--- _id: '10699' abstract: - lang: eng text: This is the third of three talks describing the observation and characterization of a ferromagnetic moiré heterostructure based on twisted bilayer graphene aligned to hexagonal boron nitride. In this segment I will present scanning probe magnetometry data acquired using a nanoSQUID-on-tip microscope, which provides ~150 nm spatial resolution and a field sensitivity of ~10 nT/rtHz. We study the distribution of magnetic domains within the device as a function of density, magnetic field training, and DC current. Our data allow us to constrain the magnitude of the orbital magnetic moment of the electrons in the QAH state. Comparison with simultaneously acquired transport data allows us to precisely correlate single domain dynamics with discrete jumps in the observed anomalous Hall signal. acknowledgement: I would like to thank the MURI program, Sloan foundation, AFOSR, and ARO for their generous support of this work. I would also like to thank the NSF GRFP and the Hertz foundation for their generous support of my graduate studies. alternative_title: - Bulletin of the American Physical Society article_number: B59.00013 article_processing_charge: No author: - first_name: Charles full_name: Tschirhart, Charles last_name: Tschirhart - first_name: Marec full_name: Serlin, Marec last_name: Serlin - first_name: Hryhoriy full_name: Polshyn, Hryhoriy id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48 last_name: Polshyn orcid: 0000-0001-8223-8896 - first_name: Yuxuan full_name: Zhang, Yuxuan last_name: Zhang - first_name: Jiacheng full_name: Zhu, Jiacheng last_name: Zhu - first_name: Leon full_name: Balents, Leon last_name: Balents - first_name: Martin E. full_name: Huber, Martin E. last_name: Huber - first_name: Kenji full_name: Watanabe, Kenji last_name: Watanabe - first_name: Takashi full_name: Tanaguchi, Takashi last_name: Tanaguchi - first_name: Andrea full_name: Young, Andrea last_name: Young citation: ama: 'Tschirhart C, Serlin M, Polshyn H, et al. Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part III: Scanning probe magnetometry. In: APS March Meeting 2020. Vol 65. American Physical Society; 2020.' apa: 'Tschirhart, C., Serlin, M., Polshyn, H., Zhang, Y., Zhu, J., Balents, L., … Young, A. (2020). Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part III: Scanning probe magnetometry. In APS March Meeting 2020 (Vol. 65). Denver, CO, United States: American Physical Society.' chicago: 'Tschirhart, Charles, Marec Serlin, Hryhoriy Polshyn, Yuxuan Zhang, Jiacheng Zhu, Leon Balents, Martin E. Huber, Kenji Watanabe, Takashi Tanaguchi, and Andrea Young. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure, Part III: Scanning Probe Magnetometry.” In APS March Meeting 2020, Vol. 65. American Physical Society, 2020.' ieee: 'C. Tschirhart et al., “Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part III: Scanning probe magnetometry,” in APS March Meeting 2020, Denver, CO, United States, 2020, vol. 65, no. 1.' ista: 'Tschirhart C, Serlin M, Polshyn H, Zhang Y, Zhu J, Balents L, Huber ME, Watanabe K, Tanaguchi T, Young A. 2020. Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part III: Scanning probe magnetometry. APS March Meeting 2020. APS: American Physical Society, Bulletin of the American Physical Society, vol. 65, B59.00013.' mla: 'Tschirhart, Charles, et al. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure, Part III: Scanning Probe Magnetometry.” APS March Meeting 2020, vol. 65, no. 1, B59.00013, American Physical Society, 2020.' short: C. Tschirhart, M. Serlin, H. Polshyn, Y. Zhang, J. Zhu, L. Balents, M.E. Huber, K. Watanabe, T. Tanaguchi, A. Young, in:, APS March Meeting 2020, American Physical Society, 2020. conference: end_date: 2020-03-06 location: Denver, CO, United States name: 'APS: American Physical Society' start_date: 2020-03-02 date_created: 2022-01-28T10:57:49Z date_published: 2020-03-01T00:00:00Z date_updated: 2023-02-21T15:57:52Z day: '01' extern: '1' external_id: arxiv: - '1907.00261' intvolume: ' 65' issue: '1' language: - iso: eng main_file_link: - open_access: '1' url: https://meetings.aps.org/Meeting/MAR20/Session/B59.13 month: '03' oa: 1 oa_version: Published Version publication: APS March Meeting 2020 publication_identifier: issn: - 0003-0503 publication_status: published publisher: American Physical Society quality_controlled: '1' related_material: record: - id: '10619' relation: other status: public status: public title: 'Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part III: Scanning probe magnetometry' type: conference user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9 volume: 65 year: '2020' ... --- _id: '10697' abstract: - lang: eng text: We report the observation of a quantized anomalous Hall effect in a moiré heterostructure consisting of twisted bilayer graphene aligned to an encapsulating hBN substrate. The effect occurs at a density of 3 electrons per superlattice unit cell, where we observe magnetic hysteresis and a Hall resistance quantized to within 0.1% of the resistance quantum at temperatures as high as 3K. In this first of 3 talks, I will describe the fabrication procedure for our device as well as basic transport characterization measurements. I will introduce the phenomenology of twisted bilayer graphene and present evidence for hBN alignment as manifested in the hierarchy of symmetry-breaking gaps and anomalous magnetoresistance. acknowledgement: I would like to thank the MURI program, Sloan foundation, AFOSR, and ARO for their generous support of this work. alternative_title: - Bulletin of the American Physical Society article_number: B59.00012 article_processing_charge: No author: - first_name: Yuxuan full_name: Zhang, Yuxuan last_name: Zhang - first_name: Marec full_name: Serlin, Marec last_name: Serlin - first_name: Charles full_name: Tschirhart, Charles last_name: Tschirhart - first_name: Hryhoriy full_name: Polshyn, Hryhoriy id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48 last_name: Polshyn orcid: 0000-0001-8223-8896 - first_name: Jiacheng full_name: Zhu, Jiacheng last_name: Zhu - first_name: Leon full_name: Balents, Leon last_name: Balents - first_name: Martin E. full_name: Huber, Martin E. last_name: Huber - first_name: Takashi full_name: Taniguchi, Takashi last_name: Taniguchi - first_name: Kenji full_name: Watanabe, Kenji last_name: Watanabe - first_name: Andrea full_name: Young, Andrea last_name: Young citation: ama: 'Zhang Y, Serlin M, Tschirhart C, et al. Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part I: Device fabrication and transport. In: APS March Meeting 2020. Vol 65. American Physical Society; 2020.' apa: 'Zhang, Y., Serlin, M., Tschirhart, C., Polshyn, H., Zhu, J., Balents, L., … Young, A. (2020). Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part I: Device fabrication and transport. In APS March Meeting 2020 (Vol. 65). Denver, CO, United States: American Physical Society.' chicago: 'Zhang, Yuxuan, Marec Serlin, Charles Tschirhart, Hryhoriy Polshyn, Jiacheng Zhu, Leon Balents, Martin E. Huber, Takashi Taniguchi, Kenji Watanabe, and Andrea Young. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure, Part I: Device Fabrication and Transport.” In APS March Meeting 2020, Vol. 65. American Physical Society, 2020.' ieee: 'Y. Zhang et al., “Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part I: Device fabrication and transport,” in APS March Meeting 2020, Denver, CO, United States, 2020, vol. 65, no. 1.' ista: 'Zhang Y, Serlin M, Tschirhart C, Polshyn H, Zhu J, Balents L, Huber ME, Taniguchi T, Watanabe K, Young A. 2020. Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part I: Device fabrication and transport. APS March Meeting 2020. APS: American Physical Society, Bulletin of the American Physical Society, vol. 65, B59.00012.' mla: 'Zhang, Yuxuan, et al. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure, Part I: Device Fabrication and Transport.” APS March Meeting 2020, vol. 65, no. 1, B59.00012, American Physical Society, 2020.' short: Y. Zhang, M. Serlin, C. Tschirhart, H. Polshyn, J. Zhu, L. Balents, M.E. Huber, T. Taniguchi, K. Watanabe, A. Young, in:, APS March Meeting 2020, American Physical Society, 2020. conference: end_date: 2020-03-06 location: Denver, CO, United States name: 'APS: American Physical Society' start_date: 2020-03-02 date_created: 2022-01-28T10:28:35Z date_published: 2020-03-01T00:00:00Z date_updated: 2023-02-21T15:57:52Z day: '01' extern: '1' external_id: arxiv: - '1907.00261' intvolume: ' 65' issue: '1' language: - iso: eng main_file_link: - open_access: '1' url: https://meetings.aps.org/Meeting/MAR20/Session/B59.12 month: '03' oa: 1 oa_version: Published Version publication: APS March Meeting 2020 publication_status: published publisher: American Physical Society quality_controlled: '1' related_material: record: - id: '10619' relation: other status: public status: public title: 'Intrinsic quantized anomalous Hall effect in a moiré heterostructure, part I: Device fabrication and transport' type: conference user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9 volume: 65 year: '2020' ... --- _id: '10696' abstract: - lang: eng text: We experimentally investigate twisted van der Waals heterostructures of monolayer graphene rotated with respect to a bernal stacked graphene bilayer. We report transport measurements for devices with twist angles between 0.9 and 1.4°. The electric field allows efficient tuning of the width, isolation and the topology of the moiré bands in this system. By comparing magnetoresistance measurements to numerical simulations, we develop an understanding of the band structure. Finally, we observe correlated states at half- and quarter-fillings, which arise when narrow moire sublattice band is isolated by energy gaps from dispersive bands. We investigate the effects of in-plane and out-of-plane magnetic field on these states and discuss the implication for their spin- and valley- polarization. alternative_title: - Bulletin of the American Physical Society article_number: B51.00005 article_processing_charge: No author: - first_name: Hryhoriy full_name: Polshyn, Hryhoriy id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48 last_name: Polshyn orcid: 0000-0001-8223-8896 - first_name: Jihang full_name: Zhu, Jihang last_name: Zhu - first_name: Manish full_name: Kumar, Manish last_name: Kumar - first_name: Takashi full_name: Taniguchi, Takashi last_name: Taniguchi - first_name: Kenji full_name: Watanabe, Kenji last_name: Watanabe - first_name: Allan full_name: MacDonald, Allan last_name: MacDonald - first_name: Andrea full_name: Young, Andrea last_name: Young citation: ama: 'Polshyn H, Zhu J, Kumar M, et al. Correlated states and tunable topological bands in twisted monolayer-bilayer graphene heterostructures. In: APS March Meeting 2020. Vol 65. American Physical Society; 2020.' apa: 'Polshyn, H., Zhu, J., Kumar, M., Taniguchi, T., Watanabe, K., MacDonald, A., & Young, A. (2020). Correlated states and tunable topological bands in twisted monolayer-bilayer graphene heterostructures. In APS March Meeting 2020 (Vol. 65). Denver, CO, United States: American Physical Society.' chicago: Polshyn, Hryhoriy, Jihang Zhu, Manish Kumar, Takashi Taniguchi, Kenji Watanabe, Allan MacDonald, and Andrea Young. “Correlated States and Tunable Topological Bands in Twisted Monolayer-Bilayer Graphene Heterostructures.” In APS March Meeting 2020, Vol. 65. American Physical Society, 2020. ieee: H. Polshyn et al., “Correlated states and tunable topological bands in twisted monolayer-bilayer graphene heterostructures,” in APS March Meeting 2020, Denver, CO, United States, 2020, vol. 65, no. 1. ista: 'Polshyn H, Zhu J, Kumar M, Taniguchi T, Watanabe K, MacDonald A, Young A. 2020. Correlated states and tunable topological bands in twisted monolayer-bilayer graphene heterostructures. APS March Meeting 2020. APS: American Physical Society, Bulletin of the American Physical Society, vol. 65, B51.00005.' mla: Polshyn, Hryhoriy, et al. “Correlated States and Tunable Topological Bands in Twisted Monolayer-Bilayer Graphene Heterostructures.” APS March Meeting 2020, vol. 65, no. 1, B51.00005, American Physical Society, 2020. short: H. Polshyn, J. Zhu, M. Kumar, T. Taniguchi, K. Watanabe, A. MacDonald, A. Young, in:, APS March Meeting 2020, American Physical Society, 2020. conference: end_date: 2020-03-06 location: Denver, CO, United States name: 'APS: American Physical Society' start_date: 2020-03-02 date_created: 2022-01-28T10:09:19Z date_published: 2020-03-01T00:00:00Z date_updated: 2022-02-08T10:22:08Z day: '01' extern: '1' intvolume: ' 65' issue: '1' language: - iso: eng main_file_link: - open_access: '1' url: https://meetings.aps.org/Meeting/MAR20/Session/B51.5 month: '03' oa: 1 oa_version: Published Version publication: APS March Meeting 2020 publication_identifier: issn: - 0003-0503 publication_status: published publisher: American Physical Society quality_controlled: '1' status: public title: Correlated states and tunable topological bands in twisted monolayer-bilayer graphene heterostructures type: conference user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9 volume: 65 year: '2020' ... --- _id: '10701' abstract: - lang: eng text: Partially filled Landau levels host competing electronic orders. For example, electron solids may prevail close to integer filling of the Landau levels before giving way to fractional quantum Hall liquids at higher carrier density1,2. Here, we report the observation of an electron solid with non-collinear spin texture in monolayer graphene, consistent with solidification of skyrmions3—topological spin textures characterized by quantized electrical charge4,5. We probe the spin texture of the solids using a modified Corbino geometry that allows ferromagnetic magnons to be launched and detected6,7. We find that magnon transport is highly efficient when one Landau level is filled (ν=1), consistent with quantum Hall ferromagnetic spin polarization. However, even minimal doping immediately quenches the magnon signal while leaving the vanishing low-temperature charge conductivity unchanged. Our results can be understood by the formation of a solid of charged skyrmions near ν=1, whose non-collinear spin texture leads to rapid magnon decay. Data near fractional fillings show evidence of several fractional skyrmion solids, suggesting that graphene hosts a highly tunable landscape of coupled spin and charge orders. acknowledgement: We acknowledge discussions with B. Halperin, C. Huang, A. Macdonald and M. Zalatel. Experimental work at UCSB was supported by the Army Research Office under awards nos. MURI W911NF-16-1-0361 and W911NF-16-1-0482. K.W. and T.T. acknowledge support from the Elemental Strategy Initiative conducted by MEXT (Japan) and CREST (JPMJCR15F3), JST. A.F.Y. acknowledges the support of the David and Lucile Packard Foundation and and Alfred. P. Sloan Foundation. article_processing_charge: No article_type: original author: - first_name: Haoxin full_name: Zhou, Haoxin last_name: Zhou - first_name: Hryhoriy full_name: Polshyn, Hryhoriy id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48 last_name: Polshyn orcid: 0000-0001-8223-8896 - first_name: Takashi full_name: Taniguchi, Takashi last_name: Taniguchi - first_name: Kenji full_name: Watanabe, Kenji last_name: Watanabe - first_name: Andrea F. full_name: Young, Andrea F. last_name: Young citation: ama: Zhou H, Polshyn H, Taniguchi T, Watanabe K, Young AF. Skyrmion solids in monolayer graphene. Nature Physics. 2020;16(2):154-158. doi:10.1038/s41567-019-0729-8 apa: Zhou, H., Polshyn, H., Taniguchi, T., Watanabe, K., & Young, A. F. (2020). Skyrmion solids in monolayer graphene. Nature Physics. Springer Nature. https://doi.org/10.1038/s41567-019-0729-8 chicago: Zhou, Haoxin, Hryhoriy Polshyn, Takashi Taniguchi, Kenji Watanabe, and Andrea F. Young. “Skyrmion Solids in Monolayer Graphene.” Nature Physics. Springer Nature, 2020. https://doi.org/10.1038/s41567-019-0729-8. ieee: H. Zhou, H. Polshyn, T. Taniguchi, K. Watanabe, and A. F. Young, “Skyrmion solids in monolayer graphene,” Nature Physics, vol. 16, no. 2. Springer Nature, pp. 154–158, 2020. ista: Zhou H, Polshyn H, Taniguchi T, Watanabe K, Young AF. 2020. Skyrmion solids in monolayer graphene. Nature Physics. 16(2), 154–158. mla: Zhou, Haoxin, et al. “Skyrmion Solids in Monolayer Graphene.” Nature Physics, vol. 16, no. 2, Springer Nature, 2020, pp. 154–58, doi:10.1038/s41567-019-0729-8. short: H. Zhou, H. Polshyn, T. Taniguchi, K. Watanabe, A.F. Young, Nature Physics 16 (2020) 154–158. date_created: 2022-01-28T12:04:09Z date_published: 2020-02-01T00:00:00Z date_updated: 2022-01-31T07:10:07Z day: '01' doi: 10.1038/s41567-019-0729-8 extern: '1' external_id: arxiv: - '1904.11485' intvolume: ' 16' issue: '2' language: - iso: eng main_file_link: - open_access: '1' url: https://arxiv.org/abs/1904.11485 month: '02' oa: 1 oa_version: Preprint page: 154-158 publication: Nature Physics publication_identifier: eissn: - 1745-2481 issn: - 1745-2473 publication_status: published publisher: Springer Nature quality_controlled: '1' status: public title: Skyrmion solids in monolayer graphene type: journal_article user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9 volume: 16 year: '2020' ... --- _id: '11056' abstract: - lang: eng text: Aging of the circulatory system correlates with the pathogenesis of a large spectrum of diseases. However, it is largely unknown which factors drive the age-dependent or pathological decline of the vasculature and how vascular defects relate to tissue aging. The goal of the study is to design a multianalytical approach to identify how the cellular microenvironment (i.e., fibroblasts) and serum from healthy donors of different ages or Alzheimer disease (AD) patients can modulate the functionality of organ-specific vascular endothelial cells (VECs). Long-living human microvascular networks embedding VECs and fibroblasts from skin biopsies are generated. RNA-seq, secretome analyses, and microfluidic assays demonstrate that fibroblasts from young donors restore the functionality of aged endothelial cells, an effect also achieved by serum from young donors. New biomarkers of vascular aging are validated in human biopsies and it is shown that young serum induces angiopoietin-like-4, which can restore compromised vascular barriers. This strategy is then employed to characterize transcriptional/functional changes induced on the blood–brain barrier by AD serum, demonstrating the importance of PTP4A3 in the regulation of permeability. Features of vascular degeneration during aging and AD are recapitulated, and a tool to identify novel biomarkers that can be exploited to develop future therapeutics modulating vascular function is established. article_number: '2000044' article_processing_charge: No article_type: original author: - first_name: Simone full_name: Bersini, Simone last_name: Bersini - first_name: Rafael full_name: Arrojo e Drigo, Rafael last_name: Arrojo e Drigo - first_name: Ling full_name: Huang, Ling last_name: Huang - first_name: Maxim N. full_name: Shokhirev, Maxim N. last_name: Shokhirev - first_name: Martin W full_name: HETZER, Martin W id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed last_name: HETZER orcid: 0000-0002-2111-992X citation: ama: Bersini S, Arrojo e Drigo R, Huang L, Shokhirev MN, Hetzer M. Transcriptional and functional changes of the human microvasculature during physiological aging and Alzheimer disease. Advanced Biosystems. 2020;4(5). doi:10.1002/adbi.202000044 apa: Bersini, S., Arrojo e Drigo, R., Huang, L., Shokhirev, M. N., & Hetzer, M. (2020). Transcriptional and functional changes of the human microvasculature during physiological aging and Alzheimer disease. Advanced Biosystems. Wiley. https://doi.org/10.1002/adbi.202000044 chicago: Bersini, Simone, Rafael Arrojo e Drigo, Ling Huang, Maxim N. Shokhirev, and Martin Hetzer. “Transcriptional and Functional Changes of the Human Microvasculature during Physiological Aging and Alzheimer Disease.” Advanced Biosystems. Wiley, 2020. https://doi.org/10.1002/adbi.202000044. ieee: S. Bersini, R. Arrojo e Drigo, L. Huang, M. N. Shokhirev, and M. Hetzer, “Transcriptional and functional changes of the human microvasculature during physiological aging and Alzheimer disease,” Advanced Biosystems, vol. 4, no. 5. Wiley, 2020. ista: Bersini S, Arrojo e Drigo R, Huang L, Shokhirev MN, Hetzer M. 2020. Transcriptional and functional changes of the human microvasculature during physiological aging and Alzheimer disease. Advanced Biosystems. 4(5), 2000044. mla: Bersini, Simone, et al. “Transcriptional and Functional Changes of the Human Microvasculature during Physiological Aging and Alzheimer Disease.” Advanced Biosystems, vol. 4, no. 5, 2000044, Wiley, 2020, doi:10.1002/adbi.202000044. short: S. Bersini, R. Arrojo e Drigo, L. Huang, M.N. Shokhirev, M. Hetzer, Advanced Biosystems 4 (2020). date_created: 2022-04-07T07:43:57Z date_published: 2020-05-01T00:00:00Z date_updated: 2022-07-18T08:30:48Z day: '01' ddc: - '570' doi: 10.1002/adbi.202000044 extern: '1' external_id: pmid: - '32402127' file: - access_level: open_access checksum: 5584d9a1609812dc75c02ce1e35d2ec0 content_type: application/pdf creator: dernst date_created: 2022-04-08T07:06:05Z date_updated: 2022-04-08T07:06:05Z file_id: '11134' file_name: 2020_AdvancedBiosystems_Bersini.pdf file_size: 2490829 relation: main_file success: 1 file_date_updated: 2022-04-08T07:06:05Z has_accepted_license: '1' intvolume: ' 4' issue: '5' keyword: - General Biochemistry - Genetics and Molecular Biology - Biomedical Engineering - Biomaterials language: - iso: eng license: https://creativecommons.org/licenses/by-nc-nd/4.0/ month: '05' oa: 1 oa_version: Published Version pmid: 1 publication: Advanced Biosystems publication_identifier: issn: - 2366-7478 - 2366-7478 publication_status: published publisher: Wiley quality_controlled: '1' scopus_import: '1' status: public title: Transcriptional and functional changes of the human microvasculature during physiological aging and Alzheimer disease tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: journal_article user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd volume: 4 year: '2020' ... --- _id: '11055' abstract: - lang: eng text: Vascular dysfunctions are a common feature of multiple age-related diseases. However, modeling healthy and pathological aging of the human vasculature represents an unresolved experimental challenge. Here, we generated induced vascular endothelial cells (iVECs) and smooth muscle cells (iSMCs) by direct reprogramming of healthy human fibroblasts from donors of different ages and Hutchinson-Gilford Progeria Syndrome (HGPS) patients. iVECs induced from old donors revealed upregulation of GSTM1 and PALD1, genes linked to oxidative stress, inflammation and endothelial junction stability, as vascular aging markers. A functional assay performed on PALD1 KD VECs demonstrated a recovery in vascular permeability. We found that iSMCs from HGPS donors overexpressed bone morphogenetic protein (BMP)−4, which plays a key role in both vascular calcification and endothelial barrier damage observed in HGPS. Strikingly, BMP4 concentrations are higher in serum from HGPS vs. age-matched mice. Furthermore, targeting BMP4 with blocking antibody recovered the functionality of the vascular barrier in vitro, hence representing a potential future therapeutic strategy to limit cardiovascular dysfunction in HGPS. These results show that iVECs and iSMCs retain disease-related signatures, allowing modeling of vascular aging and HGPS in vitro. article_number: e54383 article_processing_charge: No article_type: original author: - first_name: Simone full_name: Bersini, Simone last_name: Bersini - first_name: Roberta full_name: Schulte, Roberta last_name: Schulte - first_name: Ling full_name: Huang, Ling last_name: Huang - first_name: Hannah full_name: Tsai, Hannah last_name: Tsai - first_name: Martin W full_name: HETZER, Martin W id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed last_name: HETZER orcid: 0000-0002-2111-992X citation: ama: Bersini S, Schulte R, Huang L, Tsai H, Hetzer M. Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome. eLife. 2020;9. doi:10.7554/elife.54383 apa: Bersini, S., Schulte, R., Huang, L., Tsai, H., & Hetzer, M. (2020). Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome. ELife. eLife Sciences Publications. https://doi.org/10.7554/elife.54383 chicago: Bersini, Simone, Roberta Schulte, Ling Huang, Hannah Tsai, and Martin Hetzer. “Direct Reprogramming of Human Smooth Muscle and Vascular Endothelial Cells Reveals Defects Associated with Aging and Hutchinson-Gilford Progeria Syndrome.” ELife. eLife Sciences Publications, 2020. https://doi.org/10.7554/elife.54383. ieee: S. Bersini, R. Schulte, L. Huang, H. Tsai, and M. Hetzer, “Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome,” eLife, vol. 9. eLife Sciences Publications, 2020. ista: Bersini S, Schulte R, Huang L, Tsai H, Hetzer M. 2020. Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome. eLife. 9, e54383. mla: Bersini, Simone, et al. “Direct Reprogramming of Human Smooth Muscle and Vascular Endothelial Cells Reveals Defects Associated with Aging and Hutchinson-Gilford Progeria Syndrome.” ELife, vol. 9, e54383, eLife Sciences Publications, 2020, doi:10.7554/elife.54383. short: S. Bersini, R. Schulte, L. Huang, H. Tsai, M. Hetzer, ELife 9 (2020). date_created: 2022-04-07T07:43:48Z date_published: 2020-09-08T00:00:00Z date_updated: 2022-07-18T08:30:37Z day: '08' ddc: - '570' doi: 10.7554/elife.54383 extern: '1' external_id: pmid: - '32896271' file: - access_level: open_access checksum: f8b3821349a194050be02570d8fe7d4b content_type: application/pdf creator: dernst date_created: 2022-04-08T06:53:10Z date_updated: 2022-04-08T06:53:10Z file_id: '11132' file_name: 2020_eLife_Bersini.pdf file_size: 4399825 relation: main_file success: 1 file_date_updated: 2022-04-08T06:53:10Z has_accepted_license: '1' intvolume: ' 9' keyword: - General Immunology and Microbiology - General Biochemistry - Genetics and Molecular Biology - General Medicine - General Neuroscience language: - iso: eng license: https://creativecommons.org/licenses/by/4.0/ month: '09' oa: 1 oa_version: Published Version pmid: 1 publication: eLife publication_identifier: issn: - 2050-084X publication_status: published publisher: eLife Sciences Publications quality_controlled: '1' scopus_import: '1' status: public title: Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd volume: 9 year: '2020' ... --- _id: '11054' abstract: - lang: eng text: In recent years, the nuclear pore complex (NPC) has emerged as a key player in genome regulation and cellular homeostasis. New discoveries have revealed that the NPC has multiple cellular functions besides mediating the molecular exchange between the nucleus and the cytoplasm. In this review, we discuss non-transport aspects of the NPC focusing on the NPC-genome interaction, the extreme longevity of the NPC proteins, and NPC dysfunction in age-related diseases. The examples summarized herein demonstrate that the NPC, which first evolved to enable the biochemical communication between the nucleus and the cytoplasm, now doubles as the gatekeeper of cellular identity and aging. article_processing_charge: No article_type: review author: - first_name: Ukrae H. full_name: Cho, Ukrae H. last_name: Cho - first_name: Martin W full_name: HETZER, Martin W id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed last_name: HETZER orcid: 0000-0002-2111-992X citation: ama: 'Cho UH, Hetzer M. Nuclear periphery takes center stage: The role of nuclear pore complexes in cell identity and aging. Neuron. 2020;106(6):899-911. doi:10.1016/j.neuron.2020.05.031' apa: 'Cho, U. H., & Hetzer, M. (2020). Nuclear periphery takes center stage: The role of nuclear pore complexes in cell identity and aging. Neuron. Elsevier. https://doi.org/10.1016/j.neuron.2020.05.031' chicago: 'Cho, Ukrae H., and Martin Hetzer. “Nuclear Periphery Takes Center Stage: The Role of Nuclear Pore Complexes in Cell Identity and Aging.” Neuron. Elsevier, 2020. https://doi.org/10.1016/j.neuron.2020.05.031.' ieee: 'U. H. Cho and M. Hetzer, “Nuclear periphery takes center stage: The role of nuclear pore complexes in cell identity and aging,” Neuron, vol. 106, no. 6. Elsevier, pp. 899–911, 2020.' ista: 'Cho UH, Hetzer M. 2020. Nuclear periphery takes center stage: The role of nuclear pore complexes in cell identity and aging. Neuron. 106(6), 899–911.' mla: 'Cho, Ukrae H., and Martin Hetzer. “Nuclear Periphery Takes Center Stage: The Role of Nuclear Pore Complexes in Cell Identity and Aging.” Neuron, vol. 106, no. 6, Elsevier, 2020, pp. 899–911, doi:10.1016/j.neuron.2020.05.031.' short: U.H. Cho, M. Hetzer, Neuron 106 (2020) 899–911. date_created: 2022-04-07T07:43:36Z date_published: 2020-06-17T00:00:00Z date_updated: 2022-07-18T08:29:35Z day: '17' doi: 10.1016/j.neuron.2020.05.031 extern: '1' external_id: pmid: - '32553207' intvolume: ' 106' issue: '6' keyword: - General Neuroscience language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1016/j.neuron.2020.05.031 month: '06' oa: 1 oa_version: Published Version page: 899-911 pmid: 1 publication: Neuron publication_identifier: issn: - 0896-6273 publication_status: published publisher: Elsevier quality_controlled: '1' scopus_import: '1' status: public title: 'Nuclear periphery takes center stage: The role of nuclear pore complexes in cell identity and aging' type: journal_article user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd volume: 106 year: '2020' ... --- _id: '11057' abstract: - lang: eng text: During mitosis, transcription of genomic DNA is dramatically reduced, before it is reactivated during nuclear reformation in anaphase/telophase. Many aspects of the underlying principles that mediate transcriptional memory and reactivation in the daughter cells remain unclear. Here, we used ChIP-seq on synchronized cells at different stages after mitosis to generate genome-wide maps of histone modifications. Combined with EU-RNA-seq and Hi-C analyses, we found that during prometaphase, promoters, enhancers, and insulators retain H3K4me3 and H3K4me1, while losing H3K27ac. Enhancers globally retaining mitotic H3K4me1 or locally retaining mitotic H3K27ac are associated with cell type-specific genes and their transcription factors for rapid transcriptional activation. As cells exit mitosis, promoters regain H3K27ac, which correlates with transcriptional reactivation. Insulators also gain H3K27ac and CCCTC-binding factor (CTCF) in anaphase/telophase. This increase of H3K27ac in anaphase/telophase is required for posttranscriptional activation and may play a role in the establishment of topologically associating domains (TADs). Together, our results suggest that the genome is reorganized in a sequential order, in which histone methylations occur first in prometaphase, histone acetylation, and CTCF in anaphase/telophase, transcription in cytokinesis, and long-range chromatin interactions in early G1. We thus provide insights into the histone modification landscape that allows faithful reestablishment of the transcriptional program and TADs during cell division. article_processing_charge: No article_type: original author: - first_name: Hyeseon full_name: Kang, Hyeseon last_name: Kang - first_name: Maxim N. full_name: Shokhirev, Maxim N. last_name: Shokhirev - first_name: Zhichao full_name: Xu, Zhichao last_name: Xu - first_name: Sahaana full_name: Chandran, Sahaana last_name: Chandran - first_name: Jesse R. full_name: Dixon, Jesse R. last_name: Dixon - first_name: Martin W full_name: HETZER, Martin W id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed last_name: HETZER orcid: 0000-0002-2111-992X citation: ama: Kang H, Shokhirev MN, Xu Z, Chandran S, Dixon JR, Hetzer M. Dynamic regulation of histone modifications and long-range chromosomal interactions during postmitotic transcriptional reactivation. Genes & Development. 2020;34(13-14):913-930. doi:10.1101/gad.335794.119 apa: Kang, H., Shokhirev, M. N., Xu, Z., Chandran, S., Dixon, J. R., & Hetzer, M. (2020). Dynamic regulation of histone modifications and long-range chromosomal interactions during postmitotic transcriptional reactivation. Genes & Development. Cold Spring Harbor Laboratory Press. https://doi.org/10.1101/gad.335794.119 chicago: Kang, Hyeseon, Maxim N. Shokhirev, Zhichao Xu, Sahaana Chandran, Jesse R. Dixon, and Martin Hetzer. “Dynamic Regulation of Histone Modifications and Long-Range Chromosomal Interactions during Postmitotic Transcriptional Reactivation.” Genes & Development. Cold Spring Harbor Laboratory Press, 2020. https://doi.org/10.1101/gad.335794.119. ieee: H. Kang, M. N. Shokhirev, Z. Xu, S. Chandran, J. R. Dixon, and M. Hetzer, “Dynamic regulation of histone modifications and long-range chromosomal interactions during postmitotic transcriptional reactivation,” Genes & Development, vol. 34, no. 13–14. Cold Spring Harbor Laboratory Press, pp. 913–930, 2020. ista: Kang H, Shokhirev MN, Xu Z, Chandran S, Dixon JR, Hetzer M. 2020. Dynamic regulation of histone modifications and long-range chromosomal interactions during postmitotic transcriptional reactivation. Genes & Development. 34(13–14), 913–930. mla: Kang, Hyeseon, et al. “Dynamic Regulation of Histone Modifications and Long-Range Chromosomal Interactions during Postmitotic Transcriptional Reactivation.” Genes & Development, vol. 34, no. 13–14, Cold Spring Harbor Laboratory Press, 2020, pp. 913–30, doi:10.1101/gad.335794.119. short: H. Kang, M.N. Shokhirev, Z. Xu, S. Chandran, J.R. Dixon, M. Hetzer, Genes & Development 34 (2020) 913–930. date_created: 2022-04-07T07:44:09Z date_published: 2020-04-28T00:00:00Z date_updated: 2022-07-18T08:31:08Z day: '28' ddc: - '570' doi: 10.1101/gad.335794.119 extern: '1' external_id: pmid: - '32499403' file: - access_level: open_access checksum: 84e92d40e67936c739628315c238daf9 content_type: application/pdf creator: dernst date_created: 2022-04-08T07:12:33Z date_updated: 2022-04-08T07:12:33Z file_id: '11136' file_name: 2020_GenesDevelopment_Kang.pdf file_size: 4406772 relation: main_file success: 1 file_date_updated: 2022-04-08T07:12:33Z has_accepted_license: '1' intvolume: ' 34' issue: 13-14 keyword: - Developmental Biology - Genetics language: - iso: eng month: '04' oa: 1 oa_version: Published Version page: 913-930 pmid: 1 publication: Genes & Development publication_identifier: issn: - 0890-9369 - 1549-5477 publication_status: published publisher: Cold Spring Harbor Laboratory Press quality_controlled: '1' scopus_import: '1' status: public title: Dynamic regulation of histone modifications and long-range chromosomal interactions during postmitotic transcriptional reactivation tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd volume: 34 year: '2020' ... --- _id: '11058' abstract: - lang: eng text: Nucleoporin 93 (Nup93) expression inversely correlates with the survival of triple-negative breast cancer patients. However, our knowledge of Nup93 function in breast cancer besides its role as structural component of the nuclear pore complex is not understood. Combination of functional assays and genetic analyses suggested that chromatin interaction of Nup93 partially modulates the expression of genes associated with actin cytoskeleton remodeling and epithelial to mesenchymal transition, resulting in impaired invasion of triple-negative, claudin-low breast cancer cells. Nup93 depletion induced stress fiber formation associated with reduced cell migration/proliferation and impaired expression of mesenchymal-like genes. Silencing LIMCH1, a gene responsible for actin cytoskeleton remodeling and up-regulated upon Nup93 depletion, partially restored the invasive phenotype of cancer cells. Loss of Nup93 led to significant defects in tumor establishment/propagation in vivo, whereas patient samples revealed that high Nup93 and low LIMCH1 expression correlate with late tumor stage. Our approach identified Nup93 as contributor of triple-negative, claudin-low breast cancer cell invasion and paves the way to study the role of nuclear envelope proteins during breast cancer tumorigenesis. article_number: e201900623 article_processing_charge: No article_type: original author: - first_name: Simone full_name: Bersini, Simone last_name: Bersini - first_name: Nikki K full_name: Lytle, Nikki K last_name: Lytle - first_name: Roberta full_name: Schulte, Roberta last_name: Schulte - first_name: Ling full_name: Huang, Ling last_name: Huang - first_name: Geoffrey M full_name: Wahl, Geoffrey M last_name: Wahl - first_name: Martin W full_name: HETZER, Martin W id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed last_name: HETZER orcid: 0000-0002-2111-992X citation: ama: Bersini S, Lytle NK, Schulte R, Huang L, Wahl GM, Hetzer M. Nup93 regulates breast tumor growth by modulating cell proliferation and actin cytoskeleton remodeling. Life Science Alliance. 2020;3(1). doi:10.26508/lsa.201900623 apa: Bersini, S., Lytle, N. K., Schulte, R., Huang, L., Wahl, G. M., & Hetzer, M. (2020). Nup93 regulates breast tumor growth by modulating cell proliferation and actin cytoskeleton remodeling. Life Science Alliance. Life Science Alliance. https://doi.org/10.26508/lsa.201900623 chicago: Bersini, Simone, Nikki K Lytle, Roberta Schulte, Ling Huang, Geoffrey M Wahl, and Martin Hetzer. “Nup93 Regulates Breast Tumor Growth by Modulating Cell Proliferation and Actin Cytoskeleton Remodeling.” Life Science Alliance. Life Science Alliance, 2020. https://doi.org/10.26508/lsa.201900623. ieee: S. Bersini, N. K. Lytle, R. Schulte, L. Huang, G. M. Wahl, and M. Hetzer, “Nup93 regulates breast tumor growth by modulating cell proliferation and actin cytoskeleton remodeling,” Life Science Alliance, vol. 3, no. 1. Life Science Alliance, 2020. ista: Bersini S, Lytle NK, Schulte R, Huang L, Wahl GM, Hetzer M. 2020. Nup93 regulates breast tumor growth by modulating cell proliferation and actin cytoskeleton remodeling. Life Science Alliance. 3(1), e201900623. mla: Bersini, Simone, et al. “Nup93 Regulates Breast Tumor Growth by Modulating Cell Proliferation and Actin Cytoskeleton Remodeling.” Life Science Alliance, vol. 3, no. 1, e201900623, Life Science Alliance, 2020, doi:10.26508/lsa.201900623. short: S. Bersini, N.K. Lytle, R. Schulte, L. Huang, G.M. Wahl, M. Hetzer, Life Science Alliance 3 (2020). date_created: 2022-04-07T07:44:18Z date_published: 2020-01-01T00:00:00Z date_updated: 2022-07-18T08:31:20Z day: '01' ddc: - '570' doi: 10.26508/lsa.201900623 extern: '1' external_id: pmid: - '31959624' file: - access_level: open_access checksum: 3bf33e7e93bef7823287807206b69b38 content_type: application/pdf creator: dernst date_created: 2022-04-08T07:33:01Z date_updated: 2022-04-08T07:33:01Z file_id: '11137' file_name: 2020_LifeScienceAlliance_Bersini.pdf file_size: 2653960 relation: main_file success: 1 file_date_updated: 2022-04-08T07:33:01Z has_accepted_license: '1' intvolume: ' 3' issue: '1' keyword: - Health - Toxicology and Mutagenesis - Plant Science - Biochemistry - Genetics and Molecular Biology (miscellaneous) - Ecology language: - iso: eng month: '01' oa: 1 oa_version: Published Version pmid: 1 publication: Life Science Alliance publication_identifier: issn: - 2575-1077 publication_status: published publisher: Life Science Alliance quality_controlled: '1' scopus_import: '1' status: public title: Nup93 regulates breast tumor growth by modulating cell proliferation and actin cytoskeleton remodeling tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd volume: 3 year: '2020' ... --- _id: '11503' abstract: - lang: eng text: "Context. The Lyα emitter (LAE) fraction, XLAE, is a potentially powerful probe of the evolution of the intergalactic neutral hydrogen gas fraction. However, uncertainties in the measurement of XLAE are still under debate.\r\nAims. Thanks to deep data obtained with the integral field spectrograph Multi Unit Spectroscopic Explorer (MUSE), we can measure the evolution of the LAE fraction homogeneously over a wide redshift range of z ≈ 3–6 for UV-faint galaxies (down to UV magnitudes of M1500 ≈ −17.75). This is a significantly fainter range than in former studies (M1500 ≤ −18.75) and it allows us to probe the bulk of the population of high-redshift star-forming galaxies.\r\nMethods. We constructed a UV-complete photometric-redshift sample following UV luminosity functions and measured the Lyα emission with MUSE using the latest (second) data release from the MUSE Hubble Ultra Deep Field Survey.\r\nResults. We derived the redshift evolution of XLAE for M1500 ∈ [ − 21.75; −17.75] for the first time with a equivalent width range EW(Lyα) ≥ 65 Å and found low values of XLAE ≲ 30% at z ≲ 6. The best-fit linear relation is XLAE = 0.07+0.06−0.03z − 0.22+0.12−0.24. For M1500 ∈ [ − 20.25; −18.75] and EW(Lyα) ≥ 25 Å, our XLAE values are consistent with those in the literature within 1σ at z ≲ 5, but our median values are systematically lower than reported values over the whole redshift range. In addition, we do not find a significant dependence of XLAE on M1500 for EW(Lyα) ≥ 50 Å at z ≈ 3–4, in contrast with previous work. The differences in XLAE mainly arise from selection biases for Lyman Break Galaxies (LBGs) in the literature: UV-faint LBGs are more easily selected if they have strong Lyα emission, hence XLAE is biased towards higher values when those samples are used.\r\nConclusions. Our results suggest either a lower increase of XLAE towards z ≈ 6 than previously suggested, or even a turnover of XLAE at z ≈ 5.5, which may be the signature of a late or patchy reionization process. We compared our results with predictions from a cosmological galaxy evolution model. We find that a model with a bursty star formation (SF) can reproduce our observed LAE fractions much better than models where SF is a smooth function of time." acknowledgement: We thank the anonymous referee for constructive comments and suggestions. We would like to express our gratitude to Stephane De Barros and Pablo Arrabal Haro for kindly providing their data plotted in Figs. 1, 2, and 8. We are grateful to Kazuhiro Shimasaku, Masami Ouchi, Rieko Momose, Daniel Schaerer, Hidenobu Yajima, Taku Okamura, Makoto Ando, and Hinako Goto for giving insightful comments and suggestions. This work is based on observations taken by VLT, which is operated by European Southern Observatory. This research made use of Astropy (http://www.astropy.org), which is a community-developed core Python package for Astronomy (Astropy Collaboration 2013, 2018), MARZ, MPDAF, and matplotlib (Hunter 2007). H.K. acknowledges support from Japan Society for the Promotion of Science (JSPS) through the JSPS Research Fellowship for Young Scientists and Overseas Challenge Program for Young Researchers. AV acknowledges support from the ERC starting grant 757258-TRIPLE and the SNF Professorship 176808-TRIPLE. This work was supported by the project FOGHAR (Agence Nationale de la Recherche, ANR-13-BS05-0010-02). JB acknowledges support from the ORAGE project from the Agence Nationale de la Recherche under grant ANR-14-CE33-0016-03. JR acknowledges support from the ERC starting grant 336736-CALENDS. T. H. acknowledges supports by the Grant-inAid for Scientic Research 19J01620. article_number: A12 article_processing_charge: No article_type: original author: - first_name: Haruka full_name: Kusakabe, Haruka last_name: Kusakabe - first_name: Jérémy full_name: Blaizot, Jérémy last_name: Blaizot - first_name: Thibault full_name: Garel, Thibault last_name: Garel - first_name: Anne full_name: Verhamme, Anne last_name: Verhamme - first_name: Roland full_name: Bacon, Roland last_name: Bacon - first_name: Johan full_name: Richard, Johan last_name: Richard - first_name: Takuya full_name: Hashimoto, Takuya last_name: Hashimoto - first_name: Hanae full_name: Inami, Hanae last_name: Inami - first_name: Simon full_name: Conseil, Simon last_name: Conseil - first_name: Bruno full_name: Guiderdoni, Bruno last_name: Guiderdoni - first_name: Alyssa B. full_name: Drake, Alyssa B. last_name: Drake - first_name: Edmund full_name: Christian Herenz, Edmund last_name: Christian Herenz - first_name: Joop full_name: Schaye, Joop last_name: Schaye - first_name: Pascal full_name: Oesch, Pascal last_name: Oesch - first_name: Jorryt J full_name: Matthee, Jorryt J id: 7439a258-f3c0-11ec-9501-9df22fe06720 last_name: Matthee orcid: 0000-0003-2871-127X - first_name: Raffaella full_name: Anna Marino, Raffaella last_name: Anna Marino - first_name: Kasper full_name: Borello Schmidt, Kasper last_name: Borello Schmidt - first_name: Roser full_name: Pelló, Roser last_name: Pelló - first_name: Michael full_name: Maseda, Michael last_name: Maseda - first_name: Floriane full_name: Leclercq, Floriane last_name: Leclercq - first_name: Josephine full_name: Kerutt, Josephine last_name: Kerutt - first_name: Guillaume full_name: Mahler, Guillaume last_name: Mahler citation: ama: 'Kusakabe H, Blaizot J, Garel T, et al. The MUSE Hubble Ultra Deep Field Survey: XIV. Evolution of the Lyα emitter fraction from z = 3 to z = 6. Astronomy & Astrophysics. 2020;638. doi:10.1051/0004-6361/201937340' apa: 'Kusakabe, H., Blaizot, J., Garel, T., Verhamme, A., Bacon, R., Richard, J., … Mahler, G. (2020). The MUSE Hubble Ultra Deep Field Survey: XIV. Evolution of the Lyα emitter fraction from z = 3 to z = 6. Astronomy & Astrophysics. EDP Sciences. https://doi.org/10.1051/0004-6361/201937340' chicago: 'Kusakabe, Haruka, Jérémy Blaizot, Thibault Garel, Anne Verhamme, Roland Bacon, Johan Richard, Takuya Hashimoto, et al. “The MUSE Hubble Ultra Deep Field Survey: XIV. Evolution of the Lyα Emitter Fraction from z = 3 to z = 6.” Astronomy & Astrophysics. EDP Sciences, 2020. https://doi.org/10.1051/0004-6361/201937340.' ieee: 'H. Kusakabe et al., “The MUSE Hubble Ultra Deep Field Survey: XIV. Evolution of the Lyα emitter fraction from z = 3 to z = 6,” Astronomy & Astrophysics, vol. 638. EDP Sciences, 2020.' ista: 'Kusakabe H, Blaizot J, Garel T, Verhamme A, Bacon R, Richard J, Hashimoto T, Inami H, Conseil S, Guiderdoni B, Drake AB, Christian Herenz E, Schaye J, Oesch P, Matthee JJ, Anna Marino R, Borello Schmidt K, Pelló R, Maseda M, Leclercq F, Kerutt J, Mahler G. 2020. The MUSE Hubble Ultra Deep Field Survey: XIV. Evolution of the Lyα emitter fraction from z = 3 to z = 6. Astronomy & Astrophysics. 638, A12.' mla: 'Kusakabe, Haruka, et al. “The MUSE Hubble Ultra Deep Field Survey: XIV. Evolution of the Lyα Emitter Fraction from z = 3 to z = 6.” Astronomy & Astrophysics, vol. 638, A12, EDP Sciences, 2020, doi:10.1051/0004-6361/201937340.' short: H. Kusakabe, J. Blaizot, T. Garel, A. Verhamme, R. Bacon, J. Richard, T. Hashimoto, H. Inami, S. Conseil, B. Guiderdoni, A.B. Drake, E. Christian Herenz, J. Schaye, P. Oesch, J.J. Matthee, R. Anna Marino, K. Borello Schmidt, R. Pelló, M. Maseda, F. Leclercq, J. Kerutt, G. Mahler, Astronomy & Astrophysics 638 (2020). date_created: 2022-07-06T09:50:48Z date_published: 2020-06-03T00:00:00Z date_updated: 2022-07-19T09:35:20Z day: '03' doi: 10.1051/0004-6361/201937340 extern: '1' external_id: arxiv: - '2003.12083' intvolume: ' 638' keyword: - Space and Planetary Science - Astronomy and Astrophysics - 'dark ages / reionization / first stars / early Universe / cosmology: observations / galaxies: evolution / galaxies: high-redshift / intergalactic medium' language: - iso: eng main_file_link: - open_access: '1' url: https://arxiv.org/abs/2003.12083 month: '06' oa: 1 oa_version: Published Version publication: Astronomy & Astrophysics publication_identifier: eissn: - 1432-0746 issn: - 0004-6361 publication_status: published publisher: EDP Sciences quality_controlled: '1' scopus_import: '1' status: public title: 'The MUSE Hubble Ultra Deep Field Survey: XIV. Evolution of the Lyα emitter fraction from z = 3 to z = 6' type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 638 year: '2020' ...