---
_id: '2840'
abstract:
- lang: eng
text: It is known that the entorhinal cortex plays a crucial role in spatial cognition
in rodents. Neuroanatomical and electrophysiological data suggest that there is
a functional distinction between 2 subregions within the entorhinal cortex, the
medial entorhinal cortex (MEC), and the lateral entorhinal cortex (LEC). Rats
with MEC or LEC lesions were trained in 2 navigation tasks requiring allothetic
(water maze task) or idiothetic (path integration) information processing and
2-object exploration tasks allowing testing of spatial and nonspatial processing
of intramaze objects. MEC lesions mildly affected place navigation in the water
maze and produced a path integration deficit. They also altered the processing
of spatial information in both exploration tasks while sparing the processing
of nonspatial information. LEC lesions did not affect navigation abilities in
both the water maze and the path integration tasks. They altered spatial and nonspatial
processing in the object exploration task but not in the one-trial recognition
task. Overall, these results indicate that the MEC is important for spatial processing
and path integration. The LEC has some influence on both spatial and nonspatial
processes, suggesting that the 2 kinds of information interact at the level of
the EC.
author:
- first_name: Tiffany
full_name: Van Cauter, Tiffany
last_name: Van Cauter
- first_name: Jeremy
full_name: Camon, Jeremy
last_name: Camon
- first_name: Alice
full_name: Alvernhe, Alice
id: 467FB3D4-F248-11E8-B48F-1D18A9856A87
last_name: Alvernhe
- first_name: Coralie
full_name: Elduayen, Coralie
last_name: Elduayen
- first_name: Francesca
full_name: Sargolini, Francesca
last_name: Sargolini
- first_name: Étienne
full_name: Save, Étienne
last_name: Save
citation:
ama: Van Cauter T, Camon J, Alvernhe A, Elduayen C, Sargolini F, Save É. Distinct
roles of medial and lateral entorhinal cortex in spatial cognition. Cerebral
Cortex. 2013;23(2):451-459. doi:10.1093/cercor/bhs033
apa: Van Cauter, T., Camon, J., Alvernhe, A., Elduayen, C., Sargolini, F., &
Save, É. (2013). Distinct roles of medial and lateral entorhinal cortex in spatial
cognition. Cerebral Cortex. Oxford University Press. https://doi.org/10.1093/cercor/bhs033
chicago: Van Cauter, Tiffany, Jeremy Camon, Alice Alvernhe, Coralie Elduayen, Francesca
Sargolini, and Étienne Save. “Distinct Roles of Medial and Lateral Entorhinal
Cortex in Spatial Cognition.” Cerebral Cortex. Oxford University Press,
2013. https://doi.org/10.1093/cercor/bhs033.
ieee: T. Van Cauter, J. Camon, A. Alvernhe, C. Elduayen, F. Sargolini, and É. Save,
“Distinct roles of medial and lateral entorhinal cortex in spatial cognition,”
Cerebral Cortex, vol. 23, no. 2. Oxford University Press, pp. 451–459,
2013.
ista: Van Cauter T, Camon J, Alvernhe A, Elduayen C, Sargolini F, Save É. 2013.
Distinct roles of medial and lateral entorhinal cortex in spatial cognition. Cerebral
Cortex. 23(2), 451–459.
mla: Van Cauter, Tiffany, et al. “Distinct Roles of Medial and Lateral Entorhinal
Cortex in Spatial Cognition.” Cerebral Cortex, vol. 23, no. 2, Oxford University
Press, 2013, pp. 451–59, doi:10.1093/cercor/bhs033.
short: T. Van Cauter, J. Camon, A. Alvernhe, C. Elduayen, F. Sargolini, É. Save,
Cerebral Cortex 23 (2013) 451–459.
date_created: 2018-12-11T11:59:52Z
date_published: 2013-02-01T00:00:00Z
date_updated: 2021-01-12T07:00:08Z
day: '01'
department:
- _id: JoCs
doi: 10.1093/cercor/bhs033
intvolume: ' 23'
issue: '2'
language:
- iso: eng
month: '02'
oa_version: None
page: 451 - 459
publication: Cerebral Cortex
publication_status: published
publisher: Oxford University Press
publist_id: '3958'
quality_controlled: '1'
scopus_import: 1
status: public
title: Distinct roles of medial and lateral entorhinal cortex in spatial cognition
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 23
year: '2013'
...