---
_id: '9121'
abstract:
- lang: eng
text: "We show that the energy gap for the BCS gap equation is\r\nΞ=μ(8e−2+o(1))exp(π2μ−−√a)\r\nin
the low density limit μ→0. Together with the similar result for the critical temperature
by Hainzl and Seiringer (Lett Math Phys 84: 99–107, 2008), this shows that, in
the low density limit, the ratio of the energy gap and critical temperature is
a universal constant independent of the interaction potential V. The results hold
for a class of potentials with negative scattering length a and no bound states."
acknowledgement: "Most of this work was done as part of the author’s master’s thesis.
The author would like to thank Jan Philip Solovej for his supervision of this process.\r\nOpen
Access funding provided by Institute of Science and Technology (IST Austria)"
article_number: '20'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Asbjørn Bækgaard
full_name: Lauritsen, Asbjørn Bækgaard
id: e1a2682f-dc8d-11ea-abe3-81da9ac728f1
last_name: Lauritsen
orcid: 0000-0003-4476-2288
citation:
ama: Lauritsen AB. The BCS energy gap at low density. Letters in Mathematical
Physics. 2021;111. doi:10.1007/s11005-021-01358-5
apa: Lauritsen, A. B. (2021). The BCS energy gap at low density. Letters in Mathematical
Physics. Springer Nature. https://doi.org/10.1007/s11005-021-01358-5
chicago: Lauritsen, Asbjørn Bækgaard. “The BCS Energy Gap at Low Density.” Letters
in Mathematical Physics. Springer Nature, 2021. https://doi.org/10.1007/s11005-021-01358-5.
ieee: A. B. Lauritsen, “The BCS energy gap at low density,” Letters in Mathematical
Physics, vol. 111. Springer Nature, 2021.
ista: Lauritsen AB. 2021. The BCS energy gap at low density. Letters in Mathematical
Physics. 111, 20.
mla: Lauritsen, Asbjørn Bækgaard. “The BCS Energy Gap at Low Density.” Letters
in Mathematical Physics, vol. 111, 20, Springer Nature, 2021, doi:10.1007/s11005-021-01358-5.
short: A.B. Lauritsen, Letters in Mathematical Physics 111 (2021).
date_created: 2021-02-15T09:27:14Z
date_published: 2021-02-12T00:00:00Z
date_updated: 2023-09-05T15:17:16Z
day: '12'
ddc:
- '510'
department:
- _id: GradSch
doi: 10.1007/s11005-021-01358-5
external_id:
isi:
- '000617531900001'
file:
- access_level: open_access
checksum: eaf1b3ff5026f120f0929a5c417dc842
content_type: application/pdf
creator: dernst
date_created: 2021-02-15T09:31:07Z
date_updated: 2021-02-15T09:31:07Z
file_id: '9122'
file_name: 2021_LettersMathPhysics_Lauritsen.pdf
file_size: 329332
relation: main_file
success: 1
file_date_updated: 2021-02-15T09:31:07Z
has_accepted_license: '1'
intvolume: ' 111'
isi: 1
keyword:
- Mathematical Physics
- Statistical and Nonlinear Physics
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
name: IST Austria Open Access Fund
publication: Letters in Mathematical Physics
publication_identifier:
eissn:
- 1573-0530
issn:
- 0377-9017
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: The BCS energy gap at low density
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 111
year: '2021'
...
---
_id: '9234'
abstract:
- lang: eng
text: In this paper, we present two new inertial projection-type methods for solving
multivalued variational inequality problems in finite-dimensional spaces. We establish
the convergence of the sequence generated by these methods when the multivalued
mapping associated with the problem is only required to be locally bounded without
any monotonicity assumption. Furthermore, the inertial techniques that we employ
in this paper are quite different from the ones used in most papers. Moreover,
based on the weaker assumptions on the inertial factor in our methods, we derive
several special cases of our methods. Finally, we present some experimental results
to illustrate the profits that we gain by introducing the inertial extrapolation
steps.
acknowledgement: 'The authors sincerely thank the Editor-in-Chief and anonymous referees
for their careful reading, constructive comments and fruitful suggestions that help
improve the manuscript. The research of the first author is supported by the National
Research Foundation (NRF) South Africa (S& F-DSI/NRF Free Standing Postdoctoral
Fellowship; Grant Number: 120784). The first author also acknowledges the financial
support from DSI/NRF, South Africa Center of Excellence in Mathematical and Statistical
Sciences (CoE-MaSS) Postdoctoral Fellowship. The second author has received funding
from the European Research Council (ERC) under the European Union’s Seventh Framework
Program (FP7 - 2007-2013) (Grant agreement No. 616160). Open Access funding provided
by Institute of Science and Technology (IST Austria).'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Chinedu
full_name: Izuchukwu, Chinedu
last_name: Izuchukwu
- first_name: Yekini
full_name: Shehu, Yekini
id: 3FC7CB58-F248-11E8-B48F-1D18A9856A87
last_name: Shehu
orcid: 0000-0001-9224-7139
citation:
ama: Izuchukwu C, Shehu Y. New inertial projection methods for solving multivalued
variational inequality problems beyond monotonicity. Networks and Spatial Economics.
2021;21(2):291-323. doi:10.1007/s11067-021-09517-w
apa: Izuchukwu, C., & Shehu, Y. (2021). New inertial projection methods for
solving multivalued variational inequality problems beyond monotonicity. Networks
and Spatial Economics. Springer Nature. https://doi.org/10.1007/s11067-021-09517-w
chicago: Izuchukwu, Chinedu, and Yekini Shehu. “New Inertial Projection Methods
for Solving Multivalued Variational Inequality Problems beyond Monotonicity.”
Networks and Spatial Economics. Springer Nature, 2021. https://doi.org/10.1007/s11067-021-09517-w.
ieee: C. Izuchukwu and Y. Shehu, “New inertial projection methods for solving multivalued
variational inequality problems beyond monotonicity,” Networks and Spatial
Economics, vol. 21, no. 2. Springer Nature, pp. 291–323, 2021.
ista: Izuchukwu C, Shehu Y. 2021. New inertial projection methods for solving multivalued
variational inequality problems beyond monotonicity. Networks and Spatial Economics.
21(2), 291–323.
mla: Izuchukwu, Chinedu, and Yekini Shehu. “New Inertial Projection Methods for
Solving Multivalued Variational Inequality Problems beyond Monotonicity.” Networks
and Spatial Economics, vol. 21, no. 2, Springer Nature, 2021, pp. 291–323,
doi:10.1007/s11067-021-09517-w.
short: C. Izuchukwu, Y. Shehu, Networks and Spatial Economics 21 (2021) 291–323.
date_created: 2021-03-10T12:18:47Z
date_published: 2021-06-01T00:00:00Z
date_updated: 2023-09-05T15:32:32Z
day: '01'
ddc:
- '510'
department:
- _id: VlKo
doi: 10.1007/s11067-021-09517-w
ec_funded: 1
external_id:
isi:
- '000625002100001'
file:
- access_level: open_access
checksum: 22b4253a2e5da843622a2df713784b4c
content_type: application/pdf
creator: kschuh
date_created: 2021-08-11T12:44:16Z
date_updated: 2021-08-11T12:44:16Z
file_id: '9884'
file_name: 2021_NetworksSpatialEconomics_Shehu.pdf
file_size: 834964
relation: main_file
success: 1
file_date_updated: 2021-08-11T12:44:16Z
has_accepted_license: '1'
intvolume: ' 21'
isi: 1
issue: '2'
keyword:
- Computer Networks and Communications
- Software
- Artificial Intelligence
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 291-323
project:
- _id: 25FBA906-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '616160'
name: 'Discrete Optimization in Computer Vision: Theory and Practice'
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
name: IST Austria Open Access Fund
publication: Networks and Spatial Economics
publication_identifier:
eissn:
- 1572-9427
issn:
- 1566-113X
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: New inertial projection methods for solving multivalued variational inequality
problems beyond monotonicity
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 21
year: '2021'
...
---
_id: '9111'
abstract:
- lang: eng
text: 'We study the probabilistic convergence between the mapper graph and the Reeb
graph of a topological space X equipped with a continuous function f:X→R. We first
give a categorification of the mapper graph and the Reeb graph by interpreting
them in terms of cosheaves and stratified covers of the real line R. We then introduce
a variant of the classic mapper graph of Singh et al. (in: Eurographics symposium
on point-based graphics, 2007), referred to as the enhanced mapper graph, and
demonstrate that such a construction approximates the Reeb graph of (X,f) when
it is applied to points randomly sampled from a probability density function concentrated
on (X,f). Our techniques are based on the interleaving distance of constructible
cosheaves and topological estimation via kernel density estimates. Following Munch
and Wang (In: 32nd international symposium on computational geometry, volume 51
of Leibniz international proceedings in informatics (LIPIcs), Dagstuhl, Germany,
pp 53:1–53:16, 2016), we first show that the mapper graph of (X,f), a constructible
R-space (with a fixed open cover), approximates the Reeb graph of the same space.
We then construct an isomorphism between the mapper of (X,f) to the mapper of
a super-level set of a probability density function concentrated on (X,f). Finally,
building on the approach of Bobrowski et al. (Bernoulli 23(1):288–328, 2017b),
we show that, with high probability, we can recover the mapper of the super-level
set given a sufficiently large sample. Our work is the first to consider the mapper
construction using the theory of cosheaves in a probabilistic setting. It is part
of an ongoing effort to combine sheaf theory, probability, and statistics, to
support topological data analysis with random data.'
acknowledgement: "AB was supported in part by the European Union’s Horizon 2020 research
and innovation\r\nprogramme under the Marie Sklodowska-Curie GrantAgreement No.
754411 and NSF IIS-1513616. OB was supported in part by the Israel Science Foundation,
Grant 1965/19. BW was supported in part by NSF IIS-1513616 and DBI-1661375. EM was
supported in part by NSF CMMI-1800466, DMS-1800446, and CCF-1907591.We would like
to thank the Institute for Mathematics and its Applications for hosting a workshop
titled Bridging Statistics and Sheaves in May 2018, where this work was conceived.\r\nOpen
Access funding provided by Institute of Science and Technology (IST Austria)."
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Adam
full_name: Brown, Adam
id: 70B7FDF6-608D-11E9-9333-8535E6697425
last_name: Brown
- first_name: Omer
full_name: Bobrowski, Omer
last_name: Bobrowski
- first_name: Elizabeth
full_name: Munch, Elizabeth
last_name: Munch
- first_name: Bei
full_name: Wang, Bei
last_name: Wang
citation:
ama: Brown A, Bobrowski O, Munch E, Wang B. Probabilistic convergence and stability
of random mapper graphs. Journal of Applied and Computational Topology.
2021;5(1):99-140. doi:10.1007/s41468-020-00063-x
apa: Brown, A., Bobrowski, O., Munch, E., & Wang, B. (2021). Probabilistic convergence
and stability of random mapper graphs. Journal of Applied and Computational
Topology. Springer Nature. https://doi.org/10.1007/s41468-020-00063-x
chicago: Brown, Adam, Omer Bobrowski, Elizabeth Munch, and Bei Wang. “Probabilistic
Convergence and Stability of Random Mapper Graphs.” Journal of Applied and
Computational Topology. Springer Nature, 2021. https://doi.org/10.1007/s41468-020-00063-x.
ieee: A. Brown, O. Bobrowski, E. Munch, and B. Wang, “Probabilistic convergence
and stability of random mapper graphs,” Journal of Applied and Computational
Topology, vol. 5, no. 1. Springer Nature, pp. 99–140, 2021.
ista: Brown A, Bobrowski O, Munch E, Wang B. 2021. Probabilistic convergence and
stability of random mapper graphs. Journal of Applied and Computational Topology.
5(1), 99–140.
mla: Brown, Adam, et al. “Probabilistic Convergence and Stability of Random Mapper
Graphs.” Journal of Applied and Computational Topology, vol. 5, no. 1,
Springer Nature, 2021, pp. 99–140, doi:10.1007/s41468-020-00063-x.
short: A. Brown, O. Bobrowski, E. Munch, B. Wang, Journal of Applied and Computational
Topology 5 (2021) 99–140.
date_created: 2021-02-11T14:41:02Z
date_published: 2021-03-01T00:00:00Z
date_updated: 2023-09-05T15:37:56Z
day: '01'
ddc:
- '510'
department:
- _id: HeEd
doi: 10.1007/s41468-020-00063-x
ec_funded: 1
external_id:
arxiv:
- '1909.03488'
file:
- access_level: open_access
checksum: 3f02e9d47c428484733da0f588a3c069
content_type: application/pdf
creator: dernst
date_created: 2021-02-11T14:43:59Z
date_updated: 2021-02-11T14:43:59Z
file_id: '9112'
file_name: 2020_JourApplCompTopology_Brown.pdf
file_size: 2090265
relation: main_file
success: 1
file_date_updated: 2021-02-11T14:43:59Z
has_accepted_license: '1'
intvolume: ' 5'
issue: '1'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 99-140
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Journal of Applied and Computational Topology
publication_identifier:
eissn:
- 2367-1734
issn:
- 2367-1726
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Probabilistic convergence and stability of random mapper graphs
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 5
year: '2021'
...
---
_id: '9252'
abstract:
- lang: eng
text: 'This paper analyses the conditions for local adaptation in a metapopulation
with infinitely many islands under a model of hard selection, where population
size depends on local fitness. Each island belongs to one of two distinct ecological
niches or habitats. Fitness is influenced by an additive trait which is under
habitat‐dependent directional selection. Our analysis is based on the diffusion
approximation and accounts for both genetic drift and demographic stochasticity.
By neglecting linkage disequilibria, it yields the joint distribution of allele
frequencies and population size on each island. We find that under hard selection,
the conditions for local adaptation in a rare habitat are more restrictive for
more polygenic traits: even moderate migration load per locus at very many loci
is sufficient for population sizes to decline. This further reduces the efficacy
of selection at individual loci due to increased drift and because smaller populations
are more prone to swamping due to migration, causing a positive feedback between
increasing maladaptation and declining population sizes. Our analysis also highlights
the importance of demographic stochasticity, which exacerbates the decline in
numbers of maladapted populations, leading to population collapse in the rare
habitat at significantly lower migration than predicted by deterministic arguments.'
acknowledgement: We thank the reviewers for their helpful comments, and also our colleagues,
for illuminating discussions over the long gestation of this paper.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Eniko
full_name: Szep, Eniko
id: 485BB5A4-F248-11E8-B48F-1D18A9856A87
last_name: Szep
- first_name: Himani
full_name: Sachdeva, Himani
id: 42377A0A-F248-11E8-B48F-1D18A9856A87
last_name: Sachdeva
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: 'Szep E, Sachdeva H, Barton NH. Polygenic local adaptation in metapopulations:
A stochastic eco‐evolutionary model. Evolution. 2021;75(5):1030-1045. doi:10.1111/evo.14210'
apa: 'Szep, E., Sachdeva, H., & Barton, N. H. (2021). Polygenic local adaptation
in metapopulations: A stochastic eco‐evolutionary model. Evolution. Wiley.
https://doi.org/10.1111/evo.14210'
chicago: 'Szep, Eniko, Himani Sachdeva, and Nicholas H Barton. “Polygenic Local
Adaptation in Metapopulations: A Stochastic Eco‐evolutionary Model.” Evolution.
Wiley, 2021. https://doi.org/10.1111/evo.14210.'
ieee: 'E. Szep, H. Sachdeva, and N. H. Barton, “Polygenic local adaptation in metapopulations:
A stochastic eco‐evolutionary model,” Evolution, vol. 75, no. 5. Wiley,
pp. 1030–1045, 2021.'
ista: 'Szep E, Sachdeva H, Barton NH. 2021. Polygenic local adaptation in metapopulations:
A stochastic eco‐evolutionary model. Evolution. 75(5), 1030–1045.'
mla: 'Szep, Eniko, et al. “Polygenic Local Adaptation in Metapopulations: A Stochastic
Eco‐evolutionary Model.” Evolution, vol. 75, no. 5, Wiley, 2021, pp. 1030–45,
doi:10.1111/evo.14210.'
short: E. Szep, H. Sachdeva, N.H. Barton, Evolution 75 (2021) 1030–1045.
date_created: 2021-03-20T08:22:10Z
date_published: 2021-05-01T00:00:00Z
date_updated: 2023-09-05T15:44:06Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1111/evo.14210
external_id:
isi:
- '000636966300001'
file:
- access_level: open_access
checksum: b90fb5767d623602046fed03725e16ca
content_type: application/pdf
creator: kschuh
date_created: 2021-08-11T13:39:19Z
date_updated: 2021-08-11T13:39:19Z
file_id: '9886'
file_name: 2021_Evolution_Szep.pdf
file_size: 734102
relation: main_file
success: 1
file_date_updated: 2021-08-11T13:39:19Z
has_accepted_license: '1'
intvolume: ' 75'
isi: 1
issue: '5'
keyword:
- Genetics
- Ecology
- Evolution
- Behavior and Systematics
- General Agricultural and Biological Sciences
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: 1030-1045
publication: Evolution
publication_identifier:
eissn:
- 1558-5646
issn:
- 0014-3820
publication_status: published
publisher: Wiley
quality_controlled: '1'
related_material:
record:
- id: '13062'
relation: research_data
status: public
scopus_import: '1'
status: public
title: 'Polygenic local adaptation in metapopulations: A stochastic eco‐evolutionary
model'
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 75
year: '2021'
...
---
_id: '9374'
abstract:
- lang: eng
text: If there are no constraints on the process of speciation, then the number
of species might be expected to match the number of available niches and this
number might be indefinitely large. One possible constraint is the opportunity
for allopatric divergence. In 1981, Felsenstein used a simple and elegant model
to ask if there might also be genetic constraints. He showed that progress towards
speciation could be described by the build‐up of linkage disequilibrium among
divergently selected loci and between these loci and those contributing to other
forms of reproductive isolation. Therefore, speciation is opposed by recombination,
because it tends to break down linkage disequilibria. Felsenstein then introduced
a crucial distinction between “two‐allele” models, which are subject to this effect,
and “one‐allele” models, which are free from the recombination constraint. These
fundamentally important insights have been the foundation for both empirical and
theoretical studies of speciation ever since.
acknowledgement: RKB was funded by the Natural Environment Research Council (NE/P012272/1
& NE/P001610/1), the European Research Council (693030 BARRIERS), and the Swedish
Research Council (VR) (2018‐03695). MRS was funded by the National Science Foundation
(Grant No. DEB1939290).
article_processing_charge: No
article_type: original
author:
- first_name: Roger K.
full_name: Butlin, Roger K.
last_name: Butlin
- first_name: Maria R.
full_name: Servedio, Maria R.
last_name: Servedio
- first_name: Carole M.
full_name: Smadja, Carole M.
last_name: Smadja
- first_name: Claudia
full_name: Bank, Claudia
last_name: Bank
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Samuel M.
full_name: Flaxman, Samuel M.
last_name: Flaxman
- first_name: Tatiana
full_name: Giraud, Tatiana
last_name: Giraud
- first_name: Robin
full_name: Hopkins, Robin
last_name: Hopkins
- first_name: Erica L.
full_name: Larson, Erica L.
last_name: Larson
- first_name: Martine E.
full_name: Maan, Martine E.
last_name: Maan
- first_name: Joana
full_name: Meier, Joana
last_name: Meier
- first_name: Richard
full_name: Merrill, Richard
last_name: Merrill
- first_name: Mohamed A. F.
full_name: Noor, Mohamed A. F.
last_name: Noor
- first_name: Daniel
full_name: Ortiz‐Barrientos, Daniel
last_name: Ortiz‐Barrientos
- first_name: Anna
full_name: Qvarnström, Anna
last_name: Qvarnström
citation:
ama: Butlin RK, Servedio MR, Smadja CM, et al. Homage to Felsenstein 1981, or why
are there so few/many species? Evolution. 2021;75(5):978-988. doi:10.1111/evo.14235
apa: Butlin, R. K., Servedio, M. R., Smadja, C. M., Bank, C., Barton, N. H., Flaxman,
S. M., … Qvarnström, A. (2021). Homage to Felsenstein 1981, or why are there so
few/many species? Evolution. Wiley. https://doi.org/10.1111/evo.14235
chicago: Butlin, Roger K., Maria R. Servedio, Carole M. Smadja, Claudia Bank, Nicholas
H Barton, Samuel M. Flaxman, Tatiana Giraud, et al. “Homage to Felsenstein 1981,
or Why Are There so Few/Many Species?” Evolution. Wiley, 2021. https://doi.org/10.1111/evo.14235.
ieee: R. K. Butlin et al., “Homage to Felsenstein 1981, or why are there
so few/many species?,” Evolution, vol. 75, no. 5. Wiley, pp. 978–988, 2021.
ista: Butlin RK, Servedio MR, Smadja CM, Bank C, Barton NH, Flaxman SM, Giraud T,
Hopkins R, Larson EL, Maan ME, Meier J, Merrill R, Noor MAF, Ortiz‐Barrientos
D, Qvarnström A. 2021. Homage to Felsenstein 1981, or why are there so few/many
species? Evolution. 75(5), 978–988.
mla: Butlin, Roger K., et al. “Homage to Felsenstein 1981, or Why Are There so Few/Many
Species?” Evolution, vol. 75, no. 5, Wiley, 2021, pp. 978–88, doi:10.1111/evo.14235.
short: R.K. Butlin, M.R. Servedio, C.M. Smadja, C. Bank, N.H. Barton, S.M. Flaxman,
T. Giraud, R. Hopkins, E.L. Larson, M.E. Maan, J. Meier, R. Merrill, M.A.F. Noor,
D. Ortiz‐Barrientos, A. Qvarnström, Evolution 75 (2021) 978–988.
date_created: 2021-05-06T04:34:47Z
date_published: 2021-04-19T00:00:00Z
date_updated: 2023-09-05T15:44:33Z
day: '19'
department:
- _id: NiBa
doi: 10.1111/evo.14235
external_id:
isi:
- '000647224000001'
intvolume: ' 75'
isi: 1
issue: '5'
keyword:
- Genetics
- Ecology
- Evolution
- Behavior and Systematics
- General Agricultural and Biological Sciences
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://onlinelibrary.wiley.com/doi/10.1111/evo.14235
month: '04'
oa: 1
oa_version: Published Version
page: 978-988
publication: Evolution
publication_identifier:
eissn:
- 1558-5646
issn:
- 0014-3820
publication_status: published
publisher: Wiley
quality_controlled: '1'
status: public
title: Homage to Felsenstein 1981, or why are there so few/many species?
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 75
year: '2021'
...
---
_id: '13062'
abstract:
- lang: eng
text: 'This paper analyzes the conditions for local adaptation in a metapopulation
with infinitely many islands under a model of hard selection, where population
size depends on local fitness. Each island belongs to one of two distinct ecological
niches or habitats. Fitness is influenced by an additive trait which is under
habitat-dependent directional selection. Our analysis is based on the diffusion
approximation and accounts for both genetic drift and demographic stochasticity.
By neglecting linkage disequilibria, it yields the joint distribution of allele
frequencies and population size on each island. We find that under hard selection,
the conditions for local adaptation in a rare habitat are more restrictive for
more polygenic traits: even moderate migration load per locus at very many loci
is sufficient for population sizes to decline. This further reduces the efficacy
of selection at individual loci due to increased drift and because smaller populations
are more prone to swamping due to migration, causing a positive feedback between
increasing maladaptation and declining population sizes. Our analysis also highlights
the importance of demographic stochasticity, which exacerbates the decline in
numbers of maladapted populations, leading to population collapse in the rare
habitat at significantly lower migration than predicted by deterministic arguments.'
article_processing_charge: No
author:
- first_name: Eniko
full_name: Szep, Eniko
id: 485BB5A4-F248-11E8-B48F-1D18A9856A87
last_name: Szep
- first_name: Himani
full_name: Sachdeva, Himani
id: 42377A0A-F248-11E8-B48F-1D18A9856A87
last_name: Sachdeva
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: 'Szep E, Sachdeva H, Barton NH. Supplementary code for: Polygenic local adaptation
in metapopulations: A stochastic eco-evolutionary model. 2021. doi:10.5061/DRYAD.8GTHT76P1'
apa: 'Szep, E., Sachdeva, H., & Barton, N. H. (2021). Supplementary code for:
Polygenic local adaptation in metapopulations: A stochastic eco-evolutionary model.
Dryad. https://doi.org/10.5061/DRYAD.8GTHT76P1'
chicago: 'Szep, Eniko, Himani Sachdeva, and Nicholas H Barton. “Supplementary Code
for: Polygenic Local Adaptation in Metapopulations: A Stochastic Eco-Evolutionary
Model.” Dryad, 2021. https://doi.org/10.5061/DRYAD.8GTHT76P1.'
ieee: 'E. Szep, H. Sachdeva, and N. H. Barton, “Supplementary code for: Polygenic
local adaptation in metapopulations: A stochastic eco-evolutionary model.” Dryad,
2021.'
ista: 'Szep E, Sachdeva H, Barton NH. 2021. Supplementary code for: Polygenic local
adaptation in metapopulations: A stochastic eco-evolutionary model, Dryad, 10.5061/DRYAD.8GTHT76P1.'
mla: 'Szep, Eniko, et al. Supplementary Code for: Polygenic Local Adaptation
in Metapopulations: A Stochastic Eco-Evolutionary Model. Dryad, 2021, doi:10.5061/DRYAD.8GTHT76P1.'
short: E. Szep, H. Sachdeva, N.H. Barton, (2021).
date_created: 2023-05-23T16:17:02Z
date_published: 2021-03-02T00:00:00Z
date_updated: 2023-09-05T15:44:05Z
day: '02'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.5061/DRYAD.8GTHT76P1
license: https://creativecommons.org/publicdomain/zero/1.0/
main_file_link:
- open_access: '1'
url: https://doi.org/10.5061/dryad.8gtht76p1
month: '03'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
record:
- id: '9252'
relation: used_in_publication
status: public
status: public
title: 'Supplementary code for: Polygenic local adaptation in metapopulations: A stochastic
eco-evolutionary model'
tmp:
image: /images/cc_0.png
legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
name: Creative Commons Public Domain Dedication (CC0 1.0)
short: CC0 (1.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '10838'
abstract:
- lang: eng
text: Combining hybrid zone analysis with genomic data is a promising approach to
understanding the genomic basis of adaptive divergence. It allows for the identification
of genomic regions underlying barriers to gene flow. It also provides insights
into spatial patterns of allele frequency change, informing about the interplay
between environmental factors, dispersal and selection. However, when only a single
hybrid zone is analysed, it is difficult to separate patterns generated by selection
from those resulting from chance. Therefore, it is beneficial to look for repeatable
patterns across replicate hybrid zones in the same system. We applied this approach
to the marine snail Littorina saxatilis, which contains two ecotypes, adapted
to wave-exposed rocks vs. high-predation boulder fields. The existence of numerous
hybrid zones between ecotypes offered the opportunity to test for the repeatability
of genomic architectures and spatial patterns of divergence. We sampled and phenotyped
snails from seven replicate hybrid zones on the Swedish west coast and genotyped
them for thousands of single nucleotide polymorphisms. Shell shape and size showed
parallel clines across all zones. Many genomic regions showing steep clines and/or
high differentiation were shared among hybrid zones, consistent with a common
evolutionary history and extensive gene flow between zones, and supporting the
importance of these regions for divergence. In particular, we found that several
large putative inversions contribute to divergence in all locations. Additionally,
we found evidence for consistent displacement of clines from the boulder–rock
transition. Our results demonstrate patterns of spatial variation that would not
be accessible without continuous spatial sampling, a large genomic data set and
replicate hybrid zones.
acknowledgement: "We thank everyone who helped with fieldwork, snail processing and
DNA extractions, particularly Laura Brettell, Mårten Duvetorp, Juan Galindo, Anne-Lise
Liabot, Mark Ravinet, Irena Senčić and Zuzanna Zagrodzka. We are also grateful to
Edinburgh Genomics for library preparation and sequencing, to Stuart Baird and Mark
Ravinet for helpful discussions, and to three anonymous reviewers for their constructive
comments. This work was supported by the Natural Environment Research Council (NE/K014021/1),
the European Research Council (AdG-693030-BARRIERS), Swedish Research Councils Formas
and Vetenskapsrådet through a Linnaeus grant to the Centre for Marine Evolutionary
Biology (217-2008-1719), the European Regional Development Fund (POCI-01-0145-FEDER-030628),
and the Fundação para a iência e a Tecnologia,\r\nPortugal (PTDC/BIA-EVL/\r\n30628/2017).
A.M.W. and R.F. were\r\nfunded by the European Union’s Horizon 2020 research and
innovation\r\nprogramme under Marie Skłodowska-Curie\r\ngrant agreements\r\nno.
754411/797747 and no. 706376, respectively."
article_processing_charge: No
article_type: original
author:
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Rui
full_name: Faria, Rui
last_name: Faria
- first_name: Kerstin
full_name: Johannesson, Kerstin
last_name: Johannesson
- first_name: Roger
full_name: Butlin, Roger
last_name: Butlin
citation:
ama: Westram AM, Faria R, Johannesson K, Butlin R. Using replicate hybrid zones
to understand the genomic basis of adaptive divergence. Molecular Ecology.
2021;30(15):3797-3814. doi:10.1111/mec.15861
apa: Westram, A. M., Faria, R., Johannesson, K., & Butlin, R. (2021). Using
replicate hybrid zones to understand the genomic basis of adaptive divergence.
Molecular Ecology. Wiley. https://doi.org/10.1111/mec.15861
chicago: Westram, Anja M, Rui Faria, Kerstin Johannesson, and Roger Butlin. “Using
Replicate Hybrid Zones to Understand the Genomic Basis of Adaptive Divergence.”
Molecular Ecology. Wiley, 2021. https://doi.org/10.1111/mec.15861.
ieee: A. M. Westram, R. Faria, K. Johannesson, and R. Butlin, “Using replicate hybrid
zones to understand the genomic basis of adaptive divergence,” Molecular Ecology,
vol. 30, no. 15. Wiley, pp. 3797–3814, 2021.
ista: Westram AM, Faria R, Johannesson K, Butlin R. 2021. Using replicate hybrid
zones to understand the genomic basis of adaptive divergence. Molecular Ecology.
30(15), 3797–3814.
mla: Westram, Anja M., et al. “Using Replicate Hybrid Zones to Understand the Genomic
Basis of Adaptive Divergence.” Molecular Ecology, vol. 30, no. 15, Wiley,
2021, pp. 3797–814, doi:10.1111/mec.15861.
short: A.M. Westram, R. Faria, K. Johannesson, R. Butlin, Molecular Ecology 30 (2021)
3797–3814.
date_created: 2022-03-08T11:28:32Z
date_published: 2021-08-01T00:00:00Z
date_updated: 2023-09-05T16:02:19Z
day: '01'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1111/mec.15861
external_id:
isi:
- '000669439700001'
pmid:
- '33638231'
file:
- access_level: open_access
checksum: d5611f243ceb63a0e091d6662ebd9cda
content_type: application/pdf
creator: dernst
date_created: 2022-03-08T11:31:30Z
date_updated: 2022-03-08T11:31:30Z
file_id: '10839'
file_name: 2021_MolecularEcology_Westram.pdf
file_size: 1726548
relation: main_file
success: 1
file_date_updated: 2022-03-08T11:31:30Z
has_accepted_license: '1'
intvolume: ' 30'
isi: 1
issue: '15'
keyword:
- Genetics
- Ecology
- Evolution
- Behavior and Systematics
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 3797-3814
pmid: 1
publication: Molecular Ecology
publication_identifier:
eissn:
- 1365-294X
issn:
- 0962-1083
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Using replicate hybrid zones to understand the genomic basis of adaptive divergence
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 30
year: '2021'
...
---
_id: '9288'
abstract:
- lang: eng
text: "• The phenylpropanoid pathway serves a central role in plant metabolism,
providing numerous compounds involved in diverse physiological processes. Most
carbon entering the pathway is incorporated into lignin. Although several phenylpropanoid
pathway mutants show seedling growth arrest, the role for lignin in seedling growth
and development is unexplored.\r\n• We use complementary pharmacological and genetic
approaches to block CINNAMATE‐4‐HYDROXYLASE (C4H) functionality in Arabidopsis
seedlings and a set of molecular and biochemical techniques to investigate the
underlying phenotypes.\r\n• Blocking C4H resulted in reduced lateral rooting and
increased adventitious rooting apically in the hypocotyl. These phenotypes coincided
with an inhibition in auxin transport. The upstream accumulation in cis‐cinnamic
acid was found to likely cause polar auxin transport inhibition. Conversely, a
downstream depletion in lignin perturbed phloem‐mediated auxin transport. Restoring
lignin deposition effectively reestablished phloem transport and, accordingly,
auxin homeostasis.\r\n• Our results show that the accumulation of bioactive intermediates
and depletion in lignin jointly cause the aberrant phenotypes upon blocking C4H,
and demonstrate that proper deposition of lignin is essential for the establishment
of auxin distribution in seedlings. Our data position the phenylpropanoid pathway
and lignin in a new physiological framework, consolidating their importance in
plant growth and development."
article_processing_charge: No
article_type: original
author:
- first_name: I
full_name: El Houari, I
last_name: El Houari
- first_name: C
full_name: Van Beirs, C
last_name: Van Beirs
- first_name: HE
full_name: Arents, HE
last_name: Arents
- first_name: Huibin
full_name: Han, Huibin
id: 31435098-F248-11E8-B48F-1D18A9856A87
last_name: Han
- first_name: A
full_name: Chanoca, A
last_name: Chanoca
- first_name: D
full_name: Opdenacker, D
last_name: Opdenacker
- first_name: J
full_name: Pollier, J
last_name: Pollier
- first_name: V
full_name: Storme, V
last_name: Storme
- first_name: W
full_name: Steenackers, W
last_name: Steenackers
- first_name: M
full_name: Quareshy, M
last_name: Quareshy
- first_name: R
full_name: Napier, R
last_name: Napier
- first_name: T
full_name: Beeckman, T
last_name: Beeckman
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: B
full_name: De Rybel, B
last_name: De Rybel
- first_name: W
full_name: Boerjan, W
last_name: Boerjan
- first_name: B
full_name: Vanholme, B
last_name: Vanholme
citation:
ama: El Houari I, Van Beirs C, Arents H, et al. Seedling developmental defects upon
blocking CINNAMATE-4-HYDROXYLASE are caused by perturbations in auxin transport.
New Phytologist. 2021;230(6):2275-2291. doi:10.1111/nph.17349
apa: El Houari, I., Van Beirs, C., Arents, H., Han, H., Chanoca, A., Opdenacker,
D., … Vanholme, B. (2021). Seedling developmental defects upon blocking CINNAMATE-4-HYDROXYLASE
are caused by perturbations in auxin transport. New Phytologist. Wiley.
https://doi.org/10.1111/nph.17349
chicago: El Houari, I, C Van Beirs, HE Arents, Huibin Han, A Chanoca, D Opdenacker,
J Pollier, et al. “Seedling Developmental Defects upon Blocking CINNAMATE-4-HYDROXYLASE
Are Caused by Perturbations in Auxin Transport.” New Phytologist. Wiley,
2021. https://doi.org/10.1111/nph.17349.
ieee: I. El Houari et al., “Seedling developmental defects upon blocking
CINNAMATE-4-HYDROXYLASE are caused by perturbations in auxin transport,” New
Phytologist, vol. 230, no. 6. Wiley, pp. 2275–2291, 2021.
ista: El Houari I, Van Beirs C, Arents H, Han H, Chanoca A, Opdenacker D, Pollier
J, Storme V, Steenackers W, Quareshy M, Napier R, Beeckman T, Friml J, De Rybel
B, Boerjan W, Vanholme B. 2021. Seedling developmental defects upon blocking CINNAMATE-4-HYDROXYLASE
are caused by perturbations in auxin transport. New Phytologist. 230(6), 2275–2291.
mla: El Houari, I., et al. “Seedling Developmental Defects upon Blocking CINNAMATE-4-HYDROXYLASE
Are Caused by Perturbations in Auxin Transport.” New Phytologist, vol.
230, no. 6, Wiley, 2021, pp. 2275–91, doi:10.1111/nph.17349.
short: I. El Houari, C. Van Beirs, H. Arents, H. Han, A. Chanoca, D. Opdenacker,
J. Pollier, V. Storme, W. Steenackers, M. Quareshy, R. Napier, T. Beeckman, J.
Friml, B. De Rybel, W. Boerjan, B. Vanholme, New Phytologist 230 (2021) 2275–2291.
date_created: 2021-03-26T12:09:01Z
date_published: 2021-03-17T00:00:00Z
date_updated: 2023-09-05T15:46:55Z
day: '17'
department:
- _id: JiFr
doi: 10.1111/nph.17349
external_id:
isi:
- '000639552400001'
pmid:
- '33728703'
intvolume: ' 230'
isi: 1
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://biblio.ugent.be/publication/8703799/file/8703800.pdf
month: '03'
oa: 1
oa_version: Published Version
page: 2275-2291
pmid: 1
publication: New Phytologist
publication_identifier:
eissn:
- 1469-8137
issn:
- 0028-646x
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Seedling developmental defects upon blocking CINNAMATE-4-HYDROXYLASE are caused
by perturbations in auxin transport
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 230
year: '2021'
...
---
_id: '10836'
acknowledgement: This work was supported by the Austrian Science Fund (FWF) grants MCCA W1248-B30 and SFB F4606-B28 to EJJ. CP received a short-term
research fellowship of the European Federation of Immunological Societies (EFIS-IL) for a research visit at Biocruces Bizkaia Health Research Institute, Barakaldo, Spain. VKK received an EFIS-IL short-term research fellowship for a research visit at King’s College London. The
research was funded by the National Institute for Health Research (NIHR) Biomedical
Research Centre (BRC) based at Guy's and St Thomas' NHS Foundation Trust and King's
College London (IS-BRC-1215-20006) (SNK). The authors acknowledge support by the Medical Research Council
(MR/L023091/1) (SNK); Breast Cancer Now (147; KCL-BCN-Q3)(SNK); Cancer Research
UK (C30122/A11527; C30122/A15774) (SNK); Cancer Research UK King's Health Partners Centre at King's College London (C604/A25135) (SNK); CRUK/NIHR in England/DoH for Scotland, Wales and Northern Ireland Experimental Cancer Medicine Centre (C10355/A15587) (SNK). The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health. Additionally, this work was funded by Instituto de Salud Carlos III through the project "PI16/01223" (Co-funded by European
Regional Development Fund; “A way to make Europe”) to FB and by the Department of Health, Basque Government through the project
“2019111031” to OZ. OZ is recipient of a Sara Borrell 2017 post-doctoral contract
“CD17/00128” funded by Instituto de Salud Carlos III (Co-funded by European Social
Fund; “Investing in your future”).
article_processing_charge: No
article_type: letter_note
author:
- first_name: Christina L.
full_name: Pranger, Christina L.
last_name: Pranger
- first_name: Judit
full_name: Fazekas-Singer, Judit
id: 36432834-F248-11E8-B48F-1D18A9856A87
last_name: Fazekas-Singer
orcid: 0000-0002-8777-3502
- first_name: Verena K.
full_name: Köhler, Verena K.
last_name: Köhler
- first_name: Isabella
full_name: Pali‐Schöll, Isabella
last_name: Pali‐Schöll
- first_name: Alessandro
full_name: Fiocchi, Alessandro
last_name: Fiocchi
- first_name: Sophia N.
full_name: Karagiannis, Sophia N.
last_name: Karagiannis
- first_name: Olatz
full_name: Zenarruzabeitia, Olatz
last_name: Zenarruzabeitia
- first_name: Francisco
full_name: Borrego, Francisco
last_name: Borrego
- first_name: Erika
full_name: Jensen‐Jarolim, Erika
last_name: Jensen‐Jarolim
citation:
ama: 'Pranger CL, Singer J, Köhler VK, et al. PIPE‐cloned human IgE and IgG4 antibodies:
New tools for investigating cow’s milk allergy and tolerance. Allergy.
2021;76(5):1553-1556. doi:10.1111/all.14604'
apa: 'Pranger, C. L., Singer, J., Köhler, V. K., Pali‐Schöll, I., Fiocchi, A., Karagiannis,
S. N., … Jensen‐Jarolim, E. (2021). PIPE‐cloned human IgE and IgG4 antibodies:
New tools for investigating cow’s milk allergy and tolerance. Allergy.
Wiley. https://doi.org/10.1111/all.14604'
chicago: 'Pranger, Christina L., Judit Singer, Verena K. Köhler, Isabella Pali‐Schöll,
Alessandro Fiocchi, Sophia N. Karagiannis, Olatz Zenarruzabeitia, Francisco Borrego,
and Erika Jensen‐Jarolim. “PIPE‐cloned Human IgE and IgG4 Antibodies: New Tools
for Investigating Cow’s Milk Allergy and Tolerance.” Allergy. Wiley, 2021.
https://doi.org/10.1111/all.14604.'
ieee: 'C. L. Pranger et al., “PIPE‐cloned human IgE and IgG4 antibodies:
New tools for investigating cow’s milk allergy and tolerance,” Allergy,
vol. 76, no. 5. Wiley, pp. 1553–1556, 2021.'
ista: 'Pranger CL, Singer J, Köhler VK, Pali‐Schöll I, Fiocchi A, Karagiannis SN,
Zenarruzabeitia O, Borrego F, Jensen‐Jarolim E. 2021. PIPE‐cloned human IgE and
IgG4 antibodies: New tools for investigating cow’s milk allergy and tolerance.
Allergy. 76(5), 1553–1556.'
mla: 'Pranger, Christina L., et al. “PIPE‐cloned Human IgE and IgG4 Antibodies:
New Tools for Investigating Cow’s Milk Allergy and Tolerance.” Allergy,
vol. 76, no. 5, Wiley, 2021, pp. 1553–56, doi:10.1111/all.14604.'
short: C.L. Pranger, J. Singer, V.K. Köhler, I. Pali‐Schöll, A. Fiocchi, S.N. Karagiannis,
O. Zenarruzabeitia, F. Borrego, E. Jensen‐Jarolim, Allergy 76 (2021) 1553–1556.
date_created: 2022-03-08T11:19:05Z
date_published: 2021-05-01T00:00:00Z
date_updated: 2023-09-05T15:58:53Z
day: '01'
ddc:
- '570'
department:
- _id: Bio
doi: 10.1111/all.14604
external_id:
isi:
- '000577708800001'
pmid:
- '32990982'
file:
- access_level: open_access
checksum: 9526f9554112fc027c9f7fa540c488cd
content_type: application/pdf
creator: dernst
date_created: 2022-03-08T11:23:16Z
date_updated: 2022-03-08T11:23:16Z
file_id: '10837'
file_name: 2021_Allergy_Pranger.pdf
file_size: 626081
relation: main_file
success: 1
file_date_updated: 2022-03-08T11:23:16Z
has_accepted_license: '1'
intvolume: ' 76'
isi: 1
issue: '5'
keyword:
- Immunology
- Immunology and Allergy
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: 1553-1556
pmid: 1
publication: Allergy
publication_identifier:
eissn:
- 1398-9995
issn:
- 0105-4538
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'PIPE‐cloned human IgE and IgG4 antibodies: New tools for investigating cow''s
milk allergy and tolerance'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 76
year: '2021'
...
---
_id: '8608'
abstract:
- lang: eng
text: To adapt to the diverse array of biotic and abiotic cues, plants have evolved
sophisticated mechanisms to sense changes in environmental conditions and modulate
their growth. Growth-promoting hormones and defence signalling fine tune plant
development antagonistically. During host-pathogen interactions, this defence-growth
trade-off is mediated by the counteractive effects of the defence hormone salicylic
acid (SA) and the growth hormone auxin. Here we revealed an underlying mechanism
of SA regulating auxin signalling by constraining the plasma membrane dynamics
of PIN2 auxin efflux transporter in Arabidopsis thaliana roots. The lateral diffusion
of PIN2 proteins is constrained by SA signalling, during which PIN2 proteins are
condensed into hyperclusters depending on REM1.2-mediated nanodomain compartmentalisation.
Furthermore, membrane nanodomain compartmentalisation by SA or Remorin (REM) assembly
significantly suppressed clathrin-mediated endocytosis. Consequently, SA-induced
heterogeneous surface condensation disrupted asymmetric auxin distribution and
the resultant gravitropic response. Our results demonstrated a defence-growth
trade-off mechanism by which SA signalling crosstalked with auxin transport by
concentrating membrane-resident PIN2 into heterogeneous compartments.
acknowledgement: This work was supported by the National Key Research andDevelopment
Programme of China (2017YFA0506100), theNational Natural Science Foundation of China
(31870170 and31701168), and the Fok Ying Tung Education Foundation(161027) to XC;
NTU startup grant (M4081533) and NIM/01/2016 (NTU, Singapore) to YM. We thank Lei
Shi andZhongquan Lin for microscopy assistance.
article_processing_charge: No
article_type: original
author:
- first_name: M
full_name: Ke, M
last_name: Ke
- first_name: Z
full_name: Ma, Z
last_name: Ma
- first_name: D
full_name: Wang, D
last_name: Wang
- first_name: Y
full_name: Sun, Y
last_name: Sun
- first_name: C
full_name: Wen, C
last_name: Wen
- first_name: D
full_name: Huang, D
last_name: Huang
- first_name: Z
full_name: Chen, Z
last_name: Chen
- first_name: L
full_name: Yang, L
last_name: Yang
- first_name: Shutang
full_name: Tan, Shutang
id: 2DE75584-F248-11E8-B48F-1D18A9856A87
last_name: Tan
orcid: 0000-0002-0471-8285
- first_name: R
full_name: Li, R
last_name: Li
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Y
full_name: Miao, Y
last_name: Miao
- first_name: X
full_name: Chen, X
last_name: Chen
citation:
ama: Ke M, Ma Z, Wang D, et al. Salicylic acid regulates PIN2 auxin transporter
hyper-clustering and root gravitropic growth via Remorin-dependent lipid nanodomain
organization in Arabidopsis thaliana. New Phytologist. 2021;229(2):963-978.
doi:10.1111/nph.16915
apa: Ke, M., Ma, Z., Wang, D., Sun, Y., Wen, C., Huang, D., … Chen, X. (2021). Salicylic
acid regulates PIN2 auxin transporter hyper-clustering and root gravitropic growth
via Remorin-dependent lipid nanodomain organization in Arabidopsis thaliana. New
Phytologist. Wiley. https://doi.org/10.1111/nph.16915
chicago: Ke, M, Z Ma, D Wang, Y Sun, C Wen, D Huang, Z Chen, et al. “Salicylic Acid
Regulates PIN2 Auxin Transporter Hyper-Clustering and Root Gravitropic Growth
via Remorin-Dependent Lipid Nanodomain Organization in Arabidopsis Thaliana.”
New Phytologist. Wiley, 2021. https://doi.org/10.1111/nph.16915.
ieee: M. Ke et al., “Salicylic acid regulates PIN2 auxin transporter hyper-clustering
and root gravitropic growth via Remorin-dependent lipid nanodomain organization
in Arabidopsis thaliana,” New Phytologist, vol. 229, no. 2. Wiley, pp.
963–978, 2021.
ista: Ke M, Ma Z, Wang D, Sun Y, Wen C, Huang D, Chen Z, Yang L, Tan S, Li R, Friml
J, Miao Y, Chen X. 2021. Salicylic acid regulates PIN2 auxin transporter hyper-clustering
and root gravitropic growth via Remorin-dependent lipid nanodomain organization
in Arabidopsis thaliana. New Phytologist. 229(2), 963–978.
mla: Ke, M., et al. “Salicylic Acid Regulates PIN2 Auxin Transporter Hyper-Clustering
and Root Gravitropic Growth via Remorin-Dependent Lipid Nanodomain Organization
in Arabidopsis Thaliana.” New Phytologist, vol. 229, no. 2, Wiley, 2021,
pp. 963–78, doi:10.1111/nph.16915.
short: M. Ke, Z. Ma, D. Wang, Y. Sun, C. Wen, D. Huang, Z. Chen, L. Yang, S. Tan,
R. Li, J. Friml, Y. Miao, X. Chen, New Phytologist 229 (2021) 963–978.
date_created: 2020-10-05T12:45:36Z
date_published: 2021-01-01T00:00:00Z
date_updated: 2023-09-05T16:06:24Z
day: '01'
ddc:
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department:
- _id: JiFr
doi: 10.1111/nph.16915
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title: Salicylic acid regulates PIN2 auxin transporter hyper-clustering and root gravitropic
growth via Remorin-dependent lipid nanodomain organization in Arabidopsis thaliana
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