[{"author":[{"id":"3425EC26-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-1522-3162","first_name":"Maria","last_name":"Akhmanova","full_name":"Akhmanova, Maria"},{"full_name":"Emtenani, Shamsi","last_name":"Emtenani","first_name":"Shamsi","orcid":"0000-0001-6981-6938","id":"49D32318-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Krueger, Daniel","first_name":"Daniel","last_name":"Krueger"},{"full_name":"György, Attila","id":"3BCEDBE0-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-1819-198X","first_name":"Attila","last_name":"György"},{"full_name":"Pereira Guarda, Mariana","first_name":"Mariana","last_name":"Pereira Guarda","id":"6de81d9d-e2f2-11eb-945a-af8bc2a60b26"},{"last_name":"Vlasov","first_name":"Mikhail","full_name":"Vlasov, Mikhail"},{"first_name":"Fedor","last_name":"Vlasov","full_name":"Vlasov, Fedor"},{"full_name":"Akopian, Andrei","first_name":"Andrei","last_name":"Akopian"},{"last_name":"Ratheesh","first_name":"Aparna","id":"2F064CFE-F248-11E8-B48F-1D18A9856A87","full_name":"Ratheesh, Aparna"},{"last_name":"De Renzis","first_name":"Stefano","full_name":"De Renzis, Stefano"},{"full_name":"Siekhaus, Daria E","id":"3D224B9E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8323-8353","first_name":"Daria E","last_name":"Siekhaus"}],"volume":376,"date_created":"2022-02-01T11:23:18Z","date_updated":"2023-08-02T14:06:15Z","pmid":1,"year":"2022","acknowledgement":"We thank J. Friml, C. Guet, T. Hurd, M. Fendrych and members of the laboratory for comments on the manuscript; the Bioimaging Facility of IST Austria for excellent support and T. Lecuit, E. Hafen, R. Levayer and A. Martin for fly strains. This work was supported by a grant from the Austrian Science Fund FWF: Lise Meitner Fellowship M2379-B28 to M.A and D.S., and internal funding from IST Austria to D.S. and EMBL to S.D.R.","publisher":"American Association for the Advancement of Science","department":[{"_id":"DaSi"}],"publication_status":"published","publication_identifier":{"issn":["0036-8075"]},"month":"04","doi":"10.1126/science.abj0425","language":[{"iso":"eng"}],"acknowledged_ssus":[{"_id":"Bio"}],"tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png"},"oa":1,"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/2021.04.19.438995"}],"external_id":{"isi":["000788553700039"],"pmid":["35446632"]},"project":[{"grant_number":"M02379","_id":"264CBBAC-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","name":"Modeling epithelial tissue mechanics during cell invasion"}],"quality_controlled":"1","isi":1,"issue":"6591","abstract":[{"lang":"eng","text":"Cells migrate through crowded microenvironments within tissues during normal development, immune response, and cancer metastasis. Although migration through pores and tracks in the extracellular matrix (ECM) has been well studied, little is known about cellular traversal into confining cell-dense tissues. We find that embryonic tissue invasion by Drosophila macrophages requires division of an epithelial ectodermal cell at the site of entry. Dividing ectodermal cells disassemble ECM attachment formed by integrin-mediated focal adhesions next to mesodermal cells, allowing macrophages to move their nuclei ahead and invade between two immediately adjacent tissues. Invasion efficiency depends on division frequency, but reduction of adhesion strength allows macrophage entry independently of division. This work demonstrates that tissue dynamics can regulate cellular infiltration."}],"type":"journal_article","oa_version":"Preprint","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","_id":"10713","intvolume":" 376","status":"public","title":"Cell division in tissues enables macrophage infiltration","article_processing_charge":"No","day":"22","date_published":"2022-04-22T00:00:00Z","citation":{"apa":"Akhmanova, M., Emtenani, S., Krueger, D., György, A., Pereira Guarda, M., Vlasov, M., … Siekhaus, D. E. (2022). Cell division in tissues enables macrophage infiltration. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.abj0425","ieee":"M. Akhmanova et al., “Cell division in tissues enables macrophage infiltration,” Science, vol. 376, no. 6591. American Association for the Advancement of Science, pp. 394–396, 2022.","ista":"Akhmanova M, Emtenani S, Krueger D, György A, Pereira Guarda M, Vlasov M, Vlasov F, Akopian A, Ratheesh A, De Renzis S, Siekhaus DE. 2022. Cell division in tissues enables macrophage infiltration. Science. 376(6591), 394–396.","ama":"Akhmanova M, Emtenani S, Krueger D, et al. Cell division in tissues enables macrophage infiltration. Science. 2022;376(6591):394-396. doi:10.1126/science.abj0425","chicago":"Akhmanova, Maria, Shamsi Emtenani, Daniel Krueger, Attila György, Mariana Pereira Guarda, Mikhail Vlasov, Fedor Vlasov, et al. “Cell Division in Tissues Enables Macrophage Infiltration.” Science. American Association for the Advancement of Science, 2022. https://doi.org/10.1126/science.abj0425.","short":"M. Akhmanova, S. Emtenani, D. Krueger, A. György, M. Pereira Guarda, M. Vlasov, F. Vlasov, A. Akopian, A. Ratheesh, S. De Renzis, D.E. Siekhaus, Science 376 (2022) 394–396.","mla":"Akhmanova, Maria, et al. “Cell Division in Tissues Enables Macrophage Infiltration.” Science, vol. 376, no. 6591, American Association for the Advancement of Science, 2022, pp. 394–96, doi:10.1126/science.abj0425."},"publication":"Science","page":"394-396","article_type":"original"},{"publication_identifier":{"issn":["0036-8075"],"eissn":["1095-9203"]},"month":"12","doi":"10.1126/science.adg0797","language":[{"iso":"eng"}],"oa":1,"external_id":{"isi":["000963463700023"]},"main_file_link":[{"url":"https://doi.org/10.1126/science.adg0797","open_access":"1"}],"isi":1,"quality_controlled":"1","author":[{"first_name":"Karishma","last_name":"Chhugani","full_name":"Chhugani, Karishma"},{"first_name":"Alina","last_name":"Frolova","full_name":"Frolova, Alina"},{"first_name":"Yuriy","last_name":"Salyha","full_name":"Salyha, Yuriy"},{"full_name":"Fiscutean, Andrada","last_name":"Fiscutean","first_name":"Andrada"},{"first_name":"Oksana","last_name":"Zlenko","full_name":"Zlenko, Oksana"},{"full_name":"Reinsone, Sanita","first_name":"Sanita","last_name":"Reinsone"},{"full_name":"Wolfsberger, Walter W.","first_name":"Walter W.","last_name":"Wolfsberger"},{"first_name":"Oleksandra V.","last_name":"Ivashchenko","full_name":"Ivashchenko, Oleksandra V."},{"full_name":"Maci, Megi","last_name":"Maci","first_name":"Megi"},{"full_name":"Dziuba, Dmytro","first_name":"Dmytro","last_name":"Dziuba"},{"first_name":"Andrii","last_name":"Parkhomenko","full_name":"Parkhomenko, Andrii"},{"full_name":"Bortz, Eric","first_name":"Eric","last_name":"Bortz"},{"id":"44FDEF62-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8243-4694","first_name":"Fyodor","last_name":"Kondrashov","full_name":"Kondrashov, Fyodor"},{"full_name":"Łabaj, Paweł P.","last_name":"Łabaj","first_name":"Paweł P."},{"full_name":"Romero, Veronika","last_name":"Romero","first_name":"Veronika"},{"first_name":"Jakub","last_name":"Hlávka","full_name":"Hlávka, Jakub"},{"full_name":"Oleksyk, Taras K.","first_name":"Taras K.","last_name":"Oleksyk"},{"last_name":"Mangul","first_name":"Serghei","full_name":"Mangul, Serghei"}],"volume":378,"date_updated":"2023-10-03T11:01:06Z","date_created":"2023-01-12T11:56:30Z","year":"2022","department":[{"_id":"FyKo"}],"publisher":"American Association for the Advancement of Science","publication_status":"published","article_processing_charge":"No","day":"22","scopus_import":"1","date_published":"2022-12-22T00:00:00Z","citation":{"ama":"Chhugani K, Frolova A, Salyha Y, et al. Remote opportunities for scholars in Ukraine. Science. 2022;378(6626):1285-1286. doi:10.1126/science.adg0797","apa":"Chhugani, K., Frolova, A., Salyha, Y., Fiscutean, A., Zlenko, O., Reinsone, S., … Mangul, S. (2022). Remote opportunities for scholars in Ukraine. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.adg0797","ieee":"K. Chhugani et al., “Remote opportunities for scholars in Ukraine,” Science, vol. 378, no. 6626. American Association for the Advancement of Science, pp. 1285–1286, 2022.","ista":"Chhugani K, Frolova A, Salyha Y, Fiscutean A, Zlenko O, Reinsone S, Wolfsberger WW, Ivashchenko OV, Maci M, Dziuba D, Parkhomenko A, Bortz E, Kondrashov F, Łabaj PP, Romero V, Hlávka J, Oleksyk TK, Mangul S. 2022. Remote opportunities for scholars in Ukraine. Science. 378(6626), 1285–1286.","short":"K. Chhugani, A. Frolova, Y. Salyha, A. Fiscutean, O. Zlenko, S. Reinsone, W.W. Wolfsberger, O.V. Ivashchenko, M. Maci, D. Dziuba, A. Parkhomenko, E. Bortz, F. Kondrashov, P.P. Łabaj, V. Romero, J. Hlávka, T.K. Oleksyk, S. Mangul, Science 378 (2022) 1285–1286.","mla":"Chhugani, Karishma, et al. “Remote Opportunities for Scholars in Ukraine.” Science, vol. 378, no. 6626, American Association for the Advancement of Science, 2022, pp. 1285–86, doi:10.1126/science.adg0797.","chicago":"Chhugani, Karishma, Alina Frolova, Yuriy Salyha, Andrada Fiscutean, Oksana Zlenko, Sanita Reinsone, Walter W. Wolfsberger, et al. “Remote Opportunities for Scholars in Ukraine.” Science. American Association for the Advancement of Science, 2022. https://doi.org/10.1126/science.adg0797."},"publication":"Science","page":"1285-1286","article_type":"letter_note","issue":"6626","abstract":[{"lang":"eng","text":"Russia’s unprovoked attack on Ukraine has destroyed civilian infrastructure, including universities, research centers, and other academic infrastructure (1). Many Ukrainian scholars and researchers remain in Ukraine, and their work has suffered from major setbacks (2–4). We call on international scientists and institutions to support them."}],"type":"journal_article","oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"12116","intvolume":" 378","title":"Remote opportunities for scholars in Ukraine","status":"public"},{"doi":"10.1126/science.abj7662","language":[{"iso":"eng"}],"external_id":{"pmid":["35050655"]},"quality_controlled":"1","publication_identifier":{"eissn":["1095-9203"],"issn":["0036-8075"]},"month":"01","author":[{"last_name":"Sahtoe","first_name":"Danny D.","full_name":"Sahtoe, Danny D."},{"id":"dfec9381-4341-11ee-8fd8-faa02bba7d62","last_name":"Praetorius","first_name":"Florian M","full_name":"Praetorius, Florian M"},{"last_name":"Courbet","first_name":"Alexis","full_name":"Courbet, Alexis"},{"last_name":"Hsia","first_name":"Yang","full_name":"Hsia, Yang"},{"last_name":"Wicky","first_name":"Basile I. M.","full_name":"Wicky, Basile I. M."},{"first_name":"Natasha I.","last_name":"Edman","full_name":"Edman, Natasha I."},{"first_name":"Lauren M.","last_name":"Miller","full_name":"Miller, Lauren M."},{"full_name":"Timmermans, Bart J. R.","last_name":"Timmermans","first_name":"Bart J. R."},{"full_name":"Decarreau, Justin","last_name":"Decarreau","first_name":"Justin"},{"full_name":"Morris, Hana M.","first_name":"Hana M.","last_name":"Morris"},{"first_name":"Alex","last_name":"Kang","full_name":"Kang, Alex"},{"first_name":"Asim K.","last_name":"Bera","full_name":"Bera, Asim K."},{"full_name":"Baker, David","first_name":"David","last_name":"Baker"}],"volume":375,"date_created":"2023-09-06T12:05:42Z","date_updated":"2023-11-07T12:39:56Z","pmid":1,"year":"2022","publisher":"American Association for the Advancement of Science","publication_status":"published","extern":"1","article_number":"abj7662","date_published":"2022-01-21T00:00:00Z","citation":{"ama":"Sahtoe DD, Praetorius FM, Courbet A, et al. Reconfigurable asymmetric protein assemblies through implicit negative design. Science. 2022;375(6578). doi:10.1126/science.abj7662","apa":"Sahtoe, D. D., Praetorius, F. M., Courbet, A., Hsia, Y., Wicky, B. I. M., Edman, N. I., … Baker, D. (2022). Reconfigurable asymmetric protein assemblies through implicit negative design. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.abj7662","ieee":"D. D. Sahtoe et al., “Reconfigurable asymmetric protein assemblies through implicit negative design,” Science, vol. 375, no. 6578. American Association for the Advancement of Science, 2022.","ista":"Sahtoe DD, Praetorius FM, Courbet A, Hsia Y, Wicky BIM, Edman NI, Miller LM, Timmermans BJR, Decarreau J, Morris HM, Kang A, Bera AK, Baker D. 2022. Reconfigurable asymmetric protein assemblies through implicit negative design. Science. 375(6578), abj7662.","short":"D.D. Sahtoe, F.M. Praetorius, A. Courbet, Y. Hsia, B.I.M. Wicky, N.I. Edman, L.M. Miller, B.J.R. Timmermans, J. Decarreau, H.M. Morris, A. Kang, A.K. Bera, D. Baker, Science 375 (2022).","mla":"Sahtoe, Danny D., et al. “Reconfigurable Asymmetric Protein Assemblies through Implicit Negative Design.” Science, vol. 375, no. 6578, abj7662, American Association for the Advancement of Science, 2022, doi:10.1126/science.abj7662.","chicago":"Sahtoe, Danny D., Florian M Praetorius, Alexis Courbet, Yang Hsia, Basile I. M. Wicky, Natasha I. Edman, Lauren M. Miller, et al. “Reconfigurable Asymmetric Protein Assemblies through Implicit Negative Design.” Science. American Association for the Advancement of Science, 2022. https://doi.org/10.1126/science.abj7662."},"publication":"Science","article_type":"original","article_processing_charge":"No","day":"21","scopus_import":"1","oa_version":"None","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"14282","intvolume":" 375","title":"Reconfigurable asymmetric protein assemblies through implicit negative design","status":"public","issue":"6578","abstract":[{"text":"Asymmetric multiprotein complexes that undergo subunit exchange play central roles in biology but present a challenge for design because the components must not only contain interfaces that enable reversible association but also be stable and well behaved in isolation. We use implicit negative design to generate β sheet–mediated heterodimers that can be assembled into a wide variety of complexes. The designs are stable, folded, and soluble in isolation and rapidly assemble upon mixing, and crystal structures are close to the computational models. We construct linearly arranged hetero-oligomers with up to six different components, branched hetero-oligomers, closed C4-symmetric two-component rings, and hetero-oligomers assembled on a cyclic homo-oligomeric central hub and demonstrate that such complexes can readily reconfigure through subunit exchange. Our approach provides a general route to designing asymmetric reconfigurable protein systems.","lang":"eng"}],"type":"journal_article"},{"author":[{"last_name":"Tschirhart","first_name":"C. L.","full_name":"Tschirhart, C. L."},{"full_name":"Serlin, M.","last_name":"Serlin","first_name":"M."},{"full_name":"Polshyn, Hryhoriy","first_name":"Hryhoriy","last_name":"Polshyn","id":"edfc7cb1-526e-11ec-b05a-e6ecc27e4e48","orcid":"0000-0001-8223-8896"},{"last_name":"Shragai","first_name":"A.","full_name":"Shragai, A."},{"full_name":"Xia, Z.","last_name":"Xia","first_name":"Z."},{"first_name":"J.","last_name":"Zhu","full_name":"Zhu, J."},{"last_name":"Zhang","first_name":"Y.","full_name":"Zhang, Y."},{"full_name":"Watanabe, K.","first_name":"K.","last_name":"Watanabe"},{"full_name":"Taniguchi, T.","first_name":"T.","last_name":"Taniguchi"},{"first_name":"M. E.","last_name":"Huber","full_name":"Huber, M. E."},{"full_name":"Young, A. F.","last_name":"Young","first_name":"A. F."}],"volume":372,"date_updated":"2022-01-13T14:11:36Z","date_created":"2022-01-13T12:17:45Z","pmid":1,"acknowledgement":"We thank A. H. Macdonald, J. Zhu, M. Zaletel, and D. Xiao for discussions of the results and E. Lachman for comments on the manuscript. Funding: The work was primarily funded by the US Department of Energy under DE-SC0020043, with additional support for instrumentation development supported by the Army Research Office under grant W911NF-16-1-0361. K.W. and T.T. acknowledge support from the Elemental Strategy Initiative conducted by MEXT, Japan, grant JPMXP0112101001; JSPS KAKENHI grant JP20H00354 and CREST grant JPMJCR15F3, JST. C.L.T. acknowledges support from the Hertz Foundation and from the National Science Foundation Graduate Research Fellowship Program under grant 1650114. This project is funded in part by the Gordon and Betty Moore Foundation’s EPiQS Initiative, grant GBMF9471 to A.F.Y.","year":"2021","publisher":"American Association for the Advancement of Science","publication_status":"published","extern":"1","doi":"10.1126/science.abd3190","language":[{"iso":"eng"}],"external_id":{"arxiv":["2006.08053"],"pmid":["34045322"]},"main_file_link":[{"url":"https://arxiv.org/abs/2006.08053","open_access":"1"}],"oa":1,"quality_controlled":"1","publication_identifier":{"eissn":["1095-9203"],"issn":["0036-8075"]},"month":"05","oa_version":"Preprint","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","_id":"10616","intvolume":" 372","status":"public","title":"Imaging orbital ferromagnetism in a moiré Chern insulator","issue":"6548","abstract":[{"lang":"eng","text":"Electrons in moiré flat band systems can spontaneously break time-reversal symmetry, giving rise to a quantized anomalous Hall effect. In this study, we use a superconducting quantum interference device to image stray magnetic fields in twisted bilayer graphene aligned to hexagonal boron nitride. We find a magnetization of several Bohr magnetons per charge carrier, demonstrating that the magnetism is primarily orbital in nature. Our measurements reveal a large change in the magnetization as the chemical potential is swept across the quantum anomalous Hall gap, consistent with the expected contribution of chiral edge states to the magnetization of an orbital Chern insulator. Mapping the spatial evolution of field-driven magnetic reversal, we find a series of reproducible micrometer-scale domains pinned to structural disorder."}],"type":"journal_article","date_published":"2021-05-27T00:00:00Z","citation":{"ista":"Tschirhart CL, Serlin M, Polshyn H, Shragai A, Xia Z, Zhu J, Zhang Y, Watanabe K, Taniguchi T, Huber ME, Young AF. 2021. Imaging orbital ferromagnetism in a moiré Chern insulator. Science. 372(6548), 1323–1327.","ieee":"C. L. Tschirhart et al., “Imaging orbital ferromagnetism in a moiré Chern insulator,” Science, vol. 372, no. 6548. American Association for the Advancement of Science, pp. 1323–1327, 2021.","apa":"Tschirhart, C. L., Serlin, M., Polshyn, H., Shragai, A., Xia, Z., Zhu, J., … Young, A. F. (2021). Imaging orbital ferromagnetism in a moiré Chern insulator. Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.abd3190","ama":"Tschirhart CL, Serlin M, Polshyn H, et al. Imaging orbital ferromagnetism in a moiré Chern insulator. Science. 2021;372(6548):1323-1327. doi:10.1126/science.abd3190","chicago":"Tschirhart, C. L., M. Serlin, Hryhoriy Polshyn, A. Shragai, Z. Xia, J. Zhu, Y. Zhang, et al. “Imaging Orbital Ferromagnetism in a Moiré Chern Insulator.” Science. American Association for the Advancement of Science, 2021. https://doi.org/10.1126/science.abd3190.","mla":"Tschirhart, C. L., et al. “Imaging Orbital Ferromagnetism in a Moiré Chern Insulator.” Science, vol. 372, no. 6548, American Association for the Advancement of Science, 2021, pp. 1323–27, doi:10.1126/science.abd3190.","short":"C.L. Tschirhart, M. Serlin, H. Polshyn, A. Shragai, Z. Xia, J. Zhu, Y. Zhang, K. Watanabe, T. Taniguchi, M.E. Huber, A.F. Young, Science 372 (2021) 1323–1327."},"publication":"Science","page":"1323-1327","article_type":"original","article_processing_charge":"No","day":"27","scopus_import":"1","keyword":["multidisciplinary"]},{"scopus_import":"1","keyword":["Multidisciplinary"],"article_processing_charge":"No","day":"02","citation":{"ieee":"J. Long et al., “Nurse cell--derived small RNAs define paternal epigenetic inheritance in Arabidopsis,” Science, vol. 373, no. 6550. American Association for the Advancement of Science (AAAS), 2021.","apa":"Long, J., Walker, J., She, W., Aldridge, B., Gao, H., Deans, S., … Feng, X. (2021). Nurse cell--derived small RNAs define paternal epigenetic inheritance in Arabidopsis. Science. American Association for the Advancement of Science (AAAS). https://doi.org/10.1126/science.abh0556","ista":"Long J, Walker J, She W, Aldridge B, Gao H, Deans S, Vickers M, Feng X. 2021. Nurse cell--derived small RNAs define paternal epigenetic inheritance in Arabidopsis. Science. 373(6550).","ama":"Long J, Walker J, She W, et al. Nurse cell--derived small RNAs define paternal epigenetic inheritance in Arabidopsis. Science. 2021;373(6550). doi:10.1126/science.abh0556","chicago":"Long, Jincheng, James Walker, Wenjing She, Billy Aldridge, Hongbo Gao, Samuel Deans, Martin Vickers, and Xiaoqi Feng. “Nurse Cell--Derived Small RNAs Define Paternal Epigenetic Inheritance in Arabidopsis.” Science. American Association for the Advancement of Science (AAAS), 2021. https://doi.org/10.1126/science.abh0556.","short":"J. Long, J. Walker, W. She, B. Aldridge, H. Gao, S. Deans, M. Vickers, X. Feng, Science 373 (2021).","mla":"Long, Jincheng, et al. “Nurse Cell--Derived Small RNAs Define Paternal Epigenetic Inheritance in Arabidopsis.” Science, vol. 373, no. 6550, American Association for the Advancement of Science (AAAS), 2021, doi:10.1126/science.abh0556."},"publication":"Science","article_type":"original","date_published":"2021-07-02T00:00:00Z","type":"journal_article","issue":"6550","abstract":[{"lang":"eng","text":"Genomes of germ cells present an existential vulnerability to organisms because germ cell mutations will propagate to future generations. Transposable elements are one source of such mutations. In the small flowering plant Arabidopsis, Long et al. found that genome methylation in the male germline is directed by small interfering RNAs (siRNAs) imperfectly transcribed from transposons (see the Perspective by Mosher). These germline siRNAs silence germline transposons and establish inherited methylation patterns in sperm, thus maintaining the integrity of the plant genome across generations."}],"_id":"12187","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","intvolume":" 373","title":"Nurse cell--derived small RNAs define paternal epigenetic inheritance in Arabidopsis","status":"public","oa_version":"None","publication_identifier":{"issn":["0036-8075","1095-9203"]},"month":"07","external_id":{"pmid":["34210850"]},"quality_controlled":"1","doi":"10.1126/science.abh0556","language":[{"iso":"eng"}],"extern":"1","pmid":1,"acknowledgement":"We thank the John Innes Centre Bioimaging Facility (S. Lopez, E. Wegel, and K. Findlay) for their assistance with microscopy and the Norwich BioScience Institute Partnership Computing Infrastructure for Science Group for high-performance computing resources. Funding: This work was funded by a European Research Council Starting Grant (“SexMeth” 804981; J.L., J.W., and X.F.), a Sainsbury Charitable Foundation studentship (J.W.), two Biotechnology and Biological Sciences Research Council (BBSRC) grants (BBS0096201 and BBP0135111; W.S., M.V., and X.F.), two John Innes Foundation studentships (B.A. and S.D.), and a BBSRC David Phillips Fellowship (BBL0250431; H.G. and X.F.). Author contributions: J.L., J.W., and X.F. designed the study and wrote the manuscript; J.L., W.S., B.A., H.G., and S.D. performed the experiments; and J.L., J.W., B.A., H.G., S.D., M.V., and X.F. analyzed the data. Competing interests: The authors declare no competing interests. Data and material availability: All sequencing data have been deposited in the Gene Expression Omnibus (GEO) under accession no. GSE161625. Accession nos. of published datasets used in this study are listed in table S6. Published software used in this study include Bowtie v1.2.2 (https://doi.org/10.1002/0471250953.bi1107s32), Bismark v0.22.2 (https://doi.org/10.1093/bioinformatics/btr167), Kallisto v0.43.0 (https://doi.org/10.1038/nbt0816-888d), Shortstack v3.8.5 (https://doi.org/10.1534/g3.116.030452), and Cutadapt v1.15 (https://doi.org/10.1089/cmb.2017.0096). TrimGalore v0.4.1 and MarkDuplicates v1.141 are available from https://github.com/FelixKrueger/TrimGalore and https://github.com/broadinstitute/picard, respectively. All remaining data are in the main paper or the supplementary materials.","year":"2021","department":[{"_id":"XiFe"}],"publisher":"American Association for the Advancement of Science (AAAS)","publication_status":"published","author":[{"first_name":"Jincheng","last_name":"Long","full_name":"Long, Jincheng"},{"full_name":"Walker, James","first_name":"James","last_name":"Walker"},{"full_name":"She, Wenjing","last_name":"She","first_name":"Wenjing"},{"full_name":"Aldridge, Billy","first_name":"Billy","last_name":"Aldridge"},{"first_name":"Hongbo","last_name":"Gao","full_name":"Gao, Hongbo"},{"full_name":"Deans, Samuel","last_name":"Deans","first_name":"Samuel"},{"first_name":"Martin","last_name":"Vickers","full_name":"Vickers, Martin"},{"full_name":"Feng, Xiaoqi","last_name":"Feng","first_name":"Xiaoqi","orcid":"0000-0002-4008-1234","id":"e0164712-22ee-11ed-b12a-d80fcdf35958"}],"volume":373,"date_created":"2023-01-16T09:15:14Z","date_updated":"2023-05-08T10:56:39Z"}]