---
_id: '3673'
abstract:
- lang: eng
text: The effect of a cline as a barrier to gene flow at closely linked, weakly
selected loci is investigated using a continuous diffusion model. It is shown
that a linked cline induces a step in the frequency of a neutral allele, which
is proportional to the gradient in neutral allele frequency and to the inverse
of the recombination rate. A barrier to dispersal or a local region of low abundance
has a similar effect (Nagylaki, 1976). The cline will block the flow of neutral
alleles over a region of chromosome roughly 2s/t map units long. However, a slightly
advantageous allele will be little affected, and must be very tightly linked to
be delayed for long.
acknowledgement: "I would like to thank Dr G. M. Hewitt for stimulating discussions,
and for his comments on the manuscript. This work was supported by the Natural Environmental
Research Council.\r\n"
article_processing_charge: No
article_type: original
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Barton NH. Gene flow past a cline. Heredity. 1979;43(3):333-339. doi:10.1038/hdy.1979.86
apa: Barton, N. H. (1979). Gene flow past a cline. Heredity. Springer Nature.
https://doi.org/10.1038/hdy.1979.86
chicago: Barton, Nicholas H. “Gene Flow Past a Cline.” Heredity. Springer
Nature, 1979. https://doi.org/10.1038/hdy.1979.86.
ieee: N. H. Barton, “Gene flow past a cline,” Heredity, vol. 43, no. 3. Springer
Nature, pp. 333–339, 1979.
ista: Barton NH. 1979. Gene flow past a cline. Heredity. 43(3), 333–339.
mla: Barton, Nicholas H. “Gene Flow Past a Cline.” Heredity, vol. 43, no.
3, Springer Nature, 1979, pp. 333–39, doi:10.1038/hdy.1979.86.
short: N.H. Barton, Heredity 43 (1979) 333–339.
date_created: 2018-12-11T12:04:33Z
date_published: 1979-12-01T00:00:00Z
date_updated: 2021-12-15T15:16:50Z
day: '01'
doi: 10.1038/hdy.1979.86
extern: '1'
intvolume: ' 43'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.nature.com/articles/hdy197986
month: '12'
oa: 1
oa_version: Published Version
page: 333 - 339
publication: Heredity
publication_identifier:
eissn:
- 1365-2540
issn:
- 0018-067X
publication_status: published
publisher: Springer Nature
publist_id: '2710'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Gene flow past a cline
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 43
year: '1979'
...
---
_id: '4336'
abstract:
- lang: eng
text: "This paper investigates the dynamic behaviour of hybrid zones which are maintained
by a balance between dispersal and selection against hybrids. In the first section
it is shown that a hybrid zone involving a single locus can move in response to
a selective imbalance between the two homozygotes, and also to variation in population
density and dispersal rate. It can be trapped by natural barriers, and so an allele
which is selected against when rare cannot advance, even if it is advantageous
when common. The continuous model used in deriving these results is shown to be
a good approximation to the stepping-stone model, provided that the cline contains
several demes.\r\n\r\nThe effect of stochastic forces on multi-locus hybrid zones
is then considered. An expression giving the shift in position after an arbitrary
perturbation in gamete frequency is derived. Using this formula, it is found that
sampling drift is negligible unless the zone includes few organisms and involves
few loci. Random variations in population structure are the dominant force, and
could allow considerable movement in an even environment. However, natural barriers
can still trap hybrid zones, and so it is likely that they will remain roughly
where they first formed."
article_processing_charge: No
article_type: original
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Barton NH. The dynamics of hybrid zones. Heredity. 1979;43(3):341-359.
doi:10.1038/hdy.1979.87
apa: Barton, N. H. (1979). The dynamics of hybrid zones. Heredity. Springer
Nature. https://doi.org/10.1038/hdy.1979.87
chicago: Barton, Nicholas H. “The Dynamics of Hybrid Zones.” Heredity. Springer
Nature, 1979. https://doi.org/10.1038/hdy.1979.87.
ieee: N. H. Barton, “The dynamics of hybrid zones,” Heredity, vol. 43, no.
3. Springer Nature, pp. 341–359, 1979.
ista: Barton NH. 1979. The dynamics of hybrid zones. Heredity. 43(3), 341–359.
mla: Barton, Nicholas H. “The Dynamics of Hybrid Zones.” Heredity, vol. 43,
no. 3, Springer Nature, 1979, pp. 341–59, doi:10.1038/hdy.1979.87.
short: N.H. Barton, Heredity 43 (1979) 341–359.
date_created: 2018-12-11T12:08:19Z
date_published: 1979-12-01T00:00:00Z
date_updated: 2021-12-15T09:29:59Z
day: '01'
doi: 10.1038/hdy.1979.87
extern: '1'
intvolume: ' 43'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.nature.com/articles/hdy197987
month: '12'
oa: 1
oa_version: Published Version
page: 341 - 359
publication: Heredity
publication_identifier:
eissn:
- 1365-2540
issn:
- 0018-067X
publication_status: published
publisher: Springer Nature
publist_id: '1696'
quality_controlled: '1'
status: public
title: The dynamics of hybrid zones
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 43
year: '1979'
...
---
_id: '4337'
article_processing_charge: No
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Barton NH. A hybrid zone in the alpine grasshopper Podisma pedestris. 1979.
apa: Barton, N. H. (1979). A hybrid zone in the alpine grasshopper Podisma pedestris.
University of East Anglia.
chicago: Barton, Nicholas H. “A Hybrid Zone in the Alpine Grasshopper Podisma Pedestris.”
University of East Anglia, 1979.
ieee: N. H. Barton, “A hybrid zone in the alpine grasshopper Podisma pedestris,”
University of East Anglia, 1979.
ista: Barton NH. 1979. A hybrid zone in the alpine grasshopper Podisma pedestris.
University of East Anglia.
mla: Barton, Nicholas H. A Hybrid Zone in the Alpine Grasshopper Podisma Pedestris.
University of East Anglia, 1979.
short: N.H. Barton, A Hybrid Zone in the Alpine Grasshopper Podisma Pedestris, University
of East Anglia, 1979.
date_created: 2018-12-11T12:08:20Z
date_published: 1979-01-01T00:00:00Z
date_updated: 2021-12-16T08:04:16Z
day: '01'
degree_awarded: PhD
extern: '1'
language:
- iso: eng
month: '01'
oa_version: None
publication_status: published
publisher: University of East Anglia
publist_id: '1694'
status: public
title: A hybrid zone in the alpine grasshopper Podisma pedestris
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '1979'
...