--- _id: '4349' abstract: - lang: eng text: 'Bayesian inference is becoming a common statistical approach to phylogenetic estimation because, among other reasons, it allows for rapid analysis of large data sets with complex evolutionary models. Conveniently, Bayesian phylogenetic methods use currently available stochastic models of sequence evolution. However, as with other model-based approaches, the results of Bayesian inference are conditional on the assumed model of evolution: inadequate models (models that poorly fit the data) may result in erroneous inferences. In this article, I present a Bayesian phylogenetic method that evaluates the adequacy of evolutionary models using posterior predictive distributions. By evaluating a model''s posterior predictive performance, an adequate model can be selected for a Bayesian phylogenetic study. Although I present a single test statistic that assesses the overall (global) performance of a phylogenetic model, a variety of test statistics can be tailored to evaluate specific features (local performance) of evolutionary models to identify sources failure. The method presented here, unlike the likelihood-ratio test and parametric bootstrap, accounts for uncertainty in the phylogeny and model parameters.' acknowledgement: "This work was supported by grants from the NSF to John Huelsenbeck (MCB-0075404 and DEB0075406), to whom I am grateful for his support throughout this project. Also, I would like to express my deep thanks to Andrea Betancourt, John Huelsenbeck, Kelly Dyer, Rasmus Nielsen, and Frederick Ronquist for taking the time to read early versions of the\r\nmanuscript. Each and every one of them provided invaluable comments, that ultimately made the manuscript better. John Huelsenbeck, Bret Larget, Rasmus Nielsen, Ken Karol, and Andrea Betancourt patiently listened to me drone on about this project, and offered insightful comments that benefited this work, and for this they have my deepest gratitude. And finally, I would like to thank two anonymous reviewers who gave critical attention to the manuscript and provided valuable comments." article_processing_charge: No article_type: original author: - first_name: Jonathan P full_name: Bollback, Jonathan P id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87 last_name: Bollback orcid: 0000-0002-4624-4612 citation: ama: Bollback JP. Bayesian model adequacy and choice in phylogenetics. Molecular Biology and Evolution. 2002;19(7):1171-1180. doi:10.1093/oxfordjournals.molbev.a004175 apa: Bollback, J. P. (2002). Bayesian model adequacy and choice in phylogenetics. Molecular Biology and Evolution. Oxford University Press. https://doi.org/10.1093/oxfordjournals.molbev.a004175 chicago: Bollback, Jonathan P. “Bayesian Model Adequacy and Choice in Phylogenetics.” Molecular Biology and Evolution. Oxford University Press, 2002. https://doi.org/10.1093/oxfordjournals.molbev.a004175. ieee: J. P. Bollback, “Bayesian model adequacy and choice in phylogenetics,” Molecular Biology and Evolution, vol. 19, no. 7. Oxford University Press, pp. 1171–80, 2002. ista: Bollback JP. 2002. Bayesian model adequacy and choice in phylogenetics. Molecular Biology and Evolution. 19(7), 1171–80. mla: Bollback, Jonathan P. “Bayesian Model Adequacy and Choice in Phylogenetics.” Molecular Biology and Evolution, vol. 19, no. 7, Oxford University Press, 2002, pp. 1171–80, doi:10.1093/oxfordjournals.molbev.a004175. short: J.P. Bollback, Molecular Biology and Evolution 19 (2002) 1171–80. date_created: 2018-12-11T12:08:24Z date_published: 2002-03-25T00:00:00Z date_updated: 2023-06-06T09:18:18Z day: '25' doi: 10.1093/oxfordjournals.molbev.a004175 extern: '1' external_id: pmid: - '12082136 ' intvolume: ' 19' issue: '7' language: - iso: eng month: '03' oa_version: None page: 1171 - 80 pmid: 1 publication: Molecular Biology and Evolution publication_identifier: issn: - 0737-4038 publication_status: published publisher: Oxford University Press publist_id: '1112' quality_controlled: '1' scopus_import: '1' status: public title: Bayesian model adequacy and choice in phylogenetics type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 19 year: '2002' ... --- _id: '4263' abstract: - lang: eng text: 'We introduce a general recursion for the probability of identity in state of two individuals sampled from a population subject to mutation, migration, and random drift in a two-dimensional continuum. The recursion allows for the interactions induced by density-dependent regulation of the population, which are inevitable in a continuous population. We give explicit series expansions for large neighbourhood size and for low mutation rates respectively and investigate the accuracy of the classical Malécot formula for these general models. When neighbourhood size is small, this formula does not give the identity even over large scales. However, for large neighbourhood size, it is an accurate approximation which summarises the local population structure in terms of three quantities: the effective dispersal rate, σe; the effective population density, ρe; and a local scale, κ, at which local interactions become significant. The results are illustrated by simulations.' acknowledgement: This work was supported by grants from the EPSRC (GR/L10048 and an advanced fellowship for A.M.E.) and NERC (GR3/11635) and by the Darwin Trust of Edinburgh. We thank Anja Sturm for her assistance with the project and anonymous reviewers for helpful comments. This paper is dedicated to Charlotte, A.M.E.’s daughter born during the gestation of the manuscript. article_processing_charge: No article_type: original author: - first_name: Nicholas H full_name: Barton, Nicholas H id: 4880FE40-F248-11E8-B48F-1D18A9856A87 last_name: Barton orcid: 0000-0002-8548-5240 - first_name: Frantz full_name: Depaulis, Frantz last_name: Depaulis - first_name: Alison full_name: Etheridge, Alison last_name: Etheridge citation: ama: Barton NH, Depaulis F, Etheridge A. Neutral evolution in spatially continuous populations. Theoretical Population Biology. 2002;61(1):31-48. doi:10.1006/tpbi.2001.1557 apa: Barton, N. H., Depaulis, F., & Etheridge, A. (2002). Neutral evolution in spatially continuous populations. Theoretical Population Biology. Academic Press. https://doi.org/10.1006/tpbi.2001.1557 chicago: Barton, Nicholas H, Frantz Depaulis, and Alison Etheridge. “Neutral Evolution in Spatially Continuous Populations.” Theoretical Population Biology. Academic Press, 2002. https://doi.org/10.1006/tpbi.2001.1557. ieee: N. H. Barton, F. Depaulis, and A. Etheridge, “Neutral evolution in spatially continuous populations,” Theoretical Population Biology, vol. 61, no. 1. Academic Press, pp. 31–48, 2002. ista: Barton NH, Depaulis F, Etheridge A. 2002. Neutral evolution in spatially continuous populations. Theoretical Population Biology. 61(1), 31–48. mla: Barton, Nicholas H., et al. “Neutral Evolution in Spatially Continuous Populations.” Theoretical Population Biology, vol. 61, no. 1, Academic Press, 2002, pp. 31–48, doi:10.1006/tpbi.2001.1557. short: N.H. Barton, F. Depaulis, A. Etheridge, Theoretical Population Biology 61 (2002) 31–48. date_created: 2018-12-11T12:07:55Z date_published: 2002-02-01T00:00:00Z date_updated: 2023-06-06T09:57:49Z day: '01' doi: 10.1006/tpbi.2001.1557 extern: '1' external_id: pmid: - '11895381' intvolume: ' 61' issue: '1' language: - iso: eng month: '02' oa_version: None page: 31 - 48 pmid: 1 publication: Theoretical Population Biology publication_identifier: issn: - 0040-5809 publication_status: published publisher: Academic Press publist_id: '1830' quality_controlled: '1' scopus_import: '1' status: public title: Neutral evolution in spatially continuous populations type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 61 year: '2002' ... --- _id: '4261' abstract: - lang: eng text: Until recently, it was impracticable to identify the genes that are responsible for variation in continuous traits, or to directly observe the effects of their different alleles. Now, the abundance of genetic markers has made it possible to identify quantitative trait loci (QTL) — the regions of a chromosome or, ideally, individual sequence variants that are responsible for trait variation. What kind of QTL do we expect to find and what can our observations of QTL tell us about how organisms evolve? The key to understanding the evolutionary significance of QTL is to understand the nature of inherited variation, not in the immediate mechanistic sense of how genes influence phenotype, but, rather, to know what evolutionary forces maintain genetic variability. article_processing_charge: No article_type: original author: - first_name: Nicholas H full_name: Barton, Nicholas H id: 4880FE40-F248-11E8-B48F-1D18A9856A87 last_name: Barton orcid: 0000-0002-8548-5240 - first_name: Peter full_name: Keightley, Peter last_name: Keightley citation: ama: Barton NH, Keightley P. Understanding quantitative genetic variation. Nature Reviews Genetics. 2002;3:11-21. doi:10.1038/nrg700 apa: Barton, N. H., & Keightley, P. (2002). Understanding quantitative genetic variation. Nature Reviews Genetics. Nature Publishing Group. https://doi.org/10.1038/nrg700 chicago: Barton, Nicholas H, and Peter Keightley. “Understanding Quantitative Genetic Variation.” Nature Reviews Genetics. Nature Publishing Group, 2002. https://doi.org/10.1038/nrg700. ieee: N. H. Barton and P. Keightley, “Understanding quantitative genetic variation,” Nature Reviews Genetics, vol. 3. Nature Publishing Group, pp. 11–21, 2002. ista: Barton NH, Keightley P. 2002. Understanding quantitative genetic variation. Nature Reviews Genetics. 3, 11–21. mla: Barton, Nicholas H., and Peter Keightley. “Understanding Quantitative Genetic Variation.” Nature Reviews Genetics, vol. 3, Nature Publishing Group, 2002, pp. 11–21, doi:10.1038/nrg700. short: N.H. Barton, P. Keightley, Nature Reviews Genetics 3 (2002) 11–21. date_created: 2018-12-11T12:07:55Z date_published: 2002-01-01T00:00:00Z date_updated: 2023-06-06T10:07:00Z day: '01' doi: 10.1038/nrg700 extern: '1' external_id: pmid: - '11823787' intvolume: ' 3' language: - iso: eng month: '01' oa_version: None page: 11 - 21 pmid: 1 publication: Nature Reviews Genetics publication_identifier: issn: - 1471-0056 publication_status: published publisher: Nature Publishing Group publist_id: '1831' quality_controlled: '1' scopus_import: '1' status: public title: Understanding quantitative genetic variation type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 3 year: '2002' ... --- _id: '4347' abstract: - lang: eng text: 'Phylogenetic trees can be rooted by a number of criteria. Here, we introduce a Bayesian method for inferring the root of a phylogenetic tree by using one of several criteria: the outgroup, molecular clock, and nonreversible model of DNA substitution. We perform simulation analyses to examine the relative ability of these three criteria to correctly identify the root of the tree. The outgroup and molecular clock criteria were best able to identify the root of the tree, whereas the nonreversible model was able to identify the root only when the substitution process was highly nonreversible. We also examined the performance of the criteria for a tree of four species for which the topology and root position are well supported. Results of the analyses of these data are consistent with the simulation results.' article_processing_charge: No article_type: original author: - first_name: John full_name: Huelsenbeck, John last_name: Huelsenbeck - first_name: Jonathan P full_name: Bollback, Jonathan P id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87 last_name: Bollback orcid: 0000-0002-4624-4612 - first_name: Amy full_name: Levine, Amy last_name: Levine citation: ama: Huelsenbeck J, Bollback JP, Levine A. Inferring the root of a phylogenetic tree. Systematic Biology. 2002;51(1):32-43. doi:10.1080/106351502753475862 apa: Huelsenbeck, J., Bollback, J. P., & Levine, A. (2002). Inferring the root of a phylogenetic tree. Systematic Biology. Oxford University Press. https://doi.org/10.1080/106351502753475862 chicago: Huelsenbeck, John, Jonathan P Bollback, and Amy Levine. “Inferring the Root of a Phylogenetic Tree.” Systematic Biology. Oxford University Press, 2002. https://doi.org/10.1080/106351502753475862. ieee: J. Huelsenbeck, J. P. Bollback, and A. Levine, “Inferring the root of a phylogenetic tree,” Systematic Biology, vol. 51, no. 1. Oxford University Press, pp. 32–43, 2002. ista: Huelsenbeck J, Bollback JP, Levine A. 2002. Inferring the root of a phylogenetic tree. Systematic Biology. 51(1), 32–43. mla: Huelsenbeck, John, et al. “Inferring the Root of a Phylogenetic Tree.” Systematic Biology, vol. 51, no. 1, Oxford University Press, 2002, pp. 32–43, doi:10.1080/106351502753475862. short: J. Huelsenbeck, J.P. Bollback, A. Levine, Systematic Biology 51 (2002) 32–43. date_created: 2018-12-11T12:08:23Z date_published: 2002-02-01T00:00:00Z date_updated: 2023-06-06T09:53:27Z day: '01' doi: 10.1080/106351502753475862 extern: '1' external_id: pmid: - '11943091' intvolume: ' 51' issue: '1' language: - iso: eng month: '02' oa_version: None page: 32 - 43 pmid: 1 publication: Systematic Biology publication_identifier: issn: - 0039-7989 publication_status: published publisher: Oxford University Press publist_id: '1113' quality_controlled: '1' scopus_import: '1' status: public title: Inferring the root of a phylogenetic tree type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 51 year: '2002' ... --- _id: '4407' abstract: - lang: eng text: 'This paper presents a complete axiomatization of two decidable propositional real-time linear temporal logics: Event Clock Logic (EventClockTL) and Metric Interval Temporal Logic with past (MetricIntervalTL). The completeness proof consists of an effective proof building procedure for EventClockTL. From this result we obtain a complete axiomatization of MetricIntervalTL by providing axioms translating MetricIntervalTL formulae into EventClockTL formulae, the two logics being equally expressive. Our proof is structured to yield axiomatizations also for interesting fragments of these logics, such as the linear temporal logic of the real numbers (TLR).' article_processing_charge: No article_type: original author: - first_name: Jean full_name: Raskin, Jean last_name: Raskin - first_name: Pierre full_name: Schobbens, Pierre last_name: Schobbens - first_name: Thomas A full_name: Henzinger, Thomas A id: 40876CD8-F248-11E8-B48F-1D18A9856A87 last_name: Henzinger orcid: 0000−0002−2985−7724 citation: ama: Raskin J, Schobbens P, Henzinger TA. Axioms for real-time logics. Theoretical Computer Science. 2002;274(1-2):151-182. doi:10.1016/S0304-3975(00)00308-X apa: Raskin, J., Schobbens, P., & Henzinger, T. A. (2002). Axioms for real-time logics. Theoretical Computer Science. Elsevier. https://doi.org/10.1016/S0304-3975(00)00308-X chicago: Raskin, Jean, Pierre Schobbens, and Thomas A Henzinger. “Axioms for Real-Time Logics.” Theoretical Computer Science. Elsevier, 2002. https://doi.org/10.1016/S0304-3975(00)00308-X. ieee: J. Raskin, P. Schobbens, and T. A. Henzinger, “Axioms for real-time logics,” Theoretical Computer Science, vol. 274, no. 1–2. Elsevier, pp. 151–182, 2002. ista: Raskin J, Schobbens P, Henzinger TA. 2002. Axioms for real-time logics. Theoretical Computer Science. 274(1–2), 151–182. mla: Raskin, Jean, et al. “Axioms for Real-Time Logics.” Theoretical Computer Science, vol. 274, no. 1–2, Elsevier, 2002, pp. 151–82, doi:10.1016/S0304-3975(00)00308-X. short: J. Raskin, P. Schobbens, T.A. Henzinger, Theoretical Computer Science 274 (2002) 151–182. date_created: 2018-12-11T12:08:42Z date_published: 2002-03-01T00:00:00Z date_updated: 2023-06-06T09:10:56Z day: '01' doi: 10.1016/S0304-3975(00)00308-X extern: '1' intvolume: ' 274' issue: 1-2 language: - iso: eng month: '03' oa_version: None page: 151 - 182 publication: Theoretical Computer Science publication_identifier: issn: - 0304-3975 publication_status: published publisher: Elsevier publist_id: '324' quality_controlled: '1' scopus_import: '1' status: public title: Axioms for real-time logics type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 274 year: '2002' ... --- _id: '4258' abstract: - lang: eng text: We studied the effect of multilocus balancing selection on neutral nucleotide variability at linked sites by simulating a model where diallelic polymorphisms are maintained at an arbitrary number of selected loci by means of symmetric overdominance. Different combinations of alleles define different genetic backgrounds that subdivide the population and strongly affect variability. Several multilocus fitness regimes with different degrees of epistasis and gametic disequilibrium are allowed. Analytical results based on a multilocus extension of the structured coalescent predict that the expected linked neutral diversity increases exponentially with the number of selected loci and can become extremely large. Our simulation results show that although variability increases with the number of genetic backgrounds that are maintained in the population, it is reduced by random fluctuations in the frequencies of those backgrounds and does not reach high levels even in very large populations. We also show that previous results on balancing selection in single-locus systems do not extend to the multilocus scenario in a straightforward way. Different patterns of linkage disequilibrium and of the frequency spectrum of neutral mutations are expected under different degrees of epistasis. Interestingly, the power to detect balancing selection using deviations from a neutral distribution of allele frequencies seems to be diminished under the fitness regime that leads to the largest increase of variability over the neutral case. This and other results are discussed in the light of data from the Mhc. acknowledgement: We thank P. Andolfatto, P. Awadalla, B. Charlesworth, D. Charles- Guillaudeux, T., M. Janer, G. K. S. Wong, T. Spies and D. E. Geraghty, F. Depaulis, S. Otto, J. Rozas, and three anonymous reviewers for valuable discussion and criticism. A.N. is grateful to F. Depaulis, whose comments were particularly helpful (and extremely funny), and to D. Charlesworth, whose ideas made this work readable. This work was supported by Biotechnology and Biological Sciences Research Council/Engineering and Physical Sciences Research Council. article_processing_charge: No article_type: original author: - first_name: Arcadio full_name: Navarro, Arcadio last_name: Navarro - first_name: Nicholas H full_name: Barton, Nicholas H id: 4880FE40-F248-11E8-B48F-1D18A9856A87 last_name: Barton orcid: 0000-0002-8548-5240 citation: ama: Navarro A, Barton NH. The effects of multilocus balancing selection on neutral variability. Genetics. 2002;161(2):849-863. doi:10.1093/genetics/161.2.849 apa: Navarro, A., & Barton, N. H. (2002). The effects of multilocus balancing selection on neutral variability. Genetics. Genetics Society of America. https://doi.org/10.1093/genetics/161.2.849 chicago: Navarro, Arcadio, and Nicholas H Barton. “The Effects of Multilocus Balancing Selection on Neutral Variability.” Genetics. Genetics Society of America, 2002. https://doi.org/10.1093/genetics/161.2.849. ieee: A. Navarro and N. H. Barton, “The effects of multilocus balancing selection on neutral variability,” Genetics, vol. 161, no. 2. Genetics Society of America, pp. 849–863, 2002. ista: Navarro A, Barton NH. 2002. The effects of multilocus balancing selection on neutral variability. Genetics. 161(2), 849–863. mla: Navarro, Arcadio, and Nicholas H. Barton. “The Effects of Multilocus Balancing Selection on Neutral Variability.” Genetics, vol. 161, no. 2, Genetics Society of America, 2002, pp. 849–63, doi:10.1093/genetics/161.2.849. short: A. Navarro, N.H. Barton, Genetics 161 (2002) 849–863. date_created: 2018-12-11T12:07:53Z date_published: 2002-06-01T00:00:00Z date_updated: 2023-06-06T12:02:32Z day: '01' doi: 10.1093/genetics/161.2.849 extern: '1' external_id: pmid: - '12072479' intvolume: ' 161' issue: '2' language: - iso: eng main_file_link: - open_access: '1' url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462137/ month: '06' oa: 1 oa_version: Published Version page: 849 - 863 pmid: 1 publication: Genetics publication_identifier: issn: - 0016-6731 publication_status: published publisher: Genetics Society of America publist_id: '1835' quality_controlled: '1' scopus_import: '1' status: public title: The effects of multilocus balancing selection on neutral variability type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 161 year: '2002' ... --- _id: '4259' abstract: - lang: eng text: 'We extend current multilocus models to describe the effects of migration, recombination, selection, and nonrandom mating on sets of genes in diploids with varied modes of inheritance, allowing us to consider the patterns of nuclear and cytonuclear associations (disequilibria) under various models of migration. We show the relationship between the multilocus notation recently presented by Kirkpatrick, Johnson, and Barton (developed from previous work by Barton and Turelli) and the cytonuclear parameterization of Asmussen, Arnold, and Avise and extend this notation to describe associations between cytoplasmic elements and multiple nuclear genes. Under models with sexual symmetry, both nuclear-nuclear and cytonuclear disequilibria are equivalent. They differ, however, in cases involving some type of sexual asymmetry, which is then reflected in the asymmetric inheritance of cytoplasmic markers. An example given is the case of different migration rates in males and females; simulations using 2, 3, 4, or 5 unlinked autosomal markers with a maternally inherited cytoplasmic marker illustrate how nuclear-nuclear and cytonuclear associations can be used to separately estimate female and male migration rates. The general framework developed here allows us to investigate conditions where associations between loci with different modes of inheritance are not equivalent and to use this nonequivalence to test for deviations from simple models of admixture. ' acknowledgement: The authors thank Toby Johnson for his helpful comments on this manuscript. This work was supported by a National Science Foundation NATO postdoctoral fellowship and National Science Foundation grants DEB-9813335 and DEB-0108242 to M.E.O.; N.H.B. gratefully acknowledges the support of the Darwin Trust of Edinburgh and the National Environmental Research Council. article_processing_charge: No article_type: original author: - first_name: Maria full_name: Orive, Maria last_name: Orive - first_name: Nicholas H full_name: Barton, Nicholas H id: 4880FE40-F248-11E8-B48F-1D18A9856A87 last_name: Barton orcid: 0000-0002-8548-5240 citation: ama: Orive M, Barton NH. Associations between cytoplasmic and nuclear loci in hybridizing populations. Genetics. 2002;162(3):1469-1485. doi:10.1093/genetics/162.3.1469 apa: Orive, M., & Barton, N. H. (2002). Associations between cytoplasmic and nuclear loci in hybridizing populations. Genetics. Genetics Society of America. https://doi.org/10.1093/genetics/162.3.1469 chicago: Orive, Maria, and Nicholas H Barton. “Associations between Cytoplasmic and Nuclear Loci in Hybridizing Populations.” Genetics. Genetics Society of America, 2002. https://doi.org/10.1093/genetics/162.3.1469. ieee: M. Orive and N. H. Barton, “Associations between cytoplasmic and nuclear loci in hybridizing populations,” Genetics, vol. 162, no. 3. Genetics Society of America, pp. 1469–1485, 2002. ista: Orive M, Barton NH. 2002. Associations between cytoplasmic and nuclear loci in hybridizing populations. Genetics. 162(3), 1469–1485. mla: Orive, Maria, and Nicholas H. Barton. “Associations between Cytoplasmic and Nuclear Loci in Hybridizing Populations.” Genetics, vol. 162, no. 3, Genetics Society of America, 2002, pp. 1469–85, doi:10.1093/genetics/162.3.1469. short: M. Orive, N.H. Barton, Genetics 162 (2002) 1469–1485. date_created: 2018-12-11T12:07:54Z date_published: 2002-11-01T00:00:00Z date_updated: 2023-06-06T12:19:54Z day: '01' doi: 10.1093/genetics/162.3.1469 extern: '1' external_id: pmid: - '12454089' intvolume: ' 162' issue: '3' language: - iso: eng main_file_link: - open_access: '1' url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462324/ month: '11' oa: 1 oa_version: Published Version page: 1469 - 1485 pmid: 1 publication: Genetics publication_identifier: issn: - 0016-6731 publication_status: published publisher: Genetics Society of America publist_id: '1836' quality_controlled: '1' scopus_import: '1' status: public title: Associations between cytoplasmic and nuclear loci in hybridizing populations type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 162 year: '2002' ... --- _id: '4209' abstract: - lang: eng text: We have identified widerborst (wdb), a B' regulatory subunit of PP2A, as a conserved component of planar cell polarization mechanisms in both Drosophila and in zebrafish. In Drosophila, wdb acts at two steps during planar polarization of wing epithelial cells. It is required to organize tissue polarity proteins into proximal and distal cortical domains, thus determining wing hair orientation. It is also needed to generate the polarized membrane outgrowth that becomes the wing hair. Widerborst activates the catalytic subunit of PP2A and localizes to the distal side of a planar microtubule web that lies at the level of apical cell junctions. This suggests that polarized PP2A activation along the planar microtubule web is important for planar polarization. In zebrafish, two wdb homologs are required for convergent extension during gastrulation, supporting the conjecture that Drosophila planar cell polarization and vertebrate gastrulation movements are regulated by similar mechanisms. acknowledgement: We gratefully acknowledge Bianca Habermann for assistance with bioinformatics, Jens Rietdorf and Arshad Desai for help with deconvolution, and Tadashi Uemura and Rick Fehon for providing antibodies. Arshad Desai, Christian Dahmann, Tony Hyman and Elly Tanaka provided helpful comments on the manuscript. Part of this work was performed at the EMBL in Heidelberg. article_processing_charge: No article_type: original author: - first_name: Michael full_name: Hannus, Michael last_name: Hannus - first_name: Fabian full_name: Feiguin, Fabian last_name: Feiguin - first_name: Carl-Philipp J full_name: Heisenberg, Carl-Philipp J id: 39427864-F248-11E8-B48F-1D18A9856A87 last_name: Heisenberg orcid: 0000-0002-0912-4566 - first_name: Suzanne full_name: Eaton, Suzanne last_name: Eaton citation: ama: Hannus M, Feiguin F, Heisenberg C-PJ, Eaton S. Planar cell polarization requires Widerborst, a B′ regulatory subunit of protein phosphatase 2A. Development. 2002;129(14):3493-3503. doi:10.1242/dev.129.14.3493 apa: Hannus, M., Feiguin, F., Heisenberg, C.-P. J., & Eaton, S. (2002). Planar cell polarization requires Widerborst, a B′ regulatory subunit of protein phosphatase 2A. Development. Company of Biologists. https://doi.org/10.1242/dev.129.14.3493 chicago: Hannus, Michael, Fabian Feiguin, Carl-Philipp J Heisenberg, and Suzanne Eaton. “Planar Cell Polarization Requires Widerborst, a B′ Regulatory Subunit of Protein Phosphatase 2A.” Development. Company of Biologists, 2002. https://doi.org/10.1242/dev.129.14.3493. ieee: M. Hannus, F. Feiguin, C.-P. J. Heisenberg, and S. Eaton, “Planar cell polarization requires Widerborst, a B′ regulatory subunit of protein phosphatase 2A,” Development, vol. 129, no. 14. Company of Biologists, pp. 3493–3503, 2002. ista: Hannus M, Feiguin F, Heisenberg C-PJ, Eaton S. 2002. Planar cell polarization requires Widerborst, a B′ regulatory subunit of protein phosphatase 2A. Development. 129(14), 3493–3503. mla: Hannus, Michael, et al. “Planar Cell Polarization Requires Widerborst, a B′ Regulatory Subunit of Protein Phosphatase 2A.” Development, vol. 129, no. 14, Company of Biologists, 2002, pp. 3493–503, doi:10.1242/dev.129.14.3493. short: M. Hannus, F. Feiguin, C.-P.J. Heisenberg, S. Eaton, Development 129 (2002) 3493–3503. date_created: 2018-12-11T12:07:36Z date_published: 2002-07-15T00:00:00Z date_updated: 2023-06-06T14:07:49Z day: '15' doi: 10.1242/dev.129.14.3493 extern: '1' external_id: pmid: - '12091318' intvolume: ' 129' issue: '14' language: - iso: eng month: '07' oa_version: None page: 3493 - 3503 pmid: 1 publication: Development publication_identifier: issn: - 0950-1991 publication_status: published publisher: Company of Biologists publist_id: '1909' quality_controlled: '1' scopus_import: '1' status: public title: Planar cell polarization requires Widerborst, a B′ regulatory subunit of protein phosphatase 2A type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 129 year: '2002' ... --- _id: '4207' abstract: - lang: eng text: Vertebrate homologues of the Strabismus/van Gogh (stbm/vang) gene have been implicated in patterning and morphogenesis during gastrulation. Recent work shows that stbm/vang is mutated in zebrafish trilobite mutants and that stbm/vang is required for morphogenesis but not patterning during zebrafish gastrulation. article_processing_charge: No article_type: original author: - first_name: Carl-Philipp J full_name: Heisenberg, Carl-Philipp J id: 39427864-F248-11E8-B48F-1D18A9856A87 last_name: Heisenberg orcid: 0000-0002-0912-4566 citation: ama: 'Heisenberg C-PJ. Wnt signalling: Refocusing on Strabismus. Current Biology. 2002;12(19):R657-R659. doi:10.1016/S0960-9822(02)01160-0' apa: 'Heisenberg, C.-P. J. (2002). Wnt signalling: Refocusing on Strabismus. Current Biology. Cell Press. https://doi.org/10.1016/S0960-9822(02)01160-0' chicago: 'Heisenberg, Carl-Philipp J. “Wnt Signalling: Refocusing on Strabismus.” Current Biology. Cell Press, 2002. https://doi.org/10.1016/S0960-9822(02)01160-0.' ieee: 'C.-P. J. Heisenberg, “Wnt signalling: Refocusing on Strabismus,” Current Biology, vol. 12, no. 19. Cell Press, pp. R657–R659, 2002.' ista: 'Heisenberg C-PJ. 2002. Wnt signalling: Refocusing on Strabismus. Current Biology. 12(19), R657–R659.' mla: 'Heisenberg, Carl-Philipp J. “Wnt Signalling: Refocusing on Strabismus.” Current Biology, vol. 12, no. 19, Cell Press, 2002, pp. R657–59, doi:10.1016/S0960-9822(02)01160-0.' short: C.-P.J. Heisenberg, Current Biology 12 (2002) R657–R659. date_created: 2018-12-11T12:07:35Z date_published: 2002-10-01T00:00:00Z date_updated: 2023-06-06T15:09:53Z day: '01' doi: 10.1016/S0960-9822(02)01160-0 extern: '1' external_id: pmid: - '12361585' intvolume: ' 12' issue: '19' language: - iso: eng month: '10' oa_version: None page: R657 - R659 pmid: 1 publication: Current Biology publication_identifier: issn: - 0960-9822 publication_status: published publisher: Cell Press publist_id: '1912' quality_controlled: '1' scopus_import: '1' status: public title: 'Wnt signalling: Refocusing on Strabismus' type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 12 year: '2002' ... --- _id: '4194' abstract: - lang: eng text: Cells at the anterior boundary of the neural plate (ANB) can induce telencephalic gene expression when transplanted to more posterior regions. Here, we identify a secreted Frizzled-related Wnt antagonist, Tic, that is expressed in ANB cells and can cell nonautonomously promote telencephalic gene expression in a concentration-dependent manner. Moreover, abrogation of Tlc function compromises telencephalic development. We also identify Wnt8b as a locally acting modulator of regional fate in the anterior neural plate and a likely target for antagonism by Tic. Finally, we show that tlc expression is regulated by signals that establish early antero-posterior and dorso-ventral ectodermal pattern. From these studies, we propose that local antagonism of Wnt activity within the anterior ectoderm is required to establish the telencephalon. acknowledgement: We thank many of our colleagues, especially Randy Moon, for providing reagents used in this study. This study was supported by the Wellcome Trust, MRC, and BBSRC to S.W.W. and C.H. S.W.W. is a Wellcome Trust Senior Research Fellow. article_processing_charge: No article_type: original author: - first_name: Corinne full_name: Houart, Corinne last_name: Houart - first_name: Luca full_name: Caneparo, Luca last_name: Caneparo - first_name: Carl-Philipp J full_name: Heisenberg, Carl-Philipp J id: 39427864-F248-11E8-B48F-1D18A9856A87 last_name: Heisenberg orcid: 0000-0002-0912-4566 - first_name: K Anukampa full_name: Barth, K Anukampa last_name: Barth - first_name: Masaya full_name: Take Uchi, Masaya last_name: Take Uchi - first_name: Stephen full_name: Wilson, Stephen last_name: Wilson citation: ama: Houart C, Caneparo L, Heisenberg C-PJ, Barth KA, Take Uchi M, Wilson S. Establishment of the telencephalon during gastrulation by local antagonism of Wnt signaling. Neuron. 2002;35(2):255-265. doi:10.1016/S0896-6273(02)00751-1 apa: Houart, C., Caneparo, L., Heisenberg, C.-P. J., Barth, K. A., Take Uchi, M., & Wilson, S. (2002). Establishment of the telencephalon during gastrulation by local antagonism of Wnt signaling. Neuron. Elsevier. https://doi.org/10.1016/S0896-6273(02)00751-1 chicago: Houart, Corinne, Luca Caneparo, Carl-Philipp J Heisenberg, K Anukampa Barth, Masaya Take Uchi, and Stephen Wilson. “Establishment of the Telencephalon during Gastrulation by Local Antagonism of Wnt Signaling.” Neuron. Elsevier, 2002. https://doi.org/10.1016/S0896-6273(02)00751-1. ieee: C. Houart, L. Caneparo, C.-P. J. Heisenberg, K. A. Barth, M. Take Uchi, and S. Wilson, “Establishment of the telencephalon during gastrulation by local antagonism of Wnt signaling,” Neuron, vol. 35, no. 2. Elsevier, pp. 255–265, 2002. ista: Houart C, Caneparo L, Heisenberg C-PJ, Barth KA, Take Uchi M, Wilson S. 2002. Establishment of the telencephalon during gastrulation by local antagonism of Wnt signaling. Neuron. 35(2), 255–265. mla: Houart, Corinne, et al. “Establishment of the Telencephalon during Gastrulation by Local Antagonism of Wnt Signaling.” Neuron, vol. 35, no. 2, Elsevier, 2002, pp. 255–65, doi:10.1016/S0896-6273(02)00751-1. short: C. Houart, L. Caneparo, C.-P.J. Heisenberg, K.A. Barth, M. Take Uchi, S. Wilson, Neuron 35 (2002) 255–265. date_created: 2018-12-11T12:07:30Z date_published: 2002-07-18T00:00:00Z date_updated: 2023-06-07T09:43:19Z day: '18' doi: 10.1016/S0896-6273(02)00751-1 extern: '1' external_id: pmid: - '12160744' intvolume: ' 35' issue: '2' language: - iso: eng month: '07' oa_version: None page: 255 - 265 pmid: 1 publication: Neuron publication_identifier: issn: - 0896-6273 publication_status: published publisher: Elsevier publist_id: '1925' quality_controlled: '1' scopus_import: '1' status: public title: Establishment of the telencephalon during gastrulation by local antagonism of Wnt signaling type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 35 year: '2002' ... --- _id: '4148' abstract: - lang: eng text: Members of the Wnt family have been implicated in a variety of developmental processes including axis formation, Patterning of the central nervous system and tissue morphogenesis. Recent studies have shown that a Wnt signalling pathway similar to that involved in the establishment of planar cell polarity in Drosophila regulates convergent extension movements during zebrafish and Xenopus gastrulation. This finding provides a good starting point to dissect the complex cell biology and genetic regulation of vertebrate gastrulation movements. acknowledgement: We would like to thank Steve Wilson for encouraging us to write this article and for critical comments on this manuscript, and Lila Solnica-Krezel for communicating results prior to publication. MT is supported by an MRC Career Development Award, MLC by a Wellcome Trust Fellowship and CPH by an Emmy–Noether–Fellowship from the DFG. article_processing_charge: No article_type: original author: - first_name: Masazumi full_name: Tada, Masazumi last_name: Tada - first_name: Miguel full_name: Concha, Miguel last_name: Concha - first_name: Carl-Philipp J full_name: Heisenberg, Carl-Philipp J id: 39427864-F248-11E8-B48F-1D18A9856A87 last_name: Heisenberg orcid: 0000-0002-0912-4566 citation: ama: Tada M, Concha M, Heisenberg C-PJ. Non-canonical Wnt signalling and regulation of gastrulation movements. Seminars in Cell & Developmental Biology. 2002;13(3):251-260. doi:10.1016/S1084-9521(02)00052-6 apa: Tada, M., Concha, M., & Heisenberg, C.-P. J. (2002). Non-canonical Wnt signalling and regulation of gastrulation movements. Seminars in Cell & Developmental Biology. Academic Press. https://doi.org/10.1016/S1084-9521(02)00052-6 chicago: Tada, Masazumi, Miguel Concha, and Carl-Philipp J Heisenberg. “Non-Canonical Wnt Signalling and Regulation of Gastrulation Movements.” Seminars in Cell & Developmental Biology. Academic Press, 2002. https://doi.org/10.1016/S1084-9521(02)00052-6. ieee: M. Tada, M. Concha, and C.-P. J. Heisenberg, “Non-canonical Wnt signalling and regulation of gastrulation movements,” Seminars in Cell & Developmental Biology, vol. 13, no. 3. Academic Press, pp. 251–260, 2002. ista: Tada M, Concha M, Heisenberg C-PJ. 2002. Non-canonical Wnt signalling and regulation of gastrulation movements. Seminars in Cell & Developmental Biology. 13(3), 251–260. mla: Tada, Masazumi, et al. “Non-Canonical Wnt Signalling and Regulation of Gastrulation Movements.” Seminars in Cell & Developmental Biology, vol. 13, no. 3, Academic Press, 2002, pp. 251–60, doi:10.1016/S1084-9521(02)00052-6. short: M. Tada, M. Concha, C.-P.J. Heisenberg, Seminars in Cell & Developmental Biology 13 (2002) 251–260. date_created: 2018-12-11T12:07:13Z date_published: 2002-06-01T00:00:00Z date_updated: 2023-06-07T09:50:14Z day: '01' doi: 10.1016/S1084-9521(02)00052-6 extern: '1' external_id: pmid: - '12137734' intvolume: ' 13' issue: '3' language: - iso: eng month: '06' oa_version: None page: 251 - 260 pmid: 1 publication: Seminars in Cell & Developmental Biology publication_identifier: issn: - 1084-9521 publication_status: published publisher: Academic Press publist_id: '1973' quality_controlled: '1' scopus_import: '1' status: public title: Non-canonical Wnt signalling and regulation of gastrulation movements type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 13 year: '2002' ... --- _id: '4196' abstract: - lang: eng text: During vertebrate gastrulation, large cellular rearrangements lead to the formation of the three germ layers, ectoderm, mesoderm and endoderm. Zebrafish offer many genetic and experimental advantages for studying vertebrate gastrulation movements. For instance, several mutants, including silberblick, knypek and trilobite, exhibit defects in morphogenesis during gastrulation. The identification of the genes mutated in these lines together with the analysis of the mutant phenotypes has provided new insights into the molecular and cellular mechanisms that underlie vertebrate gastrulation movements. acknowledgement: We would like to thank Miguel Concha, Will Norton, Tim Geach, Suzanne Eaton, Kimbo Kotovic, Jenny Geiger and Steve Wilson for critical comments on this manuscript, and Lila Solnica-Krezel for providing results prior to publication. C.-P.H. is supported by an Emmy-Noether-Fellowship from the DFG and M.T. by an MRC Career Development Award. article_processing_charge: No article_type: original author: - first_name: Carl-Philipp J full_name: Heisenberg, Carl-Philipp J id: 39427864-F248-11E8-B48F-1D18A9856A87 last_name: Heisenberg orcid: 0000-0002-0912-4566 - first_name: Masazumi full_name: Tada, Masazumi last_name: Tada citation: ama: 'Heisenberg C-PJ, Tada M. Zebrafish gastrulation movements: bridging cell and developmental biology. Seminars in Cell & Developmental Biology. 2002;13(6):471-479. doi:10.1016/S1084952102001003' apa: 'Heisenberg, C.-P. J., & Tada, M. (2002). Zebrafish gastrulation movements: bridging cell and developmental biology. Seminars in Cell & Developmental Biology. Academic Press. https://doi.org/10.1016/S1084952102001003' chicago: 'Heisenberg, Carl-Philipp J, and Masazumi Tada. “Zebrafish Gastrulation Movements: Bridging Cell and Developmental Biology.” Seminars in Cell & Developmental Biology. Academic Press, 2002. https://doi.org/10.1016/S1084952102001003.' ieee: 'C.-P. J. Heisenberg and M. Tada, “Zebrafish gastrulation movements: bridging cell and developmental biology,” Seminars in Cell & Developmental Biology, vol. 13, no. 6. Academic Press, pp. 471–479, 2002.' ista: 'Heisenberg C-PJ, Tada M. 2002. Zebrafish gastrulation movements: bridging cell and developmental biology. Seminars in Cell & Developmental Biology. 13(6), 471–479.' mla: 'Heisenberg, Carl-Philipp J., and Masazumi Tada. “Zebrafish Gastrulation Movements: Bridging Cell and Developmental Biology.” Seminars in Cell & Developmental Biology, vol. 13, no. 6, Academic Press, 2002, pp. 471–79, doi:10.1016/S1084952102001003.' short: C.-P.J. Heisenberg, M. Tada, Seminars in Cell & Developmental Biology 13 (2002) 471–479. date_created: 2018-12-11T12:07:31Z date_published: 2002-12-01T00:00:00Z date_updated: 2023-06-07T09:28:48Z day: '01' doi: 10.1016/S1084952102001003 extern: '1' external_id: pmid: - '12468250' intvolume: ' 13' issue: '6' language: - iso: eng month: '12' oa_version: None page: 471 - 479 pmid: 1 publication: Seminars in Cell & Developmental Biology publication_identifier: issn: - 1084-9521 publication_status: published publisher: Academic Press publist_id: '1920' quality_controlled: '1' scopus_import: '1' status: public title: 'Zebrafish gastrulation movements: bridging cell and developmental biology' type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 13 year: '2002' ... --- _id: '4199' abstract: - lang: eng text: Recent studies on vertebrate homologues of the van gogh/strabismus (vang/stbm) gene, a key player in planar cell polarity signalling in Drosophila, show that vang/stbm is involved in patterning and morphogenesis during vertebrate gastrulation where it modulates two distinct Wnt signals. article_processing_charge: No article_type: original author: - first_name: Carl-Philipp J full_name: Heisenberg, Carl-Philipp J id: 39427864-F248-11E8-B48F-1D18A9856A87 last_name: Heisenberg orcid: 0000-0002-0912-4566 - first_name: Masazumi full_name: Tada, Masazumi last_name: Tada citation: ama: 'Heisenberg C-PJ, Tada M. Wnt signalling: A moving picture emerges from van gogh. Current Biology. 2002;12(4):R126-R128. doi:10.1016/S0960-9822(02)00704-2' apa: 'Heisenberg, C.-P. J., & Tada, M. (2002). Wnt signalling: A moving picture emerges from van gogh. Current Biology. Cell Press. https://doi.org/10.1016/S0960-9822(02)00704-2' chicago: 'Heisenberg, Carl-Philipp J, and Masazumi Tada. “Wnt Signalling: A Moving Picture Emerges from van Gogh.” Current Biology. Cell Press, 2002. https://doi.org/10.1016/S0960-9822(02)00704-2.' ieee: 'C.-P. J. Heisenberg and M. Tada, “Wnt signalling: A moving picture emerges from van gogh,” Current Biology, vol. 12, no. 4. Cell Press, pp. R126–R128, 2002.' ista: 'Heisenberg C-PJ, Tada M. 2002. Wnt signalling: A moving picture emerges from van gogh. Current Biology. 12(4), R126–R128.' mla: 'Heisenberg, Carl-Philipp J., and Masazumi Tada. “Wnt Signalling: A Moving Picture Emerges from van Gogh.” Current Biology, vol. 12, no. 4, Cell Press, 2002, pp. R126–28, doi:10.1016/S0960-9822(02)00704-2.' short: C.-P.J. Heisenberg, M. Tada, Current Biology 12 (2002) R126–R128. date_created: 2018-12-11T12:07:32Z date_published: 2002-02-19T00:00:00Z date_updated: 2023-06-07T08:54:35Z day: '19' doi: 10.1016/S0960-9822(02)00704-2 extern: '1' external_id: pmid: - '11864583' intvolume: ' 12' issue: '4' language: - iso: eng month: '02' oa_version: None page: R126 - R128 pmid: 1 publication: Current Biology publication_identifier: issn: - 0960-9822 publication_status: published publisher: Cell Press publist_id: '1919' quality_controlled: '1' scopus_import: '1' status: public title: 'Wnt signalling: A moving picture emerges from van gogh' type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 12 year: '2002' ... --- _id: '4139' abstract: - lang: eng text: Pilot studies in England by Stopka and Macdonald revealed that allogrooming in the Old World wood mouse, Apodemus sylvaticus, is a commodity that males can trade for reproductive benefits with females. This study, which used a combination of field study and observations in experimental enclosures, revealed that specific experimental conditions such as group-size and sex-ratio manipulations have a significant effect on the pattern of allogrooming exchanged between individuals. Furthermore, females from the Czech population were more likely to associate with each other as revealed by the clustering of activity centers of females (i.e., as opposed to almost exclusive ranges in English populations), and also by the higher intensity of allogrooming exchanged between females (i.e., virtually lacking in the previous experiment with English mice). Therefore, geographic variation and specific social conditions seem to be important driving factors for allogrooming behavior. Together with changes in overall grooming patterns, allogrooming between males and females remained invariably asymmetrical over all four experimental groups (i.e., two conditions for each sex) in that males provided more allogrooming to females than they received from them. article_processing_charge: No article_type: original author: - first_name: Jitka full_name: Polechova, Jitka id: 3BBFB084-F248-11E8-B48F-1D18A9856A87 last_name: Polechova orcid: 0000-0003-0951-3112 - first_name: P. full_name: Stopka, P. last_name: Stopka citation: ama: Polechova J, Stopka P. Geometry of social relationships in the Old World wood mouse, Apodemus sylvaticus. Canadian Journal of Zoology. 2002;80(8):1383-1388. doi:10.1139/z02-128 apa: Polechova, J., & Stopka, P. (2002). Geometry of social relationships in the Old World wood mouse, Apodemus sylvaticus. Canadian Journal of Zoology. NRC Research Press. https://doi.org/10.1139/z02-128 chicago: Polechova, Jitka, and P. Stopka. “Geometry of Social Relationships in the Old World Wood Mouse, Apodemus Sylvaticus.” Canadian Journal of Zoology. NRC Research Press, 2002. https://doi.org/10.1139/z02-128. ieee: J. Polechova and P. Stopka, “Geometry of social relationships in the Old World wood mouse, Apodemus sylvaticus,” Canadian Journal of Zoology, vol. 80, no. 8. NRC Research Press, pp. 1383–1388, 2002. ista: Polechova J, Stopka P. 2002. Geometry of social relationships in the Old World wood mouse, Apodemus sylvaticus. Canadian Journal of Zoology. 80(8), 1383–1388. mla: Polechova, Jitka, and P. Stopka. “Geometry of Social Relationships in the Old World Wood Mouse, Apodemus Sylvaticus.” Canadian Journal of Zoology, vol. 80, no. 8, NRC Research Press, 2002, pp. 1383–88, doi:10.1139/z02-128. short: J. Polechova, P. Stopka, Canadian Journal of Zoology 80 (2002) 1383–1388. date_created: 2018-12-11T12:07:10Z date_published: 2002-01-01T00:00:00Z date_updated: 2023-06-07T12:53:35Z day: '01' doi: 10.1139/z02-128 extern: '1' intvolume: ' 80' issue: '8' language: - iso: eng month: '01' oa_version: None page: 1383 - 1388 publication: Canadian Journal of Zoology publication_identifier: issn: - 0008-4301 publication_status: published publisher: NRC Research Press publist_id: '1981' quality_controlled: '1' scopus_import: '1' status: public title: Geometry of social relationships in the Old World wood mouse, Apodemus sylvaticus type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 80 year: '2002' ... --- _id: '4003' abstract: - lang: eng text: The writhing number measures the global geometry of a closed space curve or knot. We show that this measure is related to the average winding number of its Gauss map. Using this relationship, we give an algorithm for computing the writhing number for a polygonal knot with n edges in time roughly proportional to n(1.6). We also implement a different, simple algorithm and provide experimental evidence for its practical efficiency. acknowledgement: NSF under grants CCR-00-86013 and EIA-9972879, NSF under grant CCR-97-12088. article_processing_charge: No author: - first_name: Pankaj full_name: Agarwal, Pankaj last_name: Agarwal - first_name: Herbert full_name: Edelsbrunner, Herbert id: 3FB178DA-F248-11E8-B48F-1D18A9856A87 last_name: Edelsbrunner orcid: 0000-0002-9823-6833 - first_name: Yusu full_name: Wang, Yusu last_name: Wang citation: ama: 'Agarwal P, Edelsbrunner H, Wang Y. Computing the writhing number of a polygonal knot. In: Proceedings of the 13th Annual ACM-SIAM Symposium on Discrete Algorithms. SIAM; 2002:791-799.' apa: 'Agarwal, P., Edelsbrunner, H., & Wang, Y. (2002). Computing the writhing number of a polygonal knot. In Proceedings of the 13th annual ACM-SIAM symposium on Discrete algorithms (pp. 791–799). San Francisco, CA, USA: SIAM.' chicago: Agarwal, Pankaj, Herbert Edelsbrunner, and Yusu Wang. “Computing the Writhing Number of a Polygonal Knot.” In Proceedings of the 13th Annual ACM-SIAM Symposium on Discrete Algorithms, 791–99. SIAM, 2002. ieee: P. Agarwal, H. Edelsbrunner, and Y. Wang, “Computing the writhing number of a polygonal knot,” in Proceedings of the 13th annual ACM-SIAM symposium on Discrete algorithms, San Francisco, CA, USA, 2002, pp. 791–799. ista: 'Agarwal P, Edelsbrunner H, Wang Y. 2002. Computing the writhing number of a polygonal knot. Proceedings of the 13th annual ACM-SIAM symposium on Discrete algorithms. SODA: Symposium on Discrete Algorithms, 791–799.' mla: Agarwal, Pankaj, et al. “Computing the Writhing Number of a Polygonal Knot.” Proceedings of the 13th Annual ACM-SIAM Symposium on Discrete Algorithms, SIAM, 2002, pp. 791–99. short: P. Agarwal, H. Edelsbrunner, Y. Wang, in:, Proceedings of the 13th Annual ACM-SIAM Symposium on Discrete Algorithms, SIAM, 2002, pp. 791–799. conference: end_date: 2002-01-08 location: San Francisco, CA, USA name: 'SODA: Symposium on Discrete Algorithms' start_date: 2002-01-06 date_created: 2018-12-11T12:06:23Z date_published: 2002-01-01T00:00:00Z date_updated: 2023-06-07T13:50:04Z day: '01' extern: '1' language: - iso: eng main_file_link: - url: https://dl.acm.org/doi/10.5555/545381.545485 month: '01' oa_version: None page: 791 - 799 publication: Proceedings of the 13th annual ACM-SIAM symposium on Discrete algorithms publication_identifier: isbn: - '9780898715132' publication_status: published publisher: SIAM publist_id: '2125' quality_controlled: '1' scopus_import: '1' status: public title: Computing the writhing number of a polygonal knot type: conference user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 year: '2002' ... --- _id: '3995' abstract: - lang: eng text: This article is a survey of research areas in which motion plays a pivotal role. The aim of the article is to review current approaches to modeling motion together with related data structures and algorithms, and to summarize the challenges that lie ahead in producing a more unified theory of motion representation that would be useful across several disciplines. acknowledgement: "This article is based on the report of the Workshop on Algorithmic Issues in Modeling Motion, sponsored\r\nby an NSF grant CCR-00-83-033 and an Army Research Office grant DAAD 19-00-1-0478, held on August 6\r\nand 7, 2000 at Duke University, Durham, NC." article_processing_charge: No article_type: original author: - first_name: Pankaj full_name: Agarwal, Pankaj last_name: Agarwal - first_name: Leonidas full_name: Guibas, Leonidas last_name: Guibas - first_name: Herbert full_name: Edelsbrunner, Herbert id: 3FB178DA-F248-11E8-B48F-1D18A9856A87 last_name: Edelsbrunner orcid: 0000-0002-9823-6833 - first_name: Jeff full_name: Erickson, Jeff last_name: Erickson - first_name: Michael full_name: Isard, Michael last_name: Isard - first_name: Sariel full_name: Har Peled, Sariel last_name: Har Peled - first_name: John full_name: Hershberger, John last_name: Hershberger - first_name: Christian full_name: Jensen, Christian last_name: Jensen - first_name: Lydia full_name: Kavraki, Lydia last_name: Kavraki - first_name: Patrice full_name: Koehl, Patrice last_name: Koehl - first_name: Ming full_name: Lin, Ming last_name: Lin - first_name: Dinesh full_name: Manocha, Dinesh last_name: Manocha - first_name: Dimitris full_name: Metaxas, Dimitris last_name: Metaxas - first_name: Brian full_name: Mirtich, Brian last_name: Mirtich - first_name: David full_name: Mount, David last_name: Mount - first_name: Sankara full_name: Muthukrishnan, Sankara last_name: Muthukrishnan - first_name: Dinesh full_name: Pai, Dinesh last_name: Pai - first_name: Elisha full_name: Sacks, Elisha last_name: Sacks - first_name: Jack full_name: Snoeyink, Jack last_name: Snoeyink - first_name: Subhash full_name: Suri, Subhash last_name: Suri - first_name: Ouri full_name: Wolefson, Ouri last_name: Wolefson citation: ama: Agarwal P, Guibas L, Edelsbrunner H, et al. Algorithmic issues in modeling motion. ACM Computing Surveys. 2002;34(4):550-572. doi:10.1145/592642.592647 apa: Agarwal, P., Guibas, L., Edelsbrunner, H., Erickson, J., Isard, M., Har Peled, S., … Wolefson, O. (2002). Algorithmic issues in modeling motion. ACM Computing Surveys. ACM. https://doi.org/10.1145/592642.592647 chicago: Agarwal, Pankaj, Leonidas Guibas, Herbert Edelsbrunner, Jeff Erickson, Michael Isard, Sariel Har Peled, John Hershberger, et al. “Algorithmic Issues in Modeling Motion.” ACM Computing Surveys. ACM, 2002. https://doi.org/10.1145/592642.592647. ieee: P. Agarwal et al., “Algorithmic issues in modeling motion,” ACM Computing Surveys, vol. 34, no. 4. ACM, pp. 550–572, 2002. ista: Agarwal P, Guibas L, Edelsbrunner H, Erickson J, Isard M, Har Peled S, Hershberger J, Jensen C, Kavraki L, Koehl P, Lin M, Manocha D, Metaxas D, Mirtich B, Mount D, Muthukrishnan S, Pai D, Sacks E, Snoeyink J, Suri S, Wolefson O. 2002. Algorithmic issues in modeling motion. ACM Computing Surveys. 34(4), 550–572. mla: Agarwal, Pankaj, et al. “Algorithmic Issues in Modeling Motion.” ACM Computing Surveys, vol. 34, no. 4, ACM, 2002, pp. 550–72, doi:10.1145/592642.592647. short: P. Agarwal, L. Guibas, H. Edelsbrunner, J. Erickson, M. Isard, S. Har Peled, J. Hershberger, C. Jensen, L. Kavraki, P. Koehl, M. Lin, D. Manocha, D. Metaxas, B. Mirtich, D. Mount, S. Muthukrishnan, D. Pai, E. Sacks, J. Snoeyink, S. Suri, O. Wolefson, ACM Computing Surveys 34 (2002) 550–572. date_created: 2018-12-11T12:06:20Z date_published: 2002-12-01T00:00:00Z date_updated: 2023-06-13T11:34:25Z day: '01' doi: 10.1145/592642.592647 extern: '1' intvolume: ' 34' issue: '4' language: - iso: eng month: '12' oa_version: None page: 550 - 572 publication: ACM Computing Surveys publication_identifier: issn: - 0360-0300 publication_status: published publisher: ACM publist_id: '2129' quality_controlled: '1' scopus_import: '1' status: public title: Algorithmic issues in modeling motion type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 34 year: '2002' ... --- _id: '4000' abstract: - lang: eng text: We present fast implementations of a hybrid algorithm for reporting box and cube intersections. Our algorithm initially takes a divide-and-conquer approach and switches to simpler algorithms for low numbers of boxes. We use our implementations as engines to solve problems about geometric primitives. We look at two such problems in the category of quality analysis of surface triangulations. acknowledgement: Center for Simulation of Advanced Rockets funded by the U.S. Department of Energy under Subcontract B341494, NSF under grant CCR-96-19542 and ARO under grant DAAG55-98-1-0177. article_processing_charge: No article_type: original author: - first_name: Afra full_name: Zomorodian, Afra last_name: Zomorodian - first_name: Herbert full_name: Edelsbrunner, Herbert id: 3FB178DA-F248-11E8-B48F-1D18A9856A87 last_name: Edelsbrunner orcid: 0000-0002-9823-6833 citation: ama: Zomorodian A, Edelsbrunner H. Fast software for box intersections. International Journal of Computational Geometry and Applications. 2002;12(1-2):143-172. doi:10.1142/S0218195902000785 apa: Zomorodian, A., & Edelsbrunner, H. (2002). Fast software for box intersections. International Journal of Computational Geometry and Applications. World Scientific Publishing. https://doi.org/10.1142/S0218195902000785 chicago: Zomorodian, Afra, and Herbert Edelsbrunner. “Fast Software for Box Intersections.” International Journal of Computational Geometry and Applications. World Scientific Publishing, 2002. https://doi.org/10.1142/S0218195902000785. ieee: A. Zomorodian and H. Edelsbrunner, “Fast software for box intersections,” International Journal of Computational Geometry and Applications, vol. 12, no. 1–2. World Scientific Publishing, pp. 143–172, 2002. ista: Zomorodian A, Edelsbrunner H. 2002. Fast software for box intersections. International Journal of Computational Geometry and Applications. 12(1–2), 143–172. mla: Zomorodian, Afra, and Herbert Edelsbrunner. “Fast Software for Box Intersections.” International Journal of Computational Geometry and Applications, vol. 12, no. 1–2, World Scientific Publishing, 2002, pp. 143–72, doi:10.1142/S0218195902000785. short: A. Zomorodian, H. Edelsbrunner, International Journal of Computational Geometry and Applications 12 (2002) 143–172. date_created: 2018-12-11T12:06:22Z date_published: 2002-01-01T00:00:00Z date_updated: 2023-06-13T11:20:09Z day: '01' doi: 10.1142/S0218195902000785 extern: '1' intvolume: ' 12' issue: 1-2 language: - iso: eng month: '01' oa_version: None page: 143 - 172 publication: International Journal of Computational Geometry and Applications publication_identifier: issn: - 0218-1959 publication_status: published publisher: World Scientific Publishing publist_id: '2128' quality_controlled: '1' scopus_import: '1' status: public title: Fast software for box intersections type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 12 year: '2002' ... --- _id: '3998' abstract: - lang: eng text: We present results on a two-step improvement of mesh quality in three-dimensional Delaunay triangulations. The first step refines the triangulation by inserting sinks and eliminates tetrahedra with large circumradius over shortest edge length ratio. The second step assigns weights to the vertices to eliminate slivers. Our experimental findings provide evidence for the practical effectiveness of sliver exudation. acknowledgement: NSF under grants CCR-97-12088 and DMS 98-73945, NSF under grands EIA-9972879 and CCR-00-86013 and by ARO under grant DAAG55-98-1- 0177. article_processing_charge: No article_type: original author: - first_name: Herbert full_name: Edelsbrunner, Herbert id: 3FB178DA-F248-11E8-B48F-1D18A9856A87 last_name: Edelsbrunner orcid: 0000-0002-9823-6833 - first_name: Damrong full_name: Guoy, Damrong last_name: Guoy citation: ama: Edelsbrunner H, Guoy D. An experimental study of sliver exudation. Engineering with Computers. 2002;18(3):229-240. doi:10.1007/s003660200020 apa: Edelsbrunner, H., & Guoy, D. (2002). An experimental study of sliver exudation. Engineering with Computers. Springer. https://doi.org/10.1007/s003660200020 chicago: Edelsbrunner, Herbert, and Damrong Guoy. “An Experimental Study of Sliver Exudation.” Engineering with Computers. Springer, 2002. https://doi.org/10.1007/s003660200020. ieee: H. Edelsbrunner and D. Guoy, “An experimental study of sliver exudation,” Engineering with Computers, vol. 18, no. 3. Springer, pp. 229–240, 2002. ista: Edelsbrunner H, Guoy D. 2002. An experimental study of sliver exudation. Engineering with Computers. 18(3), 229–240. mla: Edelsbrunner, Herbert, and Damrong Guoy. “An Experimental Study of Sliver Exudation.” Engineering with Computers, vol. 18, no. 3, Springer, 2002, pp. 229–40, doi:10.1007/s003660200020. short: H. Edelsbrunner, D. Guoy, Engineering with Computers 18 (2002) 229–240. date_created: 2018-12-11T12:06:21Z date_published: 2002-10-01T00:00:00Z date_updated: 2023-06-13T11:14:44Z day: '01' doi: 10.1007/s003660200020 extern: '1' intvolume: ' 18' issue: '3' language: - iso: eng month: '10' oa_version: None page: 229 - 240 publication: Engineering with Computers publication_identifier: issn: - 0177-0667 publication_status: published publisher: Springer publist_id: '2126' quality_controlled: '1' scopus_import: '1' status: public title: An experimental study of sliver exudation type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 18 year: '2002' ... --- _id: '3802' abstract: - lang: eng text: The presynaptic Ca2+ signal is a key determinant of transmitter release at chemical synapses. In cortical synaptic terminals, however, little is known about the kinetic properties of the presynaptic Ca2+ channels. To investigate the timing and magnitude of the presynaptic Ca2+ inflow, we performed whole-cell patch-clamp recordings from mossy fiber boutons (MFBs) in rat hippocampus. MFBs showed large high-voltage-activated Ca(2+) currents, with a maximal amplitude of approximately 100 pA at a membrane potential of 0 mV. Both activation and deactivation were fast, with time constants in the submillisecond range at a temperature of approximately 23 degrees C. An MFB action potential (AP) applied as a voltage-clamp command evoked a transient Ca2+ current with an average amplitude of approximately 170 pA and a half-duration of 580 microsec. A prepulse to +40 mV had only minimal effects on the AP-evoked Ca2+ current, indicating that presynaptic APs open the voltage-gated Ca2+ channels very effectively. On the basis of the experimental data, we developed a kinetic model with four closed states and one open state, linked by voltage-dependent rate constants. Simulations of the Ca2+ current could reproduce the experimental data, including the large amplitude and rapid time course of the current evoked by MFB APs. Furthermore, the simulations indicate that the shape of the presynaptic AP and the gating kinetics of the Ca2+ channels are tuned to produce a maximal Ca2+ influx during a minimal period of time. The precise timing and high efficacy of Ca2+ channel activation at this cortical glutamatergic synapse may be important for synchronous transmitter release and temporal information processing. acknowledgement: J.B. was supported by grants from the Deutsche Forschungsgemeinschaft (Bi 642/1-2 and SFB 505/C9). We thank Dr. U. Kraushaar, Dr. S. Hefft, and C. Schmidt-Hieber for critically reading this manuscript, F. Heyde for secretarial help, and A. Blomenkamp and K. Winterhalter for technical assistance. article_processing_charge: No article_type: original author: - first_name: Josef full_name: Bischofberger, Josef last_name: Bischofberger - first_name: Jörg full_name: Geiger, Jörg last_name: Geiger - first_name: Peter M full_name: Jonas, Peter M id: 353C1B58-F248-11E8-B48F-1D18A9856A87 last_name: Jonas orcid: 0000-0001-5001-4804 citation: ama: Bischofberger J, Geiger J, Jonas PM. Timing and efficacy of Ca(2+) channel activation in hippocampal mossy fiber boutons. Journal of Neuroscience. 2002;22(24):10593-10602. doi:10.1523/JNEUROSCI.22-24-10593.2002 apa: Bischofberger, J., Geiger, J., & Jonas, P. M. (2002). Timing and efficacy of Ca(2+) channel activation in hippocampal mossy fiber boutons. Journal of Neuroscience. Society for Neuroscience. https://doi.org/10.1523/JNEUROSCI.22-24-10593.2002 chicago: Bischofberger, Josef, Jörg Geiger, and Peter M Jonas. “Timing and Efficacy of Ca(2+) Channel Activation in Hippocampal Mossy Fiber Boutons.” Journal of Neuroscience. Society for Neuroscience, 2002. https://doi.org/10.1523/JNEUROSCI.22-24-10593.2002. ieee: J. Bischofberger, J. Geiger, and P. M. Jonas, “Timing and efficacy of Ca(2+) channel activation in hippocampal mossy fiber boutons,” Journal of Neuroscience, vol. 22, no. 24. Society for Neuroscience, pp. 10593–10602, 2002. ista: Bischofberger J, Geiger J, Jonas PM. 2002. Timing and efficacy of Ca(2+) channel activation in hippocampal mossy fiber boutons. Journal of Neuroscience. 22(24), 10593–10602. mla: Bischofberger, Josef, et al. “Timing and Efficacy of Ca(2+) Channel Activation in Hippocampal Mossy Fiber Boutons.” Journal of Neuroscience, vol. 22, no. 24, Society for Neuroscience, 2002, pp. 10593–602, doi:10.1523/JNEUROSCI.22-24-10593.2002. short: J. Bischofberger, J. Geiger, P.M. Jonas, Journal of Neuroscience 22 (2002) 10593–10602. date_created: 2018-12-11T12:05:15Z date_published: 2002-12-01T00:00:00Z date_updated: 2023-06-13T13:19:45Z day: '01' doi: 10.1523/JNEUROSCI.22-24-10593.2002 extern: '1' external_id: pmid: - '12486151' intvolume: ' 22' issue: '24' language: - iso: eng main_file_link: - open_access: '1' url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6758411/ month: '12' oa: 1 oa_version: Published Version page: 10593 - 10602 pmid: 1 publication: Journal of Neuroscience publication_identifier: issn: - 0270-6474 publication_status: published publisher: Society for Neuroscience publist_id: '2407' quality_controlled: '1' scopus_import: '1' status: public title: Timing and efficacy of Ca(2+) channel activation in hippocampal mossy fiber boutons type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 22 year: '2002' ... --- _id: '3919' abstract: - lang: eng text: Hamilton's concept of local mate competition (LMC) is the standard model to explain female-biased sex ratios in solitary Hymenoptera. In social Hymenoptera, however, LMC has remained controversial, mainly because manipulation of sex allocation by workers in response to relatedness asymmetries is an additional powerful mechanism of female bias. Furthermore, the predominant mating systems in the social insects are thought to make LMC unlikely. Nevertheless, several species exist in which dispersal of males is limited and mating occurs in the nest. Some of these species, such as the ant Cardiocondyla obscurior, have evolved dimorphic males, with one morph being specialized for dispersal and the other for fighting with nest-mate males over access to females. Such life history, combining sociality and alternative reproductive tactics in males, provides a unique opportunity to test the power of LMC as a selective force leading to female-biased sex ratios in social Hymenoptera. We show that, in concordance with LMC predictions, an experimental increase in queen number leads to a shift in sex allocation in favour of non-dispersing males, but does not influence the proportion of disperser males. Furthermore, we can assign this change in sex allocation at the colony level to the queens and rule out worker manipulation. acknowledgement: 'We thank A. F. G. Bourke, J. J. Boomsma, S. Foitzik, M. Sixt,C. Anderson and C. Schubart for improving the manuscript, and E. Sixt for ant illustrations (figure 2). This study was funded by the DFG (Deutsche Forschungsgemeinschaft: He1623/7-2).' article_processing_charge: No article_type: original author: - first_name: Sylvia full_name: Cremer, Sylvia id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87 last_name: Cremer orcid: 0000-0002-2193-3868 - first_name: Jürgen full_name: Heinze, Jürgen last_name: Heinze citation: ama: 'Cremer S, Heinze J. Adaptive production of fighter males: queens of the ant Cardiocondyla adjust the sex ratio under local mate competition. Proceedings of the Royal Society of London Series B Biological Sciences. 2002;269(1489):417-422. doi:10.1098/rspb.2001.1892' apa: 'Cremer, S., & Heinze, J. (2002). Adaptive production of fighter males: queens of the ant Cardiocondyla adjust the sex ratio under local mate competition. Proceedings of the Royal Society of London Series B Biological Sciences. Royal Society, The. https://doi.org/10.1098/rspb.2001.1892' chicago: 'Cremer, Sylvia, and Jürgen Heinze. “Adaptive Production of Fighter Males: Queens of the Ant Cardiocondyla Adjust the Sex Ratio under Local Mate Competition.” Proceedings of the Royal Society of London Series B Biological Sciences. Royal Society, The, 2002. https://doi.org/10.1098/rspb.2001.1892.' ieee: 'S. Cremer and J. Heinze, “Adaptive production of fighter males: queens of the ant Cardiocondyla adjust the sex ratio under local mate competition,” Proceedings of the Royal Society of London Series B Biological Sciences, vol. 269, no. 1489. Royal Society, The, pp. 417–422, 2002.' ista: 'Cremer S, Heinze J. 2002. Adaptive production of fighter males: queens of the ant Cardiocondyla adjust the sex ratio under local mate competition. Proceedings of the Royal Society of London Series B Biological Sciences. 269(1489), 417–422.' mla: 'Cremer, Sylvia, and Jürgen Heinze. “Adaptive Production of Fighter Males: Queens of the Ant Cardiocondyla Adjust the Sex Ratio under Local Mate Competition.” Proceedings of the Royal Society of London Series B Biological Sciences, vol. 269, no. 1489, Royal Society, The, 2002, pp. 417–22, doi:10.1098/rspb.2001.1892.' short: S. Cremer, J. Heinze, Proceedings of the Royal Society of London Series B Biological Sciences 269 (2002) 417–422. date_created: 2018-12-11T12:05:53Z date_published: 2002-02-22T00:00:00Z date_updated: 2023-06-13T11:52:17Z day: '22' doi: 10.1098/rspb.2001.1892 extern: '1' external_id: pmid: - '11886631' intvolume: ' 269' issue: '1489' language: - iso: eng main_file_link: - open_access: '1' url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1690910/ month: '02' oa: 1 oa_version: None page: 417 - 422 pmid: 1 publication: Proceedings of the Royal Society of London Series B Biological Sciences publication_identifier: issn: - 0962-8452 publication_status: published publisher: Royal Society, The publist_id: '2231' quality_controlled: '1' scopus_import: '1' status: public title: 'Adaptive production of fighter males: queens of the ant Cardiocondyla adjust the sex ratio under local mate competition' type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 269 year: '2002' ... --- _id: '3924' abstract: - lang: eng text: 'Males of the ant Cardiocondyla show a dispersal dimorphism of a winged and wingless morph. The loss of flight has lead to morphological reductions in the wingless (ergatoid) males and also affected body size, eye size and pigmentation. As ergatoid males mate exclusively inside the maternal nest, they underlie increased male-male competition and therefore have also evolved additional changes in behaviour and physiology: in contrast to winged males, ergatoid males are highly aggressive towards each other and their spermatogenesis is prolonged compared to all other hymenopteran males. In addition to these two male morphs, we found males with an intermediate appearance. These "intermorphic" males provide a transitional stage between normal males in most investigated morphological and physiological parameters. As they are produced extremely rarely and only in colonies that switch between pure ergatoid to mixed male production, we argue that they likely represent a developmental mistake. Parallels between the determination of male morphs and female castes (queen-worker dimorphism and worker polymorphism) might help to understand how the large potential of phenotypic plasticity in both sexes of social insects is realised during development.' acknowledgement: We would like to thank S. Karpeles for histological analysis of the winged males and S. Buchhauser for help with the photographs. This study was funded by the DFG (grant He1623/12–1). article_processing_charge: No article_type: original author: - first_name: Sylvia full_name: Cremer, Sylvia id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87 last_name: Cremer orcid: 0000-0002-2193-3868 - first_name: Birgit full_name: Lautenschläger, Birgit last_name: Lautenschläger - first_name: Jürgen full_name: Heinze, Jürgen last_name: Heinze citation: ama: Cremer S, Lautenschläger B, Heinze J. A transitional stage between the ergatoid and winged male morph in the ant Cardiocondyla obscurior. Insectes Sociaux. 2002;49(3):221-228. doi:10.1007/s00040-002-8305-z apa: Cremer, S., Lautenschläger, B., & Heinze, J. (2002). A transitional stage between the ergatoid and winged male morph in the ant Cardiocondyla obscurior. Insectes Sociaux. Springer. https://doi.org/10.1007/s00040-002-8305-z chicago: Cremer, Sylvia, Birgit Lautenschläger, and Jürgen Heinze. “A Transitional Stage between the Ergatoid and Winged Male Morph in the Ant Cardiocondyla Obscurior.” Insectes Sociaux. Springer, 2002. https://doi.org/10.1007/s00040-002-8305-z. ieee: S. Cremer, B. Lautenschläger, and J. Heinze, “A transitional stage between the ergatoid and winged male morph in the ant Cardiocondyla obscurior,” Insectes Sociaux, vol. 49, no. 3. Springer, pp. 221–228, 2002. ista: Cremer S, Lautenschläger B, Heinze J. 2002. A transitional stage between the ergatoid and winged male morph in the ant Cardiocondyla obscurior. Insectes Sociaux. 49(3), 221–228. mla: Cremer, Sylvia, et al. “A Transitional Stage between the Ergatoid and Winged Male Morph in the Ant Cardiocondyla Obscurior.” Insectes Sociaux, vol. 49, no. 3, Springer, 2002, pp. 221–28, doi:10.1007/s00040-002-8305-z. short: S. Cremer, B. Lautenschläger, J. Heinze, Insectes Sociaux 49 (2002) 221–228. date_created: 2018-12-11T12:05:55Z date_published: 2002-04-05T00:00:00Z date_updated: 2023-06-13T11:44:08Z day: '05' doi: 10.1007/s00040-002-8305-z extern: '1' intvolume: ' 49' issue: '3' language: - iso: eng month: '04' oa_version: None page: 221 - 228 publication: Insectes Sociaux publication_identifier: issn: - 0020-1812 publication_status: published publisher: Springer publist_id: '2229' quality_controlled: '1' scopus_import: '1' status: public title: A transitional stage between the ergatoid and winged male morph in the ant Cardiocondyla obscurior type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 49 year: '2002' ... --- _id: '3925' abstract: - lang: eng text: Males of the tropical ant Cardiocondyla obscurior are either wingless and aggressive or winged and docile, and both compete for access to virgin queens in the nest1, 2. Although the fighter males (ergatoids) attack and kill other ergatoids, they tolerate and even attempt to mate with their winged rivals. Here we show that the winged males avoid the aggression of wingless males by mimicking the chemical bouquet of virgin queens, but that their mating success is not reduced as a result. This example of female mimicry by vigorous males is surprising, as in other species it is typically used as a protective strategy by weaker males, and may explain the coexistence and equal mating success of two male morphs. article_processing_charge: No article_type: original author: - first_name: Sylvia full_name: Cremer, Sylvia id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87 last_name: Cremer orcid: 0000-0002-2193-3868 - first_name: Matthew full_name: Sledge, Matthew last_name: Sledge - first_name: Jürgen full_name: Heinze, Jürgen last_name: Heinze citation: ama: 'Cremer S, Sledge M, Heinze J. Chemical mimicry: Male ants disguised by the queen’s bouquet. Nature. 2002;419:897-897. doi:10.1038/419897a' apa: 'Cremer, S., Sledge, M., & Heinze, J. (2002). Chemical mimicry: Male ants disguised by the queen’s bouquet. Nature. Nature Publishing Group. https://doi.org/10.1038/419897a' chicago: 'Cremer, Sylvia, Matthew Sledge, and Jürgen Heinze. “Chemical Mimicry: Male Ants Disguised by the Queen’s Bouquet.” Nature. Nature Publishing Group, 2002. https://doi.org/10.1038/419897a.' ieee: 'S. Cremer, M. Sledge, and J. Heinze, “Chemical mimicry: Male ants disguised by the queen’s bouquet,” Nature, vol. 419. Nature Publishing Group, pp. 897–897, 2002.' ista: 'Cremer S, Sledge M, Heinze J. 2002. Chemical mimicry: Male ants disguised by the queen’s bouquet. Nature. 419, 897–897.' mla: 'Cremer, Sylvia, et al. “Chemical Mimicry: Male Ants Disguised by the Queen’s Bouquet.” Nature, vol. 419, Nature Publishing Group, 2002, pp. 897–897, doi:10.1038/419897a.' short: S. Cremer, M. Sledge, J. Heinze, Nature 419 (2002) 897–897. date_created: 2018-12-11T12:05:55Z date_published: 2002-10-31T00:00:00Z date_updated: 2023-06-13T11:47:19Z day: '31' doi: 10.1038/419897a extern: '1' external_id: pmid: - '12410300' intvolume: ' 419' language: - iso: eng month: '10' oa_version: None page: 897 - 897 pmid: 1 publication: Nature publication_identifier: issn: - 0028-0836 publication_status: published publisher: Nature Publishing Group publist_id: '2230' quality_controlled: '1' scopus_import: '1' status: public title: 'Chemical mimicry: Male ants disguised by the queen''s bouquet' type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 419 year: '2002' ... --- _id: '3996' abstract: - lang: eng text: We formalize a notion of topological simplification within the framework of a filtration, which is the history of a growing complex. We classify a topological change that happens during growth as either a feature or noise depending on its lifetime or persistence within the filtration. We give fast algorithms for computing persistence and experimental evidence for their speed and utility. acknowledgement: "We thank Jeff Erickson and John Harer for helpful discussions during early stages of this\r\npaper. We also thank Daniel Huson for the zeolite dataset Z, Thomas LaBean for the DNA\r\ndataset D, and the Stanford Graphics Lab for the Buddha dataset S. To generate the bone\r\ndataset B, we sampled an iso-surface generated by Dominique Attali. The volume data\r\nTopological Persistence and Simplification 533 was provided by Francoise Peyrin from CNRS CREATIS in Lyon and was issued from ¸ Synchrotron Radiation Microtomography from the ID19 beamline at ESRF in Grenoble.\r\nWe generated Fig. 17 using the Protein Explorer [6]." article_processing_charge: No article_type: original author: - first_name: Herbert full_name: Edelsbrunner, Herbert id: 3FB178DA-F248-11E8-B48F-1D18A9856A87 last_name: Edelsbrunner orcid: 0000-0002-9823-6833 - first_name: David full_name: Letscher, David last_name: Letscher - first_name: Afra full_name: Zomorodian, Afra last_name: Zomorodian citation: ama: Edelsbrunner H, Letscher D, Zomorodian A. Topological persistence and simplification. Discrete & Computational Geometry. 2002;28(4):511-533. doi:10.1007/s00454-002-2885-2 apa: Edelsbrunner, H., Letscher, D., & Zomorodian, A. (2002). Topological persistence and simplification. Discrete & Computational Geometry. Springer. https://doi.org/10.1007/s00454-002-2885-2 chicago: Edelsbrunner, Herbert, David Letscher, and Afra Zomorodian. “Topological Persistence and Simplification.” Discrete & Computational Geometry. Springer, 2002. https://doi.org/10.1007/s00454-002-2885-2. ieee: H. Edelsbrunner, D. Letscher, and A. Zomorodian, “Topological persistence and simplification,” Discrete & Computational Geometry, vol. 28, no. 4. Springer, pp. 511–533, 2002. ista: Edelsbrunner H, Letscher D, Zomorodian A. 2002. Topological persistence and simplification. Discrete & Computational Geometry. 28(4), 511–533. mla: Edelsbrunner, Herbert, et al. “Topological Persistence and Simplification.” Discrete & Computational Geometry, vol. 28, no. 4, Springer, 2002, pp. 511–33, doi:10.1007/s00454-002-2885-2. short: H. Edelsbrunner, D. Letscher, A. Zomorodian, Discrete & Computational Geometry 28 (2002) 511–533. date_created: 2018-12-11T12:06:20Z date_published: 2002-12-01T00:00:00Z date_updated: 2023-06-13T11:41:19Z day: '01' doi: 10.1007/s00454-002-2885-2 extern: '1' intvolume: ' 28' issue: '4' language: - iso: eng month: '12' oa_version: None page: 511 - 533 publication: Discrete & Computational Geometry publication_identifier: issn: - 0179-5376 publication_status: published publisher: Springer publist_id: '2130' quality_controlled: '1' scopus_import: '1' status: public title: Topological persistence and simplification type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 28 year: '2002' ... --- _id: '3920' abstract: - lang: eng text: A particular Solid Injector needle, suitable for GC-MS analyses of small specimens, is described together with its application in a study on ants. acknowledgement: "We thank Giancarlo Bucelli and Gloriano Moneti (Centro Interdipartimentale\r\ndi Spettrometria di Massa, Università di Firenze) for their help. Funding was\r\nprovided by the MURST “60%” and Italian CNR “40%” funds, as well as through\r\nthe research network “Social evolution” of the Universities of Aarhus, Firenze,\r\nKeele, Sheffield, Uppsala, Würzburg and the ETH of Zürich financed by the\r\nEuropean commission via the Training and Mobility of Researchers (TMR)\r\nprogramme. " article_processing_charge: No article_type: original author: - first_name: Stefano full_name: Turillazzi, Stefano last_name: Turillazzi - first_name: Matthew full_name: Sledge, Matthew last_name: Sledge - first_name: Sylvia full_name: Cremer, Sylvia id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87 last_name: Cremer orcid: 0000-0002-2193-3868 - first_name: Jürgen full_name: Heinze, Jürgen last_name: Heinze citation: ama: Turillazzi S, Sledge M, Cremer S, Heinze J. A method for analysing small-size specimens in GC-MS. Insect Social Life. 2002;4:169-175. apa: Turillazzi, S., Sledge, M., Cremer, S., & Heinze, J. (2002). A method for analysing small-size specimens in GC-MS. Insect Social Life. Elsevier. chicago: Turillazzi, Stefano, Matthew Sledge, Sylvia Cremer, and Jürgen Heinze. “A Method for Analysing Small-Size Specimens in GC-MS.” Insect Social Life. Elsevier, 2002. ieee: S. Turillazzi, M. Sledge, S. Cremer, and J. Heinze, “A method for analysing small-size specimens in GC-MS,” Insect Social Life, vol. 4. Elsevier, pp. 169–175, 2002. ista: Turillazzi S, Sledge M, Cremer S, Heinze J. 2002. A method for analysing small-size specimens in GC-MS. Insect Social Life. 4, 169–175. mla: Turillazzi, Stefano, et al. “A Method for Analysing Small-Size Specimens in GC-MS.” Insect Social Life, vol. 4, Elsevier, 2002, pp. 169–75. short: S. Turillazzi, M. Sledge, S. Cremer, J. Heinze, Insect Social Life 4 (2002) 169–175. date_created: 2018-12-11T12:05:54Z date_published: 2002-01-01T00:00:00Z date_updated: 2023-06-13T12:57:06Z day: '01' extern: '1' intvolume: ' 4' language: - iso: eng month: '01' oa_version: None page: 169 - 175 publication: Insect Social Life publication_status: published publisher: Elsevier publist_id: '2232' quality_controlled: '1' status: public title: A method for analysing small-size specimens in GC-MS type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 4 year: '2002' ... --- _id: '3800' abstract: - lang: eng text: Networks of GABAergic interneurons are of critical importance for the generation of gamma frequency oscillations in the brain. To examine the underlying synaptic mechanisms, we made paired recordings from "basket cells" (BCs) in different subfields of hippocampal slices, using transgenic mice that express enhanced green fluorescent protein (EGFP) under the control of the parvalbumin promoter. Unitary inhibitory postsynaptic currents (IPSCs) showed large amplitude and fast time course with mean amplitude-weighted decay time constants of 2.5, 1.2, and 1.8 ms in the dentate gyrus, and the cornu ammonis area 3 (CA3) and 1 (CA1), respectively (33-34 degrees C). The decay of unitary IPSCs at BC-BC synapses was significantly faster than that at BC-principal cell synapses, indicating target cell-specific differences in IPSC kinetics. In addition, electrical coupling was found in a subset of BC-BC pairs. To examine whether an interneuron network with fast inhibitory synapses can act as a gamma frequency oscillator, we developed an interneuron network model based on experimentally determined properties. In comparison to previous interneuron network models, our model was able to generate oscillatory activity with higher coherence over a broad range of frequencies (20-110 Hz). In this model, high coherence and flexibility in frequency control emerge from the combination of synaptic properties, network structure, and electrical coupling. acknowledgement: We thank Drs. J. Bischofberger, M. Heckmann, and R. Traub for critically reading the manuscript. This work was supported by Deutsche Forschungsgemeinschaft Grants SFB 505/C5 (to P.J.) and SFB 505/C6 (to M.F. and P.J.), Human Frontiers Science Program Organization Grant RG0017/1998-B (to P.J.), and grants from the Alexander-von-Humboldt Foundation (to P.J. and M.F.), the Schilling Foundation (to H.M.), and Novartis (to H.M.). article_processing_charge: No article_type: original author: - first_name: Marlene full_name: Bartos, Marlene last_name: Bartos - first_name: Imre full_name: Vida, Imre last_name: Vida - first_name: Michael full_name: Frotscher, Michael last_name: Frotscher - first_name: Axel full_name: Meyer, Axel last_name: Meyer - first_name: Hannah full_name: Monyer, Hannah last_name: Monyer - first_name: Jörg full_name: Geiger, Jörg last_name: Geiger - first_name: Peter M full_name: Jonas, Peter M id: 353C1B58-F248-11E8-B48F-1D18A9856A87 last_name: Jonas orcid: 0000-0001-5001-4804 citation: ama: Bartos M, Vida I, Frotscher M, et al. Fast synaptic inhibition promotes synchronized gamma oscillations in hippocampal interneuron networks. PNAS. 2002;99(20):13222-13227. doi:10.1073/pnas.192233099 apa: Bartos, M., Vida, I., Frotscher, M., Meyer, A., Monyer, H., Geiger, J., & Jonas, P. M. (2002). Fast synaptic inhibition promotes synchronized gamma oscillations in hippocampal interneuron networks. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.192233099 chicago: Bartos, Marlene, Imre Vida, Michael Frotscher, Axel Meyer, Hannah Monyer, Jörg Geiger, and Peter M Jonas. “Fast Synaptic Inhibition Promotes Synchronized Gamma Oscillations in Hippocampal Interneuron Networks.” PNAS. National Academy of Sciences, 2002. https://doi.org/10.1073/pnas.192233099. ieee: M. Bartos et al., “Fast synaptic inhibition promotes synchronized gamma oscillations in hippocampal interneuron networks,” PNAS, vol. 99, no. 20. National Academy of Sciences, pp. 13222–13227, 2002. ista: Bartos M, Vida I, Frotscher M, Meyer A, Monyer H, Geiger J, Jonas PM. 2002. Fast synaptic inhibition promotes synchronized gamma oscillations in hippocampal interneuron networks. PNAS. 99(20), 13222–13227. mla: Bartos, Marlene, et al. “Fast Synaptic Inhibition Promotes Synchronized Gamma Oscillations in Hippocampal Interneuron Networks.” PNAS, vol. 99, no. 20, National Academy of Sciences, 2002, pp. 13222–27, doi:10.1073/pnas.192233099. short: M. Bartos, I. Vida, M. Frotscher, A. Meyer, H. Monyer, J. Geiger, P.M. Jonas, PNAS 99 (2002) 13222–13227. date_created: 2018-12-11T12:05:14Z date_published: 2002-09-16T00:00:00Z date_updated: 2023-07-10T13:35:18Z day: '16' doi: 10.1073/pnas.192233099 extern: '1' external_id: pmid: - '12235359' intvolume: ' 99' issue: '20' language: - iso: eng main_file_link: - open_access: '1' url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC130614/ month: '09' oa: 1 oa_version: Published Version page: 13222 - 13227 pmid: 1 publication: PNAS publication_identifier: issn: - 0027-8424 publication_status: published publisher: National Academy of Sciences publist_id: '2409' quality_controlled: '1' scopus_import: '1' status: public title: Fast synaptic inhibition promotes synchronized gamma oscillations in hippocampal interneuron networks type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 99 year: '2002' ... --- _id: '3803' abstract: - lang: eng text: Mossy fiber (MF) synapses are key stations for flow of information through the hippocampal formation. A major component of the output of the MF system is directed towards inhibitory interneurons. Recent studies have revealed that the functional properties of MF-interneuron synapses differ substantially from those of MF-CA3 pyramidal neuron synapses. Mossy-fiber-interneuron synapses in the stratum lucidum represent a continuum of functional subtypes, in which the subunit composition of postsynaptic AMPA receptors and NMDA receptors appears to be regulated in a coordinated manner. article_processing_charge: No article_type: letter_note author: - first_name: Josef full_name: Bischofberger, Josef last_name: Bischofberger - first_name: Peter M full_name: Jonas, Peter M id: 353C1B58-F248-11E8-B48F-1D18A9856A87 last_name: Jonas orcid: 0000-0001-5001-4804 citation: ama: 'Bischofberger J, Jonas PM. TwoB or not twoB: differential transmission at glutamatergic mossy fiber-interneuron synapses in the hippocampus. Trends in Neurosciences. 2002;25(12):600-603. doi:10.1016/S0166-2236(02)02259-2' apa: 'Bischofberger, J., & Jonas, P. M. (2002). TwoB or not twoB: differential transmission at glutamatergic mossy fiber-interneuron synapses in the hippocampus. Trends in Neurosciences. Elsevier. https://doi.org/10.1016/S0166-2236(02)02259-2' chicago: 'Bischofberger, Josef, and Peter M Jonas. “TwoB or Not TwoB: Differential Transmission at Glutamatergic Mossy Fiber-Interneuron Synapses in the Hippocampus.” Trends in Neurosciences. Elsevier, 2002. https://doi.org/10.1016/S0166-2236(02)02259-2.' ieee: 'J. Bischofberger and P. M. Jonas, “TwoB or not twoB: differential transmission at glutamatergic mossy fiber-interneuron synapses in the hippocampus,” Trends in Neurosciences, vol. 25, no. 12. Elsevier, pp. 600–603, 2002.' ista: 'Bischofberger J, Jonas PM. 2002. TwoB or not twoB: differential transmission at glutamatergic mossy fiber-interneuron synapses in the hippocampus. Trends in Neurosciences. 25(12), 600–603.' mla: 'Bischofberger, Josef, and Peter M. Jonas. “TwoB or Not TwoB: Differential Transmission at Glutamatergic Mossy Fiber-Interneuron Synapses in the Hippocampus.” Trends in Neurosciences, vol. 25, no. 12, Elsevier, 2002, pp. 600–03, doi:10.1016/S0166-2236(02)02259-2.' short: J. Bischofberger, P.M. Jonas, Trends in Neurosciences 25 (2002) 600–603. date_created: 2018-12-11T12:05:15Z date_published: 2002-12-01T00:00:00Z date_updated: 2023-07-10T13:22:24Z day: '01' doi: 10.1016/S0166-2236(02)02259-2 extern: '1' external_id: pmid: - '12446120' intvolume: ' 25' issue: '12' language: - iso: eng month: '12' oa_version: None page: 600 - 603 pmid: 1 publication: Trends in Neurosciences publication_identifier: issn: - 0166-2236 publication_status: published publisher: Elsevier publist_id: '2408' quality_controlled: '1' status: public title: 'TwoB or not twoB: differential transmission at glutamatergic mossy fiber-interneuron synapses in the hippocampus' type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 25 year: '2002' ... --- _id: '3801' abstract: - lang: eng text: 'To examine possible interactions between fast depression and modulation of inhibitory synaptic transmission in the hippocampus, we recorded from pairs of synaptically connected basket cells (BCs) and granule cells (GCs) in the dentate gyrus of rat brain slices at 34 degrees C. Multiple-pulse depression (MPD) was examined in trains of 5 or 10 inhibitory postsynaptic currents (IPSCs) evoked at frequencies of 10-100 Hz under several conditions that inhibit transmitter release: block of voltage-dependent Ca2+ channels by Cd2+ (10 microM), activation of gamma-amino-butyric acid type B receptors (GABA(B)Rs) by baclofen (10 microM) and activation of muscarinic acetylcholine receptors (mAchRs) by carbachol (2 microM). All manipulations led to a substantial inhibition of synaptic transmission, reducing the amplitude of the first IPSC in the train (IPSC1) by 72%, 61% and 29%, respectively. However, MPD was largely preserved under these conditions (0.34 in control versus 0.31, 0.50 and 0.47 in the respective conditions at 50 Hz). Similarly, a theta burst stimulation (TBS) protocol reduced IPSC1 by 54%, but left MPD unchanged (0.40 in control and 0.39 during TBS). Analysis of both fractions of transmission failures and coefficients of variation (CV) of IPSC peak amplitudes suggested that MPD had a presynaptic expression site, independent of release probability. In conclusion, different types of presynaptic modulation of inhibitory synaptic transmission converge on a reduction of synaptic strength, while short-term dynamics are largely unchanged.' acknowledgement: We thank Drs M. Bartos, J. Bischofberger, M. Heckmann and I. Vida for critically reading the manuscript, Dr K. Götz for providing information about pharmacological properties of inhibitory hippocampal synapses, and A. Blomenkamp and K. Winterhalter for technical assistance. This work was supported by Deutsche Forschungsgemeinschaft grants to P.J. (Jo-248/2-2,SFB 505/C5) and the Alexander-von-Humboldt foundation. article_processing_charge: No article_type: original author: - first_name: Stefan full_name: Hefft, Stefan last_name: Hefft - first_name: Udo full_name: Kraushaar, Udo last_name: Kraushaar - first_name: Jörg full_name: Geiger, Jörg last_name: Geiger - first_name: Peter M full_name: Jonas, Peter M id: 353C1B58-F248-11E8-B48F-1D18A9856A87 last_name: Jonas orcid: 0000-0001-5001-4804 citation: ama: Hefft S, Kraushaar U, Geiger J, Jonas PM. Presynaptic short-term depression is maintained during regulation of transmitter release at a GABAergic synapse in rat hippocampus. Journal of Physiology. 2002;539(Pt 1):201-208. doi:10.1113/jphysiol.2001.013455 apa: Hefft, S., Kraushaar, U., Geiger, J., & Jonas, P. M. (2002). Presynaptic short-term depression is maintained during regulation of transmitter release at a GABAergic synapse in rat hippocampus. Journal of Physiology. Wiley-Blackwell. https://doi.org/10.1113/jphysiol.2001.013455 chicago: Hefft, Stefan, Udo Kraushaar, Jörg Geiger, and Peter M Jonas. “Presynaptic Short-Term Depression Is Maintained during Regulation of Transmitter Release at a GABAergic Synapse in Rat Hippocampus.” Journal of Physiology. Wiley-Blackwell, 2002. https://doi.org/10.1113/jphysiol.2001.013455. ieee: S. Hefft, U. Kraushaar, J. Geiger, and P. M. Jonas, “Presynaptic short-term depression is maintained during regulation of transmitter release at a GABAergic synapse in rat hippocampus,” Journal of Physiology, vol. 539, no. Pt 1. Wiley-Blackwell, pp. 201–8, 2002. ista: Hefft S, Kraushaar U, Geiger J, Jonas PM. 2002. Presynaptic short-term depression is maintained during regulation of transmitter release at a GABAergic synapse in rat hippocampus. Journal of Physiology. 539(Pt 1), 201–8. mla: Hefft, Stefan, et al. “Presynaptic Short-Term Depression Is Maintained during Regulation of Transmitter Release at a GABAergic Synapse in Rat Hippocampus.” Journal of Physiology, vol. 539, no. Pt 1, Wiley-Blackwell, 2002, pp. 201–08, doi:10.1113/jphysiol.2001.013455. short: S. Hefft, U. Kraushaar, J. Geiger, P.M. Jonas, Journal of Physiology 539 (2002) 201–8. date_created: 2018-12-11T12:05:15Z date_published: 2002-02-01T00:00:00Z date_updated: 2023-07-11T10:01:12Z day: '01' doi: 10.1113/jphysiol.2001.013455 extern: '1' external_id: pmid: - '11850513' intvolume: ' 539' issue: Pt 1 language: - iso: eng main_file_link: - open_access: '1' url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290140/ month: '02' oa: 1 oa_version: Published Version page: 201 - 8 pmid: 1 publication: Journal of Physiology publication_identifier: issn: - 0022-3751 publication_status: published publisher: Wiley-Blackwell publist_id: '2410' quality_controlled: '1' scopus_import: '1' status: public title: Presynaptic short-term depression is maintained during regulation of transmitter release at a GABAergic synapse in rat hippocampus type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 539 year: '2002' ... --- _id: '3799' abstract: - lang: eng text: 'GABAergic interneurones are diverse in their morphological and functional properties. Perisomatic inhibitory cells show fast spiking during sustained current injection, whereas dendritic inhibitory cells fire action potentials with lower frequency. We examined functional and molecular properties of K(+) channels in interneurones with horizontal dendrites in stratum oriens-alveus (OA) of the hippocampal CA1 region, which mainly comprise somatostatin-positive dendritic inhibitory cells. Voltage-gated K(+) currents in nucleated patches isolated from OA interneurones consisted of three major components: a fast delayed rectifier K(+) current component that was highly sensitive to external 4-aminopyridine (4-AP) and tetraethylammonium (TEA) (half-maximal inhibitory concentrations < 0.1 mM for both blockers), a slow delayed rectifier K(+) current component that was sensitive to high concentrations of TEA, but insensitive to 4-AP, and a rapidly inactivating A-type K(+) current component that was blocked by high concentrations of 4-AP, but resistant to TEA. The relative contributions of these components to the macroscopic K(+) current were estimated as 57 +/- 5, 25 +/- 6, and 19 +/- 2 %, respectively. Dendrotoxin, a selective blocker of Kv1 channels had only minimal effects on K(+) currents in nucleated patches. Coapplication of the membrane-permeant cAMP analogue 8-(4-chlorophenylthio)-adenosine 3'':5''-cyclic monophosphate (cpt-cAMP) and the phosphodiesterase blocker isobutyl-methylxanthine (IBMX) resulted in a selective inhibition of the fast delayed rectifier K(+) current component. This inhibition was absent in the presence of the protein kinase A (PKA) inhibitor H-89, implying the involvement of PKA-mediated phosphorylation. Single-cell reverse transcription-polymerase chain reaction (RT-PCR) analysis revealed a high abundance of Kv3.2 mRNA in OA interneurones, whereas the expression level of Kv3.1 mRNA was markedly lower. Similarly, RT-PCR analysis showed a high abundance of Kv4.3 mRNA, whereas Kv4.2 mRNA was undetectable. This suggests that the fast delayed rectifier K(+) current and the A-type K(+) current component are mediated predominantly by homomeric Kv3.2 and Kv4.3 channels. Selective modulation of Kv3.2 channels in OA interneurones by cAMP is likely to be an important factor regulating the activity of dendritic inhibitory cells in principal neurone-interneurone microcircuits.' acknowledgement: We thank Drs J. Bischofberger, M. Heckmann, and I. Vida for critically reading the manuscript, and A. Blomenkamp and K. Winterhalter for technical assistance. This work was supported by a scholarship from the Deutscher Akademischer Austansch dienst to C.-C. L., a Deutsche Forschungsgemeinschaft grant to P. J. (SFB 505/C5), and the Alexander-von-Humboldt foundation. article_processing_charge: No article_type: original author: - first_name: Cheng full_name: Lien, Cheng last_name: Lien - first_name: Marco full_name: Martina, Marco last_name: Martina - first_name: Jobst full_name: Schultz, Jobst last_name: Schultz - first_name: Heimo full_name: Ehmke, Heimo last_name: Ehmke - first_name: Peter M full_name: Jonas, Peter M id: 353C1B58-F248-11E8-B48F-1D18A9856A87 last_name: Jonas orcid: 0000-0001-5001-4804 citation: ama: Lien C, Martina M, Schultz J, Ehmke H, Jonas PM. Gating, modulation and subunit composition of voltage-gated K(+) channels in dendritic inhibitory interneurones of rat hippocampus. Journal of Physiology. 2002;538(Pt 2):405-419. doi:10.1113/jphysiol.2001.013066 apa: Lien, C., Martina, M., Schultz, J., Ehmke, H., & Jonas, P. M. (2002). Gating, modulation and subunit composition of voltage-gated K(+) channels in dendritic inhibitory interneurones of rat hippocampus. Journal of Physiology. Wiley-Blackwell. https://doi.org/10.1113/jphysiol.2001.013066 chicago: Lien, Cheng, Marco Martina, Jobst Schultz, Heimo Ehmke, and Peter M Jonas. “Gating, Modulation and Subunit Composition of Voltage-Gated K(+) Channels in Dendritic Inhibitory Interneurones of Rat Hippocampus.” Journal of Physiology. Wiley-Blackwell, 2002. https://doi.org/10.1113/jphysiol.2001.013066. ieee: C. Lien, M. Martina, J. Schultz, H. Ehmke, and P. M. Jonas, “Gating, modulation and subunit composition of voltage-gated K(+) channels in dendritic inhibitory interneurones of rat hippocampus,” Journal of Physiology, vol. 538, no. Pt 2. Wiley-Blackwell, pp. 405–419, 2002. ista: Lien C, Martina M, Schultz J, Ehmke H, Jonas PM. 2002. Gating, modulation and subunit composition of voltage-gated K(+) channels in dendritic inhibitory interneurones of rat hippocampus. Journal of Physiology. 538(Pt 2), 405–419. mla: Lien, Cheng, et al. “Gating, Modulation and Subunit Composition of Voltage-Gated K(+) Channels in Dendritic Inhibitory Interneurones of Rat Hippocampus.” Journal of Physiology, vol. 538, no. Pt 2, Wiley-Blackwell, 2002, pp. 405–19, doi:10.1113/jphysiol.2001.013066. short: C. Lien, M. Martina, J. Schultz, H. Ehmke, P.M. Jonas, Journal of Physiology 538 (2002) 405–419. date_created: 2018-12-11T12:05:14Z date_published: 2002-01-01T00:00:00Z date_updated: 2023-07-11T12:32:26Z day: '01' doi: 10.1113/jphysiol.2001.013066 extern: '1' external_id: pmid: - '11790809' intvolume: ' 538' issue: Pt 2 language: - iso: eng main_file_link: - open_access: '1' url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290075/ month: '01' oa: 1 oa_version: Published Version page: 405 - 419 pmid: 1 publication: Journal of Physiology publication_identifier: issn: - 0022-3751 publication_status: published publisher: Wiley-Blackwell publist_id: '2411' quality_controlled: '1' status: public title: Gating, modulation and subunit composition of voltage-gated K(+) channels in dendritic inhibitory interneurones of rat hippocampus type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 538 year: '2002' ... --- _id: '3621' abstract: - lang: eng text: In 1991, Barton and Turelli developed recursions to describe the evolution of multilocus systems under arbitrary forms of selection. This article generalizes their approach to allow for arbitrary modes of inheritance, including diploidy, polyploidy, sex linkage, cytoplasmic inheritance, and genomic imprinting. The framework is also extended to allow for other deterministic evolutionary forces, including migration and mutation. Exact recursions that fully describe the state of the population are presented; these are implemented in a computer algebra package (available on the Web at http://helios.bto.ed.ac.uk/evolgen). Despite the generality of our framework, it can describe evolutionary dynamics exactly by just two equations. These recursions can be further simplified using a "quasi-linkage equilibrium" (QLE) approximation. We illustrate the methods by finding the effect of natural selection, sexual selection, mutation, and migration on the genetic composition of a population. article_processing_charge: No article_type: original author: - first_name: Mark full_name: Kirkpatrick, Mark last_name: Kirkpatrick - first_name: Toby full_name: Johnson, Toby last_name: Johnson - first_name: Nicholas H full_name: Barton, Nicholas H id: 4880FE40-F248-11E8-B48F-1D18A9856A87 last_name: Barton orcid: 0000-0002-8548-5240 citation: ama: Kirkpatrick M, Johnson T, Barton NH. General models of multilocus evolution. Genetics. 2002;161(4):1727-1750. doi:10.1093/genetics/161.4.1727 apa: Kirkpatrick, M., Johnson, T., & Barton, N. H. (2002). General models of multilocus evolution. Genetics. Genetics Society of America. https://doi.org/10.1093/genetics/161.4.1727 chicago: Kirkpatrick, Mark, Toby Johnson, and Nicholas H Barton. “General Models of Multilocus Evolution.” Genetics. Genetics Society of America, 2002. https://doi.org/10.1093/genetics/161.4.1727. ieee: M. Kirkpatrick, T. Johnson, and N. H. Barton, “General models of multilocus evolution,” Genetics, vol. 161, no. 4. Genetics Society of America, pp. 1727–1750, 2002. ista: Kirkpatrick M, Johnson T, Barton NH. 2002. General models of multilocus evolution. Genetics. 161(4), 1727–1750. mla: Kirkpatrick, Mark, et al. “General Models of Multilocus Evolution.” Genetics, vol. 161, no. 4, Genetics Society of America, 2002, pp. 1727–50, doi:10.1093/genetics/161.4.1727. short: M. Kirkpatrick, T. Johnson, N.H. Barton, Genetics 161 (2002) 1727–1750. date_created: 2018-12-11T12:04:17Z date_published: 2002-08-01T00:00:00Z date_updated: 2023-07-11T13:20:26Z day: '01' doi: 10.1093/genetics/161.4.1727 extern: '1' external_id: pmid: - '12196414' intvolume: ' 161' issue: '4' language: - iso: eng main_file_link: - open_access: '1' url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462196/ month: '08' oa: 1 oa_version: Published Version page: 1727 - 1750 pmid: 1 publication: Genetics publication_identifier: issn: - 0016-6731 publication_status: published publisher: Genetics Society of America publist_id: '2762' quality_controlled: '1' scopus_import: '1' status: public title: General models of multilocus evolution type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 161 year: '2002' ... --- _id: '3757' abstract: - lang: eng text: A central problem in biology is determining how genes interact as parts of functional networks. Creation and analysis of synthetic networks, composed of well-characterized genetic elements, provide a framework for theoretical modeling. Here, with the use of a combinatorial method, a library of networks with varying connectivity was generated in Escherichia coli. These networks were composed of genes encoding the transcriptional regulators Lacl, TetR, and lambda Cl, as well as the corresponding promoters. They displayed phenotypic behaviors resembling binary logical circuits, with two chemical “inputs” and a fluorescent protein “output.” Within this simple system, diverse computational functions arose through changes in network connectivity. Combinatorial synthesis provides an alternative approach for studying biological networks, as well as an efficient method for producing diverse phenotypes in vivo. article_processing_charge: No article_type: original author: - first_name: Calin C full_name: Guet, Calin C id: 47F8433E-F248-11E8-B48F-1D18A9856A87 last_name: Guet orcid: 0000-0001-6220-2052 - first_name: Michael full_name: Elowitz, Michael last_name: Elowitz - first_name: Weihong full_name: Hsing, Weihong last_name: Hsing - first_name: Stanislas full_name: Leibler, Stanislas last_name: Leibler citation: ama: Guet CC, Elowitz M, Hsing W, Leibler S. Combinatorial synthesis of genetic networks. Science. 2002;296(5572):1466-1470. doi:10.1126/science.1067407 apa: Guet, C. C., Elowitz, M., Hsing, W., & Leibler, S. (2002). Combinatorial synthesis of genetic networks. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1067407 chicago: Guet, Calin C, Michael Elowitz, Weihong Hsing, and Stanislas Leibler. “Combinatorial Synthesis of Genetic Networks.” Science. American Association for the Advancement of Science, 2002. https://doi.org/10.1126/science.1067407. ieee: C. C. Guet, M. Elowitz, W. Hsing, and S. Leibler, “Combinatorial synthesis of genetic networks,” Science, vol. 296, no. 5572. American Association for the Advancement of Science, pp. 1466–1470, 2002. ista: Guet CC, Elowitz M, Hsing W, Leibler S. 2002. Combinatorial synthesis of genetic networks. Science. 296(5572), 1466–1470. mla: Guet, Calin C., et al. “Combinatorial Synthesis of Genetic Networks.” Science, vol. 296, no. 5572, American Association for the Advancement of Science, 2002, pp. 1466–70, doi:10.1126/science.1067407. short: C.C. Guet, M. Elowitz, W. Hsing, S. Leibler, Science 296 (2002) 1466–1470. date_created: 2018-12-11T12:05:00Z date_published: 2002-05-24T00:00:00Z date_updated: 2023-07-11T12:48:53Z day: '24' doi: 10.1126/science.1067407 extern: '1' external_id: pmid: - '12029133' intvolume: ' 296' issue: '5572' language: - iso: eng month: '05' oa_version: None page: 1466 - 1470 pmid: 1 publication: Science publication_identifier: issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science publist_id: '2471' quality_controlled: '1' scopus_import: '1' status: public title: Combinatorial synthesis of genetic networks type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 296 year: '2002' ... --- _id: '3497' abstract: - lang: eng text: The use of advanced patch-clamp recording techniques in brain slices, such as simultaneous recording from multiple neurons and recording from dendrites or presynaptic terminals, demands slices of the highest quality. In this context the mechanics of the tissue slicer are an important factor. Ideally, a tissue slicer should generate large-amplitude and high-frequency movements of the cutting blade in a horizontal axis, with minimal vibrations in the vertical axis. We developed a vibroslicer that fulfils these in part conflicting requirements. The oscillator is a permanent-magnet-coil-leaf-spring system. Using an auto-resonant mechano-electrical feedback circuit, large horizontal oscillations (up to 3 mm peak-to-peak) with high frequency (,90 Hz) are generated. To minimize vertical vibrations, an adjustment mechanism was employed that allowed alignment of the cutting edge of the blade with the major axis of the oscillation. A vibroprobe device was used to monitor vertical vibrations during adjustment. The system is based on the shading of the light path between a light-emitting diode (LED) and a photodiode. Vibroprobe monitoring revealed that the vibroslicer, after appropriate adjustment, generated vertical vibrations of <1 µm, significantly less than many commercial tissue slicers. Light- and electron-microscopic analysis of surface layers of slices cut with the vibroslicer showed that cellular elements, dendritic processes and presynaptic terminals are well preserved under these conditions, as required for patch-clamp recording from these structures. acknowledgement: "We thank Dr. M. Frotscher for reading the manuscript, and H. Kressner, R. Laufersweiler, and A. Bühler for help with the construction of several prototypes of vibroslicer and vibroprobe. We also thank A. Blomenkamp, K. Winterhalter, B. Joch, and A. Schneider for technical assistance. This work was supported by grants of the Deutsche Forschungsgemeinschaft\r\n(SFB 505/C5, C6) and the Human Frontiers Science Program Organization (RG0017/1998-B)." article_processing_charge: No article_type: original author: - first_name: Jörg full_name: Geiger, Jörg last_name: Geiger - first_name: Joseph full_name: Bischofberger, Joseph last_name: Bischofberger - first_name: Imre full_name: Vida, Imre last_name: Vida - first_name: Ulrich full_name: Fröbe, Ulrich last_name: Fröbe - first_name: S full_name: Pfitzinger, S last_name: Pfitzinger - first_name: H. full_name: Weber, H. last_name: Weber - first_name: Klaus full_name: Haverkampf, Klaus last_name: Haverkampf - first_name: Peter M full_name: Jonas, Peter M id: 353C1B58-F248-11E8-B48F-1D18A9856A87 last_name: Jonas orcid: 0000-0001-5001-4804 citation: ama: 'Geiger J, Bischofberger J, Vida I, et al. Patch-clamp recording in brain slices with improved slicer technology. Pflugers Archiv : European Journal of Physiology. 2002;443(3):491-501. doi:10.1007/s00424-001-0735-3' apa: 'Geiger, J., Bischofberger, J., Vida, I., Fröbe, U., Pfitzinger, S., Weber, H., … Jonas, P. M. (2002). Patch-clamp recording in brain slices with improved slicer technology. Pflugers Archiv : European Journal of Physiology. Springer. https://doi.org/10.1007/s00424-001-0735-3' chicago: 'Geiger, Jörg, Joseph Bischofberger, Imre Vida, Ulrich Fröbe, S Pfitzinger, H. Weber, Klaus Haverkampf, and Peter M Jonas. “Patch-Clamp Recording in Brain Slices with Improved Slicer Technology.” Pflugers Archiv : European Journal of Physiology. Springer, 2002. https://doi.org/10.1007/s00424-001-0735-3.' ieee: 'J. Geiger et al., “Patch-clamp recording in brain slices with improved slicer technology,” Pflugers Archiv : European Journal of Physiology, vol. 443, no. 3. Springer, pp. 491–501, 2002.' ista: 'Geiger J, Bischofberger J, Vida I, Fröbe U, Pfitzinger S, Weber H, Haverkampf K, Jonas PM. 2002. Patch-clamp recording in brain slices with improved slicer technology. Pflugers Archiv : European Journal of Physiology. 443(3), 491–501.' mla: 'Geiger, Jörg, et al. “Patch-Clamp Recording in Brain Slices with Improved Slicer Technology.” Pflugers Archiv : European Journal of Physiology, vol. 443, no. 3, Springer, 2002, pp. 491–501, doi:10.1007/s00424-001-0735-3.' short: 'J. Geiger, J. Bischofberger, I. Vida, U. Fröbe, S. Pfitzinger, H. Weber, K. Haverkampf, P.M. Jonas, Pflugers Archiv : European Journal of Physiology 443 (2002) 491–501.' date_created: 2018-12-11T12:03:38Z date_published: 2002-01-01T00:00:00Z date_updated: 2023-07-17T07:36:37Z day: '01' doi: 10.1007/s00424-001-0735-3 extern: '1' external_id: pmid: - '11810221' intvolume: ' 443' issue: '3' language: - iso: eng month: '01' oa_version: None page: 491 - 501 pmid: 1 publication: 'Pflugers Archiv : European Journal of Physiology' publication_identifier: issn: - 0031-6768 publication_status: published publisher: Springer publist_id: '2890' quality_controlled: '1' scopus_import: '1' status: public title: Patch-clamp recording in brain slices with improved slicer technology type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 443 year: '2002' ... --- _id: '3533' abstract: - lang: eng text: 'Information in neuronal networks is thought to be represented by the rate of discharge and the temporal relationship between the discharging neurons. The discharge frequency of neurons is affected by their afferents and intrinsic properties, and shows great individual variability. The temporal coordination of neurons is greatly facilitated by network oscillations. In the hippocampus, population synchrony fluctuates during theta and gamma oscillations (10-100 ms scale) and can increase almost 10-fold during sharp wave bursts. Despite these large changes in excitability in the sub-second scale, longer-term (minute-scale) firing rates of individual neurons are relatively constant in an unchanging environment. As a result, mean hippocampal output remains stable over time. To understand the mechanisms responsible for this homeostasis, we address the following issues: (i) Can firing rates of single cells be modified? (ii) Once modified, what mechanism(s) can maintain the changes? We show that firing rates of hippocampal pyramidal cells can be altered in a novel environment and by Hebbian pairing of physiological input patterns with postsynaptic burst discharge. We also illustrate a competition between single spikes and the occurrence of spike bursts. Since spike-inducing (suprathreshold) inputs decrease the ability of strong (''teaching'') inputs to induce a burst discharge, we propose that the single spike versus burst competition presents a homeostatic regulatory mechanism to maintain synaptic strength and, consequently, firing rate in pyramidal cells.' article_processing_charge: No article_type: original author: - first_name: György full_name: Buzsáki, György last_name: Buzsáki - first_name: Jozsef L full_name: Csicsvari, Jozsef L id: 3FA14672-F248-11E8-B48F-1D18A9856A87 last_name: Csicsvari orcid: 0000-0002-5193-4036 - first_name: George full_name: Dragoi, George last_name: Dragoi - first_name: Kenneth full_name: Harris, Kenneth last_name: Harris - first_name: D. full_name: Henze, D. last_name: Henze - first_name: Hajima full_name: Hirase, Hajima last_name: Hirase citation: ama: Buzsáki G, Csicsvari JL, Dragoi G, Harris K, Henze D, Hirase H. Homeostatic maintenance of neuronal excitability by burst discharges in vivo. Cerebral Cortex. 2002;12(9):893-899. doi:10.1093/cercor/12.9.893 apa: Buzsáki, G., Csicsvari, J. L., Dragoi, G., Harris, K., Henze, D., & Hirase, H. (2002). Homeostatic maintenance of neuronal excitability by burst discharges in vivo. Cerebral Cortex. Oxford University Press. https://doi.org/10.1093/cercor/12.9.893 chicago: Buzsáki, György, Jozsef L Csicsvari, George Dragoi, Kenneth Harris, D. Henze, and Hajima Hirase. “Homeostatic Maintenance of Neuronal Excitability by Burst Discharges in Vivo.” Cerebral Cortex. Oxford University Press, 2002. https://doi.org/10.1093/cercor/12.9.893. ieee: G. Buzsáki, J. L. Csicsvari, G. Dragoi, K. Harris, D. Henze, and H. Hirase, “Homeostatic maintenance of neuronal excitability by burst discharges in vivo,” Cerebral Cortex, vol. 12, no. 9. Oxford University Press, pp. 893–899, 2002. ista: Buzsáki G, Csicsvari JL, Dragoi G, Harris K, Henze D, Hirase H. 2002. Homeostatic maintenance of neuronal excitability by burst discharges in vivo. Cerebral Cortex. 12(9), 893–899. mla: Buzsáki, György, et al. “Homeostatic Maintenance of Neuronal Excitability by Burst Discharges in Vivo.” Cerebral Cortex, vol. 12, no. 9, Oxford University Press, 2002, pp. 893–99, doi:10.1093/cercor/12.9.893. short: G. Buzsáki, J.L. Csicsvari, G. Dragoi, K. Harris, D. Henze, H. Hirase, Cerebral Cortex 12 (2002) 893–899. date_created: 2018-12-11T12:03:50Z date_published: 2002-09-01T00:00:00Z date_updated: 2023-07-17T07:27:12Z day: '01' doi: 10.1093/cercor/12.9.893 extern: '1' external_id: pmid: - '12183388' intvolume: ' 12' issue: '9' language: - iso: eng month: '09' oa_version: None page: 893 - 899 pmid: 1 publication: Cerebral Cortex publication_identifier: issn: - 1047-3211 publication_status: published publisher: Oxford University Press publist_id: '2851' quality_controlled: '1' scopus_import: '1' status: public title: Homeostatic maintenance of neuronal excitability by burst discharges in vivo type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 12 year: '2002' ... --- _id: '3424' abstract: - lang: eng text: "We give a brief overview of the current understanding of the explosion mechanism of core collapse supernovae. Our main focus is the impact of rotation on the explosion. Recent observations of the polarization of the light emitted by supernova explosions indicate that there are large deviations from spherical symmetry in the very heart of the explosion the origin of which is unknown. We use the new approach of a three dimensional test particle based simulation to simulate the infall phase of a supernova event. The underlying microphysics is simplified to make this computationally possible. A systematic study of the influence of rotation mainly during the infall phase of the collapse of a typical iron core is performed. Indications for significant deviations from spherical symmetry are found in our very rapidly rotating models. © 2002 American Institute of Physics\r\n" alternative_title: - Exotic Clustering, American Institute of Physics Conference Proceedings article_processing_charge: No author: - first_name: Mark Tobias full_name: Bollenbach, Mark Tobias id: 3E6DB97A-F248-11E8-B48F-1D18A9856A87 last_name: Bollenbach orcid: 0000-0003-4398-476X - first_name: Wolfgang full_name: Bauer, Wolfgang last_name: Bauer citation: ama: 'Bollenbach MT, Bauer W. 3d supernovae collapse calculations. In: Vol 644. American Institute of Physics; 2002:219-232. doi:10.1063/1.1523196 ' apa: 'Bollenbach, M. T., & Bauer, W. (2002). 3d supernovae collapse calculations (Vol. 644, pp. 219–232). Presented at the CRIS: Catania Relativistic Ion Studies , Catania, Italy: American Institute of Physics. https://doi.org/10.1063/1.1523196 ' chicago: Bollenbach, Mark Tobias, and Wolfgang Bauer. “3d Supernovae Collapse Calculations,” 644:219–32. American Institute of Physics, 2002. https://doi.org/10.1063/1.1523196 . ieee: 'M. T. Bollenbach and W. Bauer, “3d supernovae collapse calculations,” presented at the CRIS: Catania Relativistic Ion Studies , Catania, Italy, 2002, vol. 644, pp. 219–232.' ista: 'Bollenbach MT, Bauer W. 2002. 3d supernovae collapse calculations. CRIS: Catania Relativistic Ion Studies , Exotic Clustering, American Institute of Physics Conference Proceedings, vol. 644, 219–232.' mla: Bollenbach, Mark Tobias, and Wolfgang Bauer. 3d Supernovae Collapse Calculations. Vol. 644, American Institute of Physics, 2002, pp. 219–32, doi:10.1063/1.1523196 . short: M.T. Bollenbach, W. Bauer, in:, American Institute of Physics, 2002, pp. 219–232. conference: end_date: 2002-06-14 location: Catania, Italy name: 'CRIS: Catania Relativistic Ion Studies ' start_date: 2002-06-10 date_created: 2018-12-11T12:03:15Z date_published: 2002-11-26T00:00:00Z date_updated: 2023-07-17T11:05:27Z day: '26' doi: '10.1063/1.1523196 ' extern: '1' intvolume: ' 644' language: - iso: eng month: '11' oa_version: None page: 219 - 232 publication_identifier: isbn: - '9781510832008' publication_status: published publisher: American Institute of Physics publist_id: '2977' quality_controlled: '1' status: public title: 3d supernovae collapse calculations type: conference user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 644 year: '2002' ... --- _id: '2988' abstract: - lang: eng text: Coordination of cell and tissue polarity commonly involves directional signaling [1]. In the Arabidopsis root epidermis, cell polarity is revealed by basal, root tip-oriented, hair outgrowth from hair-forming cells (trichoblasts) [2]. The plant hormone auxin displays polar movements [1, 3] and accumulates at maximum concentration in the root tip [4, 5]. The application of polar auxin transport inhibitors [3] evokes changes in trichoblast polarity only at high concentrations and after long-term application [2, 4]. Thus, it remains open whether components of the auxin transport machinery mediate establishment of trichoblast polarity. Here we report that the presumptive auxin influx carrier AUX1 [6, 7] contributes to apical-basal hair cell polarity. AUX1 function is required for polarity changes induced by exogenous application of the auxin 2,4-D, a preferential influx carrier substrate. Similar to aux1 mutants, the vesicle trafficking inhibitor brefeldin A (BFA) interferes with polar hair initiation, and AUX1 function is required for BFA-mediated polarity changes. Consistently, BFA inhibits membrane trafficking of AUX1, trichoblast hyperpolarization induced by 2,4-D, and alters the distal auxin maximum. Our results identify AUX1 as one component of a novel BFA-sensitive auxin transport pathway polarizing cells toward a hormone maximum. article_processing_charge: No article_type: original author: - first_name: Markus full_name: Grebe, Markus last_name: Grebe - first_name: Jirí full_name: Friml, Jirí id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 - first_name: Ranjan full_name: Swarup, Ranjan last_name: Swarup - first_name: Karin full_name: Ljung, Karin last_name: Ljung - first_name: Göran full_name: Sandberg, Göran last_name: Sandberg - first_name: Maarten full_name: Terlou, Maarten last_name: Terlou - first_name: Klaus full_name: Palme, Klaus last_name: Palme - first_name: Malcolm full_name: Bennett, Malcolm last_name: Bennett - first_name: Ben full_name: Scheres, Ben last_name: Scheres citation: ama: Grebe M, Friml J, Swarup R, et al. Cell polarity signaling in Arabidopsis involves a BFA sensitive auxin influx pathway. Current Biology. 2002;12(4):329-334. doi:10.1016/S0960-9822(02)00654-1 apa: Grebe, M., Friml, J., Swarup, R., Ljung, K., Sandberg, G., Terlou, M., … Scheres, B. (2002). Cell polarity signaling in Arabidopsis involves a BFA sensitive auxin influx pathway. Current Biology. Cell Press. https://doi.org/10.1016/S0960-9822(02)00654-1 chicago: Grebe, Markus, Jiří Friml, Ranjan Swarup, Karin Ljung, Göran Sandberg, Maarten Terlou, Klaus Palme, Malcolm Bennett, and Ben Scheres. “Cell Polarity Signaling in Arabidopsis Involves a BFA Sensitive Auxin Influx Pathway.” Current Biology. Cell Press, 2002. https://doi.org/10.1016/S0960-9822(02)00654-1. ieee: M. Grebe et al., “Cell polarity signaling in Arabidopsis involves a BFA sensitive auxin influx pathway,” Current Biology, vol. 12, no. 4. Cell Press, pp. 329–334, 2002. ista: Grebe M, Friml J, Swarup R, Ljung K, Sandberg G, Terlou M, Palme K, Bennett M, Scheres B. 2002. Cell polarity signaling in Arabidopsis involves a BFA sensitive auxin influx pathway. Current Biology. 12(4), 329–334. mla: Grebe, Markus, et al. “Cell Polarity Signaling in Arabidopsis Involves a BFA Sensitive Auxin Influx Pathway.” Current Biology, vol. 12, no. 4, Cell Press, 2002, pp. 329–34, doi:10.1016/S0960-9822(02)00654-1. short: M. Grebe, J. Friml, R. Swarup, K. Ljung, G. Sandberg, M. Terlou, K. Palme, M. Bennett, B. Scheres, Current Biology 12 (2002) 329–334. date_created: 2018-12-11T12:00:43Z date_published: 2002-02-19T00:00:00Z date_updated: 2023-07-17T12:15:28Z day: '19' doi: 10.1016/S0960-9822(02)00654-1 extern: '1' external_id: pmid: - '11864575' intvolume: ' 12' issue: '4' language: - iso: eng month: '02' oa_version: None page: 329 - 334 pmid: 1 publication: Current Biology publication_identifier: issn: - 0960-9822 publication_status: published publisher: Cell Press publist_id: '3714' quality_controlled: '1' scopus_import: '1' status: public title: Cell polarity signaling in Arabidopsis involves a BFA sensitive auxin influx pathway type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 12 year: '2002' ... --- _id: '3421' abstract: - lang: eng text: Single molecule experiments provide insight into the individuality of biological macromolecules, their unique function, reaction pathways, trajectories and molecular interactions. The exceptional signal-to-noise ratio of the atomic force microscope allows individual proteins to be imaged under physiologically relevant conditions at a lateral resolution of 0.5–1 nm and a vertical resolution of 0.1–0.2 nm. Recently, it has become possible to observe single molecule events using this technique. This capability is reviewed on various water-soluble and membrane proteins. Examples of the observation of function, variability, and assembly of single proteins are discussed. Statistical analysis is important to extend conclusions derived from single molecule experiments to protein species. Such approaches allow the classification of protein conformations and movements. Recent developments of probe microscopy techniques allow simultaneous measurement of multiple signals on individual macromolecules, and greatly extend the range of experiments possible for probing biological systems at the molecular level. Biologists exploring molecular mechanisms will benefit from a burgeoning of scanning probe microscopes and of their future combination with molecular biological experiments. article_processing_charge: No article_type: review author: - first_name: Daniel full_name: Mueller, Daniel last_name: Mueller - first_name: Harald L full_name: Janovjak, Harald L id: 33BA6C30-F248-11E8-B48F-1D18A9856A87 last_name: Janovjak orcid: 0000-0002-8023-9315 - first_name: Tiina full_name: Lehto, Tiina last_name: Lehto - first_name: Lars full_name: Kuerschner, Lars last_name: Kuerschner - first_name: Kurt full_name: Anderson, Kurt last_name: Anderson citation: ama: Mueller D, Janovjak HL, Lehto T, Kuerschner L, Anderson K. Observing structure, function and assembly of single proteins by AFM. Progress in Biophysics and Molecular Biology. 2002;79(1-3):1-43. doi:10.1016/S0079-6107(02)00009-3 apa: Mueller, D., Janovjak, H. L., Lehto, T., Kuerschner, L., & Anderson, K. (2002). Observing structure, function and assembly of single proteins by AFM. Progress in Biophysics and Molecular Biology. Elsevier. https://doi.org/10.1016/S0079-6107(02)00009-3 chicago: Mueller, Daniel, Harald L Janovjak, Tiina Lehto, Lars Kuerschner, and Kurt Anderson. “Observing Structure, Function and Assembly of Single Proteins by AFM.” Progress in Biophysics and Molecular Biology. Elsevier, 2002. https://doi.org/10.1016/S0079-6107(02)00009-3. ieee: D. Mueller, H. L. Janovjak, T. Lehto, L. Kuerschner, and K. Anderson, “Observing structure, function and assembly of single proteins by AFM,” Progress in Biophysics and Molecular Biology, vol. 79, no. 1–3. Elsevier, pp. 1–43, 2002. ista: Mueller D, Janovjak HL, Lehto T, Kuerschner L, Anderson K. 2002. Observing structure, function and assembly of single proteins by AFM. Progress in Biophysics and Molecular Biology. 79(1–3), 1–43. mla: Mueller, Daniel, et al. “Observing Structure, Function and Assembly of Single Proteins by AFM.” Progress in Biophysics and Molecular Biology, vol. 79, no. 1–3, Elsevier, 2002, pp. 1–43, doi:10.1016/S0079-6107(02)00009-3. short: D. Mueller, H.L. Janovjak, T. Lehto, L. Kuerschner, K. Anderson, Progress in Biophysics and Molecular Biology 79 (2002) 1–43. date_created: 2018-12-11T12:03:14Z date_published: 2002-05-01T00:00:00Z date_updated: 2023-07-17T11:36:32Z day: '01' doi: 10.1016/S0079-6107(02)00009-3 extern: '1' external_id: pmid: - '12225775' intvolume: ' 79' issue: 1-3 language: - iso: eng month: '05' oa_version: None page: 1 - 43 pmid: 1 publication: Progress in Biophysics and Molecular Biology publication_identifier: issn: - 0079-6107 publication_status: published publisher: Elsevier publist_id: '2980' quality_controlled: '1' scopus_import: '1' status: public title: Observing structure, function and assembly of single proteins by AFM type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 79 year: '2002' ... --- _id: '2989' abstract: - lang: eng text: In contrast to animals, little is known about pattern formation in plants. Physiological and genetic data suggest the involvement of the phytohormone auxin in this process. Here, we characterize a novel member of the PIN family of putative auxin efflux carriers, Arabidopsis PIN4, that is localized in developing and mature root meristems. Atpin4 mutants are defective in establishment and maintenance of endogenous auxin gradients, fail to canalize externally applied auxin, and display various patterning defects in both embryonic and seedling roots. We propose a role for AtPIN4 in generating a sink for auxin below the quiescent center of the root meristem that is essential for auxin distribution and patterning. acknowledgement: We thank Petra Tänzler, Michaela Lehnen, and Thomas Steinmann for technical help. We acknowledge the Arabidopsis Biological Resource Center (Columbus, OH) and Thomas Altman for providing material. We also gratefully acknowledge the ADIS service group for DNA sequencing and ZIGIA (Center for Functional Genomics in Arabidopsis) for the En lines. We are grateful to our colleagues, particularly Leo Gälweiler, Niko Geldner, Matthias Godde, and Kathrin Schrick for critical reading of the manuscript. This work was supported by a fellowship of the Deutscher Akademischer Austauschdienset (J.F.), the Deutsche Forschungsgemeinschaft (Schwerpunktprogramm Phytohormone), the European Communities Biotechnology Programs, the Fonds der Chemischen Industrie, and the INCO-Copernicus Program. article_processing_charge: No article_type: original author: - first_name: Jirí full_name: Friml, Jirí id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 - first_name: Eva full_name: Benková, Eva id: 38F4F166-F248-11E8-B48F-1D18A9856A87 last_name: Benková orcid: 0000-0002-8510-9739 - first_name: Ikram full_name: Blilou, Ikram last_name: Blilou - first_name: Justyna full_name: Wiśniewska, Justyna last_name: Wiśniewska - first_name: Thorsten full_name: Hamann, Thorsten last_name: Hamann - first_name: Karin full_name: Ljung, Karin last_name: Ljung - first_name: Scott full_name: Woody, Scott last_name: Woody - first_name: Göran full_name: Sandberg, Göran last_name: Sandberg - first_name: Ben full_name: Scheres, Ben last_name: Scheres - first_name: Gerd full_name: Jürgens, Gerd last_name: Jürgens - first_name: Klaus full_name: Palme, Klaus last_name: Palme citation: ama: Friml J, Benková E, Blilou I, et al. AtPIN4 mediates sink-driven auxin gradients and root patterning in Arabidopsis. Cell. 2002;108(5):661-673. doi:10.1016/S0092-8674(02)00656-6 apa: Friml, J., Benková, E., Blilou, I., Wiśniewska, J., Hamann, T., Ljung, K., … Palme, K. (2002). AtPIN4 mediates sink-driven auxin gradients and root patterning in Arabidopsis. Cell. Cell Press. https://doi.org/10.1016/S0092-8674(02)00656-6 chicago: Friml, Jiří, Eva Benková, Ikram Blilou, Justyna Wiśniewska, Thorsten Hamann, Karin Ljung, Scott Woody, et al. “AtPIN4 Mediates Sink-Driven Auxin Gradients and Root Patterning in Arabidopsis.” Cell. Cell Press, 2002. https://doi.org/10.1016/S0092-8674(02)00656-6. ieee: J. Friml et al., “AtPIN4 mediates sink-driven auxin gradients and root patterning in Arabidopsis,” Cell, vol. 108, no. 5. Cell Press, pp. 661–673, 2002. ista: Friml J, Benková E, Blilou I, Wiśniewska J, Hamann T, Ljung K, Woody S, Sandberg G, Scheres B, Jürgens G, Palme K. 2002. AtPIN4 mediates sink-driven auxin gradients and root patterning in Arabidopsis. Cell. 108(5), 661–673. mla: Friml, Jiří, et al. “AtPIN4 Mediates Sink-Driven Auxin Gradients and Root Patterning in Arabidopsis.” Cell, vol. 108, no. 5, Cell Press, 2002, pp. 661–73, doi:10.1016/S0092-8674(02)00656-6. short: J. Friml, E. Benková, I. Blilou, J. Wiśniewska, T. Hamann, K. Ljung, S. Woody, G. Sandberg, B. Scheres, G. Jürgens, K. Palme, Cell 108 (2002) 661–673. date_created: 2018-12-11T12:00:43Z date_published: 2002-03-08T00:00:00Z date_updated: 2023-07-17T11:57:40Z day: '08' doi: 10.1016/S0092-8674(02)00656-6 extern: '1' external_id: pmid: - '11893337' intvolume: ' 108' issue: '5' language: - iso: eng month: '03' oa_version: None page: 661 - 673 pmid: 1 publication: Cell publication_identifier: issn: - 0092-8674 publication_status: published publisher: Cell Press publist_id: '3713' quality_controlled: '1' scopus_import: '1' status: public title: AtPIN4 mediates sink-driven auxin gradients and root patterning in Arabidopsis type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 108 year: '2002' ... --- _id: '3422' abstract: - lang: eng text: Quantitative real-time PCR represents a highly sensitive and powerful technique for the quantitation of nucleic acids. It has a tremendous potential for the high-throughput analysis of gene expression in research and routine diagnostics. However, the major hurdle is not the practical performance of the experiments themselves but rather the efficient evaluation and the mathematical and statistical analysis of the enormous amount of data gained by this technology, as these functions are not included in the software provided by the manufacturers of the detection systems. In this work, we focus on the mathematical evaluation and analysis of the data generated by quantitative real-time PCR, the calculation of the final results, the propagation of experimental variation of the measured values to the final results, and the statistical analysis. We developed a Microsoft Excel-based software application coded in Visual Basic for Applications, called Q-Gene, which addresses these points. Q-Gene manages and expedites the planning, performance, and evaluation of quantitative real-time PCR experiments, as well as the mathematical and statistical analysis, storage, and graphical presentation of the data. The Q-Gene software application is a tool to cope with complex quantitative real-time PCR experiments at a high-throughput scale and considerably expedites and rationalizes the experimental setup, data analysis, and data management while ensuring highest reproducibility. article_processing_charge: No article_type: original author: - first_name: Patrick full_name: Müller, Patrick last_name: Müller - first_name: Harald L full_name: Janovjak, Harald L id: 33BA6C30-F248-11E8-B48F-1D18A9856A87 last_name: Janovjak orcid: 0000-0002-8023-9315 - first_name: Andre full_name: Miserez, Andre last_name: Miserez - first_name: Zuzana full_name: Dobbie, Zuzana last_name: Dobbie citation: ama: Müller P, Janovjak HL, Miserez A, Dobbie Z. Processing of gene expression data generated by quantitative real-time RT-PCR. Biotechniques. 2002;32(6):1372-1379. apa: Müller, P., Janovjak, H. L., Miserez, A., & Dobbie, Z. (2002). Processing of gene expression data generated by quantitative real-time RT-PCR. Biotechniques. Informa Healthcare. chicago: Müller, Patrick, Harald L Janovjak, Andre Miserez, and Zuzana Dobbie. “Processing of Gene Expression Data Generated by Quantitative Real-Time RT-PCR.” Biotechniques. Informa Healthcare, 2002. ieee: P. Müller, H. L. Janovjak, A. Miserez, and Z. Dobbie, “Processing of gene expression data generated by quantitative real-time RT-PCR,” Biotechniques, vol. 32, no. 6. Informa Healthcare, pp. 1372–1379, 2002. ista: Müller P, Janovjak HL, Miserez A, Dobbie Z. 2002. Processing of gene expression data generated by quantitative real-time RT-PCR. Biotechniques. 32(6), 1372–1379. mla: Müller, Patrick, et al. “Processing of Gene Expression Data Generated by Quantitative Real-Time RT-PCR.” Biotechniques, vol. 32, no. 6, Informa Healthcare, 2002, pp. 1372–79. short: P. Müller, H.L. Janovjak, A. Miserez, Z. Dobbie, Biotechniques 32 (2002) 1372–1379. date_created: 2018-12-11T12:03:15Z date_published: 2002-06-01T00:00:00Z date_updated: 2023-07-17T11:29:06Z day: '01' extern: '1' external_id: pmid: - '12074169' intvolume: ' 32' issue: '6' language: - iso: eng month: '06' oa_version: None page: 1372 - 1379 pmid: 1 publication: Biotechniques publication_identifier: issn: - 0736-6205 publication_status: published publisher: Informa Healthcare publist_id: '2979' quality_controlled: '1' scopus_import: '1' status: public title: Processing of gene expression data generated by quantitative real-time RT-PCR type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 32 year: '2002' ... --- _id: '3140' abstract: - lang: eng text: The maturation of synaptic structures depends on inductive interactions between axons and their prospective targets. One example of such an interaction is the influence of proprioceptive sensory axons on the differentiation of muscle spindles. We have monitored the expression of three transcription factors, Egr3, Pea3, and Erm, that delineate early muscle spindle development in an assay of muscle spindle-inducing signals. We provide genetic evidence that Neuregulin1 (Nrg1) is required for proprioceptive afferent-evoked induction of muscle spindle differentiation in the mouse. Ig-Nrg1 isoforms are preferentially expressed by proprioceptive sensory neurons and are sufficient to induce muscle spindle differentiation in vivo, whereas CRD-Nrg1 isoforms are broadly expressed in sensory and motor neurons but are not required for muscle spindle induction. acknowledgement: We thank L. Role for generously providing the CRD-Nrg1 mutant allele for these studies, L. Parada and D. Anderson for sharing the TrkC and Ngn1 mouse strains, W. Tourtellotte for providing Egr3 mutant mice, E. Avetisova for expert technical assistance, X. Yang for experimental help in the initial phase of these studies, A. Garratt for advice with ErbB antibodies, and L. Role and G. Fischbach for helpful discussions. The CRD-Nrg1 mutant allele was generated in the lab of Dr. Lorna Role, with the support of NIH grant NS29071. S.A. and S.H. were supported by a grant from the Swiss National Science Foundation and the Kanton of Basel-Stadt. S.J.B. was supported by grants from the NINDS. N.A.S. was supported by a Howard Hughes Medical Institute Postdoctoral Fellowship for Physicians and a Career Development Award from the NINDS. T.M.J. was supported by grants from NINDS and is an Investigator of the Howard Hughes Medical Institute. article_processing_charge: No article_type: original author: - first_name: Simon full_name: Hippenmeyer, Simon id: 37B36620-F248-11E8-B48F-1D18A9856A87 last_name: Hippenmeyer orcid: 0000-0003-2279-1061 - first_name: Neil full_name: Shneider, Neil last_name: Shneider - first_name: Carmen full_name: Birchmeier, Carmen last_name: Birchmeier - first_name: Steven full_name: Burden, Steven last_name: Burden - first_name: Thomas full_name: Jessell, Thomas last_name: Jessell - first_name: Silvia full_name: Arber, Silvia last_name: Arber citation: ama: Hippenmeyer S, Shneider N, Birchmeier C, Burden S, Jessell T, Arber S. A role for Neuregulin1 signaling in muscle spindle differentiation. Neuron. 2002;36(6):1035-1049. doi:10.1016/S0896-6273(02)01101-7 apa: Hippenmeyer, S., Shneider, N., Birchmeier, C., Burden, S., Jessell, T., & Arber, S. (2002). A role for Neuregulin1 signaling in muscle spindle differentiation. Neuron. Elsevier. https://doi.org/10.1016/S0896-6273(02)01101-7 chicago: Hippenmeyer, Simon, Neil Shneider, Carmen Birchmeier, Steven Burden, Thomas Jessell, and Silvia Arber. “A Role for Neuregulin1 Signaling in Muscle Spindle Differentiation.” Neuron. Elsevier, 2002. https://doi.org/10.1016/S0896-6273(02)01101-7. ieee: S. Hippenmeyer, N. Shneider, C. Birchmeier, S. Burden, T. Jessell, and S. Arber, “A role for Neuregulin1 signaling in muscle spindle differentiation,” Neuron, vol. 36, no. 6. Elsevier, pp. 1035–1049, 2002. ista: Hippenmeyer S, Shneider N, Birchmeier C, Burden S, Jessell T, Arber S. 2002. A role for Neuregulin1 signaling in muscle spindle differentiation. Neuron. 36(6), 1035–1049. mla: Hippenmeyer, Simon, et al. “A Role for Neuregulin1 Signaling in Muscle Spindle Differentiation.” Neuron, vol. 36, no. 6, Elsevier, 2002, pp. 1035–49, doi:10.1016/S0896-6273(02)01101-7. short: S. Hippenmeyer, N. Shneider, C. Birchmeier, S. Burden, T. Jessell, S. Arber, Neuron 36 (2002) 1035–1049. date_created: 2018-12-11T12:01:37Z date_published: 2002-12-19T00:00:00Z date_updated: 2023-07-17T11:46:43Z day: '19' doi: 10.1016/S0896-6273(02)01101-7 extern: '1' external_id: pmid: - '12495620' intvolume: ' 36' issue: '6' language: - iso: eng month: '12' oa_version: None page: 1035 - 1049 pmid: 1 publication: Neuron publication_identifier: issn: - 0896-6273 publication_status: published publisher: Elsevier publist_id: '3558' quality_controlled: '1' scopus_import: '1' status: public title: A role for Neuregulin1 signaling in muscle spindle differentiation type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 36 year: '2002' ... --- _id: '3423' article_processing_charge: No author: - first_name: Wolfgang full_name: Bauer, Wolfgang last_name: Bauer - first_name: Mark Tobias full_name: Bollenbach, Mark Tobias id: 3E6DB97A-F248-11E8-B48F-1D18A9856A87 last_name: Bollenbach orcid: 0000-0003-4398-476X - first_name: Marko full_name: Kleine Berkenbusch, Marko last_name: Kleine Berkenbusch - first_name: Holger full_name: Harreis, Holger last_name: Harreis citation: ama: 'Bauer W, Bollenbach MT, Kleine Berkenbusch M, Harreis H. The percolation interpretation of the nuclear fragmentation phase transition. In: Proceedings of the 18th Winter Workshop on Nuclear Dynamics. EP Systema; 2002:111-118.' apa: 'Bauer, W., Bollenbach, M. T., Kleine Berkenbusch, M., & Harreis, H. (2002). The percolation interpretation of the nuclear fragmentation phase transition. In Proceedings of the 18th Winter Workshop on Nuclear Dynamics (pp. 111–118). Nassau, Bahamas: EP Systema.' chicago: Bauer, Wolfgang, Mark Tobias Bollenbach, Marko Kleine Berkenbusch, and Holger Harreis. “The Percolation Interpretation of the Nuclear Fragmentation Phase Transition.” In Proceedings of the 18th Winter Workshop on Nuclear Dynamics, 111–18. EP Systema, 2002. ieee: W. Bauer, M. T. Bollenbach, M. Kleine Berkenbusch, and H. Harreis, “The percolation interpretation of the nuclear fragmentation phase transition,” in Proceedings of the 18th Winter Workshop on Nuclear Dynamics, Nassau, Bahamas, 2002, pp. 111–118. ista: Bauer W, Bollenbach MT, Kleine Berkenbusch M, Harreis H. 2002. The percolation interpretation of the nuclear fragmentation phase transition. Proceedings of the 18th Winter Workshop on Nuclear Dynamics. Winter Workshop on Nuclear Dynamics, 111–118. mla: Bauer, Wolfgang, et al. “The Percolation Interpretation of the Nuclear Fragmentation Phase Transition.” Proceedings of the 18th Winter Workshop on Nuclear Dynamics, EP Systema, 2002, pp. 111–18. short: W. Bauer, M.T. Bollenbach, M. Kleine Berkenbusch, H. Harreis, in:, Proceedings of the 18th Winter Workshop on Nuclear Dynamics, EP Systema, 2002, pp. 111–118. conference: end_date: 2002-01-22 location: Nassau, Bahamas name: Winter Workshop on Nuclear Dynamics start_date: 2002-01-20 date_created: 2018-12-11T12:03:15Z date_published: 2002-01-01T00:00:00Z date_updated: 2023-07-17T11:15:14Z day: '01' extern: '1' language: - iso: eng month: '01' oa_version: None page: 111 - 118 publication: Proceedings of the 18th Winter Workshop on Nuclear Dynamics publication_status: published publisher: EP Systema publist_id: '2978' status: public title: The percolation interpretation of the nuclear fragmentation phase transition type: conference user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 year: '2002' ... --- _id: '2986' abstract: - lang: eng text: Long-standing models propose that plant growth responses to light or gravity are mediated by asymmetric distribution of the phytohormone auxin. Physiological studies implicated a specific transport system that relocates auxin laterally, thereby effecting differential growth; however, neither the molecular components of this system nor the cellular mechanism of auxin redistribution on light or gravity perception have been identified. Here, we show that auxin accumulates asymmetrically during differential growth in an efflux-dependent manner. Mutations in the Arabidopsis gene PIN3, a regulator of auxin efflux, alter differential growth. PIN3 is expressed in gravity-sensing tissues, with PIN3 protein accumulating predominantly at the lateral cell surface. PIN3 localizes to the plasma membrane and to vesicles that cycle in an actin-dependent manner. In the root columella, PIN3 is positioned symmetrically at the plasma membrane but rapidly relocalizes laterally on gravity stimulation. Our data indicate that PIN3 is a component of the lateral auxin transport system regulating tropic growth. In addition, actin-dependent relocalization of PIN3 in response to gravity provides a mechanism for redirecting auxin flux to trigger asymmetric growth. acknowledgement: We thank G. Jürgens for enabling J.F. to accomplish part of this work in his laboratory; P. Tänzler and M. Sauer for technical assistance; H. Vahlenkamp for technical assistance in immunocytochemistry; M. Estelle for providing material and suggestions; T. Altman for BAC filter sets; the ADIS (Automated DNA Isolation and Sequencing) service group for DNA sequencing; ZIGIA (Center for Functional Genomics in Arabidopsis) for the En lines; and N. Geldner, T. Hamann, G. Jürgens, K. Schrick and C. Schwechheimer for comments and critical reading of the manuscript. This work was supported by a fellowship of the DAAD (J.F.), the DFG (Schwerpunktprogramm Phytohormone), the Fonds der chemischen Industrie, the European Communities Biotechnology Programs, the INCO-Copernicus Program and the European Space Agency MAP-Biotechnology Programme article_processing_charge: No article_type: original author: - first_name: Jirí full_name: Friml, Jirí id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 - first_name: Justyna full_name: Wiśniewska, Justyna last_name: Wiśniewska - first_name: Eva full_name: Benková, Eva id: 38F4F166-F248-11E8-B48F-1D18A9856A87 last_name: Benková orcid: 0000-0002-8510-9739 - first_name: Kurt full_name: Mendgen, Kurt last_name: Mendgen - first_name: Klaus full_name: Palme, Klaus last_name: Palme citation: ama: Friml J, Wiśniewska J, Benková E, Mendgen K, Palme K. Lateral relocation of auxin efflux regulator PIN3 mediates tropism in Arabidopsis. Nature. 2002;415(6873):806-809. doi:10.1038/415806a apa: Friml, J., Wiśniewska, J., Benková, E., Mendgen, K., & Palme, K. (2002). Lateral relocation of auxin efflux regulator PIN3 mediates tropism in Arabidopsis. Nature. Nature Publishing Group. https://doi.org/10.1038/415806a chicago: Friml, Jiří, Justyna Wiśniewska, Eva Benková, Kurt Mendgen, and Klaus Palme. “Lateral Relocation of Auxin Efflux Regulator PIN3 Mediates Tropism in Arabidopsis.” Nature. Nature Publishing Group, 2002. https://doi.org/10.1038/415806a. ieee: J. Friml, J. Wiśniewska, E. Benková, K. Mendgen, and K. Palme, “Lateral relocation of auxin efflux regulator PIN3 mediates tropism in Arabidopsis,” Nature, vol. 415, no. 6873. Nature Publishing Group, pp. 806–809, 2002. ista: Friml J, Wiśniewska J, Benková E, Mendgen K, Palme K. 2002. Lateral relocation of auxin efflux regulator PIN3 mediates tropism in Arabidopsis. Nature. 415(6873), 806–809. mla: Friml, Jiří, et al. “Lateral Relocation of Auxin Efflux Regulator PIN3 Mediates Tropism in Arabidopsis.” Nature, vol. 415, no. 6873, Nature Publishing Group, 2002, pp. 806–09, doi:10.1038/415806a. short: J. Friml, J. Wiśniewska, E. Benková, K. Mendgen, K. Palme, Nature 415 (2002) 806–809. date_created: 2018-12-11T12:00:42Z date_published: 2002-02-14T00:00:00Z date_updated: 2023-07-18T07:30:27Z day: '14' doi: 10.1038/415806a extern: '1' external_id: pmid: - '11845211 ' intvolume: ' 415' issue: '6873' language: - iso: eng month: '02' oa_version: None page: 806 - 809 pmid: 1 publication: Nature publication_identifier: issn: - 0028-0836 publication_status: published publisher: Nature Publishing Group publist_id: '3715' quality_controlled: '1' scopus_import: '1' status: public title: Lateral relocation of auxin efflux regulator PIN3 mediates tropism in Arabidopsis type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 415 year: '2002' ... --- _id: '2987' abstract: - lang: eng text: The hydra mutants of Arabidopsis are characterized by a pleiotropic phenotype that shows defective embryonic and seedling cell patterning, morphogenesis, and root growth. We demonstrate that the HYDRA1 gene encodes a Δ8-Δ7 sterol isomerase, whereas HYDRA2 encodes a sterol C14 reductase, previously identified as the FACKEL gene product. Seedlings mutant for each gene are similarly defective in the concentrations of the three major Arabidopsis sterols. Promoter::reporter gene analysis showed misexpression of the auxin-regulated DR5 and ACS1 promoters and of the epidermal cell file-specific GL2 promoter in the mutants. The mutants exhibit enhanced responses to auxin. The phenotypes can be rescued partially by inhibition of auxin and ethylene signaling but not by exogenous sterols or brassinosteroids. We propose a model in which correct sterol profiles are required for regulated auxin and ethylene signaling through effects on membrane function. acknowledgement: We thank Dr. Ken Feldmann for providing prospective hyd alleles, Dr. Jane Murfett for providing DR5::GUS seed, Dr. D. Van Der Straeten for providing ACS1::GUS seed, Dr. John Schiefelbein for providing GL2::GFP seed, and Dr. Ottoline Leyser for axr1-12 and axr3-1 seed. etr1 and fk seed was obtained from the Nottingham Arabidopsis Stock Centre. This work was supported by a Biotechnology and Biological Science Research Council research studentship to M.S., a Durham University studentship to M.P., and Biotechnology and Biological Science Research Council Grant 12/P02330 to J.T. article_processing_charge: No article_type: original author: - first_name: Martin full_name: Souter, Martin last_name: Souter - first_name: Jennifer full_name: Topping, Jennifer last_name: Topping - first_name: Margaret full_name: Pullen, Margaret last_name: Pullen - first_name: Jirí full_name: Friml, Jirí id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 - first_name: Klaus full_name: Palme, Klaus last_name: Palme - first_name: Rachel full_name: Hackett, Rachel last_name: Hackett - first_name: Don full_name: Grierson, Don last_name: Grierson - first_name: Keith full_name: Lindsey, Keith last_name: Lindsey citation: ama: Souter M, Topping J, Pullen M, et al. Hydra mutants of Arabidopsis are defective in sterol profiles and auxin and ethylene signaling. Plant Cell. 2002;14(5):1017-1031. doi:10.1105/tpc.001248 apa: Souter, M., Topping, J., Pullen, M., Friml, J., Palme, K., Hackett, R., … Lindsey, K. (2002). Hydra mutants of Arabidopsis are defective in sterol profiles and auxin and ethylene signaling. Plant Cell. American Society of Plant Biologists. https://doi.org/10.1105/tpc.001248 chicago: Souter, Martin, Jennifer Topping, Margaret Pullen, Jiří Friml, Klaus Palme, Rachel Hackett, Don Grierson, and Keith Lindsey. “Hydra Mutants of Arabidopsis Are Defective in Sterol Profiles and Auxin and Ethylene Signaling.” Plant Cell. American Society of Plant Biologists, 2002. https://doi.org/10.1105/tpc.001248. ieee: M. Souter et al., “Hydra mutants of Arabidopsis are defective in sterol profiles and auxin and ethylene signaling,” Plant Cell, vol. 14, no. 5. American Society of Plant Biologists, pp. 1017–1031, 2002. ista: Souter M, Topping J, Pullen M, Friml J, Palme K, Hackett R, Grierson D, Lindsey K. 2002. Hydra mutants of Arabidopsis are defective in sterol profiles and auxin and ethylene signaling. Plant Cell. 14(5), 1017–1031. mla: Souter, Martin, et al. “Hydra Mutants of Arabidopsis Are Defective in Sterol Profiles and Auxin and Ethylene Signaling.” Plant Cell, vol. 14, no. 5, American Society of Plant Biologists, 2002, pp. 1017–31, doi:10.1105/tpc.001248. short: M. Souter, J. Topping, M. Pullen, J. Friml, K. Palme, R. Hackett, D. Grierson, K. Lindsey, Plant Cell 14 (2002) 1017–1031. date_created: 2018-12-11T12:00:42Z date_published: 2002-05-01T00:00:00Z date_updated: 2023-07-18T07:34:32Z day: '01' doi: 10.1105/tpc.001248 extern: '1' external_id: pmid: - '12034894' intvolume: ' 14' issue: '5' language: - iso: eng main_file_link: - open_access: '1' url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC150604/ month: '05' oa: 1 oa_version: None page: 1017 - 1031 pmid: 1 publication: Plant Cell publication_identifier: issn: - 1040-4651 publication_status: published publisher: American Society of Plant Biologists publist_id: '3716' quality_controlled: '1' scopus_import: '1' status: public title: Hydra mutants of Arabidopsis are defective in sterol profiles and auxin and ethylene signaling type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 14 year: '2002' ... --- _id: '2866' abstract: - lang: eng text: 'Developmental responses to the plant hormone auxin are thought to be mediated by interacting pairs from two protein families: short-lived inhibitory IAA proteins and ARF transcription factors binding to auxin-response elements. Monopteros mutants lacking activating ARF5 and the auxin-insensitive mutant bodenlos fail to initiate the root meristem during early embryogenesis. Here we show that the bodenlos phenotype results from an amino-acid exchange in the conserved degradation domain of IAA12. BODENLOS and MONOPTEROS interact in the yeast two-hybrid assay and the two genes are coexpressed in early embryogenesis, suggesting that BODENLOS inhibits MONOPTEROS action in root meristem initiation.' acknowledgement: "We thank C. Maulbetsch for isolating BDL cDNA clones; T. Berleth and J. Friml for providing clones for in situ probes; K. Harter for making available the parsley protoplast system; and J. Friml, N. Geldner, M. Griffith, C. Schwechheimer, D. Weigel, and D. Weijers for helpful comments and critical reading of the manuscript. This work was supported by Sonderforschungsbereich 446 “Mechanismen des Zellverhaltens bei Eukaryoten.”\r\n\r\nThe publication costs of this article were defrayed in part by payment of page charges. This article must therefore be hereby marked “advertisement” in accordance with 18 USC section 1734 solely to indicate this fact." article_processing_charge: No article_type: original author: - first_name: Thorsten full_name: Hamann, Thorsten last_name: Hamann - first_name: Eva full_name: Benková, Eva id: 38F4F166-F248-11E8-B48F-1D18A9856A87 last_name: Benková orcid: 0000-0002-8510-9739 - first_name: Isabel full_name: Bäurle, Isabel last_name: Bäurle - first_name: Marika full_name: Kientz, Marika last_name: Kientz - first_name: Gerd full_name: Jürgens, Gerd last_name: Jürgens citation: ama: Hamann T, Benková E, Bäurle I, Kientz M, Jürgens G. The Arabidopsis BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated embryo patterning. Genes and Development. 2002;16(13):1610-1615. doi:10.1101/gad.229402 apa: Hamann, T., Benková, E., Bäurle, I., Kientz, M., & Jürgens, G. (2002). The Arabidopsis BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated embryo patterning. Genes and Development. Cold Spring Harbor Laboratory Press. https://doi.org/10.1101/gad.229402 chicago: Hamann, Thorsten, Eva Benková, Isabel Bäurle, Marika Kientz, and Gerd Jürgens. “The Arabidopsis BODENLOS Gene Encodes an Auxin Response Protein Inhibiting MONOPTEROS-Mediated Embryo Patterning.” Genes and Development. Cold Spring Harbor Laboratory Press, 2002. https://doi.org/10.1101/gad.229402. ieee: T. Hamann, E. Benková, I. Bäurle, M. Kientz, and G. Jürgens, “The Arabidopsis BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated embryo patterning,” Genes and Development, vol. 16, no. 13. Cold Spring Harbor Laboratory Press, pp. 1610–1615, 2002. ista: Hamann T, Benková E, Bäurle I, Kientz M, Jürgens G. 2002. The Arabidopsis BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated embryo patterning. Genes and Development. 16(13), 1610–1615. mla: Hamann, Thorsten, et al. “The Arabidopsis BODENLOS Gene Encodes an Auxin Response Protein Inhibiting MONOPTEROS-Mediated Embryo Patterning.” Genes and Development, vol. 16, no. 13, Cold Spring Harbor Laboratory Press, 2002, pp. 1610–15, doi:10.1101/gad.229402. short: T. Hamann, E. Benková, I. Bäurle, M. Kientz, G. Jürgens, Genes and Development 16 (2002) 1610–1615. date_created: 2018-12-11T12:00:01Z date_published: 2002-07-01T00:00:00Z date_updated: 2023-07-18T08:26:58Z day: '01' doi: 10.1101/gad.229402 extern: '1' external_id: pmid: - '12101120' intvolume: ' 16' issue: '13' language: - iso: eng main_file_link: - open_access: '1' url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC186366/ month: '07' oa: 1 oa_version: Published Version page: 1610 - 1615 pmid: 1 publication: Genes and Development publication_identifier: issn: - 0890-9369 publication_status: published publisher: Cold Spring Harbor Laboratory Press publist_id: '3921' quality_controlled: '1' scopus_import: '1' status: public title: The Arabidopsis BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated embryo patterning type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 16 year: '2002' ... --- _id: '2927' abstract: - lang: eng text: 'In the last few years, several new algorithms based on graph cuts have been developed to solve energy minimization problems in computer vision. Each of these techniques constructs a graph such that the minimum cut on the graph also minimizes the energy. Yet because these graph constructions are complex and highly specific to a particular energy function, graph cuts have seen limited application to date. In this paper we characterize the energy functions that can be minimized by graph cuts. Our results are restricted to energy functions with binary variables. However, our work generalizes many previous constructions, and is easily applicable to vision problems that involve large numbers of labels, such as stereo, motion, image restoration and scene reconstruction. We present three main results: a necessary condition for any energy function that can be minimized by graph cuts; a sufficient condition for energy functions that can be written as a sum of functions of up to three variables at a time; and a general-purpose construction to minimize such an energy function. Researchers who are considering the use of graph cuts to optimize a particular energy function can use our results to determine if this is possible, and then follow our construction to create the appropriate graph.' acknowledgement: We thank Olga Veksler and Yuri Boykov for their careful reading of this paper, and for valuable comments which greatly improved itsreadibility. We also thank Ian Jermyn for helping us clarify the paper’s motivation. This research was supported by NSF grants IIS-9900115 and CCR-0113371, and by a grant from Microsoft Research. article_processing_charge: No author: - first_name: Vladimir full_name: Kolmogorov, Vladimir id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87 last_name: Kolmogorov - first_name: Ramin full_name: Zabih, Ramin last_name: Zabih citation: ama: 'Kolmogorov V, Zabih R. Multi-camera scene reconstruction via graph cuts. In: Proceedings of the 7th European Conference on Computer Vision. Springer; 2002:65-81. doi:10.1007/3-540-47977-5_5' apa: 'Kolmogorov, V., & Zabih, R. (2002). Multi-camera scene reconstruction via graph cuts. In Proceedings of the 7th European Conference on Computer Vision (pp. 65–81). Copenhagen, Denmark: Springer. https://doi.org/10.1007/3-540-47977-5_5' chicago: Kolmogorov, Vladimir, and Ramin Zabih. “Multi-Camera Scene Reconstruction via Graph Cuts.” In Proceedings of the 7th European Conference on Computer Vision, 65–81. Springer, 2002. https://doi.org/10.1007/3-540-47977-5_5. ieee: V. Kolmogorov and R. Zabih, “Multi-camera scene reconstruction via graph cuts,” in Proceedings of the 7th European Conference on Computer Vision, Copenhagen, Denmark, 2002, pp. 65–81. ista: 'Kolmogorov V, Zabih R. 2002. Multi-camera scene reconstruction via graph cuts. Proceedings of the 7th European Conference on Computer Vision. ECCV: European Conference on Computer Vision, 65–81.' mla: Kolmogorov, Vladimir, and Ramin Zabih. “Multi-Camera Scene Reconstruction via Graph Cuts.” Proceedings of the 7th European Conference on Computer Vision, Springer, 2002, pp. 65–81, doi:10.1007/3-540-47977-5_5. short: V. Kolmogorov, R. Zabih, in:, Proceedings of the 7th European Conference on Computer Vision, Springer, 2002, pp. 65–81. conference: end_date: 2002-05-31 location: Copenhagen, Denmark name: 'ECCV: European Conference on Computer Vision' start_date: 2002-05-28 date_created: 2018-12-11T12:00:23Z date_published: 2002-01-01T00:00:00Z date_updated: 2023-07-18T08:20:02Z day: '01' doi: 10.1007/3-540-47977-5_5 extern: '1' language: - iso: eng month: '01' oa_version: None page: 65 - 81 publication: Proceedings of the 7th European Conference on Computer Vision publication_identifier: isbn: - '9783540437468' publication_status: published publisher: Springer publist_id: '3810' quality_controlled: '1' scopus_import: '1' status: public title: Multi-camera scene reconstruction via graph cuts type: conference user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 year: '2002' ... --- _id: '2739' abstract: - lang: eng text: We define the two dimensional Pauli operator and identify its core for magnetic fields that are regular Borel measures. The magnetic field is generated by a scalar potential hence we bypass the usual A L 2loc condition on the vector potential, which does not allow to consider such singular fields. We extend the Aharonov-Casher theorem for magnetic fields that are measures with finite total variation and we present a counterexample in case of infinite total variation. One of the key technical tools is a weighted L 2 estimate on a singular integral operator. acknowledgement: "This work started during the first author’s visit at the Erwin Schrödinger Institute, Vienna.\r\nValuable discussions with T. Hoffmann-Ostenhof and M. Loss are gratefully acknowledged. The authors thank\r\nthe referee for careful reading and comments" article_processing_charge: No article_type: original author: - first_name: László full_name: Erdös, László id: 4DBD5372-F248-11E8-B48F-1D18A9856A87 last_name: Erdös orcid: 0000-0001-5366-9603 - first_name: Vitali full_name: Vougalter, Vitali last_name: Vougalter citation: ama: Erdös L, Vougalter V. Pauli operator and Aharonov–Casher theorem¶ for measure valued magnetic fields. Communications in Mathematical Physics. 2002;225(2):399-421. doi:10.1007/s002200100585 apa: Erdös, L., & Vougalter, V. (2002). Pauli operator and Aharonov–Casher theorem¶ for measure valued magnetic fields. Communications in Mathematical Physics. Springer. https://doi.org/10.1007/s002200100585 chicago: Erdös, László, and Vitali Vougalter. “Pauli Operator and Aharonov–Casher Theorem¶ for Measure Valued Magnetic Fields.” Communications in Mathematical Physics. Springer, 2002. https://doi.org/10.1007/s002200100585. ieee: L. Erdös and V. Vougalter, “Pauli operator and Aharonov–Casher theorem¶ for measure valued magnetic fields,” Communications in Mathematical Physics, vol. 225, no. 2. Springer, pp. 399–421, 2002. ista: Erdös L, Vougalter V. 2002. Pauli operator and Aharonov–Casher theorem¶ for measure valued magnetic fields. Communications in Mathematical Physics. 225(2), 399–421. mla: Erdös, László, and Vitali Vougalter. “Pauli Operator and Aharonov–Casher Theorem¶ for Measure Valued Magnetic Fields.” Communications in Mathematical Physics, vol. 225, no. 2, Springer, 2002, pp. 399–421, doi:10.1007/s002200100585. short: L. Erdös, V. Vougalter, Communications in Mathematical Physics 225 (2002) 399–421. date_created: 2018-12-11T11:59:21Z date_published: 2002-02-01T00:00:00Z date_updated: 2023-07-18T08:57:54Z day: '01' doi: 10.1007/s002200100585 extern: '1' external_id: arxiv: - math-ph/0109015v1 intvolume: ' 225' issue: '2' language: - iso: eng month: '02' oa_version: None page: 399 - 421 publication: Communications in Mathematical Physics publication_identifier: issn: - 0010-3616 publication_status: published publisher: Springer publist_id: '4153' quality_controlled: '1' scopus_import: '1' status: public title: Pauli operator and Aharonov–Casher theorem¶ for measure valued magnetic fields type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 225 year: '2002' ... --- _id: '2738' abstract: - lang: eng text: We consider the long time evolution of a quantum particle weakly interacting with a phonon field. We show that in the weak coupling limit the Wigner distribution of the electron density matrix converges to the solution of the linear Boltzmann equation globally in time. The collision kernel is identified as the sum of an emission and an absorption term that depend on the equilibrium distribution of the free phonon modes. acknowledgement: "This work initially was a joint project with H.-T. Yau and several ideas\r\npresented here have been developed in collaboration with him. I would like\r\nto thank him for the invaluable discussions and encouragement through\r\nthe entire work. Part of this project was completed during several visits at\r\nthe Erwin Schrödinger Institute, Vienna, and at the Center of Theoretical\r\nStudies, Hsinchu, Taiwan. The author is grateful for the hospitality and\r\nfinancial support. This work was partially supported by NSF Grant DMS9970323." article_processing_charge: No article_type: original author: - first_name: László full_name: Erdös, László id: 4DBD5372-F248-11E8-B48F-1D18A9856A87 last_name: Erdös orcid: 0000-0001-5366-9603 citation: ama: Erdös L. Linear Boltzmann equation as the long time dynamics of an electron weakly coupled to a phonon field. Journal of Statistical Physics. 2002;107(5-6):1043-1127. doi:10.1023/A:1015157624384 apa: Erdös, L. (2002). Linear Boltzmann equation as the long time dynamics of an electron weakly coupled to a phonon field. Journal of Statistical Physics. Springer. https://doi.org/10.1023/A:1015157624384 chicago: Erdös, László. “Linear Boltzmann Equation as the Long Time Dynamics of an Electron Weakly Coupled to a Phonon Field.” Journal of Statistical Physics. Springer, 2002. https://doi.org/10.1023/A:1015157624384. ieee: L. Erdös, “Linear Boltzmann equation as the long time dynamics of an electron weakly coupled to a phonon field,” Journal of Statistical Physics, vol. 107, no. 5–6. Springer, pp. 1043–1127, 2002. ista: Erdös L. 2002. Linear Boltzmann equation as the long time dynamics of an electron weakly coupled to a phonon field. Journal of Statistical Physics. 107(5–6), 1043–1127. mla: Erdös, László. “Linear Boltzmann Equation as the Long Time Dynamics of an Electron Weakly Coupled to a Phonon Field.” Journal of Statistical Physics, vol. 107, no. 5–6, Springer, 2002, pp. 1043–127, doi:10.1023/A:1015157624384. short: L. Erdös, Journal of Statistical Physics 107 (2002) 1043–1127. date_created: 2018-12-11T11:59:20Z date_published: 2002-06-01T00:00:00Z date_updated: 2023-07-18T09:08:45Z day: '01' doi: 10.1023/A:1015157624384 extern: '1' external_id: arxiv: - math-ph/0108025 intvolume: ' 107' issue: 5-6 language: - iso: eng month: '06' oa_version: Submitted Version page: 1043 - 1127 publication: Journal of Statistical Physics publication_identifier: issn: - 0022-4715 publication_status: published publisher: Springer publist_id: '4154' quality_controlled: '1' scopus_import: '1' status: public title: Linear Boltzmann equation as the long time dynamics of an electron weakly coupled to a phonon field type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 107 year: '2002' ... --- _id: '2740' abstract: - lang: eng text: We show that the lowest eigenvalue of the magnetic Schrödinger operator on a line bundle over a compact Riemann surface M is bounded by the L1-norm of the magnetic field B. This implies a similar bound on the multiplicity of the ground state. An example shows that this degeneracy can indeed be comparable with ∫M |B| even in case of the trivial bundle. article_processing_charge: No article_type: original author: - first_name: László full_name: Erdös, László id: 4DBD5372-F248-11E8-B48F-1D18A9856A87 last_name: Erdös orcid: 0000-0001-5366-9603 citation: ama: Erdös L. Spectral shift and multiplicity of the first eigenvalue of the magnetic Schrödinger operator in two dimensions. Annales de l’Institut Fourier. 2002;52(6):1833-1874. doi:10.5802/aif.1936 apa: Erdös, L. (2002). Spectral shift and multiplicity of the first eigenvalue of the magnetic Schrödinger operator in two dimensions. Annales de l’Institut Fourier. Association des Annales de l’Institut Fourier. https://doi.org/10.5802/aif.1936 chicago: Erdös, László. “Spectral Shift and Multiplicity of the First Eigenvalue of the Magnetic Schrödinger Operator in Two Dimensions.” Annales de l’Institut Fourier. Association des Annales de l’Institut Fourier, 2002. https://doi.org/10.5802/aif.1936. ieee: L. Erdös, “Spectral shift and multiplicity of the first eigenvalue of the magnetic Schrödinger operator in two dimensions,” Annales de l’Institut Fourier, vol. 52, no. 6. Association des Annales de l’Institut Fourier, pp. 1833–1874, 2002. ista: Erdös L. 2002. Spectral shift and multiplicity of the first eigenvalue of the magnetic Schrödinger operator in two dimensions. Annales de l’Institut Fourier. 52(6), 1833–1874. mla: Erdös, László. “Spectral Shift and Multiplicity of the First Eigenvalue of the Magnetic Schrödinger Operator in Two Dimensions.” Annales de l’Institut Fourier, vol. 52, no. 6, Association des Annales de l’Institut Fourier, 2002, pp. 1833–74, doi:10.5802/aif.1936. short: L. Erdös, Annales de l’Institut Fourier 52 (2002) 1833–1874. date_created: 2018-12-11T11:59:21Z date_published: 2002-01-01T00:00:00Z date_updated: 2023-07-18T08:38:34Z day: '01' doi: 10.5802/aif.1936 extern: '1' intvolume: ' 52' issue: '6' language: - iso: eng month: '01' oa_version: None page: 1833-1874 publication: Annales de l'Institut Fourier publication_identifier: issn: - 0373-0956 publication_status: published publisher: Association des Annales de l'Institut Fourier publist_id: '4152' quality_controlled: '1' scopus_import: '1' status: public title: Spectral shift and multiplicity of the first eigenvalue of the magnetic Schrödinger operator in two dimensions type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 52 year: '2002' ... --- _id: '2737' abstract: - lang: eng text: We derive the time-dependent Schrödinger–Poisson equation as the weak coupling limit of the N-body linear Schrödinger equation with Coulomb potential. acknowledgement: "The authors thank the ESI in Vienna and the Austrian START project “Nonlinear Schrödinger\r\nand quantum Boltzmann equations” of N.J.M. for hospitality and support. Also, F.G. was supported by the Institut\r\nUniversitaire de France and N.J.M. by the bilateral Austrian-French “AMADEUS” programme. H.-T.Y. and L.E. were\r\nsupported by NSF Grants DMS-0072098 and DMS-9970323, respectively" article_processing_charge: No article_type: original author: - first_name: Claude full_name: Bardos, Claude last_name: Bardos - first_name: László full_name: Erdös, László id: 4DBD5372-F248-11E8-B48F-1D18A9856A87 last_name: Erdös orcid: 0000-0001-5366-9603 - first_name: François full_name: Golse, François last_name: Golse - first_name: Norbert full_name: Mauser, Norbert last_name: Mauser - first_name: Horng full_name: Yau, Horng last_name: Yau citation: ama: Bardos C, Erdös L, Golse F, Mauser N, Yau H. Derivation of the Schrödinger-Poisson equation from the quantum N-body problem. Comptes Rendus Mathematique. 2002;334(6):515-520. doi:10.1016/S1631-073X(02)02253-7 apa: Bardos, C., Erdös, L., Golse, F., Mauser, N., & Yau, H. (2002). Derivation of the Schrödinger-Poisson equation from the quantum N-body problem. Comptes Rendus Mathematique. Elsevier. https://doi.org/10.1016/S1631-073X(02)02253-7 chicago: Bardos, Claude, László Erdös, François Golse, Norbert Mauser, and Horng Yau. “Derivation of the Schrödinger-Poisson Equation from the Quantum N-Body Problem.” Comptes Rendus Mathematique. Elsevier, 2002. https://doi.org/10.1016/S1631-073X(02)02253-7. ieee: C. Bardos, L. Erdös, F. Golse, N. Mauser, and H. Yau, “Derivation of the Schrödinger-Poisson equation from the quantum N-body problem,” Comptes Rendus Mathematique, vol. 334, no. 6. Elsevier, pp. 515–520, 2002. ista: Bardos C, Erdös L, Golse F, Mauser N, Yau H. 2002. Derivation of the Schrödinger-Poisson equation from the quantum N-body problem. Comptes Rendus Mathematique. 334(6), 515–520. mla: Bardos, Claude, et al. “Derivation of the Schrödinger-Poisson Equation from the Quantum N-Body Problem.” Comptes Rendus Mathematique, vol. 334, no. 6, Elsevier, 2002, pp. 515–20, doi:10.1016/S1631-073X(02)02253-7. short: C. Bardos, L. Erdös, F. Golse, N. Mauser, H. Yau, Comptes Rendus Mathematique 334 (2002) 515–520. date_created: 2018-12-11T11:59:20Z date_published: 2002-03-30T00:00:00Z date_updated: 2023-07-18T09:24:24Z day: '30' doi: 10.1016/S1631-073X(02)02253-7 extern: '1' intvolume: ' 334' issue: '6' language: - iso: eng month: '03' oa_version: None page: 515 - 520 publication: Comptes Rendus Mathematique publication_identifier: issn: - 1631-073X publication_status: published publisher: Elsevier publist_id: '4155' quality_controlled: '1' scopus_import: '1' status: public title: Derivation of the Schrödinger-Poisson equation from the quantum N-body problem type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 334 year: '2002' ... --- _id: '2624' abstract: - lang: eng text: Metabotropic γ-aminobutyric acid receptors (GABABRs) are involved in modulation of synaptic transmission and activity of cerebellar and thalamic neurons. We used subtype-specific antibodies in pre- and postembedding immunohistochemistry combined with three-dimensional reconstruction of labelled profiles and quantification of immunoparticles to reveal the subcellular distribution of pre- and postsynaptic GABABR1a/b and GABABR2 in the rat cerebellum and ventrobasal thalamus. GABABR1a/b and R2 were extensively colocalized in most brain regions including the cerebellum and thalamus. In the cerebellum, immunoreactivity for both subtypes was prevalent in the molecular layer. The most intense immunoreactivity was found in Purkinje cell spines with a high density of immunoparticles at extrasynaptic sites peaking at around 240 nm from glutamatergic synapses between spines and parallel fibre varicosities. This is in contrast to dendrites at sites around GABAergic synapses where sparse and random distribution was found for both subtypes. In addition, more than one-tenth of the synaptic membrane specialization of spine-parallel fibre synapses were labelled at pre- or postsynaptic sites. Weak immunolabelling for both subtypes was also seen in parallel fibres but only rarely in GABAergic axons. In the ventrobasal thalamus, immunolabelling for both receptor subtypes was intense over the dendritic field of thalamocortical cells. Electron microscopy demonstrated an extrasynaptic localization of GABABR1a/b and R2 exclusively in postsynaptic elements. Quantitative analysis further revealed the density of GABABR1a/b around GABAergic synapses was higher than glutamatergic synapses on thalamocortical cell dendrites. The distinct localization of GABABRs relative to synaptic sites in the cerebellum and ventrobasal thalamus suggests that GABABRs differentially regulate activity of different neuronal populations. acknowledgement: This work was supported by research grants from the Ministry of Education, Science, Sports and Culture of Japan, and the Japan Society for the Promotion of Science (P96319). We thank Drs L. Zaborszky and R. Luján for their comments on the manuscript, Dr M. Watanabe for kindly supplying us with GluRδ2 and AMPA GluR1 antibodies, Dr R.E. Edwards for rabbit BNPI antibody, and J. Hatakeyama and S. Doi for technical assistance. article_processing_charge: No article_type: original author: - first_name: Ákos full_name: Kulik, Ákos last_name: Kulik - first_name: Kazuhiko full_name: Nakadate, Kazuhiko last_name: Nakadate - first_name: Gábor full_name: Nyíri, Gábor last_name: Nyíri - first_name: Takuya full_name: Notomi, Takuya last_name: Notomi - first_name: Barbara full_name: Malitschek, Barbara last_name: Malitschek - first_name: Bernhard full_name: Bettler, Bernhard last_name: Bettler - first_name: Ryuichi full_name: Shigemoto, Ryuichi id: 499F3ABC-F248-11E8-B48F-1D18A9856A87 last_name: Shigemoto orcid: 0000-0001-8761-9444 citation: ama: Kulik Á, Nakadate K, Nyíri G, et al. Distinct localization of GABAB receptors relative to synaptic sites in the rat cerebellum and ventrobasal thalamus. European Journal of Neuroscience. 2002;15(2):291-307. doi:10.1046/j.0953-816x.2001.01855.x apa: Kulik, Á., Nakadate, K., Nyíri, G., Notomi, T., Malitschek, B., Bettler, B., & Shigemoto, R. (2002). Distinct localization of GABAB receptors relative to synaptic sites in the rat cerebellum and ventrobasal thalamus. European Journal of Neuroscience. Wiley-Blackwell. https://doi.org/10.1046/j.0953-816x.2001.01855.x chicago: Kulik, Ákos, Kazuhiko Nakadate, Gábor Nyíri, Takuya Notomi, Barbara Malitschek, Bernhard Bettler, and Ryuichi Shigemoto. “Distinct Localization of GABAB Receptors Relative to Synaptic Sites in the Rat Cerebellum and Ventrobasal Thalamus.” European Journal of Neuroscience. Wiley-Blackwell, 2002. https://doi.org/10.1046/j.0953-816x.2001.01855.x. ieee: Á. Kulik et al., “Distinct localization of GABAB receptors relative to synaptic sites in the rat cerebellum and ventrobasal thalamus,” European Journal of Neuroscience, vol. 15, no. 2. Wiley-Blackwell, pp. 291–307, 2002. ista: Kulik Á, Nakadate K, Nyíri G, Notomi T, Malitschek B, Bettler B, Shigemoto R. 2002. Distinct localization of GABAB receptors relative to synaptic sites in the rat cerebellum and ventrobasal thalamus. European Journal of Neuroscience. 15(2), 291–307. mla: Kulik, Ákos, et al. “Distinct Localization of GABAB Receptors Relative to Synaptic Sites in the Rat Cerebellum and Ventrobasal Thalamus.” European Journal of Neuroscience, vol. 15, no. 2, Wiley-Blackwell, 2002, pp. 291–307, doi:10.1046/j.0953-816x.2001.01855.x. short: Á. Kulik, K. Nakadate, G. Nyíri, T. Notomi, B. Malitschek, B. Bettler, R. Shigemoto, European Journal of Neuroscience 15 (2002) 291–307. date_created: 2018-12-11T11:58:44Z date_published: 2002-01-01T00:00:00Z date_updated: 2023-07-18T13:08:40Z day: '01' doi: 10.1046/j.0953-816x.2001.01855.x extern: '1' external_id: pmid: - '11849296' intvolume: ' 15' issue: '2' language: - iso: eng month: '01' oa_version: None page: 291 - 307 pmid: 1 publication: European Journal of Neuroscience publication_identifier: issn: - 0953-816X publication_status: published publisher: Wiley-Blackwell publist_id: '4275' quality_controlled: '1' scopus_import: '1' status: public title: Distinct localization of GABAB receptors relative to synaptic sites in the rat cerebellum and ventrobasal thalamus type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 15 year: '2002' ... --- _id: '2694' abstract: - lang: eng text: We outline the status of rigorous derivations of certain classical evolution equations as limits of Schrödinger dynamics. We explain two recent results jointly with H.T. Yau in more details. The first one is the derivation of the linear Boltzmann equation as the long time limit of the one-body Schrödinger equation with a random potential. The second one is the mean field limit of high density bosons with Coulomb interaction that leads to the nonlinear Hartree equation. alternative_title: - LNP article_processing_charge: No author: - first_name: László full_name: Erdös, László id: 4DBD5372-F248-11E8-B48F-1D18A9856A87 last_name: Erdös orcid: 0000-0001-5366-9603 citation: ama: 'Erdös L. Scaling limits of Schrödinger quantum mechanics. In: Dynamics of Dissipation. Lecture Notes in Physics. Springer; 2002:487-506. doi:10.1007/3-540-46122-1_19' apa: Erdös, L. (2002). Scaling limits of Schrödinger quantum mechanics. In Dynamics of Dissipation (pp. 487–506). Springer. https://doi.org/10.1007/3-540-46122-1_19 chicago: Erdös, László. “Scaling Limits of Schrödinger Quantum Mechanics.” In Dynamics of Dissipation, 487–506. Lecture Notes in Physics. Springer, 2002. https://doi.org/10.1007/3-540-46122-1_19. ieee: L. Erdös, “Scaling limits of Schrödinger quantum mechanics,” in Dynamics of Dissipation, Springer, 2002, pp. 487–506. ista: 'Erdös L. 2002.Scaling limits of Schrödinger quantum mechanics. In: Dynamics of Dissipation. LNP, , 487–506.' mla: Erdös, László. “Scaling Limits of Schrödinger Quantum Mechanics.” Dynamics of Dissipation, Springer, 2002, pp. 487–506, doi:10.1007/3-540-46122-1_19. short: L. Erdös, in:, Dynamics of Dissipation, Springer, 2002, pp. 487–506. conference: name: '38th Winter School of Theoretical Physics : Dynamical Semigroups: Dissipation, Chaos, Quanta' date_created: 2018-12-11T11:59:06Z date_published: 2002-01-01T00:00:00Z date_updated: 2023-07-18T10:23:18Z day: '01' doi: 10.1007/3-540-46122-1_19 extern: '1' language: - iso: eng month: '01' oa_version: None page: 487 - 506 publication: Dynamics of Dissipation publication_identifier: isbn: - '9783540441113' publication_status: published publisher: Springer publist_id: '4203' quality_controlled: '1' series_title: Lecture Notes in Physics status: public title: Scaling limits of Schrödinger quantum mechanics type: book_chapter user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 year: '2002' ... --- _id: '2622' abstract: - lang: eng text: To understand the possible contribution of metabotropic γ-aminobutyric acid receptors (GABABR) in cortical development, we investigated the expression pattern and the cellular and subcellular localization of the GABABR1 and GABABR2 subtypes in the rat neocortex from embryonic day 14 (E14) to adulthood. At the light microscopic level, both GABABR1 and GABABR2 were detected as early as E14. During prenatal development, both subtypes were expressed highly in the cortical plate. Using double immunofluorescence, GABABR1 colocalized with GABABR2 in neurons of the marginal zone and subplate, indicating that these proteins are coexpressed and could be forming functional GABABRs during prenatal development in vivo. In contrast, only GABABR1 but not GABABR2 was detected in the tangentially migratory cells in the lower intermediate zone. During postnatal development, immunoreactivity for GABABR1 and GABABR2 was distributed mainly in pyramidal cells. Discrete GABABR1-immunopositive cell bodies of interneurons were present throughout the neocortex. In addition, GABABR1 but not GABABR2 was found in identified Cajal-Retzius cells in layer I. At the electron microscopic level, immunoreactivity for GABABR1 and GABABR2 was found in dendritic spines and dendritic shafts at extrasynaptic and perisynaptic sites throughout postnatal development. We further demonstrated the presynaptic localization of GABABR1 and GABABR2, as well as the association of the receptors with asymmetrical synaptic junctions. These results indicate potentially important roles for the GABABRs in the regulation of migratory processes during corticogenesis and in the modulation of synaptic transmission during early development of cortical circuitry. acknowledgement: The authors are grateful to Dr Marco Sassoe-Pogneto for his comments on a previous version of the manuscript. We also would like to thank to Ms. Courtney Voelker for the English revision and comments of the manuscript. This work was made possible by grants from the European Community (QLG3-CT-1999–00192, R.L) and the Spanish Ministry of Science and Technology (PB97-0582-CO2-01, A.F). article_processing_charge: No article_type: original author: - first_name: Guillermina full_name: López Bendito, Guillermina last_name: López Bendito - first_name: Ryuichi full_name: Shigemoto, Ryuichi id: 499F3ABC-F248-11E8-B48F-1D18A9856A87 last_name: Shigemoto orcid: 0000-0001-8761-9444 - first_name: Ákos full_name: Kulik, Ákos last_name: Kulik - first_name: Ole full_name: Paulsen, Ole last_name: Paulsen - first_name: Alfonso full_name: Fairén, Alfonso last_name: Fairén - first_name: Rafael full_name: Luján, Rafael last_name: Luján citation: ama: López Bendito G, Shigemoto R, Kulik Á, Paulsen O, Fairén A, Luján R. Expression and distribution of metabotropic GABA receptor subtypes GABABR1 and GABABR2 during rat neocortical development. European Journal of Neuroscience. 2002;15(11):1766-1778. doi:10.1046/j.1460-9568.2002.02032.x apa: López Bendito, G., Shigemoto, R., Kulik, Á., Paulsen, O., Fairén, A., & Luján, R. (2002). Expression and distribution of metabotropic GABA receptor subtypes GABABR1 and GABABR2 during rat neocortical development. European Journal of Neuroscience. Wiley-Blackwell. https://doi.org/10.1046/j.1460-9568.2002.02032.x chicago: López Bendito, Guillermina, Ryuichi Shigemoto, Ákos Kulik, Ole Paulsen, Alfonso Fairén, and Rafael Luján. “Expression and Distribution of Metabotropic GABA Receptor Subtypes GABABR1 and GABABR2 during Rat Neocortical Development.” European Journal of Neuroscience. Wiley-Blackwell, 2002. https://doi.org/10.1046/j.1460-9568.2002.02032.x. ieee: G. López Bendito, R. Shigemoto, Á. Kulik, O. Paulsen, A. Fairén, and R. Luján, “Expression and distribution of metabotropic GABA receptor subtypes GABABR1 and GABABR2 during rat neocortical development,” European Journal of Neuroscience, vol. 15, no. 11. Wiley-Blackwell, pp. 1766–1778, 2002. ista: López Bendito G, Shigemoto R, Kulik Á, Paulsen O, Fairén A, Luján R. 2002. Expression and distribution of metabotropic GABA receptor subtypes GABABR1 and GABABR2 during rat neocortical development. European Journal of Neuroscience. 15(11), 1766–1778. mla: López Bendito, Guillermina, et al. “Expression and Distribution of Metabotropic GABA Receptor Subtypes GABABR1 and GABABR2 during Rat Neocortical Development.” European Journal of Neuroscience, vol. 15, no. 11, Wiley-Blackwell, 2002, pp. 1766–78, doi:10.1046/j.1460-9568.2002.02032.x. short: G. López Bendito, R. Shigemoto, Á. Kulik, O. Paulsen, A. Fairén, R. Luján, European Journal of Neuroscience 15 (2002) 1766–1778. date_created: 2018-12-11T11:58:43Z date_published: 2002-06-01T00:00:00Z date_updated: 2023-07-19T07:30:39Z day: '01' doi: 10.1046/j.1460-9568.2002.02032.x extern: '1' external_id: pmid: - '12081656' intvolume: ' 15' issue: '11' language: - iso: eng month: '06' oa_version: None page: 1766 - 1778 pmid: 1 publication: European Journal of Neuroscience publication_identifier: issn: - 0953-816X publication_status: published publisher: Wiley-Blackwell publist_id: '4276' quality_controlled: '1' scopus_import: '1' status: public title: Expression and distribution of metabotropic GABA receptor subtypes GABABR1 and GABABR2 during rat neocortical development type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 15 year: '2002' ...