--- _id: '15166' abstract: - lang: eng text: Reducing defects boosts room-temperature performance of a thermoelectric device acknowledgement: The authors thank the Werner-Siemens-Stiftung and the Institute of Science and Technology Austria for financial support. article_processing_charge: No article_type: letter_note author: - first_name: Navita full_name: Navita, Navita id: 6ebe278d-ba0b-11ee-8184-f34cdc671de4 last_name: Navita - first_name: Maria full_name: Ibáñez, Maria id: 43C61214-F248-11E8-B48F-1D18A9856A87 last_name: Ibáñez orcid: 0000-0001-5013-2843 citation: ama: Jakhar N, Ibáñez M. Electron highways are cooler. Science. 2024;383(6688):1184. doi:10.1126/science.ado4077 apa: Jakhar, N., & Ibáñez, M. (2024). Electron highways are cooler. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.ado4077 chicago: Jakhar, Navita, and Maria Ibáñez. “Electron Highways Are Cooler.” Science. American Association for the Advancement of Science, 2024. https://doi.org/10.1126/science.ado4077. ieee: N. Jakhar and M. Ibáñez, “Electron highways are cooler,” Science, vol. 383, no. 6688. American Association for the Advancement of Science, p. 1184, 2024. ista: Jakhar N, Ibáñez M. 2024. Electron highways are cooler. Science. 383(6688), 1184. mla: Jakhar, Navita, and Maria Ibáñez. “Electron Highways Are Cooler.” Science, vol. 383, no. 6688, American Association for the Advancement of Science, 2024, p. 1184, doi:10.1126/science.ado4077. short: N. Jakhar, M. Ibáñez, Science 383 (2024) 1184. date_created: 2024-03-24T23:00:58Z date_published: 2024-03-14T00:00:00Z date_updated: 2024-03-25T10:31:20Z day: '14' department: - _id: MaIb doi: 10.1126/science.ado4077 intvolume: ' 383' issue: '6688' language: - iso: eng month: '03' oa_version: None page: '1184' project: - _id: 9B8F7476-BA93-11EA-9121-9846C619BF3A name: 'HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery' publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Electron highways are cooler type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 383 year: '2024' ... --- _id: '13106' abstract: - lang: eng text: Quantum entanglement is a key resource in currently developed quantum technologies. Sharing this fragile property between superconducting microwave circuits and optical or atomic systems would enable new functionalities, but this has been hindered by an energy scale mismatch of >104 and the resulting mutually imposed loss and noise. In this work, we created and verified entanglement between microwave and optical fields in a millikelvin environment. Using an optically pulsed superconducting electro-optical device, we show entanglement between propagating microwave and optical fields in the continuous variable domain. This achievement not only paves the way for entanglement between superconducting circuits and telecom wavelength light, but also has wide-ranging implications for hybrid quantum networks in the context of modularization, scaling, sensing, and cross-platform verification. acknowledgement: This work was supported by the European Research Council (grant no. 758053, ERC StG QUNNECT) and the European Union’s Horizon 2020 Research and Innovation Program (grant no. 899354, FETopen SuperQuLAN). L.Q. acknowledges generous support from the ISTFELLOW program. W.H. is the recipient of an ISTplus postdoctoral fellowship with funding from the European Union’s Horizon 2020 Research and Innovation Program (Marie Sklodowska-Curie grant no. 754411). G.A. is the recipient of a DOC fellowship of the Austrian Academy of Sciences at IST Austria. J.M.F. acknowledges support from the Austrian Science Fund (FWF) through BeyondC (grant no. F7105) and the European Union’s Horizon 2020 Research and Innovation Program (grant no. 862644, FETopen QUARTET). article_processing_charge: No article_type: original author: - first_name: Rishabh full_name: Sahu, Rishabh id: 47D26E34-F248-11E8-B48F-1D18A9856A87 last_name: Sahu orcid: 0000-0001-6264-2162 - first_name: Liu full_name: Qiu, Liu id: 45e99c0d-1eb1-11eb-9b96-ed8ab2983cac last_name: Qiu orcid: 0000-0003-4345-4267 - first_name: William J full_name: Hease, William J id: 29705398-F248-11E8-B48F-1D18A9856A87 last_name: Hease - first_name: Georg M full_name: Arnold, Georg M id: 3770C838-F248-11E8-B48F-1D18A9856A87 last_name: Arnold - first_name: Y. full_name: Minoguchi, Y. last_name: Minoguchi - first_name: P. full_name: Rabl, P. last_name: Rabl - first_name: Johannes M full_name: Fink, Johannes M id: 4B591CBA-F248-11E8-B48F-1D18A9856A87 last_name: Fink orcid: 0000-0001-8112-028X citation: ama: Sahu R, Qiu L, Hease WJ, et al. Entangling microwaves with light. Science. 2023;380(6646):718-721. doi:10.1126/science.adg3812 apa: Sahu, R., Qiu, L., Hease, W. J., Arnold, G. M., Minoguchi, Y., Rabl, P., & Fink, J. M. (2023). Entangling microwaves with light. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.adg3812 chicago: Sahu, Rishabh, Liu Qiu, William J Hease, Georg M Arnold, Y. Minoguchi, P. Rabl, and Johannes M Fink. “Entangling Microwaves with Light.” Science. American Association for the Advancement of Science, 2023. https://doi.org/10.1126/science.adg3812. ieee: R. Sahu et al., “Entangling microwaves with light,” Science, vol. 380, no. 6646. American Association for the Advancement of Science, pp. 718–721, 2023. ista: Sahu R, Qiu L, Hease WJ, Arnold GM, Minoguchi Y, Rabl P, Fink JM. 2023. Entangling microwaves with light. Science. 380(6646), 718–721. mla: Sahu, Rishabh, et al. “Entangling Microwaves with Light.” Science, vol. 380, no. 6646, American Association for the Advancement of Science, 2023, pp. 718–21, doi:10.1126/science.adg3812. short: R. Sahu, L. Qiu, W.J. Hease, G.M. Arnold, Y. Minoguchi, P. Rabl, J.M. Fink, Science 380 (2023) 718–721. date_created: 2023-05-31T11:39:24Z date_published: 2023-05-18T00:00:00Z date_updated: 2023-08-02T06:08:57Z day: '18' department: - _id: JoFi doi: 10.1126/science.adg3812 ec_funded: 1 external_id: arxiv: - '2301.03315' isi: - '000996515200004' intvolume: ' 380' isi: 1 issue: '6646' keyword: - Multidisciplinary language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.48550/arXiv.2301.03315 month: '05' oa: 1 oa_version: Preprint page: 718-721 project: - _id: 26336814-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '758053' name: A Fiber Optic Transceiver for Superconducting Qubits - _id: 9B868D20-BA93-11EA-9121-9846C619BF3A call_identifier: H2020 grant_number: '899354' name: Quantum Local Area Networks with Superconducting Qubits - _id: 260C2330-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '754411' name: ISTplus - Postdoctoral Fellowships - _id: 26927A52-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: F07105 name: Integrating superconducting quantum circuits - _id: 237CBA6C-32DE-11EA-91FC-C7463DDC885E call_identifier: H2020 grant_number: '862644' name: Quantum readout techniques and technologies - _id: 2671EB66-B435-11E9-9278-68D0E5697425 name: Coherent on-chip conversion of superconducting qubit signals from microwaves to optical frequencies publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' related_material: link: - description: News on ISTA Website relation: press_release url: https://ista.ac.at/en/news/wiring-up-quantum-circuits-with-light/ record: - id: '13122' relation: research_data status: public status: public title: Entangling microwaves with light type: journal_article user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8 volume: 380 year: '2023' ... --- _id: '14281' abstract: - lang: eng text: In nature, proteins that switch between two conformations in response to environmental stimuli structurally transduce biochemical information in a manner analogous to how transistors control information flow in computing devices. Designing proteins with two distinct but fully structured conformations is a challenge for protein design as it requires sculpting an energy landscape with two distinct minima. Here we describe the design of “hinge” proteins that populate one designed state in the absence of ligand and a second designed state in the presence of ligand. X-ray crystallography, electron microscopy, double electron-electron resonance spectroscopy, and binding measurements demonstrate that despite the significant structural differences the two states are designed with atomic level accuracy and that the conformational and binding equilibria are closely coupled. article_processing_charge: No article_type: original author: - first_name: Florian M full_name: Praetorius, Florian M id: dfec9381-4341-11ee-8fd8-faa02bba7d62 last_name: Praetorius - first_name: Philip J. Y. full_name: Leung, Philip J. Y. last_name: Leung - first_name: Maxx H. full_name: Tessmer, Maxx H. last_name: Tessmer - first_name: Adam full_name: Broerman, Adam last_name: Broerman - first_name: Cullen full_name: Demakis, Cullen last_name: Demakis - first_name: Acacia F. full_name: Dishman, Acacia F. last_name: Dishman - first_name: Arvind full_name: Pillai, Arvind last_name: Pillai - first_name: Abbas full_name: Idris, Abbas last_name: Idris - first_name: David full_name: Juergens, David last_name: Juergens - first_name: Justas full_name: Dauparas, Justas last_name: Dauparas - first_name: Xinting full_name: Li, Xinting last_name: Li - first_name: Paul M. full_name: Levine, Paul M. last_name: Levine - first_name: Mila full_name: Lamb, Mila last_name: Lamb - first_name: Ryanne K. full_name: Ballard, Ryanne K. last_name: Ballard - first_name: Stacey R. full_name: Gerben, Stacey R. last_name: Gerben - first_name: Hannah full_name: Nguyen, Hannah last_name: Nguyen - first_name: Alex full_name: Kang, Alex last_name: Kang - first_name: Banumathi full_name: Sankaran, Banumathi last_name: Sankaran - first_name: Asim K. full_name: Bera, Asim K. last_name: Bera - first_name: Brian F. full_name: Volkman, Brian F. last_name: Volkman - first_name: Jeff full_name: Nivala, Jeff last_name: Nivala - first_name: Stefan full_name: Stoll, Stefan last_name: Stoll - first_name: David full_name: Baker, David last_name: Baker citation: ama: Praetorius FM, Leung PJY, Tessmer MH, et al. Design of stimulus-responsive two-state hinge proteins. Science. 2023;381(6659):754-760. doi:10.1126/science.adg7731 apa: Praetorius, F. M., Leung, P. J. Y., Tessmer, M. H., Broerman, A., Demakis, C., Dishman, A. F., … Baker, D. (2023). Design of stimulus-responsive two-state hinge proteins. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.adg7731 chicago: Praetorius, Florian M, Philip J. Y. Leung, Maxx H. Tessmer, Adam Broerman, Cullen Demakis, Acacia F. Dishman, Arvind Pillai, et al. “Design of Stimulus-Responsive Two-State Hinge Proteins.” Science. American Association for the Advancement of Science, 2023. https://doi.org/10.1126/science.adg7731. ieee: F. M. Praetorius et al., “Design of stimulus-responsive two-state hinge proteins,” Science, vol. 381, no. 6659. American Association for the Advancement of Science, pp. 754–760, 2023. ista: Praetorius FM, Leung PJY, Tessmer MH, Broerman A, Demakis C, Dishman AF, Pillai A, Idris A, Juergens D, Dauparas J, Li X, Levine PM, Lamb M, Ballard RK, Gerben SR, Nguyen H, Kang A, Sankaran B, Bera AK, Volkman BF, Nivala J, Stoll S, Baker D. 2023. Design of stimulus-responsive two-state hinge proteins. Science. 381(6659), 754–760. mla: Praetorius, Florian M., et al. “Design of Stimulus-Responsive Two-State Hinge Proteins.” Science, vol. 381, no. 6659, American Association for the Advancement of Science, 2023, pp. 754–60, doi:10.1126/science.adg7731. short: F.M. Praetorius, P.J.Y. Leung, M.H. Tessmer, A. Broerman, C. Demakis, A.F. Dishman, A. Pillai, A. Idris, D. Juergens, J. Dauparas, X. Li, P.M. Levine, M. Lamb, R.K. Ballard, S.R. Gerben, H. Nguyen, A. Kang, B. Sankaran, A.K. Bera, B.F. Volkman, J. Nivala, S. Stoll, D. Baker, Science 381 (2023) 754–760. date_created: 2023-09-06T12:04:23Z date_published: 2023-08-17T00:00:00Z date_updated: 2023-11-07T12:42:09Z day: '17' doi: 10.1126/science.adg7731 extern: '1' external_id: pmid: - '37590357' intvolume: ' 381' issue: '6659' language: - iso: eng month: '08' oa_version: None page: 754-760 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Design of stimulus-responsive two-state hinge proteins type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 381 year: '2023' ... --- _id: '15085' abstract: - lang: eng text: The hydrogen-rich outer layers of massive stars can be removed by interactions with a binary companion. Theoretical models predict that this stripping produces a population of hot helium stars of ~2 to 8 solar masses (M☉), however, only one such system has been identified thus far. We used ultraviolet photometry to identify potential stripped helium stars then investigated 25 of them using optical spectroscopy. We identified stars with high temperatures (~60,000 to 100,000 kelvin), high surface gravities, and hydrogen-depleted surfaces; 16 stars also showed binary motion. These properties match expectations for stars with initial masses of 8 to 25 M☉ that were stripped by binary interaction. Their masses fall in the gap between subdwarf helium stars and Wolf-Rayet stars. We propose that these stars could be progenitors of stripped-envelope supernovae. article_processing_charge: No article_type: original author: - first_name: M. R. full_name: Drout, M. R. last_name: Drout - first_name: Ylva Louise Linsdotter full_name: Götberg, Ylva Louise Linsdotter id: d0648d0c-0f64-11ee-a2e0-dd0faa2e4f7d last_name: Götberg orcid: 0000-0002-6960-6911 - first_name: B. A. full_name: Ludwig, B. A. last_name: Ludwig - first_name: J. H. full_name: Groh, J. H. last_name: Groh - first_name: S. E. full_name: de Mink, S. E. last_name: de Mink - first_name: A. J. G. full_name: O’Grady, A. J. G. last_name: O’Grady - first_name: N. full_name: Smith, N. last_name: Smith citation: ama: Drout MR, Götberg YLL, Ludwig BA, et al. An observed population of intermediate-mass helium stars that have been stripped in binaries. Science. 2023;382(6676):1287-1291. doi:10.1126/science.ade4970 apa: Drout, M. R., Götberg, Y. L. L., Ludwig, B. A., Groh, J. H., de Mink, S. E., O’Grady, A. J. G., & Smith, N. (2023). An observed population of intermediate-mass helium stars that have been stripped in binaries. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.ade4970 chicago: Drout, M. R., Ylva Louise Linsdotter Götberg, B. A. Ludwig, J. H. Groh, S. E. de Mink, A. J. G. O’Grady, and N. Smith. “An Observed Population of Intermediate-Mass Helium Stars That Have Been Stripped in Binaries.” Science. American Association for the Advancement of Science, 2023. https://doi.org/10.1126/science.ade4970. ieee: M. R. Drout et al., “An observed population of intermediate-mass helium stars that have been stripped in binaries,” Science, vol. 382, no. 6676. American Association for the Advancement of Science, pp. 1287–1291, 2023. ista: Drout MR, Götberg YLL, Ludwig BA, Groh JH, de Mink SE, O’Grady AJG, Smith N. 2023. An observed population of intermediate-mass helium stars that have been stripped in binaries. Science. 382(6676), 1287–1291. mla: Drout, M. R., et al. “An Observed Population of Intermediate-Mass Helium Stars That Have Been Stripped in Binaries.” Science, vol. 382, no. 6676, American Association for the Advancement of Science, 2023, pp. 1287–91, doi:10.1126/science.ade4970. short: M.R. Drout, Y.L.L. Götberg, B.A. Ludwig, J.H. Groh, S.E. de Mink, A.J.G. O’Grady, N. Smith, Science 382 (2023) 1287–1291. date_created: 2024-03-05T09:40:28Z date_published: 2023-12-14T00:00:00Z date_updated: 2024-03-13T07:40:04Z day: '14' doi: 10.1126/science.ade4970 extern: '1' external_id: arxiv: - '2307.00061' pmid: - '38096420' intvolume: ' 382' issue: '6676' keyword: - Stellar Astrophysics language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.48550/arXiv.2307.00061 month: '12' oa: 1 oa_version: None page: 1287-1291 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' related_material: link: - description: News on ISTA Website relation: press_release url: https://ista.ac.at/en/news/reaching-for-the-invisible-stars/ scopus_import: '1' status: public title: An observed population of intermediate-mass helium stars that have been stripped in binaries type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 382 year: '2023' ... --- _id: '11996' abstract: - lang: eng text: If you mix fruit syrups with alcohol to make a schnapps, the two liquids will remain perfectly blended forever. But if you mix oil with vinegar to make a vinaigrette, the oil and vinegar will soon separate back into their previous selves. Such liquid-liquid phase separation is a thermodynamically driven phenomenon and plays an important role in many biological processes (1). Although energy injection at the macroscale can reverse the phase separation—a strong shake is the normal response to a separated vinaigrette—little is known about the effect of energy added at the microscopic level on phase separation. This fundamental question has deep ramifications, notably in biology, because active processes also make the interior of a living cell different from a dead one. On page 768 of this issue, Adkins et al. (2) examine how mechanical activity at the microscopic scale affects liquid-liquid phase separation and allows liquids to climb surfaces. article_processing_charge: No article_type: letter_note author: - first_name: Jérémie A full_name: Palacci, Jérémie A id: 8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d last_name: Palacci orcid: 0000-0002-7253-9465 citation: ama: Palacci JA. A soft active matter that can climb walls. Science. 2022;377(6607):710-711. doi:10.1126/science.adc9202 apa: Palacci, J. A. (2022). A soft active matter that can climb walls. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.adc9202 chicago: Palacci, Jérémie A. “A Soft Active Matter That Can Climb Walls.” Science. American Association for the Advancement of Science, 2022. https://doi.org/10.1126/science.adc9202. ieee: J. A. Palacci, “A soft active matter that can climb walls,” Science, vol. 377, no. 6607. American Association for the Advancement of Science, pp. 710–711, 2022. ista: Palacci JA. 2022. A soft active matter that can climb walls. Science. 377(6607), 710–711. mla: Palacci, Jérémie A. “A Soft Active Matter That Can Climb Walls.” Science, vol. 377, no. 6607, American Association for the Advancement of Science, 2022, pp. 710–11, doi:10.1126/science.adc9202. short: J.A. Palacci, Science 377 (2022) 710–711. date_created: 2022-08-28T22:02:00Z date_published: 2022-08-12T00:00:00Z date_updated: 2022-09-05T07:37:37Z day: '12' department: - _id: JePa doi: 10.1126/science.adc9202 external_id: pmid: - '35951689 ' intvolume: ' 377' issue: '6607' language: - iso: eng month: '08' oa_version: None page: 710-711 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: A soft active matter that can climb walls type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 377 year: '2022' ... --- _id: '10713' abstract: - lang: eng text: Cells migrate through crowded microenvironments within tissues during normal development, immune response, and cancer metastasis. Although migration through pores and tracks in the extracellular matrix (ECM) has been well studied, little is known about cellular traversal into confining cell-dense tissues. We find that embryonic tissue invasion by Drosophila macrophages requires division of an epithelial ectodermal cell at the site of entry. Dividing ectodermal cells disassemble ECM attachment formed by integrin-mediated focal adhesions next to mesodermal cells, allowing macrophages to move their nuclei ahead and invade between two immediately adjacent tissues. Invasion efficiency depends on division frequency, but reduction of adhesion strength allows macrophage entry independently of division. This work demonstrates that tissue dynamics can regulate cellular infiltration. acknowledged_ssus: - _id: Bio acknowledgement: 'We thank J. Friml, C. Guet, T. Hurd, M. Fendrych and members of the laboratory for comments on the manuscript; the Bioimaging Facility of IST Austria for excellent support and T. Lecuit, E. Hafen, R. Levayer and A. Martin for fly strains. This work was supported by a grant from the Austrian Science Fund FWF: Lise Meitner Fellowship M2379-B28 to M.A and D.S., and internal funding from IST Austria to D.S. and EMBL to S.D.R.' article_processing_charge: No article_type: original author: - first_name: Maria full_name: Akhmanova, Maria id: 3425EC26-F248-11E8-B48F-1D18A9856A87 last_name: Akhmanova orcid: 0000-0003-1522-3162 - first_name: Shamsi full_name: Emtenani, Shamsi id: 49D32318-F248-11E8-B48F-1D18A9856A87 last_name: Emtenani orcid: 0000-0001-6981-6938 - first_name: Daniel full_name: Krueger, Daniel last_name: Krueger - first_name: Attila full_name: György, Attila id: 3BCEDBE0-F248-11E8-B48F-1D18A9856A87 last_name: György orcid: 0000-0002-1819-198X - first_name: Mariana full_name: Pereira Guarda, Mariana id: 6de81d9d-e2f2-11eb-945a-af8bc2a60b26 last_name: Pereira Guarda - first_name: Mikhail full_name: Vlasov, Mikhail last_name: Vlasov - first_name: Fedor full_name: Vlasov, Fedor last_name: Vlasov - first_name: Andrei full_name: Akopian, Andrei last_name: Akopian - first_name: Aparna full_name: Ratheesh, Aparna id: 2F064CFE-F248-11E8-B48F-1D18A9856A87 last_name: Ratheesh - first_name: Stefano full_name: De Renzis, Stefano last_name: De Renzis - first_name: Daria E full_name: Siekhaus, Daria E id: 3D224B9E-F248-11E8-B48F-1D18A9856A87 last_name: Siekhaus orcid: 0000-0001-8323-8353 citation: ama: Akhmanova M, Emtenani S, Krueger D, et al. Cell division in tissues enables macrophage infiltration. Science. 2022;376(6591):394-396. doi:10.1126/science.abj0425 apa: Akhmanova, M., Emtenani, S., Krueger, D., György, A., Pereira Guarda, M., Vlasov, M., … Siekhaus, D. E. (2022). Cell division in tissues enables macrophage infiltration. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.abj0425 chicago: Akhmanova, Maria, Shamsi Emtenani, Daniel Krueger, Attila György, Mariana Pereira Guarda, Mikhail Vlasov, Fedor Vlasov, et al. “Cell Division in Tissues Enables Macrophage Infiltration.” Science. American Association for the Advancement of Science, 2022. https://doi.org/10.1126/science.abj0425. ieee: M. Akhmanova et al., “Cell division in tissues enables macrophage infiltration,” Science, vol. 376, no. 6591. American Association for the Advancement of Science, pp. 394–396, 2022. ista: Akhmanova M, Emtenani S, Krueger D, György A, Pereira Guarda M, Vlasov M, Vlasov F, Akopian A, Ratheesh A, De Renzis S, Siekhaus DE. 2022. Cell division in tissues enables macrophage infiltration. Science. 376(6591), 394–396. mla: Akhmanova, Maria, et al. “Cell Division in Tissues Enables Macrophage Infiltration.” Science, vol. 376, no. 6591, American Association for the Advancement of Science, 2022, pp. 394–96, doi:10.1126/science.abj0425. short: M. Akhmanova, S. Emtenani, D. Krueger, A. György, M. Pereira Guarda, M. Vlasov, F. Vlasov, A. Akopian, A. Ratheesh, S. De Renzis, D.E. Siekhaus, Science 376 (2022) 394–396. date_created: 2022-02-01T11:23:18Z date_published: 2022-04-22T00:00:00Z date_updated: 2023-08-02T14:06:15Z day: '22' department: - _id: DaSi doi: 10.1126/science.abj0425 external_id: isi: - '000788553700039' pmid: - '35446632' intvolume: ' 376' isi: 1 issue: '6591' language: - iso: eng license: https://creativecommons.org/licenses/by-nc-nd/4.0/ main_file_link: - open_access: '1' url: https://doi.org/10.1101/2021.04.19.438995 month: '04' oa: 1 oa_version: Preprint page: 394-396 pmid: 1 project: - _id: 264CBBAC-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: M02379 name: Modeling epithelial tissue mechanics during cell invasion publication: Science publication_identifier: issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' status: public title: Cell division in tissues enables macrophage infiltration tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: journal_article user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8 volume: 376 year: '2022' ... --- _id: '12116' abstract: - lang: eng text: Russia’s unprovoked attack on Ukraine has destroyed civilian infrastructure, including universities, research centers, and other academic infrastructure (1). Many Ukrainian scholars and researchers remain in Ukraine, and their work has suffered from major setbacks (2–4). We call on international scientists and institutions to support them. article_processing_charge: No article_type: letter_note author: - first_name: Karishma full_name: Chhugani, Karishma last_name: Chhugani - first_name: Alina full_name: Frolova, Alina last_name: Frolova - first_name: Yuriy full_name: Salyha, Yuriy last_name: Salyha - first_name: Andrada full_name: Fiscutean, Andrada last_name: Fiscutean - first_name: Oksana full_name: Zlenko, Oksana last_name: Zlenko - first_name: Sanita full_name: Reinsone, Sanita last_name: Reinsone - first_name: Walter W. full_name: Wolfsberger, Walter W. last_name: Wolfsberger - first_name: Oleksandra V. full_name: Ivashchenko, Oleksandra V. last_name: Ivashchenko - first_name: Megi full_name: Maci, Megi last_name: Maci - first_name: Dmytro full_name: Dziuba, Dmytro last_name: Dziuba - first_name: Andrii full_name: Parkhomenko, Andrii last_name: Parkhomenko - first_name: Eric full_name: Bortz, Eric last_name: Bortz - first_name: Fyodor full_name: Kondrashov, Fyodor id: 44FDEF62-F248-11E8-B48F-1D18A9856A87 last_name: Kondrashov orcid: 0000-0001-8243-4694 - first_name: Paweł P. full_name: Łabaj, Paweł P. last_name: Łabaj - first_name: Veronika full_name: Romero, Veronika last_name: Romero - first_name: Jakub full_name: Hlávka, Jakub last_name: Hlávka - first_name: Taras K. full_name: Oleksyk, Taras K. last_name: Oleksyk - first_name: Serghei full_name: Mangul, Serghei last_name: Mangul citation: ama: Chhugani K, Frolova A, Salyha Y, et al. Remote opportunities for scholars in Ukraine. Science. 2022;378(6626):1285-1286. doi:10.1126/science.adg0797 apa: Chhugani, K., Frolova, A., Salyha, Y., Fiscutean, A., Zlenko, O., Reinsone, S., … Mangul, S. (2022). Remote opportunities for scholars in Ukraine. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.adg0797 chicago: Chhugani, Karishma, Alina Frolova, Yuriy Salyha, Andrada Fiscutean, Oksana Zlenko, Sanita Reinsone, Walter W. Wolfsberger, et al. “Remote Opportunities for Scholars in Ukraine.” Science. American Association for the Advancement of Science, 2022. https://doi.org/10.1126/science.adg0797. ieee: K. Chhugani et al., “Remote opportunities for scholars in Ukraine,” Science, vol. 378, no. 6626. American Association for the Advancement of Science, pp. 1285–1286, 2022. ista: Chhugani K, Frolova A, Salyha Y, Fiscutean A, Zlenko O, Reinsone S, Wolfsberger WW, Ivashchenko OV, Maci M, Dziuba D, Parkhomenko A, Bortz E, Kondrashov F, Łabaj PP, Romero V, Hlávka J, Oleksyk TK, Mangul S. 2022. Remote opportunities for scholars in Ukraine. Science. 378(6626), 1285–1286. mla: Chhugani, Karishma, et al. “Remote Opportunities for Scholars in Ukraine.” Science, vol. 378, no. 6626, American Association for the Advancement of Science, 2022, pp. 1285–86, doi:10.1126/science.adg0797. short: K. Chhugani, A. Frolova, Y. Salyha, A. Fiscutean, O. Zlenko, S. Reinsone, W.W. Wolfsberger, O.V. Ivashchenko, M. Maci, D. Dziuba, A. Parkhomenko, E. Bortz, F. Kondrashov, P.P. Łabaj, V. Romero, J. Hlávka, T.K. Oleksyk, S. Mangul, Science 378 (2022) 1285–1286. date_created: 2023-01-12T11:56:30Z date_published: 2022-12-22T00:00:00Z date_updated: 2023-10-03T11:01:06Z day: '22' department: - _id: FyKo doi: 10.1126/science.adg0797 external_id: isi: - '000963463700023' intvolume: ' 378' isi: 1 issue: '6626' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1126/science.adg0797 month: '12' oa: 1 oa_version: Published Version page: 1285-1286 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Remote opportunities for scholars in Ukraine type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 378 year: '2022' ... --- _id: '14282' abstract: - lang: eng text: Asymmetric multiprotein complexes that undergo subunit exchange play central roles in biology but present a challenge for design because the components must not only contain interfaces that enable reversible association but also be stable and well behaved in isolation. We use implicit negative design to generate β sheet–mediated heterodimers that can be assembled into a wide variety of complexes. The designs are stable, folded, and soluble in isolation and rapidly assemble upon mixing, and crystal structures are close to the computational models. We construct linearly arranged hetero-oligomers with up to six different components, branched hetero-oligomers, closed C4-symmetric two-component rings, and hetero-oligomers assembled on a cyclic homo-oligomeric central hub and demonstrate that such complexes can readily reconfigure through subunit exchange. Our approach provides a general route to designing asymmetric reconfigurable protein systems. article_number: abj7662 article_processing_charge: No article_type: original author: - first_name: Danny D. full_name: Sahtoe, Danny D. last_name: Sahtoe - first_name: Florian M full_name: Praetorius, Florian M id: dfec9381-4341-11ee-8fd8-faa02bba7d62 last_name: Praetorius - first_name: Alexis full_name: Courbet, Alexis last_name: Courbet - first_name: Yang full_name: Hsia, Yang last_name: Hsia - first_name: Basile I. M. full_name: Wicky, Basile I. M. last_name: Wicky - first_name: Natasha I. full_name: Edman, Natasha I. last_name: Edman - first_name: Lauren M. full_name: Miller, Lauren M. last_name: Miller - first_name: Bart J. R. full_name: Timmermans, Bart J. R. last_name: Timmermans - first_name: Justin full_name: Decarreau, Justin last_name: Decarreau - first_name: Hana M. full_name: Morris, Hana M. last_name: Morris - first_name: Alex full_name: Kang, Alex last_name: Kang - first_name: Asim K. full_name: Bera, Asim K. last_name: Bera - first_name: David full_name: Baker, David last_name: Baker citation: ama: Sahtoe DD, Praetorius FM, Courbet A, et al. Reconfigurable asymmetric protein assemblies through implicit negative design. Science. 2022;375(6578). doi:10.1126/science.abj7662 apa: Sahtoe, D. D., Praetorius, F. M., Courbet, A., Hsia, Y., Wicky, B. I. M., Edman, N. I., … Baker, D. (2022). Reconfigurable asymmetric protein assemblies through implicit negative design. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.abj7662 chicago: Sahtoe, Danny D., Florian M Praetorius, Alexis Courbet, Yang Hsia, Basile I. M. Wicky, Natasha I. Edman, Lauren M. Miller, et al. “Reconfigurable Asymmetric Protein Assemblies through Implicit Negative Design.” Science. American Association for the Advancement of Science, 2022. https://doi.org/10.1126/science.abj7662. ieee: D. D. Sahtoe et al., “Reconfigurable asymmetric protein assemblies through implicit negative design,” Science, vol. 375, no. 6578. American Association for the Advancement of Science, 2022. ista: Sahtoe DD, Praetorius FM, Courbet A, Hsia Y, Wicky BIM, Edman NI, Miller LM, Timmermans BJR, Decarreau J, Morris HM, Kang A, Bera AK, Baker D. 2022. Reconfigurable asymmetric protein assemblies through implicit negative design. Science. 375(6578), abj7662. mla: Sahtoe, Danny D., et al. “Reconfigurable Asymmetric Protein Assemblies through Implicit Negative Design.” Science, vol. 375, no. 6578, abj7662, American Association for the Advancement of Science, 2022, doi:10.1126/science.abj7662. short: D.D. Sahtoe, F.M. Praetorius, A. Courbet, Y. Hsia, B.I.M. Wicky, N.I. Edman, L.M. Miller, B.J.R. Timmermans, J. Decarreau, H.M. Morris, A. Kang, A.K. Bera, D. Baker, Science 375 (2022). date_created: 2023-09-06T12:05:42Z date_published: 2022-01-21T00:00:00Z date_updated: 2023-11-07T12:39:56Z day: '21' doi: 10.1126/science.abj7662 extern: '1' external_id: pmid: - '35050655' intvolume: ' 375' issue: '6578' language: - iso: eng month: '01' oa_version: None pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Reconfigurable asymmetric protein assemblies through implicit negative design type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 375 year: '2022' ... --- _id: '10616' abstract: - lang: eng text: Electrons in moiré flat band systems can spontaneously break time-reversal symmetry, giving rise to a quantized anomalous Hall effect. In this study, we use a superconducting quantum interference device to image stray magnetic fields in twisted bilayer graphene aligned to hexagonal boron nitride. We find a magnetization of several Bohr magnetons per charge carrier, demonstrating that the magnetism is primarily orbital in nature. Our measurements reveal a large change in the magnetization as the chemical potential is swept across the quantum anomalous Hall gap, consistent with the expected contribution of chiral edge states to the magnetization of an orbital Chern insulator. Mapping the spatial evolution of field-driven magnetic reversal, we find a series of reproducible micrometer-scale domains pinned to structural disorder. acknowledgement: 'We thank A. H. Macdonald, J. Zhu, M. Zaletel, and D. Xiao for discussions of the results and E. Lachman for comments on the manuscript. Funding: The work was primarily funded by the US Department of Energy under DE-SC0020043, with additional support for instrumentation development supported by the Army Research Office under grant W911NF-16-1-0361. K.W. and T.T. acknowledge support from the Elemental Strategy Initiative conducted by MEXT, Japan, grant JPMXP0112101001; JSPS KAKENHI grant JP20H00354 and CREST grant JPMJCR15F3, JST. C.L.T. acknowledges support from the Hertz Foundation and from the National Science Foundation Graduate Research Fellowship Program under grant 1650114. This project is funded in part by the Gordon and Betty Moore Foundation’s EPiQS Initiative, grant GBMF9471 to A.F.Y.' article_processing_charge: No article_type: original author: - first_name: C. L. full_name: Tschirhart, C. L. last_name: Tschirhart - first_name: M. full_name: Serlin, M. last_name: Serlin - first_name: Hryhoriy full_name: Polshyn, Hryhoriy id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48 last_name: Polshyn orcid: 0000-0001-8223-8896 - first_name: A. full_name: Shragai, A. last_name: Shragai - first_name: Z. full_name: Xia, Z. last_name: Xia - first_name: J. full_name: Zhu, J. last_name: Zhu - first_name: Y. full_name: Zhang, Y. last_name: Zhang - first_name: K. full_name: Watanabe, K. last_name: Watanabe - first_name: T. full_name: Taniguchi, T. last_name: Taniguchi - first_name: M. E. full_name: Huber, M. E. last_name: Huber - first_name: A. F. full_name: Young, A. F. last_name: Young citation: ama: Tschirhart CL, Serlin M, Polshyn H, et al. Imaging orbital ferromagnetism in a moiré Chern insulator. Science. 2021;372(6548):1323-1327. doi:10.1126/science.abd3190 apa: Tschirhart, C. L., Serlin, M., Polshyn, H., Shragai, A., Xia, Z., Zhu, J., … Young, A. F. (2021). Imaging orbital ferromagnetism in a moiré Chern insulator. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.abd3190 chicago: Tschirhart, C. L., M. Serlin, Hryhoriy Polshyn, A. Shragai, Z. Xia, J. Zhu, Y. Zhang, et al. “Imaging Orbital Ferromagnetism in a Moiré Chern Insulator.” Science. American Association for the Advancement of Science, 2021. https://doi.org/10.1126/science.abd3190. ieee: C. L. Tschirhart et al., “Imaging orbital ferromagnetism in a moiré Chern insulator,” Science, vol. 372, no. 6548. American Association for the Advancement of Science, pp. 1323–1327, 2021. ista: Tschirhart CL, Serlin M, Polshyn H, Shragai A, Xia Z, Zhu J, Zhang Y, Watanabe K, Taniguchi T, Huber ME, Young AF. 2021. Imaging orbital ferromagnetism in a moiré Chern insulator. Science. 372(6548), 1323–1327. mla: Tschirhart, C. L., et al. “Imaging Orbital Ferromagnetism in a Moiré Chern Insulator.” Science, vol. 372, no. 6548, American Association for the Advancement of Science, 2021, pp. 1323–27, doi:10.1126/science.abd3190. short: C.L. Tschirhart, M. Serlin, H. Polshyn, A. Shragai, Z. Xia, J. Zhu, Y. Zhang, K. Watanabe, T. Taniguchi, M.E. Huber, A.F. Young, Science 372 (2021) 1323–1327. date_created: 2022-01-13T12:17:45Z date_published: 2021-05-27T00:00:00Z date_updated: 2022-01-13T14:11:36Z day: '27' doi: 10.1126/science.abd3190 extern: '1' external_id: arxiv: - '2006.08053' pmid: - '34045322' intvolume: ' 372' issue: '6548' keyword: - multidisciplinary language: - iso: eng main_file_link: - open_access: '1' url: https://arxiv.org/abs/2006.08053 month: '05' oa: 1 oa_version: Preprint page: 1323-1327 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Imaging orbital ferromagnetism in a moiré Chern insulator type: journal_article user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9 volume: 372 year: '2021' ... --- _id: '12187' abstract: - lang: eng text: Genomes of germ cells present an existential vulnerability to organisms because germ cell mutations will propagate to future generations. Transposable elements are one source of such mutations. In the small flowering plant Arabidopsis, Long et al. found that genome methylation in the male germline is directed by small interfering RNAs (siRNAs) imperfectly transcribed from transposons (see the Perspective by Mosher). These germline siRNAs silence germline transposons and establish inherited methylation patterns in sperm, thus maintaining the integrity of the plant genome across generations. acknowledgement: 'We thank the John Innes Centre Bioimaging Facility (S. Lopez, E. Wegel, and K. Findlay) for their assistance with microscopy and the Norwich BioScience Institute Partnership Computing Infrastructure for Science Group for high-performance computing resources. Funding: This work was funded by a European Research Council Starting Grant (“SexMeth” 804981; J.L., J.W., and X.F.), a Sainsbury Charitable Foundation studentship (J.W.), two Biotechnology and Biological Sciences Research Council (BBSRC) grants (BBS0096201 and BBP0135111; W.S., M.V., and X.F.), two John Innes Foundation studentships (B.A. and S.D.), and a BBSRC David Phillips Fellowship (BBL0250431; H.G. and X.F.). Author contributions: J.L., J.W., and X.F. designed the study and wrote the manuscript; J.L., W.S., B.A., H.G., and S.D. performed the experiments; and J.L., J.W., B.A., H.G., S.D., M.V., and X.F. analyzed the data. Competing interests: The authors declare no competing interests. Data and material availability: All sequencing data have been deposited in the Gene Expression Omnibus (GEO) under accession no. GSE161625. Accession nos. of published datasets used in this study are listed in table S6. Published software used in this study include Bowtie v1.2.2 (https://doi.org/10.1002/0471250953.bi1107s32), Bismark v0.22.2 (https://doi.org/10.1093/bioinformatics/btr167), Kallisto v0.43.0 (https://doi.org/10.1038/nbt0816-888d), Shortstack v3.8.5 (https://doi.org/10.1534/g3.116.030452), and Cutadapt v1.15 (https://doi.org/10.1089/cmb.2017.0096). TrimGalore v0.4.1 and MarkDuplicates v1.141 are available from https://github.com/FelixKrueger/TrimGalore and https://github.com/broadinstitute/picard, respectively. All remaining data are in the main paper or the supplementary materials.' article_processing_charge: No article_type: original author: - first_name: Jincheng full_name: Long, Jincheng last_name: Long - first_name: James full_name: Walker, James last_name: Walker - first_name: Wenjing full_name: She, Wenjing last_name: She - first_name: Billy full_name: Aldridge, Billy last_name: Aldridge - first_name: Hongbo full_name: Gao, Hongbo last_name: Gao - first_name: Samuel full_name: Deans, Samuel last_name: Deans - first_name: Martin full_name: Vickers, Martin last_name: Vickers - first_name: Xiaoqi full_name: Feng, Xiaoqi id: e0164712-22ee-11ed-b12a-d80fcdf35958 last_name: Feng orcid: 0000-0002-4008-1234 citation: ama: Long J, Walker J, She W, et al. Nurse cell--derived small RNAs define paternal epigenetic inheritance in Arabidopsis. Science. 2021;373(6550). doi:10.1126/science.abh0556 apa: Long, J., Walker, J., She, W., Aldridge, B., Gao, H., Deans, S., … Feng, X. (2021). Nurse cell--derived small RNAs define paternal epigenetic inheritance in Arabidopsis. Science. American Association for the Advancement of Science (AAAS). https://doi.org/10.1126/science.abh0556 chicago: Long, Jincheng, James Walker, Wenjing She, Billy Aldridge, Hongbo Gao, Samuel Deans, Martin Vickers, and Xiaoqi Feng. “Nurse Cell--Derived Small RNAs Define Paternal Epigenetic Inheritance in Arabidopsis.” Science. American Association for the Advancement of Science (AAAS), 2021. https://doi.org/10.1126/science.abh0556. ieee: J. Long et al., “Nurse cell--derived small RNAs define paternal epigenetic inheritance in Arabidopsis,” Science, vol. 373, no. 6550. American Association for the Advancement of Science (AAAS), 2021. ista: Long J, Walker J, She W, Aldridge B, Gao H, Deans S, Vickers M, Feng X. 2021. Nurse cell--derived small RNAs define paternal epigenetic inheritance in Arabidopsis. Science. 373(6550). mla: Long, Jincheng, et al. “Nurse Cell--Derived Small RNAs Define Paternal Epigenetic Inheritance in Arabidopsis.” Science, vol. 373, no. 6550, American Association for the Advancement of Science (AAAS), 2021, doi:10.1126/science.abh0556. short: J. Long, J. Walker, W. She, B. Aldridge, H. Gao, S. Deans, M. Vickers, X. Feng, Science 373 (2021). date_created: 2023-01-16T09:15:14Z date_published: 2021-07-02T00:00:00Z date_updated: 2023-05-08T10:56:39Z day: '02' department: - _id: XiFe doi: 10.1126/science.abh0556 extern: '1' external_id: pmid: - '34210850' intvolume: ' 373' issue: '6550' keyword: - Multidisciplinary language: - iso: eng month: '07' oa_version: None pmid: 1 publication: Science publication_identifier: issn: - 0036-8075 - 1095-9203 publication_status: published publisher: American Association for the Advancement of Science (AAAS) quality_controlled: '1' scopus_import: '1' status: public title: Nurse cell--derived small RNAs define paternal epigenetic inheritance in Arabidopsis type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 373 year: '2021' ... --- _id: '9618' abstract: - lang: eng text: The control of nonequilibrium quantum dynamics in many-body systems is challenging because interactions typically lead to thermalization and a chaotic spreading throughout Hilbert space. We investigate nonequilibrium dynamics after rapid quenches in a many-body system composed of 3 to 200 strongly interacting qubits in one and two spatial dimensions. Using a programmable quantum simulator based on Rydberg atom arrays, we show that coherent revivals associated with so-called quantum many-body scars can be stabilized by periodic driving, which generates a robust subharmonic response akin to discrete time-crystalline order. We map Hilbert space dynamics, geometry dependence, phase diagrams, and system-size dependence of this emergent phenomenon, demonstrating new ways to steer complex dynamics in many-body systems and enabling potential applications in quantum information science. acknowledgement: 'We thank many members of the Harvard AMO community, particularly E. Urbach, S. Dakoulas, and J. Doyle for their efforts enabling safe and productive operation of our laboratories during 2020. We thank D. Abanin, I. Cong, F. Machado, H. Pichler, N. Yao, B. Ye, and H. Zhou for stimulating discussions. Funding: We acknowledge financial support from the Center for Ultracold Atoms, the National Science Foundation, the Vannevar Bush Faculty Fellowship, the U.S. Department of Energy (LBNL QSA Center and grant no. DE-SC0021013), the Office of Naval Research, the Army Research Office MURI, the DARPA DRINQS program (grant no. D18AC00033), and the DARPA ONISQ program (grant no. W911NF2010021). The authors acknowledge support from the NSF Graduate Research Fellowship Program (grant DGE1745303) and The Fannie and John Hertz Foundation (D.B.); a National Defense Science and Engineering Graduate (NDSEG) fellowship (H.L.); a fellowship from the Max Planck/Harvard Research Center for Quantum Optics (G.S.); Gordon College (T.T.W.); the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant agreement no. 850899) (A.A.M. and M.S.); a Department of Energy Computational Science Graduate Fellowship under award number DE-SC0021110 (N.M.); the Moore Foundation’s EPiQS Initiative grant no. GBMF4306, the NUS Development grant AY2019/2020, and the Stanford Institute of Theoretical Physics (W.W.H.); and the Miller Institute for Basic Research in Science (S.C.). Author contributions: D.B., A.O., H.L., A.K., G.S., S.E., and T.T.W. contributed to the building of the experimental setup, performed the measurements, and analyzed the data. A.A.M., N.M., W.W.H., S.C., and M.S. performed theoretical analysis. All work was supervised by M.G., V.V., and M.D.L. All authors discussed the results and contributed to the manuscript. Competing interests: M.G., V.V., and M.D.L. are co-founders and shareholders of QuEra Computing. A.O. is a shareholder of QuEra Computing. Data and materials availability: All data needed to evaluate the conclusions in the paper are present in the paper and the supplementary materials.' article_processing_charge: No article_type: original author: - first_name: D. full_name: Bluvstein, D. last_name: Bluvstein - first_name: A. full_name: Omran, A. last_name: Omran - first_name: H. full_name: Levine, H. last_name: Levine - first_name: A. full_name: Keesling, A. last_name: Keesling - first_name: G. full_name: Semeghini, G. last_name: Semeghini - first_name: S. full_name: Ebadi, S. last_name: Ebadi - first_name: T. T. full_name: Wang, T. T. last_name: Wang - first_name: Alexios full_name: Michailidis, Alexios id: 36EBAD38-F248-11E8-B48F-1D18A9856A87 last_name: Michailidis orcid: 0000-0002-8443-1064 - first_name: N. full_name: Maskara, N. last_name: Maskara - first_name: W. W. full_name: Ho, W. W. last_name: Ho - first_name: S. full_name: Choi, S. last_name: Choi - first_name: Maksym full_name: Serbyn, Maksym id: 47809E7E-F248-11E8-B48F-1D18A9856A87 last_name: Serbyn orcid: 0000-0002-2399-5827 - first_name: M. full_name: Greiner, M. last_name: Greiner - first_name: V. full_name: Vuletić, V. last_name: Vuletić - first_name: M. D. full_name: Lukin, M. D. last_name: Lukin citation: ama: Bluvstein D, Omran A, Levine H, et al. Controlling quantum many-body dynamics in driven Rydberg atom arrays. Science. 2021;371(6536):1355-1359. doi:10.1126/science.abg2530 apa: Bluvstein, D., Omran, A., Levine, H., Keesling, A., Semeghini, G., Ebadi, S., … Lukin, M. D. (2021). Controlling quantum many-body dynamics in driven Rydberg atom arrays. Science. AAAS. https://doi.org/10.1126/science.abg2530 chicago: Bluvstein, D., A. Omran, H. Levine, A. Keesling, G. Semeghini, S. Ebadi, T. T. Wang, et al. “Controlling Quantum Many-Body Dynamics in Driven Rydberg Atom Arrays.” Science. AAAS, 2021. https://doi.org/10.1126/science.abg2530. ieee: D. Bluvstein et al., “Controlling quantum many-body dynamics in driven Rydberg atom arrays,” Science, vol. 371, no. 6536. AAAS, pp. 1355–1359, 2021. ista: Bluvstein D, Omran A, Levine H, Keesling A, Semeghini G, Ebadi S, Wang TT, Michailidis A, Maskara N, Ho WW, Choi S, Serbyn M, Greiner M, Vuletić V, Lukin MD. 2021. Controlling quantum many-body dynamics in driven Rydberg atom arrays. Science. 371(6536), 1355–1359. mla: Bluvstein, D., et al. “Controlling Quantum Many-Body Dynamics in Driven Rydberg Atom Arrays.” Science, vol. 371, no. 6536, AAAS, 2021, pp. 1355–59, doi:10.1126/science.abg2530. short: D. Bluvstein, A. Omran, H. Levine, A. Keesling, G. Semeghini, S. Ebadi, T.T. Wang, A. Michailidis, N. Maskara, W.W. Ho, S. Choi, M. Serbyn, M. Greiner, V. Vuletić, M.D. Lukin, Science 371 (2021) 1355–1359. date_created: 2021-06-29T12:04:05Z date_published: 2021-03-26T00:00:00Z date_updated: 2023-08-10T13:57:07Z day: '26' ddc: - '539' department: - _id: MaSe doi: 10.1126/science.abg2530 ec_funded: 1 external_id: arxiv: - '2012.12276' isi: - '000636043400048' pmid: - '33632894' file: - access_level: open_access checksum: 0b356fd10ab9bb95177d4c047d4e9c1a content_type: application/pdf creator: patrickd date_created: 2021-09-23T14:00:05Z date_updated: 2021-09-23T14:00:05Z file_id: '10040' file_name: scars_subharmonic_combined_manuscript_2_11_2021 (2)-1.pdf file_size: 3671159 relation: main_file success: 1 file_date_updated: 2021-09-23T14:00:05Z has_accepted_license: '1' intvolume: ' 371' isi: 1 issue: '6536' keyword: - Multidisciplinary language: - iso: eng month: '03' oa: 1 oa_version: Preprint page: 1355-1359 pmid: 1 project: - _id: 23841C26-32DE-11EA-91FC-C7463DDC885E call_identifier: H2020 grant_number: '850899' name: 'Non-Ergodic Quantum Matter: Universality, Dynamics and Control' publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: AAAS quality_controlled: '1' scopus_import: '1' status: public title: Controlling quantum many-body dynamics in driven Rydberg atom arrays type: journal_article user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8 volume: 371 year: '2021' ... --- _id: '10809' abstract: - lang: eng text: Thermoelectric materials are engines that convert heat into an electrical current. Intuitively, the efficiency of this process depends on how many electrons (charge carriers) can move and how easily they do so, how much energy those moving electrons transport, and how easily the temperature gradient is maintained. In terms of material properties, an excellent thermoelectric material requires a high electrical conductivity σ, a high Seebeck coefficient S (a measure of the induced thermoelectric voltage as a function of temperature gradient), and a low thermal conductivity κ. The challenge is that these three properties are strongly interrelated in a conflicting manner (1). On page 722 of this issue, Roychowdhury et al. (2) have found a way to partially break these ties in silver antimony telluride (AgSbTe2) with the addition of cadmium (Cd) cations, which increase the ordering in this inherently disordered thermoelectric material. article_processing_charge: No article_type: letter_note author: - first_name: Yu full_name: Liu, Yu id: 2A70014E-F248-11E8-B48F-1D18A9856A87 last_name: Liu orcid: 0000-0001-7313-6740 - first_name: Maria full_name: Ibáñez, Maria id: 43C61214-F248-11E8-B48F-1D18A9856A87 last_name: Ibáñez orcid: 0000-0001-5013-2843 citation: ama: Liu Y, Ibáñez M. Tidying up the mess. Science. 2021;371(6530):678-679. doi:10.1126/science.abg0886 apa: Liu, Y., & Ibáñez, M. (2021). Tidying up the mess. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.abg0886 chicago: Liu, Yu, and Maria Ibáñez. “Tidying up the Mess.” Science. American Association for the Advancement of Science, 2021. https://doi.org/10.1126/science.abg0886. ieee: Y. Liu and M. Ibáñez, “Tidying up the mess,” Science, vol. 371, no. 6530. American Association for the Advancement of Science, pp. 678–679, 2021. ista: Liu Y, Ibáñez M. 2021. Tidying up the mess. Science. 371(6530), 678–679. mla: Liu, Yu, and Maria Ibáñez. “Tidying up the Mess.” Science, vol. 371, no. 6530, American Association for the Advancement of Science, 2021, pp. 678–79, doi:10.1126/science.abg0886. short: Y. Liu, M. Ibáñez, Science 371 (2021) 678–679. date_created: 2022-03-03T09:51:48Z date_published: 2021-02-12T00:00:00Z date_updated: 2023-08-17T07:00:35Z day: '12' department: - _id: MaIb doi: 10.1126/science.abg0886 external_id: isi: - '000617551600027' pmid: - '33574201' intvolume: ' 371' isi: 1 issue: '6530' keyword: - multidisciplinary language: - iso: eng month: '02' oa_version: None page: 678-679 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Tidying up the mess type: journal_article user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8 volume: 371 year: '2021' ... --- _id: '10349' abstract: - lang: eng text: Sulfolobus acidocaldarius is the closest experimentally tractable archaeal relative of eukaryotes and, despite lacking obvious cyclin-dependent kinase and cyclin homologs, has an ordered eukaryote-like cell cycle with distinct phases of DNA replication and division. Here, in exploring the mechanism of cell division in S. acidocaldarius, we identify a role for the archaeal proteasome in regulating the transition from the end of one cell cycle to the beginning of the next. Further, we identify the archaeal ESCRT-III homolog, CdvB, as a key target of the proteasome and show that its degradation triggers division by allowing constriction of the CdvB1:CdvB2 ESCRT-III division ring. These findings offer a minimal mechanism for ESCRT-III–mediated membrane remodeling and point to a conserved role for the proteasome in eukaryotic and archaeal cell cycle control. acknowledgement: "We thank the MRC LMCB at UCL for their support; the flow cytometry STP at the Francis Crick Institute for assistance, with special thanks to S. Purewal and D. Davis; C. Bertoli for mentorship\r\nand advice; J. M. Garcia-Arcos for help early on in this project; the entire Baum lab for their input throughout the project; the Albers lab for advice and reagents, with special thanks to M. Van Wolferen and S. Albers; the members of the Wellcome consortium for archaeal cytoskeleton studies for advice and comments; and J. Löwe, S. Oliferenko, M. Balasubramanian, and D. Gerlich for discussions and advice on the manuscript. N.P.R. and S.B. would like to thank N. Rzechorzek, A. Simon, and S. Anjum for discussion and advice." article_processing_charge: No article_type: original author: - first_name: Gabriel full_name: Tarrason Risa, Gabriel last_name: Tarrason Risa - first_name: Fredrik full_name: Hurtig, Fredrik last_name: Hurtig - first_name: Sian full_name: Bray, Sian last_name: Bray - first_name: Anne E. full_name: Hafner, Anne E. last_name: Hafner - first_name: Lena full_name: Harker-Kirschneck, Lena last_name: Harker-Kirschneck - first_name: Peter full_name: Faull, Peter last_name: Faull - first_name: Colin full_name: Davis, Colin last_name: Davis - first_name: Dimitra full_name: Papatziamou, Dimitra last_name: Papatziamou - first_name: Delyan R. full_name: Mutavchiev, Delyan R. last_name: Mutavchiev - first_name: Catherine full_name: Fan, Catherine last_name: Fan - first_name: Leticia full_name: Meneguello, Leticia last_name: Meneguello - first_name: Andre full_name: Arashiro Pulschen, Andre last_name: Arashiro Pulschen - first_name: Gautam full_name: Dey, Gautam last_name: Dey - first_name: Siân full_name: Culley, Siân last_name: Culley - first_name: Mairi full_name: Kilkenny, Mairi last_name: Kilkenny - first_name: Diorge P. full_name: Souza, Diorge P. last_name: Souza - first_name: Luca full_name: Pellegrini, Luca last_name: Pellegrini - first_name: Robertus A. M. full_name: de Bruin, Robertus A. M. last_name: de Bruin - first_name: Ricardo full_name: Henriques, Ricardo last_name: Henriques - first_name: Ambrosius P. full_name: Snijders, Ambrosius P. last_name: Snijders - first_name: Anđela full_name: Šarić, Anđela id: bf63d406-f056-11eb-b41d-f263a6566d8b last_name: Šarić orcid: 0000-0002-7854-2139 - first_name: Ann-Christin full_name: Lindås, Ann-Christin last_name: Lindås - first_name: Nicholas P. full_name: Robinson, Nicholas P. last_name: Robinson - first_name: Buzz full_name: Baum, Buzz last_name: Baum citation: ama: Tarrason Risa G, Hurtig F, Bray S, et al. The proteasome controls ESCRT-III–mediated cell division in an archaeon. Science. 2020;369(6504). doi:10.1126/science.aaz2532 apa: Tarrason Risa, G., Hurtig, F., Bray, S., Hafner, A. E., Harker-Kirschneck, L., Faull, P., … Baum, B. (2020). The proteasome controls ESCRT-III–mediated cell division in an archaeon. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.aaz2532 chicago: Tarrason Risa, Gabriel, Fredrik Hurtig, Sian Bray, Anne E. Hafner, Lena Harker-Kirschneck, Peter Faull, Colin Davis, et al. “The Proteasome Controls ESCRT-III–Mediated Cell Division in an Archaeon.” Science. American Association for the Advancement of Science, 2020. https://doi.org/10.1126/science.aaz2532. ieee: G. Tarrason Risa et al., “The proteasome controls ESCRT-III–mediated cell division in an archaeon,” Science, vol. 369, no. 6504. American Association for the Advancement of Science, 2020. ista: Tarrason Risa G, Hurtig F, Bray S, Hafner AE, Harker-Kirschneck L, Faull P, Davis C, Papatziamou D, Mutavchiev DR, Fan C, Meneguello L, Arashiro Pulschen A, Dey G, Culley S, Kilkenny M, Souza DP, Pellegrini L, de Bruin RAM, Henriques R, Snijders AP, Šarić A, Lindås A-C, Robinson NP, Baum B. 2020. The proteasome controls ESCRT-III–mediated cell division in an archaeon. Science. 369(6504). mla: Tarrason Risa, Gabriel, et al. “The Proteasome Controls ESCRT-III–Mediated Cell Division in an Archaeon.” Science, vol. 369, no. 6504, American Association for the Advancement of Science, 2020, doi:10.1126/science.aaz2532. short: G. Tarrason Risa, F. Hurtig, S. Bray, A.E. Hafner, L. Harker-Kirschneck, P. Faull, C. Davis, D. Papatziamou, D.R. Mutavchiev, C. Fan, L. Meneguello, A. Arashiro Pulschen, G. Dey, S. Culley, M. Kilkenny, D.P. Souza, L. Pellegrini, R.A.M. de Bruin, R. Henriques, A.P. Snijders, A. Šarić, A.-C. Lindås, N.P. Robinson, B. Baum, Science 369 (2020). date_created: 2021-11-26T08:21:34Z date_published: 2020-08-07T00:00:00Z date_updated: 2021-11-26T08:58:33Z day: '07' doi: 10.1126/science.aaz2532 extern: '1' external_id: pmid: - '32764038' intvolume: ' 369' issue: '6504' keyword: - multidisciplinary language: - iso: eng main_file_link: - open_access: '1' url: https://www.biorxiv.org/content/10.1101/774273v1 month: '08' oa: 1 oa_version: Preprint pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: The proteasome controls ESCRT-III–mediated cell division in an archaeon type: journal_article user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9 volume: 369 year: '2020' ... --- _id: '8680' abstract: - lang: eng text: Animal development entails the organization of specific cell types in space and time, and spatial patterns must form in a robust manner. In the zebrafish spinal cord, neural progenitors form stereotypic patterns despite noisy morphogen signaling and large-scale cellular rearrangements during morphogenesis and growth. By directly measuring adhesion forces and preferences for three types of endogenous neural progenitors, we provide evidence for the differential adhesion model in which differences in intercellular adhesion mediate cell sorting. Cell type–specific combinatorial expression of different classes of cadherins (N-cadherin, cadherin 11, and protocadherin 19) results in homotypic preference ex vivo and patterning robustness in vivo. Furthermore, the differential adhesion code is regulated by the sonic hedgehog morphogen gradient. We propose that robust patterning during tissue morphogenesis results from interplay between adhesion-based self-organization and morphogen-directed patterning. acknowledgement: "We thank the members of the Megason and Heisenberg labs for critical discussions of and technical assistance during the work and B. Appel, S. Holley, J. Jontes, and D. Gilmour for transgenic fish. This work is supported by the Damon Runyon Cancer Foundation, a NICHD K99 fellowship (1K99HD092623), a Travelling Fellowship of the Company of Biologists, a Collaborative Research grant from the Burroughs Wellcome Foundation (T.Y.-C.T.), NIH grant 01GM107733 (T.Y.-C.T. and S.G.M.), NIH grant R01NS102322 (T.C.-C. and H.K.), and an ERC advanced grant\r\n(MECSPEC) (C.-P.H.)." article_processing_charge: No article_type: original author: - first_name: Tony Y.-C. full_name: Tsai, Tony Y.-C. last_name: Tsai - first_name: Mateusz K full_name: Sikora, Mateusz K id: 2F74BCDE-F248-11E8-B48F-1D18A9856A87 last_name: Sikora - first_name: Peng full_name: Xia, Peng id: 4AB6C7D0-F248-11E8-B48F-1D18A9856A87 last_name: Xia orcid: 0000-0002-5419-7756 - first_name: Tugba full_name: Colak-Champollion, Tugba last_name: Colak-Champollion - first_name: Holger full_name: Knaut, Holger last_name: Knaut - first_name: Carl-Philipp J full_name: Heisenberg, Carl-Philipp J id: 39427864-F248-11E8-B48F-1D18A9856A87 last_name: Heisenberg orcid: 0000-0002-0912-4566 - first_name: Sean G. full_name: Megason, Sean G. last_name: Megason citation: ama: Tsai TY-C, Sikora MK, Xia P, et al. An adhesion code ensures robust pattern formation during tissue morphogenesis. Science. 2020;370(6512):113-116. doi:10.1126/science.aba6637 apa: Tsai, T. Y.-C., Sikora, M. K., Xia, P., Colak-Champollion, T., Knaut, H., Heisenberg, C.-P. J., & Megason, S. G. (2020). An adhesion code ensures robust pattern formation during tissue morphogenesis. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.aba6637 chicago: Tsai, Tony Y.-C., Mateusz K Sikora, Peng Xia, Tugba Colak-Champollion, Holger Knaut, Carl-Philipp J Heisenberg, and Sean G. Megason. “An Adhesion Code Ensures Robust Pattern Formation during Tissue Morphogenesis.” Science. American Association for the Advancement of Science, 2020. https://doi.org/10.1126/science.aba6637. ieee: T. Y.-C. Tsai et al., “An adhesion code ensures robust pattern formation during tissue morphogenesis,” Science, vol. 370, no. 6512. American Association for the Advancement of Science, pp. 113–116, 2020. ista: Tsai TY-C, Sikora MK, Xia P, Colak-Champollion T, Knaut H, Heisenberg C-PJ, Megason SG. 2020. An adhesion code ensures robust pattern formation during tissue morphogenesis. Science. 370(6512), 113–116. mla: Tsai, Tony Y. C., et al. “An Adhesion Code Ensures Robust Pattern Formation during Tissue Morphogenesis.” Science, vol. 370, no. 6512, American Association for the Advancement of Science, 2020, pp. 113–16, doi:10.1126/science.aba6637. short: T.Y.-C. Tsai, M.K. Sikora, P. Xia, T. Colak-Champollion, H. Knaut, C.-P.J. Heisenberg, S.G. Megason, Science 370 (2020) 113–116. date_created: 2020-10-19T14:09:38Z date_published: 2020-10-02T00:00:00Z date_updated: 2023-08-22T10:36:35Z day: '02' department: - _id: CaHe doi: 10.1126/science.aba6637 ec_funded: 1 external_id: isi: - '000579169000053' intvolume: ' 370' isi: 1 issue: '6512' keyword: - Multidisciplinary language: - iso: eng main_file_link: - open_access: '1' url: https://www.biorxiv.org/content/10.1101/803635v1 month: '10' oa: 1 oa_version: Preprint page: 113-116 project: - _id: 260F1432-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '742573' name: Interaction and feedback between cell mechanics and fate specification in vertebrate gastrulation publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' related_material: link: - description: News on IST Homepage relation: press_release url: https://ist.ac.at/en/news/sticking-together/ scopus_import: '1' status: public title: An adhesion code ensures robust pattern formation during tissue morphogenesis type: journal_article user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8 volume: 370 year: '2020' ... --- _id: '8721' abstract: - lang: eng text: Spontaneously arising channels that transport the phytohormone auxin provide positional cues for self-organizing aspects of plant development such as flexible vasculature regeneration or its patterning during leaf venation. The auxin canalization hypothesis proposes a feedback between auxin signaling and transport as the underlying mechanism, but molecular players await discovery. We identified part of the machinery that routes auxin transport. The auxin-regulated receptor CAMEL (Canalization-related Auxin-regulated Malectin-type RLK) together with CANAR (Canalization-related Receptor-like kinase) interact with and phosphorylate PIN auxin transporters. camel and canar mutants are impaired in PIN1 subcellular trafficking and auxin-mediated PIN polarization, which macroscopically manifests as defects in leaf venation and vasculature regeneration after wounding. The CAMEL-CANAR receptor complex is part of the auxin feedback that coordinates polarization of individual cells during auxin canalization. acknowledged_ssus: - _id: Bio - _id: LifeSc acknowledgement: 'We acknowledge M. Glanc and Y. Zhang for providing entryclones; Vienna Biocenter Core Facilities (VBCF) for recombinantprotein production and purification; Vienna Biocenter Massspectrometry Facility, Bioimaging, and Life Science Facilities at IST Austria and Proteomics Core Facility CEITEC for a great assistance.Funding:This project received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (grant agreement 742985) and Austrian Science Fund (FWF): I 3630-B25 to J.F.and by grants from the Austrian Academy of Science through the Gregor Mendel Institute (Y.B.) and the Austrian Agency for International Cooperation in Education and Research (D.D.); the Netherlands Organization for Scientific Research (NWO; VIDI-864.13.001) (W.S.); the Research Foundation–Flanders (FWO;Odysseus II G0D0515N) and a European Research Council grant (ERC; StG TORPEDO; 714055) to B.D.R., B.Y., and E.M.; and the Hertha Firnberg Programme postdoctoral fellowship (T-947) from the FWF Austrian Science Fund to E.S.-L.; J.H. is the recipient of a DOC Fellowship of the Austrian Academy of Sciences at IST Austria.' article_processing_charge: No article_type: original author: - first_name: Jakub full_name: Hajny, Jakub id: 4800CC20-F248-11E8-B48F-1D18A9856A87 last_name: Hajny orcid: 0000-0003-2140-7195 - first_name: Tomas full_name: Prat, Tomas id: 3DA3BFEE-F248-11E8-B48F-1D18A9856A87 last_name: Prat - first_name: N full_name: Rydza, N last_name: Rydza - first_name: Lesia full_name: Rodriguez Solovey, Lesia id: 3922B506-F248-11E8-B48F-1D18A9856A87 last_name: Rodriguez Solovey orcid: 0000-0002-7244-7237 - first_name: Shutang full_name: Tan, Shutang id: 2DE75584-F248-11E8-B48F-1D18A9856A87 last_name: Tan orcid: 0000-0002-0471-8285 - first_name: Inge full_name: Verstraeten, Inge id: 362BF7FE-F248-11E8-B48F-1D18A9856A87 last_name: Verstraeten orcid: 0000-0001-7241-2328 - first_name: David full_name: Domjan, David id: C684CD7A-257E-11EA-9B6F-D8588B4F947F last_name: Domjan orcid: 0000-0003-2267-106X - first_name: E full_name: Mazur, E last_name: Mazur - first_name: E full_name: Smakowska-Luzan, E last_name: Smakowska-Luzan - first_name: W full_name: Smet, W last_name: Smet - first_name: E full_name: Mor, E last_name: Mor - first_name: J full_name: Nolf, J last_name: Nolf - first_name: B full_name: Yang, B last_name: Yang - first_name: W full_name: Grunewald, W last_name: Grunewald - first_name: Gergely full_name: Molnar, Gergely id: 34F1AF46-F248-11E8-B48F-1D18A9856A87 last_name: Molnar - first_name: Y full_name: Belkhadir, Y last_name: Belkhadir - first_name: B full_name: De Rybel, B last_name: De Rybel - first_name: Jiří full_name: Friml, Jiří id: 4159519E-F248-11E8-B48F-1D18A9856A87 last_name: Friml orcid: 0000-0002-8302-7596 citation: ama: Hajny J, Prat T, Rydza N, et al. Receptor kinase module targets PIN-dependent auxin transport during canalization. Science. 2020;370(6516):550-557. doi:10.1126/science.aba3178 apa: Hajny, J., Prat, T., Rydza, N., Rodriguez Solovey, L., Tan, S., Verstraeten, I., … Friml, J. (2020). Receptor kinase module targets PIN-dependent auxin transport during canalization. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.aba3178 chicago: Hajny, Jakub, Tomas Prat, N Rydza, Lesia Rodriguez Solovey, Shutang Tan, Inge Verstraeten, David Domjan, et al. “Receptor Kinase Module Targets PIN-Dependent Auxin Transport during Canalization.” Science. American Association for the Advancement of Science, 2020. https://doi.org/10.1126/science.aba3178. ieee: J. Hajny et al., “Receptor kinase module targets PIN-dependent auxin transport during canalization,” Science, vol. 370, no. 6516. American Association for the Advancement of Science, pp. 550–557, 2020. ista: Hajny J, Prat T, Rydza N, Rodriguez Solovey L, Tan S, Verstraeten I, Domjan D, Mazur E, Smakowska-Luzan E, Smet W, Mor E, Nolf J, Yang B, Grunewald W, Molnar G, Belkhadir Y, De Rybel B, Friml J. 2020. Receptor kinase module targets PIN-dependent auxin transport during canalization. Science. 370(6516), 550–557. mla: Hajny, Jakub, et al. “Receptor Kinase Module Targets PIN-Dependent Auxin Transport during Canalization.” Science, vol. 370, no. 6516, American Association for the Advancement of Science, 2020, pp. 550–57, doi:10.1126/science.aba3178. short: J. Hajny, T. Prat, N. Rydza, L. Rodriguez Solovey, S. Tan, I. Verstraeten, D. Domjan, E. Mazur, E. Smakowska-Luzan, W. Smet, E. Mor, J. Nolf, B. Yang, W. Grunewald, G. Molnar, Y. Belkhadir, B. De Rybel, J. Friml, Science 370 (2020) 550–557. date_created: 2020-11-02T10:04:46Z date_published: 2020-10-30T00:00:00Z date_updated: 2023-09-05T12:02:35Z day: '30' department: - _id: JiFr doi: 10.1126/science.aba3178 ec_funded: 1 external_id: isi: - '000583031800041' pmid: - '33122378' intvolume: ' 370' isi: 1 issue: '6516' language: - iso: eng main_file_link: - open_access: '1' url: https://europepmc.org/article/MED/33122378#free-full-text month: '10' oa: 1 oa_version: Published Version page: 550-557 pmid: 1 project: - _id: 261099A6-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '742985' name: Tracing Evolution of Auxin Transport and Polarity in Plants - _id: 26538374-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: I03630 name: Molecular mechanisms of endocytic cargo recognition in plants - _id: 2699E3D2-B435-11E9-9278-68D0E5697425 grant_number: '25239' name: Cell surface receptor complexes for PIN polarity and auxin-mediated development publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' related_material: link: - description: News on IST Homepage relation: press_release url: https://ist.ac.at/en/news/molecular-compass-for-cell-orientation/ scopus_import: '1' status: public title: Receptor kinase module targets PIN-dependent auxin transport during canalization type: journal_article user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1 volume: 370 year: '2020' ... --- _id: '15152' abstract: - lang: eng text: Transcription factors (TFs) regulate gene expression through chromatin where nucleosomes restrict DNA access. To study how TFs bind nucleosome-occupied motifs, we focused on the reprogramming factors OCT4 and SOX2 in mouse embryonic stem cells. We determined TF engagement throughout a nucleosome at base-pair resolution in vitro, enabling structure determination by cryo–electron microscopy at two preferred positions. Depending on motif location, OCT4 and SOX2 differentially distort nucleosomal DNA. At one position, OCT4-SOX2 removes DNA from histone H2A and histone H3; however, at an inverted motif, the TFs only induce local DNA distortions. OCT4 uses one of its two DNA-binding domains to engage DNA in both structures, reading out a partial motif. These findings explain site-specific nucleosome engagement by the pluripotency factors OCT4 and SOX2, and they reveal how TFs distort nucleosomes to access chromatinized motifs. article_processing_charge: No article_type: original author: - first_name: Alicia Kathleen full_name: Michael, Alicia Kathleen id: 6437c950-2a03-11ee-914d-d6476dd7b75c last_name: Michael orcid: 0000-0002-6080-839X - first_name: Ralph S. full_name: Grand, Ralph S. last_name: Grand - first_name: Luke full_name: Isbel, Luke last_name: Isbel - first_name: Simone full_name: Cavadini, Simone last_name: Cavadini - first_name: Zuzanna full_name: Kozicka, Zuzanna last_name: Kozicka - first_name: Georg full_name: Kempf, Georg last_name: Kempf - first_name: Richard D. full_name: Bunker, Richard D. last_name: Bunker - first_name: Andreas D. full_name: Schenk, Andreas D. last_name: Schenk - first_name: Alexandra full_name: Graff-Meyer, Alexandra last_name: Graff-Meyer - first_name: Ganesh R. full_name: Pathare, Ganesh R. last_name: Pathare - first_name: Joscha full_name: Weiss, Joscha last_name: Weiss - first_name: Syota full_name: Matsumoto, Syota last_name: Matsumoto - first_name: Lukas full_name: Burger, Lukas last_name: Burger - first_name: Dirk full_name: Schübeler, Dirk last_name: Schübeler - first_name: Nicolas H. full_name: Thomä, Nicolas H. last_name: Thomä citation: ama: Michael AK, Grand RS, Isbel L, et al. Mechanisms of OCT4-SOX2 motif readout on nucleosomes. Science. 2020;368(6498):1460-1465. doi:10.1126/science.abb0074 apa: Michael, A. K., Grand, R. S., Isbel, L., Cavadini, S., Kozicka, Z., Kempf, G., … Thomä, N. H. (2020). Mechanisms of OCT4-SOX2 motif readout on nucleosomes. Science. American Association for the Advancement of Science . https://doi.org/10.1126/science.abb0074 chicago: Michael, Alicia K., Ralph S. Grand, Luke Isbel, Simone Cavadini, Zuzanna Kozicka, Georg Kempf, Richard D. Bunker, et al. “Mechanisms of OCT4-SOX2 Motif Readout on Nucleosomes.” Science. American Association for the Advancement of Science , 2020. https://doi.org/10.1126/science.abb0074. ieee: A. K. Michael et al., “Mechanisms of OCT4-SOX2 motif readout on nucleosomes,” Science, vol. 368, no. 6498. American Association for the Advancement of Science , pp. 1460–1465, 2020. ista: Michael AK, Grand RS, Isbel L, Cavadini S, Kozicka Z, Kempf G, Bunker RD, Schenk AD, Graff-Meyer A, Pathare GR, Weiss J, Matsumoto S, Burger L, Schübeler D, Thomä NH. 2020. Mechanisms of OCT4-SOX2 motif readout on nucleosomes. Science. 368(6498), 1460–1465. mla: Michael, Alicia K., et al. “Mechanisms of OCT4-SOX2 Motif Readout on Nucleosomes.” Science, vol. 368, no. 6498, American Association for the Advancement of Science , 2020, pp. 1460–65, doi:10.1126/science.abb0074. short: A.K. Michael, R.S. Grand, L. Isbel, S. Cavadini, Z. Kozicka, G. Kempf, R.D. Bunker, A.D. Schenk, A. Graff-Meyer, G.R. Pathare, J. Weiss, S. Matsumoto, L. Burger, D. Schübeler, N.H. Thomä, Science 368 (2020) 1460–1465. date_created: 2024-03-21T07:54:44Z date_published: 2020-04-23T00:00:00Z date_updated: 2024-03-25T12:29:34Z day: '23' doi: 10.1126/science.abb0074 extern: '1' intvolume: ' 368' issue: '6498' language: - iso: eng month: '04' oa_version: None page: 1460-1465 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: 'American Association for the Advancement of Science ' quality_controlled: '1' scopus_import: '1' status: public title: Mechanisms of OCT4-SOX2 motif readout on nucleosomes type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 368 year: '2020' ... --- _id: '10625' abstract: - lang: eng text: The discovery of superconductivity and exotic insulating phases in twisted bilayer graphene has established this material as a model system of strongly correlated electrons. To achieve superconductivity, the two layers of graphene need to be at a very precise angle with respect to each other. Yankowitz et al. now show that another experimental knob, hydrostatic pressure, can be used to tune the phase diagram of twisted bilayer graphene (see the Perspective by Feldman). Applying pressure increased the coupling between the layers, which shifted the superconducting transition to higher angles and somewhat higher temperatures. acknowledgement: We thank J. Zhu and H. Zhou for experimental assistance and D. Shahar, A. Millis, O. Vafek, M. Zaletel, L. Balents, C. Xu, A. Bernevig, L. Fu, M. Koshino, and P. Moon for helpful discussions. article_processing_charge: No article_type: original author: - first_name: Matthew full_name: Yankowitz, Matthew last_name: Yankowitz - first_name: Shaowen full_name: Chen, Shaowen last_name: Chen - first_name: Hryhoriy full_name: Polshyn, Hryhoriy id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48 last_name: Polshyn orcid: 0000-0001-8223-8896 - first_name: Yuxuan full_name: Zhang, Yuxuan last_name: Zhang - first_name: K. full_name: Watanabe, K. last_name: Watanabe - first_name: T. full_name: Taniguchi, T. last_name: Taniguchi - first_name: David full_name: Graf, David last_name: Graf - first_name: Andrea F. full_name: Young, Andrea F. last_name: Young - first_name: Cory R. full_name: Dean, Cory R. last_name: Dean citation: ama: Yankowitz M, Chen S, Polshyn H, et al. Tuning superconductivity in twisted bilayer graphene. Science. 2019;363(6431):1059-1064. doi:10.1126/science.aav1910 apa: Yankowitz, M., Chen, S., Polshyn, H., Zhang, Y., Watanabe, K., Taniguchi, T., … Dean, C. R. (2019). Tuning superconductivity in twisted bilayer graphene. Science. American Association for the Advancement of Science (AAAS). https://doi.org/10.1126/science.aav1910 chicago: Yankowitz, Matthew, Shaowen Chen, Hryhoriy Polshyn, Yuxuan Zhang, K. Watanabe, T. Taniguchi, David Graf, Andrea F. Young, and Cory R. Dean. “Tuning Superconductivity in Twisted Bilayer Graphene.” Science. American Association for the Advancement of Science (AAAS), 2019. https://doi.org/10.1126/science.aav1910. ieee: M. Yankowitz et al., “Tuning superconductivity in twisted bilayer graphene,” Science, vol. 363, no. 6431. American Association for the Advancement of Science (AAAS), pp. 1059–1064, 2019. ista: Yankowitz M, Chen S, Polshyn H, Zhang Y, Watanabe K, Taniguchi T, Graf D, Young AF, Dean CR. 2019. Tuning superconductivity in twisted bilayer graphene. Science. 363(6431), 1059–1064. mla: Yankowitz, Matthew, et al. “Tuning Superconductivity in Twisted Bilayer Graphene.” Science, vol. 363, no. 6431, American Association for the Advancement of Science (AAAS), 2019, pp. 1059–64, doi:10.1126/science.aav1910. short: M. Yankowitz, S. Chen, H. Polshyn, Y. Zhang, K. Watanabe, T. Taniguchi, D. Graf, A.F. Young, C.R. Dean, Science 363 (2019) 1059–1064. date_created: 2022-01-14T12:14:58Z date_published: 2019-01-24T00:00:00Z date_updated: 2022-01-14T13:48:32Z day: '24' doi: 10.1126/science.aav1910 extern: '1' external_id: arxiv: - '1808.07865' pmid: - '30679385 ' intvolume: ' 363' issue: '6431' keyword: - multidisciplinary language: - iso: eng main_file_link: - open_access: '1' url: https://arxiv.org/abs/1808.07865 month: '01' oa: 1 oa_version: Preprint page: 1059-1064 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science (AAAS) quality_controlled: '1' scopus_import: '1' status: public title: Tuning superconductivity in twisted bilayer graphene type: journal_article user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9 volume: 363 year: '2019' ... --- _id: '10619' abstract: - lang: eng text: The quantum anomalous Hall (QAH) effect combines topology and magnetism to produce precisely quantized Hall resistance at zero magnetic field. We report the observation of a QAH effect in twisted bilayer graphene aligned to hexagonal boron nitride. The effect is driven by intrinsic strong interactions, which polarize the electrons into a single spin- and valley-resolved moiré miniband with Chern number C = 1. In contrast to magnetically doped systems, the measured transport energy gap is larger than the Curie temperature for magnetic ordering, and quantization to within 0.1% of the von Klitzing constant persists to temperatures of several kelvin at zero magnetic field. Electrical currents as small as 1 nanoampere controllably switch the magnetic order between states of opposite polarization, forming an electrically rewritable magnetic memory. acknowledgement: The authors acknowledge discussions with A. Macdonald, Y. Saito, and M. Zaletel. article_processing_charge: No article_type: original author: - first_name: M. full_name: Serlin, M. last_name: Serlin - first_name: C. L. full_name: Tschirhart, C. L. last_name: Tschirhart - first_name: Hryhoriy full_name: Polshyn, Hryhoriy id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48 last_name: Polshyn orcid: 0000-0001-8223-8896 - first_name: Y. full_name: Zhang, Y. last_name: Zhang - first_name: J. full_name: Zhu, J. last_name: Zhu - first_name: K. full_name: Watanabe, K. last_name: Watanabe - first_name: T. full_name: Taniguchi, T. last_name: Taniguchi - first_name: L. full_name: Balents, L. last_name: Balents - first_name: A. F. full_name: Young, A. F. last_name: Young citation: ama: Serlin M, Tschirhart CL, Polshyn H, et al. Intrinsic quantized anomalous Hall effect in a moiré heterostructure. Science. 2019;367(6480):900-903. doi:10.1126/science.aay5533 apa: Serlin, M., Tschirhart, C. L., Polshyn, H., Zhang, Y., Zhu, J., Watanabe, K., … Young, A. F. (2019). Intrinsic quantized anomalous Hall effect in a moiré heterostructure. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.aay5533 chicago: Serlin, M., C. L. Tschirhart, Hryhoriy Polshyn, Y. Zhang, J. Zhu, K. Watanabe, T. Taniguchi, L. Balents, and A. F. Young. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure.” Science. American Association for the Advancement of Science, 2019. https://doi.org/10.1126/science.aay5533. ieee: M. Serlin et al., “Intrinsic quantized anomalous Hall effect in a moiré heterostructure,” Science, vol. 367, no. 6480. American Association for the Advancement of Science, pp. 900–903, 2019. ista: Serlin M, Tschirhart CL, Polshyn H, Zhang Y, Zhu J, Watanabe K, Taniguchi T, Balents L, Young AF. 2019. Intrinsic quantized anomalous Hall effect in a moiré heterostructure. Science. 367(6480), 900–903. mla: Serlin, M., et al. “Intrinsic Quantized Anomalous Hall Effect in a Moiré Heterostructure.” Science, vol. 367, no. 6480, American Association for the Advancement of Science, 2019, pp. 900–03, doi:10.1126/science.aay5533. short: M. Serlin, C.L. Tschirhart, H. Polshyn, Y. Zhang, J. Zhu, K. Watanabe, T. Taniguchi, L. Balents, A.F. Young, Science 367 (2019) 900–903. date_created: 2022-01-13T14:21:32Z date_published: 2019-12-19T00:00:00Z date_updated: 2023-02-21T16:00:09Z day: '19' doi: 10.1126/science.aay5533 extern: '1' external_id: arxiv: - '1907.00261' pmid: - '31857492' intvolume: ' 367' issue: '6480' keyword: - multidisciplinary language: - iso: eng main_file_link: - open_access: '1' url: https://arxiv.org/abs/1907.00261 month: '12' oa: 1 oa_version: Preprint page: 900-903 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' related_material: record: - id: '10697' relation: other status: public - id: '10698' relation: other status: public - id: '10699' relation: other status: public scopus_import: '1' status: public title: Intrinsic quantized anomalous Hall effect in a moiré heterostructure type: journal_article user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9 volume: 367 year: '2019' ... --- _id: '7082' abstract: - lang: eng text: Although crystals of strongly correlated metals exhibit a diverse set of electronic ground states, few approaches exist for spatially modulating their properties. In this study, we demonstrate disorder-free control, on the micrometer scale, over the superconducting state in samples of the heavy-fermion superconductor CeIrIn5. We pattern crystals by focused ion beam milling to tailor the boundary conditions for the elastic deformation upon thermal contraction during cooling. The resulting nonuniform strain fields induce complex patterns of superconductivity, owing to the strong dependence of the transition temperature on the strength and direction of strain. These results showcase a generic approach to manipulating electronic order on micrometer length scales in strongly correlated matter without compromising the cleanliness, stoichiometry, or mean free path. article_processing_charge: No article_type: original author: - first_name: Maja D. full_name: Bachmann, Maja D. last_name: Bachmann - first_name: G. M. full_name: Ferguson, G. M. last_name: Ferguson - first_name: Florian full_name: Theuss, Florian last_name: Theuss - first_name: Tobias full_name: Meng, Tobias last_name: Meng - first_name: Carsten full_name: Putzke, Carsten last_name: Putzke - first_name: Toni full_name: Helm, Toni last_name: Helm - first_name: K. R. full_name: Shirer, K. R. last_name: Shirer - first_name: You-Sheng full_name: Li, You-Sheng last_name: Li - first_name: Kimberly A full_name: Modic, Kimberly A id: 13C26AC0-EB69-11E9-87C6-5F3BE6697425 last_name: Modic orcid: 0000-0001-9760-3147 - first_name: Michael full_name: Nicklas, Michael last_name: Nicklas - first_name: Markus full_name: König, Markus last_name: König - first_name: D. full_name: Low, D. last_name: Low - first_name: Sayak full_name: Ghosh, Sayak last_name: Ghosh - first_name: Andrew P. full_name: Mackenzie, Andrew P. last_name: Mackenzie - first_name: Frank full_name: Arnold, Frank last_name: Arnold - first_name: Elena full_name: Hassinger, Elena last_name: Hassinger - first_name: Ross D. full_name: McDonald, Ross D. last_name: McDonald - first_name: Laurel E. full_name: Winter, Laurel E. last_name: Winter - first_name: Eric D. full_name: Bauer, Eric D. last_name: Bauer - first_name: Filip full_name: Ronning, Filip last_name: Ronning - first_name: B. J. full_name: Ramshaw, B. J. last_name: Ramshaw - first_name: Katja C. full_name: Nowack, Katja C. last_name: Nowack - first_name: Philip J. W. full_name: Moll, Philip J. W. last_name: Moll citation: ama: Bachmann MD, Ferguson GM, Theuss F, et al. Spatial control of heavy-fermion superconductivity in CeIrIn5. Science. 2019;366(6462):221-226. doi:10.1126/science.aao6640 apa: Bachmann, M. D., Ferguson, G. M., Theuss, F., Meng, T., Putzke, C., Helm, T., … Moll, P. J. W. (2019). Spatial control of heavy-fermion superconductivity in CeIrIn5. Science. AAAS. https://doi.org/10.1126/science.aao6640 chicago: Bachmann, Maja D., G. M. Ferguson, Florian Theuss, Tobias Meng, Carsten Putzke, Toni Helm, K. R. Shirer, et al. “Spatial Control of Heavy-Fermion Superconductivity in CeIrIn5.” Science. AAAS, 2019. https://doi.org/10.1126/science.aao6640. ieee: M. D. Bachmann et al., “Spatial control of heavy-fermion superconductivity in CeIrIn5,” Science, vol. 366, no. 6462. AAAS, pp. 221–226, 2019. ista: Bachmann MD, Ferguson GM, Theuss F, Meng T, Putzke C, Helm T, Shirer KR, Li Y-S, Modic KA, Nicklas M, König M, Low D, Ghosh S, Mackenzie AP, Arnold F, Hassinger E, McDonald RD, Winter LE, Bauer ED, Ronning F, Ramshaw BJ, Nowack KC, Moll PJW. 2019. Spatial control of heavy-fermion superconductivity in CeIrIn5. Science. 366(6462), 221–226. mla: Bachmann, Maja D., et al. “Spatial Control of Heavy-Fermion Superconductivity in CeIrIn5.” Science, vol. 366, no. 6462, AAAS, 2019, pp. 221–26, doi:10.1126/science.aao6640. short: M.D. Bachmann, G.M. Ferguson, F. Theuss, T. Meng, C. Putzke, T. Helm, K.R. Shirer, Y.-S. Li, K.A. Modic, M. Nicklas, M. König, D. Low, S. Ghosh, A.P. Mackenzie, F. Arnold, E. Hassinger, R.D. McDonald, L.E. Winter, E.D. Bauer, F. Ronning, B.J. Ramshaw, K.C. Nowack, P.J.W. Moll, Science 366 (2019) 221–226. date_created: 2019-11-19T13:55:58Z date_published: 2019-10-11T00:00:00Z date_updated: 2021-01-12T08:11:46Z day: '11' doi: 10.1126/science.aao6640 extern: '1' intvolume: ' 366' issue: '6462' language: - iso: eng month: '10' oa_version: None page: 221-226 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: AAAS quality_controlled: '1' status: public title: Spatial control of heavy-fermion superconductivity in CeIrIn5 type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 366 year: '2019' ... --- _id: '6859' abstract: - lang: eng text: V (vacuolar)/A (archaeal)-type adenosine triphosphatases (ATPases), found in archaeaand eubacteria, couple ATP hydrolysis or synthesis to proton translocation across theplasma membrane using the rotary-catalysis mechanism. They belong to the V-typeATPase family, which differs from the mitochondrial/chloroplast F-type ATP synthasesin overall architecture. We solved cryo–electron microscopy structures of the intactThermus thermophilusV/A-ATPase, reconstituted into lipid nanodiscs, in three rotationalstates and two substates. These structures indicate substantial flexibility betweenV1and Voin a working enzyme, which results from mechanical competition between centralshaft rotation and resistance from the peripheral stalks. We also describedetails of adenosine diphosphate inhibition release, V1-Votorque transmission, andproton translocation, which are relevant for the entire V-type ATPase family. acknowledged_ssus: - _id: ScienComp article_number: eaaw9144 article_processing_charge: No author: - first_name: Long full_name: Zhou, Long id: 3E751364-F248-11E8-B48F-1D18A9856A87 last_name: Zhou orcid: 0000-0002-1864-8951 - first_name: Leonid A full_name: Sazanov, Leonid A id: 338D39FE-F248-11E8-B48F-1D18A9856A87 last_name: Sazanov orcid: 0000-0002-0977-7989 citation: ama: Zhou L, Sazanov LA. Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase. Science. 2019;365(6455). doi:10.1126/science.aaw9144 apa: Zhou, L., & Sazanov, L. A. (2019). Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase. Science. AAAS. https://doi.org/10.1126/science.aaw9144 chicago: Zhou, Long, and Leonid A Sazanov. “Structure and Conformational Plasticity of the Intact Thermus Thermophilus V/A-Type ATPase.” Science. AAAS, 2019. https://doi.org/10.1126/science.aaw9144. ieee: L. Zhou and L. A. Sazanov, “Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase,” Science, vol. 365, no. 6455. AAAS, 2019. ista: Zhou L, Sazanov LA. 2019. Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase. Science. 365(6455), eaaw9144. mla: Zhou, Long, and Leonid A. Sazanov. “Structure and Conformational Plasticity of the Intact Thermus Thermophilus V/A-Type ATPase.” Science, vol. 365, no. 6455, eaaw9144, AAAS, 2019, doi:10.1126/science.aaw9144. short: L. Zhou, L.A. Sazanov, Science 365 (2019). date_created: 2019-09-07T19:04:45Z date_published: 2019-08-23T00:00:00Z date_updated: 2023-08-29T07:52:02Z day: '23' department: - _id: LeSa doi: 10.1126/science.aaw9144 external_id: isi: - '000482464000043' pmid: - '31439765' intvolume: ' 365' isi: 1 issue: '6455' language: - iso: eng month: '08' oa_version: None pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: AAAS quality_controlled: '1' related_material: link: - description: News on IST Website relation: press_release url: https://ist.ac.at/en/news/structure-of-protein-nano-turbine-revealed/ scopus_import: '1' status: public title: Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase type: journal_article user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8 volume: 365 year: '2019' ... --- _id: '6455' abstract: - lang: eng text: During corticogenesis, distinct subtypes of neurons are sequentially born from ventricular zone progenitors. How these cells are molecularly temporally patterned is poorly understood. We used single-cell RNA sequencing at high temporal resolution to trace the lineage of the molecular identities of successive generations of apical progenitors (APs) and their daughter neurons in mouse embryos. We identified a core set of evolutionarily conserved, temporally patterned genes that drive APs from internally driven to more exteroceptive states. We found that the Polycomb repressor complex 2 (PRC2) epigenetically regulates AP temporal progression. Embryonic age–dependent AP molecular states are transmitted to their progeny as successive ground states, onto which essentially conserved early postmitotic differentiation programs are applied, and are complemented by later-occurring environment-dependent signals. Thus, epigenetically regulated temporal molecular birthmarks present in progenitors act in their postmitotic progeny to seed adult neuronal diversity. article_number: eaav2522 article_processing_charge: No article_type: original author: - first_name: L full_name: Telley, L last_name: Telley - first_name: G full_name: Agirman, G last_name: Agirman - first_name: J full_name: Prados, J last_name: Prados - first_name: Nicole full_name: Amberg, Nicole id: 4CD6AAC6-F248-11E8-B48F-1D18A9856A87 last_name: Amberg orcid: 0000-0002-3183-8207 - first_name: S full_name: Fièvre, S last_name: Fièvre - first_name: P full_name: Oberst, P last_name: Oberst - first_name: G full_name: Bartolini, G last_name: Bartolini - first_name: I full_name: Vitali, I last_name: Vitali - first_name: C full_name: Cadilhac, C last_name: Cadilhac - first_name: Simon full_name: Hippenmeyer, Simon id: 37B36620-F248-11E8-B48F-1D18A9856A87 last_name: Hippenmeyer orcid: 0000-0003-2279-1061 - first_name: L full_name: Nguyen, L last_name: Nguyen - first_name: A full_name: Dayer, A last_name: Dayer - first_name: D full_name: Jabaudon, D last_name: Jabaudon citation: ama: Telley L, Agirman G, Prados J, et al. Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex. Science. 2019;364(6440). doi:10.1126/science.aav2522 apa: Telley, L., Agirman, G., Prados, J., Amberg, N., Fièvre, S., Oberst, P., … Jabaudon, D. (2019). Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex. Science. AAAS. https://doi.org/10.1126/science.aav2522 chicago: Telley, L, G Agirman, J Prados, Nicole Amberg, S Fièvre, P Oberst, G Bartolini, et al. “Temporal Patterning of Apical Progenitors and Their Daughter Neurons in the Developing Neocortex.” Science. AAAS, 2019. https://doi.org/10.1126/science.aav2522. ieee: L. Telley et al., “Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex,” Science, vol. 364, no. 6440. AAAS, 2019. ista: Telley L, Agirman G, Prados J, Amberg N, Fièvre S, Oberst P, Bartolini G, Vitali I, Cadilhac C, Hippenmeyer S, Nguyen L, Dayer A, Jabaudon D. 2019. Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex. Science. 364(6440), eaav2522. mla: Telley, L., et al. “Temporal Patterning of Apical Progenitors and Their Daughter Neurons in the Developing Neocortex.” Science, vol. 364, no. 6440, eaav2522, AAAS, 2019, doi:10.1126/science.aav2522. short: L. Telley, G. Agirman, J. Prados, N. Amberg, S. Fièvre, P. Oberst, G. Bartolini, I. Vitali, C. Cadilhac, S. Hippenmeyer, L. Nguyen, A. Dayer, D. Jabaudon, Science 364 (2019). date_created: 2019-05-14T13:07:47Z date_published: 2019-05-10T00:00:00Z date_updated: 2023-09-05T11:51:09Z day: '10' department: - _id: SiHi doi: 10.1126/science.aav2522 ec_funded: 1 external_id: isi: - '000467631800034' pmid: - '31073041' intvolume: ' 364' isi: 1 issue: '6440' language: - iso: eng main_file_link: - open_access: '1' url: https://orbi.uliege.be/bitstream/2268/239604/1/Telley_Agirman_Science2019.pdf month: '05' oa: 1 oa_version: Published Version pmid: 1 project: - _id: 260018B0-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '725780' name: Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development - _id: 268F8446-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: T0101031 name: Role of Eed in neural stem cell lineage progression publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: AAAS quality_controlled: '1' related_material: link: - description: News on IST Homepage relation: press_release url: https://ist.ac.at/en/news/how-to-generate-a-brain-of-correct-size-and-composition/ scopus_import: '1' status: public title: Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex type: journal_article user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1 volume: 364 year: '2019' ... --- _id: '6194' abstract: - lang: eng text: Grid cells with their rigid hexagonal firing fields are thought to provide an invariant metric to the hippocampal cognitive map, yet environmental geometrical features have recently been shown to distort the grid structure. Given that the hippocampal role goes beyond space, we tested the influence of nonspatial information on the grid organization. We trained rats to daily learn three new reward locations on a cheeseboard maze while recording from the medial entorhinal cortex and the hippocampal CA1 region. Many grid fields moved toward goal location, leading to long-lasting deformations of the entorhinal map. Therefore, distortions in the grid structure contribute to goal representation during both learning and recall, which demonstrates that grid cells participate in mnemonic coding and do not merely provide a simple metric of space. article_processing_charge: No article_type: original author: - first_name: Charlotte N. full_name: Boccara, Charlotte N. id: 3FC06552-F248-11E8-B48F-1D18A9856A87 last_name: Boccara orcid: 0000-0001-7237-5109 - first_name: Michele full_name: Nardin, Michele id: 30BD0376-F248-11E8-B48F-1D18A9856A87 last_name: Nardin orcid: 0000-0001-8849-6570 - first_name: Federico full_name: Stella, Federico id: 39AF1E74-F248-11E8-B48F-1D18A9856A87 last_name: Stella orcid: 0000-0001-9439-3148 - first_name: Joseph full_name: O'Neill, Joseph id: 426376DC-F248-11E8-B48F-1D18A9856A87 last_name: O'Neill - first_name: Jozsef L full_name: Csicsvari, Jozsef L id: 3FA14672-F248-11E8-B48F-1D18A9856A87 last_name: Csicsvari orcid: 0000-0002-5193-4036 citation: ama: Boccara CN, Nardin M, Stella F, O’Neill J, Csicsvari JL. The entorhinal cognitive map is attracted to goals. Science. 2019;363(6434):1443-1447. doi:10.1126/science.aav4837 apa: Boccara, C. N., Nardin, M., Stella, F., O’Neill, J., & Csicsvari, J. L. (2019). The entorhinal cognitive map is attracted to goals. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.aav4837 chicago: Boccara, Charlotte N., Michele Nardin, Federico Stella, Joseph O’Neill, and Jozsef L Csicsvari. “The Entorhinal Cognitive Map Is Attracted to Goals.” Science. American Association for the Advancement of Science, 2019. https://doi.org/10.1126/science.aav4837. ieee: C. N. Boccara, M. Nardin, F. Stella, J. O’Neill, and J. L. Csicsvari, “The entorhinal cognitive map is attracted to goals,” Science, vol. 363, no. 6434. American Association for the Advancement of Science, pp. 1443–1447, 2019. ista: Boccara CN, Nardin M, Stella F, O’Neill J, Csicsvari JL. 2019. The entorhinal cognitive map is attracted to goals. Science. 363(6434), 1443–1447. mla: Boccara, Charlotte N., et al. “The Entorhinal Cognitive Map Is Attracted to Goals.” Science, vol. 363, no. 6434, American Association for the Advancement of Science, 2019, pp. 1443–47, doi:10.1126/science.aav4837. short: C.N. Boccara, M. Nardin, F. Stella, J. O’Neill, J.L. Csicsvari, Science 363 (2019) 1443–1447. date_created: 2019-04-04T08:39:30Z date_published: 2019-03-29T00:00:00Z date_updated: 2024-03-28T23:30:16Z day: '29' ddc: - '570' department: - _id: JoCs doi: 10.1126/science.aav4837 ec_funded: 1 external_id: isi: - '000462738000034' file: - access_level: open_access checksum: 5e6b16742cde10a560cfaf2130764da1 content_type: application/pdf creator: dernst date_created: 2020-05-14T09:11:10Z date_updated: 2020-07-14T12:47:23Z file_id: '7826' file_name: 2019_Science_Boccara.pdf file_size: 9045923 relation: main_file file_date_updated: 2020-07-14T12:47:23Z has_accepted_license: '1' intvolume: ' 363' isi: 1 issue: '6434' language: - iso: eng month: '03' oa: 1 oa_version: Submitted Version page: 1443-1447 project: - _id: 257A4776-B435-11E9-9278-68D0E5697425 call_identifier: FP7 grant_number: '281511' name: Memory-related information processing in neuronal circuits of the hippocampus and entorhinal cortex - _id: 2564DBCA-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '665385' name: International IST Doctoral Program publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' related_material: link: - description: News on IST Homepage relation: press_release url: https://ist.ac.at/en/news/grid-cells-create-treasure-map-in-rat-brain/ record: - id: '6062' relation: popular_science status: public - id: '11932' relation: dissertation_contains status: public scopus_import: '1' status: public title: The entorhinal cognitive map is attracted to goals type: journal_article user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1 volume: 363 year: '2019' ... --- _id: '7060' abstract: - lang: eng text: The anomalous metallic state in the high-temperature superconducting cuprates is masked by superconductivity near a quantum critical point. Applying high magnetic fields to suppress superconductivity has enabled detailed studies of the normal state, yet the direct effect of strong magnetic fields on the metallic state is poorly understood. We report the high-field magnetoresistance of thin-film La2–xSrxCuO4 cuprate in the vicinity of the critical doping, 0.161 ≤ p ≤ 0.190. We find that the metallic state exposed by suppressing superconductivity is characterized by magnetoresistance that is linear in magnetic fields up to 80 tesla. The magnitude of the linear-in-field resistivity mirrors the magnitude and doping evolution of the well-known linear-in-temperature resistivity that has been associated with quantum criticality in high-temperature superconductors. article_processing_charge: No article_type: original author: - first_name: P. full_name: Giraldo-Gallo, P. last_name: Giraldo-Gallo - first_name: J. A. full_name: Galvis, J. A. last_name: Galvis - first_name: Z. full_name: Stegen, Z. last_name: Stegen - first_name: Kimberly A full_name: Modic, Kimberly A id: 13C26AC0-EB69-11E9-87C6-5F3BE6697425 last_name: Modic orcid: 0000-0001-9760-3147 - first_name: F. F. full_name: Balakirev, F. F. last_name: Balakirev - first_name: J. B. full_name: Betts, J. B. last_name: Betts - first_name: X. full_name: Lian, X. last_name: Lian - first_name: C. full_name: Moir, C. last_name: Moir - first_name: S. C. full_name: Riggs, S. C. last_name: Riggs - first_name: J. full_name: Wu, J. last_name: Wu - first_name: A. T. full_name: Bollinger, A. T. last_name: Bollinger - first_name: X. full_name: He, X. last_name: He - first_name: I. full_name: Božović, I. last_name: Božović - first_name: B. J. full_name: Ramshaw, B. J. last_name: Ramshaw - first_name: R. D. full_name: McDonald, R. D. last_name: McDonald - first_name: G. S. full_name: Boebinger, G. S. last_name: Boebinger - first_name: A. full_name: Shekhter, A. last_name: Shekhter citation: ama: Giraldo-Gallo P, Galvis JA, Stegen Z, et al. Scale-invariant magnetoresistance in a cuprate superconductor. Science. 2018;361(6401):479-481. doi:10.1126/science.aan3178 apa: Giraldo-Gallo, P., Galvis, J. A., Stegen, Z., Modic, K. A., Balakirev, F. F., Betts, J. B., … Shekhter, A. (2018). Scale-invariant magnetoresistance in a cuprate superconductor. Science. AAAS. https://doi.org/10.1126/science.aan3178 chicago: Giraldo-Gallo, P., J. A. Galvis, Z. Stegen, Kimberly A Modic, F. F. Balakirev, J. B. Betts, X. Lian, et al. “Scale-Invariant Magnetoresistance in a Cuprate Superconductor.” Science. AAAS, 2018. https://doi.org/10.1126/science.aan3178. ieee: P. Giraldo-Gallo et al., “Scale-invariant magnetoresistance in a cuprate superconductor,” Science, vol. 361, no. 6401. AAAS, pp. 479–481, 2018. ista: Giraldo-Gallo P, Galvis JA, Stegen Z, Modic KA, Balakirev FF, Betts JB, Lian X, Moir C, Riggs SC, Wu J, Bollinger AT, He X, Božović I, Ramshaw BJ, McDonald RD, Boebinger GS, Shekhter A. 2018. Scale-invariant magnetoresistance in a cuprate superconductor. Science. 361(6401), 479–481. mla: Giraldo-Gallo, P., et al. “Scale-Invariant Magnetoresistance in a Cuprate Superconductor.” Science, vol. 361, no. 6401, AAAS, 2018, pp. 479–81, doi:10.1126/science.aan3178. short: P. Giraldo-Gallo, J.A. Galvis, Z. Stegen, K.A. Modic, F.F. Balakirev, J.B. Betts, X. Lian, C. Moir, S.C. Riggs, J. Wu, A.T. Bollinger, X. He, I. Božović, B.J. Ramshaw, R.D. McDonald, G.S. Boebinger, A. Shekhter, Science 361 (2018) 479–481. date_created: 2019-11-19T13:03:16Z date_published: 2018-08-03T00:00:00Z date_updated: 2021-01-12T08:11:37Z day: '03' doi: 10.1126/science.aan3178 extern: '1' intvolume: ' 361' issue: '6401' language: - iso: eng month: '08' oa_version: None page: 479-481 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: AAAS quality_controlled: '1' status: public title: Scale-invariant magnetoresistance in a cuprate superconductor type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 361 year: '2018' ... --- _id: '7718' abstract: - lang: eng text: Flores Island, Indonesia, was inhabited by the small-bodied hominin species Homo floresiensis, which has an unknown evolutionary relationship to modern humans. This island is also home to an extant human pygmy population. Here we describe genome-scale single-nucleotide polymorphism data and whole-genome sequences from a contemporary human pygmy population living on Flores near the cave where H. floresiensis was found. The genomes of Flores pygmies reveal a complex history of admixture with Denisovans and Neanderthals but no evidence for gene flow with other archaic hominins. Modern individuals bear the signatures of recent positive selection encompassing the FADS (fatty acid desaturase) gene cluster, likely related to diet, and polygenic selection acting on standing variation that contributed to their short-stature phenotype. Thus, multiple independent instances of hominin insular dwarfism occurred on Flores. article_processing_charge: No article_type: original author: - first_name: Serena full_name: Tucci, Serena last_name: Tucci - first_name: Samuel H. full_name: Vohr, Samuel H. last_name: Vohr - first_name: Rajiv C. full_name: McCoy, Rajiv C. last_name: McCoy - first_name: Benjamin full_name: Vernot, Benjamin last_name: Vernot - first_name: Matthew Richard full_name: Robinson, Matthew Richard id: E5D42276-F5DA-11E9-8E24-6303E6697425 last_name: Robinson orcid: 0000-0001-8982-8813 - first_name: Chiara full_name: Barbieri, Chiara last_name: Barbieri - first_name: Brad J. full_name: Nelson, Brad J. last_name: Nelson - first_name: Wenqing full_name: Fu, Wenqing last_name: Fu - first_name: Gludhug A. full_name: Purnomo, Gludhug A. last_name: Purnomo - first_name: Herawati full_name: Sudoyo, Herawati last_name: Sudoyo - first_name: Evan E. full_name: Eichler, Evan E. last_name: Eichler - first_name: Guido full_name: Barbujani, Guido last_name: Barbujani - first_name: Peter M. full_name: Visscher, Peter M. last_name: Visscher - first_name: Joshua M. full_name: Akey, Joshua M. last_name: Akey - first_name: Richard E. full_name: Green, Richard E. last_name: Green citation: ama: Tucci S, Vohr SH, McCoy RC, et al. Evolutionary history and adaptation of a human pygmy population of Flores Island, Indonesia. Science. 2018;361(6401):511-516. doi:10.1126/science.aar8486 apa: Tucci, S., Vohr, S. H., McCoy, R. C., Vernot, B., Robinson, M. R., Barbieri, C., … Green, R. E. (2018). Evolutionary history and adaptation of a human pygmy population of Flores Island, Indonesia. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.aar8486 chicago: Tucci, Serena, Samuel H. Vohr, Rajiv C. McCoy, Benjamin Vernot, Matthew Richard Robinson, Chiara Barbieri, Brad J. Nelson, et al. “Evolutionary History and Adaptation of a Human Pygmy Population of Flores Island, Indonesia.” Science. American Association for the Advancement of Science, 2018. https://doi.org/10.1126/science.aar8486. ieee: S. Tucci et al., “Evolutionary history and adaptation of a human pygmy population of Flores Island, Indonesia,” Science, vol. 361, no. 6401. American Association for the Advancement of Science, pp. 511–516, 2018. ista: Tucci S, Vohr SH, McCoy RC, Vernot B, Robinson MR, Barbieri C, Nelson BJ, Fu W, Purnomo GA, Sudoyo H, Eichler EE, Barbujani G, Visscher PM, Akey JM, Green RE. 2018. Evolutionary history and adaptation of a human pygmy population of Flores Island, Indonesia. Science. 361(6401), 511–516. mla: Tucci, Serena, et al. “Evolutionary History and Adaptation of a Human Pygmy Population of Flores Island, Indonesia.” Science, vol. 361, no. 6401, American Association for the Advancement of Science, 2018, pp. 511–16, doi:10.1126/science.aar8486. short: S. Tucci, S.H. Vohr, R.C. McCoy, B. Vernot, M.R. Robinson, C. Barbieri, B.J. Nelson, W. Fu, G.A. Purnomo, H. Sudoyo, E.E. Eichler, G. Barbujani, P.M. Visscher, J.M. Akey, R.E. Green, Science 361 (2018) 511–516. date_created: 2020-04-30T10:43:24Z date_published: 2018-08-03T00:00:00Z date_updated: 2021-01-12T08:15:04Z day: '03' doi: 10.1126/science.aar8486 extern: '1' external_id: pmid: - '30072539' intvolume: ' 361' issue: '6401' language: - iso: eng month: '08' oa_version: None page: 511-516 pmid: 1 publication: Science publication_identifier: issn: - 0036-8075 - 1095-9203 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' status: public title: Evolutionary history and adaptation of a human pygmy population of Flores Island, Indonesia type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 361 year: '2018' ... --- _id: '5767' abstract: - lang: eng text: 'Cuprate superconductors have long been thought of as having strong electronic correlations but negligible spin-orbit coupling. Using spin- and angle-resolved photoemission spectroscopy, we discovered that one of the most studied cuprate superconductors, Bi2212, has a nontrivial spin texture with a spin-momentum locking that circles the Brillouin zone center and a spin-layer locking that allows states of opposite spin to be localized in different parts of the unit cell. Our findings pose challenges for the vast majority of models of cuprates, such as the Hubbard model and its variants, where spin-orbit interaction has been mostly neglected, and open the intriguing question of how the high-temperature superconducting state emerges in the presence of this nontrivial spin texture. ' acknowledgement: ' M.S. was supported by the Gordon and Betty Moore Foundation s EPiQS Initiative through grant GBMF4307' article_processing_charge: No article_type: original author: - first_name: Kenneth full_name: Gotlieb, Kenneth last_name: Gotlieb - first_name: Chiu-Yun full_name: Lin, Chiu-Yun last_name: Lin - first_name: Maksym full_name: Serbyn, Maksym id: 47809E7E-F248-11E8-B48F-1D18A9856A87 last_name: Serbyn orcid: 0000-0002-2399-5827 - first_name: Wentao full_name: Zhang, Wentao last_name: Zhang - first_name: Christopher L. full_name: Smallwood, Christopher L. last_name: Smallwood - first_name: Christopher full_name: Jozwiak, Christopher last_name: Jozwiak - first_name: Hiroshi full_name: Eisaki, Hiroshi last_name: Eisaki - first_name: Zahid full_name: Hussain, Zahid last_name: Hussain - first_name: Ashvin full_name: Vishwanath, Ashvin last_name: Vishwanath - first_name: Alessandra full_name: Lanzara, Alessandra last_name: Lanzara citation: ama: Gotlieb K, Lin C-Y, Serbyn M, et al. Revealing hidden spin-momentum locking in a high-temperature cuprate superconductor. Science. 2018;362(6420):1271-1275. doi:10.1126/science.aao0980 apa: Gotlieb, K., Lin, C.-Y., Serbyn, M., Zhang, W., Smallwood, C. L., Jozwiak, C., … Lanzara, A. (2018). Revealing hidden spin-momentum locking in a high-temperature cuprate superconductor. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.aao0980 chicago: Gotlieb, Kenneth, Chiu-Yun Lin, Maksym Serbyn, Wentao Zhang, Christopher L. Smallwood, Christopher Jozwiak, Hiroshi Eisaki, Zahid Hussain, Ashvin Vishwanath, and Alessandra Lanzara. “Revealing Hidden Spin-Momentum Locking in a High-Temperature Cuprate Superconductor.” Science. American Association for the Advancement of Science, 2018. https://doi.org/10.1126/science.aao0980. ieee: K. Gotlieb et al., “Revealing hidden spin-momentum locking in a high-temperature cuprate superconductor,” Science, vol. 362, no. 6420. American Association for the Advancement of Science, pp. 1271–1275, 2018. ista: Gotlieb K, Lin C-Y, Serbyn M, Zhang W, Smallwood CL, Jozwiak C, Eisaki H, Hussain Z, Vishwanath A, Lanzara A. 2018. Revealing hidden spin-momentum locking in a high-temperature cuprate superconductor. Science. 362(6420), 1271–1275. mla: Gotlieb, Kenneth, et al. “Revealing Hidden Spin-Momentum Locking in a High-Temperature Cuprate Superconductor.” Science, vol. 362, no. 6420, American Association for the Advancement of Science, 2018, pp. 1271–75, doi:10.1126/science.aao0980. short: K. Gotlieb, C.-Y. Lin, M. Serbyn, W. Zhang, C.L. Smallwood, C. Jozwiak, H. Eisaki, Z. Hussain, A. Vishwanath, A. Lanzara, Science 362 (2018) 1271–1275. date_created: 2018-12-19T14:53:50Z date_published: 2018-12-14T00:00:00Z date_updated: 2023-09-18T08:11:56Z day: '14' department: - _id: MaSe doi: 10.1126/science.aao0980 external_id: isi: - '000452994400048' intvolume: ' 362' isi: 1 issue: '6420' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1126/science.aao0980 month: '12' oa: 1 oa_version: Published Version page: 1271-1275 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Revealing hidden spin-momentum locking in a high-temperature cuprate superconductor type: journal_article user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1 volume: 362 year: '2018' ... --- _id: '13381' abstract: - lang: eng text: Self-assembly of inorganic nanoparticles has been used to prepare hundreds of different colloidal crystals, but almost invariably with the restriction that the particles must be densely packed. Here, we show that non–close-packed nanoparticle arrays can be fabricated through the selective removal of one of two components comprising binary nanoparticle superlattices. First, a variety of binary nanoparticle superlattices were prepared at the liquid-air interface, including several arrangements that were previously unknown. Molecular dynamics simulations revealed the particular role of the liquid in templating the formation of superlattices not achievable through self-assembly in bulk solution. Second, upon stabilization, all of these binary superlattices could be transformed into distinct “nanoallotropes”—nanoporous materials having the same chemical composition but differing in their nanoscale architectures. article_processing_charge: No article_type: original author: - first_name: Thumu full_name: Udayabhaskararao, Thumu last_name: Udayabhaskararao - first_name: Thomas full_name: Altantzis, Thomas last_name: Altantzis - first_name: Lothar full_name: Houben, Lothar last_name: Houben - first_name: Marc full_name: Coronado-Puchau, Marc last_name: Coronado-Puchau - first_name: Judith full_name: Langer, Judith last_name: Langer - first_name: Ronit full_name: Popovitz-Biro, Ronit last_name: Popovitz-Biro - first_name: Luis M. full_name: Liz-Marzán, Luis M. last_name: Liz-Marzán - first_name: Lela full_name: Vuković, Lela last_name: Vuković - first_name: Petr full_name: Král, Petr last_name: Král - first_name: Sara full_name: Bals, Sara last_name: Bals - first_name: Rafal full_name: Klajn, Rafal id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b last_name: Klajn citation: ama: Udayabhaskararao T, Altantzis T, Houben L, et al. Tunable porous nanoallotropes prepared by post-assembly etching of binary nanoparticle superlattices. Science. 2017;358(6362):514-518. doi:10.1126/science.aan6046 apa: Udayabhaskararao, T., Altantzis, T., Houben, L., Coronado-Puchau, M., Langer, J., Popovitz-Biro, R., … Klajn, R. (2017). Tunable porous nanoallotropes prepared by post-assembly etching of binary nanoparticle superlattices. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.aan6046 chicago: Udayabhaskararao, Thumu, Thomas Altantzis, Lothar Houben, Marc Coronado-Puchau, Judith Langer, Ronit Popovitz-Biro, Luis M. Liz-Marzán, et al. “Tunable Porous Nanoallotropes Prepared by Post-Assembly Etching of Binary Nanoparticle Superlattices.” Science. American Association for the Advancement of Science, 2017. https://doi.org/10.1126/science.aan6046. ieee: T. Udayabhaskararao et al., “Tunable porous nanoallotropes prepared by post-assembly etching of binary nanoparticle superlattices,” Science, vol. 358, no. 6362. American Association for the Advancement of Science, pp. 514–518, 2017. ista: Udayabhaskararao T, Altantzis T, Houben L, Coronado-Puchau M, Langer J, Popovitz-Biro R, Liz-Marzán LM, Vuković L, Král P, Bals S, Klajn R. 2017. Tunable porous nanoallotropes prepared by post-assembly etching of binary nanoparticle superlattices. Science. 358(6362), 514–518. mla: Udayabhaskararao, Thumu, et al. “Tunable Porous Nanoallotropes Prepared by Post-Assembly Etching of Binary Nanoparticle Superlattices.” Science, vol. 358, no. 6362, American Association for the Advancement of Science, 2017, pp. 514–18, doi:10.1126/science.aan6046. short: T. Udayabhaskararao, T. Altantzis, L. Houben, M. Coronado-Puchau, J. Langer, R. Popovitz-Biro, L.M. Liz-Marzán, L. Vuković, P. Král, S. Bals, R. Klajn, Science 358 (2017) 514–518. date_created: 2023-08-01T09:41:16Z date_published: 2017-10-27T00:00:00Z date_updated: 2023-08-07T11:25:00Z day: '27' doi: 10.1126/science.aan6046 extern: '1' external_id: pmid: - '29074773' intvolume: ' 358' issue: '6362' keyword: - Multidisciplinary language: - iso: eng main_file_link: - open_access: '1' url: https://repository.uantwerpen.be/docman/irua/8d722e/147242_2018_06_07.pdf month: '10' oa: 1 oa_version: Submitted Version page: 514-518 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Tunable porous nanoallotropes prepared by post-assembly etching of binary nanoparticle superlattices type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 358 year: '2017' ... --- _id: '13384' abstract: - lang: eng text: Although methane is a volatile gas, it can be efficiently trapped in ice, which can then be readily set on fire. Beyond the curiosity of this “burning ice,” caged methane is of great importance as one of the world's largest natural gas resources. In these materials, known as clathrates, methane molecules are tightly bound in nanometer-sized, regularly interspaced cages. Other inorganic materials, such as the silica mineral chibaite, can similarly encapsulate methane and higher hydrocarbons. Simple organic compounds have also been found to trap various organic molecules upon crystallization. article_processing_charge: No article_type: original author: - first_name: Dipak full_name: Samanta, Dipak last_name: Samanta - first_name: Rafal full_name: Klajn, Rafal id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b last_name: Klajn citation: ama: Samanta D, Klajn R. Clathrates grow up. Science. 2017;355(6328):912-912. doi:10.1126/science.aam7927 apa: Samanta, D., & Klajn, R. (2017). Clathrates grow up. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.aam7927 chicago: Samanta, Dipak, and Rafal Klajn. “Clathrates Grow Up.” Science. American Association for the Advancement of Science, 2017. https://doi.org/10.1126/science.aam7927. ieee: D. Samanta and R. Klajn, “Clathrates grow up,” Science, vol. 355, no. 6328. American Association for the Advancement of Science, pp. 912–912, 2017. ista: Samanta D, Klajn R. 2017. Clathrates grow up. Science. 355(6328), 912–912. mla: Samanta, Dipak, and Rafal Klajn. “Clathrates Grow Up.” Science, vol. 355, no. 6328, American Association for the Advancement of Science, 2017, pp. 912–912, doi:10.1126/science.aam7927. short: D. Samanta, R. Klajn, Science 355 (2017) 912–912. date_created: 2023-08-01T09:41:55Z date_published: 2017-03-03T00:00:00Z date_updated: 2023-08-07T12:23:03Z day: '03' doi: 10.1126/science.aam7927 extern: '1' external_id: pmid: - '28254902' intvolume: ' 355' issue: '6328' keyword: - Multidisciplinary language: - iso: eng month: '03' oa_version: None page: 912-912 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Clathrates grow up type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 355 year: '2017' ... --- _id: '14008' abstract: - lang: eng text: Time-resolved x-ray absorption spectroscopy (TR-XAS) has so far practically been limited to large-scale facilities, to subpicosecond temporal resolution, and to the condensed phase. We report the realization of TR-XAS with a temporal resolution in the low femtosecond range by developing a tabletop high-harmonic source reaching up to 350 electron volts, thus partially covering the spectral region of 280 to 530 electron volts, where water is transmissive. We used this source to follow previously unexamined light-induced chemical reactions in the lowest electronic states of isolated CF4+ and SF6+ molecules in the gas phase. By probing element-specific core-to-valence transitions at the carbon K-edge or the sulfur L-edges, we characterized their reaction paths and observed the effect of symmetry breaking through the splitting of absorption bands and Rydberg-valence mixing induced by the geometry changes. article_processing_charge: No article_type: original author: - first_name: Yoann full_name: Pertot, Yoann last_name: Pertot - first_name: Cédric full_name: Schmidt, Cédric last_name: Schmidt - first_name: Mary full_name: Matthews, Mary last_name: Matthews - first_name: Adrien full_name: Chauvet, Adrien last_name: Chauvet - first_name: Martin full_name: Huppert, Martin last_name: Huppert - first_name: Vit full_name: Svoboda, Vit last_name: Svoboda - first_name: Aaron full_name: von Conta, Aaron last_name: von Conta - first_name: Andres full_name: Tehlar, Andres last_name: Tehlar - first_name: Denitsa Rangelova full_name: Baykusheva, Denitsa Rangelova id: 71b4d059-2a03-11ee-914d-dfa3beed6530 last_name: Baykusheva - first_name: Jean-Pierre full_name: Wolf, Jean-Pierre last_name: Wolf - first_name: Hans Jakob full_name: Wörner, Hans Jakob last_name: Wörner citation: ama: Pertot Y, Schmidt C, Matthews M, et al. Time-resolved x-ray absorption spectroscopy with a water window high-harmonic source. Science. 2017;355(6322):264-267. doi:10.1126/science.aah6114 apa: Pertot, Y., Schmidt, C., Matthews, M., Chauvet, A., Huppert, M., Svoboda, V., … Wörner, H. J. (2017). Time-resolved x-ray absorption spectroscopy with a water window high-harmonic source. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.aah6114 chicago: Pertot, Yoann, Cédric Schmidt, Mary Matthews, Adrien Chauvet, Martin Huppert, Vit Svoboda, Aaron von Conta, et al. “Time-Resolved x-Ray Absorption Spectroscopy with a Water Window High-Harmonic Source.” Science. American Association for the Advancement of Science, 2017. https://doi.org/10.1126/science.aah6114. ieee: Y. Pertot et al., “Time-resolved x-ray absorption spectroscopy with a water window high-harmonic source,” Science, vol. 355, no. 6322. American Association for the Advancement of Science, pp. 264–267, 2017. ista: Pertot Y, Schmidt C, Matthews M, Chauvet A, Huppert M, Svoboda V, von Conta A, Tehlar A, Baykusheva DR, Wolf J-P, Wörner HJ. 2017. Time-resolved x-ray absorption spectroscopy with a water window high-harmonic source. Science. 355(6322), 264–267. mla: Pertot, Yoann, et al. “Time-Resolved x-Ray Absorption Spectroscopy with a Water Window High-Harmonic Source.” Science, vol. 355, no. 6322, American Association for the Advancement of Science, 2017, pp. 264–67, doi:10.1126/science.aah6114. short: Y. Pertot, C. Schmidt, M. Matthews, A. Chauvet, M. Huppert, V. Svoboda, A. von Conta, A. Tehlar, D.R. Baykusheva, J.-P. Wolf, H.J. Wörner, Science 355 (2017) 264–267. date_created: 2023-08-10T06:36:39Z date_published: 2017-01-05T00:00:00Z date_updated: 2023-08-22T08:34:38Z day: '05' doi: 10.1126/science.aah6114 extern: '1' external_id: pmid: - '28059713' intvolume: ' 355' issue: '6322' keyword: - Multidisciplinary language: - iso: eng month: '01' oa_version: None page: 264-267 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Time-resolved x-ray absorption spectroscopy with a water window high-harmonic source type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 355 year: '2017' ... --- _id: '14287' abstract: - lang: eng text: We describe an approach to bottom-up fabrication that allows integration of the functional diversity of proteins into designed three-dimensional structural frameworks. A set of custom staple proteins based on transcription activator–like effector proteins folds a double-stranded DNA template into a user-defined shape. Each staple protein is designed to recognize and closely link two distinct double-helical DNA sequences at separate positions on the template. We present design rules for constructing megadalton-scale DNA-protein hybrid shapes; introduce various structural motifs, such as custom curvature, corners, and vertices; and describe principles for creating multilayer DNA-protein objects with enhanced rigidity. We demonstrate self-assembly of our hybrid nanostructures in one-pot mixtures that include the genetic information for the designed proteins, the template DNA, RNA polymerase, ribosomes, and cofactors for transcription and translation. article_number: eaam5488 article_processing_charge: No article_type: original author: - first_name: Florian M full_name: Praetorius, Florian M id: dfec9381-4341-11ee-8fd8-faa02bba7d62 last_name: Praetorius - first_name: Hendrik full_name: Dietz, Hendrik last_name: Dietz citation: ama: Praetorius FM, Dietz H. Self-assembly of genetically encoded DNA-protein hybrid nanoscale shapes. Science. 2017;355(6331). doi:10.1126/science.aam5488 apa: Praetorius, F. M., & Dietz, H. (2017). Self-assembly of genetically encoded DNA-protein hybrid nanoscale shapes. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.aam5488 chicago: Praetorius, Florian M, and Hendrik Dietz. “Self-Assembly of Genetically Encoded DNA-Protein Hybrid Nanoscale Shapes.” Science. American Association for the Advancement of Science, 2017. https://doi.org/10.1126/science.aam5488. ieee: F. M. Praetorius and H. Dietz, “Self-assembly of genetically encoded DNA-protein hybrid nanoscale shapes,” Science, vol. 355, no. 6331. American Association for the Advancement of Science, 2017. ista: Praetorius FM, Dietz H. 2017. Self-assembly of genetically encoded DNA-protein hybrid nanoscale shapes. Science. 355(6331), eaam5488. mla: Praetorius, Florian M., and Hendrik Dietz. “Self-Assembly of Genetically Encoded DNA-Protein Hybrid Nanoscale Shapes.” Science, vol. 355, no. 6331, eaam5488, American Association for the Advancement of Science, 2017, doi:10.1126/science.aam5488. short: F.M. Praetorius, H. Dietz, Science 355 (2017). date_created: 2023-09-06T12:08:55Z date_published: 2017-03-24T00:00:00Z date_updated: 2023-11-07T12:33:05Z day: '24' doi: 10.1126/science.aam5488 extern: '1' external_id: pmid: - '28336611' intvolume: ' 355' issue: '6331' language: - iso: eng month: '03' oa_version: None pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Self-assembly of genetically encoded DNA-protein hybrid nanoscale shapes type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 355 year: '2017' ... --- _id: '15156' abstract: - lang: eng text: Circadian clocks are ubiquitous timing systems that induce rhythms of biological activities in synchrony with night and day. In cyanobacteria, timing is generated by a posttranslational clock consisting of KaiA, KaiB, and KaiC proteins and a set of output signaling proteins, SasA and CikA, which transduce this rhythm to control gene expression. Here, we describe crystal and nuclear magnetic resonance structures of KaiB-KaiC,KaiA-KaiB-KaiC, and CikA-KaiB complexes. They reveal how the metamorphic properties of KaiB, a protein that adopts two distinct folds, and the post–adenosine triphosphate hydrolysis state of KaiC create a hub around which nighttime signaling events revolve, including inactivation of KaiA and reciprocal regulation of the mutually antagonistic signaling proteins, SasA and CikA. article_processing_charge: No article_type: original author: - first_name: Roger full_name: Tseng, Roger last_name: Tseng - first_name: Nicolette F. full_name: Goularte, Nicolette F. last_name: Goularte - first_name: Archana full_name: Chavan, Archana last_name: Chavan - first_name: Jansen full_name: Luu, Jansen last_name: Luu - first_name: Susan E. full_name: Cohen, Susan E. last_name: Cohen - first_name: Yong-Gang full_name: Chang, Yong-Gang last_name: Chang - first_name: Joel full_name: Heisler, Joel last_name: Heisler - first_name: Sheng full_name: Li, Sheng last_name: Li - first_name: Alicia Kathleen full_name: Michael, Alicia Kathleen id: 6437c950-2a03-11ee-914d-d6476dd7b75c last_name: Michael - first_name: Sarvind full_name: Tripathi, Sarvind last_name: Tripathi - first_name: Susan S. full_name: Golden, Susan S. last_name: Golden - first_name: Andy full_name: LiWang, Andy last_name: LiWang - first_name: Carrie L. full_name: Partch, Carrie L. last_name: Partch citation: ama: Tseng R, Goularte NF, Chavan A, et al. Structural basis of the day-night transition in a bacterial circadian clock. Science. 2017;355(6330):1174-1180. doi:10.1126/science.aag2516 apa: Tseng, R., Goularte, N. F., Chavan, A., Luu, J., Cohen, S. E., Chang, Y.-G., … Partch, C. L. (2017). Structural basis of the day-night transition in a bacterial circadian clock. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.aag2516 chicago: Tseng, Roger, Nicolette F. Goularte, Archana Chavan, Jansen Luu, Susan E. Cohen, Yong-Gang Chang, Joel Heisler, et al. “Structural Basis of the Day-Night Transition in a Bacterial Circadian Clock.” Science. American Association for the Advancement of Science, 2017. https://doi.org/10.1126/science.aag2516. ieee: R. Tseng et al., “Structural basis of the day-night transition in a bacterial circadian clock,” Science, vol. 355, no. 6330. American Association for the Advancement of Science, pp. 1174–1180, 2017. ista: Tseng R, Goularte NF, Chavan A, Luu J, Cohen SE, Chang Y-G, Heisler J, Li S, Michael AK, Tripathi S, Golden SS, LiWang A, Partch CL. 2017. Structural basis of the day-night transition in a bacterial circadian clock. Science. 355(6330), 1174–1180. mla: Tseng, Roger, et al. “Structural Basis of the Day-Night Transition in a Bacterial Circadian Clock.” Science, vol. 355, no. 6330, American Association for the Advancement of Science, 2017, pp. 1174–80, doi:10.1126/science.aag2516. short: R. Tseng, N.F. Goularte, A. Chavan, J. Luu, S.E. Cohen, Y.-G. Chang, J. Heisler, S. Li, A.K. Michael, S. Tripathi, S.S. Golden, A. LiWang, C.L. Partch, Science 355 (2017) 1174–1180. date_created: 2024-03-21T07:56:24Z date_published: 2017-03-17T00:00:00Z date_updated: 2024-03-25T12:16:44Z day: '17' doi: 10.1126/science.aag2516 extern: '1' intvolume: ' 355' issue: '6330' keyword: - Multidisciplinary language: - iso: eng month: '03' oa_version: None page: 1174-1180 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Structural basis of the day-night transition in a bacterial circadian clock type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 355 year: '2017' ... --- _id: '14013' abstract: - lang: eng text: The ultrafast motion of electrons and holes after light-matter interaction is fundamental to a broad range of chemical and biophysical processes. We advanced high-harmonic spectroscopy to resolve spatially and temporally the migration of an electron hole immediately after ionization of iodoacetylene while simultaneously demonstrating extensive control over the process. A multidimensional approach, based on the measurement and accurate theoretical description of both even and odd harmonic orders, enabled us to reconstruct both quantum amplitudes and phases of the electronic states with a resolution of ~100 attoseconds. We separately reconstructed quasi-field-free and laser-controlled charge migration as a function of the spatial orientation of the molecule and determined the shape of the hole created by ionization. Our technique opens the prospect of laser control over electronic primary processes. article_processing_charge: No article_type: original author: - first_name: P. M. full_name: Kraus, P. M. last_name: Kraus - first_name: B. full_name: Mignolet, B. last_name: Mignolet - first_name: Denitsa Rangelova full_name: Baykusheva, Denitsa Rangelova id: 71b4d059-2a03-11ee-914d-dfa3beed6530 last_name: Baykusheva - first_name: A. full_name: Rupenyan, A. last_name: Rupenyan - first_name: L. full_name: Horný, L. last_name: Horný - first_name: E. F. full_name: Penka, E. F. last_name: Penka - first_name: G. full_name: Grassi, G. last_name: Grassi - first_name: O. I. full_name: Tolstikhin, O. I. last_name: Tolstikhin - first_name: J. full_name: Schneider, J. last_name: Schneider - first_name: F. full_name: Jensen, F. last_name: Jensen - first_name: L. B. full_name: Madsen, L. B. last_name: Madsen - first_name: A. D. full_name: Bandrauk, A. D. last_name: Bandrauk - first_name: F. full_name: Remacle, F. last_name: Remacle - first_name: H. J. full_name: Wörner, H. J. last_name: Wörner citation: ama: Kraus PM, Mignolet B, Baykusheva DR, et al. Measurement and laser control of attosecond charge migration in ionized iodoacetylene. Science. 2015;350(6262):790-795. doi:10.1126/science.aab2160 apa: Kraus, P. M., Mignolet, B., Baykusheva, D. R., Rupenyan, A., Horný, L., Penka, E. F., … Wörner, H. J. (2015). Measurement and laser control of attosecond charge migration in ionized iodoacetylene. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.aab2160 chicago: Kraus, P. M., B. Mignolet, Denitsa Rangelova Baykusheva, A. Rupenyan, L. Horný, E. F. Penka, G. Grassi, et al. “Measurement and Laser Control of Attosecond Charge Migration in Ionized Iodoacetylene.” Science. American Association for the Advancement of Science, 2015. https://doi.org/10.1126/science.aab2160. ieee: P. M. Kraus et al., “Measurement and laser control of attosecond charge migration in ionized iodoacetylene,” Science, vol. 350, no. 6262. American Association for the Advancement of Science, pp. 790–795, 2015. ista: Kraus PM, Mignolet B, Baykusheva DR, Rupenyan A, Horný L, Penka EF, Grassi G, Tolstikhin OI, Schneider J, Jensen F, Madsen LB, Bandrauk AD, Remacle F, Wörner HJ. 2015. Measurement and laser control of attosecond charge migration in ionized iodoacetylene. Science. 350(6262), 790–795. mla: Kraus, P. M., et al. “Measurement and Laser Control of Attosecond Charge Migration in Ionized Iodoacetylene.” Science, vol. 350, no. 6262, American Association for the Advancement of Science, 2015, pp. 790–95, doi:10.1126/science.aab2160. short: P.M. Kraus, B. Mignolet, D.R. Baykusheva, A. Rupenyan, L. Horný, E.F. Penka, G. Grassi, O.I. Tolstikhin, J. Schneider, F. Jensen, L.B. Madsen, A.D. Bandrauk, F. Remacle, H.J. Wörner, Science 350 (2015) 790–795. date_created: 2023-08-10T06:37:35Z date_published: 2015-10-22T00:00:00Z date_updated: 2023-08-22T08:47:39Z day: '22' doi: 10.1126/science.aab2160 extern: '1' external_id: pmid: - '26494175' intvolume: ' 350' issue: '6262' keyword: - Multidisciplinary language: - iso: eng month: '10' oa_version: None page: 790-795 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Measurement and laser control of attosecond charge migration in ionized iodoacetylene type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 350 year: '2015' ... --- _id: '13400' abstract: - lang: eng text: Organizing inorganic nanocrystals into complex architectures is challenging and typically relies on preexisting templates, such as properly folded DNA or polypeptide chains. We found that under carefully controlled conditions, cubic nanocrystals of magnetite self-assemble into arrays of helical superstructures in a template-free manner with >99% yield. Computer simulations revealed that the formation of helices is determined by the interplay of van der Waals and magnetic dipole-dipole interactions, Zeeman coupling, and entropic forces and can be attributed to spontaneous formation of chiral nanocube clusters. Neighboring helices within their densely packed ensembles tended to adopt the same handedness in order to maximize packing, thus revealing a novel mechanism of symmetry breaking and chirality amplification. article_processing_charge: No article_type: original author: - first_name: Gurvinder full_name: Singh, Gurvinder last_name: Singh - first_name: Henry full_name: Chan, Henry last_name: Chan - first_name: Artem full_name: Baskin, Artem last_name: Baskin - first_name: Elijah full_name: Gelman, Elijah last_name: Gelman - first_name: Nikita full_name: Repnin, Nikita last_name: Repnin - first_name: Petr full_name: Král, Petr last_name: Král - first_name: Rafal full_name: Klajn, Rafal id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b last_name: Klajn citation: ama: Singh G, Chan H, Baskin A, et al. Self-assembly of magnetite nanocubes into helical superstructures. Science. 2014;345(6201):1149-1153. doi:10.1126/science.1254132 apa: Singh, G., Chan, H., Baskin, A., Gelman, E., Repnin, N., Král, P., & Klajn, R. (2014). Self-assembly of magnetite nanocubes into helical superstructures. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1254132 chicago: Singh, Gurvinder, Henry Chan, Artem Baskin, Elijah Gelman, Nikita Repnin, Petr Král, and Rafal Klajn. “Self-Assembly of Magnetite Nanocubes into Helical Superstructures.” Science. American Association for the Advancement of Science, 2014. https://doi.org/10.1126/science.1254132. ieee: G. Singh et al., “Self-assembly of magnetite nanocubes into helical superstructures,” Science, vol. 345, no. 6201. American Association for the Advancement of Science, pp. 1149–1153, 2014. ista: Singh G, Chan H, Baskin A, Gelman E, Repnin N, Král P, Klajn R. 2014. Self-assembly of magnetite nanocubes into helical superstructures. Science. 345(6201), 1149–1153. mla: Singh, Gurvinder, et al. “Self-Assembly of Magnetite Nanocubes into Helical Superstructures.” Science, vol. 345, no. 6201, American Association for the Advancement of Science, 2014, pp. 1149–53, doi:10.1126/science.1254132. short: G. Singh, H. Chan, A. Baskin, E. Gelman, N. Repnin, P. Král, R. Klajn, Science 345 (2014) 1149–1153. date_created: 2023-08-01T09:45:56Z date_published: 2014-07-24T00:00:00Z date_updated: 2023-08-08T07:23:05Z day: '24' doi: 10.1126/science.1254132 extern: '1' external_id: pmid: - '25061133' intvolume: ' 345' issue: '6201' keyword: - Multidisciplinary language: - iso: eng month: '07' oa_version: None page: 1149-1153 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Self-assembly of magnetite nanocubes into helical superstructures type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 345 year: '2014' ... --- _id: '9055' abstract: - lang: eng text: Spontaneous formation of colonies of bacteria or flocks of birds are examples of self-organization in active living matter. Here, we demonstrate a form of self-organization from nonequilibrium driving forces in a suspension of synthetic photoactivated colloidal particles. They lead to two-dimensional "living crystals," which form, break, explode, and re-form elsewhere. The dynamic assembly results from a competition between self-propulsion of particles and an attractive interaction induced respectively by osmotic and phoretic effects and activated by light. We measured a transition from normal to giant-number fluctuations. Our experiments are quantitatively described by simple numerical simulations. We show that the existence of the living crystals is intrinsically related to the out-of-equilibrium collisions of the self-propelled particles. article_processing_charge: No article_type: original author: - first_name: Jérémie A full_name: Palacci, Jérémie A id: 8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d last_name: Palacci orcid: 0000-0002-7253-9465 - first_name: S. full_name: Sacanna, S. last_name: Sacanna - first_name: A. P. full_name: Steinberg, A. P. last_name: Steinberg - first_name: D. J. full_name: Pine, D. J. last_name: Pine - first_name: P. M. full_name: Chaikin, P. M. last_name: Chaikin citation: ama: Palacci JA, Sacanna S, Steinberg AP, Pine DJ, Chaikin PM. Living crystals of light-activated colloidal surfers. Science. 2013;339(6122):936-940. doi:10.1126/science.1230020 apa: Palacci, J. A., Sacanna, S., Steinberg, A. P., Pine, D. J., & Chaikin, P. M. (2013). Living crystals of light-activated colloidal surfers. Science. American Association for the Advancement of Science . https://doi.org/10.1126/science.1230020 chicago: Palacci, Jérémie A, S. Sacanna, A. P. Steinberg, D. J. Pine, and P. M. Chaikin. “Living Crystals of Light-Activated Colloidal Surfers.” Science. American Association for the Advancement of Science , 2013. https://doi.org/10.1126/science.1230020. ieee: J. A. Palacci, S. Sacanna, A. P. Steinberg, D. J. Pine, and P. M. Chaikin, “Living crystals of light-activated colloidal surfers,” Science, vol. 339, no. 6122. American Association for the Advancement of Science , pp. 936–940, 2013. ista: Palacci JA, Sacanna S, Steinberg AP, Pine DJ, Chaikin PM. 2013. Living crystals of light-activated colloidal surfers. Science. 339(6122), 936–940. mla: Palacci, Jérémie A., et al. “Living Crystals of Light-Activated Colloidal Surfers.” Science, vol. 339, no. 6122, American Association for the Advancement of Science , 2013, pp. 936–40, doi:10.1126/science.1230020. short: J.A. Palacci, S. Sacanna, A.P. Steinberg, D.J. Pine, P.M. Chaikin, Science 339 (2013) 936–940. date_created: 2021-02-01T14:37:29Z date_published: 2013-02-22T00:00:00Z date_updated: 2022-08-25T14:57:43Z day: '22' doi: 10.1126/science.1230020 extern: '1' external_id: pmid: - '23371555' intvolume: ' 339' issue: '6122' keyword: - Multidisciplinary language: - iso: eng month: '02' oa_version: None page: 936-940 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: 'American Association for the Advancement of Science ' quality_controlled: '1' scopus_import: '1' status: public title: Living crystals of light-activated colloidal surfers type: journal_article user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87 volume: 339 year: '2013' ... --- _id: '11092' abstract: - lang: eng text: To combat the functional decline of the proteome, cells use the process of protein turnover to replace potentially impaired polypeptides with new functional copies. We found that extremely long-lived proteins (ELLPs) did not turn over in postmitotic cells of the rat central nervous system. These ELLPs were associated with chromatin and the nuclear pore complex, the central transport channels that mediate all molecular trafficking in and out of the nucleus. The longevity of these proteins would be expected to expose them to potentially harmful metabolites, putting them at risk of accumulating damage over extended periods of time. Thus, it is possible that failure to maintain proper levels and functional integrity of ELLPs in nonproliferative cells might contribute to age-related deterioration in cell and tissue function. article_processing_charge: No article_type: letter_note author: - first_name: Jeffrey N. full_name: Savas, Jeffrey N. last_name: Savas - first_name: Brandon H. full_name: Toyama, Brandon H. last_name: Toyama - first_name: Tao full_name: Xu, Tao last_name: Xu - first_name: John R. full_name: Yates, John R. last_name: Yates - first_name: Martin W full_name: HETZER, Martin W id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed last_name: HETZER orcid: 0000-0002-2111-992X citation: ama: Savas JN, Toyama BH, Xu T, Yates JR, Hetzer M. Extremely long-lived nuclear pore proteins in the rat brain. Science. 2012;335(6071):942-942. doi:10.1126/science.1217421 apa: Savas, J. N., Toyama, B. H., Xu, T., Yates, J. R., & Hetzer, M. (2012). Extremely long-lived nuclear pore proteins in the rat brain. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1217421 chicago: Savas, Jeffrey N., Brandon H. Toyama, Tao Xu, John R. Yates, and Martin Hetzer. “Extremely Long-Lived Nuclear Pore Proteins in the Rat Brain.” Science. American Association for the Advancement of Science, 2012. https://doi.org/10.1126/science.1217421. ieee: J. N. Savas, B. H. Toyama, T. Xu, J. R. Yates, and M. Hetzer, “Extremely long-lived nuclear pore proteins in the rat brain,” Science, vol. 335, no. 6071. American Association for the Advancement of Science, pp. 942–942, 2012. ista: Savas JN, Toyama BH, Xu T, Yates JR, Hetzer M. 2012. Extremely long-lived nuclear pore proteins in the rat brain. Science. 335(6071), 942–942. mla: Savas, Jeffrey N., et al. “Extremely Long-Lived Nuclear Pore Proteins in the Rat Brain.” Science, vol. 335, no. 6071, American Association for the Advancement of Science, 2012, pp. 942–942, doi:10.1126/science.1217421. short: J.N. Savas, B.H. Toyama, T. Xu, J.R. Yates, M. Hetzer, Science 335 (2012) 942–942. date_created: 2022-04-07T07:52:01Z date_published: 2012-02-02T00:00:00Z date_updated: 2022-07-18T08:53:06Z day: '02' doi: 10.1126/science.1217421 extern: '1' external_id: pmid: - '22300851' intvolume: ' 335' issue: '6071' keyword: - Multidisciplinary language: - iso: eng month: '02' oa_version: None page: 942-942 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Extremely long-lived nuclear pore proteins in the rat brain type: journal_article user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd volume: 335 year: '2012' ... --- _id: '7310' abstract: - lang: eng text: The rechargeable nonaqueous lithium-air (Li-O2) battery is receiving a great deal of interest because, theoretically, its specific energy far exceeds the best that can be achieved with lithium-ion cells. Operation of the rechargeable Li-O2 battery depends critically on repeated and highly reversible formation/decomposition of lithium peroxide (Li2O2) at the cathode upon cycling. Here, we show that this process is possible with the use of a dimethyl sulfoxide electrolyte and a porous gold electrode (95% capacity retention from cycles 1 to 100), whereas previously only partial Li2O2 formation/decomposition and limited cycling could occur. Furthermore, we present data indicating that the kinetics of Li2O2 oxidation on charge is approximately 10 times faster than on carbon electrodes. article_processing_charge: No article_type: original author: - first_name: Z. full_name: Peng, Z. last_name: Peng - first_name: Stefan Alexander full_name: Freunberger, Stefan Alexander id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425 last_name: Freunberger orcid: 0000-0003-2902-5319 - first_name: Y. full_name: Chen, Y. last_name: Chen - first_name: P. G. full_name: Bruce, P. G. last_name: Bruce citation: ama: Peng Z, Freunberger SA, Chen Y, Bruce PG. A reversible and higher-rate Li-O2 battery. Science. 2012;337(6094):563-566. doi:10.1126/science.1223985 apa: Peng, Z., Freunberger, S. A., Chen, Y., & Bruce, P. G. (2012). A reversible and higher-rate Li-O2 battery. Science. AAAS. https://doi.org/10.1126/science.1223985 chicago: Peng, Z., Stefan Alexander Freunberger, Y. Chen, and P. G. Bruce. “A Reversible and Higher-Rate Li-O2 Battery.” Science. AAAS, 2012. https://doi.org/10.1126/science.1223985. ieee: Z. Peng, S. A. Freunberger, Y. Chen, and P. G. Bruce, “A reversible and higher-rate Li-O2 battery,” Science, vol. 337, no. 6094. AAAS, pp. 563–566, 2012. ista: Peng Z, Freunberger SA, Chen Y, Bruce PG. 2012. A reversible and higher-rate Li-O2 battery. Science. 337(6094), 563–566. mla: Peng, Z., et al. “A Reversible and Higher-Rate Li-O2 Battery.” Science, vol. 337, no. 6094, AAAS, 2012, pp. 563–66, doi:10.1126/science.1223985. short: Z. Peng, S.A. Freunberger, Y. Chen, P.G. Bruce, Science 337 (2012) 563–566. date_created: 2020-01-15T12:19:23Z date_published: 2012-08-03T00:00:00Z date_updated: 2021-01-12T08:12:57Z day: '03' doi: 10.1126/science.1223985 extern: '1' intvolume: ' 337' issue: '6094' language: - iso: eng month: '08' oa_version: None page: 563-566 publication: Science publication_identifier: issn: - 0036-8075 - 1095-9203 publication_status: published publisher: AAAS quality_controlled: '1' status: public title: A reversible and higher-rate Li-O2 battery type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 337 year: '2012' ... --- _id: '9451' abstract: - lang: eng text: The Arabidopsis thaliana central cell, the companion cell of the egg, undergoes DNA demethylation before fertilization, but the targeting preferences, mechanism, and biological significance of this process remain unclear. Here, we show that active DNA demethylation mediated by the DEMETER DNA glycosylase accounts for all of the demethylation in the central cell and preferentially targets small, AT-rich, and nucleosome-depleted euchromatic transposable elements. The vegetative cell, the companion cell of sperm, also undergoes DEMETER-dependent demethylation of similar sequences, and lack of DEMETER in vegetative cells causes reduced small RNA–directed DNA methylation of transposons in sperm. Our results demonstrate that demethylation in companion cells reinforces transposon methylation in plant gametes and likely contributes to stable silencing of transposable elements across generations. article_processing_charge: No article_type: original author: - first_name: Christian A. full_name: Ibarra, Christian A. last_name: Ibarra - first_name: Xiaoqi full_name: Feng, Xiaoqi last_name: Feng - first_name: Vera K. full_name: Schoft, Vera K. last_name: Schoft - first_name: Tzung-Fu full_name: Hsieh, Tzung-Fu last_name: Hsieh - first_name: Rie full_name: Uzawa, Rie last_name: Uzawa - first_name: Jessica A. full_name: Rodrigues, Jessica A. last_name: Rodrigues - first_name: Assaf full_name: Zemach, Assaf last_name: Zemach - first_name: Nina full_name: Chumak, Nina last_name: Chumak - first_name: Adriana full_name: Machlicova, Adriana last_name: Machlicova - first_name: Toshiro full_name: Nishimura, Toshiro last_name: Nishimura - first_name: Denisse full_name: Rojas, Denisse last_name: Rojas - first_name: Robert L. full_name: Fischer, Robert L. last_name: Fischer - first_name: Hisashi full_name: Tamaru, Hisashi last_name: Tamaru - first_name: Daniel full_name: Zilberman, Daniel id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1 last_name: Zilberman orcid: 0000-0002-0123-8649 citation: ama: Ibarra CA, Feng X, Schoft VK, et al. Active DNA demethylation in plant companion cells reinforces transposon methylation in gametes. Science. 2012;337(6100):1360-1364. doi:10.1126/science.1224839 apa: Ibarra, C. A., Feng, X., Schoft, V. K., Hsieh, T.-F., Uzawa, R., Rodrigues, J. A., … Zilberman, D. (2012). Active DNA demethylation in plant companion cells reinforces transposon methylation in gametes. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1224839 chicago: Ibarra, Christian A., Xiaoqi Feng, Vera K. Schoft, Tzung-Fu Hsieh, Rie Uzawa, Jessica A. Rodrigues, Assaf Zemach, et al. “Active DNA Demethylation in Plant Companion Cells Reinforces Transposon Methylation in Gametes.” Science. American Association for the Advancement of Science, 2012. https://doi.org/10.1126/science.1224839. ieee: C. A. Ibarra et al., “Active DNA demethylation in plant companion cells reinforces transposon methylation in gametes,” Science, vol. 337, no. 6100. American Association for the Advancement of Science, pp. 1360–1364, 2012. ista: Ibarra CA, Feng X, Schoft VK, Hsieh T-F, Uzawa R, Rodrigues JA, Zemach A, Chumak N, Machlicova A, Nishimura T, Rojas D, Fischer RL, Tamaru H, Zilberman D. 2012. Active DNA demethylation in plant companion cells reinforces transposon methylation in gametes. Science. 337(6100), 1360–1364. mla: Ibarra, Christian A., et al. “Active DNA Demethylation in Plant Companion Cells Reinforces Transposon Methylation in Gametes.” Science, vol. 337, no. 6100, American Association for the Advancement of Science, 2012, pp. 1360–64, doi:10.1126/science.1224839. short: C.A. Ibarra, X. Feng, V.K. Schoft, T.-F. Hsieh, R. Uzawa, J.A. Rodrigues, A. Zemach, N. Chumak, A. Machlicova, T. Nishimura, D. Rojas, R.L. Fischer, H. Tamaru, D. Zilberman, Science 337 (2012) 1360–1364. date_created: 2021-06-04T07:51:31Z date_published: 2012-09-14T00:00:00Z date_updated: 2021-12-14T08:28:51Z day: '14' ddc: - '580' department: - _id: DaZi doi: 10.1126/science.1224839 extern: '1' external_id: pmid: - '22984074' has_accepted_license: '1' intvolume: ' 337' issue: '6100' language: - iso: eng main_file_link: - open_access: '1' url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034762/ month: '09' oa: 1 oa_version: Published Version page: 1360-1364 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Active DNA demethylation in plant companion cells reinforces transposon methylation in gametes type: journal_article user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9 volume: 337 year: '2012' ... --- _id: '12198' abstract: - lang: eng text: The Arabidopsis thaliana central cell, the companion cell of the egg, undergoes DNA demethylation before fertilization, but the targeting preferences, mechanism, and biological significance of this process remain unclear. Here, we show that active DNA demethylation mediated by the DEMETER DNA glycosylase accounts for all of the demethylation in the central cell and preferentially targets small, AT-rich, and nucleosome-depleted euchromatic transposable elements. The vegetative cell, the companion cell of sperm, also undergoes DEMETER-dependent demethylation of similar sequences, and lack of DEMETER in vegetative cells causes reduced small RNA–directed DNA methylation of transposons in sperm. Our results demonstrate that demethylation in companion cells reinforces transposon methylation in plant gametes and likely contributes to stable silencing of transposable elements across generations. acknowledgement: We thank S. Harmer for assistance with the analysis of histone modifications, the BioOptics team at the Vienna Biocenter Campus for sorting sperm and vegetative cell nuclei, K. Slotkin for the LAT52p-amiRNA=GFP plasmid, and G. Drews for the DD45p-GFP transgenic line. This work was partially funded by an NIH grant (GM69415) to R.L.F., NSF grants (MCB-0918821 and IOS-1025890) to R.L.F. and D.Z., a Young Investigator Grant from the Arnold and Mabel Beckman Foundation to D.Z., an Austrian Science Fund (FWF) grant P21389-B03 to H.T., a Ruth L. Kirschstein NIH Predoctoral Fellowship (GM093633) to C.A.I., a Fulbright Scholarship to J.A.R., a fellowship from the Jane Coffin Childs Memorial Fund to A.Z., and a Robert and Colleen Haas Scholarship to D.R. Sequencing data are deposited in GEO (GSE38935). article_processing_charge: No article_type: original author: - first_name: Christian A. full_name: Ibarra, Christian A. last_name: Ibarra - first_name: Xiaoqi full_name: Feng, Xiaoqi id: e0164712-22ee-11ed-b12a-d80fcdf35958 last_name: Feng orcid: 0000-0002-4008-1234 - first_name: Vera K. full_name: Schoft, Vera K. last_name: Schoft - first_name: Tzung-Fu full_name: Hsieh, Tzung-Fu last_name: Hsieh - first_name: Rie full_name: Uzawa, Rie last_name: Uzawa - first_name: Jessica A. full_name: Rodrigues, Jessica A. last_name: Rodrigues - first_name: Assaf full_name: Zemach, Assaf last_name: Zemach - first_name: Nina full_name: Chumak, Nina last_name: Chumak - first_name: Adriana full_name: Machlicova, Adriana last_name: Machlicova - first_name: Toshiro full_name: Nishimura, Toshiro last_name: Nishimura - first_name: Denisse full_name: Rojas, Denisse last_name: Rojas - first_name: Robert L. full_name: Fischer, Robert L. last_name: Fischer - first_name: Hisashi full_name: Tamaru, Hisashi last_name: Tamaru - first_name: Daniel full_name: Zilberman, Daniel last_name: Zilberman citation: ama: Ibarra CA, Feng X, Schoft VK, et al. Active DNA demethylation in plant companion cells reinforces transposon methylation in gametes. Science. 2012;337(6100):1360-1364. doi:10.1126/science.1224839 apa: Ibarra, C. A., Feng, X., Schoft, V. K., Hsieh, T.-F., Uzawa, R., Rodrigues, J. A., … Zilberman, D. (2012). Active DNA demethylation in plant companion cells reinforces transposon methylation in gametes. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1224839 chicago: Ibarra, Christian A., Xiaoqi Feng, Vera K. Schoft, Tzung-Fu Hsieh, Rie Uzawa, Jessica A. Rodrigues, Assaf Zemach, et al. “Active DNA Demethylation in Plant Companion Cells Reinforces Transposon Methylation in Gametes.” Science. American Association for the Advancement of Science, 2012. https://doi.org/10.1126/science.1224839. ieee: C. A. Ibarra et al., “Active DNA demethylation in plant companion cells reinforces transposon methylation in gametes,” Science, vol. 337, no. 6100. American Association for the Advancement of Science, pp. 1360–1364, 2012. ista: Ibarra CA, Feng X, Schoft VK, Hsieh T-F, Uzawa R, Rodrigues JA, Zemach A, Chumak N, Machlicova A, Nishimura T, Rojas D, Fischer RL, Tamaru H, Zilberman D. 2012. Active DNA demethylation in plant companion cells reinforces transposon methylation in gametes. Science. 337(6100), 1360–1364. mla: Ibarra, Christian A., et al. “Active DNA Demethylation in Plant Companion Cells Reinforces Transposon Methylation in Gametes.” Science, vol. 337, no. 6100, American Association for the Advancement of Science, 2012, pp. 1360–64, doi:10.1126/science.1224839. short: C.A. Ibarra, X. Feng, V.K. Schoft, T.-F. Hsieh, R. Uzawa, J.A. Rodrigues, A. Zemach, N. Chumak, A. Machlicova, T. Nishimura, D. Rojas, R.L. Fischer, H. Tamaru, D. Zilberman, Science 337 (2012) 1360–1364. date_created: 2023-01-16T09:21:24Z date_published: 2012-09-14T00:00:00Z date_updated: 2023-10-16T09:27:26Z day: '14' department: - _id: XiFe doi: 10.1126/science.1224839 external_id: pmid: - '22984074' intvolume: ' 337' issue: '6100' keyword: - Multidisciplinary language: - iso: eng main_file_link: - open_access: '1' url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034762/ month: '09' oa: 1 oa_version: Published Version page: 1360-1364 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Active DNA demethylation in plant companion cells reinforces transposon methylation in gametes type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 337 year: '2012' ... --- _id: '8074' abstract: - lang: eng text: Cortical neurons receive balanced excitatory and inhibitory synaptic currents. Such a balance could be established and maintained in an experience-dependent manner by synaptic plasticity at inhibitory synapses. We show that this mechanism provides an explanation for the sparse firing patterns observed in response to natural stimuli and fits well with a recently observed interaction of excitatory and inhibitory receptive field plasticity. The introduction of inhibitory plasticity in suitable recurrent networks provides a homeostatic mechanism that leads to asynchronous irregular network states. Further, it can accommodate synaptic memories with activity patterns that become indiscernible from the background state but can be reactivated by external stimuli. Our results suggest an essential role of inhibitory plasticity in the formation and maintenance of functional cortical circuitry. article_processing_charge: No article_type: original author: - first_name: Tim P full_name: Vogels, Tim P id: CB6FF8D2-008F-11EA-8E08-2637E6697425 last_name: Vogels orcid: 0000-0003-3295-6181 - first_name: H. full_name: Sprekeler, H. last_name: Sprekeler - first_name: F. full_name: Zenke, F. last_name: Zenke - first_name: C. full_name: Clopath, C. last_name: Clopath - first_name: W. full_name: Gerstner, W. last_name: Gerstner citation: ama: Vogels TP, Sprekeler H, Zenke F, Clopath C, Gerstner W. Inhibitory plasticity balances excitation and inhibition in sensory pathways and memory networks. Science. 2011;334(6062):1569-1573. doi:10.1126/science.1211095 apa: Vogels, T. P., Sprekeler, H., Zenke, F., Clopath, C., & Gerstner, W. (2011). Inhibitory plasticity balances excitation and inhibition in sensory pathways and memory networks. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1211095 chicago: Vogels, Tim P, H. Sprekeler, F. Zenke, C. Clopath, and W. Gerstner. “Inhibitory Plasticity Balances Excitation and Inhibition in Sensory Pathways and Memory Networks.” Science. American Association for the Advancement of Science, 2011. https://doi.org/10.1126/science.1211095. ieee: T. P. Vogels, H. Sprekeler, F. Zenke, C. Clopath, and W. Gerstner, “Inhibitory plasticity balances excitation and inhibition in sensory pathways and memory networks,” Science, vol. 334, no. 6062. American Association for the Advancement of Science, pp. 1569–1573, 2011. ista: Vogels TP, Sprekeler H, Zenke F, Clopath C, Gerstner W. 2011. Inhibitory plasticity balances excitation and inhibition in sensory pathways and memory networks. Science. 334(6062), 1569–1573. mla: Vogels, Tim P., et al. “Inhibitory Plasticity Balances Excitation and Inhibition in Sensory Pathways and Memory Networks.” Science, vol. 334, no. 6062, American Association for the Advancement of Science, 2011, pp. 1569–73, doi:10.1126/science.1211095. short: T.P. Vogels, H. Sprekeler, F. Zenke, C. Clopath, W. Gerstner, Science 334 (2011) 1569–1573. date_created: 2020-06-30T13:26:17Z date_published: 2011-12-16T00:00:00Z date_updated: 2021-06-02T14:57:22Z day: '16' doi: 10.1126/science.1211095 extern: '1' external_id: pmid: - '22075724' intvolume: ' 334' issue: '6062' language: - iso: eng month: '12' oa_version: None page: 1569-1573 pmid: 1 publication: Science publication_identifier: issn: - 0036-8075 - 1095-9203 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' related_material: link: - relation: erratum url: https://doi.org/10.1126/science.336.6083.802-c scopus_import: '1' status: public title: Inhibitory plasticity balances excitation and inhibition in sensory pathways and memory networks type: journal_article user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425 volume: 334 year: '2011' ... --- _id: '9452' abstract: - lang: eng text: Eukaryotic cytosine methylation represses transcription but also occurs in the bodies of active genes, and the extent of methylation biology conservation is unclear. We quantified DNA methylation in 17 eukaryotic genomes and found that gene body methylation is conserved between plants and animals, whereas selective methylation of transposons is not. We show that methylation of plant transposons in the CHG context extends to green algae and that exclusion of histone H2A.Z from methylated DNA is conserved between plants and animals, and we present evidence for RNA-directed DNA methylation of fungal genes. Our data demonstrate that extant DNA methylation systems are mosaics of conserved and derived features, and indicate that gene body methylation is an ancient property of eukaryotic genomes. article_processing_charge: No article_type: original author: - first_name: 'Assaf ' full_name: 'Zemach, Assaf ' last_name: Zemach - first_name: Ivy E. full_name: McDaniel, Ivy E. last_name: McDaniel - first_name: Pedro full_name: Silva, Pedro last_name: Silva - first_name: Daniel full_name: Zilberman, Daniel id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1 last_name: Zilberman orcid: 0000-0002-0123-8649 citation: ama: Zemach A, McDaniel IE, Silva P, Zilberman D. Genome-wide evolutionary analysis of eukaryotic DNA methylation. Science. 2010;328(5980):916-919. doi:10.1126/science.1186366 apa: Zemach, A., McDaniel, I. E., Silva, P., & Zilberman, D. (2010). Genome-wide evolutionary analysis of eukaryotic DNA methylation. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1186366 chicago: Zemach, Assaf , Ivy E. McDaniel, Pedro Silva, and Daniel Zilberman. “Genome-Wide Evolutionary Analysis of Eukaryotic DNA Methylation.” Science. American Association for the Advancement of Science, 2010. https://doi.org/10.1126/science.1186366. ieee: A. Zemach, I. E. McDaniel, P. Silva, and D. Zilberman, “Genome-wide evolutionary analysis of eukaryotic DNA methylation,” Science, vol. 328, no. 5980. American Association for the Advancement of Science, pp. 916–919, 2010. ista: Zemach A, McDaniel IE, Silva P, Zilberman D. 2010. Genome-wide evolutionary analysis of eukaryotic DNA methylation. Science. 328(5980), 916–919. mla: Zemach, Assaf, et al. “Genome-Wide Evolutionary Analysis of Eukaryotic DNA Methylation.” Science, vol. 328, no. 5980, American Association for the Advancement of Science, 2010, pp. 916–19, doi:10.1126/science.1186366. short: A. Zemach, I.E. McDaniel, P. Silva, D. Zilberman, Science 328 (2010) 916–919. date_created: 2021-06-04T08:26:08Z date_published: 2010-05-14T00:00:00Z date_updated: 2021-12-14T08:35:37Z day: '14' department: - _id: DaZi doi: 10.1126/science.1186366 extern: '1' external_id: pmid: - '20395474 ' intvolume: ' 328' issue: '5980' keyword: - Multidisciplinary language: - iso: eng month: '05' oa_version: None page: 916-919 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Genome-wide evolutionary analysis of eukaryotic DNA methylation type: journal_article user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9 volume: 328 year: '2010' ... --- _id: '9453' abstract: - lang: eng text: Parent-of-origin-specific (imprinted) gene expression is regulated in Arabidopsis thaliana endosperm by cytosine demethylation of the maternal genome mediated by the DNA glycosylase DEMETER, but the extent of the methylation changes is not known. Here, we show that virtually the entire endosperm genome is demethylated, coupled with extensive local non-CG hypermethylation of small interfering RNA–targeted sequences. Mutation of DEMETER partially restores endosperm CG methylation to levels found in other tissues, indicating that CG demethylation is specific to maternal sequences. Endosperm demethylation is accompanied by CHH hypermethylation of embryo transposable elements. Our findings demonstrate extensive reconfiguration of the endosperm methylation landscape that likely reinforces transposon silencing in the embryo. article_processing_charge: No article_type: original author: - first_name: Tzung-Fu full_name: Hsieh, Tzung-Fu last_name: Hsieh - first_name: Christian A. full_name: Ibarra, Christian A. last_name: Ibarra - first_name: Pedro full_name: Silva, Pedro last_name: Silva - first_name: Assaf full_name: Zemach, Assaf last_name: Zemach - first_name: Leor full_name: Eshed-Williams, Leor last_name: Eshed-Williams - first_name: Robert L. full_name: Fischer, Robert L. last_name: Fischer - first_name: Daniel full_name: Zilberman, Daniel id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1 last_name: Zilberman orcid: 0000-0002-0123-8649 citation: ama: Hsieh T-F, Ibarra CA, Silva P, et al. Genome-wide demethylation of Arabidopsis endosperm. Science. 2009;324(5933):1451-1454. doi:10.1126/science.1172417 apa: Hsieh, T.-F., Ibarra, C. A., Silva, P., Zemach, A., Eshed-Williams, L., Fischer, R. L., & Zilberman, D. (2009). Genome-wide demethylation of Arabidopsis endosperm. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1172417 chicago: Hsieh, Tzung-Fu, Christian A. Ibarra, Pedro Silva, Assaf Zemach, Leor Eshed-Williams, Robert L. Fischer, and Daniel Zilberman. “Genome-Wide Demethylation of Arabidopsis Endosperm.” Science. American Association for the Advancement of Science, 2009. https://doi.org/10.1126/science.1172417. ieee: T.-F. Hsieh et al., “Genome-wide demethylation of Arabidopsis endosperm,” Science, vol. 324, no. 5933. American Association for the Advancement of Science, pp. 1451–1454, 2009. ista: Hsieh T-F, Ibarra CA, Silva P, Zemach A, Eshed-Williams L, Fischer RL, Zilberman D. 2009. Genome-wide demethylation of Arabidopsis endosperm. Science. 324(5933), 1451–1454. mla: Hsieh, Tzung-Fu, et al. “Genome-Wide Demethylation of Arabidopsis Endosperm.” Science, vol. 324, no. 5933, American Association for the Advancement of Science, 2009, pp. 1451–54, doi:10.1126/science.1172417. short: T.-F. Hsieh, C.A. Ibarra, P. Silva, A. Zemach, L. Eshed-Williams, R.L. Fischer, D. Zilberman, Science 324 (2009) 1451–1454. date_created: 2021-06-04T08:55:41Z date_published: 2009-06-12T00:00:00Z date_updated: 2021-12-14T08:53:26Z day: '12' department: - _id: DaZi doi: 10.1126/science.1172417 extern: '1' external_id: pmid: - '19520962' intvolume: ' 324' issue: '5933' keyword: - Multidisciplinary language: - iso: eng main_file_link: - open_access: '1' url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044190/ month: '06' oa: 1 oa_version: Submitted Version page: 1451-1454 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Genome-wide demethylation of Arabidopsis endosperm type: journal_article user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9 volume: 324 year: '2009' ... --- _id: '11884' abstract: - lang: eng text: About 20% of the world's population uses the Web, and a large majority thereof uses Web search engines to find information. As a result, many Web researchers are devoting much effort to improving the speed and capability of search technology. article_processing_charge: No article_type: review author: - first_name: Monika H full_name: Henzinger, Monika H id: 540c9bbd-f2de-11ec-812d-d04a5be85630 last_name: Henzinger orcid: 0000-0002-5008-6530 citation: ama: Henzinger MH. Search technologies for the internet. Science. 2007;317(5837):468-471. doi:10.1126/science.1126557 apa: Henzinger, M. H. (2007). Search technologies for the internet. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1126557 chicago: Henzinger, Monika H. “Search Technologies for the Internet.” Science. American Association for the Advancement of Science, 2007. https://doi.org/10.1126/science.1126557. ieee: M. H. Henzinger, “Search technologies for the internet,” Science, vol. 317, no. 5837. American Association for the Advancement of Science, pp. 468–471, 2007. ista: Henzinger MH. 2007. Search technologies for the internet. Science. 317(5837), 468–471. mla: Henzinger, Monika H. “Search Technologies for the Internet.” Science, vol. 317, no. 5837, American Association for the Advancement of Science, 2007, pp. 468–71, doi:10.1126/science.1126557. short: M.H. Henzinger, Science 317 (2007) 468–471. date_created: 2022-08-17T07:30:07Z date_published: 2007-07-27T00:00:00Z date_updated: 2023-02-17T14:07:49Z day: '27' doi: 10.1126/science.1126557 extern: '1' external_id: pmid: - '17656714' intvolume: ' 317' issue: '5837' language: - iso: eng month: '07' oa_version: None page: 468-471 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Search technologies for the internet type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 317 year: '2007' ... --- _id: '13427' abstract: - lang: eng text: Deformable, spherical aggregates of metal nanoparticles connected by long-chain dithiol ligands self-assemble into nanostructured materials of macroscopic dimensions. These materials are plastic and moldable against arbitrarily shaped masters and can be thermally hardened into polycrystalline metal structures of controllable porosity. In addition, in both plastic and hardened states, the assemblies are electrically conductive and exhibit Ohmic characteristics down to ∼20 volts per meter. The self-assembly method leading to such materials is applicable both to pure metals and to bimetallic structures of various elemental compositions. article_processing_charge: No article_type: letter_note author: - first_name: Rafal full_name: Klajn, Rafal id: 8e84690e-1e48-11ed-a02b-a1e6fb8bb53b last_name: Klajn - first_name: Kyle J. M. full_name: Bishop, Kyle J. M. last_name: Bishop - first_name: Marcin full_name: Fialkowski, Marcin last_name: Fialkowski - first_name: Maciej full_name: Paszewski, Maciej last_name: Paszewski - first_name: Christopher J. full_name: Campbell, Christopher J. last_name: Campbell - first_name: Timothy P. full_name: Gray, Timothy P. last_name: Gray - first_name: Bartosz A. full_name: Grzybowski, Bartosz A. last_name: Grzybowski citation: ama: Klajn R, Bishop KJM, Fialkowski M, et al. Plastic and moldable metals by self-assembly of sticky nanoparticle aggregates. Science. 2007;316(5822):261-264. doi:10.1126/science.1139131 apa: Klajn, R., Bishop, K. J. M., Fialkowski, M., Paszewski, M., Campbell, C. J., Gray, T. P., & Grzybowski, B. A. (2007). Plastic and moldable metals by self-assembly of sticky nanoparticle aggregates. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1139131 chicago: Klajn, Rafal, Kyle J. M. Bishop, Marcin Fialkowski, Maciej Paszewski, Christopher J. Campbell, Timothy P. Gray, and Bartosz A. Grzybowski. “Plastic and Moldable Metals by Self-Assembly of Sticky Nanoparticle Aggregates.” Science. American Association for the Advancement of Science, 2007. https://doi.org/10.1126/science.1139131. ieee: R. Klajn et al., “Plastic and moldable metals by self-assembly of sticky nanoparticle aggregates,” Science, vol. 316, no. 5822. American Association for the Advancement of Science, pp. 261–264, 2007. ista: Klajn R, Bishop KJM, Fialkowski M, Paszewski M, Campbell CJ, Gray TP, Grzybowski BA. 2007. Plastic and moldable metals by self-assembly of sticky nanoparticle aggregates. Science. 316(5822), 261–264. mla: Klajn, Rafal, et al. “Plastic and Moldable Metals by Self-Assembly of Sticky Nanoparticle Aggregates.” Science, vol. 316, no. 5822, American Association for the Advancement of Science, 2007, pp. 261–64, doi:10.1126/science.1139131. short: R. Klajn, K.J.M. Bishop, M. Fialkowski, M. Paszewski, C.J. Campbell, T.P. Gray, B.A. Grzybowski, Science 316 (2007) 261–264. date_created: 2023-08-01T10:36:08Z date_published: 2007-04-13T00:00:00Z date_updated: 2023-08-08T11:28:29Z day: '13' doi: 10.1126/science.1139131 extern: '1' external_id: pmid: - '17431176' intvolume: ' 316' issue: '5822' keyword: - Multidisciplinary language: - iso: eng month: '04' oa_version: None page: 261-264 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Plastic and moldable metals by self-assembly of sticky nanoparticle aggregates type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 316 year: '2007' ... --- _id: '11118' abstract: - lang: eng text: Nuclear pore complexes are multiprotein channels that span the double lipid bilayer of the nuclear envelope. How new pores are inserted into the intact nuclear envelope of proliferating and differentiating eukaryotic cells is unknown. We found that the Nup107-160 complex was incorporated into assembly sites in the nuclear envelope from both the nucleoplasmic and the cytoplasmic sides. Nuclear pore insertion required the generation of Ran guanosine triphosphate in the nuclear and cytoplasmic compartments. Newly formed nuclear pore complexes did not contain structural components of preexisting pores, suggesting that they can form de novo. article_processing_charge: No article_type: original author: - first_name: Maximiliano A. full_name: D'Angelo, Maximiliano A. last_name: D'Angelo - first_name: Daniel J. full_name: Anderson, Daniel J. last_name: Anderson - first_name: Erin full_name: Richard, Erin last_name: Richard - first_name: Martin W full_name: HETZER, Martin W id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed last_name: HETZER orcid: 0000-0002-2111-992X citation: ama: D’Angelo MA, Anderson DJ, Richard E, Hetzer M. Nuclear pores form de novo from both sides of the nuclear envelope. Science. 2006;312(5772):440-443. doi:10.1126/science.1124196 apa: D’Angelo, M. A., Anderson, D. J., Richard, E., & Hetzer, M. (2006). Nuclear pores form de novo from both sides of the nuclear envelope. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1124196 chicago: D’Angelo, Maximiliano A., Daniel J. Anderson, Erin Richard, and Martin Hetzer. “Nuclear Pores Form de Novo from Both Sides of the Nuclear Envelope.” Science. American Association for the Advancement of Science, 2006. https://doi.org/10.1126/science.1124196. ieee: M. A. D’Angelo, D. J. Anderson, E. Richard, and M. Hetzer, “Nuclear pores form de novo from both sides of the nuclear envelope,” Science, vol. 312, no. 5772. American Association for the Advancement of Science, pp. 440–443, 2006. ista: D’Angelo MA, Anderson DJ, Richard E, Hetzer M. 2006. Nuclear pores form de novo from both sides of the nuclear envelope. Science. 312(5772), 440–443. mla: D’Angelo, Maximiliano A., et al. “Nuclear Pores Form de Novo from Both Sides of the Nuclear Envelope.” Science, vol. 312, no. 5772, American Association for the Advancement of Science, 2006, pp. 440–43, doi:10.1126/science.1124196. short: M.A. D’Angelo, D.J. Anderson, E. Richard, M. Hetzer, Science 312 (2006) 440–443. date_created: 2022-04-07T07:56:32Z date_published: 2006-04-21T00:00:00Z date_updated: 2022-07-18T08:57:04Z day: '21' doi: 10.1126/science.1124196 extern: '1' external_id: pmid: - '16627745' intvolume: ' 312' issue: '5772' keyword: - Multidisciplinary language: - iso: eng month: '04' oa_version: None page: 440-443 pmid: 1 publication: Science publication_identifier: issn: - 0036-8075 - 1095-9203 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Nuclear pores form de novo from both sides of the nuclear envelope type: journal_article user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd volume: 312 year: '2006' ... --- _id: '9454' article_processing_charge: No article_type: original author: - first_name: Simon W.-L. full_name: Chan, Simon W.-L. last_name: Chan - first_name: Daniel full_name: Zilberman, Daniel id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1 last_name: Zilberman orcid: 0000-0002-0123-8649 - first_name: ' Zhixin' full_name: Xie, Zhixin last_name: Xie - first_name: ' Lisa K.' full_name: Johansen, Lisa K. last_name: Johansen - first_name: James C. full_name: Carrington, James C. last_name: Carrington - first_name: Steven E. full_name: Jacobsen, Steven E. last_name: Jacobsen citation: ama: Chan SW-L, Zilberman D, Xie Zhixin, Johansen Lisa K., Carrington JC, Jacobsen SE. RNA silencing genes control de novo DNA methylation. Science. 2004;303(5662):1336. doi:10.1126/science.1095989 apa: Chan, S. W.-L., Zilberman, D., Xie, Zhixin, Johansen, Lisa K., Carrington, J. C., & Jacobsen, S. E. (2004). RNA silencing genes control de novo DNA methylation. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1095989 chicago: Chan, Simon W.-L., Daniel Zilberman, Zhixin Xie, Lisa K. Johansen, James C. Carrington, and Steven E. Jacobsen. “RNA Silencing Genes Control de Novo DNA Methylation.” Science. American Association for the Advancement of Science, 2004. https://doi.org/10.1126/science.1095989. ieee: S. W.-L. Chan, D. Zilberman, Zhixin Xie, Lisa K. Johansen, J. C. Carrington, and S. E. Jacobsen, “RNA silencing genes control de novo DNA methylation,” Science, vol. 303, no. 5662. American Association for the Advancement of Science, p. 1336, 2004. ista: Chan SW-L, Zilberman D, Xie Zhixin, Johansen Lisa K., Carrington JC, Jacobsen SE. 2004. RNA silencing genes control de novo DNA methylation. Science. 303(5662), 1336. mla: Chan, Simon W. L., et al. “RNA Silencing Genes Control de Novo DNA Methylation.” Science, vol. 303, no. 5662, American Association for the Advancement of Science, 2004, p. 1336, doi:10.1126/science.1095989. short: S.W.-L. Chan, D. Zilberman, Zhixin Xie, Lisa K. Johansen, J.C. Carrington, S.E. Jacobsen, Science 303 (2004) 1336. date_created: 2021-06-04T11:12:35Z date_published: 2004-02-27T00:00:00Z date_updated: 2021-12-14T09:13:53Z day: '27' department: - _id: DaZi doi: 10.1126/science.1095989 extern: '1' external_id: pmid: - '14988555' intvolume: ' 303' issue: '5662' keyword: - Multidisciplinary language: - iso: eng month: '02' oa_version: None page: '1336' pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: RNA silencing genes control de novo DNA methylation type: journal_article user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9 volume: 303 year: '2004' ... --- _id: '7706' abstract: - lang: eng text: 'The Sir2 deacetylase modulates organismal life-span in various species. However, the molecular mechanisms by which Sir2 increases longevity are largely unknown. We show that in mammalian cells, the Sir2 homolog SIRT1 appears to control the cellular response to stress by regulating the FOXO family of Forkhead transcription factors, a family of proteins that function as sensors of the insulin signaling pathway and as regulators of organismal longevity. SIRT1 and the FOXO transcription factor FOXO3 formed a complex in cells in response to oxidative stress, and SIRT1 deacetylated FOXO3 in vitro and within cells. SIRT1 had a dual effect on FOXO3 function: SIRT1 increased FOXO3''s ability to induce cell cycle arrest and resistance to oxidative stress but inhibited FOXO3''s ability to induce cell death. Thus, one way in which members of the Sir2 family of proteins may increase organismal longevity is by tipping FOXO-dependent responses away from apoptosis and toward stress resistance.' article_processing_charge: No article_type: original author: - first_name: Anne full_name: Brunet, Anne last_name: Brunet - first_name: Lora Beatrice Jaeger full_name: Sweeney, Lora Beatrice Jaeger id: 56BE8254-C4F0-11E9-8E45-0B23E6697425 last_name: Sweeney orcid: 0000-0001-9242-5601 - first_name: 'J Fitzhugh ' full_name: 'Sturgill, J Fitzhugh ' last_name: Sturgill - first_name: Katrin full_name: Chua, Katrin last_name: Chua - first_name: Paul full_name: Greer, Paul last_name: Greer - first_name: Yingxi full_name: Lin, Yingxi last_name: Lin - first_name: Hien full_name: Tran, Hien last_name: Tran - first_name: Sarah full_name: Ross, Sarah last_name: Ross - first_name: Raul full_name: Mostoslavsky, Raul last_name: Mostoslavsky - first_name: Haim full_name: Cohen, Haim last_name: Cohen - first_name: Linda full_name: Hu, Linda last_name: Hu - first_name: Hwei-Ling full_name: Chen, Hwei-Ling last_name: Chen - first_name: Mark full_name: Jedrychowski, Mark last_name: Jedrychowski - first_name: Steven full_name: Gygi, Steven last_name: Gygi - first_name: David full_name: Sinclair, David last_name: Sinclair - first_name: Frederick full_name: Alt, Frederick last_name: Alt - first_name: Michael full_name: Greenberg, Michael last_name: Greenberg citation: ama: Brunet A, Sweeney LB, Sturgill JF, et al. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science. 2004;303(5666):2011-2015. doi:10.1126/science.1094637 apa: Brunet, A., Sweeney, L. B., Sturgill, J. F., Chua, K., Greer, P., Lin, Y., … Greenberg, M. (2004). Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1094637 chicago: Brunet, Anne, Lora B. Sweeney, J Fitzhugh Sturgill, Katrin Chua, Paul Greer, Yingxi Lin, Hien Tran, et al. “Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase.” Science. American Association for the Advancement of Science, 2004. https://doi.org/10.1126/science.1094637. ieee: A. Brunet et al., “Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase,” Science, vol. 303, no. 5666. American Association for the Advancement of Science, pp. 2011–2015, 2004. ista: Brunet A, Sweeney LB, Sturgill JF, Chua K, Greer P, Lin Y, Tran H, Ross S, Mostoslavsky R, Cohen H, Hu L, Chen H-L, Jedrychowski M, Gygi S, Sinclair D, Alt F, Greenberg M. 2004. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science. 303(5666), 2011–2015. mla: Brunet, Anne, et al. “Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase.” Science, vol. 303, no. 5666, American Association for the Advancement of Science, 2004, pp. 2011–15, doi:10.1126/science.1094637. short: A. Brunet, L.B. Sweeney, J.F. Sturgill, K. Chua, P. Greer, Y. Lin, H. Tran, S. Ross, R. Mostoslavsky, H. Cohen, L. Hu, H.-L. Chen, M. Jedrychowski, S. Gygi, D. Sinclair, F. Alt, M. Greenberg, Science 303 (2004) 2011–2015. date_created: 2020-04-30T10:37:41Z date_published: 2004-03-26T00:00:00Z date_updated: 2024-01-31T10:14:17Z day: '26' doi: 10.1126/science.1094637 extern: '1' intvolume: ' 303' issue: '5666' language: - iso: eng month: '03' oa_version: None page: 2011-2015 publication: Science publication_identifier: issn: - 0036-8075 - 1095-9203 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' status: public title: Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 303 year: '2004' ... --- _id: '9455' abstract: - lang: eng text: Proteins of the ARGONAUTE family are important in diverse posttranscriptional RNA-mediated gene-silencing systems as well as in transcriptional gene silencing in Drosophila and fission yeast and in programmed DNA elimination in Tetrahymena. We cloned ARGONAUTE4 (AGO4) from a screen for mutants that suppress silencing of the Arabidopsis SUPERMAN(SUP) gene. The ago4-1 mutant reactivated silentSUP alleles and decreased CpNpG and asymmetric DNA methylation as well as histone H3 lysine-9 methylation. In addition,ago4-1 blocked histone and DNA methylation and the accumulation of 25-nucleotide small interfering RNAs (siRNAs) that correspond to the retroelement AtSN1. These results suggest that AGO4 and long siRNAs direct chromatin modifications, including histone methylation and non-CpG DNA methylation. article_processing_charge: No article_type: original author: - first_name: Daniel full_name: Zilberman, Daniel id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1 last_name: Zilberman orcid: 0000-0002-0123-8649 - first_name: ' Xiaofeng' full_name: Cao, Xiaofeng last_name: Cao - first_name: Steven E. full_name: Jacobsen, Steven E. last_name: Jacobsen citation: ama: Zilberman D, Cao Xiaofeng, Jacobsen SE. ARGONAUTE4 control of locus-specific siRNA accumulation and DNA and histone methylation. Science. 2003;299(5607):716-719. doi:10.1126/science.1079695 apa: Zilberman, D., Cao, Xiaofeng, & Jacobsen, S. E. (2003). ARGONAUTE4 control of locus-specific siRNA accumulation and DNA and histone methylation. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1079695 chicago: Zilberman, Daniel, Xiaofeng Cao, and Steven E. Jacobsen. “ARGONAUTE4 Control of Locus-Specific SiRNA Accumulation and DNA and Histone Methylation.” Science. American Association for the Advancement of Science, 2003. https://doi.org/10.1126/science.1079695. ieee: D. Zilberman, Xiaofeng Cao, and S. E. Jacobsen, “ARGONAUTE4 control of locus-specific siRNA accumulation and DNA and histone methylation,” Science, vol. 299, no. 5607. American Association for the Advancement of Science, pp. 716–719, 2003. ista: Zilberman D, Cao Xiaofeng, Jacobsen SE. 2003. ARGONAUTE4 control of locus-specific siRNA accumulation and DNA and histone methylation. Science. 299(5607), 716–719. mla: Zilberman, Daniel, et al. “ARGONAUTE4 Control of Locus-Specific SiRNA Accumulation and DNA and Histone Methylation.” Science, vol. 299, no. 5607, American Association for the Advancement of Science, 2003, pp. 716–19, doi:10.1126/science.1079695. short: D. Zilberman, Xiaofeng Cao, S.E. Jacobsen, Science 299 (2003) 716–719. date_created: 2021-06-04T11:26:26Z date_published: 2003-01-31T00:00:00Z date_updated: 2021-12-14T08:43:30Z day: '31' department: - _id: DaZi doi: 10.1126/science.1079695 extern: '1' external_id: pmid: - '12522258' intvolume: ' 299' issue: '5607' keyword: - Multidisciplinary language: - iso: eng month: '01' oa_version: None page: 716-719 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: ARGONAUTE4 control of locus-specific siRNA accumulation and DNA and histone methylation type: journal_article user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9 volume: 299 year: '2003' ... --- _id: '4255' abstract: - lang: eng text: 'Humans and their closest evolutionary relatives, the chimpanzees, differ in ∼1.24% of their genomic DNA sequences. The fraction of these changes accumulated during the speciation processes that have separated the two lineages may be of special relevance in understanding the basis of their differences. We analyzed human and chimpanzee sequence data to search for the patterns of divergence and polymorphism predicted by a theoretical model of speciation. According to the model, positively selected changes should accumulate in chromosomes that present fixed structural differences, such as inversions, between the two species. Protein evolution was more than 2.2 times faster in chromosomes that had undergone structural rearrangements compared with colinear chromosomes. Also, nucleotide variability is slightly lower in rearranged chromosomes. These patterns of divergence and polymorphism may be, at least in part, the molecular footprint of speciation events in the human and chimpanzee lineages. ' article_processing_charge: No article_type: original author: - first_name: Arcadio full_name: Navarro, Arcadio last_name: Navarro - first_name: Nicholas H full_name: Barton, Nicholas H id: 4880FE40-F248-11E8-B48F-1D18A9856A87 last_name: Barton orcid: 0000-0002-8548-5240 citation: ama: Navarro A, Barton NH. Chromosomal speciation and molecular divergence -- Accelerated evolution in rearranged chromosomes. Science. 2003;300(5617):321-324. doi:10.1126/science.1080600 apa: Navarro, A., & Barton, N. H. (2003). Chromosomal speciation and molecular divergence -- Accelerated evolution in rearranged chromosomes. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1080600 chicago: Navarro, Arcadio, and Nicholas H Barton. “Chromosomal Speciation and Molecular Divergence -- Accelerated Evolution in Rearranged Chromosomes.” Science. American Association for the Advancement of Science, 2003. https://doi.org/10.1126/science.1080600 . ieee: A. Navarro and N. H. Barton, “Chromosomal speciation and molecular divergence -- Accelerated evolution in rearranged chromosomes,” Science, vol. 300, no. 5617. American Association for the Advancement of Science, pp. 321–324, 2003. ista: Navarro A, Barton NH. 2003. Chromosomal speciation and molecular divergence -- Accelerated evolution in rearranged chromosomes. Science. 300(5617), 321–324. mla: Navarro, Arcadio, and Nicholas H. Barton. “Chromosomal Speciation and Molecular Divergence -- Accelerated Evolution in Rearranged Chromosomes.” Science, vol. 300, no. 5617, American Association for the Advancement of Science, 2003, pp. 321–24, doi:10.1126/science.1080600 . short: A. Navarro, N.H. Barton, Science 300 (2003) 321–324. date_created: 2018-12-11T12:07:53Z date_published: 2003-04-11T00:00:00Z date_updated: 2024-02-26T13:37:51Z day: '11' doi: '10.1126/science.1080600 ' extern: '1' external_id: pmid: - ' 12690198' intvolume: ' 300' issue: '5617' language: - iso: eng month: '04' oa_version: None page: 321 - 324 pmid: 1 publication: Science publication_identifier: issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science publist_id: '1841' quality_controlled: '1' scopus_import: '1' status: public title: Chromosomal speciation and molecular divergence -- Accelerated evolution in rearranged chromosomes type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 300 year: '2003' ... --- _id: '3757' abstract: - lang: eng text: A central problem in biology is determining how genes interact as parts of functional networks. Creation and analysis of synthetic networks, composed of well-characterized genetic elements, provide a framework for theoretical modeling. Here, with the use of a combinatorial method, a library of networks with varying connectivity was generated in Escherichia coli. These networks were composed of genes encoding the transcriptional regulators Lacl, TetR, and lambda Cl, as well as the corresponding promoters. They displayed phenotypic behaviors resembling binary logical circuits, with two chemical “inputs” and a fluorescent protein “output.” Within this simple system, diverse computational functions arose through changes in network connectivity. Combinatorial synthesis provides an alternative approach for studying biological networks, as well as an efficient method for producing diverse phenotypes in vivo. article_processing_charge: No article_type: original author: - first_name: Calin C full_name: Guet, Calin C id: 47F8433E-F248-11E8-B48F-1D18A9856A87 last_name: Guet orcid: 0000-0001-6220-2052 - first_name: Michael full_name: Elowitz, Michael last_name: Elowitz - first_name: Weihong full_name: Hsing, Weihong last_name: Hsing - first_name: Stanislas full_name: Leibler, Stanislas last_name: Leibler citation: ama: Guet CC, Elowitz M, Hsing W, Leibler S. Combinatorial synthesis of genetic networks. Science. 2002;296(5572):1466-1470. doi:10.1126/science.1067407 apa: Guet, C. C., Elowitz, M., Hsing, W., & Leibler, S. (2002). Combinatorial synthesis of genetic networks. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1067407 chicago: Guet, Calin C, Michael Elowitz, Weihong Hsing, and Stanislas Leibler. “Combinatorial Synthesis of Genetic Networks.” Science. American Association for the Advancement of Science, 2002. https://doi.org/10.1126/science.1067407. ieee: C. C. Guet, M. Elowitz, W. Hsing, and S. Leibler, “Combinatorial synthesis of genetic networks,” Science, vol. 296, no. 5572. American Association for the Advancement of Science, pp. 1466–1470, 2002. ista: Guet CC, Elowitz M, Hsing W, Leibler S. 2002. Combinatorial synthesis of genetic networks. Science. 296(5572), 1466–1470. mla: Guet, Calin C., et al. “Combinatorial Synthesis of Genetic Networks.” Science, vol. 296, no. 5572, American Association for the Advancement of Science, 2002, pp. 1466–70, doi:10.1126/science.1067407. short: C.C. Guet, M. Elowitz, W. Hsing, S. Leibler, Science 296 (2002) 1466–1470. date_created: 2018-12-11T12:05:00Z date_published: 2002-05-24T00:00:00Z date_updated: 2023-07-11T12:48:53Z day: '24' doi: 10.1126/science.1067407 extern: '1' external_id: pmid: - '12029133' intvolume: ' 296' issue: '5572' language: - iso: eng month: '05' oa_version: None page: 1466 - 1470 pmid: 1 publication: Science publication_identifier: issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science publist_id: '2471' quality_controlled: '1' scopus_import: '1' status: public title: Combinatorial synthesis of genetic networks type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 296 year: '2002' ... --- _id: '9444' abstract: - lang: eng text: Epigenetic silenced alleles of the Arabidopsis SUPERMANlocus (the clark kent alleles) are associated with dense hypermethylation at noncanonical cytosines (CpXpG and asymmetric sites, where X = A, T, C, or G). A genetic screen for suppressors of a hypermethylated clark kent mutant identified nine loss-of-function alleles of CHROMOMETHYLASE3(CMT3), a novel cytosine methyltransferase homolog. These cmt3 mutants display a wild-type morphology but exhibit decreased CpXpG methylation of the SUP gene and of other sequences throughout the genome. They also show reactivated expression of endogenous retrotransposon sequences. These results show that a non-CpG DNA methyltransferase is responsible for maintaining epigenetic gene silencing. article_processing_charge: No article_type: original author: - first_name: A. M. full_name: Lindroth, A. M. last_name: Lindroth - first_name: Xiaofeng full_name: Cao, Xiaofeng last_name: Cao - first_name: James P. full_name: Jackson, James P. last_name: Jackson - first_name: Daniel full_name: Zilberman, Daniel id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1 last_name: Zilberman orcid: 0000-0002-0123-8649 - first_name: Claire M. full_name: McCallum, Claire M. last_name: McCallum - first_name: Steven full_name: Henikoff, Steven last_name: Henikoff - first_name: Steven E. full_name: Jacobsen, Steven E. last_name: Jacobsen citation: ama: Lindroth AM, Cao X, Jackson JP, et al. Requirement of CHROMOMETHYLASE3 for maintenance of CpXpG methylation. Science. 2001;292(5524):2077-2080. doi:10.1126/science.1059745 apa: Lindroth, A. M., Cao, X., Jackson, J. P., Zilberman, D., McCallum, C. M., Henikoff, S., & Jacobsen, S. E. (2001). Requirement of CHROMOMETHYLASE3 for maintenance of CpXpG methylation. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1059745 chicago: Lindroth, A. M., Xiaofeng Cao, James P. Jackson, Daniel Zilberman, Claire M. McCallum, Steven Henikoff, and Steven E. Jacobsen. “Requirement of CHROMOMETHYLASE3 for Maintenance of CpXpG Methylation.” Science. American Association for the Advancement of Science, 2001. https://doi.org/10.1126/science.1059745. ieee: A. M. Lindroth et al., “Requirement of CHROMOMETHYLASE3 for maintenance of CpXpG methylation,” Science, vol. 292, no. 5524. American Association for the Advancement of Science, pp. 2077–2080, 2001. ista: Lindroth AM, Cao X, Jackson JP, Zilberman D, McCallum CM, Henikoff S, Jacobsen SE. 2001. Requirement of CHROMOMETHYLASE3 for maintenance of CpXpG methylation. Science. 292(5524), 2077–2080. mla: Lindroth, A. M., et al. “Requirement of CHROMOMETHYLASE3 for Maintenance of CpXpG Methylation.” Science, vol. 292, no. 5524, American Association for the Advancement of Science, 2001, pp. 2077–80, doi:10.1126/science.1059745. short: A.M. Lindroth, X. Cao, J.P. Jackson, D. Zilberman, C.M. McCallum, S. Henikoff, S.E. Jacobsen, Science 292 (2001) 2077–2080. date_created: 2021-06-02T13:35:16Z date_published: 2001-06-15T00:00:00Z date_updated: 2021-12-14T08:40:32Z day: '15' department: - _id: DaZi doi: 10.1126/science.1059745 extern: '1' external_id: pmid: - '11349138' intvolume: ' 292' issue: '5524' keyword: - Multidisciplinary language: - iso: eng month: '06' oa_version: None page: 2077-2080 pmid: 1 publication: Science publication_identifier: eissn: - 1095-9203 issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science quality_controlled: '1' scopus_import: '1' status: public title: Requirement of CHROMOMETHYLASE3 for maintenance of CpXpG methylation type: journal_article user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9 volume: 292 year: '2001' ... --- _id: '3438' abstract: - lang: eng text: As a discipline, phylogenetics is becoming transformed by a flood of molecular data. These data allow broad questions to be asked about the history of life, but also present difficult statistical and computational problems. Bayesian inference of phylogeny brings a new perspective to a number of outstanding issues in evolutionary biology, including the analysis of large phylogenetic trees and complex evolutionary models and the detection of the footprint of natural selection in DNA sequences. article_processing_charge: No author: - first_name: John full_name: Huelsenbeck, John last_name: Huelsenbeck - first_name: Fredrik full_name: Ronquist, Fredrik last_name: Ronquist - first_name: Rasmus full_name: Nielsen, Rasmus last_name: Nielsen - first_name: Jonathan P full_name: Bollback, Jonathan P id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87 last_name: Bollback orcid: 0000-0002-4624-4612 citation: ama: Huelsenbeck J, Ronquist F, Nielsen R, Bollback JP. Bayesian inference of phylogeny and its impact on evolutionary biology. Science. 2001;294(5550):2310-2314. doi:10.1126/science.1065889 apa: Huelsenbeck, J., Ronquist, F., Nielsen, R., & Bollback, J. P. (2001). Bayesian inference of phylogeny and its impact on evolutionary biology. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1065889 chicago: Huelsenbeck, John, Fredrik Ronquist, Rasmus Nielsen, and Jonathan P Bollback. “Bayesian Inference of Phylogeny and Its Impact on Evolutionary Biology.” Science. American Association for the Advancement of Science, 2001. https://doi.org/10.1126/science.1065889. ieee: J. Huelsenbeck, F. Ronquist, R. Nielsen, and J. P. Bollback, “Bayesian inference of phylogeny and its impact on evolutionary biology,” Science, vol. 294, no. 5550. American Association for the Advancement of Science, pp. 2310–2314, 2001. ista: Huelsenbeck J, Ronquist F, Nielsen R, Bollback JP. 2001. Bayesian inference of phylogeny and its impact on evolutionary biology. Science. 294(5550), 2310–2314. mla: Huelsenbeck, John, et al. “Bayesian Inference of Phylogeny and Its Impact on Evolutionary Biology.” Science, vol. 294, no. 5550, American Association for the Advancement of Science, 2001, pp. 2310–14, doi:10.1126/science.1065889. short: J. Huelsenbeck, F. Ronquist, R. Nielsen, J.P. Bollback, Science 294 (2001) 2310–2314. date_created: 2018-12-11T12:03:20Z date_published: 2001-12-14T00:00:00Z date_updated: 2023-05-15T14:10:13Z day: '14' doi: 10.1126/science.1065889 extern: '1' external_id: pmid: - '11743192 ' intvolume: ' 294' issue: '5550' language: - iso: eng month: '12' oa_version: None page: 2310 - 2314 pmid: 1 publication: Science publication_identifier: issn: - 0036-8075 publication_status: published publisher: American Association for the Advancement of Science publist_id: '2962' quality_controlled: '1' status: public title: Bayesian inference of phylogeny and its impact on evolutionary biology type: journal_article user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17 volume: 294 year: '2001' ...