@article{12186, abstract = {Activation of cell-surface and intracellular receptor-mediated immunity results in rapid transcriptional reprogramming that underpins disease resistance. However, the mechanisms by which co-activation of both immune systems lead to transcriptional changes are not clear. Here, we combine RNA-seq and ATAC-seq to define changes in gene expression and chromatin accessibility. Activation of cell-surface or intracellular receptor-mediated immunity, or both, increases chromatin accessibility at induced defence genes. Analysis of ATAC-seq and RNA-seq data combined with publicly available information on transcription factor DNA-binding motifs enabled comparison of individual gene regulatory networks activated by cell-surface or intracellular receptor-mediated immunity, or by both. These results and analyses reveal overlapping and conserved transcriptional regulatory mechanisms between the two immune systems.}, author = {Ding, Pingtao and Sakai, Toshiyuki and Krishna Shrestha, Ram and Manosalva Perez, Nicolas and Guo, Wenbin and Ngou, Bruno Pok Man and He, Shengbo and Liu, Chang and Feng, Xiaoqi and Zhang, Runxuan and Vandepoele, Klaas and MacLean, Dan and Jones, Jonathan D G}, issn = {0022-0957}, journal = {Journal of Experimental Botany}, keywords = {Plant Science, Physiology}, number = {22}, pages = {7927--7941}, publisher = {Oxford University Press}, title = {{Chromatin accessibility landscapes activated by cell-surface and intracellular immune receptors}}, doi = {10.1093/jxb/erab373}, volume = {72}, year = {2021}, }