[{"publist_id":"7777","author":[{"full_name":"Shi, Chun Lin","last_name":"Shi","first_name":"Chun Lin"},{"first_name":"Daniel","id":"49E91952-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6862-1247","full_name":"Von Wangenheim, Daniel","last_name":"Von Wangenheim"},{"last_name":"Herrmann","full_name":"Herrmann, Ullrich","first_name":"Ullrich"},{"last_name":"Wildhagen","full_name":"Wildhagen, Mari","first_name":"Mari"},{"first_name":"Ivan","id":"F0AB3FCE-02D1-11E9-BD0E-99399A5D3DEB","full_name":"Kulik, Ivan","last_name":"Kulik"},{"last_name":"Kopf","full_name":"Kopf, Andreas","first_name":"Andreas"},{"last_name":"Ishida","full_name":"Ishida, Takashi","first_name":"Takashi"},{"full_name":"Olsson, Vilde","last_name":"Olsson","first_name":"Vilde"},{"first_name":"Mari Kristine","full_name":"Anker, Mari Kristine","last_name":"Anker"},{"first_name":"Markus","last_name":"Albert","full_name":"Albert, Markus"},{"last_name":"Butenko","full_name":"Butenko, Melinka A","first_name":"Melinka A"},{"first_name":"Georg","last_name":"Felix","full_name":"Felix, Georg"},{"first_name":"Shinichiro","full_name":"Sawa, Shinichiro","last_name":"Sawa"},{"first_name":"Manfred","last_name":"Claassen","full_name":"Claassen, Manfred"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","first_name":"Jirí","orcid":"0000-0002-8302-7596","full_name":"Friml, Jirí","last_name":"Friml"},{"last_name":"Aalen","full_name":"Aalen, Reidunn B","first_name":"Reidunn B"}],"article_processing_charge":"No","external_id":{"isi":["000443861300016"],"pmid":["30061750"]},"title":"The dynamics of root cap sloughing in Arabidopsis is regulated by peptide signalling","citation":{"ista":"Shi CL, von Wangenheim D, Herrmann U, Wildhagen M, Kulik I, Kopf A, Ishida T, Olsson V, Anker MK, Albert M, Butenko MA, Felix G, Sawa S, Claassen M, Friml J, Aalen RB. 2018. The dynamics of root cap sloughing in Arabidopsis is regulated by peptide signalling. Nature Plants. 4(8), 596–604.","chicago":"Shi, Chun Lin, Daniel von Wangenheim, Ullrich Herrmann, Mari Wildhagen, Ivan Kulik, Andreas Kopf, Takashi Ishida, et al. “The Dynamics of Root Cap Sloughing in Arabidopsis Is Regulated by Peptide Signalling.” Nature Plants. Nature Publishing Group, 2018. https://doi.org/10.1038/s41477-018-0212-z.","apa":"Shi, C. L., von Wangenheim, D., Herrmann, U., Wildhagen, M., Kulik, I., Kopf, A., … Aalen, R. B. (2018). The dynamics of root cap sloughing in Arabidopsis is regulated by peptide signalling. Nature Plants. Nature Publishing Group. https://doi.org/10.1038/s41477-018-0212-z","ama":"Shi CL, von Wangenheim D, Herrmann U, et al. The dynamics of root cap sloughing in Arabidopsis is regulated by peptide signalling. Nature Plants. 2018;4(8):596-604. doi:10.1038/s41477-018-0212-z","ieee":"C. L. Shi et al., “The dynamics of root cap sloughing in Arabidopsis is regulated by peptide signalling,” Nature Plants, vol. 4, no. 8. Nature Publishing Group, pp. 596–604, 2018.","short":"C.L. Shi, D. von Wangenheim, U. Herrmann, M. Wildhagen, I. Kulik, A. Kopf, T. Ishida, V. Olsson, M.K. Anker, M. Albert, M.A. Butenko, G. Felix, S. Sawa, M. Claassen, J. Friml, R.B. Aalen, Nature Plants 4 (2018) 596–604.","mla":"Shi, Chun Lin, et al. “The Dynamics of Root Cap Sloughing in Arabidopsis Is Regulated by Peptide Signalling.” Nature Plants, vol. 4, no. 8, Nature Publishing Group, 2018, pp. 596–604, doi:10.1038/s41477-018-0212-z."},"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","page":"596 - 604","date_published":"2018-07-30T00:00:00Z","doi":"10.1038/s41477-018-0212-z","date_created":"2018-12-11T11:44:52Z","has_accepted_license":"1","isi":1,"year":"2018","day":"30","publication":"Nature Plants","quality_controlled":"1","publisher":"Nature Publishing Group","oa":1,"department":[{"_id":"JiFr"}],"file_date_updated":"2020-07-14T12:44:56Z","date_updated":"2023-09-19T10:08:45Z","ddc":["580"],"type":"journal_article","article_type":"original","status":"public","_id":"146","volume":4,"issue":"8","related_material":{"link":[{"relation":"press_release","url":"https://ist.ac.at/en/news/new-process-in-root-development-discovered/","description":"News on IST Homepage"}]},"publication_status":"published","file":[{"checksum":"da33101c76ee1b2dc5ab28fd2ccba9d0","file_id":"7043","access_level":"open_access","relation":"main_file","content_type":"application/pdf","date_created":"2019-11-18T16:24:07Z","file_name":"2018_NaturePlants_Shi.pdf","creator":"dernst","date_updated":"2020-07-14T12:44:56Z","file_size":226829}],"language":[{"iso":"eng"}],"scopus_import":"1","month":"07","intvolume":" 4","abstract":[{"text":"The root cap protects the stem cell niche of angiosperm roots from damage. In Arabidopsis, lateral root cap (LRC) cells covering the meristematic zone are regularly lost through programmed cell death, while the outermost layer of the root cap covering the tip is repeatedly sloughed. Efficient coordination with stem cells producing new layers is needed to maintain a constant size of the cap. We present a signalling pair, the peptide IDA-LIKE1 (IDL1) and its receptor HAESA-LIKE2 (HSL2), mediating such communication. Live imaging over several days characterized this process from initial fractures in LRC cell files to full separation of a layer. Enhanced expression of IDL1 in the separating root cap layers resulted in increased frequency of sloughing, balanced with generation of new layers in a HSL2-dependent manner. Transcriptome analyses linked IDL1-HSL2 signalling to the transcription factors BEARSKIN1/2 and genes associated with programmed cell death. Mutations in either IDL1 or HSL2 slowed down cell division, maturation and separation. Thus, IDL1-HSL2 signalling potentiates dynamic regulation of the homeostatic balance between stem cell division and sloughing activity.","lang":"eng"}],"pmid":1,"oa_version":"Submitted Version"},{"acknowledgement":"This work was supported by a grant from the John Templeton Foundation and by the Office of Naval Research Grant N00014-16-1-2914 (M.A.N.). C.H. acknowledges generous support from the ISTFELLOW programme and by the Schrödinger scholarship of the Austrian Science Fund (FWF) J3475.","quality_controlled":"1","publisher":"Nature Publishing Group","oa":1,"day":"28","publication":"Nature Human Behaviour","has_accepted_license":"1","isi":1,"year":"2018","doi":"10.1038/s41562-018-0354-z","date_published":"2018-05-28T00:00:00Z","date_created":"2018-12-11T11:45:39Z","page":"397 - 404","project":[{"_id":"25681D80-B435-11E9-9278-68D0E5697425","call_identifier":"FP7","grant_number":"291734","name":"International IST Postdoc Fellowship Programme"}],"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"mla":"Hoffman, Moshe, et al. “The Signal-Burying Game Can Explain Why We Obscure Positive Traits and Good Deeds.” Nature Human Behaviour, vol. 2, Nature Publishing Group, 2018, pp. 397–404, doi:10.1038/s41562-018-0354-z.","ieee":"M. Hoffman, C. Hilbe, and M. Nowak, “The signal-burying game can explain why we obscure positive traits and good deeds,” Nature Human Behaviour, vol. 2. Nature Publishing Group, pp. 397–404, 2018.","short":"M. Hoffman, C. Hilbe, M. Nowak, Nature Human Behaviour 2 (2018) 397–404.","ama":"Hoffman M, Hilbe C, Nowak M. The signal-burying game can explain why we obscure positive traits and good deeds. Nature Human Behaviour. 2018;2:397-404. doi:10.1038/s41562-018-0354-z","apa":"Hoffman, M., Hilbe, C., & Nowak, M. (2018). The signal-burying game can explain why we obscure positive traits and good deeds. Nature Human Behaviour. Nature Publishing Group. https://doi.org/10.1038/s41562-018-0354-z","chicago":"Hoffman, Moshe, Christian Hilbe, and Martin Nowak. “The Signal-Burying Game Can Explain Why We Obscure Positive Traits and Good Deeds.” Nature Human Behaviour. Nature Publishing Group, 2018. https://doi.org/10.1038/s41562-018-0354-z.","ista":"Hoffman M, Hilbe C, Nowak M. 2018. The signal-burying game can explain why we obscure positive traits and good deeds. Nature Human Behaviour. 2, 397–404."},"title":"The signal-burying game can explain why we obscure positive traits and good deeds","publist_id":"7588","author":[{"first_name":"Moshe","full_name":"Hoffman, Moshe","last_name":"Hoffman"},{"orcid":"0000-0001-5116-955X","full_name":"Hilbe, Christian","last_name":"Hilbe","first_name":"Christian","id":"2FDF8F3C-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Martin","full_name":"Nowak, Martin","last_name":"Nowak"}],"article_processing_charge":"No","external_id":{"isi":["000435551300009"]},"oa_version":"Submitted Version","abstract":[{"text":"People sometimes make their admirable deeds and accomplishments hard to spot, such as by giving anonymously or avoiding bragging. Such ‘buried’ signals are hard to reconcile with standard models of signalling or indirect reciprocity, which motivate costly pro-social behaviour by reputational gains. To explain these phenomena, we design a simple game theory model, which we call the signal-burying game. This game has the feature that senders can bury their signal by deliberately reducing the probability of the signal being observed. If the signal is observed, however, it is identified as having been buried. We show under which conditions buried signals can be maintained, using static equilibrium concepts and calculations of the evolutionary dynamics. We apply our analysis to shed light on a number of otherwise puzzling social phenomena, including modesty, anonymous donations, subtlety in art and fashion, and overeagerness.","lang":"eng"}],"month":"05","intvolume":" 2","scopus_import":"1","file":[{"file_name":"2018_NatureHumanBeh_Hoffman.pdf","date_created":"2019-11-19T08:17:23Z","creator":"dernst","file_size":194734,"date_updated":"2020-07-14T12:45:54Z","file_id":"7051","checksum":"32efaf06a597495c184df91b3fbb19c0","relation":"main_file","access_level":"open_access","content_type":"application/pdf"}],"language":[{"iso":"eng"}],"publication_status":"published","related_material":{"link":[{"relation":"press_release","url":"https://ist.ac.at/en/news/the-logic-of-modesty-why-it-pays-to-be-humble/","description":"News on IST Homepage"}]},"volume":2,"ec_funded":1,"_id":"293","status":"public","article_type":"original","type":"journal_article","ddc":["000"],"date_updated":"2023-09-19T10:12:03Z","file_date_updated":"2020-07-14T12:45:54Z","department":[{"_id":"KrCh"}]},{"language":[{"iso":"eng"}],"file":[{"date_updated":"2020-07-14T12:46:31Z","file_size":923252,"creator":"system","date_created":"2018-12-12T10:11:57Z","file_name":"IST-2018-993-v1+1_2018_Benedikter_Dirac.pdf","content_type":"application/pdf","access_level":"open_access","relation":"main_file","file_id":"4914","checksum":"883eeccba8384ad7fcaa28761d99a0fa"}],"publication_status":"published","license":"https://creativecommons.org/licenses/by/4.0/","issue":"4","volume":19,"oa_version":"Published Version","abstract":[{"text":"The derivation of effective evolution equations is central to the study of non-stationary quantum many-body systems, and widely used in contexts such as superconductivity, nuclear physics, Bose–Einstein condensation and quantum chemistry. We reformulate the Dirac–Frenkel approximation principle in terms of reduced density matrices and apply it to fermionic and bosonic many-body systems. We obtain the Bogoliubov–de Gennes and Hartree–Fock–Bogoliubov equations, respectively. While we do not prove quantitative error estimates, our formulation does show that the approximation is optimal within the class of quasifree states. Furthermore, we prove well-posedness of the Bogoliubov–de Gennes equations in energy space and discuss conserved quantities","lang":"eng"}],"intvolume":" 19","month":"04","scopus_import":"1","alternative_title":["Annales Henri Poincare"],"ddc":["510","539"],"date_updated":"2023-09-19T10:07:41Z","file_date_updated":"2020-07-14T12:46:31Z","department":[{"_id":"RoSe"}],"_id":"455","pubrep_id":"993","status":"public","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"type":"journal_article","publication":"Annales Henri Poincare","day":"01","year":"2018","isi":1,"has_accepted_license":"1","date_created":"2018-12-11T11:46:34Z","doi":"10.1007/s00023-018-0644-z","date_published":"2018-04-01T00:00:00Z","page":"1167 - 1214","acknowledgement":"Open access funding provided by Institute of Science and Technology (IST Austria). The authors acknowledge support by ERC Advanced Grant 321029 and by VILLUM FONDEN via the QMATH Centre of Excellence (Grant No. 10059). The authors would like to thank Sébastien Breteaux, Enno Lenzmann, Mathieu Lewin and Jochen Schmid for comments and discussions about well-posedness of the Bogoliubov–de Gennes equations.","oa":1,"publisher":"Birkhäuser","quality_controlled":"1","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"ista":"Benedikter NP, Sok J, Solovej J. 2018. The Dirac–Frenkel principle for reduced density matrices and the Bogoliubov–de Gennes equations. Annales Henri Poincare. 19(4), 1167–1214.","chicago":"Benedikter, Niels P, Jérémy Sok, and Jan Solovej. “The Dirac–Frenkel Principle for Reduced Density Matrices and the Bogoliubov–de Gennes Equations.” Annales Henri Poincare. Birkhäuser, 2018. https://doi.org/10.1007/s00023-018-0644-z.","ama":"Benedikter NP, Sok J, Solovej J. The Dirac–Frenkel principle for reduced density matrices and the Bogoliubov–de Gennes equations. Annales Henri Poincare. 2018;19(4):1167-1214. doi:10.1007/s00023-018-0644-z","apa":"Benedikter, N. P., Sok, J., & Solovej, J. (2018). The Dirac–Frenkel principle for reduced density matrices and the Bogoliubov–de Gennes equations. Annales Henri Poincare. Birkhäuser. https://doi.org/10.1007/s00023-018-0644-z","short":"N.P. Benedikter, J. Sok, J. Solovej, Annales Henri Poincare 19 (2018) 1167–1214.","ieee":"N. P. Benedikter, J. Sok, and J. Solovej, “The Dirac–Frenkel principle for reduced density matrices and the Bogoliubov–de Gennes equations,” Annales Henri Poincare, vol. 19, no. 4. Birkhäuser, pp. 1167–1214, 2018.","mla":"Benedikter, Niels P., et al. “The Dirac–Frenkel Principle for Reduced Density Matrices and the Bogoliubov–de Gennes Equations.” Annales Henri Poincare, vol. 19, no. 4, Birkhäuser, 2018, pp. 1167–214, doi:10.1007/s00023-018-0644-z."},"title":"The Dirac–Frenkel principle for reduced density matrices and the Bogoliubov–de Gennes equations","external_id":{"isi":["000427578900006"]},"article_processing_charge":"No","author":[{"full_name":"Benedikter, Niels P","orcid":"0000-0002-1071-6091","last_name":"Benedikter","first_name":"Niels P","id":"3DE6C32A-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Jérémy","full_name":"Sok, Jérémy","last_name":"Sok"},{"first_name":"Jan","last_name":"Solovej","full_name":"Solovej, Jan"}],"publist_id":"7367"},{"abstract":[{"text":"The interface of physics and biology pro-vides a fruitful environment for generatingnew concepts and exciting ways forwardto understanding living matter. Examplesof successful studies include the estab-lishment and readout of morphogen gra-dients during development, signal pro-cessing in protein and genetic networks,the role of fluctuations in determining thefates of cells and tissues, and collectiveeffects in proteins and in tissues. It is nothard to envision that significant further ad-vances will translate to societal benefitsby initiating the development of new de-vices and strategies for curing disease.However, research at the interface posesvarious challenges, in particular for youngscientists, and current institutions arerarely designed to facilitate such scientificprograms. In this Letter, we propose aninternational initiative that addressesthese challenges through the establish-ment of a worldwide network of platformsfor cross-disciplinary training and incuba-tors for starting new collaborations.","lang":"eng"}],"oa_version":"Published Version","pmid":1,"main_file_link":[{"url":"https://doi.org/10.1016/j.cels.2018.04.003","open_access":"1"}],"scopus_import":"1","intvolume":" 6","month":"04","publication_status":"published","publication_identifier":{"eissn":["2405-4712"]},"language":[{"iso":"eng"}],"issue":"4","volume":6,"_id":"314","type":"journal_article","article_type":"letter_note","status":"public","date_updated":"2023-09-19T10:11:25Z","department":[{"_id":"AnKi"}],"oa":1,"quality_controlled":"1","publisher":"Cell Press","year":"2018","isi":1,"publication":"Cell Systems","day":"25","page":"400 - 402","date_created":"2018-12-11T11:45:46Z","date_published":"2018-04-25T00:00:00Z","doi":"10.1016/j.cels.2018.04.003","citation":{"chicago":"Bauer, Guntram, Nikta Fakhri, Anna Kicheva, Jané Kondev, Karsten Kruse, Hiroyuki Noji, Daniel Riveline, Timothy Saunders, Mukund Thatta, and Eric Wieschaus. “The Science of Living Matter for Tomorrow.” Cell Systems. Cell Press, 2018. https://doi.org/10.1016/j.cels.2018.04.003.","ista":"Bauer G, Fakhri N, Kicheva A, Kondev J, Kruse K, Noji H, Riveline D, Saunders T, Thatta M, Wieschaus E. 2018. The science of living matter for tomorrow. Cell Systems. 6(4), 400–402.","mla":"Bauer, Guntram, et al. “The Science of Living Matter for Tomorrow.” Cell Systems, vol. 6, no. 4, Cell Press, 2018, pp. 400–02, doi:10.1016/j.cels.2018.04.003.","ieee":"G. Bauer et al., “The science of living matter for tomorrow,” Cell Systems, vol. 6, no. 4. Cell Press, pp. 400–402, 2018.","short":"G. Bauer, N. Fakhri, A. Kicheva, J. Kondev, K. Kruse, H. Noji, D. Riveline, T. Saunders, M. Thatta, E. Wieschaus, Cell Systems 6 (2018) 400–402.","apa":"Bauer, G., Fakhri, N., Kicheva, A., Kondev, J., Kruse, K., Noji, H., … Wieschaus, E. (2018). The science of living matter for tomorrow. Cell Systems. Cell Press. https://doi.org/10.1016/j.cels.2018.04.003","ama":"Bauer G, Fakhri N, Kicheva A, et al. The science of living matter for tomorrow. Cell Systems. 2018;6(4):400-402. doi:10.1016/j.cels.2018.04.003"},"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","external_id":{"isi":["000432192100003"],"pmid":["29698645"]},"article_processing_charge":"No","author":[{"full_name":"Bauer, Guntram","last_name":"Bauer","first_name":"Guntram"},{"full_name":"Fakhri, Nikta","last_name":"Fakhri","first_name":"Nikta"},{"last_name":"Kicheva","full_name":"Kicheva, Anna","orcid":"0000-0003-4509-4998","id":"3959A2A0-F248-11E8-B48F-1D18A9856A87","first_name":"Anna"},{"last_name":"Kondev","full_name":"Kondev, Jané","first_name":"Jané"},{"last_name":"Kruse","full_name":"Kruse, Karsten","first_name":"Karsten"},{"first_name":"Hiroyuki","full_name":"Noji, Hiroyuki","last_name":"Noji"},{"first_name":"Daniel","last_name":"Riveline","full_name":"Riveline, Daniel"},{"full_name":"Saunders, Timothy","last_name":"Saunders","first_name":"Timothy"},{"full_name":"Thatta, Mukund","last_name":"Thatta","first_name":"Mukund"},{"full_name":"Wieschaus, Eric","last_name":"Wieschaus","first_name":"Eric"}],"publist_id":"7551","title":"The science of living matter for tomorrow"},{"issue":"1","volume":208,"language":[{"iso":"eng"}],"publication_status":"published","month":"01","intvolume":" 208","scopus_import":"1","main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753870/","open_access":"1"}],"oa_version":"Published Version","pmid":1,"abstract":[{"text":"We re-examine the model of Kirkpatrick and Barton for the spread of an inversion into a local population. This model assumes that local selection maintains alleles at two or more loci, despite immigration of alternative alleles at these loci from another population. We show that an inversion is favored because it prevents the breakdown of linkage disequilibrium generated by migration; the selective advantage of an inversion is proportional to the amount of recombination between the loci involved, as in other cases where inversions are selected for. We derive expressions for the rate of spread of an inversion; when the loci covered by the inversion are tightly linked, these conditions deviate substantially from those proposed previously, and imply that an inversion can then have only a small advantage. ","lang":"eng"}],"department":[{"_id":"NiBa"}],"date_updated":"2023-09-19T10:12:31Z","status":"public","article_type":"original","type":"journal_article","_id":"565","doi":"10.1534/genetics.117.300426","date_published":"2018-01-01T00:00:00Z","date_created":"2018-12-11T11:47:12Z","page":"377 - 382","day":"01","publication":"Genetics","isi":1,"year":"2018","quality_controlled":"1","publisher":"Genetics ","oa":1,"title":"The spread of an inversion with migration and selection","author":[{"first_name":"Brian","last_name":"Charlesworth","full_name":"Charlesworth, Brian"},{"last_name":"Barton","orcid":"0000-0002-8548-5240","full_name":"Barton, Nicholas H","first_name":"Nicholas H","id":"4880FE40-F248-11E8-B48F-1D18A9856A87"}],"publist_id":"7249","external_id":{"pmid":["29158424"],"isi":["000419356300025"]},"article_processing_charge":"No","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"mla":"Charlesworth, Brian, and Nicholas H. Barton. “The Spread of an Inversion with Migration and Selection.” Genetics, vol. 208, no. 1, Genetics , 2018, pp. 377–82, doi:10.1534/genetics.117.300426.","ieee":"B. Charlesworth and N. H. Barton, “The spread of an inversion with migration and selection,” Genetics, vol. 208, no. 1. Genetics , pp. 377–382, 2018.","short":"B. Charlesworth, N.H. Barton, Genetics 208 (2018) 377–382.","apa":"Charlesworth, B., & Barton, N. H. (2018). The spread of an inversion with migration and selection. Genetics. Genetics . https://doi.org/10.1534/genetics.117.300426","ama":"Charlesworth B, Barton NH. The spread of an inversion with migration and selection. Genetics. 2018;208(1):377-382. doi:10.1534/genetics.117.300426","chicago":"Charlesworth, Brian, and Nicholas H Barton. “The Spread of an Inversion with Migration and Selection.” Genetics. Genetics , 2018. https://doi.org/10.1534/genetics.117.300426.","ista":"Charlesworth B, Barton NH. 2018. The spread of an inversion with migration and selection. Genetics. 208(1), 377–382."}},{"status":"public","type":"journal_article","article_type":"original","_id":"446","department":[{"_id":"RoSe"}],"date_updated":"2023-09-19T10:09:40Z","intvolume":" 71","month":"03","main_file_link":[{"url":"https://arxiv.org/abs/1606.07355","open_access":"1"}],"oa_version":"Preprint","abstract":[{"lang":"eng","text":"We prove that in Thomas–Fermi–Dirac–von Weizsäcker theory, a nucleus of charge Z > 0 can bind at most Z + C electrons, where C is a universal constant. This result is obtained through a comparison with Thomas-Fermi theory which, as a by-product, gives bounds on the screened nuclear potential and the radius of the minimizer. A key ingredient of the proof is a novel technique to control the particles in the exterior region, which also applies to the liquid drop model with a nuclear background potential."}],"issue":"3","volume":71,"language":[{"iso":"eng"}],"publication_status":"published","title":"The ionization conjecture in Thomas–Fermi–Dirac–von Weizsäcker theory","article_processing_charge":"No","external_id":{"isi":["000422675800004"],"arxiv":["1606.07355"]},"author":[{"last_name":"Frank","full_name":"Frank, Rupert","first_name":"Rupert"},{"first_name":"Nam","id":"404092F4-F248-11E8-B48F-1D18A9856A87","last_name":"Phan Thanh","full_name":"Phan Thanh, Nam"},{"full_name":"Van Den Bosch, Hanne","last_name":"Van Den Bosch","first_name":"Hanne"}],"publist_id":"7377","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"chicago":"Frank, Rupert, Phan Nam, and Hanne Van Den Bosch. “The Ionization Conjecture in Thomas–Fermi–Dirac–von Weizsäcker Theory.” Communications on Pure and Applied Mathematics. Wiley-Blackwell, 2018. https://doi.org/10.1002/cpa.21717.","ista":"Frank R, Nam P, Van Den Bosch H. 2018. The ionization conjecture in Thomas–Fermi–Dirac–von Weizsäcker theory. Communications on Pure and Applied Mathematics. 71(3), 577–614.","mla":"Frank, Rupert, et al. “The Ionization Conjecture in Thomas–Fermi–Dirac–von Weizsäcker Theory.” Communications on Pure and Applied Mathematics, vol. 71, no. 3, Wiley-Blackwell, 2018, pp. 577–614, doi:10.1002/cpa.21717.","short":"R. Frank, P. Nam, H. Van Den Bosch, Communications on Pure and Applied Mathematics 71 (2018) 577–614.","ieee":"R. Frank, P. Nam, and H. Van Den Bosch, “The ionization conjecture in Thomas–Fermi–Dirac–von Weizsäcker theory,” Communications on Pure and Applied Mathematics, vol. 71, no. 3. Wiley-Blackwell, pp. 577–614, 2018.","apa":"Frank, R., Nam, P., & Van Den Bosch, H. (2018). The ionization conjecture in Thomas–Fermi–Dirac–von Weizsäcker theory. Communications on Pure and Applied Mathematics. Wiley-Blackwell. https://doi.org/10.1002/cpa.21717","ama":"Frank R, Nam P, Van Den Bosch H. The ionization conjecture in Thomas–Fermi–Dirac–von Weizsäcker theory. Communications on Pure and Applied Mathematics. 2018;71(3):577-614. doi:10.1002/cpa.21717"},"oa":1,"publisher":"Wiley-Blackwell","quality_controlled":"1","acknowledgement":"We thank the referee for helpful suggestions that improved the presentation of the paper. We also acknowledge partial support by National Science Foundation Grant DMS-1363432 (R.L.F.), Austrian Science Fund (FWF) Project Nr. P 27533-N27 (P.T.N.), CONICYT (Chile) through CONICYT–PCHA/ Doctorado Nacional/2014, and Iniciativa Científica Milenio (Chile) through Millenium Nucleus RC–120002 “Física Matemática” (H.V.D.B.).\r\n","date_created":"2018-12-11T11:46:31Z","doi":"10.1002/cpa.21717","date_published":"2018-03-01T00:00:00Z","page":"577 - 614","publication":"Communications on Pure and Applied Mathematics","day":"01","year":"2018","isi":1},{"ddc":["576"],"date_updated":"2023-09-19T10:17:30Z","file_date_updated":"2020-07-14T12:46:26Z","department":[{"_id":"NiBa"}],"_id":"430","pubrep_id":"1012","status":"public","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"type":"journal_article","language":[{"iso":"eng"}],"file":[{"checksum":"3d838dc285df394376555b794b6a5ad1","file_id":"4958","content_type":"application/pdf","access_level":"open_access","relation":"main_file","date_created":"2018-12-12T10:12:40Z","file_name":"IST-2018-1012-v1+1_2018_Barton_Tread.pdf","date_updated":"2020-07-14T12:46:26Z","file_size":500129,"creator":"system"}],"publication_status":"published","volume":208,"issue":"4","oa_version":"Published Version","abstract":[{"text":"In this issue of GENETICS, a new method for detecting natural selection on polygenic traits is developed and applied to sev- eral human examples ( Racimo et al. 2018 ). By de fi nition, many loci contribute to variation in polygenic traits, and a challenge for evolutionary ge neticists has been that these traits can evolve by small, nearly undetectable shifts in allele frequencies across each of many, typically unknown, loci. Recently, a helpful remedy has arisen. Genome-wide associ- ation studies (GWAS) have been illuminating sets of loci that can be interrogated jointly for c hanges in allele frequencies. By aggregating small signal s of change across many such loci, directional natural selection is now in principle detect- able using genetic data, even for highly polygenic traits. This is an exciting arena of progress – with these methods, tests can be made for selection associated with traits, and we can now study selection in what may be its most prevalent mode. The continuing fast pace of GWAS publications suggest there will be many more polygenic tests of selection in the near future, as every new GWAS is an opportunity for an accom- panying test of polygenic selection. However, it is important to be aware of complications th at arise in interpretation, especially given that these studies may easily be misinter- preted both in and outside the evolutionary genetics commu- nity. Here, we provide context for understanding polygenic tests and urge caution regarding how these results are inter- preted and reported upon more broadly.","lang":"eng"}],"intvolume":" 208","month":"04","scopus_import":"1","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"ista":"Novembre J, Barton NH. 2018. Tread lightly interpreting polygenic tests of selection. Genetics. 208(4), 1351–1355.","chicago":"Novembre, John, and Nicholas H Barton. “Tread Lightly Interpreting Polygenic Tests of Selection.” Genetics. Genetics Society of America, 2018. https://doi.org/10.1534/genetics.118.300786.","apa":"Novembre, J., & Barton, N. H. (2018). Tread lightly interpreting polygenic tests of selection. Genetics. Genetics Society of America. https://doi.org/10.1534/genetics.118.300786","ama":"Novembre J, Barton NH. Tread lightly interpreting polygenic tests of selection. Genetics. 2018;208(4):1351-1355. doi:10.1534/genetics.118.300786","ieee":"J. Novembre and N. H. Barton, “Tread lightly interpreting polygenic tests of selection,” Genetics, vol. 208, no. 4. Genetics Society of America, pp. 1351–1355, 2018.","short":"J. Novembre, N.H. Barton, Genetics 208 (2018) 1351–1355.","mla":"Novembre, John, and Nicholas H. Barton. “Tread Lightly Interpreting Polygenic Tests of Selection.” Genetics, vol. 208, no. 4, Genetics Society of America, 2018, pp. 1351–55, doi:10.1534/genetics.118.300786."},"title":"Tread lightly interpreting polygenic tests of selection","external_id":{"isi":["000429094400005"]},"article_processing_charge":"No","publist_id":"7393","author":[{"first_name":"John","full_name":"Novembre, John","last_name":"Novembre"},{"id":"4880FE40-F248-11E8-B48F-1D18A9856A87","first_name":"Nicholas H","last_name":"Barton","full_name":"Barton, Nicholas H","orcid":"0000-0002-8548-5240"}],"publication":"Genetics","day":"01","year":"2018","isi":1,"has_accepted_license":"1","date_created":"2018-12-11T11:46:26Z","date_published":"2018-04-01T00:00:00Z","doi":"10.1534/genetics.118.300786","page":"1351 - 1355","oa":1,"publisher":"Genetics Society of America","quality_controlled":"1"},{"oa":1,"quality_controlled":"1","publisher":"MDPI AG","publication":"Genes","day":"12","year":"2018","isi":1,"has_accepted_license":"1","date_created":"2018-12-11T11:45:09Z","doi":"10.3390/genes9060294","date_published":"2018-06-12T00:00:00Z","article_number":"294","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"ista":"Ma W, Veltsos P, Toups MA, Rodrigues N, Sermier R, Jeffries D, Perrin N. 2018. Tissue specificity and dynamics of sex biased gene expression in a common frog population with differentiated, yet homomorphic, sex chromosomes. Genes. 9(6), 294.","chicago":"Ma, Wen, Paris Veltsos, Melissa A Toups, Nicolas Rodrigues, Roberto Sermier, Daniel Jeffries, and Nicolas Perrin. “Tissue Specificity and Dynamics of Sex Biased Gene Expression in a Common Frog Population with Differentiated, yet Homomorphic, Sex Chromosomes.” Genes. MDPI AG, 2018. https://doi.org/10.3390/genes9060294.","ieee":"W. Ma et al., “Tissue specificity and dynamics of sex biased gene expression in a common frog population with differentiated, yet homomorphic, sex chromosomes,” Genes, vol. 9, no. 6. MDPI AG, 2018.","short":"W. Ma, P. Veltsos, M.A. Toups, N. Rodrigues, R. Sermier, D. Jeffries, N. Perrin, Genes 9 (2018).","apa":"Ma, W., Veltsos, P., Toups, M. A., Rodrigues, N., Sermier, R., Jeffries, D., & Perrin, N. (2018). Tissue specificity and dynamics of sex biased gene expression in a common frog population with differentiated, yet homomorphic, sex chromosomes. Genes. MDPI AG. https://doi.org/10.3390/genes9060294","ama":"Ma W, Veltsos P, Toups MA, et al. Tissue specificity and dynamics of sex biased gene expression in a common frog population with differentiated, yet homomorphic, sex chromosomes. Genes. 2018;9(6). doi:10.3390/genes9060294","mla":"Ma, Wen, et al. “Tissue Specificity and Dynamics of Sex Biased Gene Expression in a Common Frog Population with Differentiated, yet Homomorphic, Sex Chromosomes.” Genes, vol. 9, no. 6, 294, MDPI AG, 2018, doi:10.3390/genes9060294."},"title":"Tissue specificity and dynamics of sex biased gene expression in a common frog population with differentiated, yet homomorphic, sex chromosomes","article_processing_charge":"No","external_id":{"isi":["000436494200026"]},"publist_id":"7714","author":[{"first_name":"Wen","last_name":"Ma","full_name":"Ma, Wen"},{"first_name":"Paris","last_name":"Veltsos","full_name":"Veltsos, Paris"},{"id":"4E099E4E-F248-11E8-B48F-1D18A9856A87","first_name":"Melissa A","last_name":"Toups","orcid":"0000-0002-9752-7380","full_name":"Toups, Melissa A"},{"full_name":"Rodrigues, Nicolas","last_name":"Rodrigues","first_name":"Nicolas"},{"last_name":"Sermier","full_name":"Sermier, Roberto","first_name":"Roberto"},{"first_name":"Daniel","full_name":"Jeffries, Daniel","last_name":"Jeffries"},{"full_name":"Perrin, Nicolas","last_name":"Perrin","first_name":"Nicolas"}],"oa_version":"Published Version","abstract":[{"text":"Sex-biased genes are central to the study of sexual selection, sexual antagonism, and sex chromosome evolution. We describe a comprehensive de novo assembled transcriptome in the common frog Rana temporaria based on five developmental stages and three adult tissues from both sexes, obtained from a population with karyotypically homomorphic but genetically differentiated sex chromosomes. This allows the study of sex-biased gene expression throughout development, and its effect on the rate of gene evolution while accounting for pleiotropic expression, which is known to negatively correlate with the evolutionary rate. Overall, sex-biased genes had little overlap among developmental stages and adult tissues. Late developmental stages and gonad tissues had the highest numbers of stage-or tissue-specific genes. We find that pleiotropic gene expression is a better predictor than sex bias for the evolutionary rate of genes, though it often interacts with sex bias. Although genetically differentiated, the sex chromosomes were not enriched in sex-biased genes, possibly due to a very recent arrest of XY recombination. These results extend our understanding of the developmental dynamics, tissue specificity, and genomic localization of sex-biased genes.","lang":"eng"}],"intvolume":" 9","month":"06","scopus_import":"1","language":[{"iso":"eng"}],"file":[{"relation":"main_file","access_level":"open_access","content_type":"application/pdf","checksum":"423069beb1cd3cdd25bf3f464b38f1d7","file_id":"5905","creator":"dernst","file_size":3985796,"date_updated":"2020-07-14T12:45:22Z","file_name":"2018_Genes_Ma.pdf","date_created":"2019-02-01T07:52:28Z"}],"publication_status":"published","issue":"6","volume":9,"_id":"199","status":"public","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"type":"journal_article","ddc":["570"],"date_updated":"2023-09-19T10:15:31Z","department":[{"_id":"BeVi"}],"file_date_updated":"2020-07-14T12:45:22Z"},{"project":[{"name":"Sensitivity to higher-order statistics in natural scenes","grant_number":"P 25651-N26","call_identifier":"FWF","_id":"254D1A94-B435-11E9-9278-68D0E5697425"}],"title":"Toward a unified theory of efficient, predictive, and sparse coding","publist_id":"7273","author":[{"first_name":"Matthew J","id":"2BAAC544-F248-11E8-B48F-1D18A9856A87","full_name":"Chalk, Matthew J","orcid":"0000-0001-7782-4436","last_name":"Chalk"},{"first_name":"Olivier","last_name":"Marre","full_name":"Marre, Olivier"},{"last_name":"Tkacik","full_name":"Tkacik, Gasper","orcid":"0000-0002-6699-1455","id":"3D494DCA-F248-11E8-B48F-1D18A9856A87","first_name":"Gasper"}],"external_id":{"isi":["000419128700049"]},"article_processing_charge":"No","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"chicago":"Chalk, Matthew J, Olivier Marre, and Gašper Tkačik. “Toward a Unified Theory of Efficient, Predictive, and Sparse Coding.” PNAS. National Academy of Sciences, 2018. https://doi.org/10.1073/pnas.1711114115.","ista":"Chalk MJ, Marre O, Tkačik G. 2018. Toward a unified theory of efficient, predictive, and sparse coding. PNAS. 115(1), 186–191.","mla":"Chalk, Matthew J., et al. “Toward a Unified Theory of Efficient, Predictive, and Sparse Coding.” PNAS, vol. 115, no. 1, National Academy of Sciences, 2018, pp. 186–91, doi:10.1073/pnas.1711114115.","ama":"Chalk MJ, Marre O, Tkačik G. Toward a unified theory of efficient, predictive, and sparse coding. PNAS. 2018;115(1):186-191. doi:10.1073/pnas.1711114115","apa":"Chalk, M. J., Marre, O., & Tkačik, G. (2018). Toward a unified theory of efficient, predictive, and sparse coding. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.1711114115","short":"M.J. Chalk, O. Marre, G. Tkačik, PNAS 115 (2018) 186–191.","ieee":"M. J. Chalk, O. Marre, and G. Tkačik, “Toward a unified theory of efficient, predictive, and sparse coding,” PNAS, vol. 115, no. 1. National Academy of Sciences, pp. 186–191, 2018."},"quality_controlled":"1","publisher":"National Academy of Sciences","oa":1,"doi":"10.1073/pnas.1711114115","date_published":"2018-01-02T00:00:00Z","date_created":"2018-12-11T11:47:04Z","page":"186 - 191","day":"02","publication":"PNAS","isi":1,"year":"2018","status":"public","type":"journal_article","_id":"543","department":[{"_id":"GaTk"}],"date_updated":"2023-09-19T10:16:35Z","month":"01","intvolume":" 115","scopus_import":"1","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/152660 "}],"oa_version":"Submitted Version","abstract":[{"text":"A central goal in theoretical neuroscience is to predict the response properties of sensory neurons from first principles. To this end, “efficient coding” posits that sensory neurons encode maximal information about their inputs given internal constraints. There exist, however, many variants of efficient coding (e.g., redundancy reduction, different formulations of predictive coding, robust coding, sparse coding, etc.), differing in their regimes of applicability, in the relevance of signals to be encoded, and in the choice of constraints. It is unclear how these types of efficient coding relate or what is expected when different coding objectives are combined. Here we present a unified framework that encompasses previously proposed efficient coding models and extends to unique regimes. We show that optimizing neural responses to encode predictive information can lead them to either correlate or decorrelate their inputs, depending on the stimulus statistics; in contrast, at low noise, efficiently encoding the past always predicts decorrelation. Later, we investigate coding of naturalistic movies and show that qualitatively different types of visual motion tuning and levels of response sparsity are predicted, depending on whether the objective is to recover the past or predict the future. Our approach promises a way to explain the observed diversity of sensory neural responses, as due to multiple functional goals and constraints fulfilled by different cell types and/or circuits.","lang":"eng"}],"issue":"1","volume":115,"language":[{"iso":"eng"}],"publication_status":"published"},{"title":"Theory of eppithelial cell shape transitions induced by mechanoactive chemical gradients","author":[{"first_name":"Kinjal","full_name":"Dasbiswas, Kinjal","last_name":"Dasbiswas"},{"first_name":"Claude-Edouard B","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","full_name":"Hannezo, Claude-Edouard B","orcid":"0000-0001-6005-1561","last_name":"Hannezo"},{"first_name":"Nir","full_name":"Gov, Nir","last_name":"Gov"}],"publist_id":"7403","external_id":{"arxiv":["1709.01486"],"isi":["000428016700021"]},"article_processing_charge":"No","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"mla":"Dasbiswas, Kinjal, et al. “Theory of Eppithelial Cell Shape Transitions Induced by Mechanoactive Chemical Gradients.” Biophysical Journal, vol. 114, no. 4, Biophysical Society, 2018, pp. 968–77, doi:10.1016/j.bpj.2017.12.022.","short":"K. Dasbiswas, E.B. Hannezo, N. Gov, Biophysical Journal 114 (2018) 968–977.","ieee":"K. Dasbiswas, E. B. Hannezo, and N. Gov, “Theory of eppithelial cell shape transitions induced by mechanoactive chemical gradients,” Biophysical Journal, vol. 114, no. 4. Biophysical Society, pp. 968–977, 2018.","ama":"Dasbiswas K, Hannezo EB, Gov N. Theory of eppithelial cell shape transitions induced by mechanoactive chemical gradients. Biophysical Journal. 2018;114(4):968-977. doi:10.1016/j.bpj.2017.12.022","apa":"Dasbiswas, K., Hannezo, E. B., & Gov, N. (2018). Theory of eppithelial cell shape transitions induced by mechanoactive chemical gradients. Biophysical Journal. Biophysical Society. https://doi.org/10.1016/j.bpj.2017.12.022","chicago":"Dasbiswas, Kinjal, Edouard B Hannezo, and Nir Gov. “Theory of Eppithelial Cell Shape Transitions Induced by Mechanoactive Chemical Gradients.” Biophysical Journal. Biophysical Society, 2018. https://doi.org/10.1016/j.bpj.2017.12.022.","ista":"Dasbiswas K, Hannezo EB, Gov N. 2018. Theory of eppithelial cell shape transitions induced by mechanoactive chemical gradients. Biophysical Journal. 114(4), 968–977."},"doi":"10.1016/j.bpj.2017.12.022","date_published":"2018-02-27T00:00:00Z","date_created":"2018-12-11T11:46:23Z","page":"968 - 977","day":"27","publication":"Biophysical Journal","isi":1,"year":"2018","publisher":"Biophysical Society","quality_controlled":"1","oa":1,"department":[{"_id":"EdHa"}],"date_updated":"2023-09-19T10:13:55Z","status":"public","type":"journal_article","_id":"421","issue":"4","volume":114,"language":[{"iso":"eng"}],"publication_status":"published","month":"02","intvolume":" 114","scopus_import":"1","main_file_link":[{"url":"https://arxiv.org/abs/1709.01486","open_access":"1"}],"oa_version":"Submitted Version","abstract":[{"lang":"eng","text":"Cell shape is determined by a balance of intrinsic properties of the cell as well as its mechanochemical environment. Inhomogeneous shape changes underlie many morphogenetic events and involve spatial gradients in active cellular forces induced by complex chemical signaling. Here, we introduce a mechanochemical model based on the notion that cell shape changes may be induced by external diffusible biomolecules that influence cellular contractility (or equivalently, adhesions) in a concentration-dependent manner—and whose spatial profile in turn is affected by cell shape. We map out theoretically the possible interplay between chemical concentration and cellular structure. Besides providing a direct route to spatial gradients in cell shape profiles in tissues, we show that the dependence on cell shape helps create robust mechanochemical gradients."}]}]