---
_id: '1820'
abstract:
- lang: eng
text: 'We consider partially observable Markov decision processes (POMDPs) with
a set of target states and every transition is associated with an integer cost.
The optimization objec- tive we study asks to minimize the expected total cost
till the target set is reached, while ensuring that the target set is reached
almost-surely (with probability 1). We show that for integer costs approximating
the optimal cost is undecidable. For positive costs, our results are as follows:
(i) we establish matching lower and upper bounds for the optimal cost and the
bound is double exponential; (ii) we show that the problem of approximating the
optimal cost is decidable and present ap- proximation algorithms developing on
the existing algorithms for POMDPs with finite-horizon objectives. While the worst-
case running time of our algorithm is double exponential, we present efficient
stopping criteria for the algorithm and show experimentally that it performs well
in many examples.'
acknowledgement: ' The research was partly supported by Austrian Science Fund (FWF)
Grant No P23499-N23, FWF NFN Grant No S11407-N23 (RiSE), ERC Start grant (279307:
Graph Games), and Microsoft faculty fellows award.'
alternative_title:
- Artifical Intelligence
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Martin
full_name: Chmelik, Martin
id: 3624234E-F248-11E8-B48F-1D18A9856A87
last_name: Chmelik
- first_name: Raghav
full_name: Gupta, Raghav
last_name: Gupta
- first_name: Ayush
full_name: Kanodia, Ayush
last_name: Kanodia
citation:
ama: 'Chatterjee K, Chmelik M, Gupta R, Kanodia A. Optimal cost almost-sure reachability
in POMDPs. In: Proceedings of the Twenty-Ninth AAAI Conference on Artificial
Intelligence . Vol 5. AAAI Press; 2015:3496-3502.'
apa: 'Chatterjee, K., Chmelik, M., Gupta, R., & Kanodia, A. (2015). Optimal
cost almost-sure reachability in POMDPs. In Proceedings of the Twenty-Ninth
AAAI Conference on Artificial Intelligence (Vol. 5, pp. 3496–3502). Austin,
TX, USA: AAAI Press.'
chicago: Chatterjee, Krishnendu, Martin Chmelik, Raghav Gupta, and Ayush Kanodia.
“Optimal Cost Almost-Sure Reachability in POMDPs.” In Proceedings of the Twenty-Ninth
AAAI Conference on Artificial Intelligence , 5:3496–3502. AAAI Press, 2015.
ieee: K. Chatterjee, M. Chmelik, R. Gupta, and A. Kanodia, “Optimal cost almost-sure
reachability in POMDPs,” in Proceedings of the Twenty-Ninth AAAI Conference
on Artificial Intelligence , Austin, TX, USA, 2015, vol. 5, pp. 3496–3502.
ista: 'Chatterjee K, Chmelik M, Gupta R, Kanodia A. 2015. Optimal cost almost-sure
reachability in POMDPs. Proceedings of the Twenty-Ninth AAAI Conference on Artificial
Intelligence . IAAI: Innovative Applications of Artificial Intelligence, Artifical
Intelligence, vol. 5, 3496–3502.'
mla: Chatterjee, Krishnendu, et al. “Optimal Cost Almost-Sure Reachability in POMDPs.”
Proceedings of the Twenty-Ninth AAAI Conference on Artificial Intelligence
, vol. 5, AAAI Press, 2015, pp. 3496–502.
short: K. Chatterjee, M. Chmelik, R. Gupta, A. Kanodia, in:, Proceedings of the
Twenty-Ninth AAAI Conference on Artificial Intelligence , AAAI Press, 2015, pp.
3496–3502.
conference:
end_date: 2015-01-30
location: Austin, TX, USA
name: 'IAAI: Innovative Applications of Artificial Intelligence'
start_date: 2015-01-25
date_created: 2018-12-11T11:54:11Z
date_published: 2015-06-01T00:00:00Z
date_updated: 2023-02-23T10:02:57Z
day: '01'
department:
- _id: KrCh
ec_funded: 1
external_id:
arxiv:
- '1411.3880'
intvolume: ' 5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1411.3880
month: '06'
oa: 1
oa_version: Preprint
page: 3496-3502
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
publication: 'Proceedings of the Twenty-Ninth AAAI Conference on Artificial Intelligence '
publication_status: published
publisher: AAAI Press
publist_id: '5286'
quality_controlled: '1'
related_material:
record:
- id: '1529'
relation: later_version
status: public
scopus_import: 1
status: public
title: Optimal cost almost-sure reachability in POMDPs
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2015'
...
---
_id: '1814'
abstract:
- lang: eng
text: 'We present an efficient wavefront tracking algorithm for animating bodies
of water that interact with their environment. Our contributions include: a novel
wavefront tracking technique that enables dispersion, refraction, reflection,
and diffraction in the same simulation; a unique multivalued function interpolation
method that enables our simulations to elegantly sidestep the Nyquist limit; a
dispersion approximation for efficiently amplifying the number of simulated waves
by several orders of magnitude; and additional extensions that allow for time-dependent
effects and interactive artistic editing of the resulting animation. Our contributions
combine to give us multitudes more wave details than similar algorithms, while
maintaining high frame rates and allowing close camera zooms.'
article_number: '27'
author:
- first_name: Stefan
full_name: Jeschke, Stefan
id: 44D6411A-F248-11E8-B48F-1D18A9856A87
last_name: Jeschke
- first_name: Christopher J
full_name: Wojtan, Christopher J
id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
last_name: Wojtan
orcid: 0000-0001-6646-5546
citation:
ama: Jeschke S, Wojtan C. Water wave animation via wavefront parameter interpolation.
ACM Transactions on Graphics. 2015;34(3). doi:10.1145/2714572
apa: Jeschke, S., & Wojtan, C. (2015). Water wave animation via wavefront parameter
interpolation. ACM Transactions on Graphics. ACM. https://doi.org/10.1145/2714572
chicago: Jeschke, Stefan, and Chris Wojtan. “Water Wave Animation via Wavefront
Parameter Interpolation.” ACM Transactions on Graphics. ACM, 2015. https://doi.org/10.1145/2714572.
ieee: S. Jeschke and C. Wojtan, “Water wave animation via wavefront parameter interpolation,”
ACM Transactions on Graphics, vol. 34, no. 3. ACM, 2015.
ista: Jeschke S, Wojtan C. 2015. Water wave animation via wavefront parameter interpolation.
ACM Transactions on Graphics. 34(3), 27.
mla: Jeschke, Stefan, and Chris Wojtan. “Water Wave Animation via Wavefront Parameter
Interpolation.” ACM Transactions on Graphics, vol. 34, no. 3, 27, ACM,
2015, doi:10.1145/2714572.
short: S. Jeschke, C. Wojtan, ACM Transactions on Graphics 34 (2015).
date_created: 2018-12-11T11:54:09Z
date_published: 2015-04-01T00:00:00Z
date_updated: 2023-02-23T10:15:40Z
day: '01'
ddc:
- '000'
department:
- _id: ChWo
doi: 10.1145/2714572
ec_funded: 1
file:
- access_level: open_access
checksum: 67c9f4fa370def68cdf31299e48bc91f
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:12:15Z
date_updated: 2020-07-14T12:45:17Z
file_id: '4933'
file_name: IST-2016-575-v1+1_wavefront_preprint.pdf
file_size: 23712153
relation: main_file
file_date_updated: 2020-07-14T12:45:17Z
has_accepted_license: '1'
intvolume: ' 34'
issue: '3'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Submitted Version
project:
- _id: 25357BD2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 24352-N23
name: 'Deep Pictures: Creating Visual and Haptic Vector Images'
- _id: 2533E772-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '638176'
name: Efficient Simulation of Natural Phenomena at Extremely Large Scales
publication: ACM Transactions on Graphics
publication_status: published
publisher: ACM
publist_id: '5292'
pubrep_id: '575'
quality_controlled: '1'
scopus_import: 1
status: public
title: Water wave animation via wavefront parameter interpolation
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2015'
...
---
_id: '1818'
abstract:
- lang: eng
text: 'Why do species not adapt to ever-wider ranges of conditions, gradually expanding
their ecological niche and geographic range? Gene flow across environments has
two conflicting effects: although it increases genetic variation, which is a prerequisite
for adaptation, gene flow may swamp adaptation to local conditions. In 1956, Haldane
proposed that, when the environment varies across space, "swamping"
by gene flow creates a positive feedback between low population size and maladaptation,
leading to a sharp range margin. However, current deterministic theory shows that,
when variance can evolve, there is no such limit. Using simple analytical tools
and simulations, we show that genetic drift can generate a sharp margin to a species''
range, by reducing genetic variance below the level needed for adaptation to spatially
variable conditions. Aided by separation of ecological and evolutionary timescales,
the identified effective dimensionless parameters reveal a simple threshold that
predicts when adaptation at the range margin fails. Two observable parameters
determine the threshold: (i) the effective environmental gradient, which can be
measured by the loss of fitness due to dispersal to a different environment; and
(ii) the efficacy of selection relative to genetic drift. The theory predicts
sharp range margins even in the absence of abrupt changes in the environment.
Furthermore, it implies that gradual worsening of conditions across a species''
habitat may lead to a sudden range fragmentation, when adaptation to a wide span
of conditions within a single species becomes impossible.'
author:
- first_name: Jitka
full_name: Polechova, Jitka
id: 3BBFB084-F248-11E8-B48F-1D18A9856A87
last_name: Polechova
orcid: 0000-0003-0951-3112
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Polechova J, Barton NH. Limits to adaptation along environmental gradients.
PNAS. 2015;112(20):6401-6406. doi:10.1073/pnas.1421515112
apa: Polechova, J., & Barton, N. H. (2015). Limits to adaptation along environmental
gradients. PNAS. National Academy of Sciences. https://doi.org/10.1073/pnas.1421515112
chicago: Polechova, Jitka, and Nicholas H Barton. “Limits to Adaptation along Environmental
Gradients.” PNAS. National Academy of Sciences, 2015. https://doi.org/10.1073/pnas.1421515112.
ieee: J. Polechova and N. H. Barton, “Limits to adaptation along environmental gradients,”
PNAS, vol. 112, no. 20. National Academy of Sciences, pp. 6401–6406, 2015.
ista: Polechova J, Barton NH. 2015. Limits to adaptation along environmental gradients.
PNAS. 112(20), 6401–6406.
mla: Polechova, Jitka, and Nicholas H. Barton. “Limits to Adaptation along Environmental
Gradients.” PNAS, vol. 112, no. 20, National Academy of Sciences, 2015,
pp. 6401–06, doi:10.1073/pnas.1421515112.
short: J. Polechova, N.H. Barton, PNAS 112 (2015) 6401–6406.
date_created: 2018-12-11T11:54:11Z
date_published: 2015-05-19T00:00:00Z
date_updated: 2021-01-12T06:53:24Z
day: '19'
department:
- _id: NiBa
doi: 10.1073/pnas.1421515112
ec_funded: 1
external_id:
pmid:
- '25941385'
intvolume: ' 112'
issue: '20'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443383/
month: '05'
oa: 1
oa_version: Submitted Version
page: 6401 - 6406
pmid: 1
project:
- _id: 25B07788-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '250152'
name: Limits to selection in biology and in evolutionary computation
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '5288'
quality_controlled: '1'
scopus_import: 1
status: public
title: Limits to adaptation along environmental gradients
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 112
year: '2015'
...
---
_id: '1819'
abstract:
- lang: eng
text: 'The sessile life style of plants creates the need to deal with an often adverse
environment, in which water availability can change on a daily basis, challenging
the cellular physiology and integrity. Changes in osmotic conditions disrupt the
equilibrium of the plasma membrane: hypoosmotic conditions increase and hyperosmotic
environment decrease the cell volume. Here, we show that short-term extracellular
osmotic treatments are closely followed by a shift in the balance between endocytosis
and exocytosis in root meristem cells. Acute hyperosmotic treatments (ionic and
nonionic) enhance clathrin-mediated endocytosis simultaneously attenuating exocytosis,
whereas hypoosmotic treatments have the opposite effects. In addition to clathrin
recruitment to the plasma membrane, components of early endocytic trafficking
are essential during hyperosmotic stress responses. Consequently, growth of seedlings
defective in elements of clathrin or early endocytic machinery is more sensitive
to hyperosmotic treatments. We also found that the endocytotic response to a change
of osmotic status in the environment is dominant over the presumably evolutionary
more recent regulatory effect of plant hormones, such as auxin. These results
imply that osmotic perturbation influences the balance between endocytosis and
exocytosis acting through clathrin-mediated endocytosis. We propose that tension
on the plasma membrane determines the addition or removal of membranes at the
cell surface, thus preserving cell integrity.'
acknowledgement: This work was supported by the European Research Council (project
ERC-2011-StG-20101109-PSDP); European Social Fund (CZ.1.07/2.3.00/20.0043) and the
Czech Science Foundation GAČR (GA13-40637S) to J.F.; project Postdoc I. (CZ.1.07/2.3.00/30.0009)
co-financed by the European Social Fund and the state budget of the Czech Republic
to M.Z. and T.N..
author:
- first_name: Marta
full_name: Zwiewka, Marta
last_name: Zwiewka
- first_name: Tomasz
full_name: Nodzyński, Tomasz
last_name: Nodzyński
- first_name: Stéphanie
full_name: Robert, Stéphanie
last_name: Robert
- first_name: Steffen
full_name: Vanneste, Steffen
last_name: Vanneste
- first_name: Jiřĺ
full_name: Friml, Jiřĺ
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Zwiewka M, Nodzyński T, Robert S, Vanneste S, Friml J. Osmotic stress modulates
the balance between exocytosis and clathrin mediated endocytosis in Arabidopsis
thaliana. Molecular Plant. 2015;8(8):1175-1187. doi:10.1016/j.molp.2015.03.007
apa: Zwiewka, M., Nodzyński, T., Robert, S., Vanneste, S., & Friml, J. (2015).
Osmotic stress modulates the balance between exocytosis and clathrin mediated
endocytosis in Arabidopsis thaliana. Molecular Plant. Elsevier. https://doi.org/10.1016/j.molp.2015.03.007
chicago: Zwiewka, Marta, Tomasz Nodzyński, Stéphanie Robert, Steffen Vanneste, and
Jiří Friml. “Osmotic Stress Modulates the Balance between Exocytosis and Clathrin
Mediated Endocytosis in Arabidopsis Thaliana.” Molecular Plant. Elsevier,
2015. https://doi.org/10.1016/j.molp.2015.03.007.
ieee: M. Zwiewka, T. Nodzyński, S. Robert, S. Vanneste, and J. Friml, “Osmotic stress
modulates the balance between exocytosis and clathrin mediated endocytosis in
Arabidopsis thaliana,” Molecular Plant, vol. 8, no. 8. Elsevier, pp. 1175–1187,
2015.
ista: Zwiewka M, Nodzyński T, Robert S, Vanneste S, Friml J. 2015. Osmotic stress
modulates the balance between exocytosis and clathrin mediated endocytosis in
Arabidopsis thaliana. Molecular Plant. 8(8), 1175–1187.
mla: Zwiewka, Marta, et al. “Osmotic Stress Modulates the Balance between Exocytosis
and Clathrin Mediated Endocytosis in Arabidopsis Thaliana.” Molecular Plant,
vol. 8, no. 8, Elsevier, 2015, pp. 1175–87, doi:10.1016/j.molp.2015.03.007.
short: M. Zwiewka, T. Nodzyński, S. Robert, S. Vanneste, J. Friml, Molecular Plant
8 (2015) 1175–1187.
date_created: 2018-12-11T11:54:11Z
date_published: 2015-08-03T00:00:00Z
date_updated: 2021-01-12T06:53:24Z
day: '03'
department:
- _id: JiFr
doi: 10.1016/j.molp.2015.03.007
ec_funded: 1
intvolume: ' 8'
issue: '8'
language:
- iso: eng
month: '08'
oa_version: None
page: 1175 - 1187
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '282300'
name: Polarity and subcellular dynamics in plants
publication: Molecular Plant
publication_status: published
publisher: Elsevier
publist_id: '5287'
quality_controlled: '1'
scopus_import: 1
status: public
title: Osmotic stress modulates the balance between exocytosis and clathrin mediated
endocytosis in Arabidopsis thaliana
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2015'
...
---
_id: '1823'
abstract:
- lang: eng
text: Abstract Drug combinations are increasingly important in disease treatments,
for combating drug resistance, and for elucidating fundamental relationships in
cell physiology. When drugs are combined, their individual effects on cells may
be amplified or weakened. Such drug interactions are crucial for treatment efficacy,
but their underlying mechanisms remain largely unknown. To uncover the causes
of drug interactions, we developed a systematic approach based on precise quantification
of the individual and joint effects of antibiotics on growth of genome-wide Escherichia
coli gene deletion strains. We found that drug interactions between antibiotics
representing the main modes of action are highly robust to genetic perturbation.
This robustness is encapsulated in a general principle of bacterial growth, which
enables the quantitative prediction of mutant growth rates under drug combinations.
Rare violations of this principle exposed recurring cellular functions controlling
drug interactions. In particular, we found that polysaccharide and ATP synthesis
control multiple drug interactions with previously unexplained mechanisms, and
small molecule adjuvants targeting these functions synthetically reshape drug
interactions in predictable ways. These results provide a new conceptual framework
for the design of multidrug combinations and suggest that there are universal
mechanisms at the heart of most drug interactions. Synopsis A general principle
of bacterial growth enables the prediction of mutant growth rates under drug combinations.
Rare violations of this principle expose cellular functions that control drug
interactions and can be targeted by small molecules to alter drug interactions
in predictable ways. Drug interactions between antibiotics are highly robust to
genetic perturbations. A general principle of bacterial growth enables the prediction
of mutant growth rates under drug combinations. Rare violations of this principle
expose cellular functions that control drug interactions. Diverse drug interactions
are controlled by recurring cellular functions, including LPS synthesis and ATP
synthesis. A general principle of bacterial growth enables the prediction of mutant
growth rates under drug combinations. Rare violations of this principle expose
cellular functions that control drug interactions and can be targeted by small
molecules to alter drug interactions in predictable ways.
article_number: '807'
author:
- first_name: Guillaume
full_name: Chevereau, Guillaume
id: 424D78A0-F248-11E8-B48F-1D18A9856A87
last_name: Chevereau
- first_name: Mark Tobias
full_name: Bollenbach, Mark Tobias
id: 3E6DB97A-F248-11E8-B48F-1D18A9856A87
last_name: Bollenbach
orcid: 0000-0003-4398-476X
citation:
ama: Chevereau G, Bollenbach MT. Systematic discovery of drug interaction mechanisms.
Molecular Systems Biology. 2015;11(4). doi:10.15252/msb.20156098
apa: Chevereau, G., & Bollenbach, M. T. (2015). Systematic discovery of drug
interaction mechanisms. Molecular Systems Biology. Nature Publishing Group.
https://doi.org/10.15252/msb.20156098
chicago: Chevereau, Guillaume, and Mark Tobias Bollenbach. “Systematic Discovery
of Drug Interaction Mechanisms.” Molecular Systems Biology. Nature Publishing
Group, 2015. https://doi.org/10.15252/msb.20156098.
ieee: G. Chevereau and M. T. Bollenbach, “Systematic discovery of drug interaction
mechanisms,” Molecular Systems Biology, vol. 11, no. 4. Nature Publishing
Group, 2015.
ista: Chevereau G, Bollenbach MT. 2015. Systematic discovery of drug interaction
mechanisms. Molecular Systems Biology. 11(4), 807.
mla: Chevereau, Guillaume, and Mark Tobias Bollenbach. “Systematic Discovery of
Drug Interaction Mechanisms.” Molecular Systems Biology, vol. 11, no. 4,
807, Nature Publishing Group, 2015, doi:10.15252/msb.20156098.
short: G. Chevereau, M.T. Bollenbach, Molecular Systems Biology 11 (2015).
date_created: 2018-12-11T11:54:12Z
date_published: 2015-04-01T00:00:00Z
date_updated: 2021-01-12T06:53:26Z
day: '01'
ddc:
- '570'
department:
- _id: ToBo
doi: 10.15252/msb.20156098
ec_funded: 1
file:
- access_level: open_access
checksum: 4289b518fbe2166682fb1a1ef9b405f3
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:14:34Z
date_updated: 2020-07-14T12:45:17Z
file_id: '5087'
file_name: IST-2015-395-v1+1_807.full.pdf
file_size: 1273573
relation: main_file
file_date_updated: 2020-07-14T12:45:17Z
has_accepted_license: '1'
intvolume: ' 11'
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: 25E9AF9E-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P27201-B22
name: Revealing the mechanisms underlying drug interactions
- _id: 25EB3A80-B435-11E9-9278-68D0E5697425
grant_number: RGP0042/2013
name: Revealing the fundamental limits of cell growth
- _id: 25E83C2C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '303507'
name: Optimality principles in responses to antibiotics
publication: Molecular Systems Biology
publication_status: published
publisher: Nature Publishing Group
publist_id: '5283'
pubrep_id: '395'
quality_controlled: '1'
scopus_import: 1
status: public
title: Systematic discovery of drug interaction mechanisms
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2015'
...
---
_id: '1824'
abstract:
- lang: eng
text: Condensation phenomena arise through a collective behaviour of particles.
They are observed in both classical and quantum systems, ranging from the formation
of traffic jams in mass transport models to the macroscopic occupation of the
energetic ground state in ultra-cold bosonic gases (Bose-Einstein condensation).
Recently, it has been shown that a driven and dissipative system of bosons may
form multiple condensates. Which states become the condensates has, however, remained
elusive thus far. The dynamics of this condensation are described by coupled birth-death
processes, which also occur in evolutionary game theory. Here we apply concepts
from evolutionary game theory to explain the formation of multiple condensates
in such driven-dissipative bosonic systems. We show that the vanishing of relative
entropy production determines their selection. The condensation proceeds exponentially
fast, but the system never comes to rest. Instead, the occupation numbers of condensates
may oscillate, as we demonstrate for a rock-paper-scissors game of condensates.
article_number: '6977'
author:
- first_name: Johannes
full_name: Knebel, Johannes
last_name: Knebel
- first_name: Markus
full_name: Weber, Markus
last_name: Weber
- first_name: Torben H
full_name: Krüger, Torben H
id: 3020C786-F248-11E8-B48F-1D18A9856A87
last_name: Krüger
orcid: 0000-0002-4821-3297
- first_name: Erwin
full_name: Frey, Erwin
last_name: Frey
citation:
ama: Knebel J, Weber M, Krüger TH, Frey E. Evolutionary games of condensates in
coupled birth-death processes. Nature Communications. 2015;6. doi:10.1038/ncomms7977
apa: Knebel, J., Weber, M., Krüger, T. H., & Frey, E. (2015). Evolutionary games
of condensates in coupled birth-death processes. Nature Communications.
Nature Publishing Group. https://doi.org/10.1038/ncomms7977
chicago: Knebel, Johannes, Markus Weber, Torben H Krüger, and Erwin Frey. “Evolutionary
Games of Condensates in Coupled Birth-Death Processes.” Nature Communications.
Nature Publishing Group, 2015. https://doi.org/10.1038/ncomms7977.
ieee: J. Knebel, M. Weber, T. H. Krüger, and E. Frey, “Evolutionary games of condensates
in coupled birth-death processes,” Nature Communications, vol. 6. Nature
Publishing Group, 2015.
ista: Knebel J, Weber M, Krüger TH, Frey E. 2015. Evolutionary games of condensates
in coupled birth-death processes. Nature Communications. 6, 6977.
mla: Knebel, Johannes, et al. “Evolutionary Games of Condensates in Coupled Birth-Death
Processes.” Nature Communications, vol. 6, 6977, Nature Publishing Group,
2015, doi:10.1038/ncomms7977.
short: J. Knebel, M. Weber, T.H. Krüger, E. Frey, Nature Communications 6 (2015).
date_created: 2018-12-11T11:54:13Z
date_published: 2015-04-24T00:00:00Z
date_updated: 2021-01-12T06:53:26Z
day: '24'
ddc:
- '530'
department:
- _id: LaEr
doi: 10.1038/ncomms7977
file:
- access_level: open_access
checksum: c4cffb5c8b245e658a34eac71a03e7cc
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:16:54Z
date_updated: 2020-07-14T12:45:17Z
file_id: '5245'
file_name: IST-2016-451-v1+1_ncomms7977.pdf
file_size: 1151501
relation: main_file
file_date_updated: 2020-07-14T12:45:17Z
has_accepted_license: '1'
intvolume: ' 6'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_status: published
publisher: Nature Publishing Group
publist_id: '5282'
pubrep_id: '451'
quality_controlled: '1'
scopus_import: 1
status: public
title: Evolutionary games of condensates in coupled birth-death processes
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2015'
...
---
_id: '1831'
abstract:
- lang: eng
text: This paper introduces a theme issue presenting the latest developments in
research on the impacts of sociality on health and fitness. The articles that
follow cover research on societies ranging from insects to humans. Variation in
measures of fitness (i.e. survival and reproduction) has been linked to various
aspects of sociality in humans and animals alike, and variability in individual
health and condition has been recognized as a key mediator of these relationships.
Viewed from a broad evolutionary perspective, the evolutionary transitions from
a solitary lifestyle to group living have resulted in several new health-related
costs and benefits of sociality. Social transmission of parasites within groups
represents a major cost of group living, but some behavioural mechanisms, such
as grooming, have evolved repeatedly to reduce this cost. Group living also has
created novel costs in terms of altered susceptibility to infectious and non-infectious
disease as a result of the unavoidable physiological consequences of social competition
and integration, which are partly alleviated by social buffering in some vertebrates.
Here, we define the relevant aspects of sociality, summarize their health-related
costs and benefits, and discuss possible fitness measures in different study systems.
Given the pervasive effects of social factors on health and fitness, we propose
a synthesis of existing conceptual approaches in disease ecology, ecological immunology
and behavioural neurosciences by adding sociality as a key factor, with the goal
to generate a broader framework for organismal integration of health-related research.
acknowledgement: We thank the German Research Foundation (DFG), the Ministry of Science
and Culture of Lower-Saxony (MWK Hannover) and the German Primate Centre (DPZ) for
their support of the 9. Göttinger Freilandtage in 2013, a conference at which most
contributions to this issue were first presented, the referees of the contributions
to this issue for their constructive comments, Meggan Craft for comments, and Helen
Eaton for her support in producing this theme issue.
article_number: '20140116'
author:
- first_name: Peter
full_name: Kappeler, Peter
last_name: Kappeler
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
- first_name: Charles
full_name: Nunn, Charles
last_name: Nunn
citation:
ama: 'Kappeler P, Cremer S, Nunn C. Sociality and health: Impacts of sociality on
disease susceptibility and transmission in animal and human societies. Philosophical
Transactions of the Royal Society of London Series B, Biological Sciences.
2015;370(1669). doi:10.1098/rstb.2014.0116'
apa: 'Kappeler, P., Cremer, S., & Nunn, C. (2015). Sociality and health: Impacts
of sociality on disease susceptibility and transmission in animal and human societies.
Philosophical Transactions of the Royal Society of London. Series B, Biological
Sciences. Royal Society. https://doi.org/10.1098/rstb.2014.0116'
chicago: 'Kappeler, Peter, Sylvia Cremer, and Charles Nunn. “Sociality and Health:
Impacts of Sociality on Disease Susceptibility and Transmission in Animal and
Human Societies.” Philosophical Transactions of the Royal Society of London.
Series B, Biological Sciences. Royal Society, 2015. https://doi.org/10.1098/rstb.2014.0116.'
ieee: 'P. Kappeler, S. Cremer, and C. Nunn, “Sociality and health: Impacts of sociality
on disease susceptibility and transmission in animal and human societies,” Philosophical
Transactions of the Royal Society of London. Series B, Biological Sciences,
vol. 370, no. 1669. Royal Society, 2015.'
ista: 'Kappeler P, Cremer S, Nunn C. 2015. Sociality and health: Impacts of sociality
on disease susceptibility and transmission in animal and human societies. Philosophical
Transactions of the Royal Society of London. Series B, Biological Sciences. 370(1669),
20140116.'
mla: 'Kappeler, Peter, et al. “Sociality and Health: Impacts of Sociality on Disease
Susceptibility and Transmission in Animal and Human Societies.” Philosophical
Transactions of the Royal Society of London. Series B, Biological Sciences,
vol. 370, no. 1669, 20140116, Royal Society, 2015, doi:10.1098/rstb.2014.0116.'
short: P. Kappeler, S. Cremer, C. Nunn, Philosophical Transactions of the Royal
Society of London. Series B, Biological Sciences 370 (2015).
date_created: 2018-12-11T11:54:15Z
date_published: 2015-05-01T00:00:00Z
date_updated: 2021-01-12T06:53:29Z
day: '01'
department:
- _id: SyCr
doi: 10.1098/rstb.2014.0116
external_id:
pmid:
- '25870402'
intvolume: ' 370'
issue: '1669'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410382/
month: '05'
oa: 1
oa_version: Submitted Version
pmid: 1
publication: Philosophical Transactions of the Royal Society of London. Series B,
Biological Sciences
publication_status: published
publisher: Royal Society
publist_id: '5272'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Sociality and health: Impacts of sociality on disease susceptibility and transmission
in animal and human societies'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 370
year: '2015'
...
---
_id: '1828'
abstract:
- lang: eng
text: We construct a non-linear Markov process connected with a biological model
of a bacterial genome recombination. The description of invariant measures of
this process gives us the solution of one problem in elementary probability theory.
article_processing_charge: No
author:
- first_name: Arseniy
full_name: Akopyan, Arseniy
id: 430D2C90-F248-11E8-B48F-1D18A9856A87
last_name: Akopyan
orcid: 0000-0002-2548-617X
- first_name: Sergey
full_name: Pirogov, Sergey
last_name: Pirogov
- first_name: Aleksandr
full_name: Rybko, Aleksandr
last_name: Rybko
citation:
ama: Akopyan A, Pirogov S, Rybko A. Invariant measures of genetic recombination
process. Journal of Statistical Physics. 2015;160(1):163-167. doi:10.1007/s10955-015-1238-5
apa: Akopyan, A., Pirogov, S., & Rybko, A. (2015). Invariant measures of genetic
recombination process. Journal of Statistical Physics. Springer. https://doi.org/10.1007/s10955-015-1238-5
chicago: Akopyan, Arseniy, Sergey Pirogov, and Aleksandr Rybko. “Invariant Measures
of Genetic Recombination Process.” Journal of Statistical Physics. Springer,
2015. https://doi.org/10.1007/s10955-015-1238-5.
ieee: A. Akopyan, S. Pirogov, and A. Rybko, “Invariant measures of genetic recombination
process,” Journal of Statistical Physics, vol. 160, no. 1. Springer, pp.
163–167, 2015.
ista: Akopyan A, Pirogov S, Rybko A. 2015. Invariant measures of genetic recombination
process. Journal of Statistical Physics. 160(1), 163–167.
mla: Akopyan, Arseniy, et al. “Invariant Measures of Genetic Recombination Process.”
Journal of Statistical Physics, vol. 160, no. 1, Springer, 2015, pp. 163–67,
doi:10.1007/s10955-015-1238-5.
short: A. Akopyan, S. Pirogov, A. Rybko, Journal of Statistical Physics 160 (2015)
163–167.
date_created: 2018-12-11T11:54:14Z
date_published: 2015-07-01T00:00:00Z
date_updated: 2021-01-12T06:53:28Z
day: '01'
department:
- _id: HeEd
doi: 10.1007/s10955-015-1238-5
ec_funded: 1
intvolume: ' 160'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: arxiv.org/abs/1406.5313
month: '07'
oa: 1
oa_version: Preprint
page: 163 - 167
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Journal of Statistical Physics
publication_status: published
publisher: Springer
publist_id: '5276'
quality_controlled: '1'
scopus_import: 1
status: public
title: Invariant measures of genetic recombination process
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 160
year: '2015'
...
---
_id: '1836'
abstract:
- lang: eng
text: In the standard framework for worst-case execution time (WCET) analysis of
programs, the main data structure is a single instance of integer linear programming
(ILP) that represents the whole program. The instance of this NP-hard problem
must be solved to find an estimate forWCET, and it must be refined if the estimate
is not tight.We propose a new framework for WCET analysis, based on abstract segment
trees (ASTs) as the main data structure. The ASTs have two advantages. First,
they allow computing WCET by solving a number of independent small ILP instances.
Second, ASTs store more expressive constraints, thus enabling a more efficient
and precise refinement procedure. In order to realize our framework algorithmically,
we develop an algorithm for WCET estimation on ASTs, and we develop an interpolation-based
counterexample-guided refinement scheme for ASTs. Furthermore, we extend our framework
to obtain parametric estimates of WCET. We experimentally evaluate our approach
on a set of examples from WCET benchmark suites and linear-algebra packages. We
show that our analysis, with comparable effort, provides WCET estimates that in
many cases significantly improve those computed by existing tools.
alternative_title:
- LNCS
author:
- first_name: Pavol
full_name: Cerny, Pavol
id: 4DCBEFFE-F248-11E8-B48F-1D18A9856A87
last_name: Cerny
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Laura
full_name: Kovács, Laura
last_name: Kovács
- first_name: Arjun
full_name: Radhakrishna, Arjun
id: 3B51CAC4-F248-11E8-B48F-1D18A9856A87
last_name: Radhakrishna
- first_name: Jakob
full_name: Zwirchmayr, Jakob
last_name: Zwirchmayr
citation:
ama: Cerny P, Henzinger TA, Kovács L, Radhakrishna A, Zwirchmayr J. Segment abstraction
for worst-case execution time analysis. 2015;9032:105-131. doi:10.1007/978-3-662-46669-8_5
apa: 'Cerny, P., Henzinger, T. A., Kovács, L., Radhakrishna, A., & Zwirchmayr,
J. (2015). Segment abstraction for worst-case execution time analysis. Presented
at the ESOP: European Symposium on Programming, London, United Kingdom: Springer.
https://doi.org/10.1007/978-3-662-46669-8_5'
chicago: Cerny, Pavol, Thomas A Henzinger, Laura Kovács, Arjun Radhakrishna, and
Jakob Zwirchmayr. “Segment Abstraction for Worst-Case Execution Time Analysis.”
Lecture Notes in Computer Science. Springer, 2015. https://doi.org/10.1007/978-3-662-46669-8_5.
ieee: P. Cerny, T. A. Henzinger, L. Kovács, A. Radhakrishna, and J. Zwirchmayr,
“Segment abstraction for worst-case execution time analysis,” vol. 9032. Springer,
pp. 105–131, 2015.
ista: Cerny P, Henzinger TA, Kovács L, Radhakrishna A, Zwirchmayr J. 2015. Segment
abstraction for worst-case execution time analysis. 9032, 105–131.
mla: Cerny, Pavol, et al. Segment Abstraction for Worst-Case Execution Time Analysis.
Vol. 9032, Springer, 2015, pp. 105–31, doi:10.1007/978-3-662-46669-8_5.
short: P. Cerny, T.A. Henzinger, L. Kovács, A. Radhakrishna, J. Zwirchmayr, 9032
(2015) 105–131.
conference:
end_date: 2015-04-18
location: London, United Kingdom
name: 'ESOP: European Symposium on Programming'
start_date: 2015-04-11
date_created: 2018-12-11T11:54:16Z
date_published: 2015-04-01T00:00:00Z
date_updated: 2020-08-11T10:09:32Z
day: '01'
department:
- _id: ToHe
doi: 10.1007/978-3-662-46669-8_5
ec_funded: 1
intvolume: ' 9032'
language:
- iso: eng
month: '04'
oa_version: None
page: 105 - 131
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
publication_status: published
publisher: Springer
publist_id: '5266'
quality_controlled: '1'
scopus_import: 1
series_title: Lecture Notes in Computer Science
status: public
title: Segment abstraction for worst-case execution time analysis
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9032
year: '2015'
...
---
_id: '1838'
abstract:
- lang: eng
text: Synthesis of program parts is particularly useful for concurrent systems.
However, most approaches do not support common design tasks, like modifying a
single process without having to re-synthesize or verify the whole system. Assume-guarantee
synthesis (AGS) provides robustness against modifications of system parts, but
thus far has been limited to the perfect information setting. This means that
local variables cannot be hidden from other processes, which renders synthesis
results cumbersome or even impossible to realize.We resolve this shortcoming by
defining AGS under partial information. We analyze the complexity and decidability
in different settings, showing that the problem has a high worstcase complexity
and is undecidable in many interesting cases. Based on these observations, we
present a pragmatic algorithm based on bounded synthesis, and demonstrate its
practical applicability on several examples.
acknowledgement: 'This work was supported by the Austrian Science Fund (FWF) through
the research network RiSE (S11406-N23, S11407-N23) and grant nr. P23499-N23, by
the European Commission through an ERC Start grant (279307: Graph Games) and project
STANCE (317753), as well as by the German Research Foundation (DFG) through SFB/TR
14 AVACS and project ASDPS(JA 2357/2-1).'
alternative_title:
- LNCS
author:
- first_name: Roderick
full_name: Bloem, Roderick
last_name: Bloem
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Swen
full_name: Jacobs, Swen
last_name: Jacobs
- first_name: Robert
full_name: Könighofer, Robert
last_name: Könighofer
citation:
ama: 'Bloem R, Chatterjee K, Jacobs S, Könighofer R. Assume-guarantee synthesis
for concurrent reactive programs with partial information. In: Vol 9035. Springer;
2015:517-532. doi:10.1007/978-3-662-46681-0_50'
apa: 'Bloem, R., Chatterjee, K., Jacobs, S., & Könighofer, R. (2015). Assume-guarantee
synthesis for concurrent reactive programs with partial information (Vol. 9035,
pp. 517–532). Presented at the TACAS: Tools and Algorithms for the Construction
and Analysis of Systems, London, United Kingdom: Springer. https://doi.org/10.1007/978-3-662-46681-0_50'
chicago: Bloem, Roderick, Krishnendu Chatterjee, Swen Jacobs, and Robert Könighofer.
“Assume-Guarantee Synthesis for Concurrent Reactive Programs with Partial Information,”
9035:517–32. Springer, 2015. https://doi.org/10.1007/978-3-662-46681-0_50.
ieee: 'R. Bloem, K. Chatterjee, S. Jacobs, and R. Könighofer, “Assume-guarantee
synthesis for concurrent reactive programs with partial information,” presented
at the TACAS: Tools and Algorithms for the Construction and Analysis of Systems,
London, United Kingdom, 2015, vol. 9035, pp. 517–532.'
ista: 'Bloem R, Chatterjee K, Jacobs S, Könighofer R. 2015. Assume-guarantee synthesis
for concurrent reactive programs with partial information. TACAS: Tools and Algorithms
for the Construction and Analysis of Systems, LNCS, vol. 9035, 517–532.'
mla: Bloem, Roderick, et al. Assume-Guarantee Synthesis for Concurrent Reactive
Programs with Partial Information. Vol. 9035, Springer, 2015, pp. 517–32,
doi:10.1007/978-3-662-46681-0_50.
short: R. Bloem, K. Chatterjee, S. Jacobs, R. Könighofer, in:, Springer, 2015, pp.
517–532.
conference:
end_date: 2015-04-18
location: London, United Kingdom
name: 'TACAS: Tools and Algorithms for the Construction and Analysis of Systems'
start_date: 2015-04-11
date_created: 2018-12-11T11:54:17Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2021-01-12T06:53:32Z
day: '01'
department:
- _id: KrCh
doi: 10.1007/978-3-662-46681-0_50
ec_funded: 1
intvolume: ' 9035'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1411.4604
month: '01'
oa: 1
oa_version: Preprint
page: 517 - 532
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
publication_status: published
publisher: Springer
publist_id: '5264'
scopus_import: 1
status: public
title: Assume-guarantee synthesis for concurrent reactive programs with partial information
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9035
year: '2015'
...
---
_id: '1839'
abstract:
- lang: eng
text: We present MultiGain, a tool to synthesize strategies for Markov decision
processes (MDPs) with multiple mean-payoff objectives. Our models are described
in PRISM, and our tool uses the existing interface and simulator of PRISM. Our
tool extends PRISM by adding novel algorithms for multiple mean-payoff objectives,
and also provides features such as (i) generating strategies and exploring them
for simulation, and checking them with respect to other properties; and (ii) generating
an approximate Pareto curve for two mean-payoff objectives. In addition, we present
a new practical algorithm for the analysis of MDPs with multiple mean-payoff objectives
under memoryless strategies.
alternative_title:
- LNCS
author:
- first_name: Tomáš
full_name: Brázdil, Tomáš
last_name: Brázdil
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Vojtěch
full_name: Forejt, Vojtěch
last_name: Forejt
- first_name: Antonín
full_name: Kučera, Antonín
last_name: Kučera
citation:
ama: 'Brázdil T, Chatterjee K, Forejt V, Kučera A. Multigain: A controller synthesis
tool for MDPs with multiple mean-payoff objectives. 2015;9035:181-187. doi:10.1007/978-3-662-46681-0_12'
apa: 'Brázdil, T., Chatterjee, K., Forejt, V., & Kučera, A. (2015). Multigain:
A controller synthesis tool for MDPs with multiple mean-payoff objectives. Presented
at the TACAS: Tools and Algorithms for the Construction and Analysis of Systems,
London, United Kingdom: Springer. https://doi.org/10.1007/978-3-662-46681-0_12'
chicago: 'Brázdil, Tomáš, Krishnendu Chatterjee, Vojtěch Forejt, and Antonín Kučera.
“Multigain: A Controller Synthesis Tool for MDPs with Multiple Mean-Payoff Objectives.”
Lecture Notes in Computer Science. Springer, 2015. https://doi.org/10.1007/978-3-662-46681-0_12.'
ieee: 'T. Brázdil, K. Chatterjee, V. Forejt, and A. Kučera, “Multigain: A controller
synthesis tool for MDPs with multiple mean-payoff objectives,” vol. 9035. Springer,
pp. 181–187, 2015.'
ista: 'Brázdil T, Chatterjee K, Forejt V, Kučera A. 2015. Multigain: A controller
synthesis tool for MDPs with multiple mean-payoff objectives. 9035, 181–187.'
mla: 'Brázdil, Tomáš, et al. Multigain: A Controller Synthesis Tool for MDPs
with Multiple Mean-Payoff Objectives. Vol. 9035, Springer, 2015, pp. 181–87,
doi:10.1007/978-3-662-46681-0_12.'
short: T. Brázdil, K. Chatterjee, V. Forejt, A. Kučera, 9035 (2015) 181–187.
conference:
end_date: 2015-04-18
location: London, United Kingdom
name: 'TACAS: Tools and Algorithms for the Construction and Analysis of Systems'
start_date: 2015-04-11
date_created: 2018-12-11T11:54:18Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2020-01-21T13:18:52Z
day: '01'
department:
- _id: KrCh
doi: 10.1007/978-3-662-46681-0_12
ec_funded: 1
intvolume: ' 9035'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1501.03093
month: '01'
oa: 1
oa_version: Preprint
page: 181 - 187
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
publication_status: published
publisher: Springer
publist_id: '5263'
quality_controlled: '1'
series_title: Lecture Notes in Computer Science
status: public
title: 'Multigain: A controller synthesis tool for MDPs with multiple mean-payoff
objectives'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9035
year: '2015'
...
---
_id: '1837'
abstract:
- lang: eng
text: 'Transition to turbulence in straight pipes occurs in spite of the linear
stability of the laminar Hagen-Poiseuille flow if both the amplitude of flow perturbations
and the Reynolds number Re exceed a minimum threshold (subcritical transition).
As the pipe curvature increases, centrifugal effects become important, modifying
the basic flow as well as the most unstable linear modes. If the curvature (tube-to-coiling
diameter d/D) is sufficiently large, a Hopf bifurcation (supercritical instability)
is encountered before turbulence can be excited (subcritical instability). We
trace the instability thresholds in the Re - d/D parameter space in the range
0.01 ≤ d/D\ ≤ 0.1 by means of laser-Doppler velocimetry and determine the point
where the subcritical and supercritical instabilities meet. Two different experimental
set-ups are used: a closed system where the pipe forms an axisymmetric torus and
an open system employing a helical pipe. Implications for the measurement of friction
factors in curved pipes are discussed.'
article_number: R3
article_processing_charge: No
article_type: original
author:
- first_name: Jakob
full_name: Kühnen, Jakob
id: 3A47AE32-F248-11E8-B48F-1D18A9856A87
last_name: Kühnen
orcid: 0000-0003-4312-0179
- first_name: P
full_name: Braunshier, P
last_name: Braunshier
- first_name: M
full_name: Schwegel, M
last_name: Schwegel
- first_name: Hendrik
full_name: Kuhlmann, Hendrik
last_name: Kuhlmann
- first_name: Björn
full_name: Hof, Björn
id: 3A374330-F248-11E8-B48F-1D18A9856A87
last_name: Hof
orcid: 0000-0003-2057-2754
citation:
ama: Kühnen J, Braunshier P, Schwegel M, Kuhlmann H, Hof B. Subcritical versus supercritical
transition to turbulence in curved pipes. Journal of Fluid Mechanics. 2015;770(5).
doi:10.1017/jfm.2015.184
apa: Kühnen, J., Braunshier, P., Schwegel, M., Kuhlmann, H., & Hof, B. (2015).
Subcritical versus supercritical transition to turbulence in curved pipes. Journal
of Fluid Mechanics. Cambridge University Press. https://doi.org/10.1017/jfm.2015.184
chicago: Kühnen, Jakob, P Braunshier, M Schwegel, Hendrik Kuhlmann, and Björn Hof.
“Subcritical versus Supercritical Transition to Turbulence in Curved Pipes.” Journal
of Fluid Mechanics. Cambridge University Press, 2015. https://doi.org/10.1017/jfm.2015.184.
ieee: J. Kühnen, P. Braunshier, M. Schwegel, H. Kuhlmann, and B. Hof, “Subcritical
versus supercritical transition to turbulence in curved pipes,” Journal of
Fluid Mechanics, vol. 770, no. 5. Cambridge University Press, 2015.
ista: Kühnen J, Braunshier P, Schwegel M, Kuhlmann H, Hof B. 2015. Subcritical versus
supercritical transition to turbulence in curved pipes. Journal of Fluid Mechanics.
770(5), R3.
mla: Kühnen, Jakob, et al. “Subcritical versus Supercritical Transition to Turbulence
in Curved Pipes.” Journal of Fluid Mechanics, vol. 770, no. 5, R3, Cambridge
University Press, 2015, doi:10.1017/jfm.2015.184.
short: J. Kühnen, P. Braunshier, M. Schwegel, H. Kuhlmann, B. Hof, Journal of Fluid
Mechanics 770 (2015).
date_created: 2018-12-11T11:54:17Z
date_published: 2015-04-08T00:00:00Z
date_updated: 2021-01-12T06:53:31Z
day: '08'
department:
- _id: BjHo
doi: 10.1017/jfm.2015.184
ec_funded: 1
external_id:
arxiv:
- '1508.06559'
intvolume: ' 770'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1508.06559
month: '04'
oa: 1
oa_version: Preprint
project:
- _id: 25152F3A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '306589'
name: Decoding the complexity of turbulence at its origin
publication: Journal of Fluid Mechanics
publication_status: published
publisher: Cambridge University Press
publist_id: '5265'
quality_controlled: '1'
scopus_import: 1
status: public
title: Subcritical versus supercritical transition to turbulence in curved pipes
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 770
year: '2015'
...
---
_id: '1848'
abstract:
- lang: eng
text: The ability to escape apoptosis is a hallmark of cancer-initiating cells and
a key factor of resistance to oncolytic therapy. Here, we identify FAM96A as a
ubiquitous, evolutionarily conserved apoptosome-activating protein and investigate
its potential pro-apoptotic tumor suppressor function in gastrointestinal stromal
tumors (GISTs). Interaction between FAM96A and apoptotic peptidase activating
factor 1 (APAF1) was identified in yeast two-hybrid screen and further studied
by deletion mutants, glutathione-S-transferase pull-down, co-immunoprecipitation
and immunofluorescence. Effects of FAM96A overexpression and knock-down on apoptosis
sensitivity were examined in cancer cells and zebrafish embryos. Expression of
FAM96A in GISTs and histogenetically related cells including interstitial cells
of Cajal (ICCs), “fibroblast-like cells” (FLCs) and ICC stem cells (ICC-SCs) was
investigated by Northern blotting, reverse transcription—polymerase chain reaction,
immunohistochemistry and Western immunoblotting. Tumorigenicity of GIST cells
and transformed murine ICC-SCs stably transduced to re-express FAM96A was studied
by xeno- and allografting into immunocompromised mice. FAM96A was found to bind
APAF1 and to enhance the induction of mitochondrial apoptosis. FAM96A protein
or mRNA was dramatically reduced or lost in 106 of 108 GIST samples representing
three independent patient cohorts. Whereas ICCs, ICC-SCs and FLCs, the presumed
normal counterparts of GIST, were found to robustly express FAM96A protein and
mRNA, FAM96A expression was much reduced in tumorigenic ICC-SCs. Re-expression
of FAM96A in GIST cells and transformed ICC-SCs increased apoptosis sensitivity
and diminished tumorigenicity. Our data suggest FAM96A is a novel pro-apoptotic
tumor suppressor that is lost during GIST tumorigenesis.
article_processing_charge: No
article_type: original
author:
- first_name: Bettina
full_name: Schwamb, Bettina
last_name: Schwamb
- first_name: Robert
full_name: Pick, Robert
last_name: Pick
- first_name: Sara
full_name: Fernández, Sara
last_name: Fernández
- first_name: Kirsten
full_name: Völp, Kirsten
last_name: Völp
- first_name: Jan
full_name: Heering, Jan
last_name: Heering
- first_name: Volker
full_name: Dötsch, Volker
last_name: Dötsch
- first_name: Susanne
full_name: Bösser, Susanne
last_name: Bösser
- first_name: Jennifer
full_name: Jung, Jennifer
last_name: Jung
- first_name: Rasa
full_name: Beinoravičiute Kellner, Rasa
last_name: Beinoravičiute Kellner
- first_name: Josephine
full_name: Wesely, Josephine
last_name: Wesely
- first_name: Inka
full_name: Zörnig, Inka
last_name: Zörnig
- first_name: Matthias
full_name: Hammerschmidt, Matthias
last_name: Hammerschmidt
- first_name: Matthias
full_name: Nowak, Matthias
id: 30845DAA-F248-11E8-B48F-1D18A9856A87
last_name: Nowak
- first_name: Roland
full_name: Penzel, Roland
last_name: Penzel
- first_name: Kurt
full_name: Zatloukal, Kurt
last_name: Zatloukal
- first_name: Stefan
full_name: Joos, Stefan
last_name: Joos
- first_name: Ralf
full_name: Rieker, Ralf
last_name: Rieker
- first_name: Abbas
full_name: Agaimy, Abbas
last_name: Agaimy
- first_name: Stephan
full_name: Söder, Stephan
last_name: Söder
- first_name: Kmarie
full_name: Reid Lombardo, Kmarie
last_name: Reid Lombardo
- first_name: Michael
full_name: Kendrick, Michael
last_name: Kendrick
- first_name: Michael
full_name: Bardsley, Michael
last_name: Bardsley
- first_name: Yujiro
full_name: Hayashi, Yujiro
last_name: Hayashi
- first_name: David
full_name: Asuzu, David
last_name: Asuzu
- first_name: Sabriya
full_name: Syed, Sabriya
last_name: Syed
- first_name: Tamás
full_name: Ördög, Tamás
last_name: Ördög
- first_name: Martin
full_name: Zörnig, Martin
last_name: Zörnig
citation:
ama: Schwamb B, Pick R, Fernández S, et al. FAM96A is a novel pro-apoptotic tumor
suppressor in gastrointestinal stromal tumors. International Journal of Cancer.
2015;137(6):1318-1329. doi:10.1002/ijc.29498
apa: Schwamb, B., Pick, R., Fernández, S., Völp, K., Heering, J., Dötsch, V., …
Zörnig, M. (2015). FAM96A is a novel pro-apoptotic tumor suppressor in gastrointestinal
stromal tumors. International Journal of Cancer. Wiley. https://doi.org/10.1002/ijc.29498
chicago: Schwamb, Bettina, Robert Pick, Sara Fernández, Kirsten Völp, Jan Heering,
Volker Dötsch, Susanne Bösser, et al. “FAM96A Is a Novel Pro-Apoptotic Tumor Suppressor
in Gastrointestinal Stromal Tumors.” International Journal of Cancer. Wiley,
2015. https://doi.org/10.1002/ijc.29498.
ieee: B. Schwamb et al., “FAM96A is a novel pro-apoptotic tumor suppressor
in gastrointestinal stromal tumors,” International Journal of Cancer, vol.
137, no. 6. Wiley, pp. 1318–1329, 2015.
ista: Schwamb B, Pick R, Fernández S, Völp K, Heering J, Dötsch V, Bösser S, Jung
J, Beinoravičiute Kellner R, Wesely J, Zörnig I, Hammerschmidt M, Nowak M, Penzel
R, Zatloukal K, Joos S, Rieker R, Agaimy A, Söder S, Reid Lombardo K, Kendrick
M, Bardsley M, Hayashi Y, Asuzu D, Syed S, Ördög T, Zörnig M. 2015. FAM96A is
a novel pro-apoptotic tumor suppressor in gastrointestinal stromal tumors. International
Journal of Cancer. 137(6), 1318–1329.
mla: Schwamb, Bettina, et al. “FAM96A Is a Novel Pro-Apoptotic Tumor Suppressor
in Gastrointestinal Stromal Tumors.” International Journal of Cancer, vol.
137, no. 6, Wiley, 2015, pp. 1318–29, doi:10.1002/ijc.29498.
short: B. Schwamb, R. Pick, S. Fernández, K. Völp, J. Heering, V. Dötsch, S. Bösser,
J. Jung, R. Beinoravičiute Kellner, J. Wesely, I. Zörnig, M. Hammerschmidt, M.
Nowak, R. Penzel, K. Zatloukal, S. Joos, R. Rieker, A. Agaimy, S. Söder, K. Reid
Lombardo, M. Kendrick, M. Bardsley, Y. Hayashi, D. Asuzu, S. Syed, T. Ördög, M.
Zörnig, International Journal of Cancer 137 (2015) 1318–1329.
date_created: 2018-12-11T11:54:20Z
date_published: 2015-09-01T00:00:00Z
date_updated: 2021-01-12T06:53:36Z
day: '01'
department:
- _id: LifeSc
doi: 10.1002/ijc.29498
external_id:
pmid:
- '25716227'
intvolume: ' 137'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497860/
month: '09'
oa: 1
oa_version: Submitted Version
page: 1318 - 1329
pmid: 1
publication: International Journal of Cancer
publication_status: published
publisher: Wiley
publist_id: '5253'
quality_controlled: '1'
scopus_import: 1
status: public
title: FAM96A is a novel pro-apoptotic tumor suppressor in gastrointestinal stromal
tumors
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 137
year: '2015'
...
---
_id: '1846'
abstract:
- lang: eng
text: Modal transition systems (MTS) is a well-studied specification formalism of
reactive systems supporting a step-wise refinement methodology. Despite its many
advantages, the formalism as well as its currently known extensions are incapable
of expressing some practically needed aspects in the refinement process like exclusive,
conditional and persistent choices. We introduce a new model called parametric
modal transition systems (PMTS) together with a general modal refinement notion
that overcomes many of the limitations. We investigate the computational complexity
of modal and thorough refinement checking on PMTS and its subclasses and provide
a direct encoding of the modal refinement problem into quantified Boolean formulae,
allowing us to employ state-of-the-art QBF solvers for modal refinement checking.
The experiments we report on show that the feasibility of refinement checking
is more influenced by the degree of nondeterminism rather than by the syntactic
restrictions on the types of formulae allowed in the description of the PMTS.
article_processing_charge: No
article_type: original
author:
- first_name: Nikola
full_name: Beneš, Nikola
last_name: Beneš
- first_name: Jan
full_name: Kretinsky, Jan
id: 44CEF464-F248-11E8-B48F-1D18A9856A87
last_name: Kretinsky
orcid: 0000-0002-8122-2881
- first_name: Kim
full_name: Larsen, Kim
last_name: Larsen
- first_name: Mikael
full_name: Möller, Mikael
last_name: Möller
- first_name: Salomon
full_name: Sickert, Salomon
last_name: Sickert
- first_name: Jiří
full_name: Srba, Jiří
last_name: Srba
citation:
ama: Beneš N, Kretinsky J, Larsen K, Möller M, Sickert S, Srba J. Refinement checking
on parametric modal transition systems. Acta Informatica. 2015;52(2-3):269-297.
doi:10.1007/s00236-015-0215-4
apa: Beneš, N., Kretinsky, J., Larsen, K., Möller, M., Sickert, S., & Srba,
J. (2015). Refinement checking on parametric modal transition systems. Acta
Informatica. Springer. https://doi.org/10.1007/s00236-015-0215-4
chicago: Beneš, Nikola, Jan Kretinsky, Kim Larsen, Mikael Möller, Salomon Sickert,
and Jiří Srba. “Refinement Checking on Parametric Modal Transition Systems.” Acta
Informatica. Springer, 2015. https://doi.org/10.1007/s00236-015-0215-4.
ieee: N. Beneš, J. Kretinsky, K. Larsen, M. Möller, S. Sickert, and J. Srba, “Refinement
checking on parametric modal transition systems,” Acta Informatica, vol.
52, no. 2–3. Springer, pp. 269–297, 2015.
ista: Beneš N, Kretinsky J, Larsen K, Möller M, Sickert S, Srba J. 2015. Refinement
checking on parametric modal transition systems. Acta Informatica. 52(2–3), 269–297.
mla: Beneš, Nikola, et al. “Refinement Checking on Parametric Modal Transition Systems.”
Acta Informatica, vol. 52, no. 2–3, Springer, 2015, pp. 269–97, doi:10.1007/s00236-015-0215-4.
short: N. Beneš, J. Kretinsky, K. Larsen, M. Möller, S. Sickert, J. Srba, Acta Informatica
52 (2015) 269–297.
date_created: 2018-12-11T11:54:20Z
date_published: 2015-04-01T00:00:00Z
date_updated: 2021-01-12T06:53:35Z
day: '01'
ddc:
- '000'
department:
- _id: ToHe
- _id: KrCh
doi: 10.1007/s00236-015-0215-4
ec_funded: 1
file:
- access_level: open_access
checksum: fb4037ddc4fc05f33080dd3547ede350
content_type: application/pdf
creator: dernst
date_created: 2020-05-15T08:57:44Z
date_updated: 2020-07-14T12:45:19Z
file_id: '7854'
file_name: 2015_ActaInfo_Benes.pdf
file_size: 488482
relation: main_file
file_date_updated: 2020-07-14T12:45:19Z
has_accepted_license: '1'
intvolume: ' 52'
issue: 2-3
language:
- iso: eng
month: '04'
oa: 1
oa_version: Submitted Version
page: 269 - 297
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
publication: Acta Informatica
publication_status: published
publisher: Springer
publist_id: '5255'
quality_controlled: '1'
scopus_import: 1
status: public
title: Refinement checking on parametric modal transition systems
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 52
year: '2015'
...
---
_id: '1845'
abstract:
- lang: eng
text: Based on extrapolation from excitatory synapses, it is often assumed that
depletion of the releasable pool of synaptic vesicles is the main factor underlying
depression at inhibitory synapses. In this issue of Neuron, using subcellular
patch-clamp recording from inhibitory presynaptic terminals, Kawaguchi and Sakaba
(2015) show that at Purkinje cell-deep cerebellar nuclei neuron synapses, changes
in presynaptic action potential waveform substantially contribute to synaptic
depression. Based on extrapolation from excitatory synapses, it is often assumed
that depletion of the releasable pool of synaptic vesicles is the main factor
underlying depression at inhibitory synapses. In this issue of Neuron, using subcellular
patch-clamp recording from inhibitory presynaptic terminals, Kawaguchi and Sakaba
(2015) show that at Purkinje cell-deep cerebellar nuclei neuron synapses, changes
in presynaptic action potential waveform substantially contribute to synaptic
depression.
article_processing_charge: No
author:
- first_name: David H
full_name: Vandael, David H
id: 3AE48E0A-F248-11E8-B48F-1D18A9856A87
last_name: Vandael
orcid: 0000-0001-7577-1676
- first_name: 'Claudia '
full_name: 'Espinoza Martinez, Claudia '
id: 31FFEE2E-F248-11E8-B48F-1D18A9856A87
last_name: Espinoza Martinez
orcid: 0000-0003-4710-2082
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Vandael DH, Espinoza Martinez C, Jonas PM. Excitement about inhibitory presynaptic
terminals. Neuron. 2015;85(6):1149-1151. doi:10.1016/j.neuron.2015.03.006
apa: Vandael, D. H., Espinoza Martinez, C., & Jonas, P. M. (2015). Excitement
about inhibitory presynaptic terminals. Neuron. Elsevier. https://doi.org/10.1016/j.neuron.2015.03.006
chicago: Vandael, David H, Claudia Espinoza Martinez, and Peter M Jonas. “Excitement
about Inhibitory Presynaptic Terminals.” Neuron. Elsevier, 2015. https://doi.org/10.1016/j.neuron.2015.03.006.
ieee: D. H. Vandael, C. Espinoza Martinez, and P. M. Jonas, “Excitement about inhibitory
presynaptic terminals,” Neuron, vol. 85, no. 6. Elsevier, pp. 1149–1151,
2015.
ista: Vandael DH, Espinoza Martinez C, Jonas PM. 2015. Excitement about inhibitory
presynaptic terminals. Neuron. 85(6), 1149–1151.
mla: Vandael, David H., et al. “Excitement about Inhibitory Presynaptic Terminals.”
Neuron, vol. 85, no. 6, Elsevier, 2015, pp. 1149–51, doi:10.1016/j.neuron.2015.03.006.
short: D.H. Vandael, C. Espinoza Martinez, P.M. Jonas, Neuron 85 (2015) 1149–1151.
date_created: 2018-12-11T11:54:19Z
date_published: 2015-03-18T00:00:00Z
date_updated: 2021-10-08T09:07:34Z
day: '18'
ddc:
- '570'
department:
- _id: PeJo
doi: 10.1016/j.neuron.2015.03.006
file:
- access_level: open_access
checksum: d1808550e376a0eca2a950fda017cfa6
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:16:07Z
date_updated: 2020-07-14T12:45:19Z
file_id: '5192'
file_name: IST-2017-822-v1+1_Perspective_Fig__Final.pdf
file_size: 411832
relation: main_file
- access_level: open_access
checksum: a279f4ae61e6c8f33d68f69a0d02097d
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:16:07Z
date_updated: 2020-07-14T12:45:19Z
file_id: '5193'
file_name: IST-2017-822-v1+2_Perspective_Final2.pdf
file_size: 100769
relation: main_file
file_date_updated: 2020-07-14T12:45:19Z
has_accepted_license: '1'
intvolume: ' 85'
issue: '6'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 1149 - 1151
publication: Neuron
publication_status: published
publisher: Elsevier
publist_id: '5256'
pubrep_id: '822'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Excitement about inhibitory presynaptic terminals
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 85
year: '2015'
...
---
_id: '1840'
abstract:
- lang: eng
text: In this paper, we present a method for reducing a regular, discrete-time Markov
chain (DTMC) to another DTMC with a given, typically much smaller number of states.
The cost of reduction is defined as the Kullback-Leibler divergence rate between
a projection of the original process through a partition function and a DTMC on
the correspondingly partitioned state space. Finding the reduced model with minimal
cost is computationally expensive, as it requires an exhaustive search among all
state space partitions, and an exact evaluation of the reduction cost for each
candidate partition. Our approach deals with the latter problem by minimizing
an upper bound on the reduction cost instead of minimizing the exact cost. The
proposed upper bound is easy to compute and it is tight if the original chain
is lumpable with respect to the partition. Then, we express the problem in the
form of information bottleneck optimization, and propose using the agglomerative
information bottleneck algorithm for searching a suboptimal partition greedily,
rather than exhaustively. The theory is illustrated with examples and one application
scenario in the context of modeling bio-molecular interactions.
acknowledgement: "This work was supported by the Austrian Research Association under
Project 06/12684, by the Swiss National Science Foundation (SNSF) under Grant PP00P2
128503/1, by the SystemsX.ch (the Swiss Inititative for Systems Biology), and by
a SNSF Early Postdoc.Mobility Fellowship grant P2EZP2_148797.\r\n"
author:
- first_name: Bernhard
full_name: Geiger, Bernhard
last_name: Geiger
- first_name: Tatjana
full_name: Petrov, Tatjana
id: 3D5811FC-F248-11E8-B48F-1D18A9856A87
last_name: Petrov
orcid: 0000-0002-9041-0905
- first_name: Gernot
full_name: Kubin, Gernot
last_name: Kubin
- first_name: Heinz
full_name: Koeppl, Heinz
last_name: Koeppl
citation:
ama: Geiger B, Petrov T, Kubin G, Koeppl H. Optimal Kullback-Leibler aggregation
via information bottleneck. IEEE Transactions on Automatic Control. 2015;60(4):1010-1022.
doi:10.1109/TAC.2014.2364971
apa: Geiger, B., Petrov, T., Kubin, G., & Koeppl, H. (2015). Optimal Kullback-Leibler
aggregation via information bottleneck. IEEE Transactions on Automatic Control.
IEEE. https://doi.org/10.1109/TAC.2014.2364971
chicago: Geiger, Bernhard, Tatjana Petrov, Gernot Kubin, and Heinz Koeppl. “Optimal
Kullback-Leibler Aggregation via Information Bottleneck.” IEEE Transactions
on Automatic Control. IEEE, 2015. https://doi.org/10.1109/TAC.2014.2364971.
ieee: B. Geiger, T. Petrov, G. Kubin, and H. Koeppl, “Optimal Kullback-Leibler aggregation
via information bottleneck,” IEEE Transactions on Automatic Control, vol.
60, no. 4. IEEE, pp. 1010–1022, 2015.
ista: Geiger B, Petrov T, Kubin G, Koeppl H. 2015. Optimal Kullback-Leibler aggregation
via information bottleneck. IEEE Transactions on Automatic Control. 60(4), 1010–1022.
mla: Geiger, Bernhard, et al. “Optimal Kullback-Leibler Aggregation via Information
Bottleneck.” IEEE Transactions on Automatic Control, vol. 60, no. 4, IEEE,
2015, pp. 1010–22, doi:10.1109/TAC.2014.2364971.
short: B. Geiger, T. Petrov, G. Kubin, H. Koeppl, IEEE Transactions on Automatic
Control 60 (2015) 1010–1022.
date_created: 2018-12-11T11:54:18Z
date_published: 2015-04-01T00:00:00Z
date_updated: 2021-01-12T06:53:33Z
day: '01'
department:
- _id: CaGu
- _id: ToHe
doi: 10.1109/TAC.2014.2364971
intvolume: ' 60'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1304.6603
month: '04'
oa: 1
oa_version: Preprint
page: 1010 - 1022
publication: IEEE Transactions on Automatic Control
publication_identifier:
issn:
- 0018-9286
publication_status: published
publisher: IEEE
publist_id: '5262'
quality_controlled: '1'
scopus_import: 1
status: public
title: Optimal Kullback-Leibler aggregation via information bottleneck
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 60
year: '2015'
...
---
_id: '1841'
abstract:
- lang: eng
text: We propose a new family of message passing techniques for MAP estimation in
graphical models which we call Sequential Reweighted Message Passing (SRMP). Special
cases include well-known techniques such as Min-Sum Diffusion (MSD) and a faster
Sequential Tree-Reweighted Message Passing (TRW-S). Importantly, our derivation
is simpler than the original derivation of TRW-S, and does not involve a decomposition
into trees. This allows easy generalizations. The new family of algorithms can
be viewed as a generalization of TRW-S from pairwise to higher-order graphical
models. We test SRMP on several real-world problems with promising results.
author:
- first_name: Vladimir
full_name: Kolmogorov, Vladimir
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
citation:
ama: Kolmogorov V. A new look at reweighted message passing. IEEE Transactions
on Pattern Analysis and Machine Intelligence. 2015;37(5):919-930. doi:10.1109/TPAMI.2014.2363465
apa: Kolmogorov, V. (2015). A new look at reweighted message passing. IEEE Transactions
on Pattern Analysis and Machine Intelligence. IEEE. https://doi.org/10.1109/TPAMI.2014.2363465
chicago: Kolmogorov, Vladimir. “A New Look at Reweighted Message Passing.” IEEE
Transactions on Pattern Analysis and Machine Intelligence. IEEE, 2015. https://doi.org/10.1109/TPAMI.2014.2363465.
ieee: V. Kolmogorov, “A new look at reweighted message passing,” IEEE Transactions
on Pattern Analysis and Machine Intelligence, vol. 37, no. 5. IEEE, pp. 919–930,
2015.
ista: Kolmogorov V. 2015. A new look at reweighted message passing. IEEE Transactions
on Pattern Analysis and Machine Intelligence. 37(5), 919–930.
mla: Kolmogorov, Vladimir. “A New Look at Reweighted Message Passing.” IEEE Transactions
on Pattern Analysis and Machine Intelligence, vol. 37, no. 5, IEEE, 2015,
pp. 919–30, doi:10.1109/TPAMI.2014.2363465.
short: V. Kolmogorov, IEEE Transactions on Pattern Analysis and Machine Intelligence
37 (2015) 919–930.
date_created: 2018-12-11T11:54:18Z
date_published: 2015-05-01T00:00:00Z
date_updated: 2021-01-12T06:53:33Z
day: '01'
department:
- _id: VlKo
doi: 10.1109/TPAMI.2014.2363465
ec_funded: 1
intvolume: ' 37'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1309.5655
month: '05'
oa: 1
oa_version: Preprint
page: 919 - 930
project:
- _id: 25FBA906-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '616160'
name: 'Discrete Optimization in Computer Vision: Theory and Practice'
publication: IEEE Transactions on Pattern Analysis and Machine Intelligence
publication_status: published
publisher: IEEE
publist_id: '5261'
quality_controlled: '1'
scopus_import: 1
status: public
title: A new look at reweighted message passing
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 37
year: '2015'
...
---
_id: '1849'
abstract:
- lang: eng
text: 'Cell polarity is a fundamental property of pro- and eukaryotic cells. It
is necessary for coordination of cell division, cell morphogenesis and signaling
processes. How polarity is generated and maintained is a complex issue governed
by interconnected feed-back regulations between small GTPase signaling and membrane
tension-based signaling that controls membrane trafficking, and cytoskeleton organization
and dynamics. Here, we will review the potential role for calcium as a crucial
signal that connects and coordinates the respective processes during polarization
processes in plants. This article is part of a Special Issue entitled: 13th European
Symposium on Calcium.'
acknowledgement: The contributing authors were supported by the Ghent University Special
Research Fund (to E.H.), the Interuniversity Attraction Poles Programme (IAP VI/33
and IUAP P7/29 ‘MARS’), the European Research Council (project ERC-2011-StG-20101109-PSDP,
to J.F.), and the Research Foundation Flanders (to S.V.).
author:
- first_name: Ellie
full_name: Himschoot, Ellie
last_name: Himschoot
- first_name: Tom
full_name: Beeckman, Tom
last_name: Beeckman
- first_name: Jiřĺ
full_name: Friml, Jiřĺ
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Steffen
full_name: Vanneste, Steffen
last_name: Vanneste
citation:
ama: Himschoot E, Beeckman T, Friml J, Vanneste S. Calcium is an organizer of cell
polarity in plants. Biochimica et Biophysica Acta - Molecular Cell Research.
2015;1853(9):2168-2172. doi:10.1016/j.bbamcr.2015.02.017
apa: Himschoot, E., Beeckman, T., Friml, J., & Vanneste, S. (2015). Calcium
is an organizer of cell polarity in plants. Biochimica et Biophysica Acta -
Molecular Cell Research. Elsevier. https://doi.org/10.1016/j.bbamcr.2015.02.017
chicago: Himschoot, Ellie, Tom Beeckman, Jiří Friml, and Steffen Vanneste. “Calcium
Is an Organizer of Cell Polarity in Plants.” Biochimica et Biophysica Acta
- Molecular Cell Research. Elsevier, 2015. https://doi.org/10.1016/j.bbamcr.2015.02.017.
ieee: E. Himschoot, T. Beeckman, J. Friml, and S. Vanneste, “Calcium is an organizer
of cell polarity in plants,” Biochimica et Biophysica Acta - Molecular Cell
Research, vol. 1853, no. 9. Elsevier, pp. 2168–2172, 2015.
ista: Himschoot E, Beeckman T, Friml J, Vanneste S. 2015. Calcium is an organizer
of cell polarity in plants. Biochimica et Biophysica Acta - Molecular Cell Research.
1853(9), 2168–2172.
mla: Himschoot, Ellie, et al. “Calcium Is an Organizer of Cell Polarity in Plants.”
Biochimica et Biophysica Acta - Molecular Cell Research, vol. 1853, no.
9, Elsevier, 2015, pp. 2168–72, doi:10.1016/j.bbamcr.2015.02.017.
short: E. Himschoot, T. Beeckman, J. Friml, S. Vanneste, Biochimica et Biophysica
Acta - Molecular Cell Research 1853 (2015) 2168–2172.
date_created: 2018-12-11T11:54:21Z
date_published: 2015-09-01T00:00:00Z
date_updated: 2021-01-12T06:53:36Z
day: '01'
department:
- _id: JiFr
doi: 10.1016/j.bbamcr.2015.02.017
intvolume: ' 1853'
issue: '9'
language:
- iso: eng
month: '09'
oa_version: None
page: 2168 - 2172
publication: Biochimica et Biophysica Acta - Molecular Cell Research
publication_status: published
publisher: Elsevier
publist_id: '5252'
quality_controlled: '1'
scopus_import: 1
status: public
title: Calcium is an organizer of cell polarity in plants
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1853
year: '2015'
...
---
_id: '1847'
acknowledgement: This work was supported by the European Research Council (project
ERC-2011-StG-20101109-PSDP), European Social Fund (CZ.1.07/2.3.00/20.0043), and
the Czech Science Foundation GAČR (GA13-40637S).
author:
- first_name: Peter
full_name: Grones, Peter
id: 399876EC-F248-11E8-B48F-1D18A9856A87
last_name: Grones
- first_name: Jiřĺ
full_name: Friml, Jiřĺ
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: 'Grones P, Friml J. ABP1: Finally docking. Molecular Plant. 2015;8(3):356-358.
doi:10.1016/j.molp.2014.12.013'
apa: 'Grones, P., & Friml, J. (2015). ABP1: Finally docking. Molecular Plant.
Elsevier. https://doi.org/10.1016/j.molp.2014.12.013'
chicago: 'Grones, Peter, and Jiří Friml. “ABP1: Finally Docking.” Molecular Plant.
Elsevier, 2015. https://doi.org/10.1016/j.molp.2014.12.013.'
ieee: 'P. Grones and J. Friml, “ABP1: Finally docking,” Molecular Plant,
vol. 8, no. 3. Elsevier, pp. 356–358, 2015.'
ista: 'Grones P, Friml J. 2015. ABP1: Finally docking. Molecular Plant. 8(3), 356–358.'
mla: 'Grones, Peter, and Jiří Friml. “ABP1: Finally Docking.” Molecular Plant,
vol. 8, no. 3, Elsevier, 2015, pp. 356–58, doi:10.1016/j.molp.2014.12.013.'
short: P. Grones, J. Friml, Molecular Plant 8 (2015) 356–358.
date_created: 2018-12-11T11:54:20Z
date_published: 2015-03-02T00:00:00Z
date_updated: 2021-01-12T06:53:35Z
day: '02'
department:
- _id: JiFr
doi: 10.1016/j.molp.2014.12.013
intvolume: ' 8'
issue: '3'
language:
- iso: eng
month: '03'
oa_version: None
page: 356 - 358
publication: Molecular Plant
publication_status: published
publisher: Elsevier
publist_id: '5254'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'ABP1: Finally docking'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2015'
...
---
_id: '1850'
abstract:
- lang: eng
text: 'Entomopathogenic fungi are potent biocontrol agents that are widely used
against insect pests, many of which are social insects. Nevertheless, theoretical
investigations of their particular life history are scarce. We develop a model
that takes into account the main distinguishing features between traditionally
studied diseases and obligate killing pathogens, like the (biocontrol-relevant)
insect-pathogenic fungi Metarhizium and Beauveria. First, obligate killing entomopathogenic
fungi produce new infectious particles (conidiospores) only after host death and
not yet on the living host. Second, the killing rates of entomopathogenic fungi
depend strongly on the initial exposure dosage, thus we explicitly consider the
pathogen load of individual hosts. Further, we make the model applicable not only
to solitary host species, but also to group living species by incorporating social
interactions between hosts, like the collective disease defences of insect societies.
Our results identify the optimal killing rate for the pathogen that minimises
its invasion threshold. Furthermore, we find that the rate of contact between
hosts has an ambivalent effect: dense interaction networks between individuals
are considered to facilitate disease outbreaks because of increased pathogen transmission.
In social insects, this is compensated by their collective disease defences, i.e.,
social immunity. For the type of pathogens considered here, we show that even
without social immunity, high contact rates between live individuals dilute the
pathogen in the host colony and hence can reduce individual pathogen loads below
disease-causing levels.'
author:
- first_name: Sebastian
full_name: Novak, Sebastian
id: 461468AE-F248-11E8-B48F-1D18A9856A87
last_name: Novak
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
citation:
ama: 'Novak S, Cremer S. Fungal disease dynamics in insect societies: Optimal killing
rates and the ambivalent effect of high social interaction rates. Journal of
Theoretical Biology. 2015;372(5):54-64. doi:10.1016/j.jtbi.2015.02.018'
apa: 'Novak, S., & Cremer, S. (2015). Fungal disease dynamics in insect societies:
Optimal killing rates and the ambivalent effect of high social interaction rates.
Journal of Theoretical Biology. Elsevier. https://doi.org/10.1016/j.jtbi.2015.02.018'
chicago: 'Novak, Sebastian, and Sylvia Cremer. “Fungal Disease Dynamics in Insect
Societies: Optimal Killing Rates and the Ambivalent Effect of High Social Interaction
Rates.” Journal of Theoretical Biology. Elsevier, 2015. https://doi.org/10.1016/j.jtbi.2015.02.018.'
ieee: 'S. Novak and S. Cremer, “Fungal disease dynamics in insect societies: Optimal
killing rates and the ambivalent effect of high social interaction rates,” Journal
of Theoretical Biology, vol. 372, no. 5. Elsevier, pp. 54–64, 2015.'
ista: 'Novak S, Cremer S. 2015. Fungal disease dynamics in insect societies: Optimal
killing rates and the ambivalent effect of high social interaction rates. Journal
of Theoretical Biology. 372(5), 54–64.'
mla: 'Novak, Sebastian, and Sylvia Cremer. “Fungal Disease Dynamics in Insect Societies:
Optimal Killing Rates and the Ambivalent Effect of High Social Interaction Rates.”
Journal of Theoretical Biology, vol. 372, no. 5, Elsevier, 2015, pp. 54–64,
doi:10.1016/j.jtbi.2015.02.018.'
short: S. Novak, S. Cremer, Journal of Theoretical Biology 372 (2015) 54–64.
date_created: 2018-12-11T11:54:21Z
date_published: 2015-05-07T00:00:00Z
date_updated: 2021-01-12T06:53:37Z
day: '07'
ddc:
- '576'
department:
- _id: NiBa
- _id: SyCr
doi: 10.1016/j.jtbi.2015.02.018
ec_funded: 1
file:
- access_level: open_access
checksum: 3c0dcacc900bc45cc65a453dfda4ca43
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:18:07Z
date_updated: 2020-07-14T12:45:19Z
file_id: '5326'
file_name: IST-2015-329-v1+1_manuscript.pdf
file_size: 1546914
relation: main_file
file_date_updated: 2020-07-14T12:45:19Z
has_accepted_license: '1'
intvolume: ' 372'
issue: '5'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Submitted Version
page: 54 - 64
project:
- _id: 25B07788-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '250152'
name: Limits to selection in biology and in evolutionary computation
- _id: 25DC711C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '243071'
name: 'Social Vaccination in Ant Colonies: from Individual Mechanisms to Society
Effects'
publication: Journal of Theoretical Biology
publication_status: published
publisher: Elsevier
publist_id: '5251'
pubrep_id: '329'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Fungal disease dynamics in insect societies: Optimal killing rates and the
ambivalent effect of high social interaction rates'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 372
year: '2015'
...
---
_id: '1851'
abstract:
- lang: eng
text: We consider mating strategies for females who search for males sequentially
during a season of limited length. We show that the best strategy rejects a given
male type if encountered before a time-threshold but accepts him after. For frequency-independent
benefits, we obtain the optimal time-thresholds explicitly for both discrete and
continuous distributions of males, and allow for mistakes being made in assessing
the correct male type. When the benefits are indirect (genes for the offspring)
and the population is under frequency-dependent ecological selection, the benefits
depend on the mating strategy of other females as well. This case is particularly
relevant to speciation models that seek to explore the stability of reproductive
isolation by assortative mating under frequency-dependent ecological selection.
We show that the indirect benefits are to be quantified by the reproductive values
of couples, and describe how the evolutionarily stable time-thresholds can be
found. We conclude with an example based on the Levene model, in which we analyze
the evolutionarily stable assortative mating strategies and the strength of reproductive
isolation provided by them.
article_processing_charge: No
article_type: original
author:
- first_name: Tadeas
full_name: Priklopil, Tadeas
id: 3C869AA0-F248-11E8-B48F-1D18A9856A87
last_name: Priklopil
- first_name: Eva
full_name: Kisdi, Eva
last_name: Kisdi
- first_name: Mats
full_name: Gyllenberg, Mats
last_name: Gyllenberg
citation:
ama: Priklopil T, Kisdi E, Gyllenberg M. Evolutionarily stable mating decisions
for sequentially searching females and the stability of reproductive isolation
by assortative mating. Evolution. 2015;69(4):1015-1026. doi:10.1111/evo.12618
apa: Priklopil, T., Kisdi, E., & Gyllenberg, M. (2015). Evolutionarily stable
mating decisions for sequentially searching females and the stability of reproductive
isolation by assortative mating. Evolution. Wiley. https://doi.org/10.1111/evo.12618
chicago: Priklopil, Tadeas, Eva Kisdi, and Mats Gyllenberg. “Evolutionarily Stable
Mating Decisions for Sequentially Searching Females and the Stability of Reproductive
Isolation by Assortative Mating.” Evolution. Wiley, 2015. https://doi.org/10.1111/evo.12618.
ieee: T. Priklopil, E. Kisdi, and M. Gyllenberg, “Evolutionarily stable mating decisions
for sequentially searching females and the stability of reproductive isolation
by assortative mating,” Evolution, vol. 69, no. 4. Wiley, pp. 1015–1026,
2015.
ista: Priklopil T, Kisdi E, Gyllenberg M. 2015. Evolutionarily stable mating decisions
for sequentially searching females and the stability of reproductive isolation
by assortative mating. Evolution. 69(4), 1015–1026.
mla: Priklopil, Tadeas, et al. “Evolutionarily Stable Mating Decisions for Sequentially
Searching Females and the Stability of Reproductive Isolation by Assortative Mating.”
Evolution, vol. 69, no. 4, Wiley, 2015, pp. 1015–26, doi:10.1111/evo.12618.
short: T. Priklopil, E. Kisdi, M. Gyllenberg, Evolution 69 (2015) 1015–1026.
date_created: 2018-12-11T11:54:21Z
date_published: 2015-02-09T00:00:00Z
date_updated: 2022-06-07T10:52:37Z
day: '09'
ddc:
- '570'
department:
- _id: NiBa
- _id: KrCh
doi: 10.1111/evo.12618
ec_funded: 1
external_id:
pmid:
- '25662095'
file:
- access_level: open_access
checksum: 1e8be0b1d7598a78cd2623d8ee8e7798
content_type: application/pdf
creator: dernst
date_created: 2020-05-15T09:05:34Z
date_updated: 2020-07-14T12:45:19Z
file_id: '7855'
file_name: 2015_Evolution_Priklopil.pdf
file_size: 967214
relation: main_file
file_date_updated: 2020-07-14T12:45:19Z
has_accepted_license: '1'
intvolume: ' 69'
issue: '4'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Submitted Version
page: 1015 - 1026
pmid: 1
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Evolution
publication_identifier:
eissn:
- 1558-5646
issn:
- 0014-3820
publication_status: published
publisher: Wiley
publist_id: '5249'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Evolutionarily stable mating decisions for sequentially searching females and
the stability of reproductive isolation by assortative mating
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 69
year: '2015'
...
---
_id: '1859'
abstract:
- lang: eng
text: "Structural support vector machines (SSVMs) are amongst the best performing
models for structured computer vision tasks, such as semantic image segmentation
or human pose estimation. Training SSVMs, however, is computationally costly,
because it requires repeated calls to a structured prediction subroutine (called
\\emph{max-oracle}), which has to solve an optimization problem itself, e.g. a
graph cut.\r\nIn this work, we introduce a new algorithm for SSVM training that
is more efficient than earlier techniques when the max-oracle is computationally
expensive, as it is frequently the case in computer vision tasks. The main idea
is to (i) combine the recent stochastic Block-Coordinate Frank-Wolfe algorithm
with efficient hyperplane caching, and (ii) use an automatic selection rule for
deciding whether to call the exact max-oracle or to rely on an approximate one
based on the cached hyperplanes.\r\nWe show experimentally that this strategy
leads to faster convergence to the optimum with respect to the number of requires
oracle calls, and that this translates into faster convergence with respect to
the total runtime when the max-oracle is slow compared to the other steps of the
algorithm. "
author:
- first_name: Neel
full_name: Shah, Neel
id: 31ABAF80-F248-11E8-B48F-1D18A9856A87
last_name: Shah
- first_name: Vladimir
full_name: Kolmogorov, Vladimir
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
citation:
ama: 'Shah N, Kolmogorov V, Lampert C. A multi-plane block-coordinate Frank-Wolfe
algorithm for training structural SVMs with a costly max-oracle. In: IEEE; 2015:2737-2745.
doi:10.1109/CVPR.2015.7298890'
apa: 'Shah, N., Kolmogorov, V., & Lampert, C. (2015). A multi-plane block-coordinate
Frank-Wolfe algorithm for training structural SVMs with a costly max-oracle (pp.
2737–2745). Presented at the CVPR: Computer Vision and Pattern Recognition, Boston,
MA, USA: IEEE. https://doi.org/10.1109/CVPR.2015.7298890'
chicago: Shah, Neel, Vladimir Kolmogorov, and Christoph Lampert. “A Multi-Plane
Block-Coordinate Frank-Wolfe Algorithm for Training Structural SVMs with a Costly
Max-Oracle,” 2737–45. IEEE, 2015. https://doi.org/10.1109/CVPR.2015.7298890.
ieee: 'N. Shah, V. Kolmogorov, and C. Lampert, “A multi-plane block-coordinate Frank-Wolfe
algorithm for training structural SVMs with a costly max-oracle,” presented at
the CVPR: Computer Vision and Pattern Recognition, Boston, MA, USA, 2015, pp.
2737–2745.'
ista: 'Shah N, Kolmogorov V, Lampert C. 2015. A multi-plane block-coordinate Frank-Wolfe
algorithm for training structural SVMs with a costly max-oracle. CVPR: Computer
Vision and Pattern Recognition, 2737–2745.'
mla: Shah, Neel, et al. A Multi-Plane Block-Coordinate Frank-Wolfe Algorithm
for Training Structural SVMs with a Costly Max-Oracle. IEEE, 2015, pp. 2737–45,
doi:10.1109/CVPR.2015.7298890.
short: N. Shah, V. Kolmogorov, C. Lampert, in:, IEEE, 2015, pp. 2737–2745.
conference:
end_date: 2015-06-12
location: Boston, MA, USA
name: 'CVPR: Computer Vision and Pattern Recognition'
start_date: 2015-06-07
date_created: 2018-12-11T11:54:24Z
date_published: 2015-06-01T00:00:00Z
date_updated: 2021-01-12T06:53:40Z
day: '01'
department:
- _id: VlKo
- _id: ChLa
doi: 10.1109/CVPR.2015.7298890
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1408.6804
month: '06'
oa: 1
oa_version: Preprint
page: 2737 - 2745
project:
- _id: 2532554C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '308036'
name: Lifelong Learning of Visual Scene Understanding
- _id: 25FBA906-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '616160'
name: 'Discrete Optimization in Computer Vision: Theory and Practice'
publication_status: published
publisher: IEEE
publist_id: '5240'
quality_controlled: '1'
scopus_import: 1
status: public
title: A multi-plane block-coordinate Frank-Wolfe algorithm for training structural
SVMs with a costly max-oracle
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '1860'
abstract:
- lang: eng
text: Classifiers for object categorization are usually evaluated by their accuracy
on a set of i.i.d. test examples. This provides us with an estimate of the expected
error when applying the classifiers to a single new image. In real application,
however, classifiers are rarely only used for a single image and then discarded.
Instead, they are applied sequentially to many images, and these are typically
not i.i.d. samples from a fixed data distribution, but they carry dependencies
and their class distribution varies over time. In this work, we argue that the
phenomenon of correlated data at prediction time is not a nuisance, but a blessing
in disguise. We describe a probabilistic method for adapting classifiers at prediction
time without having to retrain them. We also introduce a framework for creating
realistically distributed image sequences, which offers a way to benchmark classifier
adaptation methods, such as the one we propose. Experiments on the ILSVRC2010
and ILSVRC2012 datasets show that adapting object classification systems at prediction
time can significantly reduce their error rate, even with no additional human
feedback.
author:
- first_name: Amélie
full_name: Royer, Amélie
last_name: Royer
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
citation:
ama: 'Royer A, Lampert C. Classifier adaptation at prediction time. In: IEEE; 2015:1401-1409.
doi:10.1109/CVPR.2015.7298746'
apa: 'Royer, A., & Lampert, C. (2015). Classifier adaptation at prediction time
(pp. 1401–1409). Presented at the CVPR: Computer Vision and Pattern Recognition,
Boston, MA, United States: IEEE. https://doi.org/10.1109/CVPR.2015.7298746'
chicago: Royer, Amélie, and Christoph Lampert. “Classifier Adaptation at Prediction
Time,” 1401–9. IEEE, 2015. https://doi.org/10.1109/CVPR.2015.7298746.
ieee: 'A. Royer and C. Lampert, “Classifier adaptation at prediction time,” presented
at the CVPR: Computer Vision and Pattern Recognition, Boston, MA, United States,
2015, pp. 1401–1409.'
ista: 'Royer A, Lampert C. 2015. Classifier adaptation at prediction time. CVPR:
Computer Vision and Pattern Recognition, 1401–1409.'
mla: Royer, Amélie, and Christoph Lampert. Classifier Adaptation at Prediction
Time. IEEE, 2015, pp. 1401–09, doi:10.1109/CVPR.2015.7298746.
short: A. Royer, C. Lampert, in:, IEEE, 2015, pp. 1401–1409.
conference:
end_date: 2015-06-12
location: Boston, MA, United States
name: 'CVPR: Computer Vision and Pattern Recognition'
start_date: 2015-06-07
date_created: 2018-12-11T11:54:24Z
date_published: 2015-06-01T00:00:00Z
date_updated: 2021-01-12T06:53:41Z
day: '01'
department:
- _id: ChLa
doi: 10.1109/CVPR.2015.7298746
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.cv-foundation.org/openaccess/content_cvpr_2015/papers/Royer_Classifier_Adaptation_at_2015_CVPR_paper.pdf
month: '06'
oa: 1
oa_version: Submitted Version
page: 1401 - 1409
project:
- _id: 2532554C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '308036'
name: Lifelong Learning of Visual Scene Understanding
publication_status: published
publisher: IEEE
publist_id: '5239'
quality_controlled: '1'
scopus_import: 1
status: public
title: Classifier adaptation at prediction time
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '1858'
abstract:
- lang: eng
text: 'We study the problem of predicting the future, though only in the probabilistic
sense of estimating a future state of a time-varying probability distribution.
This is not only an interesting academic problem, but solving this extrapolation
problem also has many practical application, e.g. for training classifiers that
have to operate under time-varying conditions. Our main contribution is a method
for predicting the next step of the time-varying distribution from a given sequence
of sample sets from earlier time steps. For this we rely on two recent machine
learning techniques: embedding probability distributions into a reproducing kernel
Hilbert space, and learning operators by vector-valued regression. We illustrate
the working principles and the practical usefulness of our method by experiments
on synthetic and real data. We also highlight an exemplary application: training
a classifier in a domain adaptation setting without having access to examples
from the test time distribution at training time.'
author:
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
citation:
ama: 'Lampert C. Predicting the future behavior of a time-varying probability distribution.
In: IEEE; 2015:942-950. doi:10.1109/CVPR.2015.7298696'
apa: 'Lampert, C. (2015). Predicting the future behavior of a time-varying probability
distribution (pp. 942–950). Presented at the CVPR: Computer Vision and Pattern
Recognition, Boston, MA, United States: IEEE. https://doi.org/10.1109/CVPR.2015.7298696'
chicago: Lampert, Christoph. “Predicting the Future Behavior of a Time-Varying Probability
Distribution,” 942–50. IEEE, 2015. https://doi.org/10.1109/CVPR.2015.7298696.
ieee: 'C. Lampert, “Predicting the future behavior of a time-varying probability
distribution,” presented at the CVPR: Computer Vision and Pattern Recognition,
Boston, MA, United States, 2015, pp. 942–950.'
ista: 'Lampert C. 2015. Predicting the future behavior of a time-varying probability
distribution. CVPR: Computer Vision and Pattern Recognition, 942–950.'
mla: Lampert, Christoph. Predicting the Future Behavior of a Time-Varying Probability
Distribution. IEEE, 2015, pp. 942–50, doi:10.1109/CVPR.2015.7298696.
short: C. Lampert, in:, IEEE, 2015, pp. 942–950.
conference:
end_date: 2015-06-12
location: Boston, MA, United States
name: 'CVPR: Computer Vision and Pattern Recognition'
start_date: 2015-06-07
date_created: 2018-12-11T11:54:24Z
date_published: 2015-10-15T00:00:00Z
date_updated: 2021-01-12T06:53:40Z
day: '15'
department:
- _id: ChLa
doi: 10.1109/CVPR.2015.7298696
external_id:
arxiv:
- '1406.5362'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1406.5362
month: '10'
oa: 1
oa_version: Preprint
page: 942 - 950
publication_status: published
publisher: IEEE
publist_id: '5241'
quality_controlled: '1'
scopus_import: 1
status: public
title: Predicting the future behavior of a time-varying probability distribution
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '1857'
abstract:
- lang: eng
text: 'Sharing information between multiple tasks enables algorithms to achieve
good generalization performance even from small amounts of training data. However,
in a realistic scenario of multi-task learning not all tasks are equally related
to each other, hence it could be advantageous to transfer information only between
the most related tasks. In this work we propose an approach that processes multiple
tasks in a sequence with sharing between subsequent tasks instead of solving all
tasks jointly. Subsequently, we address the question of curriculum learning of
tasks, i.e. finding the best order of tasks to be learned. Our approach is based
on a generalization bound criterion for choosing the task order that optimizes
the average expected classification performance over all tasks. Our experimental
results show that learning multiple related tasks sequentially can be more effective
than learning them jointly, the order in which tasks are being solved affects
the overall performance, and that our model is able to automatically discover
the favourable order of tasks. '
author:
- first_name: Anastasia
full_name: Pentina, Anastasia
id: 42E87FC6-F248-11E8-B48F-1D18A9856A87
last_name: Pentina
- first_name: Viktoriia
full_name: Sharmanska, Viktoriia
id: 2EA6D09E-F248-11E8-B48F-1D18A9856A87
last_name: Sharmanska
orcid: 0000-0003-0192-9308
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
citation:
ama: 'Pentina A, Sharmanska V, Lampert C. Curriculum learning of multiple tasks.
In: IEEE; 2015:5492-5500. doi:10.1109/CVPR.2015.7299188'
apa: 'Pentina, A., Sharmanska, V., & Lampert, C. (2015). Curriculum learning
of multiple tasks (pp. 5492–5500). Presented at the CVPR: Computer Vision and
Pattern Recognition, Boston, MA, United States: IEEE. https://doi.org/10.1109/CVPR.2015.7299188'
chicago: Pentina, Anastasia, Viktoriia Sharmanska, and Christoph Lampert. “Curriculum
Learning of Multiple Tasks,” 5492–5500. IEEE, 2015. https://doi.org/10.1109/CVPR.2015.7299188.
ieee: 'A. Pentina, V. Sharmanska, and C. Lampert, “Curriculum learning of multiple
tasks,” presented at the CVPR: Computer Vision and Pattern Recognition, Boston,
MA, United States, 2015, pp. 5492–5500.'
ista: 'Pentina A, Sharmanska V, Lampert C. 2015. Curriculum learning of multiple
tasks. CVPR: Computer Vision and Pattern Recognition, 5492–5500.'
mla: Pentina, Anastasia, et al. Curriculum Learning of Multiple Tasks. IEEE,
2015, pp. 5492–500, doi:10.1109/CVPR.2015.7299188.
short: A. Pentina, V. Sharmanska, C. Lampert, in:, IEEE, 2015, pp. 5492–5500.
conference:
end_date: 2015-06-12
location: Boston, MA, United States
name: 'CVPR: Computer Vision and Pattern Recognition'
start_date: 2015-06-07
date_created: 2018-12-11T11:54:23Z
date_published: 2015-06-01T00:00:00Z
date_updated: 2023-02-23T10:17:31Z
day: '01'
department:
- _id: ChLa
doi: 10.1109/CVPR.2015.7299188
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1412.1353
month: '06'
oa: 1
oa_version: Preprint
page: 5492 - 5500
publication_status: published
publisher: IEEE
publist_id: '5243'
quality_controlled: '1'
scopus_import: 1
status: public
title: Curriculum learning of multiple tasks
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '1867'
abstract:
- lang: eng
text: Cultured mammalian cells essential are model systems in basic biology research,
production platforms of proteins for medical use, and testbeds in synthetic biology.
Flavin cofactors, in particular flavin mononucleotide (FMN) and flavin adenine
dinucleotide (FAD), are critical for cellular redox reactions and sense light
in naturally occurring photoreceptors and optogenetic tools. Here, we quantified
flavin contents of commonly used mammalian cell lines. We first compared three
procedures for extraction of free and noncovalently protein-bound flavins and
verified extraction using fluorescence spectroscopy. For separation, two CE methods
with different BGEs were established, and detection was performed by LED-induced
fluorescence with limit of detections (LODs 0.5-3.8 nM). We found that riboflavin
(RF), FMN, and FAD contents varied significantly between cell lines. RF (3.1-14
amol/cell) and FAD (2.2-17.0 amol/cell) were the predominant flavins, while FMN
(0.46-3.4 amol/cell) was found at markedly lower levels. Observed flavin contents
agree with those previously extracted from mammalian tissues, yet reduced forms
of RF were detected that were not described previously. Quantification of flavins
in mammalian cell lines will allow a better understanding of cellular redox reactions
and optogenetic tools.
author:
- first_name: Jens
full_name: Hühner, Jens
last_name: Hühner
- first_name: Álvaro
full_name: Inglés Prieto, Álvaro
id: 2A9DB292-F248-11E8-B48F-1D18A9856A87
last_name: Inglés Prieto
orcid: 0000-0002-5409-8571
- first_name: Christian
full_name: Neusüß, Christian
last_name: Neusüß
- first_name: Michael
full_name: Lämmerhofer, Michael
last_name: Lämmerhofer
- first_name: Harald L
full_name: Janovjak, Harald L
id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
last_name: Janovjak
orcid: 0000-0002-8023-9315
citation:
ama: Hühner J, Inglés Prieto Á, Neusüß C, Lämmerhofer M, Janovjak HL. Quantification
of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in mammalian
model cells by CE with LED-induced fluorescence detection. Electrophoresis.
2015;36(4):518-525. doi:10.1002/elps.201400451
apa: Hühner, J., Inglés Prieto, Á., Neusüß, C., Lämmerhofer, M., & Janovjak,
H. L. (2015). Quantification of riboflavin, flavin mononucleotide, and flavin
adenine dinucleotide in mammalian model cells by CE with LED-induced fluorescence
detection. Electrophoresis. Wiley. https://doi.org/10.1002/elps.201400451
chicago: Hühner, Jens, Álvaro Inglés Prieto, Christian Neusüß, Michael Lämmerhofer,
and Harald L Janovjak. “Quantification of Riboflavin, Flavin Mononucleotide, and
Flavin Adenine Dinucleotide in Mammalian Model Cells by CE with LED-Induced Fluorescence
Detection.” Electrophoresis. Wiley, 2015. https://doi.org/10.1002/elps.201400451.
ieee: J. Hühner, Á. Inglés Prieto, C. Neusüß, M. Lämmerhofer, and H. L. Janovjak,
“Quantification of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide
in mammalian model cells by CE with LED-induced fluorescence detection,” Electrophoresis,
vol. 36, no. 4. Wiley, pp. 518–525, 2015.
ista: Hühner J, Inglés Prieto Á, Neusüß C, Lämmerhofer M, Janovjak HL. 2015. Quantification
of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide in mammalian
model cells by CE with LED-induced fluorescence detection. Electrophoresis. 36(4),
518–525.
mla: Hühner, Jens, et al. “Quantification of Riboflavin, Flavin Mononucleotide,
and Flavin Adenine Dinucleotide in Mammalian Model Cells by CE with LED-Induced
Fluorescence Detection.” Electrophoresis, vol. 36, no. 4, Wiley, 2015,
pp. 518–25, doi:10.1002/elps.201400451.
short: J. Hühner, Á. Inglés Prieto, C. Neusüß, M. Lämmerhofer, H.L. Janovjak, Electrophoresis
36 (2015) 518–525.
date_created: 2018-12-11T11:54:26Z
date_published: 2015-02-01T00:00:00Z
date_updated: 2021-01-12T06:53:43Z
day: '01'
department:
- _id: HaJa
doi: 10.1002/elps.201400451
ec_funded: 1
intvolume: ' 36'
issue: '4'
language:
- iso: eng
month: '02'
oa_version: None
page: 518 - 525
project:
- _id: 25548C20-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '303564'
name: Microbial Ion Channels for Synthetic Neurobiology
- _id: 255BFFFA-B435-11E9-9278-68D0E5697425
grant_number: RGY0084/2012
name: In situ real-time imaging of neurotransmitter signaling using designer optical
sensors (HFSP Young Investigator)
publication: Electrophoresis
publication_status: published
publisher: Wiley
publist_id: '5230'
pubrep_id: '836'
quality_controlled: '1'
scopus_import: 1
status: public
title: Quantification of riboflavin, flavin mononucleotide, and flavin adenine dinucleotide
in mammalian model cells by CE with LED-induced fluorescence detection
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 36
year: '2015'
...
---
_id: '1865'
abstract:
- lang: eng
text: The plant hormone auxin and its directional transport are known to play a
crucial role in defining the embryonic axis and subsequent development of the
body plan. Although the role of PIN auxin efflux transporters has been clearly
assigned during embryonic shoot and root specification, the role of the auxin
influx carriers AUX1 and LIKE-AUX1 (LAX) proteins is not well established. Here,
we used chemical and genetic tools on Brassica napus microspore-derived embryos
and Arabidopsis thaliana zygotic embryos, and demonstrate that AUX1, LAX1 and
LAX2 are required for both shoot and root pole formation, in concert with PIN
efflux carriers. Furthermore, we uncovered a positive-feedback loop betweenMONOPTEROS(ARF5)-dependent
auxin signalling and auxin transport. ThisMONOPTEROSdependent transcriptional
regulation of auxin influx (AUX1, LAX1 and LAX2) and auxin efflux (PIN1 and PIN4)
carriers by MONOPTEROS helps to maintain proper auxin transport to the root tip.
These results indicate that auxin-dependent cell specification during embryo development
requires balanced auxin transport involving both influx and efflux mechanisms,
and that this transport is maintained by a positive transcriptional feedback on
auxin signalling.
acknowledgement: W.G. is a post-doctoral fellow of the Research Foundation Flanders.
H.S.R. is supported by Employment of Best Young Scientists for International Cooperation
Empowerment [CZ.1.07/2.3.00/30.0037], co-financed by the European Social Fund and
the state budget of the Czech Republic. Mi.S. was funded by the Ramón y Cajal program.
This work was supported by the European Research Council [project ERC-2011-StG-20101109-PSDP],
project ‘CEITEC – Central European Institute of Technology’ [CZ.1.05/1.1.00/02.0068],
the European Social Fund [CZ.1.07/2.3.00/20.0043] and the Czech Science Foundation
GACR [GA13-40637S] to J.F. We acknowledge funding from the Biological and Biotechnological
Science Research Council (BBSRC) and Engineering Physics Science Research Council
(EPSRC) to R.S. and M.B
author:
- first_name: Hélène
full_name: Robert, Hélène
last_name: Robert
- first_name: Wim
full_name: Grunewald, Wim
last_name: Grunewald
- first_name: Michael
full_name: Sauer, Michael
last_name: Sauer
- first_name: Bernard
full_name: Cannoot, Bernard
last_name: Cannoot
- first_name: Mercedes
full_name: Soriano, Mercedes
last_name: Soriano
- first_name: Ranjan
full_name: Swarup, Ranjan
last_name: Swarup
- first_name: Dolf
full_name: Weijers, Dolf
last_name: Weijers
- first_name: Malcolm
full_name: Bennett, Malcolm
last_name: Bennett
- first_name: Kim
full_name: Boutilier, Kim
last_name: Boutilier
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Robert H, Grunewald W, Sauer M, et al. Plant embryogenesis requires AUX/LAX-mediated
auxin influx. Development. 2015;142(4):702-711. doi:10.1242/dev.115832
apa: Robert, H., Grunewald, W., Sauer, M., Cannoot, B., Soriano, M., Swarup, R.,
… Friml, J. (2015). Plant embryogenesis requires AUX/LAX-mediated auxin influx.
Development. Company of Biologists. https://doi.org/10.1242/dev.115832
chicago: Robert, Hélène, Wim Grunewald, Michael Sauer, Bernard Cannoot, Mercedes
Soriano, Ranjan Swarup, Dolf Weijers, Malcolm Bennett, Kim Boutilier, and Jiří
Friml. “Plant Embryogenesis Requires AUX/LAX-Mediated Auxin Influx.” Development.
Company of Biologists, 2015. https://doi.org/10.1242/dev.115832.
ieee: H. Robert et al., “Plant embryogenesis requires AUX/LAX-mediated auxin
influx,” Development, vol. 142, no. 4. Company of Biologists, pp. 702–711,
2015.
ista: Robert H, Grunewald W, Sauer M, Cannoot B, Soriano M, Swarup R, Weijers D,
Bennett M, Boutilier K, Friml J. 2015. Plant embryogenesis requires AUX/LAX-mediated
auxin influx. Development. 142(4), 702–711.
mla: Robert, Hélène, et al. “Plant Embryogenesis Requires AUX/LAX-Mediated Auxin
Influx.” Development, vol. 142, no. 4, Company of Biologists, 2015, pp.
702–11, doi:10.1242/dev.115832.
short: H. Robert, W. Grunewald, M. Sauer, B. Cannoot, M. Soriano, R. Swarup, D.
Weijers, M. Bennett, K. Boutilier, J. Friml, Development 142 (2015) 702–711.
date_created: 2018-12-11T11:54:26Z
date_published: 2015-02-15T00:00:00Z
date_updated: 2021-01-12T06:53:43Z
day: '15'
department:
- _id: JiFr
doi: 10.1242/dev.115832
ec_funded: 1
intvolume: ' 142'
issue: '4'
language:
- iso: eng
month: '02'
oa_version: None
page: 702 - 711
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '282300'
name: Polarity and subcellular dynamics in plants
publication: Development
publication_status: published
publisher: Company of Biologists
publist_id: '5231'
quality_controlled: '1'
scopus_import: 1
status: public
title: Plant embryogenesis requires AUX/LAX-mediated auxin influx
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 142
year: '2015'
...
---
_id: '1868'
abstract:
- lang: eng
text: We investigate high-dimensional nonlinear dynamical systems exhibiting multiple
resonances under adiabatic parameter variations. Our motivations come from experimental
considerations where time-dependent sweeping of parameters is a practical approach
to probing and characterizing the bifurcations of the system. The question is
whether bifurcations so detected are faithful representations of the bifurcations
intrinsic to the original stationary system. Utilizing a harmonically forced,
closed fluid flow system that possesses multiple resonances and solving the Navier-Stokes
equation under proper boundary conditions, we uncover the phenomenon of the early
effect. Specifically, as a control parameter, e.g., the driving frequency, is
adiabatically increased from an initial value, resonances emerge at frequency
values that are lower than those in the corresponding stationary system. The phenomenon
is established by numerical characterization of physical quantities through the
resonances, which include the kinetic energy and the vorticity field, and a heuristic
analysis based on the concept of instantaneous frequency. A simple formula is
obtained which relates the resonance points in the time-dependent and time-independent
systems. Our findings suggest that, in general, any true bifurcation of a nonlinear
dynamical system can be unequivocally uncovered through adiabatic parameter sweeping,
in spite of a shift in the bifurcation point, which is of value to experimental
studies of nonlinear dynamical systems.
article_number: '022906'
author:
- first_name: Youngyong
full_name: Park, Youngyong
last_name: Park
- first_name: Younghae
full_name: Do, Younghae
last_name: Do
- first_name: Sebastian
full_name: Altmeyer, Sebastian
id: 2EE67FDC-F248-11E8-B48F-1D18A9856A87
last_name: Altmeyer
orcid: 0000-0001-5964-0203
- first_name: Yingcheng
full_name: Lai, Yingcheng
last_name: Lai
- first_name: Gyuwon
full_name: Lee, Gyuwon
last_name: Lee
citation:
ama: Park Y, Do Y, Altmeyer S, Lai Y, Lee G. Early effect in time-dependent, high-dimensional
nonlinear dynamical systems with multiple resonances. Physical Review E.
2015;91(2). doi:10.1103/PhysRevE.91.022906
apa: Park, Y., Do, Y., Altmeyer, S., Lai, Y., & Lee, G. (2015). Early effect
in time-dependent, high-dimensional nonlinear dynamical systems with multiple
resonances. Physical Review E. American Physical Society. https://doi.org/10.1103/PhysRevE.91.022906
chicago: Park, Youngyong, Younghae Do, Sebastian Altmeyer, Yingcheng Lai, and Gyuwon
Lee. “Early Effect in Time-Dependent, High-Dimensional Nonlinear Dynamical Systems
with Multiple Resonances.” Physical Review E. American Physical Society,
2015. https://doi.org/10.1103/PhysRevE.91.022906.
ieee: Y. Park, Y. Do, S. Altmeyer, Y. Lai, and G. Lee, “Early effect in time-dependent,
high-dimensional nonlinear dynamical systems with multiple resonances,” Physical
Review E, vol. 91, no. 2. American Physical Society, 2015.
ista: Park Y, Do Y, Altmeyer S, Lai Y, Lee G. 2015. Early effect in time-dependent,
high-dimensional nonlinear dynamical systems with multiple resonances. Physical
Review E. 91(2), 022906.
mla: Park, Youngyong, et al. “Early Effect in Time-Dependent, High-Dimensional Nonlinear
Dynamical Systems with Multiple Resonances.” Physical Review E, vol. 91,
no. 2, 022906, American Physical Society, 2015, doi:10.1103/PhysRevE.91.022906.
short: Y. Park, Y. Do, S. Altmeyer, Y. Lai, G. Lee, Physical Review E 91 (2015).
date_created: 2018-12-11T11:54:27Z
date_published: 2015-02-09T00:00:00Z
date_updated: 2021-01-12T06:53:44Z
day: '09'
department:
- _id: BjHo
doi: 10.1103/PhysRevE.91.022906
intvolume: ' 91'
issue: '2'
language:
- iso: eng
month: '02'
oa_version: None
publication: Physical Review E
publication_identifier:
issn:
- 1539-3755
publication_status: published
publisher: American Physical Society
publist_id: '5229'
quality_controlled: '1'
scopus_import: 1
status: public
title: Early effect in time-dependent, high-dimensional nonlinear dynamical systems
with multiple resonances
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 91
year: '2015'
...
---
_id: '1864'
abstract:
- lang: eng
text: "The Altshuler–Shklovskii formulas (Altshuler and Shklovskii, BZh Eksp Teor
Fiz 91:200, 1986) predict, for any disordered quantum system in the diffusive
regime, a universal power law behaviour for the correlation functions of the mesoscopic
eigenvalue density. In this paper and its companion (Erdős and Knowles, The Altshuler–Shklovskii
formulas for random band matrices I: the unimodular case, 2013), we prove these
formulas for random band matrices. In (Erdős and Knowles, The Altshuler–Shklovskii
formulas for random band matrices I: the unimodular case, 2013) we introduced
a diagrammatic approach and presented robust estimates on general diagrams under
certain simplifying assumptions. In this paper, we remove these assumptions by
giving a general estimate of the subleading diagrams. We also give a precise analysis
of the leading diagrams which give rise to the Altschuler–Shklovskii power laws.
Moreover, we introduce a family of general random band matrices which interpolates
between real symmetric (β = 1) and complex Hermitian (β = 2) models, and track
the transition for the mesoscopic density–density correlation. Finally, we address
the higher-order correlation functions by proving that they behave asymptotically
according to a Gaussian process whose covariance is given by the Altshuler–Shklovskii
formulas.\r\n"
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Antti
full_name: Knowles, Antti
last_name: Knowles
citation:
ama: 'Erdös L, Knowles A. The Altshuler–Shklovskii formulas for random band matrices
II: The general case. Annales Henri Poincare. 2015;16(3):709-799. doi:10.1007/s00023-014-0333-5'
apa: 'Erdös, L., & Knowles, A. (2015). The Altshuler–Shklovskii formulas for
random band matrices II: The general case. Annales Henri Poincare. Springer.
https://doi.org/10.1007/s00023-014-0333-5'
chicago: 'Erdös, László, and Antti Knowles. “The Altshuler–Shklovskii Formulas for
Random Band Matrices II: The General Case.” Annales Henri Poincare. Springer,
2015. https://doi.org/10.1007/s00023-014-0333-5.'
ieee: 'L. Erdös and A. Knowles, “The Altshuler–Shklovskii formulas for random band
matrices II: The general case,” Annales Henri Poincare, vol. 16, no. 3.
Springer, pp. 709–799, 2015.'
ista: 'Erdös L, Knowles A. 2015. The Altshuler–Shklovskii formulas for random band
matrices II: The general case. Annales Henri Poincare. 16(3), 709–799.'
mla: 'Erdös, László, and Antti Knowles. “The Altshuler–Shklovskii Formulas for Random
Band Matrices II: The General Case.” Annales Henri Poincare, vol. 16, no.
3, Springer, 2015, pp. 709–99, doi:10.1007/s00023-014-0333-5.'
short: L. Erdös, A. Knowles, Annales Henri Poincare 16 (2015) 709–799.
date_created: 2018-12-11T11:54:26Z
date_published: 2015-03-01T00:00:00Z
date_updated: 2021-01-12T06:53:42Z
day: '01'
department:
- _id: LaEr
doi: 10.1007/s00023-014-0333-5
ec_funded: 1
intvolume: ' 16'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1309.5107
month: '03'
oa: 1
oa_version: Preprint
page: 709 - 799
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '338804'
name: Random matrices, universality and disordered quantum systems
publication: Annales Henri Poincare
publication_status: published
publisher: Springer
publist_id: '5233'
scopus_import: 1
status: public
title: 'The Altshuler–Shklovskii formulas for random band matrices II: The general
case'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2015'
...
---
_id: '1861'
abstract:
- lang: eng
text: Continuous-time Markov chains are commonly used in practice for modeling biochemical
reaction networks in which the inherent randomness of themolecular interactions
cannot be ignored. This has motivated recent research effort into methods for
parameter inference and experiment design for such models. The major difficulty
is that such methods usually require one to iteratively solve the chemical master
equation that governs the time evolution of the probability distribution of the
system. This, however, is rarely possible, and even approximation techniques remain
limited to relatively small and simple systems. An alternative explored in this
article is to base methods on only some low-order moments of the entire probability
distribution. We summarize the theory behind such moment-based methods for parameter
inference and experiment design and provide new case studies where we investigate
their performance.
acknowledgement: "HYCON2; EC; European Commission\r\n"
article_number: '8'
author:
- first_name: Jakob
full_name: Ruess, Jakob
id: 4A245D00-F248-11E8-B48F-1D18A9856A87
last_name: Ruess
orcid: 0000-0003-1615-3282
- first_name: John
full_name: Lygeros, John
last_name: Lygeros
citation:
ama: Ruess J, Lygeros J. Moment-based methods for parameter inference and experiment
design for stochastic biochemical reaction networks. ACM Transactions on Modeling
and Computer Simulation. 2015;25(2). doi:10.1145/2688906
apa: Ruess, J., & Lygeros, J. (2015). Moment-based methods for parameter inference
and experiment design for stochastic biochemical reaction networks. ACM Transactions
on Modeling and Computer Simulation. ACM. https://doi.org/10.1145/2688906
chicago: Ruess, Jakob, and John Lygeros. “Moment-Based Methods for Parameter Inference
and Experiment Design for Stochastic Biochemical Reaction Networks.” ACM Transactions
on Modeling and Computer Simulation. ACM, 2015. https://doi.org/10.1145/2688906.
ieee: J. Ruess and J. Lygeros, “Moment-based methods for parameter inference and
experiment design for stochastic biochemical reaction networks,” ACM Transactions
on Modeling and Computer Simulation, vol. 25, no. 2. ACM, 2015.
ista: Ruess J, Lygeros J. 2015. Moment-based methods for parameter inference and
experiment design for stochastic biochemical reaction networks. ACM Transactions
on Modeling and Computer Simulation. 25(2), 8.
mla: Ruess, Jakob, and John Lygeros. “Moment-Based Methods for Parameter Inference
and Experiment Design for Stochastic Biochemical Reaction Networks.” ACM Transactions
on Modeling and Computer Simulation, vol. 25, no. 2, 8, ACM, 2015, doi:10.1145/2688906.
short: J. Ruess, J. Lygeros, ACM Transactions on Modeling and Computer Simulation
25 (2015).
date_created: 2018-12-11T11:54:25Z
date_published: 2015-02-01T00:00:00Z
date_updated: 2021-01-12T06:53:41Z
day: '01'
department:
- _id: ToHe
- _id: GaTk
doi: 10.1145/2688906
intvolume: ' 25'
issue: '2'
language:
- iso: eng
month: '02'
oa_version: None
publication: ACM Transactions on Modeling and Computer Simulation
publication_status: published
publisher: ACM
publist_id: '5238'
quality_controlled: '1'
scopus_import: 1
status: public
title: Moment-based methods for parameter inference and experiment design for stochastic
biochemical reaction networks
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 25
year: '2015'
...
---
_id: '1866'
author:
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Jean
full_name: Raskin, Jean
last_name: Raskin
citation:
ama: 'Henzinger TA, Raskin J. The equivalence problem for finite automata: Technical
perspective. Communications of the ACM. 2015;58(2):86-86. doi:10.1145/2701001'
apa: 'Henzinger, T. A., & Raskin, J. (2015). The equivalence problem for finite
automata: Technical perspective. Communications of the ACM. ACM. https://doi.org/10.1145/2701001'
chicago: 'Henzinger, Thomas A, and Jean Raskin. “The Equivalence Problem for Finite
Automata: Technical Perspective.” Communications of the ACM. ACM, 2015.
https://doi.org/10.1145/2701001.'
ieee: 'T. A. Henzinger and J. Raskin, “The equivalence problem for finite automata:
Technical perspective,” Communications of the ACM, vol. 58, no. 2. ACM,
pp. 86–86, 2015.'
ista: 'Henzinger TA, Raskin J. 2015. The equivalence problem for finite automata:
Technical perspective. Communications of the ACM. 58(2), 86–86.'
mla: 'Henzinger, Thomas A., and Jean Raskin. “The Equivalence Problem for Finite
Automata: Technical Perspective.” Communications of the ACM, vol. 58, no.
2, ACM, 2015, pp. 86–86, doi:10.1145/2701001.'
short: T.A. Henzinger, J. Raskin, Communications of the ACM 58 (2015) 86–86.
date_created: 2018-12-11T11:54:26Z
date_published: 2015-01-28T00:00:00Z
date_updated: 2021-01-12T06:53:43Z
day: '28'
department:
- _id: ToHe
doi: 10.1145/2701001
intvolume: ' 58'
issue: '2'
language:
- iso: eng
month: '01'
oa_version: None
page: 86-86
publication: Communications of the ACM
publication_status: published
publisher: ACM
publist_id: '5232'
scopus_import: 1
status: public
title: 'The equivalence problem for finite automata: Technical perspective'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 58
year: '2015'
...
---
_id: '1871'
abstract:
- lang: eng
text: The plant hormone auxin is a key regulator of plant growth and development.
Differences in auxin distribution within tissues are mediated by the polar auxin
transport machinery, and cellular auxin responses occur depending on changes in
cellular auxin levels. Multiple receptor systems at the cell surface and in the
interior operate to sense and interpret fluctuations in auxin distribution that
occur during plant development. Until now, three proteins or protein complexes
that can bind auxin have been identified. SCFTIR1 [a SKP1-cullin-1-F-box complex
that contains transport inhibitor response 1 (TIR1) as the F-box protein] and
S-phase-kinaseassociated protein 2 (SKP2) localize to the nucleus, whereas auxinbinding
protein 1 (ABP1), predominantly associates with the endoplasmic reticulum and
cell surface. In this Cell Science at a Glance article, we summarize recent discoveries
in the field of auxin transport and signaling that have led to the identification
of new components of these pathways, as well as their mutual interaction.
acknowledgement: This work was supported by the European Research Council [project
ERC-2011-StG-20101109-PSDP]; European Social Fund [grant number CZ.1.07/2.3.00/20.0043]
and the Czech Science Foundation GAČR [grant number GA13-40637S]
author:
- first_name: Peter
full_name: Grones, Peter
id: 399876EC-F248-11E8-B48F-1D18A9856A87
last_name: Grones
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Grones P, Friml J. Auxin transporters and binding proteins at a glance. Journal
of Cell Science. 2015;128(1):1-7. doi:10.1242/jcs.159418
apa: Grones, P., & Friml, J. (2015). Auxin transporters and binding proteins
at a glance. Journal of Cell Science. Company of Biologists. https://doi.org/10.1242/jcs.159418
chicago: Grones, Peter, and Jiří Friml. “Auxin Transporters and Binding Proteins
at a Glance.” Journal of Cell Science. Company of Biologists, 2015. https://doi.org/10.1242/jcs.159418.
ieee: P. Grones and J. Friml, “Auxin transporters and binding proteins at a glance,”
Journal of Cell Science, vol. 128, no. 1. Company of Biologists, pp. 1–7,
2015.
ista: Grones P, Friml J. 2015. Auxin transporters and binding proteins at a glance.
Journal of Cell Science. 128(1), 1–7.
mla: Grones, Peter, and Jiří Friml. “Auxin Transporters and Binding Proteins at
a Glance.” Journal of Cell Science, vol. 128, no. 1, Company of Biologists,
2015, pp. 1–7, doi:10.1242/jcs.159418.
short: P. Grones, J. Friml, Journal of Cell Science 128 (2015) 1–7.
date_created: 2018-12-11T11:54:28Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2021-01-12T06:53:45Z
day: '01'
ddc:
- '570'
department:
- _id: JiFr
doi: 10.1242/jcs.159418
file:
- access_level: open_access
checksum: 24c779f4cd9d549ca6833e26f486be27
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:11:00Z
date_updated: 2020-07-14T12:45:19Z
file_id: '4852'
file_name: IST-2016-563-v1+1_1.full.pdf
file_size: 1688844
relation: main_file
file_date_updated: 2020-07-14T12:45:19Z
has_accepted_license: '1'
intvolume: ' 128'
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Submitted Version
page: 1 - 7
publication: Journal of Cell Science
publication_status: published
publisher: Company of Biologists
publist_id: '5225'
pubrep_id: '563'
quality_controlled: '1'
scopus_import: 1
status: public
title: Auxin transporters and binding proteins at a glance
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 128
year: '2015'
...
---
_id: '1874'
abstract:
- lang: eng
text: 'The hippocampal region, comprising the hippocampal formation and the parahippocampal
region, has been one of the most intensively studied parts of the brain for decades.
Better understanding of its functional diversity and complexity has led to an
increased demand for specificity in experimental procedures and manipulations.
In view of the complex 3D structure of the hippocampal region, precisely positioned
experimental approaches require a fine-grained architectural description that
is available and readable to experimentalists lacking detailed anatomical experience.
In this paper, we provide the first cyto- and chemoarchitectural description of
the hippocampal formation and parahippocampal region in the rat at high resolution
and in the three standard sectional planes: coronal, horizontal and sagittal.
The atlas uses a series of adjacent sections stained for neurons and for a number
of chemical marker substances, particularly parvalbumin and calbindin. All the
borders defined in one plane have been cross-checked against their counterparts
in the other two planes. The entire dataset will be made available as a web-based
interactive application through the Rodent Brain WorkBench (http://www.rbwb.org)
which, together with this paper, provides a unique atlas resource.'
author:
- first_name: Charlotte
full_name: Boccara, Charlotte
id: 3FC06552-F248-11E8-B48F-1D18A9856A87
last_name: Boccara
orcid: 0000-0001-7237-5109
- first_name: Lisa
full_name: Kjønigsen, Lisa
last_name: Kjønigsen
- first_name: Ingvild
full_name: Hammer, Ingvild
last_name: Hammer
- first_name: Jan
full_name: Bjaalie, Jan
last_name: Bjaalie
- first_name: Trygve
full_name: Leergaard, Trygve
last_name: Leergaard
- first_name: Menno
full_name: Witter, Menno
last_name: Witter
citation:
ama: Boccara CN, Kjønigsen L, Hammer I, Bjaalie J, Leergaard T, Witter M. A three-plane
architectonic atlas of the rat hippocampal region. Hippocampus. 2015;25(7):838-857.
doi:10.1002/hipo.22407
apa: Boccara, C. N., Kjønigsen, L., Hammer, I., Bjaalie, J., Leergaard, T., &
Witter, M. (2015). A three-plane architectonic atlas of the rat hippocampal region.
Hippocampus. Wiley. https://doi.org/10.1002/hipo.22407
chicago: Boccara, Charlotte N., Lisa Kjønigsen, Ingvild Hammer, Jan Bjaalie, Trygve
Leergaard, and Menno Witter. “A Three-Plane Architectonic Atlas of the Rat Hippocampal
Region.” Hippocampus. Wiley, 2015. https://doi.org/10.1002/hipo.22407.
ieee: C. N. Boccara, L. Kjønigsen, I. Hammer, J. Bjaalie, T. Leergaard, and M. Witter,
“A three-plane architectonic atlas of the rat hippocampal region,” Hippocampus,
vol. 25, no. 7. Wiley, pp. 838–857, 2015.
ista: Boccara CN, Kjønigsen L, Hammer I, Bjaalie J, Leergaard T, Witter M. 2015.
A three-plane architectonic atlas of the rat hippocampal region. Hippocampus.
25(7), 838–857.
mla: Boccara, Charlotte N., et al. “A Three-Plane Architectonic Atlas of the Rat
Hippocampal Region.” Hippocampus, vol. 25, no. 7, Wiley, 2015, pp. 838–57,
doi:10.1002/hipo.22407.
short: C.N. Boccara, L. Kjønigsen, I. Hammer, J. Bjaalie, T. Leergaard, M. Witter,
Hippocampus 25 (2015) 838–857.
date_created: 2018-12-11T11:54:29Z
date_published: 2015-07-01T00:00:00Z
date_updated: 2021-01-12T06:53:46Z
day: '01'
department:
- _id: JoCs
doi: 10.1002/hipo.22407
intvolume: ' 25'
issue: '7'
language:
- iso: eng
month: '07'
oa_version: None
page: 838 - 857
publication: Hippocampus
publication_status: published
publisher: Wiley
publist_id: '5222'
quality_controlled: '1'
scopus_import: 1
status: public
title: A three-plane architectonic atlas of the rat hippocampal region
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 25
year: '2015'
...
---
_id: '1873'
abstract:
- lang: eng
text: 'We consider partially observable Markov decision processes (POMDPs) with
limit-average payoff, where a reward value in the interval [0,1] is associated
with every transition, and the payoff of an infinite path is the long-run average
of the rewards. We consider two types of path constraints: (i) a quantitative
constraint defines the set of paths where the payoff is at least a given threshold
λ1ε(0,1]; and (ii) a qualitative constraint which is a special case of the quantitative
constraint with λ1=1. We consider the computation of the almost-sure winning set,
where the controller needs to ensure that the path constraint is satisfied with
probability 1. Our main results for qualitative path constraints are as follows:
(i) the problem of deciding the existence of a finite-memory controller is EXPTIME-complete;
and (ii) the problem of deciding the existence of an infinite-memory controller
is undecidable. For quantitative path constraints we show that the problem of
deciding the existence of a finite-memory controller is undecidable. We also present
a prototype implementation of our EXPTIME algorithm and experimental results on
several examples.'
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Martin
full_name: Chmelik, Martin
id: 3624234E-F248-11E8-B48F-1D18A9856A87
last_name: Chmelik
citation:
ama: Chatterjee K, Chmelik M. POMDPs under probabilistic semantics. Artificial
Intelligence. 2015;221:46-72. doi:10.1016/j.artint.2014.12.009
apa: Chatterjee, K., & Chmelik, M. (2015). POMDPs under probabilistic semantics.
Artificial Intelligence. Elsevier. https://doi.org/10.1016/j.artint.2014.12.009
chicago: Chatterjee, Krishnendu, and Martin Chmelik. “POMDPs under Probabilistic
Semantics.” Artificial Intelligence. Elsevier, 2015. https://doi.org/10.1016/j.artint.2014.12.009.
ieee: K. Chatterjee and M. Chmelik, “POMDPs under probabilistic semantics,” Artificial
Intelligence, vol. 221. Elsevier, pp. 46–72, 2015.
ista: Chatterjee K, Chmelik M. 2015. POMDPs under probabilistic semantics. Artificial
Intelligence. 221, 46–72.
mla: Chatterjee, Krishnendu, and Martin Chmelik. “POMDPs under Probabilistic Semantics.”
Artificial Intelligence, vol. 221, Elsevier, 2015, pp. 46–72, doi:10.1016/j.artint.2014.12.009.
short: K. Chatterjee, M. Chmelik, Artificial Intelligence 221 (2015) 46–72.
date_created: 2018-12-11T11:54:28Z
date_published: 2015-04-01T00:00:00Z
date_updated: 2021-01-12T06:53:46Z
day: '01'
department:
- _id: KrCh
doi: 10.1016/j.artint.2014.12.009
external_id:
arxiv:
- '1408.2058'
intvolume: ' 221'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1408.2058
month: '04'
oa: 1
oa_version: Preprint
page: 46 - 72
publication: Artificial Intelligence
publication_status: published
publisher: Elsevier
publist_id: '5224'
quality_controlled: '1'
scopus_import: 1
status: public
title: POMDPs under probabilistic semantics
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 221
year: '2015'
...
---
_id: '1879'
abstract:
- lang: eng
text: When electron microscopy (EM) was introduced in the 1930s it gave scientists
their first look into the nanoworld of cells. Over the last 80 years EM has vastly
increased our understanding of the complex cellular structures that underlie the
diverse functions that cells need to maintain life. One drawback that has been
difficult to overcome was the inherent lack of volume information, mainly due
to the limit on the thickness of sections that could be viewed in a transmission
electron microscope (TEM). For many years scientists struggled to achieve three-dimensional
(3D) EM using serial section reconstructions, TEM tomography, and scanning EM
(SEM) techniques such as freeze-fracture. Although each technique yielded some
special information, they required a significant amount of time and specialist
expertise to obtain even a very small 3D EM dataset. Almost 20 years ago scientists
began to exploit SEMs to image blocks of embedded tissues and perform serial sectioning
of these tissues inside the SEM chamber. Using first focused ion beams (FIB) and
subsequently robotic ultramicrotomes (serial block-face, SBF-SEM) microscopists
were able to collect large volumes of 3D EM information at resolutions that could
address many important biological questions, and do so in an efficient manner.
We present here some examples of 3D EM taken from the many diverse specimens that
have been imaged in our core facility. We propose that the next major step forward
will be to efficiently correlate functional information obtained using light microscopy
(LM) with 3D EM datasets to more completely investigate the important links between
cell structures and their functions.
acknowledgement: The Zeiss Merlin with Gatan 3View2XP and Zeiss Auriga were acquired
through a CLEM grant from Minister Ingrid Lieten to the VIB Bio-Imaging-Core. Michiel
Krols and Saskia Lippens are the recipients of a fellowship from the FWO (Fonds
Wetenschappelijk Onderzoek) of Flanders.
author:
- first_name: A
full_name: Kremer, A
last_name: Kremer
- first_name: Stefaan
full_name: Lippens, Stefaan
last_name: Lippens
- first_name: Sonia
full_name: Bartunkova, Sonia
last_name: Bartunkova
- first_name: Bob
full_name: Asselbergh, Bob
last_name: Asselbergh
- first_name: Cendric
full_name: Blanpain, Cendric
last_name: Blanpain
- first_name: Matyas
full_name: Fendrych, Matyas
id: 43905548-F248-11E8-B48F-1D18A9856A87
last_name: Fendrych
orcid: 0000-0002-9767-8699
- first_name: A
full_name: Goossens, A
last_name: Goossens
- first_name: Matthew
full_name: Holt, Matthew
last_name: Holt
- first_name: Sophie
full_name: Janssens, Sophie
last_name: Janssens
- first_name: Michiel
full_name: Krols, Michiel
last_name: Krols
- first_name: Jean
full_name: Larsimont, Jean
last_name: Larsimont
- first_name: Conor
full_name: Mc Guire, Conor
last_name: Mc Guire
- first_name: Moritz
full_name: Nowack, Moritz
last_name: Nowack
- first_name: Xavier
full_name: Saelens, Xavier
last_name: Saelens
- first_name: Andreas
full_name: Schertel, Andreas
last_name: Schertel
- first_name: B
full_name: Schepens, B
last_name: Schepens
- first_name: M
full_name: Slezak, M
last_name: Slezak
- first_name: Vincent
full_name: Timmerman, Vincent
last_name: Timmerman
- first_name: Clara
full_name: Theunis, Clara
last_name: Theunis
- first_name: Ronald
full_name: Van Brempt, Ronald
last_name: Van Brempt
- first_name: Y
full_name: Visser, Y
last_name: Visser
- first_name: Christophe
full_name: Guérin, Christophe
last_name: Guérin
citation:
ama: Kremer A, Lippens S, Bartunkova S, et al. Developing 3D SEM in a broad biological
context. Journal of Microscopy. 2015;259(2):80-96. doi:10.1111/jmi.12211
apa: Kremer, A., Lippens, S., Bartunkova, S., Asselbergh, B., Blanpain, C., Fendrych,
M., … Guérin, C. (2015). Developing 3D SEM in a broad biological context. Journal
of Microscopy. Wiley-Blackwell. https://doi.org/10.1111/jmi.12211
chicago: Kremer, A, Stefaan Lippens, Sonia Bartunkova, Bob Asselbergh, Cendric Blanpain,
Matyas Fendrych, A Goossens, et al. “Developing 3D SEM in a Broad Biological Context.”
Journal of Microscopy. Wiley-Blackwell, 2015. https://doi.org/10.1111/jmi.12211.
ieee: A. Kremer et al., “Developing 3D SEM in a broad biological context,”
Journal of Microscopy, vol. 259, no. 2. Wiley-Blackwell, pp. 80–96, 2015.
ista: Kremer A, Lippens S, Bartunkova S, Asselbergh B, Blanpain C, Fendrych M, Goossens
A, Holt M, Janssens S, Krols M, Larsimont J, Mc Guire C, Nowack M, Saelens X,
Schertel A, Schepens B, Slezak M, Timmerman V, Theunis C, Van Brempt R, Visser
Y, Guérin C. 2015. Developing 3D SEM in a broad biological context. Journal of
Microscopy. 259(2), 80–96.
mla: Kremer, A., et al. “Developing 3D SEM in a Broad Biological Context.” Journal
of Microscopy, vol. 259, no. 2, Wiley-Blackwell, 2015, pp. 80–96, doi:10.1111/jmi.12211.
short: A. Kremer, S. Lippens, S. Bartunkova, B. Asselbergh, C. Blanpain, M. Fendrych,
A. Goossens, M. Holt, S. Janssens, M. Krols, J. Larsimont, C. Mc Guire, M. Nowack,
X. Saelens, A. Schertel, B. Schepens, M. Slezak, V. Timmerman, C. Theunis, R.
Van Brempt, Y. Visser, C. Guérin, Journal of Microscopy 259 (2015) 80–96.
date_created: 2018-12-11T11:54:30Z
date_published: 2015-08-01T00:00:00Z
date_updated: 2021-01-12T06:53:48Z
day: '01'
ddc:
- '570'
department:
- _id: JiFr
doi: 10.1111/jmi.12211
file:
- access_level: open_access
checksum: 3649c5372d1644062d728ea9287e367f
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:11:19Z
date_updated: 2020-07-14T12:45:19Z
file_id: '4872'
file_name: IST-2016-459-v1+1_KREMER_et_al-2015-Journal_of_Microscopy.pdf
file_size: 2899898
relation: main_file
file_date_updated: 2020-07-14T12:45:19Z
has_accepted_license: '1'
intvolume: ' 259'
issue: '2'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 80 - 96
publication: Journal of Microscopy
publication_status: published
publisher: Wiley-Blackwell
publist_id: '5218'
pubrep_id: '459'
quality_controlled: '1'
scopus_import: 1
status: public
title: Developing 3D SEM in a broad biological context
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 259
year: '2015'
...
---
_id: '1880'
abstract:
- lang: eng
text: We investigate the relation between Bose-Einstein condensation (BEC) and superfluidity
in the ground state of a one-dimensional model of interacting bosons in a strong
random potential. We prove rigorously that in a certain parameter regime the superfluid
fraction can be arbitrarily small while complete BEC prevails. In another regime
there is both complete BEC and complete superfluidity, despite the strong disorder
acknowledgement: Support from the Natural Sciences and Engineering Research Council
of Canada NSERC (MK and RS) and from the Austrian Science Fund FWF (JY, under project
P 22929-N16) is gratefully acknowledged
article_number: '013022'
author:
- first_name: Martin
full_name: Könenberg, Martin
last_name: Könenberg
- first_name: Thomas
full_name: Moser, Thomas
id: 2B5FC9A4-F248-11E8-B48F-1D18A9856A87
last_name: Moser
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
- first_name: Jakob
full_name: Yngvason, Jakob
last_name: Yngvason
citation:
ama: Könenberg M, Moser T, Seiringer R, Yngvason J. Superfluid behavior of a Bose-Einstein
condensate in a random potential. New Journal of Physics. 2015;17. doi:10.1088/1367-2630/17/1/013022
apa: Könenberg, M., Moser, T., Seiringer, R., & Yngvason, J. (2015). Superfluid
behavior of a Bose-Einstein condensate in a random potential. New Journal of
Physics. IOP Publishing Ltd. https://doi.org/10.1088/1367-2630/17/1/013022
chicago: Könenberg, Martin, Thomas Moser, Robert Seiringer, and Jakob Yngvason.
“Superfluid Behavior of a Bose-Einstein Condensate in a Random Potential.” New
Journal of Physics. IOP Publishing Ltd., 2015. https://doi.org/10.1088/1367-2630/17/1/013022.
ieee: M. Könenberg, T. Moser, R. Seiringer, and J. Yngvason, “Superfluid behavior
of a Bose-Einstein condensate in a random potential,” New Journal of Physics,
vol. 17. IOP Publishing Ltd., 2015.
ista: Könenberg M, Moser T, Seiringer R, Yngvason J. 2015. Superfluid behavior of
a Bose-Einstein condensate in a random potential. New Journal of Physics. 17,
013022.
mla: Könenberg, Martin, et al. “Superfluid Behavior of a Bose-Einstein Condensate
in a Random Potential.” New Journal of Physics, vol. 17, 013022, IOP Publishing
Ltd., 2015, doi:10.1088/1367-2630/17/1/013022.
short: M. Könenberg, T. Moser, R. Seiringer, J. Yngvason, New Journal of Physics
17 (2015).
date_created: 2018-12-11T11:54:30Z
date_published: 2015-01-15T00:00:00Z
date_updated: 2021-01-12T06:53:48Z
day: '15'
ddc:
- '530'
department:
- _id: RoSe
doi: 10.1088/1367-2630/17/1/013022
file:
- access_level: open_access
checksum: 38fdf2b5ac30445e26a5d613abd84b16
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:12:44Z
date_updated: 2020-07-14T12:45:20Z
file_id: '4963'
file_name: IST-2016-447-v1+1_document_1_.pdf
file_size: 768108
relation: main_file
file_date_updated: 2020-07-14T12:45:20Z
has_accepted_license: '1'
intvolume: ' 17'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
project:
- _id: 26450934-B435-11E9-9278-68D0E5697425
name: NSERC Postdoctoral fellowship
publication: New Journal of Physics
publication_status: published
publisher: IOP Publishing Ltd.
publist_id: '5214'
pubrep_id: '447'
quality_controlled: '1'
scopus_import: 1
status: public
title: Superfluid behavior of a Bose-Einstein condensate in a random potential
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2015'
...
---
_id: '1882'
abstract:
- lang: eng
text: We provide a framework for compositional and iterative design and verification
of systems with quantitative information, such as rewards, time or energy. It
is based on disjunctive modal transition systems where we allow actions to bear
various types of quantitative information. Throughout the design process the actions
can be further refined and the information made more precise. We show how to compute
the results of standard operations on the systems, including the quotient (residual),
which has not been previously considered for quantitative non-deterministic systems.
Our quantitative framework has close connections to the modal nu-calculus and
is compositional with respect to general notions of distances between systems
and the standard operations.
acknowledgement: This research was funded in part by the European Research Council
(ERC) under grant agreement 267989 (QUAREM), by the Austrian Science Fund (FWF)
project S11402-N23 (RiSE), and by the Czech Science Foundation, grant No. P202/12/G061.
alternative_title:
- LNCS
author:
- first_name: Uli
full_name: Fahrenberg, Uli
last_name: Fahrenberg
- first_name: Jan
full_name: Kretinsky, Jan
id: 44CEF464-F248-11E8-B48F-1D18A9856A87
last_name: Kretinsky
orcid: 0000-0002-8122-2881
- first_name: Axel
full_name: Legay, Axel
last_name: Legay
- first_name: Louis
full_name: Traonouez, Louis
last_name: Traonouez
citation:
ama: 'Fahrenberg U, Kretinsky J, Legay A, Traonouez L. Compositionality for quantitative
specifications. In: Vol 8997. Springer; 2015:306-324. doi:10.1007/978-3-319-15317-9_19'
apa: 'Fahrenberg, U., Kretinsky, J., Legay, A., & Traonouez, L. (2015). Compositionality
for quantitative specifications (Vol. 8997, pp. 306–324). Presented at the FACS:
Formal Aspects of Component Software, Bertinoro, Italy: Springer. https://doi.org/10.1007/978-3-319-15317-9_19'
chicago: Fahrenberg, Uli, Jan Kretinsky, Axel Legay, and Louis Traonouez. “Compositionality
for Quantitative Specifications,” 8997:306–24. Springer, 2015. https://doi.org/10.1007/978-3-319-15317-9_19.
ieee: 'U. Fahrenberg, J. Kretinsky, A. Legay, and L. Traonouez, “Compositionality
for quantitative specifications,” presented at the FACS: Formal Aspects of Component
Software, Bertinoro, Italy, 2015, vol. 8997, pp. 306–324.'
ista: 'Fahrenberg U, Kretinsky J, Legay A, Traonouez L. 2015. Compositionality for
quantitative specifications. FACS: Formal Aspects of Component Software, LNCS,
vol. 8997, 306–324.'
mla: Fahrenberg, Uli, et al. Compositionality for Quantitative Specifications.
Vol. 8997, Springer, 2015, pp. 306–24, doi:10.1007/978-3-319-15317-9_19.
short: U. Fahrenberg, J. Kretinsky, A. Legay, L. Traonouez, in:, Springer, 2015,
pp. 306–324.
conference:
end_date: 2014-09-12
location: Bertinoro, Italy
name: 'FACS: Formal Aspects of Component Software'
start_date: 2014-09-10
date_created: 2018-12-11T11:54:31Z
date_published: 2015-01-30T00:00:00Z
date_updated: 2021-01-12T06:53:49Z
day: '30'
department:
- _id: ToHe
- _id: KrCh
doi: 10.1007/978-3-319-15317-9_19
ec_funded: 1
intvolume: ' 8997'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1408.1256
month: '01'
oa: 1
oa_version: Preprint
page: 306 - 324
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
publication_status: published
publisher: Springer
publist_id: '5216'
quality_controlled: '1'
scopus_import: 1
status: public
title: Compositionality for quantitative specifications
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8997
year: '2015'
...
---
_id: '1883'
abstract:
- lang: eng
text: "We introduce a one-parametric family of tree growth models, in which branching
probabilities decrease with branch age τ as τ-α. Depending on the exponent α,
the scaling of tree depth with tree size n displays a transition between the logarithmic
scaling of random trees and an algebraic growth. At the transition (α=1) tree
depth grows as (logn)2. This anomalous scaling is in good agreement with the trend
observed in evolution of biological species, thus providing a theoretical support
for age-dependent speciation and associating it to the occurrence of a critical
point.\r\n"
article_number: '022803'
article_processing_charge: No
article_type: original
author:
- first_name: Stephanie
full_name: Keller-Schmidt, Stephanie
last_name: Keller-Schmidt
- first_name: Murat
full_name: Tugrul, Murat
id: 37C323C6-F248-11E8-B48F-1D18A9856A87
last_name: Tugrul
orcid: 0000-0002-8523-0758
- first_name: Víctor
full_name: Eguíluz, Víctor
last_name: Eguíluz
- first_name: Emilio
full_name: Hernandez Garcia, Emilio
last_name: Hernandez Garcia
- first_name: Konstantin
full_name: Klemm, Konstantin
last_name: Klemm
citation:
ama: Keller-Schmidt S, Tugrul M, Eguíluz V, Hernandez Garcia E, Klemm K. Anomalous
scaling in an age-dependent branching model. Physical Review E Statistical
Nonlinear and Soft Matter Physics. 2015;91(2). doi:10.1103/PhysRevE.91.022803
apa: Keller-Schmidt, S., Tugrul, M., Eguíluz, V., Hernandez Garcia, E., & Klemm,
K. (2015). Anomalous scaling in an age-dependent branching model. Physical
Review E Statistical Nonlinear and Soft Matter Physics. American Institute
of Physics. https://doi.org/10.1103/PhysRevE.91.022803
chicago: Keller-Schmidt, Stephanie, Murat Tugrul, Víctor Eguíluz, Emilio Hernandez
Garcia, and Konstantin Klemm. “Anomalous Scaling in an Age-Dependent Branching
Model.” Physical Review E Statistical Nonlinear and Soft Matter Physics.
American Institute of Physics, 2015. https://doi.org/10.1103/PhysRevE.91.022803.
ieee: S. Keller-Schmidt, M. Tugrul, V. Eguíluz, E. Hernandez Garcia, and K. Klemm,
“Anomalous scaling in an age-dependent branching model,” Physical Review E
Statistical Nonlinear and Soft Matter Physics, vol. 91, no. 2. American Institute
of Physics, 2015.
ista: Keller-Schmidt S, Tugrul M, Eguíluz V, Hernandez Garcia E, Klemm K. 2015.
Anomalous scaling in an age-dependent branching model. Physical Review E Statistical
Nonlinear and Soft Matter Physics. 91(2), 022803.
mla: Keller-Schmidt, Stephanie, et al. “Anomalous Scaling in an Age-Dependent Branching
Model.” Physical Review E Statistical Nonlinear and Soft Matter Physics,
vol. 91, no. 2, 022803, American Institute of Physics, 2015, doi:10.1103/PhysRevE.91.022803.
short: S. Keller-Schmidt, M. Tugrul, V. Eguíluz, E. Hernandez Garcia, K. Klemm,
Physical Review E Statistical Nonlinear and Soft Matter Physics 91 (2015).
date_created: 2018-12-11T11:54:31Z
date_published: 2015-02-02T00:00:00Z
date_updated: 2021-01-12T06:53:49Z
day: '02'
department:
- _id: NiBa
doi: 10.1103/PhysRevE.91.022803
external_id:
arxiv:
- '1012.3298'
intvolume: ' 91'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1012.3298
month: '02'
oa: 1
oa_version: Preprint
publication: Physical Review E Statistical Nonlinear and Soft Matter Physics
publication_status: published
publisher: American Institute of Physics
publist_id: '5213'
quality_controlled: '1'
scopus_import: 1
status: public
title: Anomalous scaling in an age-dependent branching model
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 91
year: '2015'
...
---
_id: '1878'
abstract:
- lang: eng
text: Petrocoptis is a small genus of chasmophytic plants endemic to the Iberian
Peninsula, with some localized populations in the French Pyrenees. Within the
genus, a dozen species have been recognized based on morphological diversity,
most of them with limited distribution area, in small populations and frequently
with potential threats to their survival. To date, however, a molecular evaluation
of the current systematic treatments has not been carried out. The aim of the
present study is to infer phylogenetic relationships among its subordinate taxa
by using plastidial rps16 intron and nuclear internal transcribed spacer (ITS)
DNA sequences; and evaluate the phylogenetic placement of the genus Petrocoptis
within the family Caryophyllaceae. The monophyly of Petrocoptis is supported by
both ITS and rps16 intron sequence analyses. Furthermore, time estimates using
BEAST analyses indicate a Middle to Late Miocene diversification (10.59 Myr, 6.44–15.26
Myr highest posterior densities [HPD], for ITS; 14.30 Myr, 8.61–21.00 Myr HPD,
for rps16 intron).
author:
- first_name: Eduardo
full_name: Cires Rodriguez, Eduardo
id: 2AD56A7A-F248-11E8-B48F-1D18A9856A87
last_name: Cires Rodriguez
- first_name: José
full_name: Prieto, José
last_name: Prieto
citation:
ama: Cires Rodriguez E, Prieto J. Phylogenetic relationships of Petrocoptis A. Braun
ex Endl. (Caryophyllaceae), a discussed genus from the Iberian Peninsula. Journal
of Plant Research. 2015;128(2):223-238. doi:10.1007/s10265-014-0691-6
apa: Cires Rodriguez, E., & Prieto, J. (2015). Phylogenetic relationships of
Petrocoptis A. Braun ex Endl. (Caryophyllaceae), a discussed genus from the Iberian
Peninsula. Journal of Plant Research. Springer. https://doi.org/10.1007/s10265-014-0691-6
chicago: Cires Rodriguez, Eduardo, and José Prieto. “Phylogenetic Relationships
of Petrocoptis A. Braun Ex Endl. (Caryophyllaceae), a Discussed Genus from the
Iberian Peninsula.” Journal of Plant Research. Springer, 2015. https://doi.org/10.1007/s10265-014-0691-6.
ieee: E. Cires Rodriguez and J. Prieto, “Phylogenetic relationships of Petrocoptis
A. Braun ex Endl. (Caryophyllaceae), a discussed genus from the Iberian Peninsula,”
Journal of Plant Research, vol. 128, no. 2. Springer, pp. 223–238, 2015.
ista: Cires Rodriguez E, Prieto J. 2015. Phylogenetic relationships of Petrocoptis
A. Braun ex Endl. (Caryophyllaceae), a discussed genus from the Iberian Peninsula.
Journal of Plant Research. 128(2), 223–238.
mla: Cires Rodriguez, Eduardo, and José Prieto. “Phylogenetic Relationships of Petrocoptis
A. Braun Ex Endl. (Caryophyllaceae), a Discussed Genus from the Iberian Peninsula.”
Journal of Plant Research, vol. 128, no. 2, Springer, 2015, pp. 223–38,
doi:10.1007/s10265-014-0691-6.
short: E. Cires Rodriguez, J. Prieto, Journal of Plant Research 128 (2015) 223–238.
date_created: 2018-12-11T11:54:30Z
date_published: 2015-01-24T00:00:00Z
date_updated: 2021-01-12T06:53:47Z
day: '24'
department:
- _id: JiFr
doi: 10.1007/s10265-014-0691-6
intvolume: ' 128'
issue: '2'
language:
- iso: eng
month: '01'
oa_version: None
page: 223 - 238
publication: Journal of Plant Research
publication_status: published
publisher: Springer
publist_id: '5217'
quality_controlled: '1'
scopus_import: 1
status: public
title: Phylogenetic relationships of Petrocoptis A. Braun ex Endl. (Caryophyllaceae),
a discussed genus from the Iberian Peninsula
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 128
year: '2015'
...
---
_id: '1885'
abstract:
- lang: eng
text: 'The concept of positional information is central to our understanding of
how cells determine their location in a multicellular structure and thereby their
developmental fates. Nevertheless, positional information has neither been defined
mathematically nor quantified in a principled way. Here we provide an information-theoretic
definition in the context of developmental gene expression patterns and examine
the features of expression patterns that affect positional information quantitatively.
We connect positional information with the concept of positional error and develop
tools to directly measure information and error from experimental data. We illustrate
our framework for the case of gap gene expression patterns in the early Drosophila
embryo and show how information that is distributed among only four genes is sufficient
to determine developmental fates with nearly single-cell resolution. Our approach
can be generalized to a variety of different model systems; procedures and examples
are discussed in detail. '
author:
- first_name: Gasper
full_name: Tkacik, Gasper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkacik
orcid: 0000-0002-6699-1455
- first_name: Julien
full_name: Dubuis, Julien
last_name: Dubuis
- first_name: Mariela
full_name: Petkova, Mariela
last_name: Petkova
- first_name: Thomas
full_name: Gregor, Thomas
last_name: Gregor
citation:
ama: 'Tkačik G, Dubuis J, Petkova M, Gregor T. Positional information, positional
error, and readout precision in morphogenesis: A mathematical framework. Genetics.
2015;199(1):39-59. doi:10.1534/genetics.114.171850'
apa: 'Tkačik, G., Dubuis, J., Petkova, M., & Gregor, T. (2015). Positional information,
positional error, and readout precision in morphogenesis: A mathematical framework.
Genetics. Genetics Society of America. https://doi.org/10.1534/genetics.114.171850'
chicago: 'Tkačik, Gašper, Julien Dubuis, Mariela Petkova, and Thomas Gregor. “Positional
Information, Positional Error, and Readout Precision in Morphogenesis: A Mathematical
Framework.” Genetics. Genetics Society of America, 2015. https://doi.org/10.1534/genetics.114.171850.'
ieee: 'G. Tkačik, J. Dubuis, M. Petkova, and T. Gregor, “Positional information,
positional error, and readout precision in morphogenesis: A mathematical framework,”
Genetics, vol. 199, no. 1. Genetics Society of America, pp. 39–59, 2015.'
ista: 'Tkačik G, Dubuis J, Petkova M, Gregor T. 2015. Positional information, positional
error, and readout precision in morphogenesis: A mathematical framework. Genetics.
199(1), 39–59.'
mla: 'Tkačik, Gašper, et al. “Positional Information, Positional Error, and Readout
Precision in Morphogenesis: A Mathematical Framework.” Genetics, vol. 199,
no. 1, Genetics Society of America, 2015, pp. 39–59, doi:10.1534/genetics.114.171850.'
short: G. Tkačik, J. Dubuis, M. Petkova, T. Gregor, Genetics 199 (2015) 39–59.
date_created: 2018-12-11T11:54:32Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2021-01-12T06:53:50Z
day: '01'
department:
- _id: GaTk
doi: 10.1534/genetics.114.171850
intvolume: ' 199'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1404.5599
month: '01'
oa: 1
oa_version: Preprint
page: 39 - 59
publication: Genetics
publication_status: published
publisher: Genetics Society of America
publist_id: '5210'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Positional information, positional error, and readout precision in morphogenesis:
A mathematical framework'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 199
year: '2015'
...
---
_id: '1940'
abstract:
- lang: eng
text: We typically think of cells as responding to external signals independently
by regulating their gene expression levels, yet they often locally exchange information
and coordinate. Can such spatial coupling be of benefit for conveying signals
subject to gene regulatory noise? Here we extend our information-theoretic framework
for gene regulation to spatially extended systems. As an example, we consider
a lattice of nuclei responding to a concentration field of a transcriptional regulator
(the "input") by expressing a single diffusible target gene. When input
concentrations are low, diffusive coupling markedly improves information transmission;
optimal gene activation functions also systematically change. A qualitatively
new regulatory strategy emerges where individual cells respond to the input in
a nearly step-like fashion that is subsequently averaged out by strong diffusion.
While motivated by early patterning events in the Drosophila embryo, our framework
is generically applicable to spatially coupled stochastic gene expression models.
article_number: '062710'
author:
- first_name: Thomas R
full_name: Sokolowski, Thomas R
id: 3E999752-F248-11E8-B48F-1D18A9856A87
last_name: Sokolowski
orcid: 0000-0002-1287-3779
- first_name: Gasper
full_name: Tkacik, Gasper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkacik
orcid: 0000-0002-6699-1455
citation:
ama: Sokolowski TR, Tkačik G. Optimizing information flow in small genetic networks.
IV. Spatial coupling. Physical Review E Statistical Nonlinear and Soft Matter
Physics. 2015;91(6). doi:10.1103/PhysRevE.91.062710
apa: Sokolowski, T. R., & Tkačik, G. (2015). Optimizing information flow in
small genetic networks. IV. Spatial coupling. Physical Review E Statistical
Nonlinear and Soft Matter Physics. American Institute of Physics. https://doi.org/10.1103/PhysRevE.91.062710
chicago: Sokolowski, Thomas R, and Gašper Tkačik. “Optimizing Information Flow in
Small Genetic Networks. IV. Spatial Coupling.” Physical Review E Statistical
Nonlinear and Soft Matter Physics. American Institute of Physics, 2015. https://doi.org/10.1103/PhysRevE.91.062710.
ieee: T. R. Sokolowski and G. Tkačik, “Optimizing information flow in small genetic
networks. IV. Spatial coupling,” Physical Review E Statistical Nonlinear and
Soft Matter Physics, vol. 91, no. 6. American Institute of Physics, 2015.
ista: Sokolowski TR, Tkačik G. 2015. Optimizing information flow in small genetic
networks. IV. Spatial coupling. Physical Review E Statistical Nonlinear and Soft
Matter Physics. 91(6), 062710.
mla: Sokolowski, Thomas R., and Gašper Tkačik. “Optimizing Information Flow in Small
Genetic Networks. IV. Spatial Coupling.” Physical Review E Statistical Nonlinear
and Soft Matter Physics, vol. 91, no. 6, 062710, American Institute of Physics,
2015, doi:10.1103/PhysRevE.91.062710.
short: T.R. Sokolowski, G. Tkačik, Physical Review E Statistical Nonlinear and Soft
Matter Physics 91 (2015).
date_created: 2018-12-11T11:54:49Z
date_published: 2015-06-15T00:00:00Z
date_updated: 2021-01-12T06:54:13Z
day: '15'
department:
- _id: GaTk
doi: 10.1103/PhysRevE.91.062710
intvolume: ' 91'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1501.04015
month: '06'
oa: 1
oa_version: Preprint
publication: Physical Review E Statistical Nonlinear and Soft Matter Physics
publication_status: published
publisher: American Institute of Physics
publist_id: '5145'
quality_controlled: '1'
scopus_import: 1
status: public
title: Optimizing information flow in small genetic networks. IV. Spatial coupling
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 91
year: '2015'
...
---
_id: '1938'
abstract:
- lang: eng
text: 'We numerically investigate the distribution of extrema of ''chaotic'' Laplacian
eigenfunctions on two-dimensional manifolds. Our contribution is two-fold: (a)
we count extrema on grid graphs with a small number of randomly added edges and
show the behavior to coincide with the 1957 prediction of Longuet-Higgins for
the continuous case and (b) we compute the regularity of their spatial distribution
using discrepancy, which is a classical measure from the theory of Monte Carlo
integration. The first part suggests that grid graphs with randomly added edges
should behave like two-dimensional surfaces with ergodic geodesic flow; in the
second part we show that the extrema are more regularly distributed in space than
the grid Z2.'
acknowledgement: "F.P. was supported by the Graduate School of IST Austria. S.S. was
partially supported by CRC1060 of the DFG\r\nThe authors thank Olga Symonova and
Michael Kerber for sharing their implementation of the persistence algorithm. "
author:
- first_name: Florian
full_name: Pausinger, Florian
id: 2A77D7A2-F248-11E8-B48F-1D18A9856A87
last_name: Pausinger
orcid: 0000-0002-8379-3768
- first_name: Stefan
full_name: Steinerberger, Stefan
last_name: Steinerberger
citation:
ama: Pausinger F, Steinerberger S. On the distribution of local extrema in quantum
chaos. Physics Letters, Section A. 2015;379(6):535-541. doi:10.1016/j.physleta.2014.12.010
apa: Pausinger, F., & Steinerberger, S. (2015). On the distribution of local
extrema in quantum chaos. Physics Letters, Section A. Elsevier. https://doi.org/10.1016/j.physleta.2014.12.010
chicago: Pausinger, Florian, and Stefan Steinerberger. “On the Distribution of Local
Extrema in Quantum Chaos.” Physics Letters, Section A. Elsevier, 2015.
https://doi.org/10.1016/j.physleta.2014.12.010.
ieee: F. Pausinger and S. Steinerberger, “On the distribution of local extrema in
quantum chaos,” Physics Letters, Section A, vol. 379, no. 6. Elsevier,
pp. 535–541, 2015.
ista: Pausinger F, Steinerberger S. 2015. On the distribution of local extrema in
quantum chaos. Physics Letters, Section A. 379(6), 535–541.
mla: Pausinger, Florian, and Stefan Steinerberger. “On the Distribution of Local
Extrema in Quantum Chaos.” Physics Letters, Section A, vol. 379, no. 6,
Elsevier, 2015, pp. 535–41, doi:10.1016/j.physleta.2014.12.010.
short: F. Pausinger, S. Steinerberger, Physics Letters, Section A 379 (2015) 535–541.
date_created: 2018-12-11T11:54:49Z
date_published: 2015-03-06T00:00:00Z
date_updated: 2021-01-12T06:54:12Z
day: '06'
department:
- _id: HeEd
doi: 10.1016/j.physleta.2014.12.010
intvolume: ' 379'
issue: '6'
language:
- iso: eng
month: '03'
oa_version: None
page: 535 - 541
publication: Physics Letters, Section A
publication_status: published
publisher: Elsevier
publist_id: '5152'
quality_controlled: '1'
scopus_import: 1
status: public
title: On the distribution of local extrema in quantum chaos
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 379
year: '2015'
...
---
_id: '1944'
acknowledgement: This work was supported by the European Research Council (project
ERC-2011-StG-20101109-PSDP); the Agency for Innovation by Science and Technology
(IWT) (predoctoral fellowship to H.R.); and the People Programme (Marie Curie Actions)
of the European Union
author:
- first_name: Hana
full_name: Rakusová, Hana
last_name: Rakusová
- first_name: Matyas
full_name: Fendrych, Matyas
id: 43905548-F248-11E8-B48F-1D18A9856A87
last_name: Fendrych
orcid: 0000-0002-9767-8699
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Rakusová H, Fendrych M, Friml J. Intracellular trafficking and PIN-mediated
cell polarity during tropic responses in plants. Current Opinion in Plant Biology.
2015;23(2):116-123. doi:10.1016/j.pbi.2014.12.002
apa: Rakusová, H., Fendrych, M., & Friml, J. (2015). Intracellular trafficking
and PIN-mediated cell polarity during tropic responses in plants. Current Opinion
in Plant Biology. Elsevier. https://doi.org/10.1016/j.pbi.2014.12.002
chicago: Rakusová, Hana, Matyas Fendrych, and Jiří Friml. “Intracellular Trafficking
and PIN-Mediated Cell Polarity during Tropic Responses in Plants.” Current
Opinion in Plant Biology. Elsevier, 2015. https://doi.org/10.1016/j.pbi.2014.12.002.
ieee: H. Rakusová, M. Fendrych, and J. Friml, “Intracellular trafficking and PIN-mediated
cell polarity during tropic responses in plants,” Current Opinion in Plant
Biology, vol. 23, no. 2. Elsevier, pp. 116–123, 2015.
ista: Rakusová H, Fendrych M, Friml J. 2015. Intracellular trafficking and PIN-mediated
cell polarity during tropic responses in plants. Current Opinion in Plant Biology.
23(2), 116–123.
mla: Rakusová, Hana, et al. “Intracellular Trafficking and PIN-Mediated Cell Polarity
during Tropic Responses in Plants.” Current Opinion in Plant Biology, vol.
23, no. 2, Elsevier, 2015, pp. 116–23, doi:10.1016/j.pbi.2014.12.002.
short: H. Rakusová, M. Fendrych, J. Friml, Current Opinion in Plant Biology 23 (2015)
116–123.
date_created: 2018-12-11T11:54:51Z
date_published: 2015-02-01T00:00:00Z
date_updated: 2021-01-12T06:54:15Z
day: '01'
department:
- _id: JiFr
doi: 10.1016/j.pbi.2014.12.002
ec_funded: 1
intvolume: ' 23'
issue: '2'
language:
- iso: eng
month: '02'
oa_version: None
page: 116 - 123
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '282300'
name: Polarity and subcellular dynamics in plants
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Current Opinion in Plant Biology
publication_status: published
publisher: Elsevier
publist_id: '5140'
quality_controlled: '1'
scopus_import: 1
status: public
title: Intracellular trafficking and PIN-mediated cell polarity during tropic responses
in plants
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 23
year: '2015'
...
---
_id: '1992'
abstract:
- lang: eng
text: "We present a method and a tool for generating succinct representations of
sets of concurrent traces. We focus on trace sets that contain all correct or
all incorrect permutations of events from a given trace. We represent trace sets
as HB-Formulas that are Boolean combinations of happens-before constraints between
events. To generate a representation of incorrect interleavings, our method iteratively
explores interleavings that violate the specification and gathers generalizations
of the discovered interleavings into an HB-Formula; its complement yields a representation
of correct interleavings.\r\n\r\nWe claim that our trace set representations can
drive diverse verification, fault localization, repair, and synthesis techniques
for concurrent programs. We demonstrate this by using our tool in three case studies
involving synchronization synthesis, bug summarization, and abstraction refinement
based verification. In each case study, our initial experimental results have
been promising.\r\n\r\nIn the first case study, we present an algorithm for inferring
missing synchronization from an HB-Formula representing correct interleavings
of a given trace. The algorithm applies rules to rewrite specific patterns in
the HB-Formula into locks, barriers, and wait-notify constructs. In the second
case study, we use an HB-Formula representing incorrect interleavings for bug
summarization. While the HB-Formula itself is a concise counterexample summary,
we present additional inference rules to help identify specific concurrency bugs
such as data races, define-use order violations, and two-stage access bugs. In
the final case study, we present a novel predicate learning procedure that uses
HB-Formulas representing abstract counterexamples to accelerate counterexample-guided
abstraction refinement (CEGAR). In each iteration of the CEGAR loop, the procedure
refines the abstraction to eliminate multiple spurious abstract counterexamples
drawn from the HB-Formula."
author:
- first_name: Ashutosh
full_name: Gupta, Ashutosh
id: 335E5684-F248-11E8-B48F-1D18A9856A87
last_name: Gupta
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Arjun
full_name: Radhakrishna, Arjun
id: 3B51CAC4-F248-11E8-B48F-1D18A9856A87
last_name: Radhakrishna
- first_name: Roopsha
full_name: Samanta, Roopsha
id: 3D2AAC08-F248-11E8-B48F-1D18A9856A87
last_name: Samanta
- first_name: Thorsten
full_name: Tarrach, Thorsten
id: 3D6E8F2C-F248-11E8-B48F-1D18A9856A87
last_name: Tarrach
orcid: 0000-0003-4409-8487
citation:
ama: 'Gupta A, Henzinger TA, Radhakrishna A, Samanta R, Tarrach T. Succinct representation
of concurrent trace sets. In: ACM; 2015:433-444. doi:10.1145/2676726.2677008'
apa: 'Gupta, A., Henzinger, T. A., Radhakrishna, A., Samanta, R., & Tarrach,
T. (2015). Succinct representation of concurrent trace sets (pp. 433–444). Presented
at the POPL: Principles of Programming Languages, Mumbai, India: ACM. https://doi.org/10.1145/2676726.2677008'
chicago: Gupta, Ashutosh, Thomas A Henzinger, Arjun Radhakrishna, Roopsha Samanta,
and Thorsten Tarrach. “Succinct Representation of Concurrent Trace Sets,” 433–44.
ACM, 2015. https://doi.org/10.1145/2676726.2677008.
ieee: 'A. Gupta, T. A. Henzinger, A. Radhakrishna, R. Samanta, and T. Tarrach, “Succinct
representation of concurrent trace sets,” presented at the POPL: Principles of
Programming Languages, Mumbai, India, 2015, pp. 433–444.'
ista: 'Gupta A, Henzinger TA, Radhakrishna A, Samanta R, Tarrach T. 2015. Succinct
representation of concurrent trace sets. POPL: Principles of Programming Languages,
433–444.'
mla: Gupta, Ashutosh, et al. Succinct Representation of Concurrent Trace Sets.
ACM, 2015, pp. 433–44, doi:10.1145/2676726.2677008.
short: A. Gupta, T.A. Henzinger, A. Radhakrishna, R. Samanta, T. Tarrach, in:, ACM,
2015, pp. 433–444.
conference:
end_date: 2015-01-17
location: Mumbai, India
name: 'POPL: Principles of Programming Languages'
start_date: 2015-01-15
date_created: 2018-12-11T11:55:05Z
date_published: 2015-01-15T00:00:00Z
date_updated: 2021-01-12T06:54:33Z
day: '15'
ddc:
- '005'
department:
- _id: ToHe
doi: 10.1145/2676726.2677008
file:
- access_level: open_access
checksum: f0d4395b600f410a191256ac0b73af32
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:17:56Z
date_updated: 2020-07-14T12:45:22Z
file_id: '5314'
file_name: IST-2015-317-v1+1_author_version.pdf
file_size: 399462
relation: main_file
file_date_updated: 2020-07-14T12:45:22Z
has_accepted_license: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Submitted Version
page: 433 - 444
publication_identifier:
isbn:
- 978-1-4503-3300-9
publication_status: published
publisher: ACM
publist_id: '5091'
pubrep_id: '317'
quality_controlled: '1'
scopus_import: 1
status: public
title: Succinct representation of concurrent trace sets
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '1997'
abstract:
- lang: eng
text: We prove that the three-state toric homogeneous Markov chain model has Markov
degree two. In algebraic terminology this means, that a certain class of toric
ideals is generated by quadratic binomials. This was conjectured by Haws, Martin
del Campo, Takemura and Yoshida, who proved that they are generated by degree
six binomials.
author:
- first_name: Patrik
full_name: Noren, Patrik
id: 46870C74-F248-11E8-B48F-1D18A9856A87
last_name: Noren
citation:
ama: Noren P. The three-state toric homogeneous Markov chain model has Markov degree
two. Journal of Symbolic Computation. 2015;68/Part 2(May-June):285-296.
doi:10.1016/j.jsc.2014.09.014
apa: Noren, P. (2015). The three-state toric homogeneous Markov chain model has
Markov degree two. Journal of Symbolic Computation. Elsevier. https://doi.org/10.1016/j.jsc.2014.09.014
chicago: Noren, Patrik. “The Three-State Toric Homogeneous Markov Chain Model Has
Markov Degree Two.” Journal of Symbolic Computation. Elsevier, 2015. https://doi.org/10.1016/j.jsc.2014.09.014.
ieee: P. Noren, “The three-state toric homogeneous Markov chain model has Markov
degree two,” Journal of Symbolic Computation, vol. 68/Part 2, no. May-June.
Elsevier, pp. 285–296, 2015.
ista: Noren P. 2015. The three-state toric homogeneous Markov chain model has Markov
degree two. Journal of Symbolic Computation. 68/Part 2(May-June), 285–296.
mla: Noren, Patrik. “The Three-State Toric Homogeneous Markov Chain Model Has Markov
Degree Two.” Journal of Symbolic Computation, vol. 68/Part 2, no. May-June,
Elsevier, 2015, pp. 285–96, doi:10.1016/j.jsc.2014.09.014.
short: P. Noren, Journal of Symbolic Computation 68/Part 2 (2015) 285–296.
date_created: 2018-12-11T11:55:07Z
date_published: 2015-05-01T00:00:00Z
date_updated: 2021-01-12T06:54:35Z
day: '01'
department:
- _id: CaUh
doi: 10.1016/j.jsc.2014.09.014
issue: May-June
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1207.0077
month: '05'
oa: 1
oa_version: Preprint
page: 285 - 296
publication: Journal of Symbolic Computation
publication_status: published
publisher: Elsevier
publist_id: '5082'
quality_controlled: '1'
scopus_import: 1
status: public
title: The three-state toric homogeneous Markov chain model has Markov degree two
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 68/Part 2
year: '2015'
...
---
_id: '2008'
abstract:
- lang: eng
text: The paper describes a generalized iterative proportional fitting procedure
that can be used for maximum likelihood estimation in a special class of the general
log-linear model. The models in this class, called relational, apply to multivariate
discrete sample spaces that do not necessarily have a Cartesian product structure
and may not contain an overall effect. When applied to the cell probabilities,
the models without the overall effect are curved exponential families and the
values of the sufficient statistics are reproduced by the MLE only up to a constant
of proportionality. The paper shows that Iterative Proportional Fitting, Generalized
Iterative Scaling, and Improved Iterative Scaling fail to work for such models.
The algorithm proposed here is based on iterated Bregman projections. As a by-product,
estimates of the multiplicative parameters are also obtained. An implementation
of the algorithm is available as an R-package.
acknowledgement: Part of the material presented here was contained in the PhD thesis
of the first author to which the second author and Thomas Richardson were advisers.
The authors wish to thank him for several comments and suggestions. We also thank
the reviewers and the Associate Editor for helpful comments. The proof of Proposition 1
uses the idea of Olga Klimova, to whom the authors are also indebted. The second
author was supported in part by Grant K-106154 from the Hungarian National Scientific
Research Fund (OTKA).
author:
- first_name: Anna
full_name: Klimova, Anna
id: 31934120-F248-11E8-B48F-1D18A9856A87
last_name: Klimova
- first_name: Tamás
full_name: Rudas, Tamás
last_name: Rudas
citation:
ama: Klimova A, Rudas T. Iterative scaling in curved exponential families. Scandinavian
Journal of Statistics. 2015;42(3):832-847. doi:10.1111/sjos.12139
apa: Klimova, A., & Rudas, T. (2015). Iterative scaling in curved exponential
families. Scandinavian Journal of Statistics. Wiley. https://doi.org/10.1111/sjos.12139
chicago: Klimova, Anna, and Tamás Rudas. “Iterative Scaling in Curved Exponential
Families.” Scandinavian Journal of Statistics. Wiley, 2015. https://doi.org/10.1111/sjos.12139.
ieee: A. Klimova and T. Rudas, “Iterative scaling in curved exponential families,”
Scandinavian Journal of Statistics, vol. 42, no. 3. Wiley, pp. 832–847,
2015.
ista: Klimova A, Rudas T. 2015. Iterative scaling in curved exponential families.
Scandinavian Journal of Statistics. 42(3), 832–847.
mla: Klimova, Anna, and Tamás Rudas. “Iterative Scaling in Curved Exponential Families.”
Scandinavian Journal of Statistics, vol. 42, no. 3, Wiley, 2015, pp. 832–47,
doi:10.1111/sjos.12139.
short: A. Klimova, T. Rudas, Scandinavian Journal of Statistics 42 (2015) 832–847.
date_created: 2018-12-11T11:55:11Z
date_published: 2015-09-01T00:00:00Z
date_updated: 2021-01-12T06:54:41Z
day: '01'
department:
- _id: CaUh
doi: 10.1111/sjos.12139
intvolume: ' 42'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1307.3282
month: '09'
oa: 1
oa_version: Preprint
page: 832 - 847
publication: Scandinavian Journal of Statistics
publication_status: published
publisher: Wiley
publist_id: '5068'
quality_controlled: '1'
scopus_import: 1
status: public
title: Iterative scaling in curved exponential families
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 42
year: '2015'
...
---
_id: '2006'
abstract:
- lang: eng
text: 'The monotone secant conjecture posits a rich class of polynomial systems,
all of whose solutions are real. These systems come from the Schubert calculus
on flag manifolds, and the monotone secant conjecture is a compelling generalization
of the Shapiro conjecture for Grassmannians (Theorem of Mukhin, Tarasov, and Varchenko).
We present some theoretical evidence for this conjecture, as well as computational
evidence obtained by 1.9 teraHertz-years of computing, and we discuss some of
the phenomena we observed in our data. '
article_processing_charge: No
author:
- first_name: Nicolas
full_name: Hein, Nicolas
last_name: Hein
- first_name: Christopher
full_name: Hillar, Christopher
last_name: Hillar
- first_name: Abraham
full_name: Martin Del Campo Sanchez, Abraham
id: 4CF47F6A-F248-11E8-B48F-1D18A9856A87
last_name: Martin Del Campo Sanchez
- first_name: Frank
full_name: Sottile, Frank
last_name: Sottile
- first_name: Zach
full_name: Teitler, Zach
last_name: Teitler
citation:
ama: Hein N, Hillar C, Martin del Campo Sanchez A, Sottile F, Teitler Z. The monotone
secant conjecture in the real Schubert calculus. Experimental Mathematics.
2015;24(3):261-269. doi:10.1080/10586458.2014.980044
apa: Hein, N., Hillar, C., Martin del Campo Sanchez, A., Sottile, F., & Teitler,
Z. (2015). The monotone secant conjecture in the real Schubert calculus. Experimental
Mathematics. Taylor & Francis. https://doi.org/10.1080/10586458.2014.980044
chicago: Hein, Nicolas, Christopher Hillar, Abraham Martin del Campo Sanchez, Frank
Sottile, and Zach Teitler. “The Monotone Secant Conjecture in the Real Schubert
Calculus.” Experimental Mathematics. Taylor & Francis, 2015. https://doi.org/10.1080/10586458.2014.980044.
ieee: N. Hein, C. Hillar, A. Martin del Campo Sanchez, F. Sottile, and Z. Teitler,
“The monotone secant conjecture in the real Schubert calculus,” Experimental
Mathematics, vol. 24, no. 3. Taylor & Francis, pp. 261–269, 2015.
ista: Hein N, Hillar C, Martin del Campo Sanchez A, Sottile F, Teitler Z. 2015.
The monotone secant conjecture in the real Schubert calculus. Experimental Mathematics.
24(3), 261–269.
mla: Hein, Nicolas, et al. “The Monotone Secant Conjecture in the Real Schubert
Calculus.” Experimental Mathematics, vol. 24, no. 3, Taylor & Francis,
2015, pp. 261–69, doi:10.1080/10586458.2014.980044.
short: N. Hein, C. Hillar, A. Martin del Campo Sanchez, F. Sottile, Z. Teitler,
Experimental Mathematics 24 (2015) 261–269.
date_created: 2018-12-11T11:55:10Z
date_published: 2015-06-23T00:00:00Z
date_updated: 2021-01-12T06:54:40Z
day: '23'
department:
- _id: CaUh
doi: 10.1080/10586458.2014.980044
intvolume: ' 24'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1109.3436
month: '06'
oa: 1
oa_version: Preprint
page: 261 - 269
publication: Experimental Mathematics
publication_status: published
publisher: Taylor & Francis
publist_id: '5070'
quality_controlled: '1'
scopus_import: 1
status: public
title: The monotone secant conjecture in the real Schubert calculus
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2015'
...
---
_id: '2014'
abstract:
- lang: eng
text: The concepts of faithfulness and strong-faithfulness are important for statistical
learning of graphical models. Graphs are not sufficient for describing the association
structure of a discrete distribution. Hypergraphs representing hierarchical log-linear
models are considered instead, and the concept of parametric (strong-) faithfulness
with respect to a hypergraph is introduced. Strong-faithfulness ensures the existence
of uniformly consistent parameter estimators and enables building uniformly consistent
procedures for a hypergraph search. The strength of association in a discrete
distribution can be quantified with various measures, leading to different concepts
of strong-faithfulness. Lower and upper bounds for the proportions of distributions
that do not satisfy strong-faithfulness are computed for different parameterizations
and measures of association.
author:
- first_name: Anna
full_name: Klimova, Anna
id: 31934120-F248-11E8-B48F-1D18A9856A87
last_name: Klimova
- first_name: Caroline
full_name: Uhler, Caroline
id: 49ADD78E-F248-11E8-B48F-1D18A9856A87
last_name: Uhler
orcid: 0000-0002-7008-0216
- first_name: Tamás
full_name: Rudas, Tamás
last_name: Rudas
citation:
ama: Klimova A, Uhler C, Rudas T. Faithfulness and learning hypergraphs from discrete
distributions. Computational Statistics & Data Analysis. 2015;87(7):57-72.
doi:10.1016/j.csda.2015.01.017
apa: Klimova, A., Uhler, C., & Rudas, T. (2015). Faithfulness and learning hypergraphs
from discrete distributions. Computational Statistics & Data Analysis.
Elsevier. https://doi.org/10.1016/j.csda.2015.01.017
chicago: Klimova, Anna, Caroline Uhler, and Tamás Rudas. “Faithfulness and Learning
Hypergraphs from Discrete Distributions.” Computational Statistics & Data
Analysis. Elsevier, 2015. https://doi.org/10.1016/j.csda.2015.01.017.
ieee: A. Klimova, C. Uhler, and T. Rudas, “Faithfulness and learning hypergraphs
from discrete distributions,” Computational Statistics & Data Analysis,
vol. 87, no. 7. Elsevier, pp. 57–72, 2015.
ista: Klimova A, Uhler C, Rudas T. 2015. Faithfulness and learning hypergraphs from
discrete distributions. Computational Statistics & Data Analysis. 87(7), 57–72.
mla: Klimova, Anna, et al. “Faithfulness and Learning Hypergraphs from Discrete
Distributions.” Computational Statistics & Data Analysis, vol. 87,
no. 7, Elsevier, 2015, pp. 57–72, doi:10.1016/j.csda.2015.01.017.
short: A. Klimova, C. Uhler, T. Rudas, Computational Statistics & Data Analysis
87 (2015) 57–72.
date_created: 2018-12-11T11:55:13Z
date_published: 2015-07-01T00:00:00Z
date_updated: 2021-01-12T06:54:43Z
day: '01'
department:
- _id: CaUh
doi: 10.1016/j.csda.2015.01.017
intvolume: ' 87'
issue: '7'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1404.6617
month: '07'
oa: 1
oa_version: Preprint
page: 57 - 72
publication: Computational Statistics & Data Analysis
publication_status: published
publisher: Elsevier
publist_id: '5062'
quality_controlled: '1'
scopus_import: 1
status: public
title: Faithfulness and learning hypergraphs from discrete distributions
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 87
year: '2015'
...
---
_id: '2025'
abstract:
- lang: eng
text: Small GTP-binding proteins of the Ras superfamily play diverse roles in intracellular
trafficking. Among them, the Rab, Arf, and Rho families function in successive
steps of vesicle transport, in forming vesicles from donor membranes, directing
vesicle trafficking toward target membranes and docking vesicles onto target membranes.
These proteins act as molecular switches that are controlled by a cycle of GTP
binding and hydrolysis regulated by guanine nucleotide exchange factors (GEFs)
and GTPase-activating proteins (GAPs). In this study we explored the role of GAPs
in the regulation of the endocytic pathway using fluorescently labeled yeast mating
pheromone α-factor. Among 25 non-essential GAP mutants, we found that deletion
of the GLO3 gene, encoding Arf-GAP protein, caused defective internalization of
fluorescently labeled α-factor. Quantitative analysis revealed that glo3Δ cells
show defective α-factor binding to the cell surface. Interestingly, Ste2p, the
α-factor receptor, was mis-localized from the plasma membrane to the vacuole in
glo3Δ cells. Domain deletion mutants of Glo3p revealed that a GAP-independent
function, as well as the GAP activity, of Glo3p is important for both α-factor
binding and Ste2p localization at the cell surface. Additionally, we found that
deletion of the GLO3 gene affects the size and number of Arf1p-residing Golgi
compartments and causes a defect in transport from the TGN to the plasma membrane.
Furthermore, we demonstrated that glo3Δ cells were defective in the late endosome-to-TGN
transport pathway, but not in the early endosome-to-TGN transport pathway. These
findings suggest novel roles for Arf-GAP Glo3p in endocytic recycling of cell
surface proteins.
author:
- first_name: Daiki
full_name: Kawada, Daiki
last_name: Kawada
- first_name: Hiromu
full_name: Kobayashi, Hiromu
last_name: Kobayashi
- first_name: Tsuyoshi
full_name: Tomita, Tsuyoshi
last_name: Tomita
- first_name: Eisuke
full_name: Nakata, Eisuke
last_name: Nakata
- first_name: Makoto
full_name: Nagano, Makoto
last_name: Nagano
- first_name: Daria E
full_name: Siekhaus, Daria E
id: 3D224B9E-F248-11E8-B48F-1D18A9856A87
last_name: Siekhaus
orcid: 0000-0001-8323-8353
- first_name: Junko
full_name: Toshima, Junko
last_name: Toshima
- first_name: Jiro
full_name: Toshimaa, Jiro
last_name: Toshimaa
citation:
ama: Kawada D, Kobayashi H, Tomita T, et al. The yeast Arf-GAP Glo3p is required
for the endocytic recycling of cell surface proteins. Biochimica et Biophysica
Acta - Molecular Cell Research. 2015;1853(1):144-156. doi:10.1016/j.bbamcr.2014.10.009
apa: Kawada, D., Kobayashi, H., Tomita, T., Nakata, E., Nagano, M., Siekhaus, D.
E., … Toshimaa, J. (2015). The yeast Arf-GAP Glo3p is required for the endocytic
recycling of cell surface proteins. Biochimica et Biophysica Acta - Molecular
Cell Research. Elsevier. https://doi.org/10.1016/j.bbamcr.2014.10.009
chicago: Kawada, Daiki, Hiromu Kobayashi, Tsuyoshi Tomita, Eisuke Nakata, Makoto
Nagano, Daria E Siekhaus, Junko Toshima, and Jiro Toshimaa. “The Yeast Arf-GAP
Glo3p Is Required for the Endocytic Recycling of Cell Surface Proteins.” Biochimica
et Biophysica Acta - Molecular Cell Research. Elsevier, 2015. https://doi.org/10.1016/j.bbamcr.2014.10.009.
ieee: D. Kawada et al., “The yeast Arf-GAP Glo3p is required for the endocytic
recycling of cell surface proteins,” Biochimica et Biophysica Acta - Molecular
Cell Research, vol. 1853, no. 1. Elsevier, pp. 144–156, 2015.
ista: Kawada D, Kobayashi H, Tomita T, Nakata E, Nagano M, Siekhaus DE, Toshima
J, Toshimaa J. 2015. The yeast Arf-GAP Glo3p is required for the endocytic recycling
of cell surface proteins. Biochimica et Biophysica Acta - Molecular Cell Research.
1853(1), 144–156.
mla: Kawada, Daiki, et al. “The Yeast Arf-GAP Glo3p Is Required for the Endocytic
Recycling of Cell Surface Proteins.” Biochimica et Biophysica Acta - Molecular
Cell Research, vol. 1853, no. 1, Elsevier, 2015, pp. 144–56, doi:10.1016/j.bbamcr.2014.10.009.
short: D. Kawada, H. Kobayashi, T. Tomita, E. Nakata, M. Nagano, D.E. Siekhaus,
J. Toshima, J. Toshimaa, Biochimica et Biophysica Acta - Molecular Cell Research
1853 (2015) 144–156.
date_created: 2018-12-11T11:55:17Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2021-01-12T06:54:48Z
day: '01'
ddc:
- '570'
department:
- _id: DaSi
doi: 10.1016/j.bbamcr.2014.10.009
file:
- access_level: open_access
checksum: 5bb328edebb6a91337cadd7d63f961b7
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:12:18Z
date_updated: 2020-07-14T12:45:25Z
file_id: '4936'
file_name: IST-2016-615-v1+1_BBAMCR.pdf
file_size: 926685
relation: main_file
file_date_updated: 2020-07-14T12:45:25Z
has_accepted_license: '1'
intvolume: ' 1853'
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Submitted Version
page: 144 - 156
publication: Biochimica et Biophysica Acta - Molecular Cell Research
publication_status: published
publisher: Elsevier
publist_id: '5047'
pubrep_id: '615'
quality_controlled: '1'
scopus_import: 1
status: public
title: The yeast Arf-GAP Glo3p is required for the endocytic recycling of cell surface
proteins
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1853
year: '2015'
...
---
_id: '2030'
abstract:
- lang: eng
text: A hybrid-parallel direct-numerical-simulation method with application to turbulent
Taylor-Couette flow is presented. The Navier-Stokes equations are discretized
in cylindrical coordinates with the spectral Fourier-Galerkin method in the axial
and azimuthal directions, and high-order finite differences in the radial direction.
Time is advanced by a second-order, semi-implicit projection scheme, which requires
the solution of five Helmholtz/Poisson equations, avoids staggered grids and renders
very small slip velocities. Nonlinear terms are evaluated with the pseudospectral
method. The code is parallelized using a hybrid MPI-OpenMP strategy, which, compared
with a flat MPI parallelization, is simpler to implement, allows to reduce inter-node
communications and MPI overhead that become relevant at high processor-core counts,
and helps to contain the memory footprint. A strong scaling study shows that the
hybrid code maintains scalability up to more than 20,000 processor cores and thus
allows to perform simulations at higher resolutions than previously feasible.
In particular, it opens up the possibility to simulate turbulent Taylor-Couette
flows at Reynolds numbers up to O(105). This enables to probe hydrodynamic turbulence
in Keplerian flows in experimentally relevant regimes.
author:
- first_name: Liang
full_name: Shi, Liang
id: 374A3F1A-F248-11E8-B48F-1D18A9856A87
last_name: Shi
- first_name: Markus
full_name: Rampp, Markus
last_name: Rampp
- first_name: Björn
full_name: Hof, Björn
id: 3A374330-F248-11E8-B48F-1D18A9856A87
last_name: Hof
orcid: 0000-0003-2057-2754
- first_name: Marc
full_name: Avila, Marc
last_name: Avila
citation:
ama: Shi L, Rampp M, Hof B, Avila M. A hybrid MPI-OpenMP parallel implementation
for pseudospectral simulations with application to Taylor-Couette flow. Computers
and Fluids. 2015;106(1):1-11. doi:10.1016/j.compfluid.2014.09.021
apa: Shi, L., Rampp, M., Hof, B., & Avila, M. (2015). A hybrid MPI-OpenMP parallel
implementation for pseudospectral simulations with application to Taylor-Couette
flow. Computers and Fluids. Elsevier. https://doi.org/10.1016/j.compfluid.2014.09.021
chicago: Shi, Liang, Markus Rampp, Björn Hof, and Marc Avila. “A Hybrid MPI-OpenMP
Parallel Implementation for Pseudospectral Simulations with Application to Taylor-Couette
Flow.” Computers and Fluids. Elsevier, 2015. https://doi.org/10.1016/j.compfluid.2014.09.021.
ieee: L. Shi, M. Rampp, B. Hof, and M. Avila, “A hybrid MPI-OpenMP parallel implementation
for pseudospectral simulations with application to Taylor-Couette flow,” Computers
and Fluids, vol. 106, no. 1. Elsevier, pp. 1–11, 2015.
ista: Shi L, Rampp M, Hof B, Avila M. 2015. A hybrid MPI-OpenMP parallel implementation
for pseudospectral simulations with application to Taylor-Couette flow. Computers
and Fluids. 106(1), 1–11.
mla: Shi, Liang, et al. “A Hybrid MPI-OpenMP Parallel Implementation for Pseudospectral
Simulations with Application to Taylor-Couette Flow.” Computers and Fluids,
vol. 106, no. 1, Elsevier, 2015, pp. 1–11, doi:10.1016/j.compfluid.2014.09.021.
short: L. Shi, M. Rampp, B. Hof, M. Avila, Computers and Fluids 106 (2015) 1–11.
date_created: 2018-12-11T11:55:18Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2021-01-12T06:54:51Z
day: '01'
department:
- _id: BjHo
doi: 10.1016/j.compfluid.2014.09.021
intvolume: ' 106'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1311.2481
month: '01'
oa: 1
oa_version: Preprint
page: 1 - 11
publication: Computers and Fluids
publication_status: published
publisher: Elsevier
publist_id: '5042'
quality_controlled: '1'
scopus_import: 1
status: public
title: A hybrid MPI-OpenMP parallel implementation for pseudospectral simulations
with application to Taylor-Couette flow
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 106
year: '2015'
...
---
_id: '2035'
abstract:
- lang: eng
text: "Considering a continuous self-map and the induced endomorphism on homology,
we study the eigenvalues and eigenspaces of the latter. Taking a filtration of
representations, we define the persistence of the eigenspaces, effectively introducing
a hierarchical organization of the map. The algorithm that computes this information
for a finite sample is proved to be stable, and to give the correct answer for
a sufficiently dense sample. Results computed with an implementation of the algorithm
provide evidence of its practical utility.\r\n"
acknowledgement: This research is partially supported by the Toposys project FP7-ICT-318493-STREP,
by ESF under the ACAT Research Network Programme, by the Russian Government under
mega project 11.G34.31.0053, and by the Polish National Science Center under Grant
No. N201 419639.
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Grzegorz
full_name: Jablonski, Grzegorz
id: 4483EF78-F248-11E8-B48F-1D18A9856A87
last_name: Jablonski
orcid: 0000-0002-3536-9866
- first_name: Marian
full_name: Mrozek, Marian
last_name: Mrozek
citation:
ama: Edelsbrunner H, Jablonski G, Mrozek M. The persistent homology of a self-map.
Foundations of Computational Mathematics. 2015;15(5):1213-1244. doi:10.1007/s10208-014-9223-y
apa: Edelsbrunner, H., Jablonski, G., & Mrozek, M. (2015). The persistent homology
of a self-map. Foundations of Computational Mathematics. Springer. https://doi.org/10.1007/s10208-014-9223-y
chicago: Edelsbrunner, Herbert, Grzegorz Jablonski, and Marian Mrozek. “The Persistent
Homology of a Self-Map.” Foundations of Computational Mathematics. Springer,
2015. https://doi.org/10.1007/s10208-014-9223-y.
ieee: H. Edelsbrunner, G. Jablonski, and M. Mrozek, “The persistent homology of
a self-map,” Foundations of Computational Mathematics, vol. 15, no. 5.
Springer, pp. 1213–1244, 2015.
ista: Edelsbrunner H, Jablonski G, Mrozek M. 2015. The persistent homology of a
self-map. Foundations of Computational Mathematics. 15(5), 1213–1244.
mla: Edelsbrunner, Herbert, et al. “The Persistent Homology of a Self-Map.” Foundations
of Computational Mathematics, vol. 15, no. 5, Springer, 2015, pp. 1213–44,
doi:10.1007/s10208-014-9223-y.
short: H. Edelsbrunner, G. Jablonski, M. Mrozek, Foundations of Computational Mathematics
15 (2015) 1213–1244.
date_created: 2018-12-11T11:55:20Z
date_published: 2015-10-01T00:00:00Z
date_updated: 2021-01-12T06:54:53Z
day: '01'
ddc:
- '000'
department:
- _id: HeEd
doi: 10.1007/s10208-014-9223-y
ec_funded: 1
file:
- access_level: open_access
checksum: 3566f3a8b0c1bc550e62914a88c584ff
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:08:10Z
date_updated: 2020-07-14T12:45:26Z
file_id: '4670'
file_name: IST-2016-486-v1+1_s10208-014-9223-y.pdf
file_size: 1317546
relation: main_file
file_date_updated: 2020-07-14T12:45:26Z
has_accepted_license: '1'
intvolume: ' 15'
issue: '5'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: 1213 - 1244
project:
- _id: 255D761E-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '318493'
name: Topological Complex Systems
publication: Foundations of Computational Mathematics
publication_status: published
publisher: Springer
publist_id: '5022'
pubrep_id: '486'
quality_controlled: '1'
scopus_import: 1
status: public
title: The persistent homology of a self-map
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2015'
...
---
_id: '2034'
abstract:
- lang: eng
text: Opacity is a generic security property, that has been defined on (non-probabilistic)
transition systems and later on Markov chains with labels. For a secret predicate,
given as a subset of runs, and a function describing the view of an external observer,
the value of interest for opacity is a measure of the set of runs disclosing the
secret. We extend this definition to the richer framework of Markov decision processes,
where non-deterministicchoice is combined with probabilistic transitions, and
we study related decidability problems with partial or complete observation hypotheses
for the schedulers. We prove that all questions are decidable with complete observation
and ω-regular secrets. With partial observation, we prove that all quantitative
questions are undecidable but the question whether a system is almost surely non-opaquebecomes
decidable for a restricted class of ω-regular secrets, as well as for all ω-regular
secrets under finite-memory schedulers.
author:
- first_name: Béatrice
full_name: Bérard, Béatrice
last_name: Bérard
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Nathalie
full_name: Sznajder, Nathalie
last_name: Sznajder
citation:
ama: Bérard B, Chatterjee K, Sznajder N. Probabilistic opacity for Markov decision
processes. Information Processing Letters. 2015;115(1):52-59. doi:10.1016/j.ipl.2014.09.001
apa: Bérard, B., Chatterjee, K., & Sznajder, N. (2015). Probabilistic opacity
for Markov decision processes. Information Processing Letters. Elsevier.
https://doi.org/10.1016/j.ipl.2014.09.001
chicago: Bérard, Béatrice, Krishnendu Chatterjee, and Nathalie Sznajder. “Probabilistic
Opacity for Markov Decision Processes.” Information Processing Letters.
Elsevier, 2015. https://doi.org/10.1016/j.ipl.2014.09.001.
ieee: B. Bérard, K. Chatterjee, and N. Sznajder, “Probabilistic opacity for Markov
decision processes,” Information Processing Letters, vol. 115, no. 1.
Elsevier, pp. 52–59, 2015.
ista: Bérard B, Chatterjee K, Sznajder N. 2015. Probabilistic opacity for Markov
decision processes. Information Processing Letters. 115(1), 52–59.
mla: Bérard, Béatrice, et al. “Probabilistic Opacity for Markov Decision Processes.”
Information Processing Letters, vol. 115, no. 1, Elsevier, 2015, pp. 52–59,
doi:10.1016/j.ipl.2014.09.001.
short: B. Bérard, K. Chatterjee, N. Sznajder, Information Processing Letters 115
(2015) 52–59.
date_created: 2018-12-11T11:55:20Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2021-01-12T06:54:52Z
day: '01'
department:
- _id: KrCh
doi: 10.1016/j.ipl.2014.09.001
ec_funded: 1
intvolume: ' 115'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1407.4225
month: '01'
oa: 1
oa_version: Preprint
page: 52 - 59
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
publication: ' Information Processing Letters'
publication_status: published
publisher: Elsevier
publist_id: '5025'
quality_controlled: '1'
scopus_import: 1
status: public
title: Probabilistic opacity for Markov decision processes
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 115
year: '2015'
...
---
_id: '2085'
abstract:
- lang: eng
text: 'We study the spectrum of a large system of N identical bosons interacting
via a two-body potential with strength 1/N. In this mean-field regime, Bogoliubov''s
theory predicts that the spectrum of the N-particle Hamiltonian can be approximated
by that of an effective quadratic Hamiltonian acting on Fock space, which describes
the fluctuations around a condensed state. Recently, Bogoliubov''s theory has
been justified rigorously in the case that the low-energy eigenvectors of the
N-particle Hamiltonian display complete condensation in the unique minimizer of
the corresponding Hartree functional. In this paper, we shall justify Bogoliubov''s
theory for the high-energy part of the spectrum of the N-particle Hamiltonian
corresponding to (non-linear) excited states of the Hartree functional. Moreover,
we shall extend the existing results on the excitation spectrum to the case of
non-uniqueness and/or degeneracy of the Hartree minimizer. In particular, the
latter covers the case of rotating Bose gases, when the rotation speed is large
enough to break the symmetry and to produce multiple quantized vortices in the
Hartree minimizer. '
author:
- first_name: Phan
full_name: Nam, Phan
id: 404092F4-F248-11E8-B48F-1D18A9856A87
last_name: Nam
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Nam P, Seiringer R. Collective excitations of Bose gases in the mean-field
regime. Archive for Rational Mechanics and Analysis. 2015;215(2):381-417.
doi:10.1007/s00205-014-0781-6
apa: Nam, P., & Seiringer, R. (2015). Collective excitations of Bose gases in
the mean-field regime. Archive for Rational Mechanics and Analysis. Springer.
https://doi.org/10.1007/s00205-014-0781-6
chicago: Nam, Phan, and Robert Seiringer. “Collective Excitations of Bose Gases
in the Mean-Field Regime.” Archive for Rational Mechanics and Analysis.
Springer, 2015. https://doi.org/10.1007/s00205-014-0781-6.
ieee: P. Nam and R. Seiringer, “Collective excitations of Bose gases in the mean-field
regime,” Archive for Rational Mechanics and Analysis, vol. 215, no. 2.
Springer, pp. 381–417, 2015.
ista: Nam P, Seiringer R. 2015. Collective excitations of Bose gases in the mean-field
regime. Archive for Rational Mechanics and Analysis. 215(2), 381–417.
mla: Nam, Phan, and Robert Seiringer. “Collective Excitations of Bose Gases in the
Mean-Field Regime.” Archive for Rational Mechanics and Analysis, vol. 215,
no. 2, Springer, 2015, pp. 381–417, doi:10.1007/s00205-014-0781-6.
short: P. Nam, R. Seiringer, Archive for Rational Mechanics and Analysis 215 (2015)
381–417.
date_created: 2018-12-11T11:55:37Z
date_published: 2015-02-01T00:00:00Z
date_updated: 2021-01-12T06:55:13Z
day: '01'
department:
- _id: RoSe
doi: 10.1007/s00205-014-0781-6
intvolume: ' 215'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1402.1153
month: '02'
oa: 1
oa_version: Preprint
page: 381 - 417
publication: Archive for Rational Mechanics and Analysis
publication_status: published
publisher: Springer
publist_id: '4951'
quality_controlled: '1'
scopus_import: 1
status: public
title: Collective excitations of Bose gases in the mean-field regime
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 215
year: '2015'
...
---
_id: '2166'
abstract:
- lang: eng
text: 'We consider the spectral statistics of large random band matrices on mesoscopic
energy scales. We show that the correlation function of the local eigenvalue density
exhibits a universal power law behaviour that differs from the Wigner-Dyson- Mehta
statistics. This law had been predicted in the physics literature by Altshuler
and Shklovskii in (Zh Eksp Teor Fiz (Sov Phys JETP) 91(64):220(127), 1986); it
describes the correlations of the eigenvalue density in general metallic sampleswith
weak disorder. Our result rigorously establishes the Altshuler-Shklovskii formulas
for band matrices. In two dimensions, where the leading term vanishes owing to
an algebraic cancellation, we identify the first non-vanishing term and show that
it differs substantially from the prediction of Kravtsov and Lerner in (Phys Rev
Lett 74:2563-2566, 1995). The proof is given in the current paper and its companion
(Ann. H. Poincaré. arXiv:1309.5107, 2014). '
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Antti
full_name: Knowles, Antti
last_name: Knowles
citation:
ama: 'Erdös L, Knowles A. The Altshuler-Shklovskii formulas for random band matrices
I: the unimodular case. Communications in Mathematical Physics. 2015;333(3):1365-1416.
doi:10.1007/s00220-014-2119-5'
apa: 'Erdös, L., & Knowles, A. (2015). The Altshuler-Shklovskii formulas for
random band matrices I: the unimodular case. Communications in Mathematical
Physics. Springer. https://doi.org/10.1007/s00220-014-2119-5'
chicago: 'Erdös, László, and Antti Knowles. “The Altshuler-Shklovskii Formulas for
Random Band Matrices I: The Unimodular Case.” Communications in Mathematical
Physics. Springer, 2015. https://doi.org/10.1007/s00220-014-2119-5.'
ieee: 'L. Erdös and A. Knowles, “The Altshuler-Shklovskii formulas for random band
matrices I: the unimodular case,” Communications in Mathematical Physics,
vol. 333, no. 3. Springer, pp. 1365–1416, 2015.'
ista: 'Erdös L, Knowles A. 2015. The Altshuler-Shklovskii formulas for random band
matrices I: the unimodular case. Communications in Mathematical Physics. 333(3),
1365–1416.'
mla: 'Erdös, László, and Antti Knowles. “The Altshuler-Shklovskii Formulas for Random
Band Matrices I: The Unimodular Case.” Communications in Mathematical Physics,
vol. 333, no. 3, Springer, 2015, pp. 1365–416, doi:10.1007/s00220-014-2119-5.'
short: L. Erdös, A. Knowles, Communications in Mathematical Physics 333 (2015) 1365–1416.
date_created: 2018-12-11T11:56:05Z
date_published: 2015-02-01T00:00:00Z
date_updated: 2021-01-12T06:55:43Z
day: '01'
department:
- _id: LaEr
doi: 10.1007/s00220-014-2119-5
intvolume: ' 333'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1309.5106
month: '02'
oa: 1
oa_version: Preprint
page: 1365 - 1416
publication: Communications in Mathematical Physics
publication_status: published
publisher: Springer
publist_id: '4818'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'The Altshuler-Shklovskii formulas for random band matrices I: the unimodular
case'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 333
year: '2015'
...
---
_id: '1832'
abstract:
- lang: eng
text: 'Linearizability of concurrent data structures is usually proved by monolithic
simulation arguments relying on the identification of the so-called linearization
points. Regrettably, such proofs, whether manual or automatic, are often complicated
and scale poorly to advanced non-blocking concurrency patterns, such as helping
and optimistic updates. In response, we propose a more modular way of checking
linearizability of concurrent queue algorithms that does not involve identifying
linearization points. We reduce the task of proving linearizability with respect
to the queue specification to establishing four basic properties, each of which
can be proved independently by simpler arguments. As a demonstration of our approach,
we verify the Herlihy and Wing queue, an algorithm that is challenging to verify
by a simulation proof. '
article_number: '20'
article_processing_charge: No
article_type: original
author:
- first_name: Soham
full_name: Chakraborty, Soham
last_name: Chakraborty
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Ali
full_name: Sezgin, Ali
last_name: Sezgin
- first_name: Viktor
full_name: Vafeiadis, Viktor
last_name: Vafeiadis
citation:
ama: Chakraborty S, Henzinger TA, Sezgin A, Vafeiadis V. Aspect-oriented linearizability
proofs. Logical Methods in Computer Science. 2015;11(1). doi:10.2168/LMCS-11(1:20)2015
apa: Chakraborty, S., Henzinger, T. A., Sezgin, A., & Vafeiadis, V. (2015).
Aspect-oriented linearizability proofs. Logical Methods in Computer Science.
International Federation of Computational Logic. https://doi.org/10.2168/LMCS-11(1:20)2015
chicago: Chakraborty, Soham, Thomas A Henzinger, Ali Sezgin, and Viktor Vafeiadis.
“Aspect-Oriented Linearizability Proofs.” Logical Methods in Computer Science.
International Federation of Computational Logic, 2015. https://doi.org/10.2168/LMCS-11(1:20)2015.
ieee: S. Chakraborty, T. A. Henzinger, A. Sezgin, and V. Vafeiadis, “Aspect-oriented
linearizability proofs,” Logical Methods in Computer Science, vol. 11,
no. 1. International Federation of Computational Logic, 2015.
ista: Chakraborty S, Henzinger TA, Sezgin A, Vafeiadis V. 2015. Aspect-oriented
linearizability proofs. Logical Methods in Computer Science. 11(1), 20.
mla: Chakraborty, Soham, et al. “Aspect-Oriented Linearizability Proofs.” Logical
Methods in Computer Science, vol. 11, no. 1, 20, International Federation
of Computational Logic, 2015, doi:10.2168/LMCS-11(1:20)2015.
short: S. Chakraborty, T.A. Henzinger, A. Sezgin, V. Vafeiadis, Logical Methods
in Computer Science 11 (2015).
date_created: 2018-12-11T11:54:15Z
date_published: 2015-04-01T00:00:00Z
date_updated: 2023-02-23T10:38:13Z
day: '01'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.2168/LMCS-11(1:20)2015
ec_funded: 1
file:
- access_level: open_access
checksum: 7370e164d0a731f442424a92669efc34
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:11:27Z
date_updated: 2020-07-14T12:45:17Z
file_id: '4881'
file_name: IST-2015-390-v1+1_1502.07639.pdf
file_size: 380203
relation: main_file
file_date_updated: 2020-07-14T12:45:17Z
has_accepted_license: '1'
intvolume: ' 11'
issue: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nd/4.0/
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
publication: Logical Methods in Computer Science
publication_status: published
publisher: International Federation of Computational Logic
publist_id: '5271'
pubrep_id: '390'
quality_controlled: '1'
related_material:
record:
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relation: earlier_version
status: public
scopus_import: 1
status: public
title: Aspect-oriented linearizability proofs
tmp:
image: /image/cc_by_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nd/4.0/legalcode
name: Creative Commons Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0)
short: CC BY-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2015'
...
---
_id: '2271'
abstract:
- lang: eng
text: "A class of valued constraint satisfaction problems (VCSPs) is characterised
by a valued constraint language, a fixed set of cost functions on a finite domain.
Finite-valued constraint languages contain functions that take on rational costs
and general-valued constraint languages contain functions that take on rational
or infinite costs. An instance of the problem is specified by a sum of functions
from the language with the goal to minimise the sum. This framework includes and
generalises well-studied constraint satisfaction problems (CSPs) and maximum constraint
satisfaction problems (Max-CSPs).\r\nOur main result is a precise algebraic characterisation
of valued constraint languages whose instances can be solved exactly by the basic
linear programming relaxation (BLP). For a general-valued constraint language
Γ, BLP is a decision procedure for Γ if and only if Γ admits a symmetric fractional
polymorphism of every arity. For a finite-valued constraint language Γ, BLP is
a decision procedure if and only if Γ admits a symmetric fractional polymorphism
of some arity, or equivalently, if Γ admits a symmetric fractional polymorphism
of arity 2.\r\nUsing these results, we obtain tractability of several novel and
previously widely-open classes of VCSPs, including problems over valued constraint
languages that are: (1) submodular on arbitrary lattices; (2) bisubmodular (also
known as k-submodular) on arbitrary finite domains; (3) weakly (and hence strongly)
tree-submodular on arbitrary trees. "
author:
- first_name: Vladimir
full_name: Kolmogorov, Vladimir
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
- first_name: Johan
full_name: Thapper, Johan
last_name: Thapper
- first_name: Stanislav
full_name: Živný, Stanislav
last_name: Živný
citation:
ama: Kolmogorov V, Thapper J, Živný S. The power of linear programming for general-valued
CSPs. SIAM Journal on Computing. 2015;44(1):1-36. doi:10.1137/130945648
apa: Kolmogorov, V., Thapper, J., & Živný, S. (2015). The power of linear programming
for general-valued CSPs. SIAM Journal on Computing. SIAM. https://doi.org/10.1137/130945648
chicago: Kolmogorov, Vladimir, Johan Thapper, and Stanislav Živný. “The Power of
Linear Programming for General-Valued CSPs.” SIAM Journal on Computing.
SIAM, 2015. https://doi.org/10.1137/130945648.
ieee: V. Kolmogorov, J. Thapper, and S. Živný, “The power of linear programming
for general-valued CSPs,” SIAM Journal on Computing, vol. 44, no. 1. SIAM,
pp. 1–36, 2015.
ista: Kolmogorov V, Thapper J, Živný S. 2015. The power of linear programming for
general-valued CSPs. SIAM Journal on Computing. 44(1), 1–36.
mla: Kolmogorov, Vladimir, et al. “The Power of Linear Programming for General-Valued
CSPs.” SIAM Journal on Computing, vol. 44, no. 1, SIAM, 2015, pp. 1–36,
doi:10.1137/130945648.
short: V. Kolmogorov, J. Thapper, S. Živný, SIAM Journal on Computing 44 (2015)
1–36.
date_created: 2018-12-11T11:56:41Z
date_published: 2015-02-01T00:00:00Z
date_updated: 2023-02-23T10:46:30Z
day: '01'
department:
- _id: VlKo
doi: 10.1137/130945648
external_id:
arxiv:
- '1311.4219'
intvolume: ' 44'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1311.4219
month: '02'
oa: 1
oa_version: Preprint
page: 1 - 36
publication: SIAM Journal on Computing
publication_status: published
publisher: SIAM
publist_id: '4673'
quality_controlled: '1'
related_material:
record:
- id: '2518'
relation: earlier_version
status: public
scopus_import: 1
status: public
title: The power of linear programming for general-valued CSPs
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 44
year: '2015'
...
---
_id: '1598'
abstract:
- lang: eng
text: 'We consider Markov decision processes (MDPs) with specifications given as
Büchi (liveness) objectives, and examine the problem of computing the set of almost-sure
winning vertices such that the objective can be ensured with probability 1 from
these vertices. We study for the first time the average-case complexity of the
classical algorithm for computing the set of almost-sure winning vertices for
MDPs with Büchi objectives. Our contributions are as follows: First, we show that
for MDPs with constant out-degree the expected number of iterations is at most
logarithmic and the average-case running time is linear (as compared to the worst-case
linear number of iterations and quadratic time complexity). Second, for the average-case
analysis over all MDPs we show that the expected number of iterations is constant
and the average-case running time is linear (again as compared to the worst-case
linear number of iterations and quadratic time complexity). Finally we also show
that when all MDPs are equally likely, the probability that the classical algorithm
requires more than a constant number of iterations is exponentially small.'
acknowledgement: "The research was supported by FWF Grant No. P 23499-N23, FWF NFN
Grant No. S11407-N23 (RiSE), ERC Start Grant (279307: Graph Games), and the Microsoft
Faculty Fellows Award. Nisarg Shah is also supported by NSF Grant CCF-1215883.\r\n"
article_processing_charge: No
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Manas
full_name: Joglekar, Manas
last_name: Joglekar
- first_name: Nisarg
full_name: Shah, Nisarg
last_name: Shah
citation:
ama: Chatterjee K, Joglekar M, Shah N. Average case analysis of the classical algorithm
for Markov decision processes with Büchi objectives. Theoretical Computer Science.
2015;573(3):71-89. doi:10.1016/j.tcs.2015.01.050
apa: Chatterjee, K., Joglekar, M., & Shah, N. (2015). Average case analysis
of the classical algorithm for Markov decision processes with Büchi objectives.
Theoretical Computer Science. Elsevier. https://doi.org/10.1016/j.tcs.2015.01.050
chicago: Chatterjee, Krishnendu, Manas Joglekar, and Nisarg Shah. “Average Case
Analysis of the Classical Algorithm for Markov Decision Processes with Büchi Objectives.”
Theoretical Computer Science. Elsevier, 2015. https://doi.org/10.1016/j.tcs.2015.01.050.
ieee: K. Chatterjee, M. Joglekar, and N. Shah, “Average case analysis of the classical
algorithm for Markov decision processes with Büchi objectives,” Theoretical
Computer Science, vol. 573, no. 3. Elsevier, pp. 71–89, 2015.
ista: Chatterjee K, Joglekar M, Shah N. 2015. Average case analysis of the classical
algorithm for Markov decision processes with Büchi objectives. Theoretical Computer
Science. 573(3), 71–89.
mla: Chatterjee, Krishnendu, et al. “Average Case Analysis of the Classical Algorithm
for Markov Decision Processes with Büchi Objectives.” Theoretical Computer
Science, vol. 573, no. 3, Elsevier, 2015, pp. 71–89, doi:10.1016/j.tcs.2015.01.050.
short: K. Chatterjee, M. Joglekar, N. Shah, Theoretical Computer Science 573 (2015)
71–89.
date_created: 2018-12-11T11:52:56Z
date_published: 2015-03-30T00:00:00Z
date_updated: 2023-02-23T10:55:03Z
day: '30'
department:
- _id: KrCh
doi: 10.1016/j.tcs.2015.01.050
ec_funded: 1
external_id:
arxiv:
- '1202.4175'
intvolume: ' 573'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1202.4175
month: '03'
oa: 1
oa_version: Preprint
page: 71 - 89
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
publication: Theoretical Computer Science
publication_status: published
publisher: Elsevier
publist_id: '5571'
quality_controlled: '1'
related_material:
record:
- id: '2715'
relation: earlier_version
status: public
scopus_import: 1
status: public
title: Average case analysis of the classical algorithm for Markov decision processes
with Büchi objectives
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 573
year: '2015'
...
---
_id: '1805'
abstract:
- lang: eng
text: 'We consider the problem of deciding whether the persistent homology group
of a simplicial pair (K,L) can be realized as the homology H∗(X) of some complex
X with L ⊂ X ⊂ K. We show that this problem is NP-complete even if K is embedded
in double-struck R3. As a consequence, we show that it is NP-hard to simplify
level and sublevel sets of scalar functions on double-struck S3 within a given
tolerance constraint. This problem has relevance to the visualization of medical
images by isosurfaces. We also show an implication to the theory of well groups
of scalar functions: not every well group can be realized by some level set, and
deciding whether a well group can be realized is NP-hard.'
author:
- first_name: Dominique
full_name: Attali, Dominique
last_name: Attali
- first_name: Ulrich
full_name: Bauer, Ulrich
id: 2ADD483A-F248-11E8-B48F-1D18A9856A87
last_name: Bauer
orcid: 0000-0002-9683-0724
- first_name: Olivier
full_name: Devillers, Olivier
last_name: Devillers
- first_name: Marc
full_name: Glisse, Marc
last_name: Glisse
- first_name: André
full_name: Lieutier, André
last_name: Lieutier
citation:
ama: 'Attali D, Bauer U, Devillers O, Glisse M, Lieutier A. Homological reconstruction
and simplification in R3. Computational Geometry: Theory and Applications.
2015;48(8):606-621. doi:10.1016/j.comgeo.2014.08.010'
apa: 'Attali, D., Bauer, U., Devillers, O., Glisse, M., & Lieutier, A. (2015).
Homological reconstruction and simplification in R3. Computational Geometry:
Theory and Applications. Elsevier. https://doi.org/10.1016/j.comgeo.2014.08.010'
chicago: 'Attali, Dominique, Ulrich Bauer, Olivier Devillers, Marc Glisse, and André
Lieutier. “Homological Reconstruction and Simplification in R3.” Computational
Geometry: Theory and Applications. Elsevier, 2015. https://doi.org/10.1016/j.comgeo.2014.08.010.'
ieee: 'D. Attali, U. Bauer, O. Devillers, M. Glisse, and A. Lieutier, “Homological
reconstruction and simplification in R3,” Computational Geometry: Theory and
Applications, vol. 48, no. 8. Elsevier, pp. 606–621, 2015.'
ista: 'Attali D, Bauer U, Devillers O, Glisse M, Lieutier A. 2015. Homological reconstruction
and simplification in R3. Computational Geometry: Theory and Applications. 48(8),
606–621.'
mla: 'Attali, Dominique, et al. “Homological Reconstruction and Simplification in
R3.” Computational Geometry: Theory and Applications, vol. 48, no. 8, Elsevier,
2015, pp. 606–21, doi:10.1016/j.comgeo.2014.08.010.'
short: 'D. Attali, U. Bauer, O. Devillers, M. Glisse, A. Lieutier, Computational
Geometry: Theory and Applications 48 (2015) 606–621.'
date_created: 2018-12-11T11:54:06Z
date_published: 2015-06-03T00:00:00Z
date_updated: 2023-02-23T10:59:19Z
day: '03'
department:
- _id: HeEd
doi: 10.1016/j.comgeo.2014.08.010
ec_funded: 1
intvolume: ' 48'
issue: '8'
language:
- iso: eng
month: '06'
oa_version: None
page: 606 - 621
project:
- _id: 255D761E-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '318493'
name: Topological Complex Systems
publication: 'Computational Geometry: Theory and Applications'
publication_status: published
publisher: Elsevier
publist_id: '5305'
quality_controlled: '1'
related_material:
record:
- id: '2812'
relation: earlier_version
status: public
scopus_import: 1
status: public
title: Homological reconstruction and simplification in R3
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 48
year: '2015'
...
---
_id: '1731'
abstract:
- lang: eng
text: 'We consider two-player zero-sum games on graphs. These games can be classified
on the basis of the information of the players and on the mode of interaction
between them. On the basis of information the classification is as follows: (a)
partial-observation (both players have partial view of the game); (b) one-sided
complete-observation (one player has complete observation); and (c) complete-observation
(both players have complete view of the game). On the basis of mode of interaction
we have the following classification: (a) concurrent (both players interact simultaneously);
and (b) turn-based (both players interact in turn). The two sources of randomness
in these games are randomness in transition function and randomness in strategies.
In general, randomized strategies are more powerful than deterministic strategies,
and randomness in transitions gives more general classes of games. In this work
we present a complete characterization for the classes of games where randomness
is not helpful in: (a) the transition function probabilistic transition can be
simulated by deterministic transition); and (b) strategies (pure strategies are
as powerful as randomized strategies). As consequence of our characterization
we obtain new undecidability results for these games. '
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Laurent
full_name: Doyen, Laurent
last_name: Doyen
- first_name: Hugo
full_name: Gimbert, Hugo
last_name: Gimbert
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
citation:
ama: Chatterjee K, Doyen L, Gimbert H, Henzinger TA. Randomness for free. Information
and Computation. 2015;245(12):3-16. doi:10.1016/j.ic.2015.06.003
apa: Chatterjee, K., Doyen, L., Gimbert, H., & Henzinger, T. A. (2015). Randomness
for free. Information and Computation. Elsevier. https://doi.org/10.1016/j.ic.2015.06.003
chicago: Chatterjee, Krishnendu, Laurent Doyen, Hugo Gimbert, and Thomas A Henzinger.
“Randomness for Free.” Information and Computation. Elsevier, 2015. https://doi.org/10.1016/j.ic.2015.06.003.
ieee: K. Chatterjee, L. Doyen, H. Gimbert, and T. A. Henzinger, “Randomness for
free,” Information and Computation, vol. 245, no. 12. Elsevier, pp. 3–16,
2015.
ista: Chatterjee K, Doyen L, Gimbert H, Henzinger TA. 2015. Randomness for free.
Information and Computation. 245(12), 3–16.
mla: Chatterjee, Krishnendu, et al. “Randomness for Free.” Information and Computation,
vol. 245, no. 12, Elsevier, 2015, pp. 3–16, doi:10.1016/j.ic.2015.06.003.
short: K. Chatterjee, L. Doyen, H. Gimbert, T.A. Henzinger, Information and Computation
245 (2015) 3–16.
date_created: 2018-12-11T11:53:42Z
date_published: 2015-12-01T00:00:00Z
date_updated: 2023-02-23T11:45:42Z
day: '01'
department:
- _id: KrCh
- _id: ToHe
doi: 10.1016/j.ic.2015.06.003
ec_funded: 1
intvolume: ' 245'
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1006.0673
month: '12'
oa: 1
oa_version: Preprint
page: 3 - 16
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25EFB36C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '215543'
name: COMponent-Based Embedded Systems design Techniques
- _id: 25F1337C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '214373'
name: Design for Embedded Systems
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
publication: Information and Computation
publication_status: published
publisher: Elsevier
publist_id: '5395'
quality_controlled: '1'
related_material:
record:
- id: '3856'
relation: earlier_version
status: public
scopus_import: 1
status: public
title: Randomness for free
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 245
year: '2015'
...
---
_id: '1856'
abstract:
- lang: eng
text: 'The traditional synthesis question given a specification asks for the automatic
construction of a system that satisfies the specification, whereas often there
exists a preference order among the different systems that satisfy the given specification.
Under a probabilistic assumption about the possible inputs, such a preference
order is naturally expressed by a weighted automaton, which assigns to each word
a value, such that a system is preferred if it generates a higher expected value.
We solve the following optimal synthesis problem: given an omega-regular specification,
a Markov chain that describes the distribution of inputs, and a weighted automaton
that measures how well a system satisfies the given specification under the input
assumption, synthesize a system that optimizes the measured value. For safety
specifications and quantitative measures that are defined by mean-payoff automata,
the optimal synthesis problem reduces to finding a strategy in a Markov decision
process (MDP) that is optimal for a long-run average reward objective, which can
be achieved in polynomial time. For general omega-regular specifications along
with mean-payoff automata, the solution rests on a new, polynomial-time algorithm
for computing optimal strategies in MDPs with mean-payoff parity objectives. Our
algorithm constructs optimal strategies that consist of two memoryless strategies
and a counter. The counter is in general not bounded. To obtain a finite-state
system, we show how to construct an ε-optimal strategy with a bounded counter,
for all ε > 0. Furthermore, we show how to decide in polynomial time if it
is possible to construct an optimal finite-state system (i.e., a system without
a counter) for a given specification. We have implemented our approach and the
underlying algorithms in a tool that takes qualitative and quantitative specifications
and automatically constructs a system that satisfies the qualitative specification
and optimizes the quantitative specification, if such a system exists. We present
some experimental results showing optimal systems that were automatically generated
in this way.'
article_number: '9'
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Barbara
full_name: Jobstmann, Barbara
last_name: Jobstmann
- first_name: Rohit
full_name: Singh, Rohit
last_name: Singh
citation:
ama: Chatterjee K, Henzinger TA, Jobstmann B, Singh R. Measuring and synthesizing
systems in probabilistic environments. Journal of the ACM. 2015;62(1).
doi:10.1145/2699430
apa: Chatterjee, K., Henzinger, T. A., Jobstmann, B., & Singh, R. (2015). Measuring
and synthesizing systems in probabilistic environments. Journal of the ACM.
ACM. https://doi.org/10.1145/2699430
chicago: Chatterjee, Krishnendu, Thomas A Henzinger, Barbara Jobstmann, and Rohit
Singh. “Measuring and Synthesizing Systems in Probabilistic Environments.” Journal
of the ACM. ACM, 2015. https://doi.org/10.1145/2699430.
ieee: K. Chatterjee, T. A. Henzinger, B. Jobstmann, and R. Singh, “Measuring and
synthesizing systems in probabilistic environments,” Journal of the ACM,
vol. 62, no. 1. ACM, 2015.
ista: Chatterjee K, Henzinger TA, Jobstmann B, Singh R. 2015. Measuring and synthesizing
systems in probabilistic environments. Journal of the ACM. 62(1), 9.
mla: Chatterjee, Krishnendu, et al. “Measuring and Synthesizing Systems in Probabilistic
Environments.” Journal of the ACM, vol. 62, no. 1, 9, ACM, 2015, doi:10.1145/2699430.
short: K. Chatterjee, T.A. Henzinger, B. Jobstmann, R. Singh, Journal of the ACM
62 (2015).
date_created: 2018-12-11T11:54:23Z
date_published: 2015-02-01T00:00:00Z
date_updated: 2023-02-23T11:46:04Z
day: '01'
department:
- _id: KrCh
- _id: ToHe
doi: 10.1145/2699430
ec_funded: 1
intvolume: ' 62'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1004.0739
month: '02'
oa: 1
oa_version: Preprint
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
publication: Journal of the ACM
publication_status: published
publisher: ACM
publist_id: '5244'
quality_controlled: '1'
related_material:
record:
- id: '3864'
relation: earlier_version
status: public
scopus_import: 1
status: public
title: Measuring and synthesizing systems in probabilistic environments
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 62
year: '2015'
...
---
_id: '1661'
abstract:
- lang: eng
text: The computation of the winning set for one-pair Streett objectives and for
k-pair Streett objectives in (standard) graphs as well as in game graphs are central
problems in computer-aided verification, with application to the verification
of closed systems with strong fairness conditions, the verification of open systems,
checking interface compatibility, well-formed ness of specifications, and the
synthesis of reactive systems. We give faster algorithms for the computation of
the winning set for (1) one-pair Streett objectives (aka parity-3 problem) in
game graphs and (2) for k-pair Streett objectives in graphs. For both problems
this represents the first improvement in asymptotic running time in 15 years.
acknowledgement: 'K. C. is supported by the Austrian Science Fund (FWF): P23499-N23
and S11407-N23 (RiSE), an ERC Start Grant (279307: Graph Games), and a Microsoft
Faculty Fellows Award. M. H. is supported by the Austrian Science Fund (FWF): P23499-N23
and the Vienna Science and Technology Fund (WWTF) grant ICT10-002. V. L. is supported
by the Vienna Science and Technology Fund (WWTF) grant ICT10-002. The research leading
to these results has received funding from the European Research Council under the
European Union’s Seventh Framework Programme (FP/2007-2013) / ERC Grant Agreement
no. 340506.'
article_number: '7174888'
article_processing_charge: No
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Veronika
full_name: Loitzenbauer, Veronika
last_name: Loitzenbauer
citation:
ama: 'Chatterjee K, Henzinger MH, Loitzenbauer V. Improved algorithms for one-pair
and k-pair Streett objectives. In: Proceedings - Symposium on Logic in Computer
Science. Vol 2015-July. IEEE; 2015. doi:10.1109/LICS.2015.34'
apa: 'Chatterjee, K., Henzinger, M. H., & Loitzenbauer, V. (2015). Improved
algorithms for one-pair and k-pair Streett objectives. In Proceedings - Symposium
on Logic in Computer Science (Vol. 2015–July). Kyoto, Japan: IEEE. https://doi.org/10.1109/LICS.2015.34'
chicago: Chatterjee, Krishnendu, Monika H Henzinger, and Veronika Loitzenbauer.
“Improved Algorithms for One-Pair and k-Pair Streett Objectives.” In Proceedings
- Symposium on Logic in Computer Science, Vol. 2015–July. IEEE, 2015. https://doi.org/10.1109/LICS.2015.34.
ieee: K. Chatterjee, M. H. Henzinger, and V. Loitzenbauer, “Improved algorithms
for one-pair and k-pair Streett objectives,” in Proceedings - Symposium on
Logic in Computer Science, Kyoto, Japan, 2015, vol. 2015–July.
ista: 'Chatterjee K, Henzinger MH, Loitzenbauer V. 2015. Improved algorithms for
one-pair and k-pair Streett objectives. Proceedings - Symposium on Logic in Computer
Science. LICS: Logic in Computer Science vol. 2015–July, 7174888.'
mla: Chatterjee, Krishnendu, et al. “Improved Algorithms for One-Pair and k-Pair
Streett Objectives.” Proceedings - Symposium on Logic in Computer Science,
vol. 2015–July, 7174888, IEEE, 2015, doi:10.1109/LICS.2015.34.
short: K. Chatterjee, M.H. Henzinger, V. Loitzenbauer, in:, Proceedings - Symposium
on Logic in Computer Science, IEEE, 2015.
conference:
end_date: 2015-07-10
location: Kyoto, Japan
name: 'LICS: Logic in Computer Science'
start_date: 2015-07-06
date_created: 2018-12-11T11:53:19Z
date_published: 2015-07-01T00:00:00Z
date_updated: 2023-02-23T12:20:05Z
day: '01'
department:
- _id: KrCh
doi: 10.1109/LICS.2015.34
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://eprints.cs.univie.ac.at/4368/
month: '07'
oa: 1
oa_version: Submitted Version
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
publication: Proceedings - Symposium on Logic in Computer Science
publication_status: published
publisher: IEEE
publist_id: '5489'
quality_controlled: '1'
related_material:
record:
- id: '464'
relation: later_version
status: public
scopus_import: '1'
status: public
title: Improved algorithms for one-pair and k-pair Streett objectives
type: conference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
volume: 2015-July
year: '2015'
...
---
_id: '473'
abstract:
- lang: eng
text: We prove that nonlinear Gibbs measures can be obtained from the corresponding
many-body, grand-canonical, quantum Gibbs states, in a mean-field limit where
the temperature T diverges and the interaction strength behaves as 1/T. We proceed
by characterizing the interacting Gibbs state as minimizing a functional counting
the free-energy relatively to the non-interacting case. We then perform an infinite-dimensional
analogue of phase-space semiclassical analysis, using fine properties of the quantum
relative entropy, the link between quantum de Finetti measures and upper/lower
symbols in a coherent state basis, as well as Berezin-Lieb type inequalities.
Our results cover the measure built on the defocusing nonlinear Schrödinger functional
on a finite interval, as well as smoother interactions in dimensions d 2.
author:
- first_name: Mathieu
full_name: Lewin, Mathieu
last_name: Lewin
- first_name: Nam
full_name: Phan Thanh, Nam
id: 404092F4-F248-11E8-B48F-1D18A9856A87
last_name: Phan Thanh
- first_name: Nicolas
full_name: Rougerie, Nicolas
last_name: Rougerie
citation:
ama: Lewin M, Nam P, Rougerie N. Derivation of nonlinear gibbs measures from many-body
quantum mechanics. Journal de l’Ecole Polytechnique - Mathematiques. 2015;2:65-115.
doi:10.5802/jep.18
apa: Lewin, M., Nam, P., & Rougerie, N. (2015). Derivation of nonlinear gibbs
measures from many-body quantum mechanics. Journal de l’Ecole Polytechnique
- Mathematiques. Ecole Polytechnique. https://doi.org/10.5802/jep.18
chicago: Lewin, Mathieu, Phan Nam, and Nicolas Rougerie. “Derivation of Nonlinear
Gibbs Measures from Many-Body Quantum Mechanics.” Journal de l’Ecole Polytechnique
- Mathematiques. Ecole Polytechnique, 2015. https://doi.org/10.5802/jep.18.
ieee: M. Lewin, P. Nam, and N. Rougerie, “Derivation of nonlinear gibbs measures
from many-body quantum mechanics,” Journal de l’Ecole Polytechnique - Mathematiques,
vol. 2. Ecole Polytechnique, pp. 65–115, 2015.
ista: Lewin M, Nam P, Rougerie N. 2015. Derivation of nonlinear gibbs measures from
many-body quantum mechanics. Journal de l’Ecole Polytechnique - Mathematiques.
2, 65–115.
mla: Lewin, Mathieu, et al. “Derivation of Nonlinear Gibbs Measures from Many-Body
Quantum Mechanics.” Journal de l’Ecole Polytechnique - Mathematiques, vol.
2, Ecole Polytechnique, 2015, pp. 65–115, doi:10.5802/jep.18.
short: M. Lewin, P. Nam, N. Rougerie, Journal de l’Ecole Polytechnique - Mathematiques
2 (2015) 65–115.
date_created: 2018-12-11T11:46:40Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2021-01-12T08:00:52Z
day: '01'
ddc:
- '539'
department:
- _id: RoSe
doi: 10.5802/jep.18
ec_funded: 1
file:
- access_level: open_access
checksum: a40eb4016717ddc9927154798a4c164a
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:12:53Z
date_updated: 2020-07-14T12:46:35Z
file_id: '4974'
file_name: IST-2018-951-v1+1_2015_Thanh-Nam_Derivation_of.pdf
file_size: 1084254
relation: main_file
file_date_updated: 2020-07-14T12:46:35Z
has_accepted_license: '1'
intvolume: ' 2'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 65 - 115
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Journal de l'Ecole Polytechnique - Mathematiques
publication_status: published
publisher: Ecole Polytechnique
publist_id: '7344'
pubrep_id: '951'
quality_controlled: '1'
scopus_import: 1
status: public
title: Derivation of nonlinear gibbs measures from many-body quantum mechanics
tmp:
image: /image/cc_by_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nd/4.0/legalcode
name: Creative Commons Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0)
short: CC BY-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2
year: '2015'
...
---
_id: '477'
abstract:
- lang: eng
text: Dendritic cells are potent antigen-presenting cells endowed with the unique
ability to initiate adaptive immune responses upon inflammation. Inflammatory
processes are often associated with an increased production of serotonin, which
operates by activating specific receptors. However, the functional role of serotonin
receptors in regulation of dendritic cell functions is poorly understood. Here,
we demonstrate that expression of serotonin receptor 5-HT7 (5-HT7TR) as well as
its downstream effector Cdc42 is upregulated in dendritic cells upon maturation.
Although dendritic cell maturation was independent of 5-HT7TR, receptor stimulation
affected dendritic cell morphology through Cdc42-mediated signaling. In addition,
basal activity of 5-HT7TR was required for the proper expression of the chemokine
receptor CCR7, which is a key factor that controls dendritic cell migration. Consistent
with this, we observed that 5-HT7TR enhances chemotactic motility of dendritic
cells in vitro by modulating their directionality and migration velocity. Accordingly,
migration of dendritic cells in murine colon explants was abolished after pharmacological
receptor inhibition. Our results indicate that there is a crucial role for 5-HT7TR-Cdc42-mediated
signaling in the regulation of dendritic cell morphology and motility, suggesting
that 5-HT7TR could be a new target for treatment of a variety of inflammatory
and immune disorders.
author:
- first_name: Katrin
full_name: Holst, Katrin
last_name: Holst
- first_name: Daria
full_name: Guseva, Daria
last_name: Guseva
- first_name: Susann
full_name: Schindler, Susann
last_name: Schindler
- first_name: Michael K
full_name: Sixt, Michael K
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
- first_name: Armin
full_name: Braun, Armin
last_name: Braun
- first_name: Himpriya
full_name: Chopra, Himpriya
last_name: Chopra
- first_name: Oliver
full_name: Pabst, Oliver
last_name: Pabst
- first_name: Evgeni
full_name: Ponimaskin, Evgeni
last_name: Ponimaskin
citation:
ama: Holst K, Guseva D, Schindler S, et al. The serotonin receptor 5-HT7R regulates
the morphology and migratory properties of dendritic cells. Journal of Cell
Science. 2015;128(15):2866-2880. doi:10.1242/jcs.167999
apa: Holst, K., Guseva, D., Schindler, S., Sixt, M. K., Braun, A., Chopra, H., …
Ponimaskin, E. (2015). The serotonin receptor 5-HT7R regulates the morphology
and migratory properties of dendritic cells. Journal of Cell Science. Company
of Biologists. https://doi.org/10.1242/jcs.167999
chicago: Holst, Katrin, Daria Guseva, Susann Schindler, Michael K Sixt, Armin Braun,
Himpriya Chopra, Oliver Pabst, and Evgeni Ponimaskin. “The Serotonin Receptor
5-HT7R Regulates the Morphology and Migratory Properties of Dendritic Cells.”
Journal of Cell Science. Company of Biologists, 2015. https://doi.org/10.1242/jcs.167999.
ieee: K. Holst et al., “The serotonin receptor 5-HT7R regulates the morphology
and migratory properties of dendritic cells,” Journal of Cell Science,
vol. 128, no. 15. Company of Biologists, pp. 2866–2880, 2015.
ista: Holst K, Guseva D, Schindler S, Sixt MK, Braun A, Chopra H, Pabst O, Ponimaskin
E. 2015. The serotonin receptor 5-HT7R regulates the morphology and migratory
properties of dendritic cells. Journal of Cell Science. 128(15), 2866–2880.
mla: Holst, Katrin, et al. “The Serotonin Receptor 5-HT7R Regulates the Morphology
and Migratory Properties of Dendritic Cells.” Journal of Cell Science,
vol. 128, no. 15, Company of Biologists, 2015, pp. 2866–80, doi:10.1242/jcs.167999.
short: K. Holst, D. Guseva, S. Schindler, M.K. Sixt, A. Braun, H. Chopra, O. Pabst,
E. Ponimaskin, Journal of Cell Science 128 (2015) 2866–2880.
date_created: 2018-12-11T11:46:41Z
date_published: 2015-06-15T00:00:00Z
date_updated: 2021-01-12T08:00:54Z
day: '15'
department:
- _id: MiSi
doi: 10.1242/jcs.167999
intvolume: ' 128'
issue: '15'
language:
- iso: eng
month: '06'
oa_version: None
page: 2866 - 2880
publication: Journal of Cell Science
publication_status: published
publisher: Company of Biologists
publist_id: '7343'
quality_controlled: '1'
scopus_import: 1
status: public
title: The serotonin receptor 5-HT7R regulates the morphology and migratory properties
of dendritic cells
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 128
year: '2015'
...
---
_id: '523'
abstract:
- lang: eng
text: We consider two-player games played on weighted directed graphs with mean-payoff
and total-payoff objectives, two classical quantitative objectives. While for
single-dimensional games the complexity and memory bounds for both objectives
coincide, we show that in contrast to multi-dimensional mean-payoff games that
are known to be coNP-complete, multi-dimensional total-payoff games are undecidable.
We introduce conservative approximations of these objectives, where the payoff
is considered over a local finite window sliding along a play, instead of the
whole play. For single dimension, we show that (i) if the window size is polynomial,
deciding the winner takes polynomial time, and (ii) the existence of a bounded
window can be decided in NP ∩ coNP, and is at least as hard as solving mean-payoff
games. For multiple dimensions, we show that (i) the problem with fixed window
size is EXPTIME-complete, and (ii) there is no primitive-recursive algorithm to
decide the existence of a bounded window.
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Laurent
full_name: Doyen, Laurent
last_name: Doyen
- first_name: Mickael
full_name: Randour, Mickael
last_name: Randour
- first_name: Jean
full_name: Raskin, Jean
last_name: Raskin
citation:
ama: Chatterjee K, Doyen L, Randour M, Raskin J. Looking at mean-payoff and total-payoff
through windows. Information and Computation. 2015;242(6):25-52. doi:10.1016/j.ic.2015.03.010
apa: Chatterjee, K., Doyen, L., Randour, M., & Raskin, J. (2015). Looking at
mean-payoff and total-payoff through windows. Information and Computation.
Elsevier. https://doi.org/10.1016/j.ic.2015.03.010
chicago: Chatterjee, Krishnendu, Laurent Doyen, Mickael Randour, and Jean Raskin.
“Looking at Mean-Payoff and Total-Payoff through Windows.” Information and
Computation. Elsevier, 2015. https://doi.org/10.1016/j.ic.2015.03.010.
ieee: K. Chatterjee, L. Doyen, M. Randour, and J. Raskin, “Looking at mean-payoff
and total-payoff through windows,” Information and Computation, vol. 242,
no. 6. Elsevier, pp. 25–52, 2015.
ista: Chatterjee K, Doyen L, Randour M, Raskin J. 2015. Looking at mean-payoff and
total-payoff through windows. Information and Computation. 242(6), 25–52.
mla: Chatterjee, Krishnendu, et al. “Looking at Mean-Payoff and Total-Payoff through
Windows.” Information and Computation, vol. 242, no. 6, Elsevier, 2015,
pp. 25–52, doi:10.1016/j.ic.2015.03.010.
short: K. Chatterjee, L. Doyen, M. Randour, J. Raskin, Information and Computation
242 (2015) 25–52.
date_created: 2018-12-11T11:46:57Z
date_published: 2015-03-24T00:00:00Z
date_updated: 2023-02-23T10:36:02Z
day: '24'
department:
- _id: KrCh
doi: 10.1016/j.ic.2015.03.010
ec_funded: 1
intvolume: ' 242'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1302.4248
month: '03'
oa: 1
oa_version: Preprint
page: 25 - 52
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
publication: Information and Computation
publication_status: published
publisher: Elsevier
publist_id: '7296'
quality_controlled: '1'
related_material:
record:
- id: '2279'
relation: earlier_version
status: public
scopus_import: 1
status: public
title: Looking at mean-payoff and total-payoff through windows
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 242
year: '2015'
...
---
_id: '532'
abstract:
- lang: eng
text: Ethylene is a gaseous phytohormone that plays vital roles in plant growth
and development. Previous studies uncovered EIN2 as an essential signal transducer
linking ethylene perception on ER to transcriptional regulation in the nucleus
through a “cleave and shuttle” model. In this study, we report another mechanism
of EIN2-mediated ethylene signaling, whereby EIN2 imposes the translational repression
of EBF1 and EBF2 mRNA. We find that the EBF1/2 3′ UTRs mediate EIN2-directed translational
repression and identify multiple poly-uridylates (PolyU) motifs as functional
cis elements of 3′ UTRs. Furthermore, we demonstrate that ethylene induces EIN2
to associate with 3′ UTRs and target EBF1/2 mRNA to cytoplasmic processing-body
(P-body) through interacting with multiple P-body factors, including EIN5 and
PABs. Our study illustrates translational regulation as a key step in ethylene
signaling and presents mRNA 3′ UTR functioning as a “signal transducer” to sense
and relay cellular signaling in plants.
author:
- first_name: Wenyang
full_name: Li, Wenyang
last_name: Li
- first_name: Mengdi
full_name: Ma, Mengdi
last_name: Ma
- first_name: Ying
full_name: Feng, Ying
last_name: Feng
- first_name: Hongjiang
full_name: Li, Hongjiang
id: 33CA54A6-F248-11E8-B48F-1D18A9856A87
last_name: Li
orcid: 0000-0001-5039-9660
- first_name: Yichuan
full_name: Wang, Yichuan
last_name: Wang
- first_name: Yutong
full_name: Ma, Yutong
last_name: Ma
- first_name: Mingzhe
full_name: Li, Mingzhe
last_name: Li
- first_name: Fengying
full_name: An, Fengying
last_name: An
- first_name: Hongwei
full_name: Guo, Hongwei
last_name: Guo
citation:
ama: Li W, Ma M, Feng Y, et al. EIN2-directed translational regulation of ethylene
signaling in arabidopsis. Cell. 2015;163(3):670-683. doi:10.1016/j.cell.2015.09.037
apa: Li, W., Ma, M., Feng, Y., Li, H., Wang, Y., Ma, Y., … Guo, H. (2015). EIN2-directed
translational regulation of ethylene signaling in arabidopsis. Cell. Cell
Press. https://doi.org/10.1016/j.cell.2015.09.037
chicago: Li, Wenyang, Mengdi Ma, Ying Feng, Hongjiang Li, Yichuan Wang, Yutong Ma,
Mingzhe Li, Fengying An, and Hongwei Guo. “EIN2-Directed Translational Regulation
of Ethylene Signaling in Arabidopsis.” Cell. Cell Press, 2015. https://doi.org/10.1016/j.cell.2015.09.037.
ieee: W. Li et al., “EIN2-directed translational regulation of ethylene signaling
in arabidopsis,” Cell, vol. 163, no. 3. Cell Press, pp. 670–683, 2015.
ista: Li W, Ma M, Feng Y, Li H, Wang Y, Ma Y, Li M, An F, Guo H. 2015. EIN2-directed
translational regulation of ethylene signaling in arabidopsis. Cell. 163(3), 670–683.
mla: Li, Wenyang, et al. “EIN2-Directed Translational Regulation of Ethylene Signaling
in Arabidopsis.” Cell, vol. 163, no. 3, Cell Press, 2015, pp. 670–83, doi:10.1016/j.cell.2015.09.037.
short: W. Li, M. Ma, Y. Feng, H. Li, Y. Wang, Y. Ma, M. Li, F. An, H. Guo, Cell
163 (2015) 670–683.
date_created: 2018-12-11T11:47:00Z
date_published: 2015-10-22T00:00:00Z
date_updated: 2021-01-12T08:01:27Z
day: '22'
department:
- _id: JiFr
doi: 10.1016/j.cell.2015.09.037
intvolume: ' 163'
issue: '3'
language:
- iso: eng
month: '10'
oa_version: None
page: 670 - 683
publication: Cell
publication_status: published
publisher: Cell Press
publist_id: '7285'
quality_controlled: '1'
scopus_import: 1
status: public
title: EIN2-directed translational regulation of ethylene signaling in arabidopsis
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 163
year: '2015'
...
---
_id: '524'
abstract:
- lang: eng
text: 'We consider concurrent games played by two players on a finite-state graph,
where in every round the players simultaneously choose a move, and the current
state along with the joint moves determine the successor state. We study the most
fundamental objective for concurrent games, namely, mean-payoff or limit-average
objective, where a reward is associated to each transition, and the goal of player
1 is to maximize the long-run average of the rewards, and the objective of player
2 is strictly the opposite (i.e., the games are zero-sum). The path constraint
for player 1 could be qualitative, i.e., the mean-payoff is the maximal reward,
or arbitrarily close to it; or quantitative, i.e., a given threshold between the
minimal and maximal reward. We consider the computation of the almost-sure (resp.
positive) winning sets, where player 1 can ensure that the path constraint is
satisfied with probability 1 (resp. positive probability). Almost-sure winning
with qualitative constraint exactly corresponds to the question of whether there
exists a strategy to ensure that the payoff is the maximal reward of the game.
Our main results for qualitative path constraints are as follows: (1) we establish
qualitative determinacy results that show that for every state either player 1
has a strategy to ensure almost-sure (resp. positive) winning against all player-2
strategies, or player 2 has a spoiling strategy to falsify almost-sure (resp.
positive) winning against all player-1 strategies; (2) we present optimal strategy
complexity results that precisely characterize the classes of strategies required
for almost-sure and positive winning for both players; and (3) we present quadratic
time algorithms to compute the almost-sure and the positive winning sets, matching
the best known bound of the algorithms for much simpler problems (such as reachability
objectives). For quantitative constraints we show that a polynomial time solution
for the almost-sure or the positive winning set would imply a solution to a long-standing
open problem (of solving the value problem of turn-based deterministic mean-payoff
games) that is not known to be solvable in polynomial time.'
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Rasmus
full_name: Ibsen-Jensen, Rasmus
id: 3B699956-F248-11E8-B48F-1D18A9856A87
last_name: Ibsen-Jensen
orcid: 0000-0003-4783-0389
citation:
ama: Chatterjee K, Ibsen-Jensen R. Qualitative analysis of concurrent mean payoff
games. Information and Computation. 2015;242(6):2-24. doi:10.1016/j.ic.2015.03.009
apa: Chatterjee, K., & Ibsen-Jensen, R. (2015). Qualitative analysis of concurrent
mean payoff games. Information and Computation. Elsevier. https://doi.org/10.1016/j.ic.2015.03.009
chicago: Chatterjee, Krishnendu, and Rasmus Ibsen-Jensen. “Qualitative Analysis
of Concurrent Mean Payoff Games.” Information and Computation. Elsevier,
2015. https://doi.org/10.1016/j.ic.2015.03.009.
ieee: K. Chatterjee and R. Ibsen-Jensen, “Qualitative analysis of concurrent mean
payoff games,” Information and Computation, vol. 242, no. 6. Elsevier,
pp. 2–24, 2015.
ista: Chatterjee K, Ibsen-Jensen R. 2015. Qualitative analysis of concurrent mean
payoff games. Information and Computation. 242(6), 2–24.
mla: Chatterjee, Krishnendu, and Rasmus Ibsen-Jensen. “Qualitative Analysis of Concurrent
Mean Payoff Games.” Information and Computation, vol. 242, no. 6, Elsevier,
2015, pp. 2–24, doi:10.1016/j.ic.2015.03.009.
short: K. Chatterjee, R. Ibsen-Jensen, Information and Computation 242 (2015) 2–24.
date_created: 2018-12-11T11:46:57Z
date_published: 2015-10-11T00:00:00Z
date_updated: 2023-02-23T12:24:45Z
day: '11'
department:
- _id: KrCh
doi: 10.1016/j.ic.2015.03.009
external_id:
arxiv:
- '1409.5306'
intvolume: ' 242'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1409.5306
month: '10'
oa: 1
oa_version: Preprint
page: 2 - 24
publication: Information and Computation
publication_status: published
publisher: Elsevier
publist_id: '7295'
quality_controlled: '1'
related_material:
record:
- id: '5403'
relation: earlier_version
status: public
scopus_import: 1
status: public
title: Qualitative analysis of concurrent mean payoff games
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 242
year: '2015'
...
---
_id: '1481'
abstract:
- lang: eng
text: 'Simple board games, like Tic-Tac-Toe and CONNECT-4, play an important role
not only in the development of mathematical and logical skills, but also in the
emotional and social development. In this paper, we address the problem of generating
targeted starting positions for such games. This can facilitate new approaches
for bringing novice players to mastery, and also leads to discovery of interesting
game variants. We present an approach that generates starting states of varying
hardness levels for player 1 in a two-player board game, given rules of the board
game, the desired number of steps required for player 1 to win, and the expertise
levels of the two players. Our approach leverages symbolic methods and iterative
simulation to efficiently search the extremely large state space. We present experimental
results that include discovery of states of varying hardness levels for several
simple grid-based board games. The presence of such states for standard game variants
like 4×4 Tic-Tac-Toe opens up new games to be played that have never been played
as the default start state is heavily biased. '
acknowledgement: "A Technical Report of this paper is available at: \r\nhttps://repository.ist.ac.at/id/eprint/146.\r\n"
article_processing_charge: No
author:
- first_name: Umair
full_name: Ahmed, Umair
last_name: Ahmed
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Sumit
full_name: Gulwani, Sumit
last_name: Gulwani
citation:
ama: 'Ahmed U, Chatterjee K, Gulwani S. Automatic generation of alternative starting
positions for simple traditional board games. In: Proceedings of the Twenty-Ninth
AAAI Conference on Artificial Intelligence. Vol 2. AAAI Press; 2015:745-752.'
apa: 'Ahmed, U., Chatterjee, K., & Gulwani, S. (2015). Automatic generation
of alternative starting positions for simple traditional board games. In Proceedings
of the Twenty-Ninth AAAI Conference on Artificial Intelligence (Vol. 2, pp.
745–752). Austin, TX, USA: AAAI Press.'
chicago: Ahmed, Umair, Krishnendu Chatterjee, and Sumit Gulwani. “Automatic Generation
of Alternative Starting Positions for Simple Traditional Board Games.” In Proceedings
of the Twenty-Ninth AAAI Conference on Artificial Intelligence, 2:745–52.
AAAI Press, 2015.
ieee: U. Ahmed, K. Chatterjee, and S. Gulwani, “Automatic generation of alternative
starting positions for simple traditional board games,” in Proceedings of the
Twenty-Ninth AAAI Conference on Artificial Intelligence, Austin, TX, USA,
2015, vol. 2, pp. 745–752.
ista: 'Ahmed U, Chatterjee K, Gulwani S. 2015. Automatic generation of alternative
starting positions for simple traditional board games. Proceedings of the Twenty-Ninth
AAAI Conference on Artificial Intelligence. AAAI: Conference on Artificial Intelligence
vol. 2, 745–752.'
mla: Ahmed, Umair, et al. “Automatic Generation of Alternative Starting Positions
for Simple Traditional Board Games.” Proceedings of the Twenty-Ninth AAAI Conference
on Artificial Intelligence, vol. 2, AAAI Press, 2015, pp. 745–52.
short: U. Ahmed, K. Chatterjee, S. Gulwani, in:, Proceedings of the Twenty-Ninth
AAAI Conference on Artificial Intelligence, AAAI Press, 2015, pp. 745–752.
conference:
end_date: 2015-01-30
location: Austin, TX, USA
name: 'AAAI: Conference on Artificial Intelligence'
start_date: 2015-01-25
date_created: 2018-12-11T11:52:16Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2023-02-23T12:25:07Z
day: '01'
department:
- _id: KrCh
ec_funded: 1
intvolume: ' 2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.aaai.org/ocs/index.php/AAAI/AAAI15/paper/download/9523/9300
month: '01'
oa: 1
oa_version: None
page: 745 - 752
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
publication: Proceedings of the Twenty-Ninth AAAI Conference on Artificial Intelligence
publication_status: published
publisher: AAAI Press
publist_id: '5713'
quality_controlled: '1'
related_material:
record:
- id: '5410'
relation: earlier_version
status: public
scopus_import: 1
status: public
title: Automatic generation of alternative starting positions for simple traditional
board games
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2
year: '2015'
...
---
_id: '1732'
abstract:
- lang: eng
text: We consider partially observable Markov decision processes (POMDPs), that
are a standard framework for robotics applications to model uncertainties present
in the real world, with temporal logic specifications. All temporal logic specifications
in linear-time temporal logic (LTL) can be expressed as parity objectives. We
study the qualitative analysis problem for POMDPs with parity objectives that
asks whether there is a controller (policy) to ensure that the objective holds
with probability 1 (almost-surely). While the qualitative analysis of POMDPs with
parity objectives is undecidable, recent results show that when restricted to
finite-memory policies the problem is EXPTIME-complete. While the problem is intractable
in theory, we present a practical approach to solve the qualitative analysis problem.
We designed several heuristics to deal with the exponential complexity, and have
used our implementation on a number of well-known POMDP examples for robotics
applications. Our results provide the first practical approach to solve the qualitative
analysis of robot motion planning with LTL properties in the presence of uncertainty.
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Martin
full_name: Chmelik, Martin
id: 3624234E-F248-11E8-B48F-1D18A9856A87
last_name: Chmelik
- first_name: Raghav
full_name: Gupta, Raghav
last_name: Gupta
- first_name: Ayush
full_name: Kanodia, Ayush
last_name: Kanodia
citation:
ama: 'Chatterjee K, Chmelik M, Gupta R, Kanodia A. Qualitative analysis of POMDPs
with temporal logic specifications for robotics applications. In: IEEE; 2015:325-330.
doi:10.1109/ICRA.2015.7139019'
apa: 'Chatterjee, K., Chmelik, M., Gupta, R., & Kanodia, A. (2015). Qualitative
analysis of POMDPs with temporal logic specifications for robotics applications
(pp. 325–330). Presented at the ICRA: International Conference on Robotics and
Automation, Seattle, WA, United States: IEEE. https://doi.org/10.1109/ICRA.2015.7139019'
chicago: Chatterjee, Krishnendu, Martin Chmelik, Raghav Gupta, and Ayush Kanodia.
“Qualitative Analysis of POMDPs with Temporal Logic Specifications for Robotics
Applications,” 325–30. IEEE, 2015. https://doi.org/10.1109/ICRA.2015.7139019.
ieee: 'K. Chatterjee, M. Chmelik, R. Gupta, and A. Kanodia, “Qualitative analysis
of POMDPs with temporal logic specifications for robotics applications,” presented
at the ICRA: International Conference on Robotics and Automation, Seattle, WA,
United States, 2015, pp. 325–330.'
ista: 'Chatterjee K, Chmelik M, Gupta R, Kanodia A. 2015. Qualitative analysis of
POMDPs with temporal logic specifications for robotics applications. ICRA: International
Conference on Robotics and Automation, 325–330.'
mla: Chatterjee, Krishnendu, et al. Qualitative Analysis of POMDPs with Temporal
Logic Specifications for Robotics Applications. IEEE, 2015, pp. 325–30, doi:10.1109/ICRA.2015.7139019.
short: K. Chatterjee, M. Chmelik, R. Gupta, A. Kanodia, in:, IEEE, 2015, pp. 325–330.
conference:
end_date: 2015-05-30
location: Seattle, WA, United States
name: 'ICRA: International Conference on Robotics and Automation'
start_date: 2015-05-26
date_created: 2018-12-11T11:53:43Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2023-02-23T12:25:52Z
day: '01'
department:
- _id: KrCh
doi: 10.1109/ICRA.2015.7139019
ec_funded: 1
external_id:
arxiv:
- '1409.3360'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1409.3360
month: '01'
oa: 1
oa_version: Preprint
page: 325 - 330
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
publication_status: published
publisher: IEEE
publist_id: '5394'
quality_controlled: '1'
related_material:
record:
- id: '5424'
relation: earlier_version
status: public
- id: '5426'
relation: earlier_version
status: public
scopus_import: 1
status: public
title: Qualitative analysis of POMDPs with temporal logic specifications for robotics
applications
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '5431'
abstract:
- lang: eng
text: "We consider finite-state concurrent stochastic games, played by k>=2 players
for an infinite number of rounds, where in every round, each player simultaneously
and independently of the other players chooses an action, whereafter the successor
state is determined by a probability distribution given by the current state and
the chosen actions. We consider reachability objectives that given a target set
of states require that some state in the target set is visited, and the dual safety
objectives that given a target set require that only states in the target set
are visited. We are interested in the complexity of stationary strategies measured
by their patience, which is defined as the inverse of the smallest non-zero probability
employed.\r\n\r\n Our main results are as follows: We show that in two-player
zero-sum concurrent stochastic games (with reachability objective for one player
and the complementary safety objective for the other player): (i) the optimal
bound on the patience of optimal and epsilon-optimal strategies, for both players
is doubly exponential; and (ii) even in games with a single non-absorbing state
exponential (in the number of actions) patience is necessary. In general we study
the class of non-zero-sum games admitting epsilon-Nash equilibria. We show that
if there is at least one player with reachability objective, then doubly-exponential
patience is needed in general for epsilon-Nash equilibrium strategies, whereas
in contrast if all players have safety objectives, then the optimal bound on patience
for epsilon-Nash equilibrium strategies is only exponential."
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Rasmus
full_name: Ibsen-Jensen, Rasmus
id: 3B699956-F248-11E8-B48F-1D18A9856A87
last_name: Ibsen-Jensen
orcid: 0000-0003-4783-0389
- first_name: Kristoffer
full_name: Hansen, Kristoffer
last_name: Hansen
citation:
ama: Chatterjee K, Ibsen-Jensen R, Hansen K. The Patience of Concurrent Stochastic
Games with Safety and Reachability Objectives. IST Austria; 2015. doi:10.15479/AT:IST-2015-322-v1-1
apa: Chatterjee, K., Ibsen-Jensen, R., & Hansen, K. (2015). The patience
of concurrent stochastic games with safety and reachability objectives. IST
Austria. https://doi.org/10.15479/AT:IST-2015-322-v1-1
chicago: Chatterjee, Krishnendu, Rasmus Ibsen-Jensen, and Kristoffer Hansen. The
Patience of Concurrent Stochastic Games with Safety and Reachability Objectives.
IST Austria, 2015. https://doi.org/10.15479/AT:IST-2015-322-v1-1.
ieee: K. Chatterjee, R. Ibsen-Jensen, and K. Hansen, The patience of concurrent
stochastic games with safety and reachability objectives. IST Austria, 2015.
ista: Chatterjee K, Ibsen-Jensen R, Hansen K. 2015. The patience of concurrent stochastic
games with safety and reachability objectives, IST Austria, 25p.
mla: Chatterjee, Krishnendu, et al. The Patience of Concurrent Stochastic Games
with Safety and Reachability Objectives. IST Austria, 2015, doi:10.15479/AT:IST-2015-322-v1-1.
short: K. Chatterjee, R. Ibsen-Jensen, K. Hansen, The Patience of Concurrent Stochastic
Games with Safety and Reachability Objectives, IST Austria, 2015.
date_created: 2018-12-12T11:39:17Z
date_published: 2015-02-19T00:00:00Z
date_updated: 2021-01-12T08:02:13Z
day: '19'
ddc:
- '005'
- '519'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2015-322-v1-1
file:
- access_level: open_access
checksum: bfb858262c30445b8e472c40069178a2
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:31Z
date_updated: 2020-07-14T12:46:53Z
file_id: '5491'
file_name: IST-2015-322-v1+1_safetygames.pdf
file_size: 661015
relation: main_file
file_date_updated: 2020-07-14T12:46:53Z
has_accepted_license: '1'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: '25'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '322'
status: public
title: The patience of concurrent stochastic games with safety and reachability objectives
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '5434'
abstract:
- lang: eng
text: DEC-POMDPs extend POMDPs to a multi-agent setting, where several agents operate
in an uncertain environment independently to achieve a joint objective. DEC-POMDPs
have been studied with finite-horizon and infinite-horizon discounted-sum objectives,
and there exist solvers both for exact and approximate solutions. In this work
we consider Goal-DEC-POMDPs, where given a set of target states, the objective
is to ensure that the target set is reached with minimal cost. We consider the
indefinite-horizon (infinite-horizon with either discounted-sum, or undiscounted-sum,
where absorbing goal states have zero-cost) problem. We present a new method to
solve the problem that extends methods for finite-horizon DEC- POMDPs and the
RTDP-Bel approach for POMDPs. We present experimental results on several examples,
and show our approach presents promising results.
alternative_title:
- IST Austria Technical Report
author:
- first_name: '1'
full_name: Anonymous, 1
last_name: Anonymous
- first_name: '2'
full_name: Anonymous, 2
last_name: Anonymous
citation:
ama: Anonymous 1, Anonymous 2. Optimal Cost Indefinite-Horizon Reachability in
Goal DEC-POMDPs. IST Austria; 2015.
apa: Anonymous, 1, & Anonymous, 2. (2015). Optimal cost indefinite-horizon
reachability in goal DEC-POMDPs. IST Austria.
chicago: Anonymous, 1, and 2 Anonymous. Optimal Cost Indefinite-Horizon Reachability
in Goal DEC-POMDPs. IST Austria, 2015.
ieee: 1 Anonymous and 2 Anonymous, Optimal cost indefinite-horizon reachability
in goal DEC-POMDPs. IST Austria, 2015.
ista: Anonymous 1, Anonymous 2. 2015. Optimal cost indefinite-horizon reachability
in goal DEC-POMDPs, IST Austria, 16p.
mla: Anonymous, 1, and 2 Anonymous. Optimal Cost Indefinite-Horizon Reachability
in Goal DEC-POMDPs. IST Austria, 2015.
short: 1 Anonymous, 2 Anonymous, Optimal Cost Indefinite-Horizon Reachability in
Goal DEC-POMDPs, IST Austria, 2015.
date_created: 2018-12-12T11:39:18Z
date_published: 2015-02-19T00:00:00Z
date_updated: 2020-07-14T23:04:59Z
day: '19'
ddc:
- '000'
file:
- access_level: open_access
checksum: 8542fd0b10aed7811cd41077b8ccb632
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:14Z
date_updated: 2020-07-14T12:46:53Z
file_id: '5475'
file_name: IST-2015-326-v1+1_main.pdf
file_size: 378162
relation: main_file
- access_level: closed
checksum: 84c31c537bdaf7a91909f18d25d640ab
content_type: text/plain
creator: dernst
date_created: 2019-04-16T13:00:33Z
date_updated: 2020-07-14T12:46:53Z
file_id: '6317'
file_name: IST-2015-326-v1+2_authors.txt
file_size: 64
relation: main_file
file_date_updated: 2020-07-14T12:46:53Z
has_accepted_license: '1'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: '16'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '326'
status: public
title: Optimal cost indefinite-horizon reachability in goal DEC-POMDPs
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '1657'
abstract:
- lang: eng
text: 'We consider Markov decision processes (MDPs) with multiple limit-average
(or mean-payoff) objectives. There exist two different views: (i) ~the expectation
semantics, where the goal is to optimize the expected mean-payoff objective, and
(ii) ~the satisfaction semantics, where the goal is to maximize the probability
of runs such that the mean-payoff value stays above a given vector. We consider
optimization with respect to both objectives at once, thus unifying the existing
semantics. Precisely, the goal is to optimize the expectation while ensuring the
satisfaction constraint. Our problem captures the notion of optimization with
respect to strategies that are risk-averse (i.e., Ensure certain probabilistic
guarantee). Our main results are as follows: First, we present algorithms for
the decision problems, which are always polynomial in the size of the MDP. We
also show that an approximation of the Pareto curve can be computed in time polynomial
in the size of the MDP, and the approximation factor, but exponential in the number
of dimensions. Second, we present a complete characterization of the strategy
complexity (in terms of memory bounds and randomization) required to solve our
problem. '
acknowledgement: "A Technical Report of this paper is available at: https://repository.ist.ac.at/327\r\n"
alternative_title:
- LICS
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Zuzana
full_name: Komárková, Zuzana
last_name: Komárková
- first_name: Jan
full_name: Kretinsky, Jan
id: 44CEF464-F248-11E8-B48F-1D18A9856A87
last_name: Kretinsky
orcid: 0000-0002-8122-2881
citation:
ama: Chatterjee K, Komárková Z, Kretinsky J. Unifying two views on multiple mean-payoff
objectives in Markov decision processes. 2015:244-256. doi:10.1109/LICS.2015.32
apa: 'Chatterjee, K., Komárková, Z., & Kretinsky, J. (2015). Unifying two views
on multiple mean-payoff objectives in Markov decision processes. Presented at
the LICS: Logic in Computer Science, Kyoto, Japan: IEEE. https://doi.org/10.1109/LICS.2015.32'
chicago: Chatterjee, Krishnendu, Zuzana Komárková, and Jan Kretinsky. “Unifying
Two Views on Multiple Mean-Payoff Objectives in Markov Decision Processes.” LICS.
IEEE, 2015. https://doi.org/10.1109/LICS.2015.32.
ieee: K. Chatterjee, Z. Komárková, and J. Kretinsky, “Unifying two views on multiple
mean-payoff objectives in Markov decision processes.” IEEE, pp. 244–256, 2015.
ista: Chatterjee K, Komárková Z, Kretinsky J. 2015. Unifying two views on multiple
mean-payoff objectives in Markov decision processes. , 244–256.
mla: Chatterjee, Krishnendu, et al. Unifying Two Views on Multiple Mean-Payoff
Objectives in Markov Decision Processes. IEEE, 2015, pp. 244–56, doi:10.1109/LICS.2015.32.
short: K. Chatterjee, Z. Komárková, J. Kretinsky, (2015) 244–256.
conference:
end_date: 2015-07-10
location: Kyoto, Japan
name: 'LICS: Logic in Computer Science'
start_date: 2015-07-06
date_created: 2018-12-11T11:53:18Z
date_published: 2015-07-01T00:00:00Z
date_updated: 2023-02-23T12:26:16Z
day: '01'
department:
- _id: KrCh
- _id: ToHe
doi: 10.1109/LICS.2015.32
ec_funded: 1
language:
- iso: eng
month: '07'
oa_version: None
page: 244 - 256
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication_status: published
publisher: IEEE
publist_id: '5493'
quality_controlled: '1'
related_material:
record:
- id: '466'
relation: later_version
status: public
- id: '5429'
relation: earlier_version
status: public
- id: '5435'
relation: earlier_version
status: public
scopus_import: 1
series_title: LICS
status: public
title: Unifying two views on multiple mean-payoff objectives in Markov decision processes
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '1656'
abstract:
- lang: eng
text: Recently there has been a significant effort to handle quantitative properties
in formal verification and synthesis. While weighted automata over finite and
infinite words provide a natural and flexible framework to express quantitative
properties, perhaps surprisingly, some basic system properties such as average
response time cannot be expressed using weighted automata, nor in any other know
decidable formalism. In this work, we introduce nested weighted automata as a
natural extension of weighted automata which makes it possible to express important
quantitative properties such as average response time. In nested weighted automata,
a master automaton spins off and collects results from weighted slave automata,
each of which computes a quantity along a finite portion of an infinite word.
Nested weighted automata can be viewed as the quantitative analogue of monitor
automata, which are used in run-time verification. We establish an almost complete
decidability picture for the basic decision problems about nested weighted automata,
and illustrate their applicability in several domains. In particular, nested weighted
automata can be used to decide average response time properties.
acknowledgement: "This research was funded in part by the European Research Council
(ERC) under grant agreement 267989 (QUAREM), by the Austrian Science Fund (FWF)
projects S11402-N23 (RiSE), Z211-N23 (Wittgenstein Award), FWF Grant No P23499-
N23, FWF NFN Grant No S11407-N23 (RiSE), ERC Start grant (279307: Graph Games),
and Microsoft faculty fellows award.\r\nA Technical Report of the paper is available
at: \r\nhttps://repository.ist.ac.at/331/\r\n"
article_number: '7174926'
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Jan
full_name: Otop, Jan
id: 2FC5DA74-F248-11E8-B48F-1D18A9856A87
last_name: Otop
citation:
ama: 'Chatterjee K, Henzinger TA, Otop J. Nested weighted automata. In: Proceedings
- Symposium on Logic in Computer Science. Vol 2015-July. IEEE; 2015. doi:10.1109/LICS.2015.72'
apa: 'Chatterjee, K., Henzinger, T. A., & Otop, J. (2015). Nested weighted automata.
In Proceedings - Symposium on Logic in Computer Science (Vol. 2015–July).
Kyoto, Japan: IEEE. https://doi.org/10.1109/LICS.2015.72'
chicago: Chatterjee, Krishnendu, Thomas A Henzinger, and Jan Otop. “Nested Weighted
Automata.” In Proceedings - Symposium on Logic in Computer Science, Vol.
2015–July. IEEE, 2015. https://doi.org/10.1109/LICS.2015.72.
ieee: K. Chatterjee, T. A. Henzinger, and J. Otop, “Nested weighted automata,” in
Proceedings - Symposium on Logic in Computer Science, Kyoto, Japan, 2015,
vol. 2015–July.
ista: 'Chatterjee K, Henzinger TA, Otop J. 2015. Nested weighted automata. Proceedings
- Symposium on Logic in Computer Science. LICS: Logic in Computer Science vol.
2015–July, 7174926.'
mla: Chatterjee, Krishnendu, et al. “Nested Weighted Automata.” Proceedings -
Symposium on Logic in Computer Science, vol. 2015–July, 7174926, IEEE, 2015,
doi:10.1109/LICS.2015.72.
short: K. Chatterjee, T.A. Henzinger, J. Otop, in:, Proceedings - Symposium on Logic
in Computer Science, IEEE, 2015.
conference:
end_date: 2015-07-10
location: Kyoto, Japan
name: 'LICS: Logic in Computer Science'
start_date: 2015-07-06
date_created: 2018-12-11T11:53:17Z
date_published: 2015-07-31T00:00:00Z
date_updated: 2023-02-23T12:26:19Z
day: '31'
department:
- _id: KrCh
- _id: ToHe
doi: 10.1109/LICS.2015.72
ec_funded: 1
external_id:
arxiv:
- '1606.03598'
language:
- iso: eng
month: '07'
oa_version: None
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
publication: Proceedings - Symposium on Logic in Computer Science
publication_status: published
publisher: IEEE
publist_id: '5494'
quality_controlled: '1'
related_material:
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- id: '467'
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relation: earlier_version
status: public
scopus_import: 1
status: public
title: Nested weighted automata
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2015-July
year: '2015'
...
---
_id: '5429'
abstract:
- lang: eng
text: "We consider Markov decision processes (MDPs) with multiple limit-average
(or mean-payoff) objectives. \r\nThere have been two different views: (i) the
expectation semantics, where the goal is to optimize the expected mean-payoff
objective, and (ii) the satisfaction semantics, where the goal is to maximize
the probability of runs such that the mean-payoff value stays above a given vector.
\ \r\nWe consider the problem where the goal is to optimize the expectation under
the constraint that the satisfaction semantics is ensured, and thus consider a
generalization that unifies the existing semantics.\r\nOur problem captures the
notion of optimization with respect to strategies that are risk-averse (i.e.,
ensures certain probabilistic guarantee).\r\nOur main results are algorithms for
the decision problem which are always polynomial in the size of the MDP. We also
show that an approximation of the Pareto-curve can be computed in time polynomial
in the size of the MDP, and the approximation factor, but exponential in the number
of dimensions.\r\nFinally, we present a complete characterization of the strategy
complexity (in terms of memory bounds and randomization) required to solve our
problem."
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Zuzana
full_name: Komarkova, Zuzana
last_name: Komarkova
- first_name: Jan
full_name: Kretinsky, Jan
id: 44CEF464-F248-11E8-B48F-1D18A9856A87
last_name: Kretinsky
orcid: 0000-0002-8122-2881
citation:
ama: Chatterjee K, Komarkova Z, Kretinsky J. Unifying Two Views on Multiple Mean-Payoff
Objectives in Markov Decision Processes. IST Austria; 2015. doi:10.15479/AT:IST-2015-318-v1-1
apa: Chatterjee, K., Komarkova, Z., & Kretinsky, J. (2015). Unifying two
views on multiple mean-payoff objectives in Markov decision processes. IST
Austria. https://doi.org/10.15479/AT:IST-2015-318-v1-1
chicago: Chatterjee, Krishnendu, Zuzana Komarkova, and Jan Kretinsky. Unifying
Two Views on Multiple Mean-Payoff Objectives in Markov Decision Processes.
IST Austria, 2015. https://doi.org/10.15479/AT:IST-2015-318-v1-1.
ieee: K. Chatterjee, Z. Komarkova, and J. Kretinsky, Unifying two views on multiple
mean-payoff objectives in Markov decision processes. IST Austria, 2015.
ista: Chatterjee K, Komarkova Z, Kretinsky J. 2015. Unifying two views on multiple
mean-payoff objectives in Markov decision processes, IST Austria, 41p.
mla: Chatterjee, Krishnendu, et al. Unifying Two Views on Multiple Mean-Payoff
Objectives in Markov Decision Processes. IST Austria, 2015, doi:10.15479/AT:IST-2015-318-v1-1.
short: K. Chatterjee, Z. Komarkova, J. Kretinsky, Unifying Two Views on Multiple
Mean-Payoff Objectives in Markov Decision Processes, IST Austria, 2015.
date_created: 2018-12-12T11:39:17Z
date_published: 2015-01-12T00:00:00Z
date_updated: 2023-02-23T12:26:16Z
day: '12'
ddc:
- '004'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2015-318-v1-1
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checksum: e4869a584567c506349abda9c8ec7db3
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language:
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month: '01'
oa: 1
oa_version: Published Version
page: '41'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '318'
related_material:
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relation: later_version
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relation: later_version
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relation: later_version
status: public
status: public
title: Unifying two views on multiple mean-payoff objectives in Markov decision processes
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '5435'
abstract:
- lang: eng
text: "We consider Markov decision processes (MDPs) with multiple limit-average
(or mean-payoff) objectives. \r\nThere have been two different views: (i) the
expectation semantics, where the goal is to optimize the expected mean-payoff
objective, and (ii) the satisfaction semantics, where the goal is to maximize
the probability of runs such that the mean-payoff value stays above a given vector.
\ \r\nWe consider the problem where the goal is to optimize the expectation under
the constraint that the satisfaction semantics is ensured, and thus consider a
generalization that unifies the existing semantics. Our problem captures the notion
of optimization with respect to strategies that are risk-averse (i.e., ensures
certain probabilistic guarantee).\r\nOur main results are algorithms for the decision
problem which are always polynomial in the size of the MDP.\r\nWe also show that
an approximation of the Pareto-curve can be computed in time polynomial in the
size of the MDP, and the approximation factor, but exponential in the number of
dimensions. Finally, we present a complete characterization of the strategy complexity
(in terms of memory bounds and randomization) required to solve our problem."
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Zuzana
full_name: Komarkova, Zuzana
last_name: Komarkova
- first_name: Jan
full_name: Kretinsky, Jan
id: 44CEF464-F248-11E8-B48F-1D18A9856A87
last_name: Kretinsky
orcid: 0000-0002-8122-2881
citation:
ama: Chatterjee K, Komarkova Z, Kretinsky J. Unifying Two Views on Multiple Mean-Payoff
Objectives in Markov Decision Processes. IST Austria; 2015. doi:10.15479/AT:IST-2015-318-v2-1
apa: Chatterjee, K., Komarkova, Z., & Kretinsky, J. (2015). Unifying two
views on multiple mean-payoff objectives in Markov decision processes. IST
Austria. https://doi.org/10.15479/AT:IST-2015-318-v2-1
chicago: Chatterjee, Krishnendu, Zuzana Komarkova, and Jan Kretinsky. Unifying
Two Views on Multiple Mean-Payoff Objectives in Markov Decision Processes.
IST Austria, 2015. https://doi.org/10.15479/AT:IST-2015-318-v2-1.
ieee: K. Chatterjee, Z. Komarkova, and J. Kretinsky, Unifying two views on multiple
mean-payoff objectives in Markov decision processes. IST Austria, 2015.
ista: Chatterjee K, Komarkova Z, Kretinsky J. 2015. Unifying two views on multiple
mean-payoff objectives in Markov decision processes, IST Austria, 51p.
mla: Chatterjee, Krishnendu, et al. Unifying Two Views on Multiple Mean-Payoff
Objectives in Markov Decision Processes. IST Austria, 2015, doi:10.15479/AT:IST-2015-318-v2-1.
short: K. Chatterjee, Z. Komarkova, J. Kretinsky, Unifying Two Views on Multiple
Mean-Payoff Objectives in Markov Decision Processes, IST Austria, 2015.
date_created: 2018-12-12T11:39:19Z
date_published: 2015-02-23T00:00:00Z
date_updated: 2023-02-23T12:26:00Z
day: '23'
ddc:
- '004'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2015-318-v2-1
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publication_identifier:
issn:
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publication_status: published
publisher: IST Austria
pubrep_id: '327'
related_material:
record:
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relation: later_version
status: public
- id: '466'
relation: later_version
status: public
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relation: earlier_version
status: public
status: public
title: Unifying two views on multiple mean-payoff objectives in Markov decision processes
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '5436'
abstract:
- lang: eng
text: "Recently there has been a significant effort to handle quantitative properties
in formal verification and synthesis. While weighted automata over finite and
infinite words provide a natural and flexible framework to express quantitative
properties, perhaps surprisingly, some basic system properties such as average
response time cannot be expressed using weighted automata, nor in any other know
decidable formalism. In this work, we introduce nested weighted automata as a
natural extension of weighted automata which makes it possible to express important
quantitative properties such as average response time.\r\nIn nested weighted automata,
a master automaton spins off and collects results from weighted slave automata,
each of which computes a quantity along a finite portion of an infinite word.
Nested weighted automata can be viewed as the quantitative analogue of monitor
automata, which are used in run-time verification. We establish an almost complete
decidability picture for the basic decision problems about nested weighted automata,
and illustrate their applicability in several domains. In particular, nested weighted
automata can be used to decide average response time properties."
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Jan
full_name: Otop, Jan
id: 2FC5DA74-F248-11E8-B48F-1D18A9856A87
last_name: Otop
citation:
ama: Chatterjee K, Henzinger TA, Otop J. Nested Weighted Automata. IST Austria;
2015. doi:10.15479/AT:IST-2015-170-v2-2
apa: Chatterjee, K., Henzinger, T. A., & Otop, J. (2015). Nested weighted
automata. IST Austria. https://doi.org/10.15479/AT:IST-2015-170-v2-2
chicago: Chatterjee, Krishnendu, Thomas A Henzinger, and Jan Otop. Nested Weighted
Automata. IST Austria, 2015. https://doi.org/10.15479/AT:IST-2015-170-v2-2.
ieee: K. Chatterjee, T. A. Henzinger, and J. Otop, Nested weighted automata.
IST Austria, 2015.
ista: Chatterjee K, Henzinger TA, Otop J. 2015. Nested weighted automata, IST Austria,
29p.
mla: Chatterjee, Krishnendu, et al. Nested Weighted Automata. IST Austria,
2015, doi:10.15479/AT:IST-2015-170-v2-2.
short: K. Chatterjee, T.A. Henzinger, J. Otop, Nested Weighted Automata, IST Austria,
2015.
date_created: 2018-12-12T11:39:19Z
date_published: 2015-04-24T00:00:00Z
date_updated: 2023-02-23T12:25:21Z
day: '24'
ddc:
- '000'
department:
- _id: KrCh
- _id: ToHe
doi: 10.15479/AT:IST-2015-170-v2-2
file:
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checksum: 3c402f47d3669c28d04d1af405a08e3f
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page: '29'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '331'
related_material:
record:
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status: public
title: Nested weighted automata
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '1659'
abstract:
- lang: eng
text: 'The target discounted-sum problem is the following: Given a rational discount
factor 0 < λ < 1 and three rational values a, b, and t, does there exist
a finite or an infinite sequence w ε(a, b)∗ or w ε(a, b)w, such that Σ|w| i=0
w(i)λi equals t? The problem turns out to relate to many fields of mathematics
and computer science, and its decidability question is surprisingly hard to solve.
We solve the finite version of the problem, and show the hardness of the infinite
version, linking it to various areas and open problems in mathematics and computer
science: β-expansions, discounted-sum automata, piecewise affine maps, and generalizations
of the Cantor set. We provide some partial results to the infinite version, among
which are solutions to its restriction to eventually-periodic sequences and to
the cases that λ λ 1/2 or λ = 1/n, for every n ε N. We use our results for solving
some open problems on discounted-sum automata, among which are the exact-value
problem for nondeterministic automata over finite words and the universality and
inclusion problems for functional automata.'
acknowledgement: 'A technical report of the article is available at: https://research-explorer.app.ist.ac.at/record/5439'
article_processing_charge: No
author:
- first_name: Udi
full_name: Boker, Udi
id: 31E297B6-F248-11E8-B48F-1D18A9856A87
last_name: Boker
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Jan
full_name: Otop, Jan
id: 2FC5DA74-F248-11E8-B48F-1D18A9856A87
last_name: Otop
citation:
ama: 'Boker U, Henzinger TA, Otop J. The target discounted-sum problem. In: LICS.
Logic in Computer Science. IEEE; 2015:750-761. doi:10.1109/LICS.2015.74'
apa: 'Boker, U., Henzinger, T. A., & Otop, J. (2015). The target discounted-sum
problem. In LICS (pp. 750–761). Kyoto, Japan: IEEE. https://doi.org/10.1109/LICS.2015.74'
chicago: Boker, Udi, Thomas A Henzinger, and Jan Otop. “The Target Discounted-Sum
Problem.” In LICS, 750–61. Logic in Computer Science. IEEE, 2015. https://doi.org/10.1109/LICS.2015.74.
ieee: U. Boker, T. A. Henzinger, and J. Otop, “The target discounted-sum problem,”
in LICS, Kyoto, Japan, 2015, pp. 750–761.
ista: 'Boker U, Henzinger TA, Otop J. 2015. The target discounted-sum problem. LICS.
LICS: Logic in Computer ScienceLogic in Computer Science, 750–761.'
mla: Boker, Udi, et al. “The Target Discounted-Sum Problem.” LICS, IEEE,
2015, pp. 750–61, doi:10.1109/LICS.2015.74.
short: U. Boker, T.A. Henzinger, J. Otop, in:, LICS, IEEE, 2015, pp. 750–761.
conference:
end_date: 2015-07-10
location: Kyoto, Japan
name: 'LICS: Logic in Computer Science'
start_date: 2015-007-06
date_created: 2018-12-11T11:53:19Z
date_published: 2015-07-01T00:00:00Z
date_updated: 2023-02-23T12:26:27Z
day: '01'
ddc:
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department:
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doi: 10.1109/LICS.2015.74
ec_funded: 1
file:
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checksum: 6abebca9c1a620e9e103a8f9222befac
content_type: application/pdf
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file_id: '7852'
file_name: 2015_LICS_Boker.pdf
file_size: 340215
relation: main_file
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language:
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month: '07'
oa: 1
oa_version: Submitted Version
page: 750 - 761
project:
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call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
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call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
publication: LICS
publication_identifier:
eisbn:
- '978-1-4799-8875-4 '
issn:
- '1043-6871 '
publication_status: published
publisher: IEEE
publist_id: '5491'
quality_controlled: '1'
related_material:
record:
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status: public
scopus_import: 1
series_title: Logic in Computer Science
status: public
title: The target discounted-sum problem
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '1610'
abstract:
- lang: eng
text: The edit distance between two words w1, w2 is the minimal number of word operations
(letter insertions, deletions, and substitutions) necessary to transform w1 to
w2. The edit distance generalizes to languages L1,L2, where the edit distance
is the minimal number k such that for every word from L1 there exists a word in
L2 with edit distance at most k. We study the edit distance computation problem
between pushdown automata and their subclasses. The problem of computing edit
distance to pushdown automata is undecidable, and in practice, the interesting
question is to compute the edit distance from a pushdown automaton (the implementation,
a standard model for programs with recursion) to a regular language (the specification).
In this work, we present a complete picture of decidability and complexity for
deciding whether, for a given threshold k, the edit distance from a pushdown automaton
to a finite automaton is at most k.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Rasmus
full_name: Ibsen-Jensen, Rasmus
id: 3B699956-F248-11E8-B48F-1D18A9856A87
last_name: Ibsen-Jensen
orcid: 0000-0003-4783-0389
- first_name: Jan
full_name: Otop, Jan
id: 2FC5DA74-F248-11E8-B48F-1D18A9856A87
last_name: Otop
citation:
ama: 'Chatterjee K, Henzinger TA, Ibsen-Jensen R, Otop J. Edit distance for pushdown
automata. In: 42nd International Colloquium. Vol 9135. Springer Nature;
2015:121-133. doi:10.1007/978-3-662-47666-6_10'
apa: 'Chatterjee, K., Henzinger, T. A., Ibsen-Jensen, R., & Otop, J. (2015).
Edit distance for pushdown automata. In 42nd International Colloquium (Vol.
9135, pp. 121–133). Kyoto, Japan: Springer Nature. https://doi.org/10.1007/978-3-662-47666-6_10'
chicago: Chatterjee, Krishnendu, Thomas A Henzinger, Rasmus Ibsen-Jensen, and Jan
Otop. “Edit Distance for Pushdown Automata.” In 42nd International Colloquium,
9135:121–33. Springer Nature, 2015. https://doi.org/10.1007/978-3-662-47666-6_10.
ieee: K. Chatterjee, T. A. Henzinger, R. Ibsen-Jensen, and J. Otop, “Edit distance
for pushdown automata,” in 42nd International Colloquium, Kyoto, Japan,
2015, vol. 9135, no. Part II, pp. 121–133.
ista: 'Chatterjee K, Henzinger TA, Ibsen-Jensen R, Otop J. 2015. Edit distance for
pushdown automata. 42nd International Colloquium. ICALP: Automata, Languages and
Programming, LNCS, vol. 9135, 121–133.'
mla: Chatterjee, Krishnendu, et al. “Edit Distance for Pushdown Automata.” 42nd
International Colloquium, vol. 9135, no. Part II, Springer Nature, 2015, pp.
121–33, doi:10.1007/978-3-662-47666-6_10.
short: K. Chatterjee, T.A. Henzinger, R. Ibsen-Jensen, J. Otop, in:, 42nd International
Colloquium, Springer Nature, 2015, pp. 121–133.
conference:
end_date: 2015-07-10
location: Kyoto, Japan
name: 'ICALP: Automata, Languages and Programming'
start_date: 2015-07-06
date_created: 2018-12-11T11:53:01Z
date_published: 2015-07-01T00:00:00Z
date_updated: 2023-02-23T12:26:24Z
day: '01'
department:
- _id: KrCh
- _id: ToHe
doi: 10.1007/978-3-662-47666-6_10
ec_funded: 1
external_id:
arxiv:
- '1504.08259'
intvolume: ' 9135'
issue: Part II
language:
- iso: eng
main_file_link:
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url: https://arxiv.org/abs/1504.08259
month: '07'
oa: 1
oa_version: None
page: 121 - 133
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
publication: 42nd International Colloquium
publication_identifier:
isbn:
- 978-3-662-47665-9
publication_status: published
publisher: Springer Nature
publist_id: '5556'
pubrep_id: '321'
quality_controlled: '1'
related_material:
record:
- id: '465'
relation: later_version
status: public
- id: '5438'
relation: earlier_version
status: public
scopus_import: '1'
status: public
title: Edit distance for pushdown automata
type: conference
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 9135
year: '2015'
...
---
_id: '5437'
abstract:
- lang: eng
text: "We consider the core algorithmic problems related to verification of systems
with respect to three classical quantitative properties, namely, the mean-payoff
property, the ratio property, and the minimum initial credit for energy property.
\r\nThe algorithmic problem given a graph and a quantitative property asks to
compute the optimal value (the infimum value over all traces) from every node
of the graph. We consider graphs with constant treewidth, and it is well-known
that the control-flow graphs of most programs have constant treewidth. Let $n$
denote the number of nodes of a graph, $m$ the number of edges (for constant treewidth
graphs $m=O(n)$) and $W$ the largest absolute value of the weights.\r\nOur main
theoretical results are as follows.\r\nFirst, for constant treewidth graphs we
present an algorithm that approximates the mean-payoff value within a multiplicative
factor of $\\epsilon$ in time $O(n \\cdot \\log (n/\\epsilon))$ and linear space,
as compared to the classical algorithms that require quadratic time. Second, for
the ratio property we present an algorithm that for constant treewidth graphs
works in time $O(n \\cdot \\log (|a\\cdot b|))=O(n\\cdot\\log (n\\cdot W))$, when
the output is $\\frac{a}{b}$, as compared to the previously best known algorithm
with running time $O(n^2 \\cdot \\log (n\\cdot W))$. Third, for the minimum initial
credit problem we show that (i)~for general graphs the problem can be solved in
$O(n^2\\cdot m)$ time and the associated decision problem can be solved in $O(n\\cdot
m)$ time, improving the previous known $O(n^3\\cdot m\\cdot \\log (n\\cdot W))$
and $O(n^2 \\cdot m)$ bounds, respectively; and (ii)~for constant treewidth graphs
we present an algorithm that requires $O(n\\cdot \\log n)$ time, improving the
previous known $O(n^4 \\cdot \\log (n \\cdot W))$ bound.\r\nWe have implemented
some of our algorithms and show that they present a significant speedup on standard
benchmarks. "
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Rasmus
full_name: Ibsen-Jensen, Rasmus
id: 3B699956-F248-11E8-B48F-1D18A9856A87
last_name: Ibsen-Jensen
orcid: 0000-0003-4783-0389
- first_name: Andreas
full_name: Pavlogiannis, Andreas
id: 49704004-F248-11E8-B48F-1D18A9856A87
last_name: Pavlogiannis
orcid: 0000-0002-8943-0722
citation:
ama: Chatterjee K, Ibsen-Jensen R, Pavlogiannis A. Faster Algorithms for Quantitative
Verification in Constant Treewidth Graphs. IST Austria; 2015. doi:10.15479/AT:IST-2015-330-v2-1
apa: Chatterjee, K., Ibsen-Jensen, R., & Pavlogiannis, A. (2015). Faster
algorithms for quantitative verification in constant treewidth graphs. IST
Austria. https://doi.org/10.15479/AT:IST-2015-330-v2-1
chicago: Chatterjee, Krishnendu, Rasmus Ibsen-Jensen, and Andreas Pavlogiannis.
Faster Algorithms for Quantitative Verification in Constant Treewidth Graphs.
IST Austria, 2015. https://doi.org/10.15479/AT:IST-2015-330-v2-1.
ieee: K. Chatterjee, R. Ibsen-Jensen, and A. Pavlogiannis, Faster algorithms
for quantitative verification in constant treewidth graphs. IST Austria, 2015.
ista: Chatterjee K, Ibsen-Jensen R, Pavlogiannis A. 2015. Faster algorithms for
quantitative verification in constant treewidth graphs, IST Austria, 27p.
mla: Chatterjee, Krishnendu, et al. Faster Algorithms for Quantitative Verification
in Constant Treewidth Graphs. IST Austria, 2015, doi:10.15479/AT:IST-2015-330-v2-1.
short: K. Chatterjee, R. Ibsen-Jensen, A. Pavlogiannis, Faster Algorithms for Quantitative
Verification in Constant Treewidth Graphs, IST Austria, 2015.
date_created: 2018-12-12T11:39:19Z
date_published: 2015-04-27T00:00:00Z
date_updated: 2023-02-23T12:26:05Z
day: '27'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2015-330-v2-1
file:
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checksum: f5917c20f84018b362d385c000a2e123
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creator: system
date_created: 2018-12-12T11:53:12Z
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file_id: '5473'
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has_accepted_license: '1'
language:
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month: '04'
oa: 1
oa_version: Published Version
page: '27'
publication_identifier:
issn:
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publication_status: published
publisher: IST Austria
pubrep_id: '333'
related_material:
record:
- id: '1607'
relation: later_version
status: public
- id: '5430'
relation: earlier_version
status: public
status: public
title: Faster algorithms for quantitative verification in constant treewidth graphs
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '5430'
abstract:
- lang: eng
text: We consider the core algorithmic problems related to verification of systems
with respect to three classical quantitative properties, namely, the mean- payoff
property, the ratio property, and the minimum initial credit for energy property.
The algorithmic problem given a graph and a quantitative property asks to compute
the optimal value (the infimum value over all traces) from every node of the graph.
We consider graphs with constant treewidth, and it is well-known that the control-flow
graphs of most programs have constant treewidth. Let n denote the number of nodes
of a graph, m the number of edges (for constant treewidth graphs m = O ( n ) )
and W the largest absolute value of the weights. Our main theoretical results
are as follows. First, for constant treewidth graphs we present an algorithm that
approximates the mean-payoff value within a mul- tiplicative factor of ∊ in time
O ( n · log( n/∊ )) and linear space, as compared to the classical algorithms
that require quadratic time. Second, for the ratio property we present an algorithm
that for constant treewidth graphs works in time O ( n · log( | a · b · n | ))
= O ( n · log( n · W )) , when the output is a b , as compared to the previously
best known algorithm with running time O ( n 2 · log( n · W )) . Third, for the
minimum initial credit problem we show that (i) for general graphs the problem
can be solved in O ( n 2 · m ) time and the associated decision problem can be
solved in O ( n · m ) time, improving the previous known O ( n 3 · m · log( n
· W )) and O ( n 2 · m ) bounds, respectively; and (ii) for constant treewidth
graphs we present an algorithm that requires O ( n · log n ) time, improving the
previous known O ( n 4 · log( n · W )) bound. We have implemented some of our
algorithms and show that they present a significant speedup on standard benchmarks.
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Rasmus
full_name: Ibsen-Jensen, Rasmus
id: 3B699956-F248-11E8-B48F-1D18A9856A87
last_name: Ibsen-Jensen
orcid: 0000-0003-4783-0389
- first_name: Andreas
full_name: Pavlogiannis, Andreas
id: 49704004-F248-11E8-B48F-1D18A9856A87
last_name: Pavlogiannis
orcid: 0000-0002-8943-0722
citation:
ama: Chatterjee K, Ibsen-Jensen R, Pavlogiannis A. Faster Algorithms for Quantitative
Verification in Constant Treewidth Graphs. IST Austria; 2015. doi:10.15479/AT:IST-2015-319-v1-1
apa: Chatterjee, K., Ibsen-Jensen, R., & Pavlogiannis, A. (2015). Faster
algorithms for quantitative verification in constant treewidth graphs. IST
Austria. https://doi.org/10.15479/AT:IST-2015-319-v1-1
chicago: Chatterjee, Krishnendu, Rasmus Ibsen-Jensen, and Andreas Pavlogiannis.
Faster Algorithms for Quantitative Verification in Constant Treewidth Graphs.
IST Austria, 2015. https://doi.org/10.15479/AT:IST-2015-319-v1-1.
ieee: K. Chatterjee, R. Ibsen-Jensen, and A. Pavlogiannis, Faster algorithms
for quantitative verification in constant treewidth graphs. IST Austria, 2015.
ista: Chatterjee K, Ibsen-Jensen R, Pavlogiannis A. 2015. Faster algorithms for
quantitative verification in constant treewidth graphs, IST Austria, 31p.
mla: Chatterjee, Krishnendu, et al. Faster Algorithms for Quantitative Verification
in Constant Treewidth Graphs. IST Austria, 2015, doi:10.15479/AT:IST-2015-319-v1-1.
short: K. Chatterjee, R. Ibsen-Jensen, A. Pavlogiannis, Faster Algorithms for Quantitative
Verification in Constant Treewidth Graphs, IST Austria, 2015.
date_created: 2018-12-12T11:39:17Z
date_published: 2015-02-10T00:00:00Z
date_updated: 2023-02-23T12:26:22Z
day: '10'
ddc:
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department:
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oa: 1
oa_version: Published Version
page: '31'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '319'
related_material:
record:
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relation: later_version
status: public
- id: '5437'
relation: later_version
status: public
status: public
title: Faster algorithms for quantitative verification in constant treewidth graphs
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '5439'
abstract:
- lang: eng
text: 'The target discounted-sum problem is the following: Given a rational discount
factor 0 < λ < 1 and three rational values a, b, and t, does there exist a finite
or an infinite sequence w ε(a, b)∗ or w ε(a, b)w, such that Σ|w| i=0 w(i)λi equals
t? The problem turns out to relate to many fields of mathematics and computer
science, and its decidability question is surprisingly hard to solve. We solve
the finite version of the problem, and show the hardness of the infinite version,
linking it to various areas and open problems in mathematics and computer science:
β-expansions, discounted-sum automata, piecewise affine maps, and generalizations
of the Cantor set. We provide some partial results to the infinite version, among
which are solutions to its restriction to eventually-periodic sequences and to
the cases that λ λ 1/2 or λ = 1/n, for every n ε N. We use our results for solving
some open problems on discounted-sum automata, among which are the exact-value
problem for nondeterministic automata over finite words and the universality and
inclusion problems for functional automata. '
alternative_title:
- IST Austria Technical Report
author:
- first_name: Udi
full_name: Boker, Udi
id: 31E297B6-F248-11E8-B48F-1D18A9856A87
last_name: Boker
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Jan
full_name: Otop, Jan
id: 2FC5DA74-F248-11E8-B48F-1D18A9856A87
last_name: Otop
citation:
ama: Boker U, Henzinger TA, Otop J. The Target Discounted-Sum Problem. IST
Austria; 2015. doi:10.15479/AT:IST-2015-335-v1-1
apa: Boker, U., Henzinger, T. A., & Otop, J. (2015). The target discounted-sum
problem. IST Austria. https://doi.org/10.15479/AT:IST-2015-335-v1-1
chicago: Boker, Udi, Thomas A Henzinger, and Jan Otop. The Target Discounted-Sum
Problem. IST Austria, 2015. https://doi.org/10.15479/AT:IST-2015-335-v1-1.
ieee: U. Boker, T. A. Henzinger, and J. Otop, The target discounted-sum problem.
IST Austria, 2015.
ista: Boker U, Henzinger TA, Otop J. 2015. The target discounted-sum problem, IST
Austria, 20p.
mla: Boker, Udi, et al. The Target Discounted-Sum Problem. IST Austria, 2015,
doi:10.15479/AT:IST-2015-335-v1-1.
short: U. Boker, T.A. Henzinger, J. Otop, The Target Discounted-Sum Problem, IST
Austria, 2015.
date_created: 2018-12-12T11:39:20Z
date_published: 2015-05-18T00:00:00Z
date_updated: 2023-02-23T10:08:48Z
day: '18'
ddc:
- '004'
- '512'
- '513'
department:
- _id: ToHe
doi: 10.15479/AT:IST-2015-335-v1-1
file:
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oa: 1
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page: '20'
publication_identifier:
issn:
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publication_status: published
publisher: IST Austria
pubrep_id: '335'
related_material:
record:
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relation: later_version
status: public
status: public
title: The target discounted-sum problem
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '5438'
abstract:
- lang: eng
text: "The edit distance between two words w1, w2 is the minimal number of word
operations (letter insertions, deletions, and substitutions) necessary to transform
w1 to w2. The edit distance generalizes to languages L1, L2, where the edit distance
is the minimal number k such that for every word from L1 there exists a word in
L2 with edit distance at most k. We study the edit distance computation problem
between pushdown automata and their subclasses.\r\nThe problem of computing edit
distance to a pushdown automaton is undecidable, and in practice, the interesting
question is to compute the edit distance from a pushdown automaton (the implementation,
a standard model for programs with recursion) to a regular language (the specification).
In this work, we present a complete picture of decidability and complexity for
deciding whether, for a given threshold k, the edit distance from a pushdown automaton
to a finite automaton is at most k. "
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Rasmus
full_name: Ibsen-Jensen, Rasmus
id: 3B699956-F248-11E8-B48F-1D18A9856A87
last_name: Ibsen-Jensen
orcid: 0000-0003-4783-0389
- first_name: Jan
full_name: Otop, Jan
id: 2FC5DA74-F248-11E8-B48F-1D18A9856A87
last_name: Otop
citation:
ama: Chatterjee K, Henzinger TA, Ibsen-Jensen R, Otop J. Edit Distance for Pushdown
Automata. IST Austria; 2015. doi:10.15479/AT:IST-2015-334-v1-1
apa: Chatterjee, K., Henzinger, T. A., Ibsen-Jensen, R., & Otop, J. (2015).
Edit distance for pushdown automata. IST Austria. https://doi.org/10.15479/AT:IST-2015-334-v1-1
chicago: Chatterjee, Krishnendu, Thomas A Henzinger, Rasmus Ibsen-Jensen, and Jan
Otop. Edit Distance for Pushdown Automata. IST Austria, 2015. https://doi.org/10.15479/AT:IST-2015-334-v1-1.
ieee: K. Chatterjee, T. A. Henzinger, R. Ibsen-Jensen, and J. Otop, Edit distance
for pushdown automata. IST Austria, 2015.
ista: Chatterjee K, Henzinger TA, Ibsen-Jensen R, Otop J. 2015. Edit distance for
pushdown automata, IST Austria, 15p.
mla: Chatterjee, Krishnendu, et al. Edit Distance for Pushdown Automata.
IST Austria, 2015, doi:10.15479/AT:IST-2015-334-v1-1.
short: K. Chatterjee, T.A. Henzinger, R. Ibsen-Jensen, J. Otop, Edit Distance for
Pushdown Automata, IST Austria, 2015.
date_created: 2018-12-12T11:39:20Z
date_published: 2015-05-05T00:00:00Z
date_updated: 2023-02-23T12:20:08Z
day: '05'
ddc:
- '004'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2015-334-v1-1
file:
- access_level: open_access
checksum: 8a5f2d77560e552af87eb1982437a43b
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:56Z
date_updated: 2020-07-14T12:46:55Z
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file_date_updated: 2020-07-14T12:46:55Z
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language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: '15'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '334'
related_material:
record:
- id: '1610'
relation: later_version
status: public
- id: '465'
relation: later_version
status: public
status: public
title: Edit distance for pushdown automata
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '5440'
abstract:
- lang: eng
text: 'Evolution occurs in populations of reproducing individuals. The structure
of the population affects the outcome of the evolutionary process. Evolutionary
graph theory is a powerful approach to study this phenomenon. There are two graphs.
The interaction graph specifies who interacts with whom for payoff in the context
of evolution. The replacement graph specifies who competes with whom for reproduction.
The vertices of the two graphs are the same, and each vertex corresponds to an
individual of the population. The fitness (or the reproductive rate) is a non-negative
number, and depends on the payoff. A key quantity is the fixation probability
of a new mutant. It is defined as the probability that a newly introduced mutant
(on a single vertex) generates a lineage of offspring which eventually takes over
the entire population of resident individuals. The basic computational questions
are as follows: (i) the qualitative question asks whether the fixation probability
is positive; and (ii) the quantitative approximation question asks for an approximation
of the fixation probability. Our main results are as follows: First, we consider
a special case of the general problem, where the residents do not reproduce. We
show that the qualitative question is NP-complete, and the quantitative approximation
question is #P-complete, and the hardness results hold even in the special case
where the interaction and the replacement graphs coincide. Second, we show that
in general both the qualitative and the quantitative approximation questions are
PSPACE-complete. The PSPACE-hardness result for quantitative approximation holds
even when the fitness is always positive.'
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Rasmus
full_name: Ibsen-Jensen, Rasmus
id: 3B699956-F248-11E8-B48F-1D18A9856A87
last_name: Ibsen-Jensen
orcid: 0000-0003-4783-0389
- first_name: Martin
full_name: Nowak, Martin
last_name: Nowak
citation:
ama: Chatterjee K, Ibsen-Jensen R, Nowak M. The Complexity of Evolutionary Games
on Graphs. IST Austria; 2015. doi:10.15479/AT:IST-2015-323-v2-2
apa: Chatterjee, K., Ibsen-Jensen, R., & Nowak, M. (2015). The complexity
of evolutionary games on graphs. IST Austria. https://doi.org/10.15479/AT:IST-2015-323-v2-2
chicago: Chatterjee, Krishnendu, Rasmus Ibsen-Jensen, and Martin Nowak. The Complexity
of Evolutionary Games on Graphs. IST Austria, 2015. https://doi.org/10.15479/AT:IST-2015-323-v2-2.
ieee: K. Chatterjee, R. Ibsen-Jensen, and M. Nowak, The complexity of evolutionary
games on graphs. IST Austria, 2015.
ista: Chatterjee K, Ibsen-Jensen R, Nowak M. 2015. The complexity of evolutionary
games on graphs, IST Austria, 18p.
mla: Chatterjee, Krishnendu, et al. The Complexity of Evolutionary Games on Graphs.
IST Austria, 2015, doi:10.15479/AT:IST-2015-323-v2-2.
short: K. Chatterjee, R. Ibsen-Jensen, M. Nowak, The Complexity of Evolutionary
Games on Graphs, IST Austria, 2015.
date_created: 2018-12-12T11:39:21Z
date_published: 2015-06-16T00:00:00Z
date_updated: 2023-02-23T12:26:10Z
day: '16'
ddc:
- '005'
- '576'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2015-323-v2-2
file:
- access_level: open_access
checksum: 66aace7d367032af97c15e35c9be9636
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:23Z
date_updated: 2020-07-14T12:46:56Z
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has_accepted_license: '1'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: '18'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '338'
related_material:
record:
- id: '5421'
relation: earlier_version
status: public
- id: '5432'
relation: earlier_version
status: public
status: public
title: The complexity of evolutionary games on graphs
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '5432'
abstract:
- lang: eng
text: "Evolution occurs in populations of reproducing individuals. The structure
of the population affects the outcome of the evolutionary process. Evolutionary
graph theory is a powerful approach to study this phenomenon. There are two graphs.
The interaction graph specifies who interacts with whom in the context of evolution.The
replacement graph specifies who competes with whom for reproduction. \r\nThe vertices
of the two graphs are the same, and each vertex corresponds to an individual of
the population. A key quantity is the fixation probability of a new mutant. It
is defined as the probability that a newly introduced mutant (on a single vertex)
generates a lineage of offspring which eventually takes over the entire population
of resident individuals. The basic computational questions are as follows: (i)
the qualitative question asks whether the fixation probability is positive; and
(ii) the quantitative approximation question asks for an approximation of the
fixation probability. \r\nOur main results are:\r\n(1) We show that the qualitative
question is NP-complete and the quantitative approximation question is #P-hard
in the special case when the interaction and the replacement graphs coincide and
even with the restriction that the resident individuals do not reproduce (which
corresponds to an invading population taking over an empty structure).\r\n(2)
We show that in general the qualitative question is PSPACE-complete and the quantitative
approximation question is PSPACE-hard and can be solved in exponential time.\r\n"
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Rasmus
full_name: Ibsen-Jensen, Rasmus
id: 3B699956-F248-11E8-B48F-1D18A9856A87
last_name: Ibsen-Jensen
orcid: 0000-0003-4783-0389
- first_name: Martin
full_name: Nowak, Martin
last_name: Nowak
citation:
ama: Chatterjee K, Ibsen-Jensen R, Nowak M. The Complexity of Evolutionary Games
on Graphs. IST Austria; 2015. doi:10.15479/AT:IST-2015-323-v1-1
apa: Chatterjee, K., Ibsen-Jensen, R., & Nowak, M. (2015). The complexity
of evolutionary games on graphs. IST Austria. https://doi.org/10.15479/AT:IST-2015-323-v1-1
chicago: Chatterjee, Krishnendu, Rasmus Ibsen-Jensen, and Martin Nowak. The Complexity
of Evolutionary Games on Graphs. IST Austria, 2015. https://doi.org/10.15479/AT:IST-2015-323-v1-1.
ieee: K. Chatterjee, R. Ibsen-Jensen, and M. Nowak, The complexity of evolutionary
games on graphs. IST Austria, 2015.
ista: Chatterjee K, Ibsen-Jensen R, Nowak M. 2015. The complexity of evolutionary
games on graphs, IST Austria, 29p.
mla: Chatterjee, Krishnendu, et al. The Complexity of Evolutionary Games on Graphs.
IST Austria, 2015, doi:10.15479/AT:IST-2015-323-v1-1.
short: K. Chatterjee, R. Ibsen-Jensen, M. Nowak, The Complexity of Evolutionary
Games on Graphs, IST Austria, 2015.
date_created: 2018-12-12T11:39:18Z
date_published: 2015-02-19T00:00:00Z
date_updated: 2023-02-23T12:26:33Z
day: '19'
ddc:
- '005'
- '576'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2015-323-v1-1
file:
- access_level: open_access
checksum: 546c1b291d545e7b24aaaf4199dac671
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:57Z
date_updated: 2020-07-14T12:46:53Z
file_id: '5519'
file_name: IST-2015-323-v1+1_main.pdf
file_size: 576347
relation: main_file
file_date_updated: 2020-07-14T12:46:53Z
has_accepted_license: '1'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: '29'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '323'
related_material:
record:
- id: '5421'
relation: earlier_version
status: public
- id: '5440'
relation: later_version
status: public
status: public
title: The complexity of evolutionary games on graphs
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '5444'
abstract:
- lang: eng
text: A comprehensive understanding of the clonal evolution of cancer is critical
for understanding neoplasia. Genome-wide sequencing data enables evolutionary
studies at unprecedented depth. However, classical phylogenetic methods often
struggle with noisy sequencing data of impure DNA samples and fail to detect subclones
that have different evolutionary trajectories. We have developed a tool, called
Treeomics, that allows us to reconstruct the phylogeny of a cancer with commonly
available sequencing technologies. Using Bayesian inference and Integer Linear
Programming, robust phylogenies consistent with the biological processes underlying
cancer evolution were obtained for pancreatic, ovarian, and prostate cancers.
Furthermore, Treeomics correctly identified sequencing artifacts such as those
resulting from low statistical power; nearly 7% of variants were misclassified
by conventional statistical methods. These artifacts can skew phylogenies by creating
illusory tumor heterogeneity among distinct samples. Importantly, we show that
the evolutionary trees generated with Treeomics are mathematically optimal.
alternative_title:
- IST Austria Technical Report
author:
- first_name: Johannes
full_name: Reiter, Johannes
id: 4A918E98-F248-11E8-B48F-1D18A9856A87
last_name: Reiter
orcid: 0000-0002-0170-7353
- first_name: Alvin
full_name: Makohon-Moore, Alvin
last_name: Makohon-Moore
- first_name: Jeffrey
full_name: Gerold, Jeffrey
last_name: Gerold
- first_name: Ivana
full_name: Bozic, Ivana
last_name: Bozic
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Christine
full_name: Iacobuzio-Donahue, Christine
last_name: Iacobuzio-Donahue
- first_name: Bert
full_name: Vogelstein, Bert
last_name: Vogelstein
- first_name: Martin
full_name: Nowak, Martin
last_name: Nowak
citation:
ama: Reiter J, Makohon-Moore A, Gerold J, et al. Reconstructing Robust Phylogenies
of Metastatic Cancers. IST Austria; 2015. doi:10.15479/AT:IST-2015-399-v1-1
apa: Reiter, J., Makohon-Moore, A., Gerold, J., Bozic, I., Chatterjee, K., Iacobuzio-Donahue,
C., … Nowak, M. (2015). Reconstructing robust phylogenies of metastatic cancers.
IST Austria. https://doi.org/10.15479/AT:IST-2015-399-v1-1
chicago: Reiter, Johannes, Alvin Makohon-Moore, Jeffrey Gerold, Ivana Bozic, Krishnendu
Chatterjee, Christine Iacobuzio-Donahue, Bert Vogelstein, and Martin Nowak. Reconstructing
Robust Phylogenies of Metastatic Cancers. IST Austria, 2015. https://doi.org/10.15479/AT:IST-2015-399-v1-1.
ieee: J. Reiter et al., Reconstructing robust phylogenies of metastatic
cancers. IST Austria, 2015.
ista: Reiter J, Makohon-Moore A, Gerold J, Bozic I, Chatterjee K, Iacobuzio-Donahue
C, Vogelstein B, Nowak M. 2015. Reconstructing robust phylogenies of metastatic
cancers, IST Austria, 25p.
mla: Reiter, Johannes, et al. Reconstructing Robust Phylogenies of Metastatic
Cancers. IST Austria, 2015, doi:10.15479/AT:IST-2015-399-v1-1.
short: J. Reiter, A. Makohon-Moore, J. Gerold, I. Bozic, K. Chatterjee, C. Iacobuzio-Donahue,
B. Vogelstein, M. Nowak, Reconstructing Robust Phylogenies of Metastatic Cancers,
IST Austria, 2015.
date_created: 2018-12-12T11:39:22Z
date_published: 2015-12-30T00:00:00Z
date_updated: 2020-07-14T23:05:07Z
day: '30'
ddc:
- '000'
- '576'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2015-399-v1-1
file:
- access_level: open_access
checksum: c47d33bdda06181753c0af36f16e7b5d
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:24Z
date_updated: 2020-07-14T12:46:58Z
file_id: '5485'
file_name: IST-2015-399-v1+1_treeomics.pdf
file_size: 3533200
relation: main_file
file_date_updated: 2020-07-14T12:46:58Z
has_accepted_license: '1'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: '25'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '399'
status: public
title: Reconstructing robust phylogenies of metastatic cancers
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '5443'
abstract:
- lang: eng
text: POMDPs are standard models for probabilistic planning problems, where an agent
interacts with an uncertain environment. We study the problem of almost-sure reachability,
where given a set of target states, the question is to decide whether there is
a policy to ensure that the target set is reached with probability 1 (almost-surely).
While in general the problem is EXPTIME-complete, in many practical cases policies
with a small amount of memory suffice. Moreover, the existing solution to the
problem is explicit, which first requires to construct explicitly an exponential
reduction to a belief-support MDP. In this work, we first study the existence
of observation-stationary strategies, which is NP-complete, and then small-memory
strategies. We present a symbolic algorithm by an efficient encoding to SAT and
using a SAT solver for the problem. We report experimental results demonstrating
the scalability of our symbolic (SAT-based) approach.
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Martin
full_name: Chmelik, Martin
id: 3624234E-F248-11E8-B48F-1D18A9856A87
last_name: Chmelik
- first_name: Jessica
full_name: Davies, Jessica
id: 378E0060-F248-11E8-B48F-1D18A9856A87
last_name: Davies
citation:
ama: Chatterjee K, Chmelik M, Davies J. A Symbolic SAT-Based Algorithm for Almost-Sure
Reachability with Small Strategies in POMDPs. IST Austria; 2015. doi:10.15479/AT:IST-2015-325-v2-1
apa: Chatterjee, K., Chmelik, M., & Davies, J. (2015). A symbolic SAT-based
algorithm for almost-sure reachability with small strategies in POMDPs. IST
Austria. https://doi.org/10.15479/AT:IST-2015-325-v2-1
chicago: Chatterjee, Krishnendu, Martin Chmelik, and Jessica Davies. A Symbolic
SAT-Based Algorithm for Almost-Sure Reachability with Small Strategies in POMDPs.
IST Austria, 2015. https://doi.org/10.15479/AT:IST-2015-325-v2-1.
ieee: K. Chatterjee, M. Chmelik, and J. Davies, A symbolic SAT-based algorithm
for almost-sure reachability with small strategies in POMDPs. IST Austria,
2015.
ista: Chatterjee K, Chmelik M, Davies J. 2015. A symbolic SAT-based algorithm for
almost-sure reachability with small strategies in POMDPs, IST Austria, 23p.
mla: Chatterjee, Krishnendu, et al. A Symbolic SAT-Based Algorithm for Almost-Sure
Reachability with Small Strategies in POMDPs. IST Austria, 2015, doi:10.15479/AT:IST-2015-325-v2-1.
short: K. Chatterjee, M. Chmelik, J. Davies, A Symbolic SAT-Based Algorithm for
Almost-Sure Reachability with Small Strategies in POMDPs, IST Austria, 2015.
date_created: 2018-12-12T11:39:22Z
date_published: 2015-11-06T00:00:00Z
date_updated: 2023-02-21T16:24:05Z
day: '06'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2015-325-v2-1
file:
- access_level: open_access
checksum: f0fa31ad8161ed655137e94012123ef9
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:05Z
date_updated: 2020-07-14T12:46:57Z
file_id: '5466'
file_name: IST-2015-325-v2+1_main.pdf
file_size: 412379
relation: main_file
file_date_updated: 2020-07-14T12:46:57Z
has_accepted_license: '1'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: '23'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '362'
related_material:
record:
- id: '1166'
relation: later_version
status: public
status: public
title: A symbolic SAT-based algorithm for almost-sure reachability with small strategies
in POMDPs
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '1511'
abstract:
- lang: eng
text: 'The fact that the complete graph K_5 does not embed in the plane has been
generalized in two independent directions. On the one hand, the solution of the
classical Heawood problem for graphs on surfaces established that the complete
graph K_n embeds in a closed surface M if and only if (n-3)(n-4) is at most 6b_1(M),
where b_1(M) is the first Z_2-Betti number of M. On the other hand, Van Kampen
and Flores proved that the k-skeleton of the n-dimensional simplex (the higher-dimensional
analogue of K_{n+1}) embeds in R^{2k} if and only if n is less or equal to 2k+2.
Two decades ago, Kuhnel conjectured that the k-skeleton of the n-simplex embeds
in a compact, (k-1)-connected 2k-manifold with kth Z_2-Betti number b_k only if
the following generalized Heawood inequality holds: binom{n-k-1}{k+1} is at most
binom{2k+1}{k+1} b_k. This is a common generalization of the case of graphs on
surfaces as well as the Van Kampen--Flores theorem. In the spirit of Kuhnel''s
conjecture, we prove that if the k-skeleton of the n-simplex embeds in a 2k-manifold
with kth Z_2-Betti number b_k, then n is at most 2b_k binom{2k+2}{k} + 2k + 5.
This bound is weaker than the generalized Heawood inequality, but does not require
the assumption that M is (k-1)-connected. Our proof uses a result of Volovikov
about maps that satisfy a certain homological triviality condition.'
acknowledgement: "The work by Z. P. was partially supported by the Charles University
Grant SVV-2014-260103. The\r\nwork by Z. P. and M. T. was partially supported by
the project CE-ITI (GACR P202/12/G061) of\r\nthe Czech Science Foundation and by
the ERC Advanced Grant No. 267165. Part of the research\r\nwork of M. T. was conducted
at IST Austria, supported by an IST Fellowship. The work by U.W.\r\nwas partially
supported by the Swiss National Science Foundation (grants SNSF-200020-138230 and\r\nSNSF-PP00P2-138948)."
alternative_title:
- LIPIcs
author:
- first_name: Xavier
full_name: Goaoc, Xavier
last_name: Goaoc
- first_name: Isaac
full_name: Mabillard, Isaac
id: 32BF9DAA-F248-11E8-B48F-1D18A9856A87
last_name: Mabillard
- first_name: Pavel
full_name: Paták, Pavel
last_name: Paták
- first_name: Zuzana
full_name: Patakova, Zuzana
id: 48B57058-F248-11E8-B48F-1D18A9856A87
last_name: Patakova
orcid: 0000-0002-3975-1683
- first_name: Martin
full_name: Tancer, Martin
id: 38AC689C-F248-11E8-B48F-1D18A9856A87
last_name: Tancer
orcid: 0000-0002-1191-6714
- first_name: Uli
full_name: Wagner, Uli
id: 36690CA2-F248-11E8-B48F-1D18A9856A87
last_name: Wagner
orcid: 0000-0002-1494-0568
citation:
ama: 'Goaoc X, Mabillard I, Paták P, Patakova Z, Tancer M, Wagner U. On generalized
Heawood inequalities for manifolds: A Van Kampen–Flores-type nonembeddability
result. In: Vol 34. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2015:476-490.
doi:10.4230/LIPIcs.SOCG.2015.476'
apa: 'Goaoc, X., Mabillard, I., Paták, P., Patakova, Z., Tancer, M., & Wagner,
U. (2015). On generalized Heawood inequalities for manifolds: A Van Kampen–Flores-type
nonembeddability result (Vol. 34, pp. 476–490). Presented at the SoCG: Symposium
on Computational Geometry, Eindhoven, Netherlands: Schloss Dagstuhl - Leibniz-Zentrum
für Informatik. https://doi.org/10.4230/LIPIcs.SOCG.2015.476'
chicago: 'Goaoc, Xavier, Isaac Mabillard, Pavel Paták, Zuzana Patakova, Martin Tancer,
and Uli Wagner. “On Generalized Heawood Inequalities for Manifolds: A Van Kampen–Flores-Type
Nonembeddability Result,” 34:476–90. Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
2015. https://doi.org/10.4230/LIPIcs.SOCG.2015.476.'
ieee: 'X. Goaoc, I. Mabillard, P. Paták, Z. Patakova, M. Tancer, and U. Wagner,
“On generalized Heawood inequalities for manifolds: A Van Kampen–Flores-type nonembeddability
result,” presented at the SoCG: Symposium on Computational Geometry, Eindhoven,
Netherlands, 2015, vol. 34, pp. 476–490.'
ista: 'Goaoc X, Mabillard I, Paták P, Patakova Z, Tancer M, Wagner U. 2015. On generalized
Heawood inequalities for manifolds: A Van Kampen–Flores-type nonembeddability
result. SoCG: Symposium on Computational Geometry, LIPIcs, vol. 34, 476–490.'
mla: 'Goaoc, Xavier, et al. On Generalized Heawood Inequalities for Manifolds:
A Van Kampen–Flores-Type Nonembeddability Result. Vol. 34, Schloss Dagstuhl
- Leibniz-Zentrum für Informatik, 2015, pp. 476–90, doi:10.4230/LIPIcs.SOCG.2015.476.'
short: X. Goaoc, I. Mabillard, P. Paták, Z. Patakova, M. Tancer, U. Wagner, in:,
Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2015, pp. 476–490.
conference:
end_date: 2015-06-25
location: Eindhoven, Netherlands
name: 'SoCG: Symposium on Computational Geometry'
start_date: 2015-06-22
date_created: 2018-12-11T11:52:27Z
date_published: 2015-06-11T00:00:00Z
date_updated: 2023-02-23T12:38:00Z
day: '11'
ddc:
- '510'
department:
- _id: UlWa
doi: 10.4230/LIPIcs.SOCG.2015.476
ec_funded: 1
file:
- access_level: open_access
checksum: 0945811875351796324189312ca29e9e
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:11:18Z
date_updated: 2020-07-14T12:44:59Z
file_id: '4871'
file_name: IST-2016-502-v1+1_42.pdf
file_size: 636735
relation: main_file
file_date_updated: 2020-07-14T12:44:59Z
has_accepted_license: '1'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 476 - 490
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '5666'
pubrep_id: '502'
quality_controlled: '1'
related_material:
record:
- id: '610'
relation: later_version
status: public
scopus_import: 1
status: public
title: 'On generalized Heawood inequalities for manifolds: A Van Kampen–Flores-type
nonembeddability result'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: '34 '
year: '2015'
...
---
_id: '1637'
abstract:
- lang: eng
text: An instance of the Valued Constraint Satisfaction Problem (VCSP) is given
by a finite set of variables, a finite domain of labels, and a sum of functions,
each function depending on a subset of the variables. Each function can take finite
values specifying costs of assignments of labels to its variables or the infinite
value, which indicates an infeasible assignment. The goal is to find an assignment
of labels to the variables that minimizes the sum. We study, assuming that P ≠
NP, how the complexity of this very general problem depends on the set of functions
allowed in the instances, the so-called constraint language. The case when all
allowed functions take values in {0, ∞} corresponds to ordinary CSPs, where one
deals only with the feasibility issue and there is no optimization. This case
is the subject of the Algebraic CSP Dichotomy Conjecture predicting for which
constraint languages CSPs are tractable (i.e. solvable in polynomial time) and
for which NP-hard. The case when all allowed functions take only finite values
corresponds to finite-valued CSP, where the feasibility aspect is trivial and
one deals only with the optimization issue. The complexity of finite-valued CSPs
was fully classified by Thapper and Zivny. An algebraic necessary condition for
tractability of a general-valued CSP with a fixed constraint language was recently
given by Kozik and Ochremiak. As our main result, we prove that if a constraint
language satisfies this algebraic necessary condition, and the feasibility CSP
(i.e. the problem of deciding whether a given instance has a feasible solution)
corresponding to the VCSP with this language is tractable, then the VCSP is tractable.
The algorithm is a simple combination of the assumed algorithm for the feasibility
CSP and the standard LP relaxation. As a corollary, we obtain that a dichotomy
for ordinary CSPs would imply a dichotomy for general-valued CSPs.
alternative_title:
- 56th Annual Symposium on Foundations of Computer Science
author:
- first_name: Vladimir
full_name: Kolmogorov, Vladimir
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
- first_name: Andrei
full_name: Krokhin, Andrei
last_name: Krokhin
- first_name: Michal
full_name: Rolinek, Michal
id: 3CB3BC06-F248-11E8-B48F-1D18A9856A87
last_name: Rolinek
citation:
ama: 'Kolmogorov V, Krokhin A, Rolinek M. The complexity of general-valued CSPs.
In: IEEE; 2015:1246-1258. doi:10.1109/FOCS.2015.80'
apa: 'Kolmogorov, V., Krokhin, A., & Rolinek, M. (2015). The complexity of general-valued
CSPs (pp. 1246–1258). Presented at the FOCS: Foundations of Computer Science,
Berkeley, CA, United States: IEEE. https://doi.org/10.1109/FOCS.2015.80'
chicago: Kolmogorov, Vladimir, Andrei Krokhin, and Michal Rolinek. “The Complexity
of General-Valued CSPs,” 1246–58. IEEE, 2015. https://doi.org/10.1109/FOCS.2015.80.
ieee: 'V. Kolmogorov, A. Krokhin, and M. Rolinek, “The complexity of general-valued
CSPs,” presented at the FOCS: Foundations of Computer Science, Berkeley, CA, United
States, 2015, pp. 1246–1258.'
ista: 'Kolmogorov V, Krokhin A, Rolinek M. 2015. The complexity of general-valued
CSPs. FOCS: Foundations of Computer Science, 56th Annual Symposium on Foundations
of Computer Science, , 1246–1258.'
mla: Kolmogorov, Vladimir, et al. The Complexity of General-Valued CSPs.
IEEE, 2015, pp. 1246–58, doi:10.1109/FOCS.2015.80.
short: V. Kolmogorov, A. Krokhin, M. Rolinek, in:, IEEE, 2015, pp. 1246–1258.
conference:
end_date: 2015-10-20
location: Berkeley, CA, United States
name: 'FOCS: Foundations of Computer Science'
start_date: 2015-10-18
date_created: 2018-12-11T11:53:10Z
date_published: 2015-12-01T00:00:00Z
date_updated: 2023-02-23T12:44:26Z
day: '01'
department:
- _id: VlKo
doi: 10.1109/FOCS.2015.80
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://arxiv.org/abs/1502.07327
month: '12'
oa: 1
oa_version: Preprint
page: 1246 - 1258
project:
- _id: 25FBA906-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '616160'
name: 'Discrete Optimization in Computer Vision: Theory and Practice'
publication_status: published
publisher: IEEE
publist_id: '5518'
quality_controlled: '1'
related_material:
record:
- id: '644'
relation: other
status: public
scopus_import: 1
status: public
title: The complexity of general-valued CSPs
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '802'
abstract:
- lang: eng
text: Glycoinositolphosphoceramides (GIPCs) are complex sphingolipids present at
the plasma membrane of various eukaryotes with the important exception of mammals.
In fungi, these glycosphingolipids commonly contain an alpha-mannose residue (Man)
linked at position 2 of the inositol. However, several pathogenic fungi additionally
synthesize zwitterionic GIPCs carrying an alpha-glucosamine residue (GlcN) at
this position. In the human pathogen Aspergillus fumigatus, the GlcNalpha1,2IPC
core (where IPC is inositolphosphoceramide) is elongated to Manalpha1,3Manalpha1,6GlcNalpha1,2IPC,
which is the most abundant GIPC synthesized by this fungus. In this study, we
identified an A. fumigatus N-acetylglucosaminyltransferase, named GntA, and demonstrate
its involvement in the initiation of zwitterionic GIPC biosynthesis. Targeted
deletion of the gene encoding GntA in A. fumigatus resulted in complete absence
of zwitterionic GIPC; a phenotype that could be reverted by episomal expression
of GntA in the mutant. The N-acetylhexosaminyltransferase activity of GntA was
substantiated by production of N-acetylhexosamine-IPC in the yeast Saccharomyces
cerevisiae upon GntA expression. Using an in vitro assay, GntA was furthermore
shown to use UDP-N-acetylglucosamine as donor substrate to generate a glycolipid
product resistant to saponification and to digestion by phosphatidylinositol-phospholipase
C as expected for GlcNAcalpha1,2IPC. Finally, as the enzymes involved in mannosylation
of IPC, GntA was localized to the Golgi apparatus, the site of IPC synthesis.
author:
- first_name: Jakob
full_name: Engel, Jakob
last_name: Engel
- first_name: Philipp S
full_name: Schmalhorst, Philipp S
id: 309D50DA-F248-11E8-B48F-1D18A9856A87
last_name: Schmalhorst
orcid: 0000-0002-5795-0133
- first_name: Anke
full_name: Kruger, Anke
last_name: Kruger
- first_name: Christina
full_name: Muller, Christina
last_name: Muller
- first_name: Falk
full_name: Buettner, Falk
last_name: Buettner
- first_name: Françoise
full_name: Routier, Françoise
last_name: Routier
citation:
ama: Engel J, Schmalhorst PS, Kruger A, Muller C, Buettner F, Routier F. Characterization
of an N-acetylglucosaminyltransferase involved in Aspergillus fumigatus zwitterionic
glycoinositolphosphoceramide biosynthesis. Glycobiology. 2015;25(12):1423-1430.
doi:10.1093/glycob/cwv059
apa: Engel, J., Schmalhorst, P. S., Kruger, A., Muller, C., Buettner, F., &
Routier, F. (2015). Characterization of an N-acetylglucosaminyltransferase involved
in Aspergillus fumigatus zwitterionic glycoinositolphosphoceramide biosynthesis.
Glycobiology. Oxford University Press. https://doi.org/10.1093/glycob/cwv059
chicago: Engel, Jakob, Philipp S Schmalhorst, Anke Kruger, Christina Muller, Falk
Buettner, and Françoise Routier. “Characterization of an N-Acetylglucosaminyltransferase
Involved in Aspergillus Fumigatus Zwitterionic Glycoinositolphosphoceramide Biosynthesis.”
Glycobiology. Oxford University Press, 2015. https://doi.org/10.1093/glycob/cwv059.
ieee: J. Engel, P. S. Schmalhorst, A. Kruger, C. Muller, F. Buettner, and F. Routier,
“Characterization of an N-acetylglucosaminyltransferase involved in Aspergillus
fumigatus zwitterionic glycoinositolphosphoceramide biosynthesis,” Glycobiology,
vol. 25, no. 12. Oxford University Press, pp. 1423–1430, 2015.
ista: Engel J, Schmalhorst PS, Kruger A, Muller C, Buettner F, Routier F. 2015.
Characterization of an N-acetylglucosaminyltransferase involved in Aspergillus
fumigatus zwitterionic glycoinositolphosphoceramide biosynthesis. Glycobiology.
25(12), 1423–1430.
mla: Engel, Jakob, et al. “Characterization of an N-Acetylglucosaminyltransferase
Involved in Aspergillus Fumigatus Zwitterionic Glycoinositolphosphoceramide Biosynthesis.”
Glycobiology, vol. 25, no. 12, Oxford University Press, 2015, pp. 1423–30,
doi:10.1093/glycob/cwv059.
short: J. Engel, P.S. Schmalhorst, A. Kruger, C. Muller, F. Buettner, F. Routier,
Glycobiology 25 (2015) 1423–1430.
date_created: 2018-12-11T11:48:35Z
date_published: 2015-12-01T00:00:00Z
date_updated: 2021-01-12T08:16:33Z
day: '01'
department:
- _id: CaHe
doi: 10.1093/glycob/cwv059
external_id:
pmid:
- '26306635'
intvolume: ' 25'
issue: '12'
language:
- iso: eng
month: '12'
oa_version: None
page: 1423 - 1430
pmid: 1
publication: Glycobiology
publication_status: published
publisher: Oxford University Press
publist_id: '6851'
quality_controlled: '1'
scopus_import: 1
status: public
title: Characterization of an N-acetylglucosaminyltransferase involved in Aspergillus
fumigatus zwitterionic glycoinositolphosphoceramide biosynthesis
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 25
year: '2015'
...
---
_id: '9711'
article_processing_charge: No
author:
- first_name: Guillaume
full_name: Chevereau, Guillaume
id: 424D78A0-F248-11E8-B48F-1D18A9856A87
last_name: Chevereau
- first_name: Marta
full_name: Lukacisinova, Marta
id: 4342E402-F248-11E8-B48F-1D18A9856A87
last_name: Lukacisinova
orcid: 0000-0002-2519-8004
- first_name: Tugce
full_name: Batur, Tugce
last_name: Batur
- first_name: Aysegul
full_name: Guvenek, Aysegul
last_name: Guvenek
- first_name: Dilay Hazal
full_name: Ayhan, Dilay Hazal
last_name: Ayhan
- first_name: Erdal
full_name: Toprak, Erdal
last_name: Toprak
- first_name: Mark Tobias
full_name: Bollenbach, Mark Tobias
id: 3E6DB97A-F248-11E8-B48F-1D18A9856A87
last_name: Bollenbach
orcid: 0000-0003-4398-476X
citation:
ama: Chevereau G, Lukacisinova M, Batur T, et al. Excel file containing the raw
data for all figures. 2015. doi:10.1371/journal.pbio.1002299.s001
apa: Chevereau, G., Lukacisinova, M., Batur, T., Guvenek, A., Ayhan, D. H., Toprak,
E., & Bollenbach, M. T. (2015). Excel file containing the raw data for all
figures. Public Library of Science. https://doi.org/10.1371/journal.pbio.1002299.s001
chicago: Chevereau, Guillaume, Marta Lukacisinova, Tugce Batur, Aysegul Guvenek,
Dilay Hazal Ayhan, Erdal Toprak, and Mark Tobias Bollenbach. “Excel File Containing
the Raw Data for All Figures.” Public Library of Science, 2015. https://doi.org/10.1371/journal.pbio.1002299.s001.
ieee: G. Chevereau et al., “Excel file containing the raw data for all figures.”
Public Library of Science, 2015.
ista: Chevereau G, Lukacisinova M, Batur T, Guvenek A, Ayhan DH, Toprak E, Bollenbach
MT. 2015. Excel file containing the raw data for all figures, Public Library of
Science, 10.1371/journal.pbio.1002299.s001.
mla: Chevereau, Guillaume, et al. Excel File Containing the Raw Data for All
Figures. Public Library of Science, 2015, doi:10.1371/journal.pbio.1002299.s001.
short: G. Chevereau, M. Lukacisinova, T. Batur, A. Guvenek, D.H. Ayhan, E. Toprak,
M.T. Bollenbach, (2015).
date_created: 2021-07-23T11:53:50Z
date_published: 2015-11-18T00:00:00Z
date_updated: 2023-02-23T10:07:02Z
day: '18'
department:
- _id: ToBo
doi: 10.1371/journal.pbio.1002299.s001
month: '11'
oa_version: Published Version
publisher: Public Library of Science
related_material:
record:
- id: '1619'
relation: used_in_publication
status: public
status: public
title: Excel file containing the raw data for all figures
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2015'
...
---
_id: '1855'
abstract:
- lang: eng
text: 'Summary: Declining populations of bee pollinators are a cause of concern,
with major repercussions for biodiversity loss and food security. RNA viruses
associated with honeybees represent a potential threat to other insect pollinators,
but the extent of this threat is poorly understood. This study aims to attain
a detailed understanding of the current and ongoing risk of emerging infectious
disease (EID) transmission between managed and wild pollinator species across
a wide range of RNA viruses. Within a structured large-scale national survey across
26 independent sites, we quantify the prevalence and pathogen loads of multiple
RNA viruses in co-occurring managed honeybee (Apis mellifera) and wild bumblebee
(Bombus spp.) populations. We then construct models that compare virus prevalence
between wild and managed pollinators. Multiple RNA viruses associated with honeybees
are widespread in sympatric wild bumblebee populations. Virus prevalence in honeybees
is a significant predictor of virus prevalence in bumblebees, but we remain cautious
in speculating over the principle direction of pathogen transmission. We demonstrate
species-specific differences in prevalence, indicating significant variation in
disease susceptibility or tolerance. Pathogen loads within individual bumblebees
may be high and in the case of at least one RNA virus, prevalence is higher in
wild bumblebees than in managed honeybee populations. Our findings indicate widespread
transmission of RNA viruses between managed and wild bee pollinators, pointing
to an interconnected network of potential disease pressures within and among pollinator
species. In the context of the biodiversity crisis, our study emphasizes the importance
of targeting a wide range of pathogens and defining host associations when considering
potential drivers of population decline.'
acknowledgement: We thank J.R. de Miranda, L. De Smet and D. de Graaf for supplying
qRT-PCR and MLPA positive controls, respectively, in the form of plasmids. This
work was supported by the Insect Pollinators Initiative (IPI grants BB/1000100/1
and BB/I000151/1). The IPI is funded jointly by the Biotechnology and Biological
Sciences Research Council, the Department for Environment, Food and Rural Affairs,
the Natural Environment Research Council, The Scottish Government and The Wellcome
Trust, under the Living with Environmental Change Partnership.
article_processing_charge: No
article_type: original
author:
- first_name: Dino
full_name: Mcmahon, Dino
last_name: Mcmahon
- first_name: Matthias
full_name: Fürst, Matthias
id: 393B1196-F248-11E8-B48F-1D18A9856A87
last_name: Fürst
orcid: 0000-0002-3712-925X
- first_name: Jesicca
full_name: Caspar, Jesicca
last_name: Caspar
- first_name: Panagiotis
full_name: Theodorou, Panagiotis
last_name: Theodorou
- first_name: Mark
full_name: Brown, Mark
last_name: Brown
- first_name: Robert
full_name: Paxton, Robert
last_name: Paxton
citation:
ama: 'Mcmahon D, Fürst M, Caspar J, Theodorou P, Brown M, Paxton R. A sting in the
spit: Widespread cross-infection of multiple RNA viruses across wild and managed
bees. Journal of Animal Ecology. 2015;84(3):615-624. doi:10.1111/1365-2656.12345'
apa: 'Mcmahon, D., Fürst, M., Caspar, J., Theodorou, P., Brown, M., & Paxton,
R. (2015). A sting in the spit: Widespread cross-infection of multiple RNA viruses
across wild and managed bees. Journal of Animal Ecology. Wiley. https://doi.org/10.1111/1365-2656.12345'
chicago: 'Mcmahon, Dino, Matthias Fürst, Jesicca Caspar, Panagiotis Theodorou, Mark
Brown, and Robert Paxton. “A Sting in the Spit: Widespread Cross-Infection of
Multiple RNA Viruses across Wild and Managed Bees.” Journal of Animal Ecology.
Wiley, 2015. https://doi.org/10.1111/1365-2656.12345.'
ieee: 'D. Mcmahon, M. Fürst, J. Caspar, P. Theodorou, M. Brown, and R. Paxton, “A
sting in the spit: Widespread cross-infection of multiple RNA viruses across wild
and managed bees,” Journal of Animal Ecology, vol. 84, no. 3. Wiley, pp.
615–624, 2015.'
ista: 'Mcmahon D, Fürst M, Caspar J, Theodorou P, Brown M, Paxton R. 2015. A sting
in the spit: Widespread cross-infection of multiple RNA viruses across wild and
managed bees. Journal of Animal Ecology. 84(3), 615–624.'
mla: 'Mcmahon, Dino, et al. “A Sting in the Spit: Widespread Cross-Infection of
Multiple RNA Viruses across Wild and Managed Bees.” Journal of Animal Ecology,
vol. 84, no. 3, Wiley, 2015, pp. 615–24, doi:10.1111/1365-2656.12345.'
short: D. Mcmahon, M. Fürst, J. Caspar, P. Theodorou, M. Brown, R. Paxton, Journal
of Animal Ecology 84 (2015) 615–624.
date_created: 2018-12-11T11:54:23Z
date_published: 2015-03-03T00:00:00Z
date_updated: 2023-02-23T14:06:09Z
day: '03'
ddc:
- '570'
department:
- _id: SyCr
doi: 10.1111/1365-2656.12345
external_id:
pmid:
- '25646973'
file:
- access_level: open_access
checksum: 542a0b9b07e78050a81b35f26f0b82da
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:18:29Z
date_updated: 2020-07-14T12:45:19Z
file_id: '5350'
file_name: IST-2016-460-v1+1_McMahon_et_al-2015-Journal_of_Animal_Ecology.pdf
file_size: 1823045
relation: main_file
file_date_updated: 2020-07-14T12:45:19Z
has_accepted_license: '1'
intvolume: ' 84'
issue: '3'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 615 - 624
pmid: 1
publication: Journal of Animal Ecology
publication_status: published
publisher: Wiley
publist_id: '5245'
pubrep_id: '460'
quality_controlled: '1'
related_material:
record:
- id: '9720'
relation: research_data
status: public
scopus_import: '1'
status: public
title: 'A sting in the spit: Widespread cross-infection of multiple RNA viruses across
wild and managed bees'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
volume: 84
year: '2015'
...
---
_id: '1830'
abstract:
- lang: eng
text: To prevent epidemics, insect societies have evolved collective disease defences
that are highly effective at curing exposed individuals and limiting disease transmission
to healthy group members. Grooming is an important sanitary behaviour—either performed
towards oneself (self-grooming) or towards others (allogrooming)—to remove infectious
agents from the body surface of exposed individuals, but at the risk of disease
contraction by the groomer. We use garden ants (Lasius neglectus) and the fungal
pathogen Metarhizium as a model system to study how pathogen presence affects
self-grooming and allogrooming between exposed and healthy individuals. We develop
an epidemiological SIS model to explore how experimentally observed grooming patterns
affect disease spread within the colony, thereby providing a direct link between
the expression and direction of sanitary behaviours, and their effects on colony-level
epidemiology. We find that fungus-exposed ants increase self-grooming, while simultaneously
decreasing allogrooming. This behavioural modulation seems universally adaptive
and is predicted to contain disease spread in a great variety of host–pathogen
systems. In contrast, allogrooming directed towards pathogen-exposed individuals
might both increase and decrease disease risk. Our model reveals that the effect
of allogrooming depends on the balance between pathogen infectiousness and efficiency
of social host defences, which are likely to vary across host–pathogen systems.
acknowledgement: We thank Meghan L. Vyleta for the genetical fungal strain characterization
and Eva Sixt for ant drawings, Matthias Konrad for discussion and Christopher D.
Pull, Barbara Casillas-Peréz, Sebastian Novak, as well as three anonymous reviewers
and the theme issue editors Peter Kappeler and Charlie Nunn for valuable comments
on the manuscript.
article_processing_charge: No
article_type: original
author:
- first_name: Fabian
full_name: Theis, Fabian
last_name: Theis
- first_name: Line V
full_name: Ugelvig, Line V
id: 3DC97C8E-F248-11E8-B48F-1D18A9856A87
last_name: Ugelvig
orcid: 0000-0003-1832-8883
- first_name: Carsten
full_name: Marr, Carsten
last_name: Marr
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
citation:
ama: Theis F, Ugelvig LV, Marr C, Cremer S. Opposing effects of allogrooming on
disease transmission in ant societies. Philosophical Transactions of the Royal
Society of London Series B, Biological Sciences. 2015;370(1669). doi:10.1098/rstb.2014.0108
apa: Theis, F., Ugelvig, L. V., Marr, C., & Cremer, S. (2015). Opposing effects
of allogrooming on disease transmission in ant societies. Philosophical Transactions
of the Royal Society of London. Series B, Biological Sciences. Royal Society,
The. https://doi.org/10.1098/rstb.2014.0108
chicago: Theis, Fabian, Line V Ugelvig, Carsten Marr, and Sylvia Cremer. “Opposing
Effects of Allogrooming on Disease Transmission in Ant Societies.” Philosophical
Transactions of the Royal Society of London. Series B, Biological Sciences.
Royal Society, The, 2015. https://doi.org/10.1098/rstb.2014.0108.
ieee: F. Theis, L. V. Ugelvig, C. Marr, and S. Cremer, “Opposing effects of allogrooming
on disease transmission in ant societies,” Philosophical Transactions of the
Royal Society of London. Series B, Biological Sciences, vol. 370, no. 1669.
Royal Society, The, 2015.
ista: Theis F, Ugelvig LV, Marr C, Cremer S. 2015. Opposing effects of allogrooming
on disease transmission in ant societies. Philosophical Transactions of the Royal
Society of London. Series B, Biological Sciences. 370(1669).
mla: Theis, Fabian, et al. “Opposing Effects of Allogrooming on Disease Transmission
in Ant Societies.” Philosophical Transactions of the Royal Society of London.
Series B, Biological Sciences, vol. 370, no. 1669, Royal Society, The, 2015,
doi:10.1098/rstb.2014.0108.
short: F. Theis, L.V. Ugelvig, C. Marr, S. Cremer, Philosophical Transactions of
the Royal Society of London. Series B, Biological Sciences 370 (2015).
date_created: 2018-12-11T11:54:15Z
date_published: 2015-05-26T00:00:00Z
date_updated: 2023-02-23T14:06:12Z
day: '26'
department:
- _id: SyCr
doi: 10.1098/rstb.2014.0108
ec_funded: 1
external_id:
pmid:
- '25870394'
intvolume: ' 370'
issue: '1669'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410374/
month: '05'
oa: 1
oa_version: Submitted Version
pmid: 1
project:
- _id: 25DC711C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '243071'
name: 'Social Vaccination in Ant Colonies: from Individual Mechanisms to Society
Effects'
- _id: 25DDF0F0-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '302004'
name: 'Pathogen Detectors Collective disease defence and pathogen detection abilities
in ant societies: a chemo-neuro-immunological approach'
- _id: 25E0E184-B435-11E9-9278-68D0E5697425
name: Antnet
- _id: 25E24DB2-B435-11E9-9278-68D0E5697425
name: Fellowship of Wissenschaftskolleg zu Berlin
publication: Philosophical Transactions of the Royal Society of London. Series B,
Biological Sciences
publication_identifier:
eissn:
- 1471-2970
issn:
- 0962-8436
publication_status: published
publisher: Royal Society, The
publist_id: '5273'
quality_controlled: '1'
related_material:
record:
- id: '9721'
relation: research_data
status: public
scopus_import: '1'
status: public
title: Opposing effects of allogrooming on disease transmission in ant societies
type: journal_article
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
volume: 370
year: '2015'
...
---
_id: '9721'
abstract:
- lang: eng
text: To prevent epidemics, insect societies have evolved collective disease defences
that are highly effective at curing exposed individuals and limiting disease transmission
to healthy group members. Grooming is an important sanitary behaviour—either performed
towards oneself (self-grooming) or towards others (allogrooming)—to remove infectious
agents from the body surface of exposed individuals, but at the risk of disease
contraction by the groomer. We use garden ants (Lasius neglectus) and the fungal
pathogen Metarhizium as a model system to study how pathogen presence affects
self-grooming and allogrooming between exposed and healthy individuals. We develop
an epidemiological SIS model to explore how experimentally observed grooming patterns
affect disease spread within the colony, thereby providing a direct link between
the expression and direction of sanitary behaviours, and their effects on colony-level
epidemiology. We find that fungus-exposed ants increase self-grooming, while simultaneously
decreasing allogrooming. This behavioural modulation seems universally adaptive
and is predicted to contain disease spread in a great variety of host–pathogen
systems. In contrast, allogrooming directed towards pathogen-exposed individuals
might both increase and decrease disease risk. Our model reveals that the effect
of allogrooming depends on the balance between pathogen infectiousness and efficiency
of social host defences, which are likely to vary across host–pathogen systems.
article_processing_charge: No
author:
- first_name: Fabian
full_name: Theis, Fabian
last_name: Theis
- first_name: Line V
full_name: Ugelvig, Line V
id: 3DC97C8E-F248-11E8-B48F-1D18A9856A87
last_name: Ugelvig
orcid: 0000-0003-1832-8883
- first_name: Carsten
full_name: Marr, Carsten
last_name: Marr
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
citation:
ama: 'Theis F, Ugelvig LV, Marr C, Cremer S. Data from: Opposing effects of allogrooming
on disease transmission in ant societies. 2015. doi:10.5061/dryad.dj2bf'
apa: 'Theis, F., Ugelvig, L. V., Marr, C., & Cremer, S. (2015). Data from: Opposing
effects of allogrooming on disease transmission in ant societies. Dryad. https://doi.org/10.5061/dryad.dj2bf'
chicago: 'Theis, Fabian, Line V Ugelvig, Carsten Marr, and Sylvia Cremer. “Data
from: Opposing Effects of Allogrooming on Disease Transmission in Ant Societies.”
Dryad, 2015. https://doi.org/10.5061/dryad.dj2bf.'
ieee: 'F. Theis, L. V. Ugelvig, C. Marr, and S. Cremer, “Data from: Opposing effects
of allogrooming on disease transmission in ant societies.” Dryad, 2015.'
ista: 'Theis F, Ugelvig LV, Marr C, Cremer S. 2015. Data from: Opposing effects
of allogrooming on disease transmission in ant societies, Dryad, 10.5061/dryad.dj2bf.'
mla: 'Theis, Fabian, et al. Data from: Opposing Effects of Allogrooming on Disease
Transmission in Ant Societies. Dryad, 2015, doi:10.5061/dryad.dj2bf.'
short: F. Theis, L.V. Ugelvig, C. Marr, S. Cremer, (2015).
date_created: 2021-07-26T09:38:36Z
date_published: 2015-12-29T00:00:00Z
date_updated: 2023-02-23T10:16:22Z
day: '29'
department:
- _id: SyCr
doi: 10.5061/dryad.dj2bf
main_file_link:
- open_access: '1'
url: https://doi.org/10.5061/dryad.dj2bf
month: '12'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
record:
- id: '1830'
relation: used_in_publication
status: public
status: public
title: 'Data from: Opposing effects of allogrooming on disease transmission in ant
societies'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2015'
...
---
_id: '9718'
article_processing_charge: No
author:
- first_name: Tamar
full_name: Friedlander, Tamar
id: 36A5845C-F248-11E8-B48F-1D18A9856A87
last_name: Friedlander
- first_name: Avraham E.
full_name: Mayo, Avraham E.
last_name: Mayo
- first_name: Tsvi
full_name: Tlusty, Tsvi
last_name: Tlusty
- first_name: Uri
full_name: Alon, Uri
last_name: Alon
citation:
ama: Friedlander T, Mayo AE, Tlusty T, Alon U. Supporting information text. 2015.
doi:10.1371/journal.pcbi.1004055.s001
apa: Friedlander, T., Mayo, A. E., Tlusty, T., & Alon, U. (2015). Supporting
information text. Public Library of Science. https://doi.org/10.1371/journal.pcbi.1004055.s001
chicago: Friedlander, Tamar, Avraham E. Mayo, Tsvi Tlusty, and Uri Alon. “Supporting
Information Text.” Public Library of Science, 2015. https://doi.org/10.1371/journal.pcbi.1004055.s001.
ieee: T. Friedlander, A. E. Mayo, T. Tlusty, and U. Alon, “Supporting information
text.” Public Library of Science, 2015.
ista: Friedlander T, Mayo AE, Tlusty T, Alon U. 2015. Supporting information text,
Public Library of Science, 10.1371/journal.pcbi.1004055.s001.
mla: Friedlander, Tamar, et al. Supporting Information Text. Public Library
of Science, 2015, doi:10.1371/journal.pcbi.1004055.s001.
short: T. Friedlander, A.E. Mayo, T. Tlusty, U. Alon, (2015).
date_created: 2021-07-26T08:35:23Z
date_published: 2015-03-23T00:00:00Z
date_updated: 2023-02-23T10:16:13Z
day: '23'
department:
- _id: GaTk
doi: 10.1371/journal.pcbi.1004055.s001
month: '03'
oa_version: Published Version
publisher: Public Library of Science
related_material:
record:
- id: '1827'
relation: used_in_publication
status: public
status: public
title: Supporting information text
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2015'
...
---
_id: '1793'
abstract:
- lang: eng
text: We present a software platform for reconstructing and analyzing the growth
of a plant root system from a time-series of 3D voxelized shapes. It aligns the
shapes with each other, constructs a geometric graph representation together with
the function that records the time of growth, and organizes the branches into
a hierarchy that reflects the order of creation. The software includes the automatic
computation of structural and dynamic traits for each root in the system enabling
the quantification of growth on fine-scale. These are important advances in plant
phenotyping with applications to the study of genetic and environmental influences
on growth.
article_number: e0127657
author:
- first_name: Olga
full_name: Symonova, Olga
id: 3C0C7BC6-F248-11E8-B48F-1D18A9856A87
last_name: Symonova
- first_name: Christopher
full_name: Topp, Christopher
last_name: Topp
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
citation:
ama: 'Symonova O, Topp C, Edelsbrunner H. DynamicRoots: A software platform for
the reconstruction and analysis of growing plant roots. PLoS One. 2015;10(6).
doi:10.1371/journal.pone.0127657'
apa: 'Symonova, O., Topp, C., & Edelsbrunner, H. (2015). DynamicRoots: A software
platform for the reconstruction and analysis of growing plant roots. PLoS One.
Public Library of Science. https://doi.org/10.1371/journal.pone.0127657'
chicago: 'Symonova, Olga, Christopher Topp, and Herbert Edelsbrunner. “DynamicRoots:
A Software Platform for the Reconstruction and Analysis of Growing Plant Roots.”
PLoS One. Public Library of Science, 2015. https://doi.org/10.1371/journal.pone.0127657.'
ieee: 'O. Symonova, C. Topp, and H. Edelsbrunner, “DynamicRoots: A software platform
for the reconstruction and analysis of growing plant roots,” PLoS One,
vol. 10, no. 6. Public Library of Science, 2015.'
ista: 'Symonova O, Topp C, Edelsbrunner H. 2015. DynamicRoots: A software platform
for the reconstruction and analysis of growing plant roots. PLoS One. 10(6), e0127657.'
mla: 'Symonova, Olga, et al. “DynamicRoots: A Software Platform for the Reconstruction
and Analysis of Growing Plant Roots.” PLoS One, vol. 10, no. 6, e0127657,
Public Library of Science, 2015, doi:10.1371/journal.pone.0127657.'
short: O. Symonova, C. Topp, H. Edelsbrunner, PLoS One 10 (2015).
date_created: 2018-12-11T11:54:02Z
date_published: 2015-06-01T00:00:00Z
date_updated: 2023-02-23T14:06:33Z
day: '01'
ddc:
- '000'
department:
- _id: MaJö
- _id: HeEd
doi: 10.1371/journal.pone.0127657
file:
- access_level: open_access
checksum: d20f26461ca575276ad3ed9ce4bfc787
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:15:30Z
date_updated: 2020-07-14T12:45:16Z
file_id: '5150'
file_name: IST-2016-454-v1+1_journal.pone.0127657.pdf
file_size: 1850825
relation: main_file
file_date_updated: 2020-07-14T12:45:16Z
has_accepted_license: '1'
intvolume: ' 10'
issue: '6'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
publication: PLoS One
publication_status: published
publisher: Public Library of Science
publist_id: '5318'
pubrep_id: '454'
quality_controlled: '1'
related_material:
record:
- id: '9737'
relation: research_data
status: public
scopus_import: 1
status: public
title: 'DynamicRoots: A software platform for the reconstruction and analysis of growing
plant roots'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2015'
...
---
_id: '9737'
article_processing_charge: No
author:
- first_name: Olga
full_name: Symonova, Olga
id: 3C0C7BC6-F248-11E8-B48F-1D18A9856A87
last_name: Symonova
- first_name: Christopher
full_name: Topp, Christopher
last_name: Topp
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
citation:
ama: Symonova O, Topp C, Edelsbrunner H. Root traits computed by DynamicRoots for
the maize root shown in fig 2. 2015. doi:10.1371/journal.pone.0127657.s001
apa: Symonova, O., Topp, C., & Edelsbrunner, H. (2015). Root traits computed
by DynamicRoots for the maize root shown in fig 2. Public Library of Science.
https://doi.org/10.1371/journal.pone.0127657.s001
chicago: Symonova, Olga, Christopher Topp, and Herbert Edelsbrunner. “Root Traits
Computed by DynamicRoots for the Maize Root Shown in Fig 2.” Public Library of
Science, 2015. https://doi.org/10.1371/journal.pone.0127657.s001.
ieee: O. Symonova, C. Topp, and H. Edelsbrunner, “Root traits computed by DynamicRoots
for the maize root shown in fig 2.” Public Library of Science, 2015.
ista: Symonova O, Topp C, Edelsbrunner H. 2015. Root traits computed by DynamicRoots
for the maize root shown in fig 2, Public Library of Science, 10.1371/journal.pone.0127657.s001.
mla: Symonova, Olga, et al. Root Traits Computed by DynamicRoots for the Maize
Root Shown in Fig 2. Public Library of Science, 2015, doi:10.1371/journal.pone.0127657.s001.
short: O. Symonova, C. Topp, H. Edelsbrunner, (2015).
date_created: 2021-07-28T06:20:13Z
date_published: 2015-06-01T00:00:00Z
date_updated: 2023-02-23T10:14:42Z
day: '01'
department:
- _id: MaJö
- _id: HeEd
doi: 10.1371/journal.pone.0127657.s001
month: '06'
oa_version: Published Version
publisher: Public Library of Science
related_material:
record:
- id: '1793'
relation: used_in_publication
status: public
status: public
title: Root traits computed by DynamicRoots for the maize root shown in fig 2
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2015'
...
---
_id: '1827'
abstract:
- lang: eng
text: Bow-tie or hourglass structure is a common architectural feature found in
many biological systems. A bow-tie in a multi-layered structure occurs when intermediate
layers have much fewer components than the input and output layers. Examples include
metabolism where a handful of building blocks mediate between multiple input nutrients
and multiple output biomass components, and signaling networks where information
from numerous receptor types passes through a small set of signaling pathways
to regulate multiple output genes. Little is known, however, about how bow-tie
architectures evolve. Here, we address the evolution of bow-tie architectures
using simulations of multi-layered systems evolving to fulfill a given input-output
goal. We find that bow-ties spontaneously evolve when the information in the evolutionary
goal can be compressed. Mathematically speaking, bow-ties evolve when the rank
of the input-output matrix describing the evolutionary goal is deficient. The
maximal compression possible (the rank of the goal) determines the size of the
narrowest part of the network—that is the bow-tie. A further requirement is that
a process is active to reduce the number of links in the network, such as product-rule
mutations, otherwise a non-bow-tie solution is found in the evolutionary simulations.
This offers a mechanism to understand a common architectural principle of biological
systems, and a way to quantitate the effective rank of the goals under which they
evolved.
article_processing_charge: No
author:
- first_name: Tamar
full_name: Friedlander, Tamar
id: 36A5845C-F248-11E8-B48F-1D18A9856A87
last_name: Friedlander
- first_name: Avraham
full_name: Mayo, Avraham
last_name: Mayo
- first_name: Tsvi
full_name: Tlusty, Tsvi
last_name: Tlusty
- first_name: Uri
full_name: Alon, Uri
last_name: Alon
citation:
ama: Friedlander T, Mayo A, Tlusty T, Alon U. Evolution of bow-tie architectures
in biology. PLoS Computational Biology. 2015;11(3). doi:10.1371/journal.pcbi.1004055
apa: Friedlander, T., Mayo, A., Tlusty, T., & Alon, U. (2015). Evolution of
bow-tie architectures in biology. PLoS Computational Biology. Public Library
of Science. https://doi.org/10.1371/journal.pcbi.1004055
chicago: Friedlander, Tamar, Avraham Mayo, Tsvi Tlusty, and Uri Alon. “Evolution
of Bow-Tie Architectures in Biology.” PLoS Computational Biology. Public
Library of Science, 2015. https://doi.org/10.1371/journal.pcbi.1004055.
ieee: T. Friedlander, A. Mayo, T. Tlusty, and U. Alon, “Evolution of bow-tie architectures
in biology,” PLoS Computational Biology, vol. 11, no. 3. Public Library
of Science, 2015.
ista: Friedlander T, Mayo A, Tlusty T, Alon U. 2015. Evolution of bow-tie architectures
in biology. PLoS Computational Biology. 11(3).
mla: Friedlander, Tamar, et al. “Evolution of Bow-Tie Architectures in Biology.”
PLoS Computational Biology, vol. 11, no. 3, Public Library of Science,
2015, doi:10.1371/journal.pcbi.1004055.
short: T. Friedlander, A. Mayo, T. Tlusty, U. Alon, PLoS Computational Biology 11
(2015).
date_created: 2018-12-11T11:54:14Z
date_published: 2015-03-23T00:00:00Z
date_updated: 2023-02-23T14:07:51Z
day: '23'
ddc:
- '576'
department:
- _id: GaTk
doi: 10.1371/journal.pcbi.1004055
ec_funded: 1
file:
- access_level: open_access
checksum: b8aa66f450ff8de393014b87ec7d2efb
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:15:39Z
date_updated: 2020-07-14T12:45:17Z
file_id: '5161'
file_name: IST-2016-452-v1+1_journal.pcbi.1004055.pdf
file_size: 1811647
relation: main_file
file_date_updated: 2020-07-14T12:45:17Z
has_accepted_license: '1'
intvolume: ' 11'
issue: '3'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: PLoS Computational Biology
publication_status: published
publisher: Public Library of Science
publist_id: '5278'
pubrep_id: '452'
quality_controlled: '1'
related_material:
record:
- id: '9718'
relation: research_data
status: public
- id: '9773'
relation: research_data
status: public
scopus_import: 1
status: public
title: Evolution of bow-tie architectures in biology
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2015'
...
---
_id: '1809'
abstract:
- lang: eng
text: 'Background: Indirect genetic effects (IGEs) occur when genes expressed in
one individual alter the expression of traits in social partners. Previous studies
focused on the evolutionary consequences and evolutionary dynamics of IGEs, using
equilibrium solutions to predict phenotypes in subsequent generations. However,
whether or not such steady states may be reached may depend on the dynamics of
interactions themselves. Results: In our study, we focus on the dynamics of social
interactions and indirect genetic effects and investigate how they modify phenotypes
over time. Unlike previous IGE studies, we do not analyse evolutionary dynamics;
rather we consider within-individual phenotypic changes, also referred to as phenotypic
plasticity. We analyse iterative interactions, when individuals interact in a
series of discontinuous events, and investigate the stability of steady state
solutions and the dependence on model parameters, such as population size, strength,
and the nature of interactions. We show that for interactions where a feedback
loop occurs, the possible parameter space of interaction strength is fairly limited,
affecting the evolutionary consequences of IGEs. We discuss the implications of
our results for current IGE model predictions and their limitations.'
author:
- first_name: Barbora
full_name: Trubenova, Barbora
id: 42302D54-F248-11E8-B48F-1D18A9856A87
last_name: Trubenova
orcid: 0000-0002-6873-2967
- first_name: Sebastian
full_name: Novak, Sebastian
id: 461468AE-F248-11E8-B48F-1D18A9856A87
last_name: Novak
- first_name: Reinmar
full_name: Hager, Reinmar
last_name: Hager
citation:
ama: Trubenova B, Novak S, Hager R. Indirect genetic effects and the dynamics of
social interactions. PLoS One. 2015;10(5). doi:10.1371/journal.pone.0126907
apa: Trubenova, B., Novak, S., & Hager, R. (2015). Indirect genetic effects
and the dynamics of social interactions. PLoS One. Public Library of Science.
https://doi.org/10.1371/journal.pone.0126907
chicago: Trubenova, Barbora, Sebastian Novak, and Reinmar Hager. “Indirect Genetic
Effects and the Dynamics of Social Interactions.” PLoS One. Public Library
of Science, 2015. https://doi.org/10.1371/journal.pone.0126907.
ieee: B. Trubenova, S. Novak, and R. Hager, “Indirect genetic effects and the dynamics
of social interactions,” PLoS One, vol. 10, no. 5. Public Library of Science,
2015.
ista: Trubenova B, Novak S, Hager R. 2015. Indirect genetic effects and the dynamics
of social interactions. PLoS One. 10(5).
mla: Trubenova, Barbora, et al. “Indirect Genetic Effects and the Dynamics of Social
Interactions.” PLoS One, vol. 10, no. 5, Public Library of Science, 2015,
doi:10.1371/journal.pone.0126907.
short: B. Trubenova, S. Novak, R. Hager, PLoS One 10 (2015).
date_created: 2018-12-11T11:54:07Z
date_published: 2015-05-18T00:00:00Z
date_updated: 2023-02-23T14:07:48Z
day: '18'
ddc:
- '570'
- '576'
department:
- _id: NiBa
doi: 10.1371/journal.pone.0126907
file:
- access_level: open_access
checksum: d3a4a58ef4bd3b3e2f32b7fd7af4a743
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:09:07Z
date_updated: 2020-07-14T12:45:17Z
file_id: '4730'
file_name: IST-2016-453-v1+1_journal.pone.0126907.pdf
file_size: 2748982
relation: main_file
file_date_updated: 2020-07-14T12:45:17Z
has_accepted_license: '1'
intvolume: ' 10'
issue: '5'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
publication: PLoS One
publication_status: published
publisher: Public Library of Science
publist_id: '5299'
pubrep_id: '453'
quality_controlled: '1'
related_material:
record:
- id: '9715'
relation: research_data
status: public
- id: '9772'
relation: research_data
status: public
scopus_import: 1
status: public
title: Indirect genetic effects and the dynamics of social interactions
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2015'
...
---
_id: '9772'
article_processing_charge: No
author:
- first_name: Barbora
full_name: Trubenova, Barbora
id: 42302D54-F248-11E8-B48F-1D18A9856A87
last_name: Trubenova
orcid: 0000-0002-6873-2967
- first_name: Sebastian
full_name: Novak, Sebastian
id: 461468AE-F248-11E8-B48F-1D18A9856A87
last_name: Novak
- first_name: Reinmar
full_name: Hager, Reinmar
last_name: Hager
citation:
ama: Trubenova B, Novak S, Hager R. Description of the agent based simulations.
2015. doi:10.1371/journal.pone.0126907.s003
apa: Trubenova, B., Novak, S., & Hager, R. (2015). Description of the agent
based simulations. Public Library of Science. https://doi.org/10.1371/journal.pone.0126907.s003
chicago: Trubenova, Barbora, Sebastian Novak, and Reinmar Hager. “Description of
the Agent Based Simulations.” Public Library of Science, 2015. https://doi.org/10.1371/journal.pone.0126907.s003.
ieee: B. Trubenova, S. Novak, and R. Hager, “Description of the agent based simulations.”
Public Library of Science, 2015.
ista: Trubenova B, Novak S, Hager R. 2015. Description of the agent based simulations,
Public Library of Science, 10.1371/journal.pone.0126907.s003.
mla: Trubenova, Barbora, et al. Description of the Agent Based Simulations.
Public Library of Science, 2015, doi:10.1371/journal.pone.0126907.s003.
short: B. Trubenova, S. Novak, R. Hager, (2015).
date_created: 2021-08-05T12:55:20Z
date_published: 2015-05-18T00:00:00Z
date_updated: 2023-02-23T10:15:25Z
day: '18'
department:
- _id: NiBa
doi: 10.1371/journal.pone.0126907.s003
month: '05'
oa_version: Published Version
publisher: Public Library of Science
related_material:
record:
- id: '1809'
relation: used_in_publication
status: public
status: public
title: Description of the agent based simulations
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2015'
...
---
_id: '9773'
article_processing_charge: No
author:
- first_name: Tamar
full_name: Friedlander, Tamar
id: 36A5845C-F248-11E8-B48F-1D18A9856A87
last_name: Friedlander
- first_name: Avraham E.
full_name: Mayo, Avraham E.
last_name: Mayo
- first_name: Tsvi
full_name: Tlusty, Tsvi
last_name: Tlusty
- first_name: Uri
full_name: Alon, Uri
last_name: Alon
citation:
ama: Friedlander T, Mayo AE, Tlusty T, Alon U. Evolutionary simulation code. 2015.
doi:10.1371/journal.pcbi.1004055.s002
apa: Friedlander, T., Mayo, A. E., Tlusty, T., & Alon, U. (2015). Evolutionary
simulation code. Public Library of Science. https://doi.org/10.1371/journal.pcbi.1004055.s002
chicago: Friedlander, Tamar, Avraham E. Mayo, Tsvi Tlusty, and Uri Alon. “Evolutionary
Simulation Code.” Public Library of Science, 2015. https://doi.org/10.1371/journal.pcbi.1004055.s002.
ieee: T. Friedlander, A. E. Mayo, T. Tlusty, and U. Alon, “Evolutionary simulation
code.” Public Library of Science, 2015.
ista: Friedlander T, Mayo AE, Tlusty T, Alon U. 2015. Evolutionary simulation code,
Public Library of Science, 10.1371/journal.pcbi.1004055.s002.
mla: Friedlander, Tamar, et al. Evolutionary Simulation Code. Public Library
of Science, 2015, doi:10.1371/journal.pcbi.1004055.s002.
short: T. Friedlander, A.E. Mayo, T. Tlusty, U. Alon, (2015).
date_created: 2021-08-05T12:58:07Z
date_published: 2015-03-23T00:00:00Z
date_updated: 2023-02-23T10:16:13Z
day: '23'
department:
- _id: GaTk
doi: 10.1371/journal.pcbi.1004055.s002
month: '03'
oa_version: Published Version
publisher: Public Library of Science
related_material:
record:
- id: '1827'
relation: used_in_publication
status: public
status: public
title: Evolutionary simulation code
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2015'
...
---
_id: '1566'
abstract:
- lang: eng
text: Deposits of misfolded proteins in the human brain are associated with the
development of many neurodegenerative diseases. Recent studies show that these
proteins have common traits even at the monomer level. Among them, a polyglutamine
region that is present in huntingtin is known to exhibit a correlation between
the length of the chain and the severity as well as the earliness of the onset
of Huntington disease. Here, we apply bias exchange molecular dynamics to generate
structures of polyglutamine expansions of several lengths and characterize the
resulting independent conformations. We compare the properties of these conformations
to those of the standard proteins, as well as to other homopolymeric tracts. We
find that, similar to the previously studied polyvaline chains, the set of possible
transient folds is much broader than the set of known-to-date folds, although
the conformations have different structures. We show that the mechanical stability
is not related to any simple geometrical characteristics of the structures. We
demonstrate that long polyglutamine expansions result in higher mechanical stability
than the shorter ones. They also have a longer life span and are substantially
more prone to form knotted structures. The knotted region has an average length
of 35 residues, similar to the typical threshold for most polyglutamine-related
diseases. Similarly, changes in shape and mechanical stability appear once the
total length of the peptide exceeds this threshold of 35 glutamine residues. We
suggest that knotted conformers may also harm the cellular machinery and thus
lead to disease.
acknowledgement: 'We acknowledge the support by the EU Joint Programme in Neurodegenerative
Diseases (JPND AC14/00037) project. The project is supported through the following
funding organisations under the aegis of JPND—www.jpnd.eu: Ireland, HRB; Poland,
National Science Centre; and Spain, ISCIII. '
article_number: e1004541
author:
- first_name: Àngel
full_name: Gómez Sicilia, Àngel
last_name: Gómez Sicilia
- first_name: Mateusz K
full_name: Sikora, Mateusz K
id: 2F74BCDE-F248-11E8-B48F-1D18A9856A87
last_name: Sikora
- first_name: Marek
full_name: Cieplak, Marek
last_name: Cieplak
- first_name: Mariano
full_name: Carrión Vázquez, Mariano
last_name: Carrión Vázquez
citation:
ama: Gómez Sicilia À, Sikora MK, Cieplak M, Carrión Vázquez M. An exploration of
the universe of polyglutamine structures. PLoS Computational Biology. 2015;11(10).
doi:10.1371/journal.pcbi.1004541
apa: Gómez Sicilia, À., Sikora, M. K., Cieplak, M., & Carrión Vázquez, M. (2015).
An exploration of the universe of polyglutamine structures. PLoS Computational
Biology. Public Library of Science. https://doi.org/10.1371/journal.pcbi.1004541
chicago: Gómez Sicilia, Àngel, Mateusz K Sikora, Marek Cieplak, and Mariano Carrión
Vázquez. “An Exploration of the Universe of Polyglutamine Structures.” PLoS
Computational Biology. Public Library of Science, 2015. https://doi.org/10.1371/journal.pcbi.1004541.
ieee: À. Gómez Sicilia, M. K. Sikora, M. Cieplak, and M. Carrión Vázquez, “An exploration
of the universe of polyglutamine structures,” PLoS Computational Biology,
vol. 11, no. 10. Public Library of Science, 2015.
ista: Gómez Sicilia À, Sikora MK, Cieplak M, Carrión Vázquez M. 2015. An exploration
of the universe of polyglutamine structures. PLoS Computational Biology. 11(10),
e1004541.
mla: Gómez Sicilia, Àngel, et al. “An Exploration of the Universe of Polyglutamine
Structures.” PLoS Computational Biology, vol. 11, no. 10, e1004541, Public
Library of Science, 2015, doi:10.1371/journal.pcbi.1004541.
short: À. Gómez Sicilia, M.K. Sikora, M. Cieplak, M. Carrión Vázquez, PLoS Computational
Biology 11 (2015).
date_created: 2018-12-11T11:52:45Z
date_published: 2015-10-23T00:00:00Z
date_updated: 2023-02-23T14:05:55Z
day: '23'
ddc:
- '570'
department:
- _id: CaHe
doi: 10.1371/journal.pcbi.1004541
file:
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checksum: 8b67d729be663bfc9af04bfd94459655
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:16:21Z
date_updated: 2020-07-14T12:45:02Z
file_id: '5207'
file_name: IST-2016-478-v1+1_journal.pcbi.1004541.pdf
file_size: 1412511
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file_date_updated: 2020-07-14T12:45:02Z
has_accepted_license: '1'
intvolume: ' 11'
issue: '10'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
publication: PLoS Computational Biology
publication_status: published
publisher: Public Library of Science
publist_id: '5605'
pubrep_id: '478'
quality_controlled: '1'
related_material:
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relation: research_data
status: public
scopus_import: 1
status: public
title: An exploration of the universe of polyglutamine structures
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2015'
...