---
_id: '15166'
abstract:
- lang: eng
text: Reducing defects boosts room-temperature performance of a thermoelectric device
acknowledgement: The authors thank the Werner-Siemens-Stiftung and the Institute of
Science and Technology Austria for financial support.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Navita
full_name: Navita, Navita
id: 6ebe278d-ba0b-11ee-8184-f34cdc671de4
last_name: Navita
- first_name: Maria
full_name: Ibáñez, Maria
id: 43C61214-F248-11E8-B48F-1D18A9856A87
last_name: Ibáñez
orcid: 0000-0001-5013-2843
citation:
ama: Jakhar N, Ibáñez M. Electron highways are cooler. Science. 2024;383(6688):1184.
doi:10.1126/science.ado4077
apa: Jakhar, N., & Ibáñez, M. (2024). Electron highways are cooler. Science.
American Association for the Advancement of Science. https://doi.org/10.1126/science.ado4077
chicago: Jakhar, Navita, and Maria Ibáñez. “Electron Highways Are Cooler.” Science.
American Association for the Advancement of Science, 2024. https://doi.org/10.1126/science.ado4077.
ieee: N. Jakhar and M. Ibáñez, “Electron highways are cooler,” Science, vol.
383, no. 6688. American Association for the Advancement of Science, p. 1184, 2024.
ista: Jakhar N, Ibáñez M. 2024. Electron highways are cooler. Science. 383(6688),
1184.
mla: Jakhar, Navita, and Maria Ibáñez. “Electron Highways Are Cooler.” Science,
vol. 383, no. 6688, American Association for the Advancement of Science, 2024,
p. 1184, doi:10.1126/science.ado4077.
short: N. Jakhar, M. Ibáñez, Science 383 (2024) 1184.
date_created: 2024-03-24T23:00:58Z
date_published: 2024-03-14T00:00:00Z
date_updated: 2024-03-25T10:31:20Z
day: '14'
department:
- _id: MaIb
doi: 10.1126/science.ado4077
intvolume: ' 383'
issue: '6688'
language:
- iso: eng
month: '03'
oa_version: None
page: '1184'
project:
- _id: 9B8F7476-BA93-11EA-9121-9846C619BF3A
name: 'HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of
Semiconductors for Waste Heat Recovery'
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Electron highways are cooler
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 383
year: '2024'
...
---
_id: '13106'
abstract:
- lang: eng
text: Quantum entanglement is a key resource in currently developed quantum technologies.
Sharing this fragile property between superconducting microwave circuits and optical
or atomic systems would enable new functionalities, but this has been hindered
by an energy scale mismatch of >104 and the resulting mutually imposed loss and
noise. In this work, we created and verified entanglement between microwave and
optical fields in a millikelvin environment. Using an optically pulsed superconducting
electro-optical device, we show entanglement between propagating microwave and
optical fields in the continuous variable domain. This achievement not only paves
the way for entanglement between superconducting circuits and telecom wavelength
light, but also has wide-ranging implications for hybrid quantum networks in the
context of modularization, scaling, sensing, and cross-platform verification.
acknowledgement: This work was supported by the European Research Council (grant no.
758053, ERC StG QUNNECT) and the European Union’s Horizon 2020 Research and Innovation
Program (grant no. 899354, FETopen SuperQuLAN). L.Q. acknowledges generous support
from the ISTFELLOW program. W.H. is the recipient of an ISTplus postdoctoral fellowship
with funding from the European Union’s Horizon 2020 Research and Innovation Program
(Marie Sklodowska-Curie grant no. 754411). G.A. is the recipient of a DOC fellowship
of the Austrian Academy of Sciences at IST Austria. J.M.F. acknowledges support
from the Austrian Science Fund (FWF) through BeyondC (grant no. F7105) and the European
Union’s Horizon 2020 Research and Innovation Program (grant no. 862644, FETopen
QUARTET).
article_processing_charge: No
article_type: original
author:
- first_name: Rishabh
full_name: Sahu, Rishabh
id: 47D26E34-F248-11E8-B48F-1D18A9856A87
last_name: Sahu
orcid: 0000-0001-6264-2162
- first_name: Liu
full_name: Qiu, Liu
id: 45e99c0d-1eb1-11eb-9b96-ed8ab2983cac
last_name: Qiu
orcid: 0000-0003-4345-4267
- first_name: William J
full_name: Hease, William J
id: 29705398-F248-11E8-B48F-1D18A9856A87
last_name: Hease
- first_name: Georg M
full_name: Arnold, Georg M
id: 3770C838-F248-11E8-B48F-1D18A9856A87
last_name: Arnold
- first_name: Y.
full_name: Minoguchi, Y.
last_name: Minoguchi
- first_name: P.
full_name: Rabl, P.
last_name: Rabl
- first_name: Johannes M
full_name: Fink, Johannes M
id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
last_name: Fink
orcid: 0000-0001-8112-028X
citation:
ama: Sahu R, Qiu L, Hease WJ, et al. Entangling microwaves with light. Science.
2023;380(6646):718-721. doi:10.1126/science.adg3812
apa: Sahu, R., Qiu, L., Hease, W. J., Arnold, G. M., Minoguchi, Y., Rabl, P., &
Fink, J. M. (2023). Entangling microwaves with light. Science. American
Association for the Advancement of Science. https://doi.org/10.1126/science.adg3812
chicago: Sahu, Rishabh, Liu Qiu, William J Hease, Georg M Arnold, Y. Minoguchi,
P. Rabl, and Johannes M Fink. “Entangling Microwaves with Light.” Science.
American Association for the Advancement of Science, 2023. https://doi.org/10.1126/science.adg3812.
ieee: R. Sahu et al., “Entangling microwaves with light,” Science,
vol. 380, no. 6646. American Association for the Advancement of Science, pp. 718–721,
2023.
ista: Sahu R, Qiu L, Hease WJ, Arnold GM, Minoguchi Y, Rabl P, Fink JM. 2023. Entangling
microwaves with light. Science. 380(6646), 718–721.
mla: Sahu, Rishabh, et al. “Entangling Microwaves with Light.” Science, vol.
380, no. 6646, American Association for the Advancement of Science, 2023, pp.
718–21, doi:10.1126/science.adg3812.
short: R. Sahu, L. Qiu, W.J. Hease, G.M. Arnold, Y. Minoguchi, P. Rabl, J.M. Fink,
Science 380 (2023) 718–721.
date_created: 2023-05-31T11:39:24Z
date_published: 2023-05-18T00:00:00Z
date_updated: 2023-08-02T06:08:57Z
day: '18'
department:
- _id: JoFi
doi: 10.1126/science.adg3812
ec_funded: 1
external_id:
arxiv:
- '2301.03315'
isi:
- '000996515200004'
intvolume: ' 380'
isi: 1
issue: '6646'
keyword:
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2301.03315
month: '05'
oa: 1
oa_version: Preprint
page: 718-721
project:
- _id: 26336814-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '758053'
name: A Fiber Optic Transceiver for Superconducting Qubits
- _id: 9B868D20-BA93-11EA-9121-9846C619BF3A
call_identifier: H2020
grant_number: '899354'
name: Quantum Local Area Networks with Superconducting Qubits
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: 26927A52-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: F07105
name: Integrating superconducting quantum circuits
- _id: 237CBA6C-32DE-11EA-91FC-C7463DDC885E
call_identifier: H2020
grant_number: '862644'
name: Quantum readout techniques and technologies
- _id: 2671EB66-B435-11E9-9278-68D0E5697425
name: Coherent on-chip conversion of superconducting qubit signals from microwaves
to optical frequencies
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
related_material:
link:
- description: News on ISTA Website
relation: press_release
url: https://ista.ac.at/en/news/wiring-up-quantum-circuits-with-light/
record:
- id: '13122'
relation: research_data
status: public
status: public
title: Entangling microwaves with light
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 380
year: '2023'
...
---
_id: '14281'
abstract:
- lang: eng
text: In nature, proteins that switch between two conformations in response to environmental
stimuli structurally transduce biochemical information in a manner analogous to
how transistors control information flow in computing devices. Designing proteins
with two distinct but fully structured conformations is a challenge for protein
design as it requires sculpting an energy landscape with two distinct minima.
Here we describe the design of “hinge” proteins that populate one designed state
in the absence of ligand and a second designed state in the presence of ligand.
X-ray crystallography, electron microscopy, double electron-electron resonance
spectroscopy, and binding measurements demonstrate that despite the significant
structural differences the two states are designed with atomic level accuracy
and that the conformational and binding equilibria are closely coupled.
article_processing_charge: No
article_type: original
author:
- first_name: Florian M
full_name: Praetorius, Florian M
id: dfec9381-4341-11ee-8fd8-faa02bba7d62
last_name: Praetorius
- first_name: Philip J. Y.
full_name: Leung, Philip J. Y.
last_name: Leung
- first_name: Maxx H.
full_name: Tessmer, Maxx H.
last_name: Tessmer
- first_name: Adam
full_name: Broerman, Adam
last_name: Broerman
- first_name: Cullen
full_name: Demakis, Cullen
last_name: Demakis
- first_name: Acacia F.
full_name: Dishman, Acacia F.
last_name: Dishman
- first_name: Arvind
full_name: Pillai, Arvind
last_name: Pillai
- first_name: Abbas
full_name: Idris, Abbas
last_name: Idris
- first_name: David
full_name: Juergens, David
last_name: Juergens
- first_name: Justas
full_name: Dauparas, Justas
last_name: Dauparas
- first_name: Xinting
full_name: Li, Xinting
last_name: Li
- first_name: Paul M.
full_name: Levine, Paul M.
last_name: Levine
- first_name: Mila
full_name: Lamb, Mila
last_name: Lamb
- first_name: Ryanne K.
full_name: Ballard, Ryanne K.
last_name: Ballard
- first_name: Stacey R.
full_name: Gerben, Stacey R.
last_name: Gerben
- first_name: Hannah
full_name: Nguyen, Hannah
last_name: Nguyen
- first_name: Alex
full_name: Kang, Alex
last_name: Kang
- first_name: Banumathi
full_name: Sankaran, Banumathi
last_name: Sankaran
- first_name: Asim K.
full_name: Bera, Asim K.
last_name: Bera
- first_name: Brian F.
full_name: Volkman, Brian F.
last_name: Volkman
- first_name: Jeff
full_name: Nivala, Jeff
last_name: Nivala
- first_name: Stefan
full_name: Stoll, Stefan
last_name: Stoll
- first_name: David
full_name: Baker, David
last_name: Baker
citation:
ama: Praetorius FM, Leung PJY, Tessmer MH, et al. Design of stimulus-responsive
two-state hinge proteins. Science. 2023;381(6659):754-760. doi:10.1126/science.adg7731
apa: Praetorius, F. M., Leung, P. J. Y., Tessmer, M. H., Broerman, A., Demakis,
C., Dishman, A. F., … Baker, D. (2023). Design of stimulus-responsive two-state
hinge proteins. Science. American Association for the Advancement of Science.
https://doi.org/10.1126/science.adg7731
chicago: Praetorius, Florian M, Philip J. Y. Leung, Maxx H. Tessmer, Adam Broerman,
Cullen Demakis, Acacia F. Dishman, Arvind Pillai, et al. “Design of Stimulus-Responsive
Two-State Hinge Proteins.” Science. American Association for the Advancement
of Science, 2023. https://doi.org/10.1126/science.adg7731.
ieee: F. M. Praetorius et al., “Design of stimulus-responsive two-state hinge
proteins,” Science, vol. 381, no. 6659. American Association for the Advancement
of Science, pp. 754–760, 2023.
ista: Praetorius FM, Leung PJY, Tessmer MH, Broerman A, Demakis C, Dishman AF, Pillai
A, Idris A, Juergens D, Dauparas J, Li X, Levine PM, Lamb M, Ballard RK, Gerben
SR, Nguyen H, Kang A, Sankaran B, Bera AK, Volkman BF, Nivala J, Stoll S, Baker
D. 2023. Design of stimulus-responsive two-state hinge proteins. Science. 381(6659),
754–760.
mla: Praetorius, Florian M., et al. “Design of Stimulus-Responsive Two-State Hinge
Proteins.” Science, vol. 381, no. 6659, American Association for the Advancement
of Science, 2023, pp. 754–60, doi:10.1126/science.adg7731.
short: F.M. Praetorius, P.J.Y. Leung, M.H. Tessmer, A. Broerman, C. Demakis, A.F.
Dishman, A. Pillai, A. Idris, D. Juergens, J. Dauparas, X. Li, P.M. Levine, M.
Lamb, R.K. Ballard, S.R. Gerben, H. Nguyen, A. Kang, B. Sankaran, A.K. Bera, B.F.
Volkman, J. Nivala, S. Stoll, D. Baker, Science 381 (2023) 754–760.
date_created: 2023-09-06T12:04:23Z
date_published: 2023-08-17T00:00:00Z
date_updated: 2023-11-07T12:42:09Z
day: '17'
doi: 10.1126/science.adg7731
extern: '1'
external_id:
pmid:
- '37590357'
intvolume: ' 381'
issue: '6659'
language:
- iso: eng
month: '08'
oa_version: None
page: 754-760
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Design of stimulus-responsive two-state hinge proteins
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 381
year: '2023'
...
---
_id: '15085'
abstract:
- lang: eng
text: The hydrogen-rich outer layers of massive stars can be removed by interactions
with a binary companion. Theoretical models predict that this stripping produces
a population of hot helium stars of ~2 to 8 solar masses (M☉), however, only one
such system has been identified thus far. We used ultraviolet photometry to identify
potential stripped helium stars then investigated 25 of them using optical spectroscopy.
We identified stars with high temperatures (~60,000 to 100,000 kelvin), high surface
gravities, and hydrogen-depleted surfaces; 16 stars also showed binary motion.
These properties match expectations for stars with initial masses of 8 to 25 M☉
that were stripped by binary interaction. Their masses fall in the gap between
subdwarf helium stars and Wolf-Rayet stars. We propose that these stars could
be progenitors of stripped-envelope supernovae.
article_processing_charge: No
article_type: original
author:
- first_name: M. R.
full_name: Drout, M. R.
last_name: Drout
- first_name: Ylva Louise Linsdotter
full_name: Götberg, Ylva Louise Linsdotter
id: d0648d0c-0f64-11ee-a2e0-dd0faa2e4f7d
last_name: Götberg
orcid: 0000-0002-6960-6911
- first_name: B. A.
full_name: Ludwig, B. A.
last_name: Ludwig
- first_name: J. H.
full_name: Groh, J. H.
last_name: Groh
- first_name: S. E.
full_name: de Mink, S. E.
last_name: de Mink
- first_name: A. J. G.
full_name: O’Grady, A. J. G.
last_name: O’Grady
- first_name: N.
full_name: Smith, N.
last_name: Smith
citation:
ama: Drout MR, Götberg YLL, Ludwig BA, et al. An observed population of intermediate-mass
helium stars that have been stripped in binaries. Science. 2023;382(6676):1287-1291.
doi:10.1126/science.ade4970
apa: Drout, M. R., Götberg, Y. L. L., Ludwig, B. A., Groh, J. H., de Mink, S. E.,
O’Grady, A. J. G., & Smith, N. (2023). An observed population of intermediate-mass
helium stars that have been stripped in binaries. Science. American Association
for the Advancement of Science. https://doi.org/10.1126/science.ade4970
chicago: Drout, M. R., Ylva Louise Linsdotter Götberg, B. A. Ludwig, J. H. Groh,
S. E. de Mink, A. J. G. O’Grady, and N. Smith. “An Observed Population of Intermediate-Mass
Helium Stars That Have Been Stripped in Binaries.” Science. American Association
for the Advancement of Science, 2023. https://doi.org/10.1126/science.ade4970.
ieee: M. R. Drout et al., “An observed population of intermediate-mass helium
stars that have been stripped in binaries,” Science, vol. 382, no. 6676.
American Association for the Advancement of Science, pp. 1287–1291, 2023.
ista: Drout MR, Götberg YLL, Ludwig BA, Groh JH, de Mink SE, O’Grady AJG, Smith
N. 2023. An observed population of intermediate-mass helium stars that have been
stripped in binaries. Science. 382(6676), 1287–1291.
mla: Drout, M. R., et al. “An Observed Population of Intermediate-Mass Helium Stars
That Have Been Stripped in Binaries.” Science, vol. 382, no. 6676, American
Association for the Advancement of Science, 2023, pp. 1287–91, doi:10.1126/science.ade4970.
short: M.R. Drout, Y.L.L. Götberg, B.A. Ludwig, J.H. Groh, S.E. de Mink, A.J.G.
O’Grady, N. Smith, Science 382 (2023) 1287–1291.
date_created: 2024-03-05T09:40:28Z
date_published: 2023-12-14T00:00:00Z
date_updated: 2024-03-13T07:40:04Z
day: '14'
doi: 10.1126/science.ade4970
extern: '1'
external_id:
arxiv:
- '2307.00061'
pmid:
- '38096420'
intvolume: ' 382'
issue: '6676'
keyword:
- Stellar Astrophysics
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.2307.00061
month: '12'
oa: 1
oa_version: None
page: 1287-1291
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
related_material:
link:
- description: News on ISTA Website
relation: press_release
url: https://ista.ac.at/en/news/reaching-for-the-invisible-stars/
scopus_import: '1'
status: public
title: An observed population of intermediate-mass helium stars that have been stripped
in binaries
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 382
year: '2023'
...
---
_id: '11996'
abstract:
- lang: eng
text: If you mix fruit syrups with alcohol to make a schnapps, the two liquids will
remain perfectly blended forever. But if you mix oil with vinegar to make a vinaigrette,
the oil and vinegar will soon separate back into their previous selves. Such liquid-liquid
phase separation is a thermodynamically driven phenomenon and plays an important
role in many biological processes (1). Although energy injection at the macroscale
can reverse the phase separation—a strong shake is the normal response to a separated
vinaigrette—little is known about the effect of energy added at the microscopic
level on phase separation. This fundamental question has deep ramifications, notably
in biology, because active processes also make the interior of a living cell different
from a dead one. On page 768 of this issue, Adkins et al. (2) examine how mechanical
activity at the microscopic scale affects liquid-liquid phase separation and allows
liquids to climb surfaces.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Jérémie A
full_name: Palacci, Jérémie A
id: 8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d
last_name: Palacci
orcid: 0000-0002-7253-9465
citation:
ama: Palacci JA. A soft active matter that can climb walls. Science. 2022;377(6607):710-711.
doi:10.1126/science.adc9202
apa: Palacci, J. A. (2022). A soft active matter that can climb walls. Science.
American Association for the Advancement of Science. https://doi.org/10.1126/science.adc9202
chicago: Palacci, Jérémie A. “A Soft Active Matter That Can Climb Walls.” Science.
American Association for the Advancement of Science, 2022. https://doi.org/10.1126/science.adc9202.
ieee: J. A. Palacci, “A soft active matter that can climb walls,” Science,
vol. 377, no. 6607. American Association for the Advancement of Science, pp. 710–711,
2022.
ista: Palacci JA. 2022. A soft active matter that can climb walls. Science. 377(6607),
710–711.
mla: Palacci, Jérémie A. “A Soft Active Matter That Can Climb Walls.” Science,
vol. 377, no. 6607, American Association for the Advancement of Science, 2022,
pp. 710–11, doi:10.1126/science.adc9202.
short: J.A. Palacci, Science 377 (2022) 710–711.
date_created: 2022-08-28T22:02:00Z
date_published: 2022-08-12T00:00:00Z
date_updated: 2022-09-05T07:37:37Z
day: '12'
department:
- _id: JePa
doi: 10.1126/science.adc9202
external_id:
pmid:
- '35951689 '
intvolume: ' 377'
issue: '6607'
language:
- iso: eng
month: '08'
oa_version: None
page: 710-711
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: A soft active matter that can climb walls
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 377
year: '2022'
...
---
_id: '10713'
abstract:
- lang: eng
text: Cells migrate through crowded microenvironments within tissues during normal
development, immune response, and cancer metastasis. Although migration through
pores and tracks in the extracellular matrix (ECM) has been well studied, little
is known about cellular traversal into confining cell-dense tissues. We find that
embryonic tissue invasion by Drosophila macrophages requires division of an epithelial
ectodermal cell at the site of entry. Dividing ectodermal cells disassemble ECM
attachment formed by integrin-mediated focal adhesions next to mesodermal cells,
allowing macrophages to move their nuclei ahead and invade between two immediately
adjacent tissues. Invasion efficiency depends on division frequency, but reduction
of adhesion strength allows macrophage entry independently of division. This work
demonstrates that tissue dynamics can regulate cellular infiltration.
acknowledged_ssus:
- _id: Bio
acknowledgement: 'We thank J. Friml, C. Guet, T. Hurd, M. Fendrych and members of
the laboratory for comments on the manuscript; the Bioimaging Facility of IST Austria
for excellent support and T. Lecuit, E. Hafen, R. Levayer and A. Martin for fly
strains. This work was supported by a grant from the Austrian Science Fund FWF:
Lise Meitner Fellowship M2379-B28 to M.A and D.S., and internal funding from IST
Austria to D.S. and EMBL to S.D.R.'
article_processing_charge: No
article_type: original
author:
- first_name: Maria
full_name: Akhmanova, Maria
id: 3425EC26-F248-11E8-B48F-1D18A9856A87
last_name: Akhmanova
orcid: 0000-0003-1522-3162
- first_name: Shamsi
full_name: Emtenani, Shamsi
id: 49D32318-F248-11E8-B48F-1D18A9856A87
last_name: Emtenani
orcid: 0000-0001-6981-6938
- first_name: Daniel
full_name: Krueger, Daniel
last_name: Krueger
- first_name: Attila
full_name: György, Attila
id: 3BCEDBE0-F248-11E8-B48F-1D18A9856A87
last_name: György
orcid: 0000-0002-1819-198X
- first_name: Mariana
full_name: Pereira Guarda, Mariana
id: 6de81d9d-e2f2-11eb-945a-af8bc2a60b26
last_name: Pereira Guarda
- first_name: Mikhail
full_name: Vlasov, Mikhail
last_name: Vlasov
- first_name: Fedor
full_name: Vlasov, Fedor
last_name: Vlasov
- first_name: Andrei
full_name: Akopian, Andrei
last_name: Akopian
- first_name: Aparna
full_name: Ratheesh, Aparna
id: 2F064CFE-F248-11E8-B48F-1D18A9856A87
last_name: Ratheesh
- first_name: Stefano
full_name: De Renzis, Stefano
last_name: De Renzis
- first_name: Daria E
full_name: Siekhaus, Daria E
id: 3D224B9E-F248-11E8-B48F-1D18A9856A87
last_name: Siekhaus
orcid: 0000-0001-8323-8353
citation:
ama: Akhmanova M, Emtenani S, Krueger D, et al. Cell division in tissues enables
macrophage infiltration. Science. 2022;376(6591):394-396. doi:10.1126/science.abj0425
apa: Akhmanova, M., Emtenani, S., Krueger, D., György, A., Pereira Guarda, M., Vlasov,
M., … Siekhaus, D. E. (2022). Cell division in tissues enables macrophage infiltration.
Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.abj0425
chicago: Akhmanova, Maria, Shamsi Emtenani, Daniel Krueger, Attila György, Mariana
Pereira Guarda, Mikhail Vlasov, Fedor Vlasov, et al. “Cell Division in Tissues
Enables Macrophage Infiltration.” Science. American Association for the
Advancement of Science, 2022. https://doi.org/10.1126/science.abj0425.
ieee: M. Akhmanova et al., “Cell division in tissues enables macrophage infiltration,”
Science, vol. 376, no. 6591. American Association for the Advancement of
Science, pp. 394–396, 2022.
ista: Akhmanova M, Emtenani S, Krueger D, György A, Pereira Guarda M, Vlasov M,
Vlasov F, Akopian A, Ratheesh A, De Renzis S, Siekhaus DE. 2022. Cell division
in tissues enables macrophage infiltration. Science. 376(6591), 394–396.
mla: Akhmanova, Maria, et al. “Cell Division in Tissues Enables Macrophage Infiltration.”
Science, vol. 376, no. 6591, American Association for the Advancement of
Science, 2022, pp. 394–96, doi:10.1126/science.abj0425.
short: M. Akhmanova, S. Emtenani, D. Krueger, A. György, M. Pereira Guarda, M. Vlasov,
F. Vlasov, A. Akopian, A. Ratheesh, S. De Renzis, D.E. Siekhaus, Science 376 (2022)
394–396.
date_created: 2022-02-01T11:23:18Z
date_published: 2022-04-22T00:00:00Z
date_updated: 2023-08-02T14:06:15Z
day: '22'
department:
- _id: DaSi
doi: 10.1126/science.abj0425
external_id:
isi:
- '000788553700039'
pmid:
- '35446632'
intvolume: ' 376'
isi: 1
issue: '6591'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1101/2021.04.19.438995
month: '04'
oa: 1
oa_version: Preprint
page: 394-396
pmid: 1
project:
- _id: 264CBBAC-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: M02379
name: Modeling epithelial tissue mechanics during cell invasion
publication: Science
publication_identifier:
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
status: public
title: Cell division in tissues enables macrophage infiltration
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 376
year: '2022'
...
---
_id: '12116'
abstract:
- lang: eng
text: Russia’s unprovoked attack on Ukraine has destroyed civilian infrastructure,
including universities, research centers, and other academic infrastructure (1).
Many Ukrainian scholars and researchers remain in Ukraine, and their work has
suffered from major setbacks (2–4). We call on international scientists and institutions
to support them.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Karishma
full_name: Chhugani, Karishma
last_name: Chhugani
- first_name: Alina
full_name: Frolova, Alina
last_name: Frolova
- first_name: Yuriy
full_name: Salyha, Yuriy
last_name: Salyha
- first_name: Andrada
full_name: Fiscutean, Andrada
last_name: Fiscutean
- first_name: Oksana
full_name: Zlenko, Oksana
last_name: Zlenko
- first_name: Sanita
full_name: Reinsone, Sanita
last_name: Reinsone
- first_name: Walter W.
full_name: Wolfsberger, Walter W.
last_name: Wolfsberger
- first_name: Oleksandra V.
full_name: Ivashchenko, Oleksandra V.
last_name: Ivashchenko
- first_name: Megi
full_name: Maci, Megi
last_name: Maci
- first_name: Dmytro
full_name: Dziuba, Dmytro
last_name: Dziuba
- first_name: Andrii
full_name: Parkhomenko, Andrii
last_name: Parkhomenko
- first_name: Eric
full_name: Bortz, Eric
last_name: Bortz
- first_name: Fyodor
full_name: Kondrashov, Fyodor
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
- first_name: Paweł P.
full_name: Łabaj, Paweł P.
last_name: Łabaj
- first_name: Veronika
full_name: Romero, Veronika
last_name: Romero
- first_name: Jakub
full_name: Hlávka, Jakub
last_name: Hlávka
- first_name: Taras K.
full_name: Oleksyk, Taras K.
last_name: Oleksyk
- first_name: Serghei
full_name: Mangul, Serghei
last_name: Mangul
citation:
ama: Chhugani K, Frolova A, Salyha Y, et al. Remote opportunities for scholars in
Ukraine. Science. 2022;378(6626):1285-1286. doi:10.1126/science.adg0797
apa: Chhugani, K., Frolova, A., Salyha, Y., Fiscutean, A., Zlenko, O., Reinsone,
S., … Mangul, S. (2022). Remote opportunities for scholars in Ukraine. Science.
American Association for the Advancement of Science. https://doi.org/10.1126/science.adg0797
chicago: Chhugani, Karishma, Alina Frolova, Yuriy Salyha, Andrada Fiscutean, Oksana
Zlenko, Sanita Reinsone, Walter W. Wolfsberger, et al. “Remote Opportunities for
Scholars in Ukraine.” Science. American Association for the Advancement
of Science, 2022. https://doi.org/10.1126/science.adg0797.
ieee: K. Chhugani et al., “Remote opportunities for scholars in Ukraine,”
Science, vol. 378, no. 6626. American Association for the Advancement of
Science, pp. 1285–1286, 2022.
ista: Chhugani K, Frolova A, Salyha Y, Fiscutean A, Zlenko O, Reinsone S, Wolfsberger
WW, Ivashchenko OV, Maci M, Dziuba D, Parkhomenko A, Bortz E, Kondrashov F, Łabaj
PP, Romero V, Hlávka J, Oleksyk TK, Mangul S. 2022. Remote opportunities for scholars
in Ukraine. Science. 378(6626), 1285–1286.
mla: Chhugani, Karishma, et al. “Remote Opportunities for Scholars in Ukraine.”
Science, vol. 378, no. 6626, American Association for the Advancement of
Science, 2022, pp. 1285–86, doi:10.1126/science.adg0797.
short: K. Chhugani, A. Frolova, Y. Salyha, A. Fiscutean, O. Zlenko, S. Reinsone,
W.W. Wolfsberger, O.V. Ivashchenko, M. Maci, D. Dziuba, A. Parkhomenko, E. Bortz,
F. Kondrashov, P.P. Łabaj, V. Romero, J. Hlávka, T.K. Oleksyk, S. Mangul, Science
378 (2022) 1285–1286.
date_created: 2023-01-12T11:56:30Z
date_published: 2022-12-22T00:00:00Z
date_updated: 2023-10-03T11:01:06Z
day: '22'
department:
- _id: FyKo
doi: 10.1126/science.adg0797
external_id:
isi:
- '000963463700023'
intvolume: ' 378'
isi: 1
issue: '6626'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1126/science.adg0797
month: '12'
oa: 1
oa_version: Published Version
page: 1285-1286
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Remote opportunities for scholars in Ukraine
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 378
year: '2022'
...
---
_id: '14282'
abstract:
- lang: eng
text: Asymmetric multiprotein complexes that undergo subunit exchange play central
roles in biology but present a challenge for design because the components must
not only contain interfaces that enable reversible association but also be stable
and well behaved in isolation. We use implicit negative design to generate β sheet–mediated
heterodimers that can be assembled into a wide variety of complexes. The designs
are stable, folded, and soluble in isolation and rapidly assemble upon mixing,
and crystal structures are close to the computational models. We construct linearly
arranged hetero-oligomers with up to six different components, branched hetero-oligomers,
closed C4-symmetric two-component rings, and hetero-oligomers assembled on a cyclic
homo-oligomeric central hub and demonstrate that such complexes can readily reconfigure
through subunit exchange. Our approach provides a general route to designing asymmetric
reconfigurable protein systems.
article_number: abj7662
article_processing_charge: No
article_type: original
author:
- first_name: Danny D.
full_name: Sahtoe, Danny D.
last_name: Sahtoe
- first_name: Florian M
full_name: Praetorius, Florian M
id: dfec9381-4341-11ee-8fd8-faa02bba7d62
last_name: Praetorius
- first_name: Alexis
full_name: Courbet, Alexis
last_name: Courbet
- first_name: Yang
full_name: Hsia, Yang
last_name: Hsia
- first_name: Basile I. M.
full_name: Wicky, Basile I. M.
last_name: Wicky
- first_name: Natasha I.
full_name: Edman, Natasha I.
last_name: Edman
- first_name: Lauren M.
full_name: Miller, Lauren M.
last_name: Miller
- first_name: Bart J. R.
full_name: Timmermans, Bart J. R.
last_name: Timmermans
- first_name: Justin
full_name: Decarreau, Justin
last_name: Decarreau
- first_name: Hana M.
full_name: Morris, Hana M.
last_name: Morris
- first_name: Alex
full_name: Kang, Alex
last_name: Kang
- first_name: Asim K.
full_name: Bera, Asim K.
last_name: Bera
- first_name: David
full_name: Baker, David
last_name: Baker
citation:
ama: Sahtoe DD, Praetorius FM, Courbet A, et al. Reconfigurable asymmetric protein
assemblies through implicit negative design. Science. 2022;375(6578). doi:10.1126/science.abj7662
apa: Sahtoe, D. D., Praetorius, F. M., Courbet, A., Hsia, Y., Wicky, B. I. M., Edman,
N. I., … Baker, D. (2022). Reconfigurable asymmetric protein assemblies through
implicit negative design. Science. American Association for the Advancement
of Science. https://doi.org/10.1126/science.abj7662
chicago: Sahtoe, Danny D., Florian M Praetorius, Alexis Courbet, Yang Hsia, Basile
I. M. Wicky, Natasha I. Edman, Lauren M. Miller, et al. “Reconfigurable Asymmetric
Protein Assemblies through Implicit Negative Design.” Science. American
Association for the Advancement of Science, 2022. https://doi.org/10.1126/science.abj7662.
ieee: D. D. Sahtoe et al., “Reconfigurable asymmetric protein assemblies
through implicit negative design,” Science, vol. 375, no. 6578. American
Association for the Advancement of Science, 2022.
ista: Sahtoe DD, Praetorius FM, Courbet A, Hsia Y, Wicky BIM, Edman NI, Miller LM,
Timmermans BJR, Decarreau J, Morris HM, Kang A, Bera AK, Baker D. 2022. Reconfigurable
asymmetric protein assemblies through implicit negative design. Science. 375(6578),
abj7662.
mla: Sahtoe, Danny D., et al. “Reconfigurable Asymmetric Protein Assemblies through
Implicit Negative Design.” Science, vol. 375, no. 6578, abj7662, American
Association for the Advancement of Science, 2022, doi:10.1126/science.abj7662.
short: D.D. Sahtoe, F.M. Praetorius, A. Courbet, Y. Hsia, B.I.M. Wicky, N.I. Edman,
L.M. Miller, B.J.R. Timmermans, J. Decarreau, H.M. Morris, A. Kang, A.K. Bera,
D. Baker, Science 375 (2022).
date_created: 2023-09-06T12:05:42Z
date_published: 2022-01-21T00:00:00Z
date_updated: 2023-11-07T12:39:56Z
day: '21'
doi: 10.1126/science.abj7662
extern: '1'
external_id:
pmid:
- '35050655'
intvolume: ' 375'
issue: '6578'
language:
- iso: eng
month: '01'
oa_version: None
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Reconfigurable asymmetric protein assemblies through implicit negative design
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 375
year: '2022'
...
---
_id: '10616'
abstract:
- lang: eng
text: Electrons in moiré flat band systems can spontaneously break time-reversal
symmetry, giving rise to a quantized anomalous Hall effect. In this study, we
use a superconducting quantum interference device to image stray magnetic fields
in twisted bilayer graphene aligned to hexagonal boron nitride. We find a magnetization
of several Bohr magnetons per charge carrier, demonstrating that the magnetism
is primarily orbital in nature. Our measurements reveal a large change in the
magnetization as the chemical potential is swept across the quantum anomalous
Hall gap, consistent with the expected contribution of chiral edge states to the
magnetization of an orbital Chern insulator. Mapping the spatial evolution of
field-driven magnetic reversal, we find a series of reproducible micrometer-scale
domains pinned to structural disorder.
acknowledgement: 'We thank A. H. Macdonald, J. Zhu, M. Zaletel, and D. Xiao for discussions
of the results and E. Lachman for comments on the manuscript. Funding: The work
was primarily funded by the US Department of Energy under DE-SC0020043, with additional
support for instrumentation development supported by the Army Research Office under
grant W911NF-16-1-0361. K.W. and T.T. acknowledge support from the Elemental Strategy
Initiative conducted by MEXT, Japan, grant JPMXP0112101001; JSPS KAKENHI grant JP20H00354
and CREST grant JPMJCR15F3, JST. C.L.T. acknowledges support from the Hertz Foundation
and from the National Science Foundation Graduate Research Fellowship Program under
grant 1650114. This project is funded in part by the Gordon and Betty Moore Foundation’s
EPiQS Initiative, grant GBMF9471 to A.F.Y.'
article_processing_charge: No
article_type: original
author:
- first_name: C. L.
full_name: Tschirhart, C. L.
last_name: Tschirhart
- first_name: M.
full_name: Serlin, M.
last_name: Serlin
- first_name: Hryhoriy
full_name: Polshyn, Hryhoriy
id: edfc7cb1-526e-11ec-b05a-e6ecc27e4e48
last_name: Polshyn
orcid: 0000-0001-8223-8896
- first_name: A.
full_name: Shragai, A.
last_name: Shragai
- first_name: Z.
full_name: Xia, Z.
last_name: Xia
- first_name: J.
full_name: Zhu, J.
last_name: Zhu
- first_name: Y.
full_name: Zhang, Y.
last_name: Zhang
- first_name: K.
full_name: Watanabe, K.
last_name: Watanabe
- first_name: T.
full_name: Taniguchi, T.
last_name: Taniguchi
- first_name: M. E.
full_name: Huber, M. E.
last_name: Huber
- first_name: A. F.
full_name: Young, A. F.
last_name: Young
citation:
ama: Tschirhart CL, Serlin M, Polshyn H, et al. Imaging orbital ferromagnetism in
a moiré Chern insulator. Science. 2021;372(6548):1323-1327. doi:10.1126/science.abd3190
apa: Tschirhart, C. L., Serlin, M., Polshyn, H., Shragai, A., Xia, Z., Zhu, J.,
… Young, A. F. (2021). Imaging orbital ferromagnetism in a moiré Chern insulator.
Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.abd3190
chicago: Tschirhart, C. L., M. Serlin, Hryhoriy Polshyn, A. Shragai, Z. Xia, J.
Zhu, Y. Zhang, et al. “Imaging Orbital Ferromagnetism in a Moiré Chern Insulator.”
Science. American Association for the Advancement of Science, 2021. https://doi.org/10.1126/science.abd3190.
ieee: C. L. Tschirhart et al., “Imaging orbital ferromagnetism in a moiré
Chern insulator,” Science, vol. 372, no. 6548. American Association for
the Advancement of Science, pp. 1323–1327, 2021.
ista: Tschirhart CL, Serlin M, Polshyn H, Shragai A, Xia Z, Zhu J, Zhang Y, Watanabe
K, Taniguchi T, Huber ME, Young AF. 2021. Imaging orbital ferromagnetism in a
moiré Chern insulator. Science. 372(6548), 1323–1327.
mla: Tschirhart, C. L., et al. “Imaging Orbital Ferromagnetism in a Moiré Chern
Insulator.” Science, vol. 372, no. 6548, American Association for the Advancement
of Science, 2021, pp. 1323–27, doi:10.1126/science.abd3190.
short: C.L. Tschirhart, M. Serlin, H. Polshyn, A. Shragai, Z. Xia, J. Zhu, Y. Zhang,
K. Watanabe, T. Taniguchi, M.E. Huber, A.F. Young, Science 372 (2021) 1323–1327.
date_created: 2022-01-13T12:17:45Z
date_published: 2021-05-27T00:00:00Z
date_updated: 2022-01-13T14:11:36Z
day: '27'
doi: 10.1126/science.abd3190
extern: '1'
external_id:
arxiv:
- '2006.08053'
pmid:
- '34045322'
intvolume: ' 372'
issue: '6548'
keyword:
- multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2006.08053
month: '05'
oa: 1
oa_version: Preprint
page: 1323-1327
pmid: 1
publication: Science
publication_identifier:
eissn:
- 1095-9203
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Imaging orbital ferromagnetism in a moiré Chern insulator
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 372
year: '2021'
...
---
_id: '12187'
abstract:
- lang: eng
text: Genomes of germ cells present an existential vulnerability to organisms because
germ cell mutations will propagate to future generations. Transposable elements
are one source of such mutations. In the small flowering plant Arabidopsis, Long
et al. found that genome methylation in the male germline is directed by small
interfering RNAs (siRNAs) imperfectly transcribed from transposons (see the Perspective
by Mosher). These germline siRNAs silence germline transposons and establish inherited
methylation patterns in sperm, thus maintaining the integrity of the plant genome
across generations.
acknowledgement: 'We thank the John Innes Centre Bioimaging Facility (S. Lopez, E.
Wegel, and K. Findlay) for their assistance with microscopy and the Norwich BioScience
Institute Partnership Computing Infrastructure for Science Group for high-performance
computing resources. Funding: This work was funded by a European Research Council
Starting Grant (“SexMeth” 804981; J.L., J.W., and X.F.), a Sainsbury Charitable
Foundation studentship (J.W.), two Biotechnology and Biological Sciences Research
Council (BBSRC) grants (BBS0096201 and BBP0135111; W.S., M.V., and X.F.), two John
Innes Foundation studentships (B.A. and S.D.), and a BBSRC David Phillips Fellowship
(BBL0250431; H.G. and X.F.). Author contributions: J.L., J.W., and X.F. designed
the study and wrote the manuscript; J.L., W.S., B.A., H.G., and S.D. performed the
experiments; and J.L., J.W., B.A., H.G., S.D., M.V., and X.F. analyzed the data.
Competing interests: The authors declare no competing interests. Data and material
availability: All sequencing data have been deposited in the Gene Expression Omnibus
(GEO) under accession no. GSE161625. Accession nos. of published datasets used in
this study are listed in table S6. Published software used in this study include
Bowtie v1.2.2 (https://doi.org/10.1002/0471250953.bi1107s32), Bismark v0.22.2 (https://doi.org/10.1093/bioinformatics/btr167),
Kallisto v0.43.0 (https://doi.org/10.1038/nbt0816-888d), Shortstack v3.8.5 (https://doi.org/10.1534/g3.116.030452),
and Cutadapt v1.15 (https://doi.org/10.1089/cmb.2017.0096). TrimGalore v0.4.1 and
MarkDuplicates v1.141 are available from https://github.com/FelixKrueger/TrimGalore
and https://github.com/broadinstitute/picard, respectively. All remaining data are
in the main paper or the supplementary materials.'
article_processing_charge: No
article_type: original
author:
- first_name: Jincheng
full_name: Long, Jincheng
last_name: Long
- first_name: James
full_name: Walker, James
last_name: Walker
- first_name: Wenjing
full_name: She, Wenjing
last_name: She
- first_name: Billy
full_name: Aldridge, Billy
last_name: Aldridge
- first_name: Hongbo
full_name: Gao, Hongbo
last_name: Gao
- first_name: Samuel
full_name: Deans, Samuel
last_name: Deans
- first_name: Martin
full_name: Vickers, Martin
last_name: Vickers
- first_name: Xiaoqi
full_name: Feng, Xiaoqi
id: e0164712-22ee-11ed-b12a-d80fcdf35958
last_name: Feng
orcid: 0000-0002-4008-1234
citation:
ama: Long J, Walker J, She W, et al. Nurse cell--derived small RNAs define paternal
epigenetic inheritance in Arabidopsis. Science. 2021;373(6550). doi:10.1126/science.abh0556
apa: Long, J., Walker, J., She, W., Aldridge, B., Gao, H., Deans, S., … Feng, X.
(2021). Nurse cell--derived small RNAs define paternal epigenetic inheritance
in Arabidopsis. Science. American Association for the Advancement of Science
(AAAS). https://doi.org/10.1126/science.abh0556
chicago: Long, Jincheng, James Walker, Wenjing She, Billy Aldridge, Hongbo Gao,
Samuel Deans, Martin Vickers, and Xiaoqi Feng. “Nurse Cell--Derived Small RNAs
Define Paternal Epigenetic Inheritance in Arabidopsis.” Science. American
Association for the Advancement of Science (AAAS), 2021. https://doi.org/10.1126/science.abh0556.
ieee: J. Long et al., “Nurse cell--derived small RNAs define paternal epigenetic
inheritance in Arabidopsis,” Science, vol. 373, no. 6550. American Association
for the Advancement of Science (AAAS), 2021.
ista: Long J, Walker J, She W, Aldridge B, Gao H, Deans S, Vickers M, Feng X. 2021.
Nurse cell--derived small RNAs define paternal epigenetic inheritance in Arabidopsis.
Science. 373(6550).
mla: Long, Jincheng, et al. “Nurse Cell--Derived Small RNAs Define Paternal Epigenetic
Inheritance in Arabidopsis.” Science, vol. 373, no. 6550, American Association
for the Advancement of Science (AAAS), 2021, doi:10.1126/science.abh0556.
short: J. Long, J. Walker, W. She, B. Aldridge, H. Gao, S. Deans, M. Vickers, X.
Feng, Science 373 (2021).
date_created: 2023-01-16T09:15:14Z
date_published: 2021-07-02T00:00:00Z
date_updated: 2023-05-08T10:56:39Z
day: '02'
department:
- _id: XiFe
doi: 10.1126/science.abh0556
extern: '1'
external_id:
pmid:
- '34210850'
intvolume: ' 373'
issue: '6550'
keyword:
- Multidisciplinary
language:
- iso: eng
month: '07'
oa_version: None
pmid: 1
publication: Science
publication_identifier:
issn:
- 0036-8075
- 1095-9203
publication_status: published
publisher: American Association for the Advancement of Science (AAAS)
quality_controlled: '1'
scopus_import: '1'
status: public
title: Nurse cell--derived small RNAs define paternal epigenetic inheritance in Arabidopsis
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 373
year: '2021'
...