differentiation. Neuron. 2002;36(6):1035-1049.
doi:10.1016/S0896-6273(02)01101-7
apa: Hippenmeyer, S., Shneider, N., Birchmeier, C., Burden, S., Jessell, T., &
Arber, S. (2002). A role for Neuregulin1 signaling in muscle spindle differentiation.
Neuron. Elsevier. https://doi.org/10.1016/S0896-6273(02)01101-7
chicago: Hippenmeyer, Simon, Neil Shneider, Carmen Birchmeier, Steven Burden, Thomas
Jessell, and Silvia Arber. “A Role for Neuregulin1 Signaling in Muscle Spindle
Differentiation.” Neuron. Elsevier, 2002. https://doi.org/10.1016/S0896-6273(02)01101-7.
ieee: S. Hippenmeyer, N. Shneider, C. Birchmeier, S. Burden, T. Jessell, and S.
Arber, “A role for Neuregulin1 signaling in muscle spindle differentiation,” Neuron,
vol. 36, no. 6. Elsevier, pp. 1035–1049, 2002.
ista: Hippenmeyer S, Shneider N, Birchmeier C, Burden S, Jessell T, Arber S. 2002.
A role for Neuregulin1 signaling in muscle spindle differentiation. Neuron. 36(6),
1035–1049.
mla: Hippenmeyer, Simon, et al. “A Role for Neuregulin1 Signaling in Muscle Spindle
Differentiation.” Neuron, vol. 36, no. 6, Elsevier, 2002, pp. 1035–49,
doi:10.1016/S0896-6273(02)01101-7.
short: S. Hippenmeyer, N. Shneider, C. Birchmeier, S. Burden, T. Jessell, S. Arber,
Neuron 36 (2002) 1035–1049.
date_created: 2018-12-11T12:01:37Z
date_published: 2002-12-19T00:00:00Z
date_updated: 2023-07-17T11:46:43Z
day: '19'
doi: 10.1016/S0896-6273(02)01101-7
extern: '1'
external_id:
pmid:
- '12495620'
intvolume: ' 36'
issue: '6'
language:
- iso: eng
month: '12'
oa_version: None
page: 1035 - 1049
pmid: 1
publication: Neuron
publication_identifier:
issn:
- 0896-6273
publication_status: published
publisher: Elsevier
publist_id: '3558'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A role for Neuregulin1 signaling in muscle spindle differentiation
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 36
year: '2002'
...
---
_id: '3423'
article_processing_charge: No
author:
- first_name: Wolfgang
full_name: Bauer, Wolfgang
last_name: Bauer
- first_name: Mark Tobias
full_name: Bollenbach, Mark Tobias
id: 3E6DB97A-F248-11E8-B48F-1D18A9856A87
last_name: Bollenbach
orcid: 0000-0003-4398-476X
- first_name: Marko
full_name: Kleine Berkenbusch, Marko
last_name: Kleine Berkenbusch
- first_name: Holger
full_name: Harreis, Holger
last_name: Harreis
citation:
ama: 'Bauer W, Bollenbach MT, Kleine Berkenbusch M, Harreis H. The percolation interpretation
of the nuclear fragmentation phase transition. In: Proceedings of the 18th
Winter Workshop on Nuclear Dynamics. EP Systema; 2002:111-118.'
apa: 'Bauer, W., Bollenbach, M. T., Kleine Berkenbusch, M., & Harreis, H. (2002).
The percolation interpretation of the nuclear fragmentation phase transition.
In Proceedings of the 18th Winter Workshop on Nuclear Dynamics (pp. 111–118).
Nassau, Bahamas: EP Systema.'
chicago: Bauer, Wolfgang, Mark Tobias Bollenbach, Marko Kleine Berkenbusch, and
Holger Harreis. “The Percolation Interpretation of the Nuclear Fragmentation Phase
Transition.” In Proceedings of the 18th Winter Workshop on Nuclear Dynamics,
111–18. EP Systema, 2002.
ieee: W. Bauer, M. T. Bollenbach, M. Kleine Berkenbusch, and H. Harreis, “The percolation
interpretation of the nuclear fragmentation phase transition,” in Proceedings
of the 18th Winter Workshop on Nuclear Dynamics, Nassau, Bahamas, 2002, pp.
111–118.
ista: Bauer W, Bollenbach MT, Kleine Berkenbusch M, Harreis H. 2002. The percolation
interpretation of the nuclear fragmentation phase transition. Proceedings of the
18th Winter Workshop on Nuclear Dynamics. Winter Workshop on Nuclear Dynamics,
111–118.
mla: Bauer, Wolfgang, et al. “The Percolation Interpretation of the Nuclear Fragmentation
Phase Transition.” Proceedings of the 18th Winter Workshop on Nuclear Dynamics,
EP Systema, 2002, pp. 111–18.
short: W. Bauer, M.T. Bollenbach, M. Kleine Berkenbusch, H. Harreis, in:, Proceedings
of the 18th Winter Workshop on Nuclear Dynamics, EP Systema, 2002, pp. 111–118.
conference:
end_date: 2002-01-22
location: Nassau, Bahamas
name: Winter Workshop on Nuclear Dynamics
start_date: 2002-01-20
date_created: 2018-12-11T12:03:15Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-07-17T11:15:14Z
day: '01'
extern: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 111 - 118
publication: Proceedings of the 18th Winter Workshop on Nuclear Dynamics
publication_status: published
publisher: EP Systema
publist_id: '2978'
status: public
title: The percolation interpretation of the nuclear fragmentation phase transition
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '2002'
...
---
_id: '2986'
abstract:
- lang: eng
text: Long-standing models propose that plant growth responses to light or gravity
are mediated by asymmetric distribution of the phytohormone auxin. Physiological
studies implicated a specific transport system that relocates auxin laterally,
thereby effecting differential growth; however, neither the molecular components
of this system nor the cellular mechanism of auxin redistribution on light or
gravity perception have been identified. Here, we show that auxin accumulates
asymmetrically during differential growth in an efflux-dependent manner. Mutations
in the Arabidopsis gene PIN3, a regulator of auxin efflux, alter differential
growth. PIN3 is expressed in gravity-sensing tissues, with PIN3 protein accumulating
predominantly at the lateral cell surface. PIN3 localizes to the plasma membrane
and to vesicles that cycle in an actin-dependent manner. In the root columella,
PIN3 is positioned symmetrically at the plasma membrane but rapidly relocalizes
laterally on gravity stimulation. Our data indicate that PIN3 is a component of
the lateral auxin transport system regulating tropic growth. In addition, actin-dependent
relocalization of PIN3 in response to gravity provides a mechanism for redirecting
auxin flux to trigger asymmetric growth.
acknowledgement: We thank G. Jürgens for enabling J.F. to accomplish part of this
work in his laboratory; P. Tänzler and M. Sauer for technical assistance; H. Vahlenkamp
for technical assistance in immunocytochemistry; M. Estelle for providing material
and suggestions; T. Altman for BAC filter sets; the ADIS (Automated DNA Isolation
and Sequencing) service group for DNA sequencing; ZIGIA (Center for Functional Genomics
in Arabidopsis) for the En lines; and N. Geldner, T. Hamann, G. Jürgens, K. Schrick
and C. Schwechheimer for comments and critical reading of the manuscript. This work
was supported by a fellowship of the DAAD (J.F.), the DFG (Schwerpunktprogramm Phytohormone),
the Fonds der chemischen Industrie, the European Communities Biotechnology Programs,
the INCO-Copernicus Program and the European Space Agency MAP-Biotechnology Programme
article_processing_charge: No
article_type: original
author:
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Justyna
full_name: Wiśniewska, Justyna
last_name: Wiśniewska
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: Kurt
full_name: Mendgen, Kurt
last_name: Mendgen
- first_name: Klaus
full_name: Palme, Klaus
last_name: Palme
citation:
ama: Friml J, Wiśniewska J, Benková E, Mendgen K, Palme K. Lateral relocation of
auxin efflux regulator PIN3 mediates tropism in Arabidopsis. Nature. 2002;415(6873):806-809.
doi:10.1038/415806a
apa: Friml, J., Wiśniewska, J., Benková, E., Mendgen, K., & Palme, K. (2002).
Lateral relocation of auxin efflux regulator PIN3 mediates tropism in Arabidopsis.
Nature. Nature Publishing Group. https://doi.org/10.1038/415806a
chicago: Friml, Jiří, Justyna Wiśniewska, Eva Benková, Kurt Mendgen, and Klaus Palme.
“Lateral Relocation of Auxin Efflux Regulator PIN3 Mediates Tropism in Arabidopsis.”
Nature. Nature Publishing Group, 2002. https://doi.org/10.1038/415806a.
ieee: J. Friml, J. Wiśniewska, E. Benková, K. Mendgen, and K. Palme, “Lateral relocation
of auxin efflux regulator PIN3 mediates tropism in Arabidopsis,” Nature,
vol. 415, no. 6873. Nature Publishing Group, pp. 806–809, 2002.
ista: Friml J, Wiśniewska J, Benková E, Mendgen K, Palme K. 2002. Lateral relocation
of auxin efflux regulator PIN3 mediates tropism in Arabidopsis. Nature. 415(6873),
806–809.
mla: Friml, Jiří, et al. “Lateral Relocation of Auxin Efflux Regulator PIN3 Mediates
Tropism in Arabidopsis.” Nature, vol. 415, no. 6873, Nature Publishing
Group, 2002, pp. 806–09, doi:10.1038/415806a.
short: J. Friml, J. Wiśniewska, E. Benková, K. Mendgen, K. Palme, Nature 415 (2002)
806–809.
date_created: 2018-12-11T12:00:42Z
date_published: 2002-02-14T00:00:00Z
date_updated: 2023-07-18T07:30:27Z
day: '14'
doi: 10.1038/415806a
extern: '1'
external_id:
pmid:
- '11845211 '
intvolume: ' 415'
issue: '6873'
language:
- iso: eng
month: '02'
oa_version: None
page: 806 - 809
pmid: 1
publication: Nature
publication_identifier:
issn:
- 0028-0836
publication_status: published
publisher: Nature Publishing Group
publist_id: '3715'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Lateral relocation of auxin efflux regulator PIN3 mediates tropism in Arabidopsis
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 415
year: '2002'
...
---
_id: '2987'
abstract:
- lang: eng
text: The hydra mutants of Arabidopsis are characterized by a pleiotropic phenotype
that shows defective embryonic and seedling cell patterning, morphogenesis, and
root growth. We demonstrate that the HYDRA1 gene encodes a Δ8-Δ7 sterol isomerase,
whereas HYDRA2 encodes a sterol C14 reductase, previously identified as the FACKEL
gene product. Seedlings mutant for each gene are similarly defective in the concentrations
of the three major Arabidopsis sterols. Promoter::reporter gene analysis showed
misexpression of the auxin-regulated DR5 and ACS1 promoters and of the epidermal
cell file-specific GL2 promoter in the mutants. The mutants exhibit enhanced responses
to auxin. The phenotypes can be rescued partially by inhibition of auxin and ethylene
signaling but not by exogenous sterols or brassinosteroids. We propose a model
in which correct sterol profiles are required for regulated auxin and ethylene
signaling through effects on membrane function.
acknowledgement: We thank Dr. Ken Feldmann for providing prospective hyd alleles,
Dr. Jane Murfett for providing DR5::GUS seed, Dr. D. Van Der Straeten for providing
ACS1::GUS seed, Dr. John Schiefelbein for providing GL2::GFP seed, and Dr. Ottoline
Leyser for axr1-12 and axr3-1 seed. etr1 and fk seed was obtained from the Nottingham
Arabidopsis Stock Centre. This work was supported by a Biotechnology and Biological
Science Research Council research studentship to M.S., a Durham University studentship
to M.P., and Biotechnology and Biological Science Research Council Grant 12/P02330
to J.T.
article_processing_charge: No
article_type: original
author:
- first_name: Martin
full_name: Souter, Martin
last_name: Souter
- first_name: Jennifer
full_name: Topping, Jennifer
last_name: Topping
- first_name: Margaret
full_name: Pullen, Margaret
last_name: Pullen
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Klaus
full_name: Palme, Klaus
last_name: Palme
- first_name: Rachel
full_name: Hackett, Rachel
last_name: Hackett
- first_name: Don
full_name: Grierson, Don
last_name: Grierson
- first_name: Keith
full_name: Lindsey, Keith
last_name: Lindsey
citation:
ama: Souter M, Topping J, Pullen M, et al. Hydra mutants of Arabidopsis are defective
in sterol profiles and auxin and ethylene signaling. Plant Cell. 2002;14(5):1017-1031.
doi:10.1105/tpc.001248
apa: Souter, M., Topping, J., Pullen, M., Friml, J., Palme, K., Hackett, R., … Lindsey,
K. (2002). Hydra mutants of Arabidopsis are defective in sterol profiles and auxin
and ethylene signaling. Plant Cell. American Society of Plant Biologists.
https://doi.org/10.1105/tpc.001248
chicago: Souter, Martin, Jennifer Topping, Margaret Pullen, Jiří Friml, Klaus Palme,
Rachel Hackett, Don Grierson, and Keith Lindsey. “Hydra Mutants of Arabidopsis
Are Defective in Sterol Profiles and Auxin and Ethylene Signaling.” Plant Cell.
American Society of Plant Biologists, 2002. https://doi.org/10.1105/tpc.001248.
ieee: M. Souter et al., “Hydra mutants of Arabidopsis are defective in sterol
profiles and auxin and ethylene signaling,” Plant Cell, vol. 14, no. 5.
American Society of Plant Biologists, pp. 1017–1031, 2002.
ista: Souter M, Topping J, Pullen M, Friml J, Palme K, Hackett R, Grierson D, Lindsey
K. 2002. Hydra mutants of Arabidopsis are defective in sterol profiles and auxin
and ethylene signaling. Plant Cell. 14(5), 1017–1031.
mla: Souter, Martin, et al. “Hydra Mutants of Arabidopsis Are Defective in Sterol
Profiles and Auxin and Ethylene Signaling.” Plant Cell, vol. 14, no. 5,
American Society of Plant Biologists, 2002, pp. 1017–31, doi:10.1105/tpc.001248.
short: M. Souter, J. Topping, M. Pullen, J. Friml, K. Palme, R. Hackett, D. Grierson,
K. Lindsey, Plant Cell 14 (2002) 1017–1031.
date_created: 2018-12-11T12:00:42Z
date_published: 2002-05-01T00:00:00Z
date_updated: 2023-07-18T07:34:32Z
day: '01'
doi: 10.1105/tpc.001248
extern: '1'
external_id:
pmid:
- '12034894'
intvolume: ' 14'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC150604/
month: '05'
oa: 1
oa_version: None
page: 1017 - 1031
pmid: 1
publication: Plant Cell
publication_identifier:
issn:
- 1040-4651
publication_status: published
publisher: American Society of Plant Biologists
publist_id: '3716'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Hydra mutants of Arabidopsis are defective in sterol profiles and auxin and
ethylene signaling
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 14
year: '2002'
...
---
_id: '2866'
abstract:
- lang: eng
text: 'Developmental responses to the plant hormone auxin are thought to be mediated
by interacting pairs from two protein families: short-lived inhibitory IAA proteins
and ARF transcription factors binding to auxin-response elements. Monopteros mutants
lacking activating ARF5 and the auxin-insensitive mutant bodenlos fail to initiate
the root meristem during early embryogenesis. Here we show that the bodenlos phenotype
results from an amino-acid exchange in the conserved degradation domain of IAA12.
BODENLOS and MONOPTEROS interact in the yeast two-hybrid assay and the two genes
are coexpressed in early embryogenesis, suggesting that BODENLOS inhibits MONOPTEROS
action in root meristem initiation.'
acknowledgement: "We thank C. Maulbetsch for isolating BDL cDNA clones; T. Berleth
and J. Friml for providing clones for in situ probes; K. Harter for making available
the parsley protoplast system; and J. Friml, N. Geldner, M. Griffith, C. Schwechheimer,
D. Weigel, and D. Weijers for helpful comments and critical reading of the manuscript.
This work was supported by Sonderforschungsbereich 446 “Mechanismen des Zellverhaltens
bei Eukaryoten.”\r\n\r\nThe publication costs of this article were defrayed in part
by payment of page charges. This article must therefore be hereby marked “advertisement”
in accordance with 18 USC section 1734 solely to indicate this fact."
article_processing_charge: No
article_type: original
author:
- first_name: Thorsten
full_name: Hamann, Thorsten
last_name: Hamann
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
- first_name: Isabel
full_name: Bäurle, Isabel
last_name: Bäurle
- first_name: Marika
full_name: Kientz, Marika
last_name: Kientz
- first_name: Gerd
full_name: Jürgens, Gerd
last_name: Jürgens
citation:
ama: Hamann T, Benková E, Bäurle I, Kientz M, Jürgens G. The Arabidopsis BODENLOS
gene encodes an auxin response protein inhibiting MONOPTEROS-mediated embryo patterning.
Genes and Development. 2002;16(13):1610-1615. doi:10.1101/gad.229402
apa: Hamann, T., Benková, E., Bäurle, I., Kientz, M., & Jürgens, G. (2002).
The Arabidopsis BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated
embryo patterning. Genes and Development. Cold Spring Harbor Laboratory
Press. https://doi.org/10.1101/gad.229402
chicago: Hamann, Thorsten, Eva Benková, Isabel Bäurle, Marika Kientz, and Gerd Jürgens.
“The Arabidopsis BODENLOS Gene Encodes an Auxin Response Protein Inhibiting MONOPTEROS-Mediated
Embryo Patterning.” Genes and Development. Cold Spring Harbor Laboratory
Press, 2002. https://doi.org/10.1101/gad.229402.
ieee: T. Hamann, E. Benková, I. Bäurle, M. Kientz, and G. Jürgens, “The Arabidopsis
BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated
embryo patterning,” Genes and Development, vol. 16, no. 13. Cold Spring
Harbor Laboratory Press, pp. 1610–1615, 2002.
ista: Hamann T, Benková E, Bäurle I, Kientz M, Jürgens G. 2002. The Arabidopsis
BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated
embryo patterning. Genes and Development. 16(13), 1610–1615.
mla: Hamann, Thorsten, et al. “The Arabidopsis BODENLOS Gene Encodes an Auxin Response
Protein Inhibiting MONOPTEROS-Mediated Embryo Patterning.” Genes and Development,
vol. 16, no. 13, Cold Spring Harbor Laboratory Press, 2002, pp. 1610–15, doi:10.1101/gad.229402.
short: T. Hamann, E. Benková, I. Bäurle, M. Kientz, G. Jürgens, Genes and Development
16 (2002) 1610–1615.
date_created: 2018-12-11T12:00:01Z
date_published: 2002-07-01T00:00:00Z
date_updated: 2023-07-18T08:26:58Z
day: '01'
doi: 10.1101/gad.229402
extern: '1'
external_id:
pmid:
- '12101120'
intvolume: ' 16'
issue: '13'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC186366/
month: '07'
oa: 1
oa_version: Published Version
page: 1610 - 1615
pmid: 1
publication: Genes and Development
publication_identifier:
issn:
- 0890-9369
publication_status: published
publisher: Cold Spring Harbor Laboratory Press
publist_id: '3921'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The Arabidopsis BODENLOS gene encodes an auxin response protein inhibiting
MONOPTEROS-mediated embryo patterning
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 16
year: '2002'
...
---
_id: '2927'
abstract:
- lang: eng
text: 'In the last few years, several new algorithms based on graph cuts have been
developed to solve energy minimization problems in computer vision. Each of these
techniques constructs a graph such that the minimum cut on the graph also minimizes
the energy. Yet because these graph constructions are complex and highly specific
to a particular energy function, graph cuts have seen limited application to date.
In this paper we characterize the energy functions that can be minimized by graph
cuts. Our results are restricted to energy functions with binary variables. However,
our work generalizes many previous constructions, and is easily applicable to
vision problems that involve large numbers of labels, such as stereo, motion,
image restoration and scene reconstruction. We present three main results: a necessary
condition for any energy function that can be minimized by graph cuts; a sufficient
condition for energy functions that can be written as a sum of functions of up
to three variables at a time; and a general-purpose construction to minimize such
an energy function. Researchers who are considering the use of graph cuts to optimize
a particular energy function can use our results to determine if this is possible,
and then follow our construction to create the appropriate graph.'
acknowledgement: We thank Olga Veksler and Yuri Boykov for their careful reading of
this paper, and for valuable comments which greatly improved itsreadibility. We
also thank Ian Jermyn for helping us clarify the paper’s motivation. This research
was supported by NSF grants IIS-9900115 and CCR-0113371, and by a grant from Microsoft
Research.
article_processing_charge: No
author:
- first_name: Vladimir
full_name: Kolmogorov, Vladimir
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
- first_name: Ramin
full_name: Zabih, Ramin
last_name: Zabih
citation:
ama: 'Kolmogorov V, Zabih R. Multi-camera scene reconstruction via graph cuts. In:
Proceedings of the 7th European Conference on Computer Vision. Springer;
2002:65-81. doi:10.1007/3-540-47977-5_5'
apa: 'Kolmogorov, V., & Zabih, R. (2002). Multi-camera scene reconstruction
via graph cuts. In Proceedings of the 7th European Conference on Computer Vision
(pp. 65–81). Copenhagen, Denmark: Springer. https://doi.org/10.1007/3-540-47977-5_5'
chicago: Kolmogorov, Vladimir, and Ramin Zabih. “Multi-Camera Scene Reconstruction
via Graph Cuts.” In Proceedings of the 7th European Conference on Computer
Vision, 65–81. Springer, 2002. https://doi.org/10.1007/3-540-47977-5_5.
ieee: V. Kolmogorov and R. Zabih, “Multi-camera scene reconstruction via graph cuts,”
in Proceedings of the 7th European Conference on Computer Vision, Copenhagen,
Denmark, 2002, pp. 65–81.
ista: 'Kolmogorov V, Zabih R. 2002. Multi-camera scene reconstruction via graph
cuts. Proceedings of the 7th European Conference on Computer Vision. ECCV: European
Conference on Computer Vision, 65–81.'
mla: Kolmogorov, Vladimir, and Ramin Zabih. “Multi-Camera Scene Reconstruction via
Graph Cuts.” Proceedings of the 7th European Conference on Computer Vision,
Springer, 2002, pp. 65–81, doi:10.1007/3-540-47977-5_5.
short: V. Kolmogorov, R. Zabih, in:, Proceedings of the 7th European Conference
on Computer Vision, Springer, 2002, pp. 65–81.
conference:
end_date: 2002-05-31
location: Copenhagen, Denmark
name: 'ECCV: European Conference on Computer Vision'
start_date: 2002-05-28
date_created: 2018-12-11T12:00:23Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-07-18T08:20:02Z
day: '01'
doi: 10.1007/3-540-47977-5_5
extern: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 65 - 81
publication: Proceedings of the 7th European Conference on Computer Vision
publication_identifier:
isbn:
- '9783540437468'
publication_status: published
publisher: Springer
publist_id: '3810'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Multi-camera scene reconstruction via graph cuts
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '2002'
...
---
_id: '2739'
abstract:
- lang: eng
text: We define the two dimensional Pauli operator and identify its core for magnetic
fields that are regular Borel measures. The magnetic field is generated by a scalar
potential hence we bypass the usual A L 2loc condition on the vector potential,
which does not allow to consider such singular fields. We extend the Aharonov-Casher
theorem for magnetic fields that are measures with finite total variation and
we present a counterexample in case of infinite total variation. One of the key
technical tools is a weighted L 2 estimate on a singular integral operator.
acknowledgement: "This work started during the first author’s visit at the Erwin Schrödinger
Institute, Vienna.\r\nValuable discussions with T. Hoffmann-Ostenhof and M. Loss
are gratefully acknowledged. The authors thank\r\nthe referee for careful reading
and comments"
article_processing_charge: No
article_type: original
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Vitali
full_name: Vougalter, Vitali
last_name: Vougalter
citation:
ama: Erdös L, Vougalter V. Pauli operator and Aharonov–Casher theorem¶ for measure
valued magnetic fields. Communications in Mathematical Physics. 2002;225(2):399-421.
doi:10.1007/s002200100585
apa: Erdös, L., & Vougalter, V. (2002). Pauli operator and Aharonov–Casher theorem¶
for measure valued magnetic fields. Communications in Mathematical Physics.
Springer. https://doi.org/10.1007/s002200100585
chicago: Erdös, László, and Vitali Vougalter. “Pauli Operator and Aharonov–Casher
Theorem¶ for Measure Valued Magnetic Fields.” Communications in Mathematical
Physics. Springer, 2002. https://doi.org/10.1007/s002200100585.
ieee: L. Erdös and V. Vougalter, “Pauli operator and Aharonov–Casher theorem¶ for
measure valued magnetic fields,” Communications in Mathematical Physics,
vol. 225, no. 2. Springer, pp. 399–421, 2002.
ista: Erdös L, Vougalter V. 2002. Pauli operator and Aharonov–Casher theorem¶ for
measure valued magnetic fields. Communications in Mathematical Physics. 225(2),
399–421.
mla: Erdös, László, and Vitali Vougalter. “Pauli Operator and Aharonov–Casher Theorem¶
for Measure Valued Magnetic Fields.” Communications in Mathematical Physics,
vol. 225, no. 2, Springer, 2002, pp. 399–421, doi:10.1007/s002200100585.
short: L. Erdös, V. Vougalter, Communications in Mathematical Physics 225 (2002)
399–421.
date_created: 2018-12-11T11:59:21Z
date_published: 2002-02-01T00:00:00Z
date_updated: 2023-07-18T08:57:54Z
day: '01'
doi: 10.1007/s002200100585
extern: '1'
external_id:
arxiv:
- math-ph/0109015v1
intvolume: ' 225'
issue: '2'
language:
- iso: eng
month: '02'
oa_version: None
page: 399 - 421
publication: Communications in Mathematical Physics
publication_identifier:
issn:
- 0010-3616
publication_status: published
publisher: Springer
publist_id: '4153'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Pauli operator and Aharonov–Casher theorem¶ for measure valued magnetic fields
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 225
year: '2002'
...
---
_id: '2738'
abstract:
- lang: eng
text: We consider the long time evolution of a quantum particle weakly interacting
with a phonon field. We show that in the weak coupling limit the Wigner distribution
of the electron density matrix converges to the solution of the linear Boltzmann
equation globally in time. The collision kernel is identified as the sum of an
emission and an absorption term that depend on the equilibrium distribution of
the free phonon modes.
acknowledgement: "This work initially was a joint project with H.-T. Yau and several
ideas\r\npresented here have been developed in collaboration with him. I would like\r\nto
thank him for the invaluable discussions and encouragement through\r\nthe entire
work. Part of this project was completed during several visits at\r\nthe Erwin Schrödinger
Institute, Vienna, and at the Center of Theoretical\r\nStudies, Hsinchu, Taiwan.
The author is grateful for the hospitality and\r\nfinancial support. This work was
partially supported by NSF Grant DMS9970323."
article_processing_charge: No
article_type: original
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
citation:
ama: Erdös L. Linear Boltzmann equation as the long time dynamics of an electron
weakly coupled to a phonon field. Journal of Statistical Physics. 2002;107(5-6):1043-1127.
doi:10.1023/A:1015157624384
apa: Erdös, L. (2002). Linear Boltzmann equation as the long time dynamics of an
electron weakly coupled to a phonon field. Journal of Statistical Physics.
Springer. https://doi.org/10.1023/A:1015157624384
chicago: Erdös, László. “Linear Boltzmann Equation as the Long Time Dynamics of
an Electron Weakly Coupled to a Phonon Field.” Journal of Statistical Physics.
Springer, 2002. https://doi.org/10.1023/A:1015157624384.
ieee: L. Erdös, “Linear Boltzmann equation as the long time dynamics of an electron
weakly coupled to a phonon field,” Journal of Statistical Physics, vol.
107, no. 5–6. Springer, pp. 1043–1127, 2002.
ista: Erdös L. 2002. Linear Boltzmann equation as the long time dynamics of an electron
weakly coupled to a phonon field. Journal of Statistical Physics. 107(5–6), 1043–1127.
mla: Erdös, László. “Linear Boltzmann Equation as the Long Time Dynamics of an Electron
Weakly Coupled to a Phonon Field.” Journal of Statistical Physics, vol.
107, no. 5–6, Springer, 2002, pp. 1043–127, doi:10.1023/A:1015157624384.
short: L. Erdös, Journal of Statistical Physics 107 (2002) 1043–1127.
date_created: 2018-12-11T11:59:20Z
date_published: 2002-06-01T00:00:00Z
date_updated: 2023-07-18T09:08:45Z
day: '01'
doi: 10.1023/A:1015157624384
extern: '1'
external_id:
arxiv:
- math-ph/0108025
intvolume: ' 107'
issue: 5-6
language:
- iso: eng
month: '06'
oa_version: Submitted Version
page: 1043 - 1127
publication: Journal of Statistical Physics
publication_identifier:
issn:
- 0022-4715
publication_status: published
publisher: Springer
publist_id: '4154'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Linear Boltzmann equation as the long time dynamics of an electron weakly coupled
to a phonon field
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 107
year: '2002'
...
---
_id: '2740'
abstract:
- lang: eng
text: We show that the lowest eigenvalue of the magnetic Schrödinger operator on
a line bundle over a compact Riemann surface M is bounded by the L1-norm of the
magnetic field B. This implies a similar bound on the multiplicity of the ground
state. An example shows that this degeneracy can indeed be comparable with ∫M
|B| even in case of the trivial bundle.
article_processing_charge: No
article_type: original
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
citation:
ama: Erdös L. Spectral shift and multiplicity of the first eigenvalue of the magnetic
Schrödinger operator in two dimensions. Annales de l’Institut Fourier.
2002;52(6):1833-1874. doi:10.5802/aif.1936
apa: Erdös, L. (2002). Spectral shift and multiplicity of the first eigenvalue of
the magnetic Schrödinger operator in two dimensions. Annales de l’Institut
Fourier. Association des Annales de l’Institut Fourier. https://doi.org/10.5802/aif.1936
chicago: Erdös, László. “Spectral Shift and Multiplicity of the First Eigenvalue
of the Magnetic Schrödinger Operator in Two Dimensions.” Annales de l’Institut
Fourier. Association des Annales de l’Institut Fourier, 2002. https://doi.org/10.5802/aif.1936.
ieee: L. Erdös, “Spectral shift and multiplicity of the first eigenvalue of the
magnetic Schrödinger operator in two dimensions,” Annales de l’Institut Fourier,
vol. 52, no. 6. Association des Annales de l’Institut Fourier, pp. 1833–1874,
2002.
ista: Erdös L. 2002. Spectral shift and multiplicity of the first eigenvalue of
the magnetic Schrödinger operator in two dimensions. Annales de l’Institut Fourier.
52(6), 1833–1874.
mla: Erdös, László. “Spectral Shift and Multiplicity of the First Eigenvalue of
the Magnetic Schrödinger Operator in Two Dimensions.” Annales de l’Institut
Fourier, vol. 52, no. 6, Association des Annales de l’Institut Fourier, 2002,
pp. 1833–74, doi:10.5802/aif.1936.
short: L. Erdös, Annales de l’Institut Fourier 52 (2002) 1833–1874.
date_created: 2018-12-11T11:59:21Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-07-18T08:38:34Z
day: '01'
doi: 10.5802/aif.1936
extern: '1'
intvolume: ' 52'
issue: '6'
language:
- iso: eng
month: '01'
oa_version: None
page: 1833-1874
publication: Annales de l'Institut Fourier
publication_identifier:
issn:
- 0373-0956
publication_status: published
publisher: Association des Annales de l'Institut Fourier
publist_id: '4152'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Spectral shift and multiplicity of the first eigenvalue of the magnetic Schrödinger
operator in two dimensions
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 52
year: '2002'
...
---
_id: '2737'
abstract:
- lang: eng
text: We derive the time-dependent Schrödinger–Poisson equation as the weak coupling
limit of the N-body linear Schrödinger equation with Coulomb potential.
acknowledgement: "The authors thank the ESI in Vienna and the Austrian START project
“Nonlinear Schrödinger\r\nand quantum Boltzmann equations” of N.J.M. for hospitality
and support. Also, F.G. was supported by the Institut\r\nUniversitaire de France
and N.J.M. by the bilateral Austrian-French “AMADEUS” programme. H.-T.Y. and L.E.
were\r\nsupported by NSF Grants DMS-0072098 and DMS-9970323, respectively"
article_processing_charge: No
article_type: original
author:
- first_name: Claude
full_name: Bardos, Claude
last_name: Bardos
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: François
full_name: Golse, François
last_name: Golse
- first_name: Norbert
full_name: Mauser, Norbert
last_name: Mauser
- first_name: Horng
full_name: Yau, Horng
last_name: Yau
citation:
ama: Bardos C, Erdös L, Golse F, Mauser N, Yau H. Derivation of the Schrödinger-Poisson
equation from the quantum N-body problem. Comptes Rendus Mathematique.
2002;334(6):515-520. doi:10.1016/S1631-073X(02)02253-7
apa: Bardos, C., Erdös, L., Golse, F., Mauser, N., & Yau, H. (2002). Derivation
of the Schrödinger-Poisson equation from the quantum N-body problem. Comptes
Rendus Mathematique. Elsevier. https://doi.org/10.1016/S1631-073X(02)02253-7
chicago: Bardos, Claude, László Erdös, François Golse, Norbert Mauser, and Horng
Yau. “Derivation of the Schrödinger-Poisson Equation from the Quantum N-Body Problem.”
Comptes Rendus Mathematique. Elsevier, 2002. https://doi.org/10.1016/S1631-073X(02)02253-7.
ieee: C. Bardos, L. Erdös, F. Golse, N. Mauser, and H. Yau, “Derivation of the Schrödinger-Poisson
equation from the quantum N-body problem,” Comptes Rendus Mathematique,
vol. 334, no. 6. Elsevier, pp. 515–520, 2002.
ista: Bardos C, Erdös L, Golse F, Mauser N, Yau H. 2002. Derivation of the Schrödinger-Poisson
equation from the quantum N-body problem. Comptes Rendus Mathematique. 334(6),
515–520.
mla: Bardos, Claude, et al. “Derivation of the Schrödinger-Poisson Equation from
the Quantum N-Body Problem.” Comptes Rendus Mathematique, vol. 334, no.
6, Elsevier, 2002, pp. 515–20, doi:10.1016/S1631-073X(02)02253-7.
short: C. Bardos, L. Erdös, F. Golse, N. Mauser, H. Yau, Comptes Rendus Mathematique
334 (2002) 515–520.
date_created: 2018-12-11T11:59:20Z
date_published: 2002-03-30T00:00:00Z
date_updated: 2023-07-18T09:24:24Z
day: '30'
doi: 10.1016/S1631-073X(02)02253-7
extern: '1'
intvolume: ' 334'
issue: '6'
language:
- iso: eng
month: '03'
oa_version: None
page: 515 - 520
publication: Comptes Rendus Mathematique
publication_identifier:
issn:
- 1631-073X
publication_status: published
publisher: Elsevier
publist_id: '4155'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Derivation of the Schrödinger-Poisson equation from the quantum N-body problem
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 334
year: '2002'
...
---
_id: '2624'
abstract:
- lang: eng
text: Metabotropic γ-aminobutyric acid receptors (GABABRs) are involved in modulation
of synaptic transmission and activity of cerebellar and thalamic neurons. We used
subtype-specific antibodies in pre- and postembedding immunohistochemistry combined
with three-dimensional reconstruction of labelled profiles and quantification
of immunoparticles to reveal the subcellular distribution of pre- and postsynaptic
GABABR1a/b and GABABR2 in the rat cerebellum and ventrobasal thalamus. GABABR1a/b
and R2 were extensively colocalized in most brain regions including the cerebellum
and thalamus. In the cerebellum, immunoreactivity for both subtypes was prevalent
in the molecular layer. The most intense immunoreactivity was found in Purkinje
cell spines with a high density of immunoparticles at extrasynaptic sites peaking
at around 240 nm from glutamatergic synapses between spines and parallel fibre
varicosities. This is in contrast to dendrites at sites around GABAergic synapses
where sparse and random distribution was found for both subtypes. In addition,
more than one-tenth of the synaptic membrane specialization of spine-parallel
fibre synapses were labelled at pre- or postsynaptic sites. Weak immunolabelling
for both subtypes was also seen in parallel fibres but only rarely in GABAergic
axons. In the ventrobasal thalamus, immunolabelling for both receptor subtypes
was intense over the dendritic field of thalamocortical cells. Electron microscopy
demonstrated an extrasynaptic localization of GABABR1a/b and R2 exclusively in
postsynaptic elements. Quantitative analysis further revealed the density of GABABR1a/b
around GABAergic synapses was higher than glutamatergic synapses on thalamocortical
cell dendrites. The distinct localization of GABABRs relative to synaptic sites
in the cerebellum and ventrobasal thalamus suggests that GABABRs differentially
regulate activity of different neuronal populations.
acknowledgement: This work was supported by research grants from the Ministry of Education,
Science, Sports and Culture of Japan, and the Japan Society for the Promotion of
Science (P96319). We thank Drs L. Zaborszky and R. Luján for their comments on the
manuscript, Dr M. Watanabe for kindly supplying us with GluRδ2 and AMPA GluR1 antibodies,
Dr R.E. Edwards for rabbit BNPI antibody, and J. Hatakeyama and S. Doi for technical
assistance.
article_processing_charge: No
article_type: original
author:
- first_name: Ákos
full_name: Kulik, Ákos
last_name: Kulik
- first_name: Kazuhiko
full_name: Nakadate, Kazuhiko
last_name: Nakadate
- first_name: Gábor
full_name: Nyíri, Gábor
last_name: Nyíri
- first_name: Takuya
full_name: Notomi, Takuya
last_name: Notomi
- first_name: Barbara
full_name: Malitschek, Barbara
last_name: Malitschek
- first_name: Bernhard
full_name: Bettler, Bernhard
last_name: Bettler
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
citation:
ama: Kulik Á, Nakadate K, Nyíri G, et al. Distinct localization of GABAB receptors
relative to synaptic sites in the rat cerebellum and ventrobasal thalamus. European
Journal of Neuroscience. 2002;15(2):291-307. doi:10.1046/j.0953-816x.2001.01855.x
apa: Kulik, Á., Nakadate, K., Nyíri, G., Notomi, T., Malitschek, B., Bettler, B.,
& Shigemoto, R. (2002). Distinct localization of GABAB receptors relative
to synaptic sites in the rat cerebellum and ventrobasal thalamus. European
Journal of Neuroscience. Wiley-Blackwell. https://doi.org/10.1046/j.0953-816x.2001.01855.x
chicago: Kulik, Ákos, Kazuhiko Nakadate, Gábor Nyíri, Takuya Notomi, Barbara Malitschek,
Bernhard Bettler, and Ryuichi Shigemoto. “Distinct Localization of GABAB Receptors
Relative to Synaptic Sites in the Rat Cerebellum and Ventrobasal Thalamus.” European
Journal of Neuroscience. Wiley-Blackwell, 2002. https://doi.org/10.1046/j.0953-816x.2001.01855.x.
ieee: Á. Kulik et al., “Distinct localization of GABAB receptors relative
to synaptic sites in the rat cerebellum and ventrobasal thalamus,” European
Journal of Neuroscience, vol. 15, no. 2. Wiley-Blackwell, pp. 291–307, 2002.
ista: Kulik Á, Nakadate K, Nyíri G, Notomi T, Malitschek B, Bettler B, Shigemoto
R. 2002. Distinct localization of GABAB receptors relative to synaptic sites in
the rat cerebellum and ventrobasal thalamus. European Journal of Neuroscience.
15(2), 291–307.
mla: Kulik, Ákos, et al. “Distinct Localization of GABAB Receptors Relative to Synaptic
Sites in the Rat Cerebellum and Ventrobasal Thalamus.” European Journal of
Neuroscience, vol. 15, no. 2, Wiley-Blackwell, 2002, pp. 291–307, doi:10.1046/j.0953-816x.2001.01855.x.
short: Á. Kulik, K. Nakadate, G. Nyíri, T. Notomi, B. Malitschek, B. Bettler, R.
Shigemoto, European Journal of Neuroscience 15 (2002) 291–307.
date_created: 2018-12-11T11:58:44Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-07-18T13:08:40Z
day: '01'
doi: 10.1046/j.0953-816x.2001.01855.x
extern: '1'
external_id:
pmid:
- '11849296'
intvolume: ' 15'
issue: '2'
language:
- iso: eng
month: '01'
oa_version: None
page: 291 - 307
pmid: 1
publication: European Journal of Neuroscience
publication_identifier:
issn:
- 0953-816X
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4275'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Distinct localization of GABAB receptors relative to synaptic sites in the
rat cerebellum and ventrobasal thalamus
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 15
year: '2002'
...
---
_id: '2694'
abstract:
- lang: eng
text: We outline the status of rigorous derivations of certain classical evolution
equations as limits of Schrödinger dynamics. We explain two recent results jointly
with H.T. Yau in more details. The first one is the derivation of the linear Boltzmann
equation as the long time limit of the one-body Schrödinger equation with a random
potential. The second one is the mean field limit of high density bosons with
Coulomb interaction that leads to the nonlinear Hartree equation.
alternative_title:
- LNP
article_processing_charge: No
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
citation:
ama: 'Erdös L. Scaling limits of Schrödinger quantum mechanics. In: Dynamics
of Dissipation. Lecture Notes in Physics. Springer; 2002:487-506. doi:10.1007/3-540-46122-1_19'
apa: Erdös, L. (2002). Scaling limits of Schrödinger quantum mechanics. In Dynamics
of Dissipation (pp. 487–506). Springer. https://doi.org/10.1007/3-540-46122-1_19
chicago: Erdös, László. “Scaling Limits of Schrödinger Quantum Mechanics.” In Dynamics
of Dissipation, 487–506. Lecture Notes in Physics. Springer, 2002. https://doi.org/10.1007/3-540-46122-1_19.
ieee: L. Erdös, “Scaling limits of Schrödinger quantum mechanics,” in Dynamics
of Dissipation, Springer, 2002, pp. 487–506.
ista: 'Erdös L. 2002.Scaling limits of Schrödinger quantum mechanics. In: Dynamics
of Dissipation. LNP, , 487–506.'
mla: Erdös, László. “Scaling Limits of Schrödinger Quantum Mechanics.” Dynamics
of Dissipation, Springer, 2002, pp. 487–506, doi:10.1007/3-540-46122-1_19.
short: L. Erdös, in:, Dynamics of Dissipation, Springer, 2002, pp. 487–506.
conference:
name: '38th Winter School of Theoretical Physics : Dynamical Semigroups: Dissipation,
Chaos, Quanta'
date_created: 2018-12-11T11:59:06Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-07-18T10:23:18Z
day: '01'
doi: 10.1007/3-540-46122-1_19
extern: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 487 - 506
publication: Dynamics of Dissipation
publication_identifier:
isbn:
- '9783540441113'
publication_status: published
publisher: Springer
publist_id: '4203'
quality_controlled: '1'
series_title: Lecture Notes in Physics
status: public
title: Scaling limits of Schrödinger quantum mechanics
type: book_chapter
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '2002'
...
---
_id: '2622'
abstract:
- lang: eng
text: To understand the possible contribution of metabotropic γ-aminobutyric acid
receptors (GABABR) in cortical development, we investigated the expression pattern
and the cellular and subcellular localization of the GABABR1 and GABABR2 subtypes
in the rat neocortex from embryonic day 14 (E14) to adulthood. At the light microscopic
level, both GABABR1 and GABABR2 were detected as early as E14. During prenatal
development, both subtypes were expressed highly in the cortical plate. Using
double immunofluorescence, GABABR1 colocalized with GABABR2 in neurons of the
marginal zone and subplate, indicating that these proteins are coexpressed and
could be forming functional GABABRs during prenatal development in vivo. In contrast,
only GABABR1 but not GABABR2 was detected in the tangentially migratory cells
in the lower intermediate zone. During postnatal development, immunoreactivity
for GABABR1 and GABABR2 was distributed mainly in pyramidal cells. Discrete GABABR1-immunopositive
cell bodies of interneurons were present throughout the neocortex. In addition,
GABABR1 but not GABABR2 was found in identified Cajal-Retzius cells in layer I.
At the electron microscopic level, immunoreactivity for GABABR1 and GABABR2 was
found in dendritic spines and dendritic shafts at extrasynaptic and perisynaptic
sites throughout postnatal development. We further demonstrated the presynaptic
localization of GABABR1 and GABABR2, as well as the association of the receptors
with asymmetrical synaptic junctions. These results indicate potentially important
roles for the GABABRs in the regulation of migratory processes during corticogenesis
and in the modulation of synaptic transmission during early development of cortical
circuitry.
acknowledgement: The authors are grateful to Dr Marco Sassoe-Pogneto for his comments
on a previous version of the manuscript. We also would like to thank to Ms. Courtney
Voelker for the English revision and comments of the manuscript. This work was made
possible by grants from the European Community (QLG3-CT-1999–00192, R.L) and the
Spanish Ministry of Science and Technology (PB97-0582-CO2-01, A.F).
article_processing_charge: No
article_type: original
author:
- first_name: Guillermina
full_name: López Bendito, Guillermina
last_name: López Bendito
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Ákos
full_name: Kulik, Ákos
last_name: Kulik
- first_name: Ole
full_name: Paulsen, Ole
last_name: Paulsen
- first_name: Alfonso
full_name: Fairén, Alfonso
last_name: Fairén
- first_name: Rafael
full_name: Luján, Rafael
last_name: Luján
citation:
ama: López Bendito G, Shigemoto R, Kulik Á, Paulsen O, Fairén A, Luján R. Expression
and distribution of metabotropic GABA receptor subtypes GABABR1 and GABABR2 during
rat neocortical development. European Journal of Neuroscience. 2002;15(11):1766-1778.
doi:10.1046/j.1460-9568.2002.02032.x
apa: López Bendito, G., Shigemoto, R., Kulik, Á., Paulsen, O., Fairén, A., &
Luján, R. (2002). Expression and distribution of metabotropic GABA receptor subtypes
GABABR1 and GABABR2 during rat neocortical development. European Journal of
Neuroscience. Wiley-Blackwell. https://doi.org/10.1046/j.1460-9568.2002.02032.x
chicago: López Bendito, Guillermina, Ryuichi Shigemoto, Ákos Kulik, Ole Paulsen,
Alfonso Fairén, and Rafael Luján. “Expression and Distribution of Metabotropic
GABA Receptor Subtypes GABABR1 and GABABR2 during Rat Neocortical Development.”
European Journal of Neuroscience. Wiley-Blackwell, 2002. https://doi.org/10.1046/j.1460-9568.2002.02032.x.
ieee: G. López Bendito, R. Shigemoto, Á. Kulik, O. Paulsen, A. Fairén, and R. Luján,
“Expression and distribution of metabotropic GABA receptor subtypes GABABR1 and
GABABR2 during rat neocortical development,” European Journal of Neuroscience,
vol. 15, no. 11. Wiley-Blackwell, pp. 1766–1778, 2002.
ista: López Bendito G, Shigemoto R, Kulik Á, Paulsen O, Fairén A, Luján R. 2002.
Expression and distribution of metabotropic GABA receptor subtypes GABABR1 and
GABABR2 during rat neocortical development. European Journal of Neuroscience.
15(11), 1766–1778.
mla: López Bendito, Guillermina, et al. “Expression and Distribution of Metabotropic
GABA Receptor Subtypes GABABR1 and GABABR2 during Rat Neocortical Development.”
European Journal of Neuroscience, vol. 15, no. 11, Wiley-Blackwell, 2002,
pp. 1766–78, doi:10.1046/j.1460-9568.2002.02032.x.
short: G. López Bendito, R. Shigemoto, Á. Kulik, O. Paulsen, A. Fairén, R. Luján,
European Journal of Neuroscience 15 (2002) 1766–1778.
date_created: 2018-12-11T11:58:43Z
date_published: 2002-06-01T00:00:00Z
date_updated: 2023-07-19T07:30:39Z
day: '01'
doi: 10.1046/j.1460-9568.2002.02032.x
extern: '1'
external_id:
pmid:
- '12081656'
intvolume: ' 15'
issue: '11'
language:
- iso: eng
month: '06'
oa_version: None
page: 1766 - 1778
pmid: 1
publication: European Journal of Neuroscience
publication_identifier:
issn:
- 0953-816X
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4276'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Expression and distribution of metabotropic GABA receptor subtypes GABABR1
and GABABR2 during rat neocortical development
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 15
year: '2002'
...