---
_id: '29'
abstract:
- lang: eng
text: Social insects have evolved enormous capacities to collectively build nests
and defend their colonies against both predators and pathogens. The latter is
achieved by a combination of individual immune responses and sophisticated collective
behavioral and organizational disease defenses, that is, social immunity. We investigated
how the presence or absence of these social defense lines affects individual-level
immunity in ant queens after bacterial infection. To this end, we injected queens
of the ant Linepithema humile with a mix of gram+ and gram− bacteria or a control
solution, reared them either with workers or alone and analyzed their gene expression
patterns at 2, 4, 8, and 12 hr post-injection, using RNA-seq. This allowed us
to test for the effect of bacterial infection, social context, as well as the
interaction between the two over the course of infection and raising of an immune
response. We found that social isolation per se affected queen gene expression
for metabolism genes, but not for immune genes. When infected, queens reared with
and without workers up-regulated similar numbers of innate immune genes revealing
activation of Toll and Imd signaling pathways and melanization. Interestingly,
however, they mostly regulated different genes along the pathways and showed a
different pattern of overall gene up-regulation or down-regulation. Hence, we
can conclude that the absence of workers does not compromise the onset of an individual
immune response by the queens, but that the social environment impacts the route
of the individual innate immune responses.
article_processing_charge: No
author:
- first_name: Lumi
full_name: Viljakainen, Lumi
last_name: Viljakainen
- first_name: Jaana
full_name: Jurvansuu, Jaana
last_name: Jurvansuu
- first_name: Ida
full_name: Holmberg, Ida
last_name: Holmberg
- first_name: Tobias
full_name: Pamminger, Tobias
last_name: Pamminger
- first_name: Silvio
full_name: Erler, Silvio
last_name: Erler
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
citation:
ama: Viljakainen L, Jurvansuu J, Holmberg I, Pamminger T, Erler S, Cremer S. Social
environment affects the transcriptomic response to bacteria in ant queens. Ecology
and Evolution. 2018;8(22):11031-11070. doi:10.1002/ece3.4573
apa: Viljakainen, L., Jurvansuu, J., Holmberg, I., Pamminger, T., Erler, S., &
Cremer, S. (2018). Social environment affects the transcriptomic response to bacteria
in ant queens. Ecology and Evolution. Wiley. https://doi.org/10.1002/ece3.4573
chicago: Viljakainen, Lumi, Jaana Jurvansuu, Ida Holmberg, Tobias Pamminger, Silvio
Erler, and Sylvia Cremer. “Social Environment Affects the Transcriptomic Response
to Bacteria in Ant Queens.” Ecology and Evolution. Wiley, 2018. https://doi.org/10.1002/ece3.4573.
ieee: L. Viljakainen, J. Jurvansuu, I. Holmberg, T. Pamminger, S. Erler, and S.
Cremer, “Social environment affects the transcriptomic response to bacteria in
ant queens,” Ecology and Evolution, vol. 8, no. 22. Wiley, pp. 11031–11070,
2018.
ista: Viljakainen L, Jurvansuu J, Holmberg I, Pamminger T, Erler S, Cremer S. 2018.
Social environment affects the transcriptomic response to bacteria in ant queens.
Ecology and Evolution. 8(22), 11031–11070.
mla: Viljakainen, Lumi, et al. “Social Environment Affects the Transcriptomic Response
to Bacteria in Ant Queens.” Ecology and Evolution, vol. 8, no. 22, Wiley,
2018, pp. 11031–70, doi:10.1002/ece3.4573.
short: L. Viljakainen, J. Jurvansuu, I. Holmberg, T. Pamminger, S. Erler, S. Cremer,
Ecology and Evolution 8 (2018) 11031–11070.
date_created: 2018-12-11T11:44:15Z
date_published: 2018-11-01T00:00:00Z
date_updated: 2023-09-19T09:29:12Z
day: '01'
ddc:
- '576'
- '591'
department:
- _id: SyCr
doi: 10.1002/ece3.4573
external_id:
isi:
- '000451611000032'
file:
- access_level: open_access
checksum: 0d1355c78627ca7210aadd9a17a01915
content_type: application/pdf
creator: dernst
date_created: 2018-12-17T08:27:04Z
date_updated: 2020-07-14T12:45:52Z
file_id: '5682'
file_name: Viljakainen_et_al-2018-Ecology_and_Evolution.pdf
file_size: 1272096
relation: main_file
file_date_updated: 2020-07-14T12:45:52Z
has_accepted_license: '1'
intvolume: ' 8'
isi: 1
issue: '22'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '11'
oa: 1
oa_version: Published Version
page: 11031-11070
publication: Ecology and Evolution
publication_identifier:
issn:
- '20457758'
publication_status: published
publisher: Wiley
publist_id: '8026'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Social environment affects the transcriptomic response to bacteria in ant queens
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 8
year: '2018'
...
---
_id: '806'
abstract:
- lang: eng
text: Social insect colonies have evolved many collectively performed adaptations
that reduce the impact of infectious disease and that are expected to maximize
their fitness. This colony-level protection is termed social immunity, and it
enhances the health and survival of the colony. In this review, we address how
social immunity emerges from its mechanistic components to produce colony-level
disease avoidance, resistance, and tolerance. To understand the evolutionary causes
and consequences of social immunity, we highlight the need for studies that evaluate
the effects of social immunity on colony fitness. We discuss the role that host
life history and ecology have on predicted eco-evolutionary dynamics, which differ
among the social insect lineages. Throughout the review, we highlight current
gaps in our knowledge and promising avenues for future research, which we hope
will bring us closer to an integrated understanding of socio-eco-evo-immunology.
article_processing_charge: No
author:
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
- first_name: Christopher
full_name: Pull, Christopher
id: 3C7F4840-F248-11E8-B48F-1D18A9856A87
last_name: Pull
orcid: 0000-0003-1122-3982
- first_name: Matthias
full_name: Fürst, Matthias
id: 393B1196-F248-11E8-B48F-1D18A9856A87
last_name: Fürst
orcid: 0000-0002-3712-925X
citation:
ama: 'Cremer S, Pull C, Fürst M. Social immunity: Emergence and evolution of colony-level
disease protection. Annual Review of Entomology. 2018;63:105-123. doi:10.1146/annurev-ento-020117-043110'
apa: 'Cremer, S., Pull, C., & Fürst, M. (2018). Social immunity: Emergence and
evolution of colony-level disease protection. Annual Review of Entomology.
Annual Reviews. https://doi.org/10.1146/annurev-ento-020117-043110'
chicago: 'Cremer, Sylvia, Christopher Pull, and Matthias Fürst. “Social Immunity:
Emergence and Evolution of Colony-Level Disease Protection.” Annual Review
of Entomology. Annual Reviews, 2018. https://doi.org/10.1146/annurev-ento-020117-043110.'
ieee: 'S. Cremer, C. Pull, and M. Fürst, “Social immunity: Emergence and evolution
of colony-level disease protection,” Annual Review of Entomology, vol.
63. Annual Reviews, pp. 105–123, 2018.'
ista: 'Cremer S, Pull C, Fürst M. 2018. Social immunity: Emergence and evolution
of colony-level disease protection. Annual Review of Entomology. 63, 105–123.'
mla: 'Cremer, Sylvia, et al. “Social Immunity: Emergence and Evolution of Colony-Level
Disease Protection.” Annual Review of Entomology, vol. 63, Annual Reviews,
2018, pp. 105–23, doi:10.1146/annurev-ento-020117-043110.'
short: S. Cremer, C. Pull, M. Fürst, Annual Review of Entomology 63 (2018) 105–123.
date_created: 2018-12-11T11:48:36Z
date_published: 2018-01-07T00:00:00Z
date_updated: 2023-09-19T09:29:45Z
day: '07'
department:
- _id: SyCr
doi: 10.1146/annurev-ento-020117-043110
external_id:
isi:
- '000424633700008'
intvolume: ' 63'
isi: 1
language:
- iso: eng
month: '01'
oa_version: None
page: 105 - 123
publication: Annual Review of Entomology
publication_identifier:
issn:
- 1545-4487
publication_status: published
publisher: Annual Reviews
publist_id: '6844'
quality_controlled: '1'
related_material:
record:
- id: '819'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: 'Social immunity: Emergence and evolution of colony-level disease protection'
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 63
year: '2018'
...
---
_id: '140'
abstract:
- lang: eng
text: Reachability analysis is difficult for hybrid automata with affine differential
equations, because the reach set needs to be approximated. Promising abstraction
techniques usually employ interval methods or template polyhedra. Interval methods
account for dense time and guarantee soundness, and there are interval-based tools
that overapproximate affine flowpipes. But interval methods impose bounded and
rigid shapes, which make refinement expensive and fixpoint detection difficult.
Template polyhedra, on the other hand, can be adapted flexibly and can be unbounded,
but sound template refinement for unbounded reachability analysis has been implemented
only for systems with piecewise constant dynamics. We capitalize on the advantages
of both techniques, combining interval arithmetic and template polyhedra, using
the former to abstract time and the latter to abstract space. During a CEGAR loop,
whenever a spurious error trajectory is found, we compute additional space constraints
and split time intervals, and use these space-time interpolants to eliminate the
counterexample. Space-time interpolation offers a lazy, flexible framework for
increasing precision while guaranteeing soundness, both for error avoidance and
fixpoint detection. To the best of out knowledge, this is the first abstraction
refinement scheme for the reachability analysis over unbounded and dense time
of affine hybrid systems, which is both sound and automatic. We demonstrate the
effectiveness of our algorithm with several benchmark examples, which cannot be
handled by other tools.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Goran
full_name: Frehse, Goran
last_name: Frehse
- first_name: Mirco
full_name: Giacobbe, Mirco
id: 3444EA5E-F248-11E8-B48F-1D18A9856A87
last_name: Giacobbe
orcid: 0000-0001-8180-0904
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
citation:
ama: 'Frehse G, Giacobbe M, Henzinger TA. Space-time interpolants. In: Vol 10981.
Springer; 2018:468-486. doi:10.1007/978-3-319-96145-3_25'
apa: 'Frehse, G., Giacobbe, M., & Henzinger, T. A. (2018). Space-time interpolants
(Vol. 10981, pp. 468–486). Presented at the CAV: Computer Aided Verification,
Oxford, United Kingdom: Springer. https://doi.org/10.1007/978-3-319-96145-3_25'
chicago: Frehse, Goran, Mirco Giacobbe, and Thomas A Henzinger. “Space-Time Interpolants,”
10981:468–86. Springer, 2018. https://doi.org/10.1007/978-3-319-96145-3_25.
ieee: 'G. Frehse, M. Giacobbe, and T. A. Henzinger, “Space-time interpolants,” presented
at the CAV: Computer Aided Verification, Oxford, United Kingdom, 2018, vol. 10981,
pp. 468–486.'
ista: 'Frehse G, Giacobbe M, Henzinger TA. 2018. Space-time interpolants. CAV: Computer
Aided Verification, LNCS, vol. 10981, 468–486.'
mla: Frehse, Goran, et al. Space-Time Interpolants. Vol. 10981, Springer,
2018, pp. 468–86, doi:10.1007/978-3-319-96145-3_25.
short: G. Frehse, M. Giacobbe, T.A. Henzinger, in:, Springer, 2018, pp. 468–486.
conference:
end_date: 2018-07-17
location: Oxford, United Kingdom
name: 'CAV: Computer Aided Verification'
start_date: 2018-07-14
date_created: 2018-12-11T11:44:50Z
date_published: 2018-07-18T00:00:00Z
date_updated: 2023-09-19T09:30:43Z
day: '18'
ddc:
- '005'
department:
- _id: ToHe
doi: 10.1007/978-3-319-96145-3_25
external_id:
isi:
- '000491481600025'
file:
- access_level: open_access
checksum: 6dca832f575d6b3f0ea9dff56f579142
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:17:53Z
date_updated: 2020-07-14T12:44:50Z
file_id: '5310'
file_name: IST-2018-1010-v1+1_space-time_interpolants.pdf
file_size: 563710
relation: main_file
file_date_updated: 2020-07-14T12:44:50Z
has_accepted_license: '1'
intvolume: ' 10981'
isi: 1
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 468 - 486
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25F5A88A-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11402-N23
name: Moderne Concurrency Paradigms
publication_identifier:
issn:
- '03029743'
publication_status: published
publisher: Springer
publist_id: '7783'
pubrep_id: '1010'
quality_controlled: '1'
related_material:
record:
- id: '6894'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Space-time interpolants
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 10981
year: '2018'
...
---
_id: '154'
abstract:
- lang: eng
text: We give a lower bound on the ground state energy of a system of two fermions
of one species interacting with two fermions of another species via point interactions.
We show that there is a critical mass ratio m2 ≈ 0.58 such that the system is
stable, i.e., the energy is bounded from below, for m∈[m2,m2−1]. So far it was
not known whether this 2 + 2 system exhibits a stable region at all or whether
the formation of four-body bound states causes an unbounded spectrum for all mass
ratios, similar to the Thomas effect. Our result gives further evidence for the
stability of the more general N + M system.
acknowledgement: Open access funding provided by Austrian Science Fund (FWF).
article_number: '19'
article_processing_charge: No
article_type: original
author:
- first_name: Thomas
full_name: Moser, Thomas
id: 2B5FC9A4-F248-11E8-B48F-1D18A9856A87
last_name: Moser
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Moser T, Seiringer R. Stability of the 2+2 fermionic system with point interactions.
Mathematical Physics Analysis and Geometry. 2018;21(3). doi:10.1007/s11040-018-9275-3
apa: Moser, T., & Seiringer, R. (2018). Stability of the 2+2 fermionic system
with point interactions. Mathematical Physics Analysis and Geometry. Springer.
https://doi.org/10.1007/s11040-018-9275-3
chicago: Moser, Thomas, and Robert Seiringer. “Stability of the 2+2 Fermionic System
with Point Interactions.” Mathematical Physics Analysis and Geometry. Springer,
2018. https://doi.org/10.1007/s11040-018-9275-3.
ieee: T. Moser and R. Seiringer, “Stability of the 2+2 fermionic system with point
interactions,” Mathematical Physics Analysis and Geometry, vol. 21, no.
3. Springer, 2018.
ista: Moser T, Seiringer R. 2018. Stability of the 2+2 fermionic system with point
interactions. Mathematical Physics Analysis and Geometry. 21(3), 19.
mla: Moser, Thomas, and Robert Seiringer. “Stability of the 2+2 Fermionic System
with Point Interactions.” Mathematical Physics Analysis and Geometry, vol.
21, no. 3, 19, Springer, 2018, doi:10.1007/s11040-018-9275-3.
short: T. Moser, R. Seiringer, Mathematical Physics Analysis and Geometry 21 (2018).
date_created: 2018-12-11T11:44:55Z
date_published: 2018-09-01T00:00:00Z
date_updated: 2023-09-19T09:31:15Z
day: '01'
ddc:
- '530'
department:
- _id: RoSe
doi: 10.1007/s11040-018-9275-3
ec_funded: 1
external_id:
isi:
- '000439639700001'
file:
- access_level: open_access
checksum: 411c4db5700d7297c9cd8ebc5dd29091
content_type: application/pdf
creator: dernst
date_created: 2018-12-17T16:49:02Z
date_updated: 2020-07-14T12:45:01Z
file_id: '5729'
file_name: 2018_MathPhysics_Moser.pdf
file_size: 496973
relation: main_file
file_date_updated: 2020-07-14T12:45:01Z
has_accepted_license: '1'
intvolume: ' 21'
isi: 1
issue: '3'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
project:
- _id: 25C6DC12-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '694227'
name: Analysis of quantum many-body systems
- _id: 25C878CE-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P27533_N27
name: Structure of the Excitation Spectrum for Many-Body Quantum Systems
- _id: 3AC91DDA-15DF-11EA-824D-93A3E7B544D1
call_identifier: FWF
name: FWF Open Access Fund
publication: Mathematical Physics Analysis and Geometry
publication_identifier:
eissn:
- '15729656'
issn:
- '13850172'
publication_status: published
publisher: Springer
publist_id: '7767'
quality_controlled: '1'
related_material:
record:
- id: '52'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Stability of the 2+2 fermionic system with point interactions
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 21
year: '2018'
...
---
_id: '5787'
abstract:
- lang: eng
text: "Branching morphogenesis remains a subject of abiding interest. Although
\ much is \r\nknown about the gene regulatory programs and signaling pathways
that operate at \r\nthe cellular scale, it has remained unclear how the macroscopic
features of branched \r\norgans, including their size, network topology and
\ spatial patterning, are encoded. \r\nLately, it has been proposed that,
these features can be explained quantitatively in \r\nseveral organs within a
single unifying framework. Based on large-\r\nscale organ recon\r\n-\r\nstructions
\ and cell lineage tracing, it has been argued that morphogenesis follows
\ \r\nfrom the collective dynamics of sublineage- \r\nrestricted self- \r\nrenewing
progenitor cells, \r\nlocalized at ductal tips, that act cooperatively to drive
a serial process of ductal elon\r\n-\r\ngation and stochastic tip bifurcation.
By correlating differentiation or cell cycle exit \r\nwith proximity to maturing
ducts, this dynamic results in the specification of a com-\r\nplex network of
\ defined density and statistical organization. These results suggest \r\nthat,
for several mammalian tissues, branched epithelial structures develop as a self-
\r\norganized process, reliant upon a strikingly simple, but generic,
\ set of local rules, \r\nwithout recourse to a rigid and deterministic
\ sequence of genetically programmed \r\nevents. Here, we review the basis
of these findings and discuss their implications."
article_processing_charge: No
author:
- first_name: Edouard B
full_name: Hannezo, Edouard B
id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
last_name: Hannezo
orcid: 0000-0001-6005-1561
- first_name: Benjamin D.
full_name: Simons, Benjamin D.
last_name: Simons
citation:
ama: Hannezo EB, Simons BD. Statistical theory of branching morphogenesis. Development
Growth and Differentiation. 2018;60(9):512-521. doi:10.1111/dgd.12570
apa: Hannezo, E. B., & Simons, B. D. (2018). Statistical theory of branching
morphogenesis. Development Growth and Differentiation. Wiley. https://doi.org/10.1111/dgd.12570
chicago: Hannezo, Edouard B, and Benjamin D. Simons. “Statistical Theory of Branching
Morphogenesis.” Development Growth and Differentiation. Wiley, 2018. https://doi.org/10.1111/dgd.12570.
ieee: E. B. Hannezo and B. D. Simons, “Statistical theory of branching morphogenesis,”
Development Growth and Differentiation, vol. 60, no. 9. Wiley, pp. 512–521,
2018.
ista: Hannezo EB, Simons BD. 2018. Statistical theory of branching morphogenesis.
Development Growth and Differentiation. 60(9), 512–521.
mla: Hannezo, Edouard B., and Benjamin D. Simons. “Statistical Theory of Branching
Morphogenesis.” Development Growth and Differentiation, vol. 60, no. 9,
Wiley, 2018, pp. 512–21, doi:10.1111/dgd.12570.
short: E.B. Hannezo, B.D. Simons, Development Growth and Differentiation 60 (2018)
512–521.
date_created: 2018-12-30T22:59:14Z
date_published: 2018-12-09T00:00:00Z
date_updated: 2023-09-19T09:32:49Z
day: '09'
ddc:
- '570'
department:
- _id: EdHa
doi: 10.1111/dgd.12570
external_id:
isi:
- '000453555100002'
file:
- access_level: open_access
checksum: a6d30b0785db902c734a84fecb2eadd9
content_type: application/pdf
creator: dernst
date_created: 2019-02-06T10:40:46Z
date_updated: 2020-07-14T12:47:11Z
file_id: '5933'
file_name: 2018_DevGrowh_Hannezo.pdf
file_size: 1313606
relation: main_file
file_date_updated: 2020-07-14T12:47:11Z
has_accepted_license: '1'
intvolume: ' 60'
isi: 1
issue: '9'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 512-521
publication: Development Growth and Differentiation
publication_identifier:
issn:
- '00121592'
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Statistical theory of branching morphogenesis
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 60
year: '2018'
...
---
_id: '297'
abstract:
- lang: eng
text: Graph games played by two players over finite-state graphs are central in
many problems in computer science. In particular, graph games with ω -regular
winning conditions, specified as parity objectives, which can express properties
such as safety, liveness, fairness, are the basic framework for verification and
synthesis of reactive systems. The decisions for a player at various states of
the graph game are represented as strategies. While the algorithmic problem for
solving graph games with parity objectives has been widely studied, the most prominent
data-structure for strategy representation in graph games has been binary decision
diagrams (BDDs). However, due to the bit-level representation, BDDs do not retain
the inherent flavor of the decisions of strategies, and are notoriously hard to
minimize to obtain succinct representation. In this work we propose decision trees
for strategy representation in graph games. Decision trees retain the flavor of
decisions of strategies and allow entropy-based minimization to obtain succinct
trees. However, decision trees work in settings (e.g., probabilistic models) where
errors are allowed, and overfitting of data is typically avoided. In contrast,
for strategies in graph games no error is allowed, and the decision tree must
represent the entire strategy. We develop new techniques to extend decision trees
to overcome the above obstacles, while retaining the entropy-based techniques
to obtain succinct trees. We have implemented our techniques to extend the existing
decision tree solvers. We present experimental results for problems in reactive
synthesis to show that decision trees provide a much more efficient data-structure
for strategy representation as compared to BDDs.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Tomáš
full_name: Brázdil, Tomáš
last_name: Brázdil
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Jan
full_name: Kretinsky, Jan
id: 44CEF464-F248-11E8-B48F-1D18A9856A87
last_name: Kretinsky
orcid: 0000-0002-8122-2881
- first_name: Viktor
full_name: Toman, Viktor
id: 3AF3DA7C-F248-11E8-B48F-1D18A9856A87
last_name: Toman
orcid: 0000-0001-9036-063X
citation:
ama: 'Brázdil T, Chatterjee K, Kretinsky J, Toman V. Strategy representation by
decision trees in reactive synthesis. In: Vol 10805. Springer; 2018:385-407. doi:10.1007/978-3-319-89960-2_21'
apa: 'Brázdil, T., Chatterjee, K., Kretinsky, J., & Toman, V. (2018). Strategy
representation by decision trees in reactive synthesis (Vol. 10805, pp. 385–407).
Presented at the TACAS 2018: Tools and Algorithms for the Construction and Analysis
of Systems, Thessaloniki, Greece: Springer. https://doi.org/10.1007/978-3-319-89960-2_21'
chicago: Brázdil, Tomáš, Krishnendu Chatterjee, Jan Kretinsky, and Viktor Toman.
“Strategy Representation by Decision Trees in Reactive Synthesis,” 10805:385–407.
Springer, 2018. https://doi.org/10.1007/978-3-319-89960-2_21.
ieee: 'T. Brázdil, K. Chatterjee, J. Kretinsky, and V. Toman, “Strategy representation
by decision trees in reactive synthesis,” presented at the TACAS 2018: Tools and
Algorithms for the Construction and Analysis of Systems, Thessaloniki, Greece,
2018, vol. 10805, pp. 385–407.'
ista: 'Brázdil T, Chatterjee K, Kretinsky J, Toman V. 2018. Strategy representation
by decision trees in reactive synthesis. TACAS 2018: Tools and Algorithms for
the Construction and Analysis of Systems, LNCS, vol. 10805, 385–407.'
mla: Brázdil, Tomáš, et al. Strategy Representation by Decision Trees in Reactive
Synthesis. Vol. 10805, Springer, 2018, pp. 385–407, doi:10.1007/978-3-319-89960-2_21.
short: T. Brázdil, K. Chatterjee, J. Kretinsky, V. Toman, in:, Springer, 2018, pp.
385–407.
conference:
end_date: 2018-04-20
location: Thessaloniki, Greece
name: 'TACAS 2018: Tools and Algorithms for the Construction and Analysis of Systems'
start_date: 2018-04-14
date_created: 2018-12-11T11:45:41Z
date_published: 2018-04-12T00:00:00Z
date_updated: 2023-09-19T09:57:08Z
day: '12'
ddc:
- '000'
department:
- _id: KrCh
- _id: ToHe
doi: 10.1007/978-3-319-89960-2_21
ec_funded: 1
external_id:
isi:
- '000546326300021'
file:
- access_level: open_access
checksum: b13874ffb114932ad9cc2586b7469db4
content_type: application/pdf
creator: dernst
date_created: 2018-12-17T16:29:08Z
date_updated: 2020-07-14T12:45:57Z
file_id: '5723'
file_name: 2018_LNCS_Brazdil.pdf
file_size: 1829940
relation: main_file
file_date_updated: 2020-07-14T12:45:57Z
has_accepted_license: '1'
intvolume: ' 10805'
isi: 1
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 385 - 407
project:
- _id: 25892FC0-B435-11E9-9278-68D0E5697425
grant_number: ICT15-003
name: Efficient Algorithms for Computer Aided Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '665385'
name: International IST Doctoral Program
publication_status: published
publisher: Springer
publist_id: '7584'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Strategy representation by decision trees in reactive synthesis
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 10805
year: '2018'
...
---
_id: '141'
abstract:
- lang: eng
text: 'Given a model and a specification, the fundamental model-checking problem
asks for algorithmic verification of whether the model satisfies the specification.
We consider graphs and Markov decision processes (MDPs), which are fundamental
models for reactive systems. One of the very basic specifications that arise in
verification of reactive systems is the strong fairness (aka Streett) objective.
Given different types of requests and corresponding grants, the objective requires
that for each type, if the request event happens infinitely often, then the corresponding
grant event must also happen infinitely often. All ω -regular objectives can be
expressed as Streett objectives and hence they are canonical in verification.
To handle the state-space explosion, symbolic algorithms are required that operate
on a succinct implicit representation of the system rather than explicitly accessing
the system. While explicit algorithms for graphs and MDPs with Streett objectives
have been widely studied, there has been no improvement of the basic symbolic
algorithms. The worst-case numbers of symbolic steps required for the basic symbolic
algorithms are as follows: quadratic for graphs and cubic for MDPs. In this work
we present the first sub-quadratic symbolic algorithm for graphs with Streett
objectives, and our algorithm is sub-quadratic even for MDPs. Based on our algorithmic
insights we present an implementation of the new symbolic approach and show that
it improves the existing approach on several academic benchmark examples.'
acknowledgement: 'Acknowledgements. K. C. and M. H. are partially supported by the
Vienna Science and Technology Fund (WWTF) grant ICT15-003. K. C. is partially supported
by the Austrian Science Fund (FWF): S11407-N23 (RiSE/SHiNE), and an ERC Start Grant
(279307: Graph Games). V. T. is partially supported by the European Union’s Horizon
2020 research and innovation programme under the Marie Sk lodowska-Curie Grant Agreement
No. 665385.'
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Veronika
full_name: Loitzenbauer, Veronika
last_name: Loitzenbauer
- first_name: Simin
full_name: Oraee, Simin
last_name: Oraee
- first_name: Viktor
full_name: Toman, Viktor
id: 3AF3DA7C-F248-11E8-B48F-1D18A9856A87
last_name: Toman
orcid: 0000-0001-9036-063X
citation:
ama: 'Chatterjee K, Henzinger MH, Loitzenbauer V, Oraee S, Toman V. Symbolic algorithms
for graphs and Markov decision processes with fairness objectives. In: Vol 10982.
Springer; 2018:178-197. doi:10.1007/978-3-319-96142-2_13'
apa: 'Chatterjee, K., Henzinger, M. H., Loitzenbauer, V., Oraee, S., & Toman,
V. (2018). Symbolic algorithms for graphs and Markov decision processes with fairness
objectives (Vol. 10982, pp. 178–197). Presented at the CAV: Computer Aided Verification,
Oxford, United Kingdom: Springer. https://doi.org/10.1007/978-3-319-96142-2_13'
chicago: Chatterjee, Krishnendu, Monika H Henzinger, Veronika Loitzenbauer, Simin
Oraee, and Viktor Toman. “Symbolic Algorithms for Graphs and Markov Decision Processes
with Fairness Objectives,” 10982:178–97. Springer, 2018. https://doi.org/10.1007/978-3-319-96142-2_13.
ieee: 'K. Chatterjee, M. H. Henzinger, V. Loitzenbauer, S. Oraee, and V. Toman,
“Symbolic algorithms for graphs and Markov decision processes with fairness objectives,”
presented at the CAV: Computer Aided Verification, Oxford, United Kingdom, 2018,
vol. 10982, pp. 178–197.'
ista: 'Chatterjee K, Henzinger MH, Loitzenbauer V, Oraee S, Toman V. 2018. Symbolic
algorithms for graphs and Markov decision processes with fairness objectives.
CAV: Computer Aided Verification, LNCS, vol. 10982, 178–197.'
mla: Chatterjee, Krishnendu, et al. Symbolic Algorithms for Graphs and Markov
Decision Processes with Fairness Objectives. Vol. 10982, Springer, 2018, pp.
178–97, doi:10.1007/978-3-319-96142-2_13.
short: K. Chatterjee, M.H. Henzinger, V. Loitzenbauer, S. Oraee, V. Toman, in:,
Springer, 2018, pp. 178–197.
conference:
end_date: 2018-07-17
location: Oxford, United Kingdom
name: 'CAV: Computer Aided Verification'
start_date: 2018-07-14
date_created: 2018-12-11T11:44:51Z
date_published: 2018-07-18T00:00:00Z
date_updated: 2023-09-19T09:59:55Z
day: '18'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1007/978-3-319-96142-2_13
ec_funded: 1
external_id:
isi:
- '000491469700013'
file:
- access_level: open_access
checksum: 1a6ffa4febe8bb8ac28be3adb3eafebc
content_type: application/pdf
creator: dernst
date_created: 2018-12-18T08:52:38Z
date_updated: 2020-07-14T12:44:53Z
file_id: '5737'
file_name: 2018_LNCS_Chatterjee.pdf
file_size: 675606
relation: main_file
file_date_updated: 2020-07-14T12:44:53Z
has_accepted_license: '1'
intvolume: ' 10982'
isi: 1
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 178-197
project:
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 25892FC0-B435-11E9-9278-68D0E5697425
grant_number: ICT15-003
name: Efficient Algorithms for Computer Aided Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '665385'
name: International IST Doctoral Program
publication_status: published
publisher: Springer
publist_id: '7782'
quality_controlled: '1'
related_material:
record:
- id: '10199'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Symbolic algorithms for graphs and Markov decision processes with fairness
objectives
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 10982
year: '2018'
...
---
_id: '298'
abstract:
- lang: eng
text: "Memory-hard functions (MHF) are functions whose evaluation cost is dominated
by memory cost. MHFs are egalitarian, in the sense that evaluating them on dedicated
hardware (like FPGAs or ASICs) is not much cheaper than on off-the-shelf hardware
(like x86 CPUs). MHFs have interesting cryptographic applications, most notably
to password hashing and securing blockchains.\r\n\r\nAlwen and Serbinenko [STOC’15]
define the cumulative memory complexity (cmc) of a function as the sum (over all
time-steps) of the amount of memory required to compute the function. They advocate
that a good MHF must have high cmc. Unlike previous notions, cmc takes into account
that dedicated hardware might exploit amortization and parallelism. Still, cmc
has been critizised as insufficient, as it fails to capture possible time-memory
trade-offs; as memory cost doesn’t scale linearly, functions with the same cmc
could still have very different actual hardware cost.\r\n\r\nIn this work we address
this problem, and introduce the notion of sustained-memory complexity, which requires
that any algorithm evaluating the function must use a large amount of memory for
many steps. We construct functions (in the parallel random oracle model) whose
sustained-memory complexity is almost optimal: our function can be evaluated using
n steps and O(n/log(n)) memory, in each step making one query to the (fixed-input
length) random oracle, while any algorithm that can make arbitrary many parallel
queries to the random oracle, still needs Ω(n/log(n)) memory for Ω(n) steps.\r\n\r\nAs
has been done for various notions (including cmc) before, we reduce the task of
constructing an MHFs with high sustained-memory complexity to proving pebbling
lower bounds on DAGs. Our main technical contribution is the construction is a
family of DAGs on n nodes with constant indegree with high “sustained-space complexity”,
meaning that any parallel black-pebbling strategy requires Ω(n/log(n)) pebbles
for at least Ω(n) steps.\r\n\r\nAlong the way we construct a family of maximally
“depth-robust” DAGs with maximum indegree O(logn) , improving upon the construction
of Mahmoody et al. [ITCS’13] which had maximum indegree O(log2n⋅"
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Joel F
full_name: Alwen, Joel F
id: 2A8DFA8C-F248-11E8-B48F-1D18A9856A87
last_name: Alwen
- first_name: Jeremiah
full_name: Blocki, Jeremiah
last_name: Blocki
- first_name: Krzysztof Z
full_name: Pietrzak, Krzysztof Z
id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
last_name: Pietrzak
orcid: 0000-0002-9139-1654
citation:
ama: 'Alwen JF, Blocki J, Pietrzak KZ. Sustained space complexity. In: Vol 10821.
Springer; 2018:99-130. doi:10.1007/978-3-319-78375-8_4'
apa: 'Alwen, J. F., Blocki, J., & Pietrzak, K. Z. (2018). Sustained space complexity
(Vol. 10821, pp. 99–130). Presented at the Eurocrypt 2018: Advances in Cryptology,
Tel Aviv, Israel: Springer. https://doi.org/10.1007/978-3-319-78375-8_4'
chicago: Alwen, Joel F, Jeremiah Blocki, and Krzysztof Z Pietrzak. “Sustained Space
Complexity,” 10821:99–130. Springer, 2018. https://doi.org/10.1007/978-3-319-78375-8_4.
ieee: 'J. F. Alwen, J. Blocki, and K. Z. Pietrzak, “Sustained space complexity,”
presented at the Eurocrypt 2018: Advances in Cryptology, Tel Aviv, Israel, 2018,
vol. 10821, pp. 99–130.'
ista: 'Alwen JF, Blocki J, Pietrzak KZ. 2018. Sustained space complexity. Eurocrypt
2018: Advances in Cryptology, LNCS, vol. 10821, 99–130.'
mla: Alwen, Joel F., et al. Sustained Space Complexity. Vol. 10821, Springer,
2018, pp. 99–130, doi:10.1007/978-3-319-78375-8_4.
short: J.F. Alwen, J. Blocki, K.Z. Pietrzak, in:, Springer, 2018, pp. 99–130.
conference:
end_date: 2018-05-03
location: Tel Aviv, Israel
name: 'Eurocrypt 2018: Advances in Cryptology'
start_date: 2018-04-29
date_created: 2018-12-11T11:45:41Z
date_published: 2018-03-31T00:00:00Z
date_updated: 2023-09-19T09:59:30Z
day: '31'
department:
- _id: KrPi
doi: 10.1007/978-3-319-78375-8_4
ec_funded: 1
external_id:
arxiv:
- '1705.05313'
isi:
- '000517098700004'
intvolume: ' 10821'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1705.05313
month: '03'
oa: 1
oa_version: Preprint
page: 99 - 130
project:
- _id: 258AA5B2-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '682815'
name: Teaching Old Crypto New Tricks
publication_status: published
publisher: Springer
publist_id: '7583'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Sustained space complexity
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 10821
year: '2018'
...
---
_id: '36'
abstract:
- lang: eng
text: Wheat (Triticum ssp.) is one of the most important human food sources. However,
this crop is very sensitive to temperature changes. Specifically, processes during
wheat leaf, flower, and seed development and photosynthesis, which all contribute
to the yield of this crop, are affected by high temperature. While this has to
some extent been investigated on physiological, developmental, and molecular levels,
very little is known about early signalling events associated with an increase
in temperature. Phosphorylation-mediated signalling mechanisms, which are quick
and dynamic, are associated with plant growth and development, also under abiotic
stress conditions. Therefore, we probed the impact of a short-term and mild increase
in temperature on the wheat leaf and spikelet phosphoproteome. In total, 3822
(containing 5178 phosphosites) and 5581 phosphopeptides (containing 7023 phosphosites)
were identified in leaf and spikelet samples, respectively. Following statistical
analysis, the resulting data set provides the scientific community with a first
large-scale plant phosphoproteome under the control of higher ambient temperature.
This community resource on the high temperature-mediated wheat phosphoproteome
will be valuable for future studies. Our analyses also revealed a core set of
common proteins between leaf and spikelet, suggesting some level of conserved
regulatory mechanisms. Furthermore, we observed temperature-regulated interconversion
of phosphoforms, which probably impacts protein activity.
acknowledgement: TZ is supported by a grant from the Chinese Scholarship Council.
article_processing_charge: No
author:
- first_name: Lam
full_name: Vu, Lam
last_name: Vu
- first_name: Tingting
full_name: Zhu, Tingting
last_name: Zhu
- first_name: Inge
full_name: Verstraeten, Inge
id: 362BF7FE-F248-11E8-B48F-1D18A9856A87
last_name: Verstraeten
orcid: 0000-0001-7241-2328
- first_name: Brigitte
full_name: Van De Cotte, Brigitte
last_name: Van De Cotte
- first_name: Kris
full_name: Gevaert, Kris
last_name: Gevaert
- first_name: Ive
full_name: De Smet, Ive
last_name: De Smet
citation:
ama: Vu L, Zhu T, Verstraeten I, Van De Cotte B, Gevaert K, De Smet I. Temperature-induced
changes in the wheat phosphoproteome reveal temperature-regulated interconversion
of phosphoforms. Journal of Experimental Botany. 2018;69(19):4609-4624.
doi:10.1093/jxb/ery204
apa: Vu, L., Zhu, T., Verstraeten, I., Van De Cotte, B., Gevaert, K., & De Smet,
I. (2018). Temperature-induced changes in the wheat phosphoproteome reveal temperature-regulated
interconversion of phosphoforms. Journal of Experimental Botany. Oxford
University Press. https://doi.org/10.1093/jxb/ery204
chicago: Vu, Lam, Tingting Zhu, Inge Verstraeten, Brigitte Van De Cotte, Kris Gevaert,
and Ive De Smet. “Temperature-Induced Changes in the Wheat Phosphoproteome Reveal
Temperature-Regulated Interconversion of Phosphoforms.” Journal of Experimental
Botany. Oxford University Press, 2018. https://doi.org/10.1093/jxb/ery204.
ieee: L. Vu, T. Zhu, I. Verstraeten, B. Van De Cotte, K. Gevaert, and I. De Smet,
“Temperature-induced changes in the wheat phosphoproteome reveal temperature-regulated
interconversion of phosphoforms,” Journal of Experimental Botany, vol.
69, no. 19. Oxford University Press, pp. 4609–4624, 2018.
ista: Vu L, Zhu T, Verstraeten I, Van De Cotte B, Gevaert K, De Smet I. 2018. Temperature-induced
changes in the wheat phosphoproteome reveal temperature-regulated interconversion
of phosphoforms. Journal of Experimental Botany. 69(19), 4609–4624.
mla: Vu, Lam, et al. “Temperature-Induced Changes in the Wheat Phosphoproteome Reveal
Temperature-Regulated Interconversion of Phosphoforms.” Journal of Experimental
Botany, vol. 69, no. 19, Oxford University Press, 2018, pp. 4609–24, doi:10.1093/jxb/ery204.
short: L. Vu, T. Zhu, I. Verstraeten, B. Van De Cotte, K. Gevaert, I. De Smet, Journal
of Experimental Botany 69 (2018) 4609–4624.
date_created: 2018-12-11T11:44:17Z
date_published: 2018-08-31T00:00:00Z
date_updated: 2023-09-19T10:00:46Z
day: '31'
ddc:
- '581'
department:
- _id: JiFr
doi: 10.1093/jxb/ery204
external_id:
isi:
- '000443568700010'
file:
- access_level: open_access
checksum: 34cb0a1611588b75bd6f4913fb4e30f1
content_type: application/pdf
creator: dernst
date_created: 2018-12-18T09:47:51Z
date_updated: 2020-07-14T12:46:13Z
file_id: '5741'
file_name: 2018_JournalExperimBotany_Vu.pdf
file_size: 3359316
relation: main_file
file_date_updated: 2020-07-14T12:46:13Z
has_accepted_license: '1'
intvolume: ' 69'
isi: 1
issue: '19'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 4609 - 4624
publication: Journal of Experimental Botany
publication_status: published
publisher: Oxford University Press
publist_id: '8019'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Temperature-induced changes in the wheat phosphoproteome reveal temperature-regulated
interconversion of phosphoforms
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 69
year: '2018'
...
---
_id: '326'
abstract:
- lang: eng
text: Three-dimensional (3D) super-resolution microscopy technique structured illumination
microscopy (SIM) imaging of dendritic spines along the dendrite has not been previously
performed in fixed tissues, mainly due to deterioration of the stripe pattern
of the excitation laser induced by light scattering and optical aberrations. To
address this issue and solve these optical problems, we applied a novel clearing
reagent, LUCID, to fixed brains. In SIM imaging, the penetration depth and the
spatial resolution were improved in LUCID-treated slices, and 160-nm spatial resolution
was obtained in a large portion of the imaging volume on a single apical dendrite.
Furthermore, in a morphological analysis of spine heads of layer V pyramidal neurons
(L5PNs) in the medial prefrontal cortex (mPFC) of chronic dexamethasone (Dex)-treated
mice, SIM imaging revealed an altered distribution of spine forms that could not
be detected by high-NA confocal imaging. Thus, super-resolution SIM imaging represents
a promising high-throughput method for revealing spine morphologies in single
dendrites.
acknowledged_ssus:
- _id: EM-Fac
article_processing_charge: No
author:
- first_name: Kazuaki
full_name: Sawada, Kazuaki
last_name: Sawada
- first_name: Ryosuke
full_name: Kawakami, Ryosuke
last_name: Kawakami
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Tomomi
full_name: Nemoto, Tomomi
last_name: Nemoto
citation:
ama: Sawada K, Kawakami R, Shigemoto R, Nemoto T. Super resolution structural analysis
of dendritic spines using three-dimensional structured illumination microscopy
in cleared mouse brain slices. European Journal of Neuroscience. 2018;47(9):1033-1042.
doi:10.1111/ejn.13901
apa: Sawada, K., Kawakami, R., Shigemoto, R., & Nemoto, T. (2018). Super resolution
structural analysis of dendritic spines using three-dimensional structured illumination
microscopy in cleared mouse brain slices. European Journal of Neuroscience.
Wiley. https://doi.org/10.1111/ejn.13901
chicago: Sawada, Kazuaki, Ryosuke Kawakami, Ryuichi Shigemoto, and Tomomi Nemoto.
“Super Resolution Structural Analysis of Dendritic Spines Using Three-Dimensional
Structured Illumination Microscopy in Cleared Mouse Brain Slices.” European
Journal of Neuroscience. Wiley, 2018. https://doi.org/10.1111/ejn.13901.
ieee: K. Sawada, R. Kawakami, R. Shigemoto, and T. Nemoto, “Super resolution structural
analysis of dendritic spines using three-dimensional structured illumination microscopy
in cleared mouse brain slices,” European Journal of Neuroscience, vol.
47, no. 9. Wiley, pp. 1033–1042, 2018.
ista: Sawada K, Kawakami R, Shigemoto R, Nemoto T. 2018. Super resolution structural
analysis of dendritic spines using three-dimensional structured illumination microscopy
in cleared mouse brain slices. European Journal of Neuroscience. 47(9), 1033–1042.
mla: Sawada, Kazuaki, et al. “Super Resolution Structural Analysis of Dendritic
Spines Using Three-Dimensional Structured Illumination Microscopy in Cleared Mouse
Brain Slices.” European Journal of Neuroscience, vol. 47, no. 9, Wiley,
2018, pp. 1033–42, doi:10.1111/ejn.13901.
short: K. Sawada, R. Kawakami, R. Shigemoto, T. Nemoto, European Journal of Neuroscience
47 (2018) 1033–1042.
date_created: 2018-12-11T11:45:50Z
date_published: 2018-03-07T00:00:00Z
date_updated: 2023-09-19T09:58:40Z
day: '07'
ddc:
- '570'
department:
- _id: RySh
doi: 10.1111/ejn.13901
external_id:
isi:
- '000431496400001'
file:
- access_level: open_access
checksum: 98e901d8229e44aa8f3b51d248dedd09
content_type: application/pdf
creator: dernst
date_created: 2018-12-17T16:16:50Z
date_updated: 2020-07-14T12:46:06Z
file_id: '5721'
file_name: 2018_EJN_Sawada.pdf
file_size: 4850261
relation: main_file
file_date_updated: 2020-07-14T12:46:06Z
has_accepted_license: '1'
intvolume: ' 47'
isi: 1
issue: '9'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '03'
oa: 1
oa_version: Published Version
page: 1033 - 1042
publication: European Journal of Neuroscience
publication_status: published
publisher: Wiley
publist_id: '7539'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Super resolution structural analysis of dendritic spines using three-dimensional
structured illumination microscopy in cleared mouse brain slices
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 47
year: '2018'
...
---
_id: '5770'
abstract:
- lang: eng
text: Retroviruses assemble and bud from infected cells in an immature form and
require proteolytic maturation for infectivity. The CA (capsid) domains of the
Gag polyproteins assemble a protein lattice as a truncated sphere in the immature
virion. Proteolytic cleavage of Gag induces dramatic structural rearrangements;
a subset of cleaved CA subsequently assembles into the mature core, whose architecture
varies among retroviruses. Murine leukemia virus (MLV) is the prototypical γ-retrovirus
and serves as the basis of retroviral vectors, but the structure of the MLV CA
layer is unknown. Here we have combined X-ray crystallography with cryoelectron
tomography to determine the structures of immature and mature MLV CA layers within
authentic viral particles. This reveals the structural changes associated with
maturation, and, by comparison with HIV-1, uncovers conserved and variable features.
In contrast to HIV-1, most MLV CA is used for assembly of the mature core, which
adopts variable, multilayered morphologies and does not form a closed structure.
Unlike in HIV-1, there is similarity between protein–protein interfaces in the
immature MLV CA layer and those in the mature CA layer, and structural maturation
of MLV could be achieved through domain rotations that largely maintain hexameric
interactions. Nevertheless, the dramatic architectural change on maturation indicates
that extensive disassembly and reassembly are required for mature core growth.
The core morphology suggests that wrapping of the genome in CA sheets may be sufficient
to protect the MLV ribonucleoprotein during cell entry.
article_processing_charge: No
author:
- first_name: Kun
full_name: Qu, Kun
last_name: Qu
- first_name: Bärbel
full_name: Glass, Bärbel
last_name: Glass
- first_name: Michal
full_name: Doležal, Michal
last_name: Doležal
- first_name: Florian
full_name: Schur, Florian
id: 48AD8942-F248-11E8-B48F-1D18A9856A87
last_name: Schur
orcid: 0000-0003-4790-8078
- first_name: Brice
full_name: Murciano, Brice
last_name: Murciano
- first_name: Alan
full_name: Rein, Alan
last_name: Rein
- first_name: Michaela
full_name: Rumlová, Michaela
last_name: Rumlová
- first_name: Tomáš
full_name: Ruml, Tomáš
last_name: Ruml
- first_name: Hans-Georg
full_name: Kräusslich, Hans-Georg
last_name: Kräusslich
- first_name: John A. G.
full_name: Briggs, John A. G.
last_name: Briggs
citation:
ama: Qu K, Glass B, Doležal M, et al. Structure and architecture of immature and
mature murine leukemia virus capsids. Proceedings of the National Academy of
Sciences. 2018;115(50):E11751-E11760. doi:10.1073/pnas.1811580115
apa: Qu, K., Glass, B., Doležal, M., Schur, F. K., Murciano, B., Rein, A., … Briggs,
J. A. G. (2018). Structure and architecture of immature and mature murine leukemia
virus capsids. Proceedings of the National Academy of Sciences. Proceedings
of the National Academy of Sciences. https://doi.org/10.1073/pnas.1811580115
chicago: Qu, Kun, Bärbel Glass, Michal Doležal, Florian KM Schur, Brice Murciano,
Alan Rein, Michaela Rumlová, Tomáš Ruml, Hans-Georg Kräusslich, and John A. G.
Briggs. “Structure and Architecture of Immature and Mature Murine Leukemia Virus
Capsids.” Proceedings of the National Academy of Sciences. Proceedings
of the National Academy of Sciences, 2018. https://doi.org/10.1073/pnas.1811580115.
ieee: K. Qu et al., “Structure and architecture of immature and mature murine
leukemia virus capsids,” Proceedings of the National Academy of Sciences,
vol. 115, no. 50. Proceedings of the National Academy of Sciences, pp. E11751–E11760,
2018.
ista: Qu K, Glass B, Doležal M, Schur FK, Murciano B, Rein A, Rumlová M, Ruml T,
Kräusslich H-G, Briggs JAG. 2018. Structure and architecture of immature and mature
murine leukemia virus capsids. Proceedings of the National Academy of Sciences.
115(50), E11751–E11760.
mla: Qu, Kun, et al. “Structure and Architecture of Immature and Mature Murine Leukemia
Virus Capsids.” Proceedings of the National Academy of Sciences, vol. 115,
no. 50, Proceedings of the National Academy of Sciences, 2018, pp. E11751–60,
doi:10.1073/pnas.1811580115.
short: K. Qu, B. Glass, M. Doležal, F.K. Schur, B. Murciano, A. Rein, M. Rumlová,
T. Ruml, H.-G. Kräusslich, J.A.G. Briggs, Proceedings of the National Academy
of Sciences 115 (2018) E11751–E11760.
date_created: 2018-12-20T21:09:37Z
date_published: 2018-12-11T00:00:00Z
date_updated: 2023-09-19T09:57:45Z
day: '11'
department:
- _id: FlSc
doi: 10.1073/pnas.1811580115
external_id:
isi:
- '000452866000022'
pmid:
- '30478053'
intvolume: ' 115'
isi: 1
issue: '50'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pubmed/30478053
month: '12'
oa: 1
oa_version: Submitted Version
page: E11751-E11760
pmid: 1
publication: Proceedings of the National Academy of Sciences
publication_identifier:
issn:
- '00278424'
publication_status: published
publisher: Proceedings of the National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Structure and architecture of immature and mature murine leukemia virus capsids
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 115
year: '2018'
...
---
_id: '608'
abstract:
- lang: eng
text: Synthesis is the automated construction of a system from its specification.
In real life, hardware and software systems are rarely constructed from scratch.
Rather, a system is typically constructed from a library of components. Lustig
and Vardi formalized this intuition and studied LTL synthesis from component libraries.
In real life, designers seek optimal systems. In this paper we add optimality
considerations to the setting. We distinguish between quality considerations (for
example, size - the smaller a system is, the better it is), and pricing (for example,
the payment to the company who manufactured the component). We study the problem
of designing systems with minimal quality-cost and price. A key point is that
while the quality cost is individual - the choices of a designer are independent
of choices made by other designers that use the same library, pricing gives rise
to a resource-allocation game - designers that use the same component share its
price, with the share being proportional to the number of uses (a component can
be used several times in a design). We study both closed and open settings, and
in both we solve the problem of finding an optimal design. In a setting with multiple
designers, we also study the game-theoretic problems of the induced resource-allocation
game.
article_processing_charge: No
article_type: original
author:
- first_name: Guy
full_name: Avni, Guy
id: 463C8BC2-F248-11E8-B48F-1D18A9856A87
last_name: Avni
orcid: 0000-0001-5588-8287
- first_name: Orna
full_name: Kupferman, Orna
last_name: Kupferman
citation:
ama: Avni G, Kupferman O. Synthesis from component libraries with costs. Theoretical
Computer Science. 2018;712:50-72. doi:10.1016/j.tcs.2017.11.001
apa: Avni, G., & Kupferman, O. (2018). Synthesis from component libraries with
costs. Theoretical Computer Science. Elsevier. https://doi.org/10.1016/j.tcs.2017.11.001
chicago: Avni, Guy, and Orna Kupferman. “Synthesis from Component Libraries with
Costs.” Theoretical Computer Science. Elsevier, 2018. https://doi.org/10.1016/j.tcs.2017.11.001.
ieee: G. Avni and O. Kupferman, “Synthesis from component libraries with costs,”
Theoretical Computer Science, vol. 712. Elsevier, pp. 50–72, 2018.
ista: Avni G, Kupferman O. 2018. Synthesis from component libraries with costs.
Theoretical Computer Science. 712, 50–72.
mla: Avni, Guy, and Orna Kupferman. “Synthesis from Component Libraries with Costs.”
Theoretical Computer Science, vol. 712, Elsevier, 2018, pp. 50–72, doi:10.1016/j.tcs.2017.11.001.
short: G. Avni, O. Kupferman, Theoretical Computer Science 712 (2018) 50–72.
date_created: 2018-12-11T11:47:28Z
date_published: 2018-02-15T00:00:00Z
date_updated: 2023-09-19T10:00:21Z
day: '15'
department:
- _id: ToHe
doi: 10.1016/j.tcs.2017.11.001
ec_funded: 1
external_id:
isi:
- '000424959200003'
intvolume: ' 712'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.636.4529
month: '02'
oa: 1
oa_version: Published Version
page: 50 - 72
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
publication: Theoretical Computer Science
publication_status: published
publisher: Elsevier
publist_id: '7197'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Synthesis from component libraries with costs
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 712
year: '2018'
...
---
_id: '705'
abstract:
- lang: eng
text: Although dopamine receptors D1 and D2 play key roles in hippocampal function,
their synaptic localization within the hippocampus has not been fully elucidated.
In order to understand precise functions of pre- or postsynaptic dopamine receptors
(DRs), the development of protocols to differentiate pre- and postsynaptic DRs
is essential. So far, most studies on determination and quantification of DRs
did not discriminate between subsynaptic localization. Therefore, the aim of the
study was to generate a robust workflow for the localization of DRs. This work
provides the basis for future work on hippocampal DRs, in light that DRs may have
different functions at pre- or postsynaptic sites. Synaptosomes from rat hippocampi
isolated by a sucrose gradient protocol were prepared for super-resolution direct
stochastic optical reconstruction microscopy (dSTORM) using Bassoon as a presynaptic
zone and Homer1 as postsynaptic density marker. Direct labeling of primary validated
antibodies against dopamine receptors D1 (D1R) and D2 (D2R) with Alexa Fluor 594
enabled unequivocal assignment of D1R and D2R to both, pre- and postsynaptic sites.
D1R immunoreactivity clusters were observed within the presynaptic active zone
as well as at perisynaptic sites at the edge of the presynaptic active zone. The
results may be useful for the interpretation of previous studies and the design
of future work on DRs in the hippocampus. Moreover, the reduction of the complexity
of brain tissue by the use of synaptosomal preparations and dSTORM technology
may represent a useful tool for synaptic localization of brain proteins.
article_processing_charge: No
author:
- first_name: Andras
full_name: Miklosi, Andras
last_name: Miklosi
- first_name: Giorgia
full_name: Del Favero, Giorgia
last_name: Del Favero
- first_name: Tanja
full_name: Bulat, Tanja
last_name: Bulat
- first_name: Harald
full_name: Höger, Harald
last_name: Höger
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Doris
full_name: Marko, Doris
last_name: Marko
- first_name: Gert
full_name: Lubec, Gert
last_name: Lubec
citation:
ama: Miklosi A, Del Favero G, Bulat T, et al. Super resolution microscopical localization
of dopamine receptors 1 and 2 in rat hippocampal synaptosomes. Molecular Neurobiology.
2018;55(6):4857 – 4869. doi:10.1007/s12035-017-0688-y
apa: Miklosi, A., Del Favero, G., Bulat, T., Höger, H., Shigemoto, R., Marko, D.,
& Lubec, G. (2018). Super resolution microscopical localization of dopamine
receptors 1 and 2 in rat hippocampal synaptosomes. Molecular Neurobiology.
Springer. https://doi.org/10.1007/s12035-017-0688-y
chicago: Miklosi, Andras, Giorgia Del Favero, Tanja Bulat, Harald Höger, Ryuichi
Shigemoto, Doris Marko, and Gert Lubec. “Super Resolution Microscopical Localization
of Dopamine Receptors 1 and 2 in Rat Hippocampal Synaptosomes.” Molecular Neurobiology.
Springer, 2018. https://doi.org/10.1007/s12035-017-0688-y.
ieee: A. Miklosi et al., “Super resolution microscopical localization of
dopamine receptors 1 and 2 in rat hippocampal synaptosomes,” Molecular Neurobiology,
vol. 55, no. 6. Springer, pp. 4857 – 4869, 2018.
ista: Miklosi A, Del Favero G, Bulat T, Höger H, Shigemoto R, Marko D, Lubec G.
2018. Super resolution microscopical localization of dopamine receptors 1 and
2 in rat hippocampal synaptosomes. Molecular Neurobiology. 55(6), 4857 – 4869.
mla: Miklosi, Andras, et al. “Super Resolution Microscopical Localization of Dopamine
Receptors 1 and 2 in Rat Hippocampal Synaptosomes.” Molecular Neurobiology,
vol. 55, no. 6, Springer, 2018, pp. 4857 – 4869, doi:10.1007/s12035-017-0688-y.
short: A. Miklosi, G. Del Favero, T. Bulat, H. Höger, R. Shigemoto, D. Marko, G.
Lubec, Molecular Neurobiology 55 (2018) 4857 – 4869.
date_created: 2018-12-11T11:48:02Z
date_published: 2018-06-01T00:00:00Z
date_updated: 2023-09-19T09:58:11Z
day: '01'
department:
- _id: RySh
doi: 10.1007/s12035-017-0688-y
external_id:
isi:
- '000431991500025'
intvolume: ' 55'
isi: 1
issue: '6'
language:
- iso: eng
month: '06'
oa_version: None
page: 4857 – 4869
publication: Molecular Neurobiology
publication_status: published
publisher: Springer
publist_id: '6991'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Super resolution microscopical localization of dopamine receptors 1 and 2 in
rat hippocampal synaptosomes
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 55
year: '2018'
...
---
_id: '148'
abstract:
- lang: eng
text: 'Land plants evolved from charophytic algae, among which Charophyceae possess
the most complex body plans. We present the genome of Chara braunii; comparison
of the genome to those of land plants identified evolutionary novelties for plant
terrestrialization and land plant heritage genes. C. braunii employs unique xylan
synthases for cell wall biosynthesis, a phragmoplast (cell separation) mechanism
similar to that of land plants, and many phytohormones. C. braunii plastids are
controlled via land-plant-like retrograde signaling, and transcriptional regulation
is more elaborate than in other algae. The morphological complexity of this organism
may result from expanded gene families, with three cases of particular note: genes
effecting tolerance to reactive oxygen species (ROS), LysM receptor-like kinases,
and transcription factors (TFs). Transcriptomic analysis of sexual reproductive
structures reveals intricate control by TFs, activity of the ROS gene network,
and the ancestral use of plant-like storage and stress protection proteins in
the zygote.'
acknowledgement: In-Data-Review
article_processing_charge: No
author:
- first_name: Tomoaki
full_name: Nishiyama, Tomoaki
last_name: Nishiyama
- first_name: Hidetoshi
full_name: Sakayama, Hidetoshi
last_name: Sakayama
- first_name: Jan
full_name: De Vries, Jan
last_name: De Vries
- first_name: Henrik
full_name: Buschmann, Henrik
last_name: Buschmann
- first_name: Denis
full_name: Saint Marcoux, Denis
last_name: Saint Marcoux
- first_name: Kristian
full_name: Ullrich, Kristian
last_name: Ullrich
- first_name: Fabian
full_name: Haas, Fabian
last_name: Haas
- first_name: Lisa
full_name: Vanderstraeten, Lisa
last_name: Vanderstraeten
- first_name: Dirk
full_name: Becker, Dirk
last_name: Becker
- first_name: Daniel
full_name: Lang, Daniel
last_name: Lang
- first_name: Stanislav
full_name: Vosolsobě, Stanislav
last_name: Vosolsobě
- first_name: Stephane
full_name: Rombauts, Stephane
last_name: Rombauts
- first_name: Per
full_name: Wilhelmsson, Per
last_name: Wilhelmsson
- first_name: Philipp
full_name: Janitza, Philipp
last_name: Janitza
- first_name: Ramona
full_name: Kern, Ramona
last_name: Kern
- first_name: Alexander
full_name: Heyl, Alexander
last_name: Heyl
- first_name: Florian
full_name: Rümpler, Florian
last_name: Rümpler
- first_name: Luz
full_name: Calderón Villalobos, Luz
last_name: Calderón Villalobos
- first_name: John
full_name: Clay, John
last_name: Clay
- first_name: Roman
full_name: Skokan, Roman
last_name: Skokan
- first_name: Atsushi
full_name: Toyoda, Atsushi
last_name: Toyoda
- first_name: Yutaka
full_name: Suzuki, Yutaka
last_name: Suzuki
- first_name: Hiroshi
full_name: Kagoshima, Hiroshi
last_name: Kagoshima
- first_name: Elio
full_name: Schijlen, Elio
last_name: Schijlen
- first_name: Navindra
full_name: Tajeshwar, Navindra
last_name: Tajeshwar
- first_name: Bruno
full_name: Catarino, Bruno
last_name: Catarino
- first_name: Alexander
full_name: Hetherington, Alexander
last_name: Hetherington
- first_name: Assia
full_name: Saltykova, Assia
last_name: Saltykova
- first_name: Clemence
full_name: Bonnot, Clemence
last_name: Bonnot
- first_name: Holger
full_name: Breuninger, Holger
last_name: Breuninger
- first_name: Aikaterini
full_name: Symeonidi, Aikaterini
last_name: Symeonidi
- first_name: Guru
full_name: Radhakrishnan, Guru
last_name: Radhakrishnan
- first_name: Filip
full_name: Van Nieuwerburgh, Filip
last_name: Van Nieuwerburgh
- first_name: Dieter
full_name: Deforce, Dieter
last_name: Deforce
- first_name: Caren
full_name: Chang, Caren
last_name: Chang
- first_name: Kenneth
full_name: Karol, Kenneth
last_name: Karol
- first_name: Rainer
full_name: Hedrich, Rainer
last_name: Hedrich
- first_name: Peter
full_name: Ulvskov, Peter
last_name: Ulvskov
- first_name: Gernot
full_name: Glöckner, Gernot
last_name: Glöckner
- first_name: Charles
full_name: Delwiche, Charles
last_name: Delwiche
- first_name: Jan
full_name: Petrášek, Jan
last_name: Petrášek
- first_name: Yves
full_name: Van De Peer, Yves
last_name: Van De Peer
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Mary
full_name: Beilby, Mary
last_name: Beilby
- first_name: Liam
full_name: Dolan, Liam
last_name: Dolan
- first_name: Yuji
full_name: Kohara, Yuji
last_name: Kohara
- first_name: Sumio
full_name: Sugano, Sumio
last_name: Sugano
- first_name: Asao
full_name: Fujiyama, Asao
last_name: Fujiyama
- first_name: Pierre Marc
full_name: Delaux, Pierre Marc
last_name: Delaux
- first_name: Marcel
full_name: Quint, Marcel
last_name: Quint
- first_name: Gunter
full_name: Theissen, Gunter
last_name: Theissen
- first_name: Martin
full_name: Hagemann, Martin
last_name: Hagemann
- first_name: Jesper
full_name: Harholt, Jesper
last_name: Harholt
- first_name: Christophe
full_name: Dunand, Christophe
last_name: Dunand
- first_name: Sabine
full_name: Zachgo, Sabine
last_name: Zachgo
- first_name: Jane
full_name: Langdale, Jane
last_name: Langdale
- first_name: Florian
full_name: Maumus, Florian
last_name: Maumus
- first_name: Dominique
full_name: Van Der Straeten, Dominique
last_name: Van Der Straeten
- first_name: Sven B
full_name: Gould, Sven B
last_name: Gould
- first_name: Stefan
full_name: Rensing, Stefan
last_name: Rensing
citation:
ama: 'Nishiyama T, Sakayama H, De Vries J, et al. The Chara genome: Secondary complexity
and implications for plant terrestrialization. Cell. 2018;174(2):448-464.e24.
doi:10.1016/j.cell.2018.06.033'
apa: 'Nishiyama, T., Sakayama, H., De Vries, J., Buschmann, H., Saint Marcoux, D.,
Ullrich, K., … Rensing, S. (2018). The Chara genome: Secondary complexity and
implications for plant terrestrialization. Cell. Cell Press. https://doi.org/10.1016/j.cell.2018.06.033'
chicago: 'Nishiyama, Tomoaki, Hidetoshi Sakayama, Jan De Vries, Henrik Buschmann,
Denis Saint Marcoux, Kristian Ullrich, Fabian Haas, et al. “The Chara Genome:
Secondary Complexity and Implications for Plant Terrestrialization.” Cell.
Cell Press, 2018. https://doi.org/10.1016/j.cell.2018.06.033.'
ieee: 'T. Nishiyama et al., “The Chara genome: Secondary complexity and implications
for plant terrestrialization,” Cell, vol. 174, no. 2. Cell Press, p. 448–464.e24,
2018.'
ista: 'Nishiyama T, Sakayama H, De Vries J, Buschmann H, Saint Marcoux D, Ullrich
K, Haas F, Vanderstraeten L, Becker D, Lang D, Vosolsobě S, Rombauts S, Wilhelmsson
P, Janitza P, Kern R, Heyl A, Rümpler F, Calderón Villalobos L, Clay J, Skokan
R, Toyoda A, Suzuki Y, Kagoshima H, Schijlen E, Tajeshwar N, Catarino B, Hetherington
A, Saltykova A, Bonnot C, Breuninger H, Symeonidi A, Radhakrishnan G, Van Nieuwerburgh
F, Deforce D, Chang C, Karol K, Hedrich R, Ulvskov P, Glöckner G, Delwiche C,
Petrášek J, Van De Peer Y, Friml J, Beilby M, Dolan L, Kohara Y, Sugano S, Fujiyama
A, Delaux PM, Quint M, Theissen G, Hagemann M, Harholt J, Dunand C, Zachgo S,
Langdale J, Maumus F, Van Der Straeten D, Gould SB, Rensing S. 2018. The Chara
genome: Secondary complexity and implications for plant terrestrialization. Cell.
174(2), 448–464.e24.'
mla: 'Nishiyama, Tomoaki, et al. “The Chara Genome: Secondary Complexity and Implications
for Plant Terrestrialization.” Cell, vol. 174, no. 2, Cell Press, 2018,
p. 448–464.e24, doi:10.1016/j.cell.2018.06.033.'
short: T. Nishiyama, H. Sakayama, J. De Vries, H. Buschmann, D. Saint Marcoux, K.
Ullrich, F. Haas, L. Vanderstraeten, D. Becker, D. Lang, S. Vosolsobě, S. Rombauts,
P. Wilhelmsson, P. Janitza, R. Kern, A. Heyl, F. Rümpler, L. Calderón Villalobos,
J. Clay, R. Skokan, A. Toyoda, Y. Suzuki, H. Kagoshima, E. Schijlen, N. Tajeshwar,
B. Catarino, A. Hetherington, A. Saltykova, C. Bonnot, H. Breuninger, A. Symeonidi,
G. Radhakrishnan, F. Van Nieuwerburgh, D. Deforce, C. Chang, K. Karol, R. Hedrich,
P. Ulvskov, G. Glöckner, C. Delwiche, J. Petrášek, Y. Van De Peer, J. Friml, M.
Beilby, L. Dolan, Y. Kohara, S. Sugano, A. Fujiyama, P.M. Delaux, M. Quint, G.
Theissen, M. Hagemann, J. Harholt, C. Dunand, S. Zachgo, J. Langdale, F. Maumus,
D. Van Der Straeten, S.B. Gould, S. Rensing, Cell 174 (2018) 448–464.e24.
date_created: 2018-12-11T11:44:53Z
date_published: 2018-07-12T00:00:00Z
date_updated: 2023-09-19T10:02:47Z
day: '12'
department:
- _id: JiFr
doi: 10.1016/j.cell.2018.06.033
ec_funded: 1
external_id:
isi:
- '000438482800019'
pmid:
- '30007417'
intvolume: ' 174'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pubmed/30007417
month: '07'
oa: 1
oa_version: Published Version
page: 448 - 464.e24
pmid: 1
project:
- _id: 261099A6-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742985'
name: Tracing Evolution of Auxin Transport and Polarity in Plants
publication: Cell
publication_status: published
publisher: Cell Press
publist_id: '7774'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The Chara genome: Secondary complexity and implications for plant terrestrialization'
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 174
year: '2018'
...
---
_id: '403'
abstract:
- lang: eng
text: The ability to adapt growth and development to temperature variations is crucial
to generate plant varieties resilient to predicted temperature changes. However,
the mechanisms underlying plant response to progressive increases in temperature
have just started to be elucidated. Here, we report that the Cyclin-dependent
Kinase G1 (CDKG1) is a central element in a thermo-sensitive mRNA splicing cascade
that transduces changes in ambient temperature into differential expression of
the fundamental spliceosome component, ATU2AF65A. CDKG1 is alternatively spliced
in a temperature-dependent manner. We found that this process is partly dependent
on both the Cyclin-dependent Kinase G2 (CDKG2) and the interacting co-factor CYCLIN
L1 resulting in two distinct messenger RNAs. Relative abundance of both CDKG1
transcripts correlates with ambient temperature and possibly with different expression
levels of the associated protein isoforms. Both CDKG1 alternative transcripts
are necessary to fully complement the expression of ATU2AF65A across the temperature
range. Our data support a previously unidentified temperature-dependent mechanism
based on the alternative splicing of CDKG1 and regulated by CDKG2 and CYCLIN L1.
We propose that changes in ambient temperature affect the relative abundance of
CDKG1 transcripts and this in turn translates into differential CDKG1 protein
expression coordinating the alternative splicing of ATU2AF65A. This article is
protected by copyright. All rights reserved.
acknowledgement: CN, DD and JHD were funded by the BBSRC (grant number BB/M009459/1).
NC was funded by the VIPS Program of the Austrian Federal Ministry of Science and
Research and the City of Vienna. AB and AF were supported by the Austrian Science
Fund (FWF) [DK W1207; SFB RNAreg F43-P10]
article_processing_charge: No
author:
- first_name: Nicola
full_name: Cavallari, Nicola
id: 457160E6-F248-11E8-B48F-1D18A9856A87
last_name: Cavallari
- first_name: Candida
full_name: Nibau, Candida
last_name: Nibau
- first_name: Armin
full_name: Fuchs, Armin
last_name: Fuchs
- first_name: Despoina
full_name: Dadarou, Despoina
last_name: Dadarou
- first_name: Andrea
full_name: Barta, Andrea
last_name: Barta
- first_name: John
full_name: Doonan, John
last_name: Doonan
citation:
ama: Cavallari N, Nibau C, Fuchs A, Dadarou D, Barta A, Doonan J. The cyclin‐dependent
kinase G group defines a thermo‐sensitive alternative splicing circuit modulating
the expression of Arabidopsis ATU 2AF 65A. The Plant Journal. 2018;94(6):1010-1022.
doi:10.1111/tpj.13914
apa: Cavallari, N., Nibau, C., Fuchs, A., Dadarou, D., Barta, A., & Doonan,
J. (2018). The cyclin‐dependent kinase G group defines a thermo‐sensitive alternative
splicing circuit modulating the expression of Arabidopsis ATU 2AF 65A. The
Plant Journal. Wiley. https://doi.org/10.1111/tpj.13914
chicago: Cavallari, Nicola, Candida Nibau, Armin Fuchs, Despoina Dadarou, Andrea
Barta, and John Doonan. “The Cyclin‐dependent Kinase G Group Defines a Thermo‐sensitive
Alternative Splicing Circuit Modulating the Expression of Arabidopsis ATU 2AF
65A.” The Plant Journal. Wiley, 2018. https://doi.org/10.1111/tpj.13914.
ieee: N. Cavallari, C. Nibau, A. Fuchs, D. Dadarou, A. Barta, and J. Doonan, “The
cyclin‐dependent kinase G group defines a thermo‐sensitive alternative splicing
circuit modulating the expression of Arabidopsis ATU 2AF 65A,” The Plant Journal,
vol. 94, no. 6. Wiley, pp. 1010–1022, 2018.
ista: Cavallari N, Nibau C, Fuchs A, Dadarou D, Barta A, Doonan J. 2018. The cyclin‐dependent
kinase G group defines a thermo‐sensitive alternative splicing circuit modulating
the expression of Arabidopsis ATU 2AF 65A. The Plant Journal. 94(6), 1010–1022.
mla: Cavallari, Nicola, et al. “The Cyclin‐dependent Kinase G Group Defines a Thermo‐sensitive
Alternative Splicing Circuit Modulating the Expression of Arabidopsis ATU 2AF
65A.” The Plant Journal, vol. 94, no. 6, Wiley, 2018, pp. 1010–22, doi:10.1111/tpj.13914.
short: N. Cavallari, C. Nibau, A. Fuchs, D. Dadarou, A. Barta, J. Doonan, The Plant
Journal 94 (2018) 1010–1022.
date_created: 2018-12-11T11:46:17Z
date_published: 2018-06-01T00:00:00Z
date_updated: 2023-09-19T10:07:08Z
day: '01'
ddc:
- '580'
department:
- _id: EvBe
doi: 10.1111/tpj.13914
external_id:
isi:
- '000434365500008'
file:
- access_level: open_access
checksum: d9d3ad3215ac0e581731443fca312266
content_type: application/pdf
creator: dernst
date_created: 2019-02-06T11:40:54Z
date_updated: 2020-07-14T12:46:22Z
file_id: '5934'
file_name: 2018_PlantJourn_Cavallari.pdf
file_size: 1543354
relation: main_file
file_date_updated: 2020-07-14T12:46:22Z
has_accepted_license: '1'
intvolume: ' 94'
isi: 1
issue: '6'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 1010 - 1022
publication: The Plant Journal
publication_status: published
publisher: Wiley
publist_id: '7426'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The cyclin‐dependent kinase G group defines a thermo‐sensitive alternative
splicing circuit modulating the expression of Arabidopsis ATU 2AF 65A
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 94
year: '2018'
...
---
_id: '156'
abstract:
- lang: eng
text: 'Imprecision in timing can sometimes be beneficial: Metric interval temporal
logic (MITL), disabling the expression of punctuality constraints, was shown to
translate to timed automata, yielding an elementary decision procedure. We show
how this principle extends to other forms of dense-time specification using regular
expressions. By providing a clean, automaton-based formal framework for non-punctual
languages, we are able to recover and extend several results in timed systems.
Metric interval regular expressions (MIRE) are introduced, providing regular expressions
with non-singular duration constraints. We obtain that MIRE are expressively complete
relative to a class of one-clock timed automata, which can be determinized using
additional clocks. Metric interval dynamic logic (MIDL) is then defined using
MIRE as temporal modalities. We show that MIDL generalizes known extensions of
MITL, while translating to timed automata at comparable cost.'
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Thomas
full_name: Ferrere, Thomas
id: 40960E6E-F248-11E8-B48F-1D18A9856A87
last_name: Ferrere
orcid: 0000-0001-5199-3143
citation:
ama: 'Ferrere T. The compound interest in relaxing punctuality. In: Vol 10951. Springer;
2018:147-164. doi:10.1007/978-3-319-95582-7_9'
apa: 'Ferrere, T. (2018). The compound interest in relaxing punctuality (Vol. 10951,
pp. 147–164). Presented at the FM: International Symposium on Formal Methods,
Oxford, UK: Springer. https://doi.org/10.1007/978-3-319-95582-7_9'
chicago: Ferrere, Thomas. “The Compound Interest in Relaxing Punctuality,” 10951:147–64.
Springer, 2018. https://doi.org/10.1007/978-3-319-95582-7_9.
ieee: 'T. Ferrere, “The compound interest in relaxing punctuality,” presented at
the FM: International Symposium on Formal Methods, Oxford, UK, 2018, vol. 10951,
pp. 147–164.'
ista: 'Ferrere T. 2018. The compound interest in relaxing punctuality. FM: International
Symposium on Formal Methods, LNCS, vol. 10951, 147–164.'
mla: Ferrere, Thomas. The Compound Interest in Relaxing Punctuality. Vol.
10951, Springer, 2018, pp. 147–64, doi:10.1007/978-3-319-95582-7_9.
short: T. Ferrere, in:, Springer, 2018, pp. 147–164.
conference:
end_date: 2018-07-17
location: Oxford, UK
name: 'FM: International Symposium on Formal Methods'
start_date: 2018-07-15
date_created: 2018-12-11T11:44:55Z
date_published: 2018-07-12T00:00:00Z
date_updated: 2023-09-19T10:05:37Z
day: '12'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.1007/978-3-319-95582-7_9
external_id:
isi:
- '000489765800009'
file:
- access_level: open_access
checksum: a045c213c42c445f1889326f8db82a0a
content_type: application/pdf
creator: dernst
date_created: 2020-10-09T06:22:41Z
date_updated: 2020-10-09T06:22:41Z
file_id: '8637'
file_name: 2018_LNCS_Ferrere.pdf
file_size: 485576
relation: main_file
success: 1
file_date_updated: 2020-10-09T06:22:41Z
has_accepted_license: '1'
intvolume: ' 10951'
isi: 1
language:
- iso: eng
month: '07'
oa: 1
oa_version: Submitted Version
page: 147 - 164
project:
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
publication_status: published
publisher: Springer
publist_id: '7765'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The compound interest in relaxing punctuality
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 10951
year: '2018'
...
---
_id: '104'
abstract:
- lang: eng
text: The biotrophic pathogen Ustilago maydis, the causative agent of corn smut
disease, infects one of the most important crops worldwide – Zea mays. To successfully
colonize its host, U. maydis secretes proteins, known as effectors, that suppress
plant defense responses and facilitate the establishment of biotrophy. In this
work, we describe the U. maydis effector protein Cce1. Cce1 is essential for virulence
and is upregulated during infection. Through microscopic analysis and in vitro
assays, we show that Cce1 is secreted from hyphae during filamentous growth of
the fungus. Strikingly, Δcce1 mutants are blocked at early stages of infection
and induce callose deposition as a plant defense response. Cce1 is highly conserved
among smut fungi and the Ustilago bromivora ortholog complemented the virulence
defect of the SG200Δcce1 deletion strain. These data indicate that Cce1 is a core
effector with apoplastic localization that is essential for U. maydis to infect
its host.
acknowledgement: 'the Austrian Science Fund (FWF): [P27429‐B22, P27818‐B22, I 3033‐B22],
and the Austrian Academy of Science (OEAW).'
article_processing_charge: No
author:
- first_name: Denise
full_name: Seitner, Denise
last_name: Seitner
- first_name: Simon
full_name: Uhse, Simon
last_name: Uhse
- first_name: Michelle C
full_name: Gallei, Michelle C
id: 35A03822-F248-11E8-B48F-1D18A9856A87
last_name: Gallei
orcid: 0000-0003-1286-7368
- first_name: Armin
full_name: Djamei, Armin
last_name: Djamei
citation:
ama: Seitner D, Uhse S, Gallei MC, Djamei A. The core effector Cce1 is required
for early infection of maize by Ustilago maydis. Molecular Plant Pathology.
2018;19(10):2277-2287. doi:10.1111/mpp.12698
apa: Seitner, D., Uhse, S., Gallei, M. C., & Djamei, A. (2018). The core effector
Cce1 is required for early infection of maize by Ustilago maydis. Molecular
Plant Pathology. Wiley. https://doi.org/10.1111/mpp.12698
chicago: Seitner, Denise, Simon Uhse, Michelle C Gallei, and Armin Djamei. “The
Core Effector Cce1 Is Required for Early Infection of Maize by Ustilago Maydis.”
Molecular Plant Pathology. Wiley, 2018. https://doi.org/10.1111/mpp.12698.
ieee: D. Seitner, S. Uhse, M. C. Gallei, and A. Djamei, “The core effector Cce1
is required for early infection of maize by Ustilago maydis,” Molecular Plant
Pathology, vol. 19, no. 10. Wiley, pp. 2277–2287, 2018.
ista: Seitner D, Uhse S, Gallei MC, Djamei A. 2018. The core effector Cce1 is required
for early infection of maize by Ustilago maydis. Molecular Plant Pathology. 19(10),
2277–2287.
mla: Seitner, Denise, et al. “The Core Effector Cce1 Is Required for Early Infection
of Maize by Ustilago Maydis.” Molecular Plant Pathology, vol. 19, no. 10,
Wiley, 2018, pp. 2277–87, doi:10.1111/mpp.12698.
short: D. Seitner, S. Uhse, M.C. Gallei, A. Djamei, Molecular Plant Pathology 19
(2018) 2277–2287.
date_created: 2018-12-11T11:44:39Z
date_published: 2018-10-01T00:00:00Z
date_updated: 2023-09-19T10:06:42Z
day: '01'
ddc:
- '580'
department:
- _id: GradSch
doi: 10.1111/mpp.12698
external_id:
isi:
- '000445624100006'
file:
- access_level: open_access
content_type: application/pdf
creator: dernst
date_created: 2018-12-18T09:46:00Z
date_updated: 2018-12-18T09:46:00Z
file_id: '5740'
file_name: 2018_MolecPlantPath_Seitner.pdf
file_size: 682335
relation: main_file
success: 1
file_date_updated: 2018-12-18T09:46:00Z
has_accepted_license: '1'
intvolume: ' 19'
isi: 1
issue: '10'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: 2277 - 2287
publication: Molecular Plant Pathology
publication_status: published
publisher: Wiley
publist_id: '7950'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The core effector Cce1 is required for early infection of maize by Ustilago
maydis
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 19
year: '2018'
...
---
_id: '40'
abstract:
- lang: eng
text: Hanemaaijer et al. (Molecular Ecology, 27, 2018) describe the genetic consequences
of the introgression of an insecticide resistance allele into a mosquito population.
Linked alleles initially increased, but many of these later declined. It is hard
to determine whether this decline was due to counter‐selection, rather than simply
to chance.
article_processing_charge: Yes (via OA deal)
article_type: letter_note
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Barton NH. The consequences of an introgression event. Molecular Ecology.
2018;27(24):4973-4975. doi:10.1111/mec.14950
apa: Barton, N. H. (2018). The consequences of an introgression event. Molecular
Ecology. Wiley. https://doi.org/10.1111/mec.14950
chicago: Barton, Nicholas H. “The Consequences of an Introgression Event.” Molecular
Ecology. Wiley, 2018. https://doi.org/10.1111/mec.14950.
ieee: N. H. Barton, “The consequences of an introgression event,” Molecular Ecology,
vol. 27, no. 24. Wiley, pp. 4973–4975, 2018.
ista: Barton NH. 2018. The consequences of an introgression event. Molecular Ecology.
27(24), 4973–4975.
mla: Barton, Nicholas H. “The Consequences of an Introgression Event.” Molecular
Ecology, vol. 27, no. 24, Wiley, 2018, pp. 4973–75, doi:10.1111/mec.14950.
short: N.H. Barton, Molecular Ecology 27 (2018) 4973–4975.
date_created: 2018-12-11T11:44:18Z
date_published: 2018-12-31T00:00:00Z
date_updated: 2023-09-19T10:06:08Z
day: '31'
ddc:
- '576'
department:
- _id: NiBa
doi: 10.1111/mec.14950
external_id:
isi:
- '000454600500001'
pmid:
- '30599087'
file:
- access_level: open_access
content_type: application/pdf
creator: apreinsp
date_created: 2019-07-19T06:54:46Z
date_updated: 2020-07-14T12:46:22Z
file_id: '6652'
file_name: 2018_MolecularEcology_BartonNick.pdf
file_size: 295452
relation: main_file
file_date_updated: 2020-07-14T12:46:22Z
has_accepted_license: '1'
intvolume: ' 27'
isi: 1
issue: '24'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 4973-4975
pmid: 1
publication: Molecular Ecology
publication_identifier:
issn:
- 1365294X
publication_status: published
publisher: Wiley
publist_id: '8014'
quality_controlled: '1'
related_material:
record:
- id: '9805'
relation: research_data
status: public
scopus_import: '1'
status: public
title: The consequences of an introgression event
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 27
year: '2018'
...
---
_id: '5861'
abstract:
- lang: eng
text: In zebrafish larvae, it is the cell type that determines how the cell responds
to a chemokine signal.
article_number: e37888
article_processing_charge: No
article_type: original
author:
- first_name: Jonna H
full_name: Alanko, Jonna H
id: 2CC12E8C-F248-11E8-B48F-1D18A9856A87
last_name: Alanko
orcid: 0000-0002-7698-3061
- first_name: Michael K
full_name: Sixt, Michael K
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
citation:
ama: Alanko JH, Sixt MK. The cell sets the tone. eLife. 2018;7. doi:10.7554/eLife.37888
apa: Alanko, J. H., & Sixt, M. K. (2018). The cell sets the tone. ELife.
eLife Sciences Publications. https://doi.org/10.7554/eLife.37888
chicago: Alanko, Jonna H, and Michael K Sixt. “The Cell Sets the Tone.” ELife.
eLife Sciences Publications, 2018. https://doi.org/10.7554/eLife.37888.
ieee: J. H. Alanko and M. K. Sixt, “The cell sets the tone,” eLife, vol.
7. eLife Sciences Publications, 2018.
ista: Alanko JH, Sixt MK. 2018. The cell sets the tone. eLife. 7, e37888.
mla: Alanko, Jonna H., and Michael K. Sixt. “The Cell Sets the Tone.” ELife,
vol. 7, e37888, eLife Sciences Publications, 2018, doi:10.7554/eLife.37888.
short: J.H. Alanko, M.K. Sixt, ELife 7 (2018).
date_created: 2019-01-20T22:59:19Z
date_published: 2018-06-06T00:00:00Z
date_updated: 2023-09-19T10:01:39Z
day: '06'
ddc:
- '570'
department:
- _id: MiSi
doi: 10.7554/eLife.37888
external_id:
isi:
- '000434375000001'
file:
- access_level: open_access
checksum: f1c7ec2a809408d763c4b529a98f9a3b
content_type: application/pdf
creator: dernst
date_created: 2019-02-13T10:52:11Z
date_updated: 2020-07-14T12:47:13Z
file_id: '5973'
file_name: 2018_eLife_Alanko.pdf
file_size: 358141
relation: main_file
file_date_updated: 2020-07-14T12:47:13Z
has_accepted_license: '1'
intvolume: ' 7'
isi: 1
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
publication: eLife
publication_identifier:
issn:
- 2050084X
publication_status: published
publisher: eLife Sciences Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: The cell sets the tone
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 7
year: '2018'
...
---
_id: '147'
abstract:
- lang: eng
text: The trafficking of subcellular cargos in eukaryotic cells crucially depends
on vesicle budding, a process mediated by ARF-GEFs (ADP-ribosylation factor guanine
nucleotide exchange factors). In plants, ARF-GEFs play essential roles in endocytosis,
vacuolar trafficking, recycling, secretion, and polar trafficking. Moreover, they
are important for plant development, mainly through controlling the polar subcellular
localization of PIN-FORMED (PIN) transporters of the plant hormone auxin. Here,
using a chemical genetics screen in Arabidopsis thaliana, we identified Endosidin
4 (ES4), an inhibitor of eukaryotic ARF-GEFs. ES4 acts similarly to and synergistically
with the established ARF-GEF inhibitor Brefeldin A and has broad effects on intracellular
trafficking, including endocytosis, exocytosis, and vacuolar targeting. Additionally,
Arabidopsis and yeast (Sacharomyces cerevisiae) mutants defective in ARF-GEF show
altered sensitivity to ES4. ES4 interferes with the activation-based membrane
association of the ARF1 GTPases, but not of their mutant variants that are activated
independently of ARF-GEF activity. Biochemical approaches and docking simulations
confirmed that ES4 specifically targets the SEC7 domain-containing ARF-GEFs. These
observations collectively identify ES4 as a chemical tool enabling the study of
ARF-GEF-mediated processes, including ARF-GEF-mediated plant development.
acknowledgement: We thank Gerd Jürgens, Sandra Richter, and Sheng Yang He for providing
antibodies; Maciek Adamowski, Fernando Aniento, Sebastian Bednarek, Nico Callewaert,
Matyás Fendrych, Elena Feraru, and Mugurel I. Feraru for helpful suggestions; Siamsa
Doyle for critical reading of the manuscript and helpful comments and suggestions;
and Stephanie Smith and Martine De Cock for help in editing and language corrections.
We acknowledge the core facility Cellular Imaging of CEITEC supported by the Czech-BioImaging
large RI project (LM2015062 funded by MEYS CR) for their support with obtaining
scientific data presented in this article. Plant Sciences Core Facility of CEITEC
Masaryk University is gratefully acknowledged for obtaining part of the scientific
data presented in this article. We acknowledge support from the Fondation pour la
Recherche Médicale and from the Institut National du Cancer (J.C.). The research
leading to these results was funded by the European Research Council under the European
Union's 7th Framework Program (FP7/2007-2013)/ERC grant agreement numbers 282300
and 742985 and the Czech Science Foundation GAČR (GA18-26981S; J.F.); Ministry of
Education, Youth, and Sports/MEYS of the Czech Republic under the Project CEITEC
2020 (LQ1601; T.N.); the China Science Council for a predoctoral fellowship (Q.L.);
a joint research project within the framework of cooperation between the Research
Foundation-Flanders and the Bulgarian Academy of Sciences (VS.025.13N; K.M. and
E.R.); Vetenskapsrådet and Vinnova (Verket för Innovationssystem; S.R.), Knut och
Alice Wallenbergs Stiftelse via “Shapesystem” Grant 2012.0050 (S.R.), Kempe stiftelserna
(P.G.), Tryggers CTS410 (P.G.).
article_processing_charge: No
article_type: original
author:
- first_name: Urszula
full_name: Kania, Urszula
id: 4AE5C486-F248-11E8-B48F-1D18A9856A87
last_name: Kania
- first_name: Tomasz
full_name: Nodzyński, Tomasz
last_name: Nodzyński
- first_name: Qing
full_name: Lu, Qing
last_name: Lu
- first_name: Glenn R
full_name: Hicks, Glenn R
last_name: Hicks
- first_name: Wim
full_name: Nerinckx, Wim
last_name: Nerinckx
- first_name: Kiril
full_name: Mishev, Kiril
last_name: Mishev
- first_name: Francois
full_name: Peurois, Francois
last_name: Peurois
- first_name: Jacqueline
full_name: Cherfils, Jacqueline
last_name: Cherfils
- first_name: Rycke Riet Maria
full_name: De, Rycke Riet Maria
last_name: De
- first_name: Peter
full_name: Grones, Peter
id: 399876EC-F248-11E8-B48F-1D18A9856A87
last_name: Grones
- first_name: Stéphanie
full_name: Robert, Stéphanie
last_name: Robert
- first_name: Eugenia
full_name: Russinova, Eugenia
last_name: Russinova
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Kania U, Nodzyński T, Lu Q, et al. The inhibitor Endosidin 4 targets SEC7 domain-type
ARF GTPase exchange factors and interferes with sub cellular trafficking in eukaryotes.
The Plant Cell. 2018;30(10):2553-2572. doi:10.1105/tpc.18.00127
apa: Kania, U., Nodzyński, T., Lu, Q., Hicks, G. R., Nerinckx, W., Mishev, K., …
Friml, J. (2018). The inhibitor Endosidin 4 targets SEC7 domain-type ARF GTPase
exchange factors and interferes with sub cellular trafficking in eukaryotes. The
Plant Cell. Oxford University Press. https://doi.org/10.1105/tpc.18.00127
chicago: Kania, Urszula, Tomasz Nodzyński, Qing Lu, Glenn R Hicks, Wim Nerinckx,
Kiril Mishev, Francois Peurois, et al. “The Inhibitor Endosidin 4 Targets SEC7
Domain-Type ARF GTPase Exchange Factors and Interferes with Sub Cellular Trafficking
in Eukaryotes.” The Plant Cell. Oxford University Press, 2018. https://doi.org/10.1105/tpc.18.00127.
ieee: U. Kania et al., “The inhibitor Endosidin 4 targets SEC7 domain-type
ARF GTPase exchange factors and interferes with sub cellular trafficking in eukaryotes,”
The Plant Cell, vol. 30, no. 10. Oxford University Press, pp. 2553–2572,
2018.
ista: Kania U, Nodzyński T, Lu Q, Hicks GR, Nerinckx W, Mishev K, Peurois F, Cherfils
J, De RRM, Grones P, Robert S, Russinova E, Friml J. 2018. The inhibitor Endosidin
4 targets SEC7 domain-type ARF GTPase exchange factors and interferes with sub
cellular trafficking in eukaryotes. The Plant Cell. 30(10), 2553–2572.
mla: Kania, Urszula, et al. “The Inhibitor Endosidin 4 Targets SEC7 Domain-Type
ARF GTPase Exchange Factors and Interferes with Sub Cellular Trafficking in Eukaryotes.”
The Plant Cell, vol. 30, no. 10, Oxford University Press, 2018, pp. 2553–72,
doi:10.1105/tpc.18.00127.
short: U. Kania, T. Nodzyński, Q. Lu, G.R. Hicks, W. Nerinckx, K. Mishev, F. Peurois,
J. Cherfils, R.R.M. De, P. Grones, S. Robert, E. Russinova, J. Friml, The Plant
Cell 30 (2018) 2553–2572.
date_created: 2018-12-11T11:44:52Z
date_published: 2018-11-12T00:00:00Z
date_updated: 2023-09-19T10:09:12Z
day: '12'
department:
- _id: JiFr
doi: 10.1105/tpc.18.00127
ec_funded: 1
external_id:
isi:
- '000450000500023'
pmid:
- '30018156'
intvolume: ' 30'
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issue: '10'
language:
- iso: eng
main_file_link:
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url: https://doi.org/10.1105/tpc.18.00127
month: '11'
oa: 1
oa_version: Published Version
page: 2553 - 2572
pmid: 1
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '282300'
name: Polarity and subcellular dynamics in plants
- _id: 261099A6-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742985'
name: Tracing Evolution of Auxin Transport and Polarity in Plants
publication: The Plant Cell
publication_identifier:
issn:
- 1040-4651
publication_status: published
publisher: Oxford University Press
publist_id: '7776'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The inhibitor Endosidin 4 targets SEC7 domain-type ARF GTPase exchange factors
and interferes with sub cellular trafficking in eukaryotes
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 30
year: '2018'
...
---
_id: '146'
abstract:
- lang: eng
text: The root cap protects the stem cell niche of angiosperm roots from damage.
In Arabidopsis, lateral root cap (LRC) cells covering the meristematic zone are
regularly lost through programmed cell death, while the outermost layer of the
root cap covering the tip is repeatedly sloughed. Efficient coordination with
stem cells producing new layers is needed to maintain a constant size of the cap.
We present a signalling pair, the peptide IDA-LIKE1 (IDL1) and its receptor HAESA-LIKE2
(HSL2), mediating such communication. Live imaging over several days characterized
this process from initial fractures in LRC cell files to full separation of a
layer. Enhanced expression of IDL1 in the separating root cap layers resulted
in increased frequency of sloughing, balanced with generation of new layers in
a HSL2-dependent manner. Transcriptome analyses linked IDL1-HSL2 signalling to
the transcription factors BEARSKIN1/2 and genes associated with programmed cell
death. Mutations in either IDL1 or HSL2 slowed down cell division, maturation
and separation. Thus, IDL1-HSL2 signalling potentiates dynamic regulation of the
homeostatic balance between stem cell division and sloughing activity.
article_processing_charge: No
article_type: original
author:
- first_name: Chun Lin
full_name: Shi, Chun Lin
last_name: Shi
- first_name: Daniel
full_name: Von Wangenheim, Daniel
id: 49E91952-F248-11E8-B48F-1D18A9856A87
last_name: Von Wangenheim
orcid: 0000-0002-6862-1247
- first_name: Ullrich
full_name: Herrmann, Ullrich
last_name: Herrmann
- first_name: Mari
full_name: Wildhagen, Mari
last_name: Wildhagen
- first_name: Ivan
full_name: Kulik, Ivan
id: F0AB3FCE-02D1-11E9-BD0E-99399A5D3DEB
last_name: Kulik
- first_name: Andreas
full_name: Kopf, Andreas
last_name: Kopf
- first_name: Takashi
full_name: Ishida, Takashi
last_name: Ishida
- first_name: Vilde
full_name: Olsson, Vilde
last_name: Olsson
- first_name: Mari Kristine
full_name: Anker, Mari Kristine
last_name: Anker
- first_name: Markus
full_name: Albert, Markus
last_name: Albert
- first_name: Melinka A
full_name: Butenko, Melinka A
last_name: Butenko
- first_name: Georg
full_name: Felix, Georg
last_name: Felix
- first_name: Shinichiro
full_name: Sawa, Shinichiro
last_name: Sawa
- first_name: Manfred
full_name: Claassen, Manfred
last_name: Claassen
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Reidunn B
full_name: Aalen, Reidunn B
last_name: Aalen
citation:
ama: Shi CL, von Wangenheim D, Herrmann U, et al. The dynamics of root cap sloughing
in Arabidopsis is regulated by peptide signalling. Nature Plants. 2018;4(8):596-604.
doi:10.1038/s41477-018-0212-z
apa: Shi, C. L., von Wangenheim, D., Herrmann, U., Wildhagen, M., Kulik, I., Kopf,
A., … Aalen, R. B. (2018). The dynamics of root cap sloughing in Arabidopsis is
regulated by peptide signalling. Nature Plants. Nature Publishing Group.
https://doi.org/10.1038/s41477-018-0212-z
chicago: Shi, Chun Lin, Daniel von Wangenheim, Ullrich Herrmann, Mari Wildhagen,
Ivan Kulik, Andreas Kopf, Takashi Ishida, et al. “The Dynamics of Root Cap Sloughing
in Arabidopsis Is Regulated by Peptide Signalling.” Nature Plants. Nature
Publishing Group, 2018. https://doi.org/10.1038/s41477-018-0212-z.
ieee: C. L. Shi et al., “The dynamics of root cap sloughing in Arabidopsis
is regulated by peptide signalling,” Nature Plants, vol. 4, no. 8. Nature
Publishing Group, pp. 596–604, 2018.
ista: Shi CL, von Wangenheim D, Herrmann U, Wildhagen M, Kulik I, Kopf A, Ishida
T, Olsson V, Anker MK, Albert M, Butenko MA, Felix G, Sawa S, Claassen M, Friml
J, Aalen RB. 2018. The dynamics of root cap sloughing in Arabidopsis is regulated
by peptide signalling. Nature Plants. 4(8), 596–604.
mla: Shi, Chun Lin, et al. “The Dynamics of Root Cap Sloughing in Arabidopsis Is
Regulated by Peptide Signalling.” Nature Plants, vol. 4, no. 8, Nature
Publishing Group, 2018, pp. 596–604, doi:10.1038/s41477-018-0212-z.
short: C.L. Shi, D. von Wangenheim, U. Herrmann, M. Wildhagen, I. Kulik, A. Kopf,
T. Ishida, V. Olsson, M.K. Anker, M. Albert, M.A. Butenko, G. Felix, S. Sawa,
M. Claassen, J. Friml, R.B. Aalen, Nature Plants 4 (2018) 596–604.
date_created: 2018-12-11T11:44:52Z
date_published: 2018-07-30T00:00:00Z
date_updated: 2023-09-19T10:08:45Z
day: '30'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1038/s41477-018-0212-z
external_id:
isi:
- '000443861300016'
pmid:
- '30061750'
file:
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creator: dernst
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oa: 1
oa_version: Submitted Version
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publisher: Nature Publishing Group
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related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/new-process-in-root-development-discovered/
scopus_import: '1'
status: public
title: The dynamics of root cap sloughing in Arabidopsis is regulated by peptide signalling
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 4
year: '2018'
...
---
_id: '293'
abstract:
- lang: eng
text: People sometimes make their admirable deeds and accomplishments hard to spot,
such as by giving anonymously or avoiding bragging. Such ‘buried’ signals are
hard to reconcile with standard models of signalling or indirect reciprocity,
which motivate costly pro-social behaviour by reputational gains. To explain these
phenomena, we design a simple game theory model, which we call the signal-burying
game. This game has the feature that senders can bury their signal by deliberately
reducing the probability of the signal being observed. If the signal is observed,
however, it is identified as having been buried. We show under which conditions
buried signals can be maintained, using static equilibrium concepts and calculations
of the evolutionary dynamics. We apply our analysis to shed light on a number
of otherwise puzzling social phenomena, including modesty, anonymous donations,
subtlety in art and fashion, and overeagerness.
acknowledgement: This work was supported by a grant from the John Templeton Foundation
and by the Office of Naval Research Grant N00014-16-1-2914 (M.A.N.). C.H. acknowledges
generous support from the ISTFELLOW programme and by the Schrödinger scholarship
of the Austrian Science Fund (FWF) J3475.
article_processing_charge: No
article_type: original
author:
- first_name: Moshe
full_name: Hoffman, Moshe
last_name: Hoffman
- first_name: Christian
full_name: Hilbe, Christian
id: 2FDF8F3C-F248-11E8-B48F-1D18A9856A87
last_name: Hilbe
orcid: 0000-0001-5116-955X
- first_name: Martin
full_name: Nowak, Martin
last_name: Nowak
citation:
ama: Hoffman M, Hilbe C, Nowak M. The signal-burying game can explain why we obscure
positive traits and good deeds. Nature Human Behaviour. 2018;2:397-404.
doi:10.1038/s41562-018-0354-z
apa: Hoffman, M., Hilbe, C., & Nowak, M. (2018). The signal-burying game can
explain why we obscure positive traits and good deeds. Nature Human Behaviour.
Nature Publishing Group. https://doi.org/10.1038/s41562-018-0354-z
chicago: Hoffman, Moshe, Christian Hilbe, and Martin Nowak. “The Signal-Burying
Game Can Explain Why We Obscure Positive Traits and Good Deeds.” Nature Human
Behaviour. Nature Publishing Group, 2018. https://doi.org/10.1038/s41562-018-0354-z.
ieee: M. Hoffman, C. Hilbe, and M. Nowak, “The signal-burying game can explain why
we obscure positive traits and good deeds,” Nature Human Behaviour, vol.
2. Nature Publishing Group, pp. 397–404, 2018.
ista: Hoffman M, Hilbe C, Nowak M. 2018. The signal-burying game can explain why
we obscure positive traits and good deeds. Nature Human Behaviour. 2, 397–404.
mla: Hoffman, Moshe, et al. “The Signal-Burying Game Can Explain Why We Obscure
Positive Traits and Good Deeds.” Nature Human Behaviour, vol. 2, Nature
Publishing Group, 2018, pp. 397–404, doi:10.1038/s41562-018-0354-z.
short: M. Hoffman, C. Hilbe, M. Nowak, Nature Human Behaviour 2 (2018) 397–404.
date_created: 2018-12-11T11:45:39Z
date_published: 2018-05-28T00:00:00Z
date_updated: 2023-09-19T10:12:03Z
day: '28'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1038/s41562-018-0354-z
ec_funded: 1
external_id:
isi:
- '000435551300009'
file:
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checksum: 32efaf06a597495c184df91b3fbb19c0
content_type: application/pdf
creator: dernst
date_created: 2019-11-19T08:17:23Z
date_updated: 2020-07-14T12:45:54Z
file_id: '7051'
file_name: 2018_NatureHumanBeh_Hoffman.pdf
file_size: 194734
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file_date_updated: 2020-07-14T12:45:54Z
has_accepted_license: '1'
intvolume: ' 2'
isi: 1
language:
- iso: eng
month: '05'
oa: 1
oa_version: Submitted Version
page: 397 - 404
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Nature Human Behaviour
publication_status: published
publisher: Nature Publishing Group
publist_id: '7588'
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/the-logic-of-modesty-why-it-pays-to-be-humble/
scopus_import: '1'
status: public
title: The signal-burying game can explain why we obscure positive traits and good
deeds
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 2
year: '2018'
...
---
_id: '455'
abstract:
- lang: eng
text: The derivation of effective evolution equations is central to the study of
non-stationary quantum many-body systems, and widely used in contexts such as
superconductivity, nuclear physics, Bose–Einstein condensation and quantum chemistry.
We reformulate the Dirac–Frenkel approximation principle in terms of reduced density
matrices and apply it to fermionic and bosonic many-body systems. We obtain the
Bogoliubov–de Gennes and Hartree–Fock–Bogoliubov equations, respectively. While
we do not prove quantitative error estimates, our formulation does show that the
approximation is optimal within the class of quasifree states. Furthermore, we
prove well-posedness of the Bogoliubov–de Gennes equations in energy space and
discuss conserved quantities
acknowledgement: Open access funding provided by Institute of Science and Technology
(IST Austria). The authors acknowledge support by ERC Advanced Grant 321029 and
by VILLUM FONDEN via the QMATH Centre of Excellence (Grant No. 10059). The authors
would like to thank Sébastien Breteaux, Enno Lenzmann, Mathieu Lewin and Jochen
Schmid for comments and discussions about well-posedness of the Bogoliubov–de Gennes
equations.
alternative_title:
- Annales Henri Poincare
article_processing_charge: No
author:
- first_name: Niels P
full_name: Benedikter, Niels P
id: 3DE6C32A-F248-11E8-B48F-1D18A9856A87
last_name: Benedikter
orcid: 0000-0002-1071-6091
- first_name: Jérémy
full_name: Sok, Jérémy
last_name: Sok
- first_name: Jan
full_name: Solovej, Jan
last_name: Solovej
citation:
ama: Benedikter NP, Sok J, Solovej J. The Dirac–Frenkel principle for reduced density
matrices and the Bogoliubov–de Gennes equations. Annales Henri Poincare.
2018;19(4):1167-1214. doi:10.1007/s00023-018-0644-z
apa: Benedikter, N. P., Sok, J., & Solovej, J. (2018). The Dirac–Frenkel principle
for reduced density matrices and the Bogoliubov–de Gennes equations. Annales
Henri Poincare. Birkhäuser. https://doi.org/10.1007/s00023-018-0644-z
chicago: Benedikter, Niels P, Jérémy Sok, and Jan Solovej. “The Dirac–Frenkel Principle
for Reduced Density Matrices and the Bogoliubov–de Gennes Equations.” Annales
Henri Poincare. Birkhäuser, 2018. https://doi.org/10.1007/s00023-018-0644-z.
ieee: N. P. Benedikter, J. Sok, and J. Solovej, “The Dirac–Frenkel principle for
reduced density matrices and the Bogoliubov–de Gennes equations,” Annales Henri
Poincare, vol. 19, no. 4. Birkhäuser, pp. 1167–1214, 2018.
ista: Benedikter NP, Sok J, Solovej J. 2018. The Dirac–Frenkel principle for reduced
density matrices and the Bogoliubov–de Gennes equations. Annales Henri Poincare.
19(4), 1167–1214.
mla: Benedikter, Niels P., et al. “The Dirac–Frenkel Principle for Reduced Density
Matrices and the Bogoliubov–de Gennes Equations.” Annales Henri Poincare,
vol. 19, no. 4, Birkhäuser, 2018, pp. 1167–214, doi:10.1007/s00023-018-0644-z.
short: N.P. Benedikter, J. Sok, J. Solovej, Annales Henri Poincare 19 (2018) 1167–1214.
date_created: 2018-12-11T11:46:34Z
date_published: 2018-04-01T00:00:00Z
date_updated: 2023-09-19T10:07:41Z
day: '01'
ddc:
- '510'
- '539'
department:
- _id: RoSe
doi: 10.1007/s00023-018-0644-z
external_id:
isi:
- '000427578900006'
file:
- access_level: open_access
checksum: 883eeccba8384ad7fcaa28761d99a0fa
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:11:57Z
date_updated: 2020-07-14T12:46:31Z
file_id: '4914'
file_name: IST-2018-993-v1+1_2018_Benedikter_Dirac.pdf
file_size: 923252
relation: main_file
file_date_updated: 2020-07-14T12:46:31Z
has_accepted_license: '1'
intvolume: ' 19'
isi: 1
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 1167 - 1214
publication: Annales Henri Poincare
publication_status: published
publisher: Birkhäuser
publist_id: '7367'
pubrep_id: '993'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The Dirac–Frenkel principle for reduced density matrices and the Bogoliubov–de
Gennes equations
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 19
year: '2018'
...
---
_id: '314'
abstract:
- lang: eng
text: The interface of physics and biology pro-vides a fruitful environment for
generatingnew concepts and exciting ways forwardto understanding living matter.
Examplesof successful studies include the estab-lishment and readout of morphogen
gra-dients during development, signal pro-cessing in protein and genetic networks,the
role of fluctuations in determining thefates of cells and tissues, and collectiveeffects
in proteins and in tissues. It is nothard to envision that significant further
ad-vances will translate to societal benefitsby initiating the development of new
de-vices and strategies for curing disease.However, research at the interface
posesvarious challenges, in particular for youngscientists, and current institutions
arerarely designed to facilitate such scientificprograms. In this Letter, we propose
aninternational initiative that addressesthese challenges through the establish-ment
of a worldwide network of platformsfor cross-disciplinary training and incuba-tors
for starting new collaborations.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Guntram
full_name: Bauer, Guntram
last_name: Bauer
- first_name: Nikta
full_name: Fakhri, Nikta
last_name: Fakhri
- first_name: Anna
full_name: Kicheva, Anna
id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
last_name: Kicheva
orcid: 0000-0003-4509-4998
- first_name: Jané
full_name: Kondev, Jané
last_name: Kondev
- first_name: Karsten
full_name: Kruse, Karsten
last_name: Kruse
- first_name: Hiroyuki
full_name: Noji, Hiroyuki
last_name: Noji
- first_name: Daniel
full_name: Riveline, Daniel
last_name: Riveline
- first_name: Timothy
full_name: Saunders, Timothy
last_name: Saunders
- first_name: Mukund
full_name: Thatta, Mukund
last_name: Thatta
- first_name: Eric
full_name: Wieschaus, Eric
last_name: Wieschaus
citation:
ama: Bauer G, Fakhri N, Kicheva A, et al. The science of living matter for tomorrow.
Cell Systems. 2018;6(4):400-402. doi:10.1016/j.cels.2018.04.003
apa: Bauer, G., Fakhri, N., Kicheva, A., Kondev, J., Kruse, K., Noji, H., … Wieschaus,
E. (2018). The science of living matter for tomorrow. Cell Systems. Cell
Press. https://doi.org/10.1016/j.cels.2018.04.003
chicago: Bauer, Guntram, Nikta Fakhri, Anna Kicheva, Jané Kondev, Karsten Kruse,
Hiroyuki Noji, Daniel Riveline, Timothy Saunders, Mukund Thatta, and Eric Wieschaus.
“The Science of Living Matter for Tomorrow.” Cell Systems. Cell Press,
2018. https://doi.org/10.1016/j.cels.2018.04.003.
ieee: G. Bauer et al., “The science of living matter for tomorrow,” Cell
Systems, vol. 6, no. 4. Cell Press, pp. 400–402, 2018.
ista: Bauer G, Fakhri N, Kicheva A, Kondev J, Kruse K, Noji H, Riveline D, Saunders
T, Thatta M, Wieschaus E. 2018. The science of living matter for tomorrow. Cell
Systems. 6(4), 400–402.
mla: Bauer, Guntram, et al. “The Science of Living Matter for Tomorrow.” Cell
Systems, vol. 6, no. 4, Cell Press, 2018, pp. 400–02, doi:10.1016/j.cels.2018.04.003.
short: G. Bauer, N. Fakhri, A. Kicheva, J. Kondev, K. Kruse, H. Noji, D. Riveline,
T. Saunders, M. Thatta, E. Wieschaus, Cell Systems 6 (2018) 400–402.
date_created: 2018-12-11T11:45:46Z
date_published: 2018-04-25T00:00:00Z
date_updated: 2023-09-19T10:11:25Z
day: '25'
department:
- _id: AnKi
doi: 10.1016/j.cels.2018.04.003
external_id:
isi:
- '000432192100003'
pmid:
- '29698645'
intvolume: ' 6'
isi: 1
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.cels.2018.04.003
month: '04'
oa: 1
oa_version: Published Version
page: 400 - 402
pmid: 1
publication: Cell Systems
publication_identifier:
eissn:
- 2405-4712
publication_status: published
publisher: Cell Press
publist_id: '7551'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The science of living matter for tomorrow
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 6
year: '2018'
...
---
_id: '565'
abstract:
- lang: eng
text: 'We re-examine the model of Kirkpatrick and Barton for the spread of an inversion
into a local population. This model assumes that local selection maintains alleles
at two or more loci, despite immigration of alternative alleles at these loci
from another population. We show that an inversion is favored because it prevents
the breakdown of linkage disequilibrium generated by migration; the selective
advantage of an inversion is proportional to the amount of recombination between
the loci involved, as in other cases where inversions are selected for. We derive
expressions for the rate of spread of an inversion; when the loci covered by the
inversion are tightly linked, these conditions deviate substantially from those
proposed previously, and imply that an inversion can then have only a small advantage. '
article_processing_charge: No
article_type: original
author:
- first_name: Brian
full_name: Charlesworth, Brian
last_name: Charlesworth
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Charlesworth B, Barton NH. The spread of an inversion with migration and selection.
Genetics. 2018;208(1):377-382. doi:10.1534/genetics.117.300426
apa: Charlesworth, B., & Barton, N. H. (2018). The spread of an inversion with
migration and selection. Genetics. Genetics . https://doi.org/10.1534/genetics.117.300426
chicago: Charlesworth, Brian, and Nicholas H Barton. “The Spread of an Inversion
with Migration and Selection.” Genetics. Genetics , 2018. https://doi.org/10.1534/genetics.117.300426.
ieee: B. Charlesworth and N. H. Barton, “The spread of an inversion with migration
and selection,” Genetics, vol. 208, no. 1. Genetics , pp. 377–382, 2018.
ista: Charlesworth B, Barton NH. 2018. The spread of an inversion with migration
and selection. Genetics. 208(1), 377–382.
mla: Charlesworth, Brian, and Nicholas H. Barton. “The Spread of an Inversion with
Migration and Selection.” Genetics, vol. 208, no. 1, Genetics , 2018, pp.
377–82, doi:10.1534/genetics.117.300426.
short: B. Charlesworth, N.H. Barton, Genetics 208 (2018) 377–382.
date_created: 2018-12-11T11:47:12Z
date_published: 2018-01-01T00:00:00Z
date_updated: 2023-09-19T10:12:31Z
day: '01'
department:
- _id: NiBa
doi: 10.1534/genetics.117.300426
external_id:
isi:
- '000419356300025'
pmid:
- '29158424'
intvolume: ' 208'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753870/
month: '01'
oa: 1
oa_version: Published Version
page: 377 - 382
pmid: 1
publication: Genetics
publication_status: published
publisher: 'Genetics '
publist_id: '7249'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The spread of an inversion with migration and selection
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 208
year: '2018'
...
---
_id: '446'
abstract:
- lang: eng
text: We prove that in Thomas–Fermi–Dirac–von Weizsäcker theory, a nucleus of charge
Z > 0 can bind at most Z + C electrons, where C is a universal constant. This
result is obtained through a comparison with Thomas-Fermi theory which, as a by-product,
gives bounds on the screened nuclear potential and the radius of the minimizer.
A key ingredient of the proof is a novel technique to control the particles in
the exterior region, which also applies to the liquid drop model with a nuclear
background potential.
acknowledgement: "We thank the referee for helpful suggestions that improved the presentation
of the paper. We also acknowledge partial support by National Science Foundation
Grant DMS-1363432 (R.L.F.), Austrian Science Fund (FWF) Project Nr. P 27533-N27
(P.T.N.), CONICYT (Chile) through CONICYT–PCHA/ Doctorado Nacional/2014, and Iniciativa
Científica Milenio (Chile) through Millenium Nucleus RC–120002 “Física Matemática”
(H.V.D.B.).\r\n"
article_processing_charge: No
article_type: original
author:
- first_name: Rupert
full_name: Frank, Rupert
last_name: Frank
- first_name: Nam
full_name: Phan Thanh, Nam
id: 404092F4-F248-11E8-B48F-1D18A9856A87
last_name: Phan Thanh
- first_name: Hanne
full_name: Van Den Bosch, Hanne
last_name: Van Den Bosch
citation:
ama: Frank R, Nam P, Van Den Bosch H. The ionization conjecture in Thomas–Fermi–Dirac–von
Weizsäcker theory. Communications on Pure and Applied Mathematics. 2018;71(3):577-614.
doi:10.1002/cpa.21717
apa: Frank, R., Nam, P., & Van Den Bosch, H. (2018). The ionization conjecture
in Thomas–Fermi–Dirac–von Weizsäcker theory. Communications on Pure and Applied
Mathematics. Wiley-Blackwell. https://doi.org/10.1002/cpa.21717
chicago: Frank, Rupert, Phan Nam, and Hanne Van Den Bosch. “The Ionization Conjecture
in Thomas–Fermi–Dirac–von Weizsäcker Theory.” Communications on Pure and Applied
Mathematics. Wiley-Blackwell, 2018. https://doi.org/10.1002/cpa.21717.
ieee: R. Frank, P. Nam, and H. Van Den Bosch, “The ionization conjecture in Thomas–Fermi–Dirac–von
Weizsäcker theory,” Communications on Pure and Applied Mathematics, vol.
71, no. 3. Wiley-Blackwell, pp. 577–614, 2018.
ista: Frank R, Nam P, Van Den Bosch H. 2018. The ionization conjecture in Thomas–Fermi–Dirac–von
Weizsäcker theory. Communications on Pure and Applied Mathematics. 71(3), 577–614.
mla: Frank, Rupert, et al. “The Ionization Conjecture in Thomas–Fermi–Dirac–von
Weizsäcker Theory.” Communications on Pure and Applied Mathematics, vol.
71, no. 3, Wiley-Blackwell, 2018, pp. 577–614, doi:10.1002/cpa.21717.
short: R. Frank, P. Nam, H. Van Den Bosch, Communications on Pure and Applied Mathematics
71 (2018) 577–614.
date_created: 2018-12-11T11:46:31Z
date_published: 2018-03-01T00:00:00Z
date_updated: 2023-09-19T10:09:40Z
day: '01'
department:
- _id: RoSe
doi: 10.1002/cpa.21717
external_id:
arxiv:
- '1606.07355'
isi:
- '000422675800004'
intvolume: ' 71'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1606.07355
month: '03'
oa: 1
oa_version: Preprint
page: 577 - 614
publication: Communications on Pure and Applied Mathematics
publication_status: published
publisher: Wiley-Blackwell
publist_id: '7377'
quality_controlled: '1'
status: public
title: The ionization conjecture in Thomas–Fermi–Dirac–von Weizsäcker theory
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 71
year: '2018'
...
---
_id: '430'
abstract:
- lang: eng
text: In this issue of GENETICS, a new method for detecting natural selection on
polygenic traits is developed and applied to sev- eral human examples ( Racimo
et al. 2018 ). By de fi nition, many loci contribute to variation in polygenic
traits, and a challenge for evolutionary ge neticists has been that these traits
can evolve by small, nearly undetectable shifts in allele frequencies across each
of many, typically unknown, loci. Recently, a helpful remedy has arisen. Genome-wide
associ- ation studies (GWAS) have been illuminating sets of loci that can be interrogated
jointly for c hanges in allele frequencies. By aggregating small signal s of change
across many such loci, directional natural selection is now in principle detect-
able using genetic data, even for highly polygenic traits. This is an exciting
arena of progress – with these methods, tests can be made for selection associated
with traits, and we can now study selection in what may be its most prevalent
mode. The continuing fast pace of GWAS publications suggest there will be many
more polygenic tests of selection in the near future, as every new GWAS is an
opportunity for an accom- panying test of polygenic selection. However, it is
important to be aware of complications th at arise in interpretation, especially
given that these studies may easily be misinter- preted both in and outside the
evolutionary genetics commu- nity. Here, we provide context for understanding
polygenic tests and urge caution regarding how these results are inter- preted
and reported upon more broadly.
article_processing_charge: No
author:
- first_name: John
full_name: Novembre, John
last_name: Novembre
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Novembre J, Barton NH. Tread lightly interpreting polygenic tests of selection.
Genetics. 2018;208(4):1351-1355. doi:10.1534/genetics.118.300786
apa: Novembre, J., & Barton, N. H. (2018). Tread lightly interpreting polygenic
tests of selection. Genetics. Genetics Society of America. https://doi.org/10.1534/genetics.118.300786
chicago: Novembre, John, and Nicholas H Barton. “Tread Lightly Interpreting Polygenic
Tests of Selection.” Genetics. Genetics Society of America, 2018. https://doi.org/10.1534/genetics.118.300786.
ieee: J. Novembre and N. H. Barton, “Tread lightly interpreting polygenic tests
of selection,” Genetics, vol. 208, no. 4. Genetics Society of America,
pp. 1351–1355, 2018.
ista: Novembre J, Barton NH. 2018. Tread lightly interpreting polygenic tests of
selection. Genetics. 208(4), 1351–1355.
mla: Novembre, John, and Nicholas H. Barton. “Tread Lightly Interpreting Polygenic
Tests of Selection.” Genetics, vol. 208, no. 4, Genetics Society of America,
2018, pp. 1351–55, doi:10.1534/genetics.118.300786.
short: J. Novembre, N.H. Barton, Genetics 208 (2018) 1351–1355.
date_created: 2018-12-11T11:46:26Z
date_published: 2018-04-01T00:00:00Z
date_updated: 2023-09-19T10:17:30Z
day: '01'
ddc:
- '576'
department:
- _id: NiBa
doi: 10.1534/genetics.118.300786
external_id:
isi:
- '000429094400005'
file:
- access_level: open_access
checksum: 3d838dc285df394376555b794b6a5ad1
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:12:40Z
date_updated: 2020-07-14T12:46:26Z
file_id: '4958'
file_name: IST-2018-1012-v1+1_2018_Barton_Tread.pdf
file_size: 500129
relation: main_file
file_date_updated: 2020-07-14T12:46:26Z
has_accepted_license: '1'
intvolume: ' 208'
isi: 1
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 1351 - 1355
publication: Genetics
publication_status: published
publisher: Genetics Society of America
publist_id: '7393'
pubrep_id: '1012'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Tread lightly interpreting polygenic tests of selection
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 208
year: '2018'
...
---
_id: '199'
abstract:
- lang: eng
text: Sex-biased genes are central to the study of sexual selection, sexual antagonism,
and sex chromosome evolution. We describe a comprehensive de novo assembled transcriptome
in the common frog Rana temporaria based on five developmental stages and three
adult tissues from both sexes, obtained from a population with karyotypically
homomorphic but genetically differentiated sex chromosomes. This allows the study
of sex-biased gene expression throughout development, and its effect on the rate
of gene evolution while accounting for pleiotropic expression, which is known
to negatively correlate with the evolutionary rate. Overall, sex-biased genes
had little overlap among developmental stages and adult tissues. Late developmental
stages and gonad tissues had the highest numbers of stage-or tissue-specific genes.
We find that pleiotropic gene expression is a better predictor than sex bias for
the evolutionary rate of genes, though it often interacts with sex bias. Although
genetically differentiated, the sex chromosomes were not enriched in sex-biased
genes, possibly due to a very recent arrest of XY recombination. These results
extend our understanding of the developmental dynamics, tissue specificity, and
genomic localization of sex-biased genes.
article_number: '294'
article_processing_charge: No
author:
- first_name: Wen
full_name: Ma, Wen
last_name: Ma
- first_name: Paris
full_name: Veltsos, Paris
last_name: Veltsos
- first_name: Melissa A
full_name: Toups, Melissa A
id: 4E099E4E-F248-11E8-B48F-1D18A9856A87
last_name: Toups
orcid: 0000-0002-9752-7380
- first_name: Nicolas
full_name: Rodrigues, Nicolas
last_name: Rodrigues
- first_name: Roberto
full_name: Sermier, Roberto
last_name: Sermier
- first_name: Daniel
full_name: Jeffries, Daniel
last_name: Jeffries
- first_name: Nicolas
full_name: Perrin, Nicolas
last_name: Perrin
citation:
ama: Ma W, Veltsos P, Toups MA, et al. Tissue specificity and dynamics of sex biased
gene expression in a common frog population with differentiated, yet homomorphic,
sex chromosomes. Genes. 2018;9(6). doi:10.3390/genes9060294
apa: Ma, W., Veltsos, P., Toups, M. A., Rodrigues, N., Sermier, R., Jeffries, D.,
& Perrin, N. (2018). Tissue specificity and dynamics of sex biased gene expression
in a common frog population with differentiated, yet homomorphic, sex chromosomes.
Genes. MDPI AG. https://doi.org/10.3390/genes9060294
chicago: Ma, Wen, Paris Veltsos, Melissa A Toups, Nicolas Rodrigues, Roberto Sermier,
Daniel Jeffries, and Nicolas Perrin. “Tissue Specificity and Dynamics of Sex Biased
Gene Expression in a Common Frog Population with Differentiated, yet Homomorphic,
Sex Chromosomes.” Genes. MDPI AG, 2018. https://doi.org/10.3390/genes9060294.
ieee: W. Ma et al., “Tissue specificity and dynamics of sex biased gene expression
in a common frog population with differentiated, yet homomorphic, sex chromosomes,”
Genes, vol. 9, no. 6. MDPI AG, 2018.
ista: Ma W, Veltsos P, Toups MA, Rodrigues N, Sermier R, Jeffries D, Perrin N. 2018.
Tissue specificity and dynamics of sex biased gene expression in a common frog
population with differentiated, yet homomorphic, sex chromosomes. Genes. 9(6),
294.
mla: Ma, Wen, et al. “Tissue Specificity and Dynamics of Sex Biased Gene Expression
in a Common Frog Population with Differentiated, yet Homomorphic, Sex Chromosomes.”
Genes, vol. 9, no. 6, 294, MDPI AG, 2018, doi:10.3390/genes9060294.
short: W. Ma, P. Veltsos, M.A. Toups, N. Rodrigues, R. Sermier, D. Jeffries, N.
Perrin, Genes 9 (2018).
date_created: 2018-12-11T11:45:09Z
date_published: 2018-06-12T00:00:00Z
date_updated: 2023-09-19T10:15:31Z
day: '12'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.3390/genes9060294
external_id:
isi:
- '000436494200026'
file:
- access_level: open_access
checksum: 423069beb1cd3cdd25bf3f464b38f1d7
content_type: application/pdf
creator: dernst
date_created: 2019-02-01T07:52:28Z
date_updated: 2020-07-14T12:45:22Z
file_id: '5905'
file_name: 2018_Genes_Ma.pdf
file_size: 3985796
relation: main_file
file_date_updated: 2020-07-14T12:45:22Z
has_accepted_license: '1'
intvolume: ' 9'
isi: 1
issue: '6'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
publication: Genes
publication_status: published
publisher: MDPI AG
publist_id: '7714'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Tissue specificity and dynamics of sex biased gene expression in a common frog
population with differentiated, yet homomorphic, sex chromosomes
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 9
year: '2018'
...
---
_id: '543'
abstract:
- lang: eng
text: A central goal in theoretical neuroscience is to predict the response properties
of sensory neurons from first principles. To this end, “efficient coding” posits
that sensory neurons encode maximal information about their inputs given internal
constraints. There exist, however, many variants of efficient coding (e.g., redundancy
reduction, different formulations of predictive coding, robust coding, sparse
coding, etc.), differing in their regimes of applicability, in the relevance of
signals to be encoded, and in the choice of constraints. It is unclear how these
types of efficient coding relate or what is expected when different coding objectives
are combined. Here we present a unified framework that encompasses previously
proposed efficient coding models and extends to unique regimes. We show that optimizing
neural responses to encode predictive information can lead them to either correlate
or decorrelate their inputs, depending on the stimulus statistics; in contrast,
at low noise, efficiently encoding the past always predicts decorrelation. Later,
we investigate coding of naturalistic movies and show that qualitatively different
types of visual motion tuning and levels of response sparsity are predicted, depending
on whether the objective is to recover the past or predict the future. Our approach
promises a way to explain the observed diversity of sensory neural responses,
as due to multiple functional goals and constraints fulfilled by different cell
types and/or circuits.
article_processing_charge: No
author:
- first_name: Matthew J
full_name: Chalk, Matthew J
id: 2BAAC544-F248-11E8-B48F-1D18A9856A87
last_name: Chalk
orcid: 0000-0001-7782-4436
- first_name: Olivier
full_name: Marre, Olivier
last_name: Marre
- first_name: Gasper
full_name: Tkacik, Gasper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkacik
orcid: 0000-0002-6699-1455
citation:
ama: Chalk MJ, Marre O, Tkačik G. Toward a unified theory of efficient, predictive,
and sparse coding. PNAS. 2018;115(1):186-191. doi:10.1073/pnas.1711114115
apa: Chalk, M. J., Marre, O., & Tkačik, G. (2018). Toward a unified theory of
efficient, predictive, and sparse coding. PNAS. National Academy of Sciences.
https://doi.org/10.1073/pnas.1711114115
chicago: Chalk, Matthew J, Olivier Marre, and Gašper Tkačik. “Toward a Unified Theory
of Efficient, Predictive, and Sparse Coding.” PNAS. National Academy of
Sciences, 2018. https://doi.org/10.1073/pnas.1711114115.
ieee: M. J. Chalk, O. Marre, and G. Tkačik, “Toward a unified theory of efficient,
predictive, and sparse coding,” PNAS, vol. 115, no. 1. National Academy
of Sciences, pp. 186–191, 2018.
ista: Chalk MJ, Marre O, Tkačik G. 2018. Toward a unified theory of efficient, predictive,
and sparse coding. PNAS. 115(1), 186–191.
mla: Chalk, Matthew J., et al. “Toward a Unified Theory of Efficient, Predictive,
and Sparse Coding.” PNAS, vol. 115, no. 1, National Academy of Sciences,
2018, pp. 186–91, doi:10.1073/pnas.1711114115.
short: M.J. Chalk, O. Marre, G. Tkačik, PNAS 115 (2018) 186–191.
date_created: 2018-12-11T11:47:04Z
date_published: 2018-01-02T00:00:00Z
date_updated: 2023-09-19T10:16:35Z
day: '02'
department:
- _id: GaTk
doi: 10.1073/pnas.1711114115
external_id:
isi:
- '000419128700049'
intvolume: ' 115'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: 'https://doi.org/10.1101/152660 '
month: '01'
oa: 1
oa_version: Submitted Version
page: 186 - 191
project:
- _id: 254D1A94-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 25651-N26
name: Sensitivity to higher-order statistics in natural scenes
publication: PNAS
publication_status: published
publisher: National Academy of Sciences
publist_id: '7273'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Toward a unified theory of efficient, predictive, and sparse coding
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 115
year: '2018'
...
---
_id: '421'
abstract:
- lang: eng
text: Cell shape is determined by a balance of intrinsic properties of the cell
as well as its mechanochemical environment. Inhomogeneous shape changes underlie
many morphogenetic events and involve spatial gradients in active cellular forces
induced by complex chemical signaling. Here, we introduce a mechanochemical model
based on the notion that cell shape changes may be induced by external diffusible
biomolecules that influence cellular contractility (or equivalently, adhesions)
in a concentration-dependent manner—and whose spatial profile in turn is affected
by cell shape. We map out theoretically the possible interplay between chemical
concentration and cellular structure. Besides providing a direct route to spatial
gradients in cell shape profiles in tissues, we show that the dependence on cell
shape helps create robust mechanochemical gradients.
article_processing_charge: No
author:
- first_name: Kinjal
full_name: Dasbiswas, Kinjal
last_name: Dasbiswas
- first_name: Claude-Edouard B
full_name: Hannezo, Claude-Edouard B
id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
last_name: Hannezo
orcid: 0000-0001-6005-1561
- first_name: Nir
full_name: Gov, Nir
last_name: Gov
citation:
ama: Dasbiswas K, Hannezo EB, Gov N. Theory of eppithelial cell shape transitions
induced by mechanoactive chemical gradients. Biophysical Journal. 2018;114(4):968-977.
doi:10.1016/j.bpj.2017.12.022
apa: Dasbiswas, K., Hannezo, E. B., & Gov, N. (2018). Theory of eppithelial
cell shape transitions induced by mechanoactive chemical gradients. Biophysical
Journal. Biophysical Society. https://doi.org/10.1016/j.bpj.2017.12.022
chicago: Dasbiswas, Kinjal, Edouard B Hannezo, and Nir Gov. “Theory of Eppithelial
Cell Shape Transitions Induced by Mechanoactive Chemical Gradients.” Biophysical
Journal. Biophysical Society, 2018. https://doi.org/10.1016/j.bpj.2017.12.022.
ieee: K. Dasbiswas, E. B. Hannezo, and N. Gov, “Theory of eppithelial cell shape
transitions induced by mechanoactive chemical gradients,” Biophysical Journal,
vol. 114, no. 4. Biophysical Society, pp. 968–977, 2018.
ista: Dasbiswas K, Hannezo EB, Gov N. 2018. Theory of eppithelial cell shape transitions
induced by mechanoactive chemical gradients. Biophysical Journal. 114(4), 968–977.
mla: Dasbiswas, Kinjal, et al. “Theory of Eppithelial Cell Shape Transitions Induced
by Mechanoactive Chemical Gradients.” Biophysical Journal, vol. 114, no.
4, Biophysical Society, 2018, pp. 968–77, doi:10.1016/j.bpj.2017.12.022.
short: K. Dasbiswas, E.B. Hannezo, N. Gov, Biophysical Journal 114 (2018) 968–977.
date_created: 2018-12-11T11:46:23Z
date_published: 2018-02-27T00:00:00Z
date_updated: 2023-09-19T10:13:55Z
day: '27'
department:
- _id: EdHa
doi: 10.1016/j.bpj.2017.12.022
external_id:
arxiv:
- '1709.01486'
isi:
- '000428016700021'
intvolume: ' 114'
isi: 1
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1709.01486
month: '02'
oa: 1
oa_version: Submitted Version
page: 968 - 977
publication: Biophysical Journal
publication_status: published
publisher: Biophysical Society
publist_id: '7403'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Theory of eppithelial cell shape transitions induced by mechanoactive chemical
gradients
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 114
year: '2018'
...
---
_id: '63'
abstract:
- lang: eng
text: African cichlids display a remarkable assortment of jaw morphologies, pigmentation
patterns, and mating behaviors. In addition to this previously documented diversity,
recent studies have documented a rich diversity of sex chromosomes within these
fishes. Here we review the known sex-determination network within vertebrates,
and the extraordinary number of sex chromosomes systems segregating in African
cichlids. We also propose a model for understanding the unusual number of sex
chromosome systems within this clade.
acknowledgement: NSF DEB-1830753 and ISTPlus Fellowship
article_number: '480'
article_processing_charge: No
author:
- first_name: William J
full_name: Gammerdinger, William J
id: 3A7E01BC-F248-11E8-B48F-1D18A9856A87
last_name: Gammerdinger
orcid: 0000-0001-9638-1220
- first_name: Thomas
full_name: Kocher, Thomas
last_name: Kocher
citation:
ama: Gammerdinger WJ, Kocher T. Unusual diversity of sex chromosomes in African
cichlid fishes. Genes. 2018;9(10). doi:10.3390/genes9100480
apa: Gammerdinger, W. J., & Kocher, T. (2018). Unusual diversity of sex chromosomes
in African cichlid fishes. Genes. MDPI AG. https://doi.org/10.3390/genes9100480
chicago: Gammerdinger, William J, and Thomas Kocher. “Unusual Diversity of Sex Chromosomes
in African Cichlid Fishes.” Genes. MDPI AG, 2018. https://doi.org/10.3390/genes9100480.
ieee: W. J. Gammerdinger and T. Kocher, “Unusual diversity of sex chromosomes in
African cichlid fishes,” Genes, vol. 9, no. 10. MDPI AG, 2018.
ista: Gammerdinger WJ, Kocher T. 2018. Unusual diversity of sex chromosomes in African
cichlid fishes. Genes. 9(10), 480.
mla: Gammerdinger, William J., and Thomas Kocher. “Unusual Diversity of Sex Chromosomes
in African Cichlid Fishes.” Genes, vol. 9, no. 10, 480, MDPI AG, 2018,
doi:10.3390/genes9100480.
short: W.J. Gammerdinger, T. Kocher, Genes 9 (2018).
date_created: 2018-12-11T11:44:26Z
date_published: 2018-10-04T00:00:00Z
date_updated: 2023-09-19T10:37:03Z
day: '04'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.3390/genes9100480
ec_funded: 1
external_id:
isi:
- '000448656700018'
file:
- access_level: open_access
checksum: bec527692e2c9b56919c0429634ff337
content_type: application/pdf
creator: dernst
date_created: 2018-12-18T09:54:46Z
date_updated: 2020-07-14T12:47:27Z
file_id: '5743'
file_name: 2018_Genes_Gammerdinger.pdf
file_size: 1415791
relation: main_file
file_date_updated: 2020-07-14T12:47:27Z
has_accepted_license: '1'
intvolume: ' 9'
isi: 1
issue: '10'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Genes
publication_status: published
publisher: MDPI AG
publist_id: '7991'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Unusual diversity of sex chromosomes in African cichlid fishes
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 9
year: '2018'
...
---
_id: '296'
abstract:
- lang: eng
text: The thermodynamic description of many-particle systems rests on the assumption
of ergodicity, the ability of a system to explore all allowed configurations in
the phase space. Recent studies on many-body localization have revealed the existence
of systems that strongly violate ergodicity in the presence of quenched disorder.
Here, we demonstrate that ergodicity can be weakly broken by a different mechanism,
arising from the presence of special eigenstates in the many-body spectrum that
are reminiscent of quantum scars in chaotic non-interacting systems. In the single-particle
case, quantum scars correspond to wavefunctions that concentrate in the vicinity
of unstable periodic classical trajectories. We show that many-body scars appear
in the Fibonacci chain, a model with a constrained local Hilbert space that has
recently been experimentally realized in a Rydberg-atom quantum simulator. The
quantum scarred eigenstates are embedded throughout the otherwise thermalizing
many-body spectrum but lead to direct experimental signatures, as we show for
periodic recurrences that reproduce those observed in the experiment. Our results
suggest that scarred many-body bands give rise to a new universality class of
quantum dynamics, opening up opportunities for the creation of novel states with
long-lived coherence in systems that are now experimentally realizable.
acknowledgement: C.J.T., A.M. and Z.P. acknowledge support from EPSRC grants EP/P009409/1
and EP/M50807X/1, and Royal Society Research Grant RG160635. D.A. acknowledges support
from the Swiss National Science Foundation.
article_processing_charge: No
article_type: original
author:
- first_name: Christopher
full_name: Turner, Christopher
last_name: Turner
- first_name: Alexios
full_name: Michailidis, Alexios
id: 36EBAD38-F248-11E8-B48F-1D18A9856A87
last_name: Michailidis
orcid: 0000-0002-8443-1064
- first_name: Dmitry
full_name: Abanin, Dmitry
last_name: Abanin
- first_name: Maksym
full_name: Serbyn, Maksym
id: 47809E7E-F248-11E8-B48F-1D18A9856A87
last_name: Serbyn
orcid: 0000-0002-2399-5827
- first_name: Zlatko
full_name: Papić, Zlatko
last_name: Papić
citation:
ama: Turner C, Michailidis A, Abanin D, Serbyn M, Papić Z. Weak ergodicity breaking
from quantum many-body scars. Nature Physics. 2018;14:745-749. doi:10.1038/s41567-018-0137-5
apa: Turner, C., Michailidis, A., Abanin, D., Serbyn, M., & Papić, Z. (2018).
Weak ergodicity breaking from quantum many-body scars. Nature Physics.
Nature Publishing Group. https://doi.org/10.1038/s41567-018-0137-5
chicago: Turner, Christopher, Alexios Michailidis, Dmitry Abanin, Maksym Serbyn,
and Zlatko Papić. “Weak Ergodicity Breaking from Quantum Many-Body Scars.” Nature
Physics. Nature Publishing Group, 2018. https://doi.org/10.1038/s41567-018-0137-5.
ieee: C. Turner, A. Michailidis, D. Abanin, M. Serbyn, and Z. Papić, “Weak ergodicity
breaking from quantum many-body scars,” Nature Physics, vol. 14. Nature
Publishing Group, pp. 745–749, 2018.
ista: Turner C, Michailidis A, Abanin D, Serbyn M, Papić Z. 2018. Weak ergodicity
breaking from quantum many-body scars. Nature Physics. 14, 745–749.
mla: Turner, Christopher, et al. “Weak Ergodicity Breaking from Quantum Many-Body
Scars.” Nature Physics, vol. 14, Nature Publishing Group, 2018, pp. 745–49,
doi:10.1038/s41567-018-0137-5.
short: C. Turner, A. Michailidis, D. Abanin, M. Serbyn, Z. Papić, Nature Physics
14 (2018) 745–749.
date_created: 2018-12-11T11:45:40Z
date_published: 2018-05-14T00:00:00Z
date_updated: 2023-09-19T10:37:55Z
day: '14'
department:
- _id: MaSe
doi: 10.1038/s41567-018-0137-5
external_id:
isi:
- '000438253600028'
intvolume: ' 14'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://eprints.whiterose.ac.uk/130860/
month: '05'
oa: 1
oa_version: Submitted Version
page: 745 - 749
publication: Nature Physics
publication_status: published
publisher: Nature Publishing Group
publist_id: '7585'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Weak ergodicity breaking from quantum many-body scars
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 14
year: '2018'
...
---
_id: '607'
abstract:
- lang: eng
text: We study the Fokker-Planck equation derived in the large system limit of the
Markovian process describing the dynamics of quantitative traits. The Fokker-Planck
equation is posed on a bounded domain and its transport and diffusion coefficients
vanish on the domain's boundary. We first argue that, despite this degeneracy,
the standard no-flux boundary condition is valid. We derive the weak formulation
of the problem and prove the existence and uniqueness of its solutions by constructing
the corresponding contraction semigroup on a suitable function space. Then, we
prove that for the parameter regime with high enough mutation rate the problem
exhibits a positive spectral gap, which implies exponential convergence to equilibrium.Next,
we provide a simple derivation of the so-called Dynamic Maximum Entropy (DynMaxEnt)
method for approximation of observables (moments) of the Fokker-Planck solution,
which can be interpreted as a nonlinear Galerkin approximation. The limited applicability
of the DynMaxEnt method inspires us to introduce its modified version that is
valid for the whole range of admissible parameters. Finally, we present several
numerical experiments to demonstrate the performance of both the original and
modified DynMaxEnt methods. We observe that in the parameter regimes where both
methods are valid, the modified one exhibits slightly better approximation properties
compared to the original one.
acknowledgement: "JH and PM are funded by KAUST baseline funds and grant no. 1000000193
.\r\nWe thank Nicholas Barton (IST Austria) for his useful comments and suggestions.
\r\n\r\n"
article_processing_charge: No
author:
- first_name: Katarina
full_name: Bodova, Katarina
id: 2BA24EA0-F248-11E8-B48F-1D18A9856A87
last_name: Bodova
orcid: 0000-0002-7214-0171
- first_name: Jan
full_name: Haskovec, Jan
last_name: Haskovec
- first_name: Peter
full_name: Markowich, Peter
last_name: Markowich
citation:
ama: 'Bodova K, Haskovec J, Markowich P. Well posedness and maximum entropy approximation
for the dynamics of quantitative traits. Physica D: Nonlinear Phenomena.
2018;376-377:108-120. doi:10.1016/j.physd.2017.10.015'
apa: 'Bodova, K., Haskovec, J., & Markowich, P. (2018). Well posedness and maximum
entropy approximation for the dynamics of quantitative traits. Physica D: Nonlinear
Phenomena. Elsevier. https://doi.org/10.1016/j.physd.2017.10.015'
chicago: 'Bodova, Katarina, Jan Haskovec, and Peter Markowich. “Well Posedness and
Maximum Entropy Approximation for the Dynamics of Quantitative Traits.” Physica
D: Nonlinear Phenomena. Elsevier, 2018. https://doi.org/10.1016/j.physd.2017.10.015.'
ieee: 'K. Bodova, J. Haskovec, and P. Markowich, “Well posedness and maximum entropy
approximation for the dynamics of quantitative traits,” Physica D: Nonlinear
Phenomena, vol. 376–377. Elsevier, pp. 108–120, 2018.'
ista: 'Bodova K, Haskovec J, Markowich P. 2018. Well posedness and maximum entropy
approximation for the dynamics of quantitative traits. Physica D: Nonlinear Phenomena.
376–377, 108–120.'
mla: 'Bodova, Katarina, et al. “Well Posedness and Maximum Entropy Approximation
for the Dynamics of Quantitative Traits.” Physica D: Nonlinear Phenomena,
vol. 376–377, Elsevier, 2018, pp. 108–20, doi:10.1016/j.physd.2017.10.015.'
short: 'K. Bodova, J. Haskovec, P. Markowich, Physica D: Nonlinear Phenomena 376–377
(2018) 108–120.'
date_created: 2018-12-11T11:47:28Z
date_published: 2018-08-01T00:00:00Z
date_updated: 2023-09-19T10:38:34Z
day: '01'
department:
- _id: NiBa
- _id: GaTk
doi: 10.1016/j.physd.2017.10.015
external_id:
arxiv:
- '1704.08757'
isi:
- '000437962900012'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1704.08757
month: '08'
oa: 1
oa_version: Submitted Version
page: 108-120
publication: 'Physica D: Nonlinear Phenomena'
publication_status: published
publisher: Elsevier
publist_id: '7198'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Well posedness and maximum entropy approximation for the dynamics of quantitative
traits
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 376-377
year: '2018'
...
---
_id: '294'
abstract:
- lang: eng
text: We developed a method to calculate two-photon processes in quantum mechanics
that replaces the infinite summation over the intermediate states by a perturbation
expansion. This latter consists of a series of commutators that involve position,
momentum, and Hamiltonian quantum operators. We analyzed several single- and many-particle
cases for which a closed-form solution to the perturbation expansion exists, as
well as more complicated cases for which a solution is found by convergence. Throughout
the article, Rayleigh and Raman scattering are taken as examples of two-photon
processes. The present method provides a clear distinction between the Thomson
scattering, regarded as classical scattering, and quantum contributions. Such
a distinction lets us derive general results concerning light scattering. Finally,
possible extensions to the developed formalism are discussed.
article_processing_charge: No
author:
- first_name: Filippo
full_name: Fratini, Filippo
last_name: Fratini
- first_name: Laleh
full_name: Safari, Laleh
id: 3C325E5E-F248-11E8-B48F-1D18A9856A87
last_name: Safari
- first_name: Pedro
full_name: Amaro, Pedro
last_name: Amaro
- first_name: José
full_name: Santos, José
last_name: Santos
citation:
ama: Fratini F, Safari L, Amaro P, Santos J. Two-photon processes based on quantum
commutators. Physical Review A - Atomic, Molecular, and Optical Physics.
2018;97(4). doi:10.1103/PhysRevA.97.043842
apa: Fratini, F., Safari, L., Amaro, P., & Santos, J. (2018). Two-photon processes
based on quantum commutators. Physical Review A - Atomic, Molecular, and Optical
Physics. American Physical Society. https://doi.org/10.1103/PhysRevA.97.043842
chicago: Fratini, Filippo, Laleh Safari, Pedro Amaro, and José Santos. “Two-Photon
Processes Based on Quantum Commutators.” Physical Review A - Atomic, Molecular,
and Optical Physics. American Physical Society, 2018. https://doi.org/10.1103/PhysRevA.97.043842.
ieee: F. Fratini, L. Safari, P. Amaro, and J. Santos, “Two-photon processes based
on quantum commutators,” Physical Review A - Atomic, Molecular, and Optical
Physics, vol. 97, no. 4. American Physical Society, 2018.
ista: Fratini F, Safari L, Amaro P, Santos J. 2018. Two-photon processes based on
quantum commutators. Physical Review A - Atomic, Molecular, and Optical Physics.
97(4).
mla: Fratini, Filippo, et al. “Two-Photon Processes Based on Quantum Commutators.”
Physical Review A - Atomic, Molecular, and Optical Physics, vol. 97, no.
4, American Physical Society, 2018, doi:10.1103/PhysRevA.97.043842.
short: F. Fratini, L. Safari, P. Amaro, J. Santos, Physical Review A - Atomic, Molecular,
and Optical Physics 97 (2018).
date_created: 2018-12-11T11:45:40Z
date_published: 2018-04-18T00:00:00Z
date_updated: 2023-09-19T10:17:56Z
day: '18'
department:
- _id: MiLe
doi: 10.1103/PhysRevA.97.043842
ec_funded: 1
external_id:
arxiv:
- '1801.06892'
isi:
- '000430296800008'
intvolume: ' 97'
isi: 1
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1801.06892
month: '04'
oa: 1
oa_version: Submitted Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Physical Review A - Atomic, Molecular, and Optical Physics
publication_status: published
publisher: American Physical Society
publist_id: '7587'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Two-photon processes based on quantum commutators
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 97
year: '2018'
...
---
_id: '606'
abstract:
- lang: eng
text: We establish the existence of a global solution for a new family of fluid-like
equations, which are obtained in certain regimes in as the mean-field evolution
of the supercurrent density in a (2D section of a) type-II superconductor with
pinning and with imposed electric current. We also consider general vortex-sheet
initial data, and investigate the uniqueness and regularity properties of the
solution. For some choice of parameters, the equation under investigation coincides
with the so-called lake equation from 2D shallow water fluid dynamics, and our
analysis then leads to a new existence result for rough initial data.
acknowledgement: "The work of the author is supported by F.R.S.-FNRS ( Fonds de la
Recherche Scientifique - FNRS ) through a Research Fellowship.\r\n\r\n"
article_processing_charge: No
author:
- first_name: Mitia
full_name: Duerinckx, Mitia
last_name: Duerinckx
- first_name: Julian L
full_name: Fischer, Julian L
id: 2C12A0B0-F248-11E8-B48F-1D18A9856A87
last_name: Fischer
orcid: 0000-0002-0479-558X
citation:
ama: Duerinckx M, Fischer JL. Well-posedness for mean-field evolutions arising in
superconductivity. Annales de l’Institut Henri Poincare (C) Non Linear Analysis.
2018;35(5):1267-1319. doi:10.1016/j.anihpc.2017.11.004
apa: Duerinckx, M., & Fischer, J. L. (2018). Well-posedness for mean-field evolutions
arising in superconductivity. Annales de l’Institut Henri Poincare (C) Non
Linear Analysis. Elsevier. https://doi.org/10.1016/j.anihpc.2017.11.004
chicago: Duerinckx, Mitia, and Julian L Fischer. “Well-Posedness for Mean-Field
Evolutions Arising in Superconductivity.” Annales de l’Institut Henri Poincare
(C) Non Linear Analysis. Elsevier, 2018. https://doi.org/10.1016/j.anihpc.2017.11.004.
ieee: M. Duerinckx and J. L. Fischer, “Well-posedness for mean-field evolutions
arising in superconductivity,” Annales de l’Institut Henri Poincare (C) Non
Linear Analysis, vol. 35, no. 5. Elsevier, pp. 1267–1319, 2018.
ista: Duerinckx M, Fischer JL. 2018. Well-posedness for mean-field evolutions arising
in superconductivity. Annales de l’Institut Henri Poincare (C) Non Linear Analysis.
35(5), 1267–1319.
mla: Duerinckx, Mitia, and Julian L. Fischer. “Well-Posedness for Mean-Field Evolutions
Arising in Superconductivity.” Annales de l’Institut Henri Poincare (C) Non
Linear Analysis, vol. 35, no. 5, Elsevier, 2018, pp. 1267–319, doi:10.1016/j.anihpc.2017.11.004.
short: M. Duerinckx, J.L. Fischer, Annales de l’Institut Henri Poincare (C) Non
Linear Analysis 35 (2018) 1267–1319.
date_created: 2018-12-11T11:47:27Z
date_published: 2018-08-01T00:00:00Z
date_updated: 2023-09-19T10:39:09Z
day: '01'
department:
- _id: JuFi
doi: 10.1016/j.anihpc.2017.11.004
external_id:
arxiv:
- '1607.00268'
isi:
- '000437975500005'
intvolume: ' 35'
isi: 1
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1607.00268
month: '08'
oa: 1
oa_version: Submitted Version
page: 1267-1319
publication: Annales de l'Institut Henri Poincare (C) Non Linear Analysis
publication_status: published
publisher: Elsevier
publist_id: '7199'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Well-posedness for mean-field evolutions arising in superconductivity
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 35
year: '2018'
...
---
_id: '5959'
abstract:
- lang: eng
text: Formalizing properties of systems with continuous dynamics is a challenging
task. In this paper, we propose a formal framework for specifying and monitoring
rich temporal properties of real-valued signals. We introduce signal first-order
logic (SFO) as a specification language that combines first-order logic with linear-real
arithmetic and unary function symbols interpreted as piecewise-linear signals.
We first show that while the satisfiability problem for SFO is undecidable, its
membership and monitoring problems are decidable. We develop an offline monitoring
procedure for SFO that has polynomial complexity in the size of the input trace
and the specification, for a fixed number of quantifiers and function symbols.
We show that the algorithm has computation time linear in the size of the input
trace for the important fragment of bounded-response specifications interpreted
over input traces with finite variability. We can use our results to extend signal
temporal logic with first-order quantifiers over time and value parameters, while
preserving its efficient monitoring. We finally demonstrate the practical appeal
of our logic through a case study in the micro-electronics domain.
article_processing_charge: No
author:
- first_name: Alexey
full_name: Bakhirkin, Alexey
last_name: Bakhirkin
- first_name: Thomas
full_name: Ferrere, Thomas
id: 40960E6E-F248-11E8-B48F-1D18A9856A87
last_name: Ferrere
orcid: 0000-0001-5199-3143
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Deian
full_name: Nickovicl, Deian
last_name: Nickovicl
citation:
ama: 'Bakhirkin A, Ferrere T, Henzinger TA, Nickovicl D. Keynote: The first-order
logic of signals. In: 2018 International Conference on Embedded Software.
IEEE; 2018:1-10. doi:10.1109/emsoft.2018.8537203'
apa: 'Bakhirkin, A., Ferrere, T., Henzinger, T. A., & Nickovicl, D. (2018).
Keynote: The first-order logic of signals. In 2018 International Conference
on Embedded Software (pp. 1–10). Turin, Italy: IEEE. https://doi.org/10.1109/emsoft.2018.8537203'
chicago: 'Bakhirkin, Alexey, Thomas Ferrere, Thomas A Henzinger, and Deian Nickovicl.
“Keynote: The First-Order Logic of Signals.” In 2018 International Conference
on Embedded Software, 1–10. IEEE, 2018. https://doi.org/10.1109/emsoft.2018.8537203.'
ieee: 'A. Bakhirkin, T. Ferrere, T. A. Henzinger, and D. Nickovicl, “Keynote: The
first-order logic of signals,” in 2018 International Conference on Embedded
Software, Turin, Italy, 2018, pp. 1–10.'
ista: 'Bakhirkin A, Ferrere T, Henzinger TA, Nickovicl D. 2018. Keynote: The first-order
logic of signals. 2018 International Conference on Embedded Software. EMSOFT:
International Conference on Embedded Software, 1–10.'
mla: 'Bakhirkin, Alexey, et al. “Keynote: The First-Order Logic of Signals.” 2018
International Conference on Embedded Software, IEEE, 2018, pp. 1–10, doi:10.1109/emsoft.2018.8537203.'
short: A. Bakhirkin, T. Ferrere, T.A. Henzinger, D. Nickovicl, in:, 2018 International
Conference on Embedded Software, IEEE, 2018, pp. 1–10.
conference:
end_date: 2018-10-05
location: Turin, Italy
name: 'EMSOFT: International Conference on Embedded Software'
start_date: 2018-09-30
date_created: 2019-02-13T09:19:28Z
date_published: 2018-09-30T00:00:00Z
date_updated: 2023-09-19T10:41:29Z
day: '30'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.1109/emsoft.2018.8537203
external_id:
isi:
- '000492828500005'
file:
- access_level: open_access
checksum: 234a33ad9055b3458fcdda6af251b33a
content_type: application/pdf
creator: dernst
date_created: 2020-05-14T16:01:29Z
date_updated: 2020-07-14T12:47:13Z
file_id: '7839'
file_name: 2018_EMSOFT_Bakhirkin.pdf
file_size: 338006
relation: main_file
file_date_updated: 2020-07-14T12:47:13Z
has_accepted_license: '1'
isi: 1
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: 1-10
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
publication: 2018 International Conference on Embedded Software
publication_identifier:
isbn:
- '9781538655603'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Keynote: The first-order logic of signals'
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '5962'
abstract:
- lang: eng
text: Stochastic Gradient Descent (SGD) is a fundamental algorithm in machine learning,
representing the optimization backbone for training several classic models, from
regression to neural networks. Given the recent practical focus on distributed
machine learning, significant work has been dedicated to the convergence properties
of this algorithm under the inconsistent and noisy updates arising from execution
in a distributed environment. However, surprisingly, the convergence properties
of this classic algorithm in the standard shared-memory model are still not well-understood.
In this work, we address this gap, and provide new convergence bounds for lock-free
concurrent stochastic gradient descent, executing in the classic asynchronous
shared memory model, against a strong adaptive adversary. Our results give improved
upper and lower bounds on the "price of asynchrony'' when executing the fundamental
SGD algorithm in a concurrent setting. They show that this classic optimization
tool can converge faster and with a wider range of parameters than previously
known under asynchronous iterations. At the same time, we exhibit a fundamental
trade-off between the maximum delay in the system and the rate at which SGD can
converge, which governs the set of parameters under which this algorithm can still
work efficiently.
article_processing_charge: No
author:
- first_name: Dan-Adrian
full_name: Alistarh, Dan-Adrian
id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
last_name: Alistarh
orcid: 0000-0003-3650-940X
- first_name: Christopher
full_name: De Sa, Christopher
last_name: De Sa
- first_name: Nikola H
full_name: Konstantinov, Nikola H
id: 4B9D76E4-F248-11E8-B48F-1D18A9856A87
last_name: Konstantinov
citation:
ama: 'Alistarh D-A, De Sa C, Konstantinov NH. The convergence of stochastic gradient
descent in asynchronous shared memory. In: Proceedings of the 2018 ACM Symposium
on Principles of Distributed Computing - PODC ’18. ACM Press; 2018:169-178.
doi:10.1145/3212734.3212763'
apa: 'Alistarh, D.-A., De Sa, C., & Konstantinov, N. H. (2018). The convergence
of stochastic gradient descent in asynchronous shared memory. In Proceedings
of the 2018 ACM Symposium on Principles of Distributed Computing - PODC ’18
(pp. 169–178). Egham, United Kingdom: ACM Press. https://doi.org/10.1145/3212734.3212763'
chicago: Alistarh, Dan-Adrian, Christopher De Sa, and Nikola H Konstantinov. “The
Convergence of Stochastic Gradient Descent in Asynchronous Shared Memory.” In
Proceedings of the 2018 ACM Symposium on Principles of Distributed Computing
- PODC ’18, 169–78. ACM Press, 2018. https://doi.org/10.1145/3212734.3212763.
ieee: D.-A. Alistarh, C. De Sa, and N. H. Konstantinov, “The convergence of stochastic
gradient descent in asynchronous shared memory,” in Proceedings of the 2018
ACM Symposium on Principles of Distributed Computing - PODC ’18, Egham, United
Kingdom, 2018, pp. 169–178.
ista: 'Alistarh D-A, De Sa C, Konstantinov NH. 2018. The convergence of stochastic
gradient descent in asynchronous shared memory. Proceedings of the 2018 ACM Symposium
on Principles of Distributed Computing - PODC ’18. PODC: Principles of Distributed
Computing, 169–178.'
mla: Alistarh, Dan-Adrian, et al. “The Convergence of Stochastic Gradient Descent
in Asynchronous Shared Memory.” Proceedings of the 2018 ACM Symposium on Principles
of Distributed Computing - PODC ’18, ACM Press, 2018, pp. 169–78, doi:10.1145/3212734.3212763.
short: D.-A. Alistarh, C. De Sa, N.H. Konstantinov, in:, Proceedings of the 2018
ACM Symposium on Principles of Distributed Computing - PODC ’18, ACM Press, 2018,
pp. 169–178.
conference:
end_date: 2018-07-27
location: Egham, United Kingdom
name: 'PODC: Principles of Distributed Computing'
start_date: 2018-07-23
date_created: 2019-02-13T09:58:58Z
date_published: 2018-07-23T00:00:00Z
date_updated: 2023-09-19T10:42:53Z
day: '23'
department:
- _id: DaAl
doi: 10.1145/3212734.3212763
external_id:
arxiv:
- '1803.08841'
isi:
- '000458186900022'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1803.08841
month: '07'
oa: 1
oa_version: Preprint
page: 169-178
publication: Proceedings of the 2018 ACM Symposium on Principles of Distributed Computing -
PODC '18
publication_identifier:
isbn:
- '9781450357951'
publication_status: published
publisher: ACM Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: The convergence of stochastic gradient descent in asynchronous shared memory
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '5860'
abstract:
- lang: eng
text: 'A major problem for evolutionary theory is understanding the so-called open-ended
nature of evolutionary change, from its definition to its origins. Open-ended
evolution (OEE) refers to the unbounded increase in complexity that seems to characterize
evolution on multiple scales. This property seems to be a characteristic feature
of biological and technological evolution and is strongly tied to the generative
potential associated with combinatorics, which allows the system to grow and expand
their available state spaces. Interestingly, many complex systems presumably displaying
OEE, from language to proteins, share a common statistical property: the presence
of Zipf''s Law. Given an inventory of basic items (such as words or protein domains)
required to build more complex structures (sentences or proteins) Zipf''s Law
tells us that most of these elements are rare whereas a few of them are extremely
common. Using algorithmic information theory, in this paper we provide a fundamental
definition for open-endedness, which can be understood as postulates. Its statistical
counterpart, based on standard Shannon information theory, has the structure of
a variational problem which is shown to lead to Zipf''s Law as the expected consequence
of an evolutionary process displaying OEE. We further explore the problem of information
conservation through an OEE process and we conclude that statistical information
(standard Shannon information) is not conserved, resulting in the paradoxical
situation in which the increase of information content has the effect of erasing
itself. We prove that this paradox is solved if we consider non-statistical forms
of information. This last result implies that standard information theory may
not be a suitable theoretical framework to explore the persistence and increase
of the information content in OEE systems.'
article_number: '20180395'
article_processing_charge: No
author:
- first_name: Bernat
full_name: Corominas-Murtra, Bernat
id: 43BE2298-F248-11E8-B48F-1D18A9856A87
last_name: Corominas-Murtra
orcid: 0000-0001-9806-5643
- first_name: Luís F.
full_name: Seoane, Luís F.
last_name: Seoane
- first_name: Ricard
full_name: Solé, Ricard
last_name: Solé
citation:
ama: Corominas-Murtra B, Seoane LF, Solé R. Zipf’s Law, unbounded complexity and
open-ended evolution. Journal of the Royal Society Interface. 2018;15(149).
doi:10.1098/rsif.2018.0395
apa: Corominas-Murtra, B., Seoane, L. F., & Solé, R. (2018). Zipf’s Law, unbounded
complexity and open-ended evolution. Journal of the Royal Society Interface.
Royal Society Publishing. https://doi.org/10.1098/rsif.2018.0395
chicago: Corominas-Murtra, Bernat, Luís F. Seoane, and Ricard Solé. “Zipf’s Law,
Unbounded Complexity and Open-Ended Evolution.” Journal of the Royal Society
Interface. Royal Society Publishing, 2018. https://doi.org/10.1098/rsif.2018.0395.
ieee: B. Corominas-Murtra, L. F. Seoane, and R. Solé, “Zipf’s Law, unbounded complexity
and open-ended evolution,” Journal of the Royal Society Interface, vol.
15, no. 149. Royal Society Publishing, 2018.
ista: Corominas-Murtra B, Seoane LF, Solé R. 2018. Zipf’s Law, unbounded complexity
and open-ended evolution. Journal of the Royal Society Interface. 15(149), 20180395.
mla: Corominas-Murtra, Bernat, et al. “Zipf’s Law, Unbounded Complexity and Open-Ended
Evolution.” Journal of the Royal Society Interface, vol. 15, no. 149, 20180395,
Royal Society Publishing, 2018, doi:10.1098/rsif.2018.0395.
short: B. Corominas-Murtra, L.F. Seoane, R. Solé, Journal of the Royal Society Interface
15 (2018).
date_created: 2019-01-20T22:59:19Z
date_published: 2018-12-12T00:00:00Z
date_updated: 2023-09-19T10:40:38Z
day: '12'
department:
- _id: EdHa
doi: 10.1098/rsif.2018.0395
external_id:
arxiv:
- '1612.01605'
isi:
- '000456783800002'
intvolume: ' 15'
isi: 1
issue: '149'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1612.01605
month: '12'
oa: 1
oa_version: Preprint
publication: Journal of the Royal Society Interface
publication_identifier:
issn:
- '17425689'
publication_status: published
publisher: Royal Society Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Zipf's Law, unbounded complexity and open-ended evolution
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 15
year: '2018'
...
---
_id: '5961'
abstract:
- lang: eng
text: "The area of machine learning has made considerable progress over the past
decade, enabled by the widespread availability of large datasets, as well as by
improved algorithms and models. Given the large computational demands of machine
learning workloads, parallelism, implemented either through single-node concurrency
or through multi-node distribution, has been a third key ingredient to advances
in machine learning.\r\nThe goal of this tutorial is to provide the audience with
an overview of standard distribution techniques in machine learning, with an eye
towards the intriguing trade-offs between synchronization and communication costs
of distributed machine learning algorithms, on the one hand, and their convergence,
on the other.The tutorial will focus on parallelization strategies for the fundamental
stochastic gradient descent (SGD) algorithm, which is a key tool when training
machine learning models, from classical instances such as linear regression, to
state-of-the-art neural network architectures.\r\nThe tutorial will describe the
guarantees provided by this algorithm in the sequential case, and then move on
to cover both shared-memory and message-passing parallelization strategies, together
with the guarantees they provide, and corresponding trade-offs. The presentation
will conclude with a broad overview of ongoing research in distributed and concurrent
machine learning. The tutorial will assume no prior knowledge beyond familiarity
with basic concepts in algebra and analysis.\r\n"
article_processing_charge: No
author:
- first_name: Dan-Adrian
full_name: Alistarh, Dan-Adrian
id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
last_name: Alistarh
orcid: 0000-0003-3650-940X
citation:
ama: 'Alistarh D-A. A brief tutorial on distributed and concurrent machine learning.
In: Proceedings of the 2018 ACM Symposium on Principles of Distributed Computing
- PODC ’18. ACM Press; 2018:487-488. doi:10.1145/3212734.3212798'
apa: 'Alistarh, D.-A. (2018). A brief tutorial on distributed and concurrent machine
learning. In Proceedings of the 2018 ACM Symposium on Principles of Distributed
Computing - PODC ’18 (pp. 487–488). Egham, United Kingdom: ACM Press. https://doi.org/10.1145/3212734.3212798'
chicago: Alistarh, Dan-Adrian. “A Brief Tutorial on Distributed and Concurrent Machine
Learning.” In Proceedings of the 2018 ACM Symposium on Principles of Distributed
Computing - PODC ’18, 487–88. ACM Press, 2018. https://doi.org/10.1145/3212734.3212798.
ieee: D.-A. Alistarh, “A brief tutorial on distributed and concurrent machine learning,”
in Proceedings of the 2018 ACM Symposium on Principles of Distributed Computing
- PODC ’18, Egham, United Kingdom, 2018, pp. 487–488.
ista: 'Alistarh D-A. 2018. A brief tutorial on distributed and concurrent machine
learning. Proceedings of the 2018 ACM Symposium on Principles of Distributed Computing
- PODC ’18. PODC: Principles of Distributed Computing, 487–488.'
mla: Alistarh, Dan-Adrian. “A Brief Tutorial on Distributed and Concurrent Machine
Learning.” Proceedings of the 2018 ACM Symposium on Principles of Distributed
Computing - PODC ’18, ACM Press, 2018, pp. 487–88, doi:10.1145/3212734.3212798.
short: D.-A. Alistarh, in:, Proceedings of the 2018 ACM Symposium on Principles
of Distributed Computing - PODC ’18, ACM Press, 2018, pp. 487–488.
conference:
end_date: 2018-07-27
location: Egham, United Kingdom
name: 'PODC: Principles of Distributed Computing'
start_date: 2018-07-23
date_created: 2019-02-13T09:48:55Z
date_published: 2018-07-27T00:00:00Z
date_updated: 2023-09-19T10:42:28Z
day: '27'
department:
- _id: DaAl
doi: 10.1145/3212734.3212798
external_id:
isi:
- '000458186900063'
isi: 1
language:
- iso: eng
month: '07'
oa_version: None
page: 487-488
publication: Proceedings of the 2018 ACM Symposium on Principles of Distributed Computing -
PODC '18
publication_identifier:
isbn:
- '9781450357951'
publication_status: published
publisher: ACM Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: A brief tutorial on distributed and concurrent machine learning
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '5960'
abstract:
- lang: eng
text: In this paper we present a reliable method to verify the existence of loops
along the uncertain trajectory of a robot, based on proprioceptive measurements
only, within a bounded-error context. The loop closure detection is one of the
key points in simultaneous localization and mapping (SLAM) methods, especially
in homogeneous environments with difficult scenes recognitions. The proposed approach
is generic and could be coupled with conventional SLAM algorithms to reliably
reduce their computing burden, thus improving the localization and mapping processes
in the most challenging environments such as unexplored underwater extents. To
prove that a robot performed a loop whatever the uncertainties in its evolution,
we employ the notion of topological degree that originates in the field of differential
topology. We show that a verification tool based on the topological degree is
an optimal method for proving robot loops. This is demonstrated both on datasets
from real missions involving autonomous underwater vehicles and by a mathematical
discussion.
article_processing_charge: No
author:
- first_name: Simon
full_name: Rohou, Simon
last_name: Rohou
- first_name: Peter
full_name: Franek, Peter
id: 473294AE-F248-11E8-B48F-1D18A9856A87
last_name: Franek
orcid: 0000-0001-8878-8397
- first_name: Clément
full_name: Aubry, Clément
last_name: Aubry
- first_name: Luc
full_name: Jaulin, Luc
last_name: Jaulin
citation:
ama: Rohou S, Franek P, Aubry C, Jaulin L. Proving the existence of loops in robot
trajectories. The International Journal of Robotics Research. 2018;37(12):1500-1516.
doi:10.1177/0278364918808367
apa: Rohou, S., Franek, P., Aubry, C., & Jaulin, L. (2018). Proving the existence
of loops in robot trajectories. The International Journal of Robotics Research.
SAGE Publications. https://doi.org/10.1177/0278364918808367
chicago: Rohou, Simon, Peter Franek, Clément Aubry, and Luc Jaulin. “Proving the
Existence of Loops in Robot Trajectories.” The International Journal of Robotics
Research. SAGE Publications, 2018. https://doi.org/10.1177/0278364918808367.
ieee: S. Rohou, P. Franek, C. Aubry, and L. Jaulin, “Proving the existence of loops
in robot trajectories,” The International Journal of Robotics Research,
vol. 37, no. 12. SAGE Publications, pp. 1500–1516, 2018.
ista: Rohou S, Franek P, Aubry C, Jaulin L. 2018. Proving the existence of loops
in robot trajectories. The International Journal of Robotics Research. 37(12),
1500–1516.
mla: Rohou, Simon, et al. “Proving the Existence of Loops in Robot Trajectories.”
The International Journal of Robotics Research, vol. 37, no. 12, SAGE Publications,
2018, pp. 1500–16, doi:10.1177/0278364918808367.
short: S. Rohou, P. Franek, C. Aubry, L. Jaulin, The International Journal of Robotics
Research 37 (2018) 1500–1516.
date_created: 2019-02-13T09:36:20Z
date_published: 2018-10-24T00:00:00Z
date_updated: 2023-09-19T10:41:59Z
day: '24'
department:
- _id: UlWa
doi: 10.1177/0278364918808367
external_id:
arxiv:
- '1712.01341'
isi:
- '000456881100004'
intvolume: ' 37'
isi: 1
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1712.01341
month: '10'
oa: 1
oa_version: Preprint
page: 1500-1516
publication: The International Journal of Robotics Research
publication_identifier:
eissn:
- 1741-3176
issn:
- 0278-3649
publication_status: published
publisher: SAGE Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: Proving the existence of loops in robot trajectories
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 37
year: '2018'
...
---
_id: '5963'
abstract:
- lang: eng
text: 'There has been significant progress in understanding the parallelism inherent
to iterative sequential algorithms: for many classic algorithms, the depth of
the dependence structure is now well understood, and scheduling techniques have
been developed to exploit this shallow dependence structure for efficient parallel
implementations. A related, applied research strand has studied methods by which
certain iterative task-based algorithms can be efficiently parallelized via relaxed
concurrent priority schedulers. These allow for high concurrency when inserting
and removing tasks, at the cost of executing superfluous work due to the relaxed
semantics of the scheduler. In this work, we take a step towards unifying these
two research directions, by showing that there exists a family of relaxed priority
schedulers that can efficiently and deterministically execute classic iterative
algorithms such as greedy maximal independent set (MIS) and matching. Our primary
result shows that, given a randomized scheduler with an expected relaxation factor
of k in terms of the maximum allowed priority inversions on a task, and any graph
on n vertices, the scheduler is able to execute greedy MIS with only an additive
factor of \poly(k) expected additional iterations compared to an exact (but not
scalable) scheduler. This counter-intuitive result demonstrates that the overhead
of relaxation when computing MIS is not dependent on the input size or structure
of the input graph. Experimental results show that this overhead can be clearly
offset by the gain in performance due to the highly scalable scheduler. In sum,
we present an efficient method to deterministically parallelize iterative sequential
algorithms, with provable runtime guarantees in terms of the number of executed
tasks to completion.'
article_processing_charge: No
author:
- first_name: Dan-Adrian
full_name: Alistarh, Dan-Adrian
id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
last_name: Alistarh
orcid: 0000-0003-3650-940X
- first_name: Trevor A
full_name: Brown, Trevor A
id: 3569F0A0-F248-11E8-B48F-1D18A9856A87
last_name: Brown
- first_name: Justin
full_name: Kopinsky, Justin
last_name: Kopinsky
- first_name: Giorgi
full_name: Nadiradze, Giorgi
last_name: Nadiradze
citation:
ama: 'Alistarh D-A, Brown TA, Kopinsky J, Nadiradze G. Relaxed schedulers can efficiently
parallelize iterative algorithms. In: Proceedings of the 2018 ACM Symposium
on Principles of Distributed Computing - PODC ’18. ACM Press; 2018:377-386.
doi:10.1145/3212734.3212756'
apa: 'Alistarh, D.-A., Brown, T. A., Kopinsky, J., & Nadiradze, G. (2018). Relaxed
schedulers can efficiently parallelize iterative algorithms. In Proceedings
of the 2018 ACM Symposium on Principles of Distributed Computing - PODC ’18
(pp. 377–386). Egham, United Kingdom: ACM Press. https://doi.org/10.1145/3212734.3212756'
chicago: Alistarh, Dan-Adrian, Trevor A Brown, Justin Kopinsky, and Giorgi Nadiradze.
“Relaxed Schedulers Can Efficiently Parallelize Iterative Algorithms.” In Proceedings
of the 2018 ACM Symposium on Principles of Distributed Computing - PODC ’18,
377–86. ACM Press, 2018. https://doi.org/10.1145/3212734.3212756.
ieee: D.-A. Alistarh, T. A. Brown, J. Kopinsky, and G. Nadiradze, “Relaxed schedulers
can efficiently parallelize iterative algorithms,” in Proceedings of the 2018
ACM Symposium on Principles of Distributed Computing - PODC ’18, Egham, United
Kingdom, 2018, pp. 377–386.
ista: 'Alistarh D-A, Brown TA, Kopinsky J, Nadiradze G. 2018. Relaxed schedulers
can efficiently parallelize iterative algorithms. Proceedings of the 2018 ACM
Symposium on Principles of Distributed Computing - PODC ’18. PODC: Principles
of Distributed Computing, 377–386.'
mla: Alistarh, Dan-Adrian, et al. “Relaxed Schedulers Can Efficiently Parallelize
Iterative Algorithms.” Proceedings of the 2018 ACM Symposium on Principles
of Distributed Computing - PODC ’18, ACM Press, 2018, pp. 377–86, doi:10.1145/3212734.3212756.
short: D.-A. Alistarh, T.A. Brown, J. Kopinsky, G. Nadiradze, in:, Proceedings of
the 2018 ACM Symposium on Principles of Distributed Computing - PODC ’18, ACM
Press, 2018, pp. 377–386.
conference:
end_date: 2018-07-27
location: Egham, United Kingdom
name: 'PODC: Principles of Distributed Computing'
start_date: 2018-07-23
date_created: 2019-02-13T10:03:25Z
date_published: 2018-07-23T00:00:00Z
date_updated: 2023-09-19T10:43:21Z
day: '23'
department:
- _id: DaAl
doi: 10.1145/3212734.3212756
external_id:
arxiv:
- '1808.04155'
isi:
- '000458186900048'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1808.04155
month: '07'
oa: 1
oa_version: Preprint
page: 377-386
publication: Proceedings of the 2018 ACM Symposium on Principles of Distributed Computing -
PODC '18
publication_identifier:
isbn:
- '9781450357951'
publication_status: published
publisher: ACM Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Relaxed schedulers can efficiently parallelize iterative algorithms
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '5965'
abstract:
- lang: eng
text: Relaxed concurrent data structures have become increasingly popular, due to
their scalability in graph processing and machine learning applications (\citeNguyen13,
gonzalez2012powergraph ). Despite considerable interest, there exist families
of natural, high performing randomized relaxed concurrent data structures, such
as the popular MultiQueue~\citeMQ pattern for implementing relaxed priority queue
data structures, for which no guarantees are known in the concurrent setting~\citeAKLN17.
Our main contribution is in showing for the first time that, under a set of analytic
assumptions, a family of relaxed concurrent data structures, including variants
of MultiQueues, but also a new approximate counting algorithm we call the MultiCounter,
provides strong probabilistic guarantees on the degree of relaxation with respect
to the sequential specification, in arbitrary concurrent executions. We formalize
these guarantees via a new correctness condition called distributional linearizability,
tailored to concurrent implementations with randomized relaxations. Our result
is based on a new analysis of an asynchronous variant of the classic power-of-two-choices
load balancing algorithm, in which placement choices can be based on inconsistent,
outdated information (this result may be of independent interest). We validate
our results empirically, showing that the MultiCounter algorithm can implement
scalable relaxed timestamps.
article_processing_charge: No
author:
- first_name: Dan-Adrian
full_name: Alistarh, Dan-Adrian
id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
last_name: Alistarh
orcid: 0000-0003-3650-940X
- first_name: Trevor A
full_name: Brown, Trevor A
id: 3569F0A0-F248-11E8-B48F-1D18A9856A87
last_name: Brown
- first_name: Justin
full_name: Kopinsky, Justin
last_name: Kopinsky
- first_name: Jerry Z.
full_name: Li, Jerry Z.
last_name: Li
- first_name: Giorgi
full_name: Nadiradze, Giorgi
last_name: Nadiradze
citation:
ama: 'Alistarh D-A, Brown TA, Kopinsky J, Li JZ, Nadiradze G. Distributionally linearizable
data structures. In: Proceedings of the 30th on Symposium on Parallelism in
Algorithms and Architectures - SPAA ’18. ACM Press; 2018:133-142. doi:10.1145/3210377.3210411'
apa: 'Alistarh, D.-A., Brown, T. A., Kopinsky, J., Li, J. Z., & Nadiradze, G.
(2018). Distributionally linearizable data structures. In Proceedings of the
30th on Symposium on Parallelism in Algorithms and Architectures - SPAA ’18
(pp. 133–142). Vienna, Austria: ACM Press. https://doi.org/10.1145/3210377.3210411'
chicago: Alistarh, Dan-Adrian, Trevor A Brown, Justin Kopinsky, Jerry Z. Li, and
Giorgi Nadiradze. “Distributionally Linearizable Data Structures.” In Proceedings
of the 30th on Symposium on Parallelism in Algorithms and Architectures - SPAA
’18, 133–42. ACM Press, 2018. https://doi.org/10.1145/3210377.3210411.
ieee: D.-A. Alistarh, T. A. Brown, J. Kopinsky, J. Z. Li, and G. Nadiradze, “Distributionally
linearizable data structures,” in Proceedings of the 30th on Symposium on Parallelism
in Algorithms and Architectures - SPAA ’18, Vienna, Austria, 2018, pp. 133–142.
ista: 'Alistarh D-A, Brown TA, Kopinsky J, Li JZ, Nadiradze G. 2018. Distributionally
linearizable data structures. Proceedings of the 30th on Symposium on Parallelism
in Algorithms and Architectures - SPAA ’18. SPAA: Symposium on Parallelism in
Algorithms and Architectures, 133–142.'
mla: Alistarh, Dan-Adrian, et al. “Distributionally Linearizable Data Structures.”
Proceedings of the 30th on Symposium on Parallelism in Algorithms and Architectures
- SPAA ’18, ACM Press, 2018, pp. 133–42, doi:10.1145/3210377.3210411.
short: D.-A. Alistarh, T.A. Brown, J. Kopinsky, J.Z. Li, G. Nadiradze, in:, Proceedings
of the 30th on Symposium on Parallelism in Algorithms and Architectures - SPAA
’18, ACM Press, 2018, pp. 133–142.
conference:
end_date: 2018-07-18
location: Vienna, Austria
name: 'SPAA: Symposium on Parallelism in Algorithms and Architectures'
start_date: 2018-07-16
date_created: 2019-02-13T10:17:19Z
date_published: 2018-07-16T00:00:00Z
date_updated: 2023-09-19T10:44:13Z
day: '16'
department:
- _id: DaAl
doi: 10.1145/3210377.3210411
external_id:
arxiv:
- '1804.01018'
isi:
- '000545269600016'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1804.01018
month: '07'
oa: 1
oa_version: Preprint
page: 133-142
publication: Proceedings of the 30th on Symposium on Parallelism in Algorithms and
Architectures - SPAA '18
publication_identifier:
isbn:
- '9781450357999'
publication_status: published
publisher: ACM Press
quality_controlled: '1'
related_material:
record:
- id: '10429'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Distributionally linearizable data structures
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '5967'
abstract:
- lang: eng
text: "The Big Match is a multi-stage two-player game. In each stage Player 1 hides
one or two pebbles in his hand, and his opponent has to guess that number; Player
1 loses a point if Player 2 is correct, and otherwise he wins a point. As soon
as Player 1 hides one pebble, the players cannot change their choices in any future
stage.\r\nBlackwell and Ferguson (1968) give an ε-optimal strategy for Player
1 that hides, in each stage, one pebble with a probability that depends on the
entire past history. Any strategy that depends just on the clock or on a finite
memory is worthless. The long-standing natural open problem has been whether every
strategy that depends just on the clock and a finite memory is worthless. We prove
that there is such a strategy that is ε-optimal. In fact, we show that just two
states of memory are sufficient.\r\n"
article_processing_charge: No
author:
- first_name: Kristoffer Arnsfelt
full_name: Hansen, Kristoffer Arnsfelt
last_name: Hansen
- first_name: Rasmus
full_name: Ibsen-Jensen, Rasmus
id: 3B699956-F248-11E8-B48F-1D18A9856A87
last_name: Ibsen-Jensen
orcid: 0000-0003-4783-0389
- first_name: Abraham
full_name: Neyman, Abraham
last_name: Neyman
citation:
ama: 'Hansen KA, Ibsen-Jensen R, Neyman A. The Big Match with a clock and a bit
of memory. In: Proceedings of the 2018 ACM Conference on Economics and Computation
- EC ’18. ACM Press; 2018:149-150. doi:10.1145/3219166.3219198'
apa: 'Hansen, K. A., Ibsen-Jensen, R., & Neyman, A. (2018). The Big Match with
a clock and a bit of memory. In Proceedings of the 2018 ACM Conference on Economics
and Computation - EC ’18 (pp. 149–150). Ithaca, NY, United States: ACM Press.
https://doi.org/10.1145/3219166.3219198'
chicago: Hansen, Kristoffer Arnsfelt, Rasmus Ibsen-Jensen, and Abraham Neyman. “The
Big Match with a Clock and a Bit of Memory.” In Proceedings of the 2018 ACM
Conference on Economics and Computation - EC ’18, 149–50. ACM Press, 2018.
https://doi.org/10.1145/3219166.3219198.
ieee: K. A. Hansen, R. Ibsen-Jensen, and A. Neyman, “The Big Match with a clock
and a bit of memory,” in Proceedings of the 2018 ACM Conference on Economics
and Computation - EC ’18, Ithaca, NY, United States, 2018, pp. 149–150.
ista: 'Hansen KA, Ibsen-Jensen R, Neyman A. 2018. The Big Match with a clock and
a bit of memory. Proceedings of the 2018 ACM Conference on Economics and Computation
- EC ’18. EC: Conference on Economics and Computation, 149–150.'
mla: Hansen, Kristoffer Arnsfelt, et al. “The Big Match with a Clock and a Bit of
Memory.” Proceedings of the 2018 ACM Conference on Economics and Computation
- EC ’18, ACM Press, 2018, pp. 149–50, doi:10.1145/3219166.3219198.
short: K.A. Hansen, R. Ibsen-Jensen, A. Neyman, in:, Proceedings of the 2018 ACM
Conference on Economics and Computation - EC ’18, ACM Press, 2018, pp. 149–150.
conference:
end_date: 2018-06-22
location: Ithaca, NY, United States
name: 'EC: Conference on Economics and Computation'
start_date: 2018-06-18
date_created: 2019-02-13T10:31:41Z
date_published: 2018-06-18T00:00:00Z
date_updated: 2023-09-19T10:45:15Z
day: '18'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1145/3219166.3219198
external_id:
isi:
- '000492755100020'
file:
- access_level: open_access
checksum: bb52683e349cfd864f4769a8f38f2798
content_type: application/pdf
creator: dernst
date_created: 2019-11-19T08:24:24Z
date_updated: 2020-07-14T12:47:14Z
file_id: '7054'
file_name: 2018_EC18_Hansen.pdf
file_size: 302539
relation: main_file
file_date_updated: 2020-07-14T12:47:14Z
has_accepted_license: '1'
isi: 1
language:
- iso: eng
month: '06'
oa: 1
oa_version: Submitted Version
page: 149-150
publication: Proceedings of the 2018 ACM Conference on Economics and Computation -
EC '18
publication_identifier:
isbn:
- '9781450358293'
publication_status: published
publisher: ACM Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: The Big Match with a clock and a bit of memory
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '5966'
abstract:
- lang: eng
text: 'The transactional conflict problem arises in transactional systems whenever
two or more concurrent transactions clash on a data item. While the standard solution
to such conflicts is to immediately abort one of the transactions, some practical
systems consider the alternative of delaying conflict resolution for a short interval,
which may allow one of the transactions to commit. The challenge in the transactional
conflict problem is to choose the optimal length of this delay interval so as
to minimize the overall running time penalty for the conflicting transactions.
In this paper, we propose a family of optimal online algorithms for the transactional
conflict problem. Specifically, we consider variants of this problem which arise
in different implementations of transactional systems, namely "requestor wins''''
and "requestor aborts'''' implementations: in the former, the recipient of a coherence
request is aborted, whereas in the latter, it is the requestor which has to abort.
Both strategies are implemented by real systems. We show that the requestor aborts
case can be reduced to a classic instance of the ski rental problem, while the
requestor wins case leads to a new version of this classical problem, for which
we derive optimal deterministic and randomized algorithms. Moreover, we prove
that, under a simplified adversarial model, our algorithms are constant-competitive
with the offline optimum in terms of throughput. We validate our algorithmic results
empirically through a hardware simulation of hardware transactional memory (HTM),
showing that our algorithms can lead to non-trivial performance improvements for
classic concurrent data structures.'
article_processing_charge: No
author:
- first_name: Dan-Adrian
full_name: Alistarh, Dan-Adrian
id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
last_name: Alistarh
orcid: 0000-0003-3650-940X
- first_name: Syed Kamran
full_name: Haider, Syed Kamran
last_name: Haider
- first_name: Raphael
full_name: Kübler, Raphael
last_name: Kübler
- first_name: Giorgi
full_name: Nadiradze, Giorgi
last_name: Nadiradze
citation:
ama: 'Alistarh D-A, Haider SK, Kübler R, Nadiradze G. The transactional conflict
problem. In: Proceedings of the 30th on Symposium on Parallelism in Algorithms
and Architectures - SPAA ’18. ACM Press; 2018:383-392. doi:10.1145/3210377.3210406'
apa: 'Alistarh, D.-A., Haider, S. K., Kübler, R., & Nadiradze, G. (2018). The
transactional conflict problem. In Proceedings of the 30th on Symposium on
Parallelism in Algorithms and Architectures - SPAA ’18 (pp. 383–392). Vienna,
Austria: ACM Press. https://doi.org/10.1145/3210377.3210406'
chicago: Alistarh, Dan-Adrian, Syed Kamran Haider, Raphael Kübler, and Giorgi Nadiradze.
“The Transactional Conflict Problem.” In Proceedings of the 30th on Symposium
on Parallelism in Algorithms and Architectures - SPAA ’18, 383–92. ACM Press,
2018. https://doi.org/10.1145/3210377.3210406.
ieee: D.-A. Alistarh, S. K. Haider, R. Kübler, and G. Nadiradze, “The transactional
conflict problem,” in Proceedings of the 30th on Symposium on Parallelism in
Algorithms and Architectures - SPAA ’18, Vienna, Austria, 2018, pp. 383–392.
ista: 'Alistarh D-A, Haider SK, Kübler R, Nadiradze G. 2018. The transactional conflict
problem. Proceedings of the 30th on Symposium on Parallelism in Algorithms and
Architectures - SPAA ’18. SPAA: Symposium on Parallelism in Algorithms and Architectures,
383–392.'
mla: Alistarh, Dan-Adrian, et al. “The Transactional Conflict Problem.” Proceedings
of the 30th on Symposium on Parallelism in Algorithms and Architectures - SPAA
’18, ACM Press, 2018, pp. 383–92, doi:10.1145/3210377.3210406.
short: D.-A. Alistarh, S.K. Haider, R. Kübler, G. Nadiradze, in:, Proceedings of
the 30th on Symposium on Parallelism in Algorithms and Architectures - SPAA ’18,
ACM Press, 2018, pp. 383–392.
conference:
end_date: 2018-07-18
location: Vienna, Austria
name: 'SPAA: Symposium on Parallelism in Algorithms and Architectures'
start_date: 2018-07-16
date_created: 2019-02-13T10:26:07Z
date_published: 2018-07-16T00:00:00Z
date_updated: 2023-09-19T10:44:49Z
day: '16'
department:
- _id: DaAl
doi: 10.1145/3210377.3210406
external_id:
arxiv:
- '1804.00947'
isi:
- '000545269600046'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1804.00947
month: '07'
oa: 1
oa_version: Preprint
page: 383-392
publication: Proceedings of the 30th on Symposium on Parallelism in Algorithms and
Architectures - SPAA '18
publication_identifier:
isbn:
- '9781450357999'
publication_status: published
publisher: ACM Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: The transactional conflict problem
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '5975'
abstract:
- lang: eng
text: We consider the recent formulation of the algorithmic Lov ́asz Local Lemma [N.
Har-vey and J. Vondr ́ak, inProceedings of FOCS, 2015, pp. 1327–1345; D. Achlioptas
and F. Iliopoulos,inProceedings of SODA, 2016, pp. 2024–2038; D. Achlioptas, F.
Iliopoulos, and V. Kolmogorov,ALocal Lemma for Focused Stochastic Algorithms,
arXiv preprint, 2018] for finding objects that avoid“bad features,” or “flaws.” It extends the Moser–Tardos resampling algorithm [R. A. Moser andG.
Tardos,J. ACM, 57 (2010), 11] to more general discrete spaces. At each step the
method picks aflaw present in the current state and goes to a new state according
to some prespecified probabilitydistribution (which depends on the current state
and the selected flaw). However, the recent formu-lation is less flexible than
the Moser–Tardos method since it requires a specific flaw selection rule,whereas
the algorithm of Moser and Tardos allows an arbitrary rule (and thus can potentially
beimplemented more efficiently). We formulate a new “commutativity” condition
and prove that it issufficient for an arbitrary rule to work. It also enables
an efficient parallelization under an additionalassumption. We then show that
existing resampling oracles for perfect matchings and permutationsdo satisfy this
condition.
article_processing_charge: No
author:
- first_name: Vladimir
full_name: Kolmogorov, Vladimir
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
citation:
ama: Kolmogorov V. Commutativity in the algorithmic Lovász local lemma. SIAM
Journal on Computing. 2018;47(6):2029-2056. doi:10.1137/16m1093306
apa: Kolmogorov, V. (2018). Commutativity in the algorithmic Lovász local lemma.
SIAM Journal on Computing. Society for Industrial & Applied Mathematics
(SIAM). https://doi.org/10.1137/16m1093306
chicago: Kolmogorov, Vladimir. “Commutativity in the Algorithmic Lovász Local Lemma.”
SIAM Journal on Computing. Society for Industrial & Applied Mathematics
(SIAM), 2018. https://doi.org/10.1137/16m1093306.
ieee: V. Kolmogorov, “Commutativity in the algorithmic Lovász local lemma,” SIAM
Journal on Computing, vol. 47, no. 6. Society for Industrial & Applied
Mathematics (SIAM), pp. 2029–2056, 2018.
ista: Kolmogorov V. 2018. Commutativity in the algorithmic Lovász local lemma. SIAM
Journal on Computing. 47(6), 2029–2056.
mla: Kolmogorov, Vladimir. “Commutativity in the Algorithmic Lovász Local Lemma.”
SIAM Journal on Computing, vol. 47, no. 6, Society for Industrial &
Applied Mathematics (SIAM), 2018, pp. 2029–56, doi:10.1137/16m1093306.
short: V. Kolmogorov, SIAM Journal on Computing 47 (2018) 2029–2056.
date_created: 2019-02-13T12:59:33Z
date_published: 2018-11-08T00:00:00Z
date_updated: 2023-09-19T14:24:58Z
day: '08'
department:
- _id: VlKo
doi: 10.1137/16m1093306
ec_funded: 1
external_id:
arxiv:
- '1506.08547'
isi:
- '000453785100001'
intvolume: ' 47'
isi: 1
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1506.08547
month: '11'
oa: 1
oa_version: Preprint
page: 2029-2056
project:
- _id: 25FBA906-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '616160'
name: 'Discrete Optimization in Computer Vision: Theory and Practice'
publication: SIAM Journal on Computing
publication_identifier:
eissn:
- 1095-7111
issn:
- 0097-5397
publication_status: published
publisher: Society for Industrial & Applied Mathematics (SIAM)
quality_controlled: '1'
related_material:
record:
- id: '1193'
relation: earlier_version
status: public
scopus_import: '1'
status: public
title: Commutativity in the algorithmic Lovász local lemma
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 47
year: '2018'
...
---
_id: '5964'
abstract:
- lang: eng
text: A standard design pattern found in many concurrent data structures, such as
hash tables or ordered containers, is an alternation of parallelizable sections
that incur no data conflicts and critical sections that must run sequentially
and are protected with locks. A lock can be viewed as a queue that arbitrates
the order in which the critical sections are executed, and a natural question
is whether we can use stochastic analysis to predict the resulting throughput.
As a preliminary evidence to the affirmative, we describe a simple model that
can be used to predict the throughput of coarse-grained lock-based algorithms.
We show that our model works well for CLH lock, and we expect it to work for other
popular lock designs such as TTAS, MCS, etc.
article_processing_charge: No
author:
- first_name: Vitaly
full_name: Aksenov, Vitaly
last_name: Aksenov
- first_name: Dan-Adrian
full_name: Alistarh, Dan-Adrian
id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
last_name: Alistarh
orcid: 0000-0003-3650-940X
- first_name: Petr
full_name: Kuznetsov, Petr
last_name: Kuznetsov
citation:
ama: 'Aksenov V, Alistarh D-A, Kuznetsov P. Brief Announcement: Performance prediction
for coarse-grained locking. In: Proceedings of the 2018 ACM Symposium on Principles
of Distributed Computing - PODC ’18. ACM Press; 2018:411-413. doi:10.1145/3212734.3212785'
apa: 'Aksenov, V., Alistarh, D.-A., & Kuznetsov, P. (2018). Brief Announcement:
Performance prediction for coarse-grained locking. In Proceedings of the 2018
ACM Symposium on Principles of Distributed Computing - PODC ’18 (pp. 411–413).
Egham, United Kingdom: ACM Press. https://doi.org/10.1145/3212734.3212785'
chicago: 'Aksenov, Vitaly, Dan-Adrian Alistarh, and Petr Kuznetsov. “Brief Announcement:
Performance Prediction for Coarse-Grained Locking.” In Proceedings of the 2018
ACM Symposium on Principles of Distributed Computing - PODC ’18, 411–13.
ACM Press, 2018. https://doi.org/10.1145/3212734.3212785.'
ieee: 'V. Aksenov, D.-A. Alistarh, and P. Kuznetsov, “Brief Announcement: Performance
prediction for coarse-grained locking,” in Proceedings of the 2018 ACM Symposium
on Principles of Distributed Computing - PODC ’18, Egham, United Kingdom,
2018, pp. 411–413.'
ista: 'Aksenov V, Alistarh D-A, Kuznetsov P. 2018. Brief Announcement: Performance
prediction for coarse-grained locking. Proceedings of the 2018 ACM Symposium on
Principles of Distributed Computing - PODC ’18. PODC: Principles of Distributed
Computing, 411–413.'
mla: 'Aksenov, Vitaly, et al. “Brief Announcement: Performance Prediction for Coarse-Grained
Locking.” Proceedings of the 2018 ACM Symposium on Principles of Distributed
Computing - PODC ’18, ACM Press, 2018, pp. 411–13, doi:10.1145/3212734.3212785.'
short: V. Aksenov, D.-A. Alistarh, P. Kuznetsov, in:, Proceedings of the 2018 ACM
Symposium on Principles of Distributed Computing - PODC ’18, ACM Press, 2018,
pp. 411–413.
conference:
end_date: 2018-07-27
location: Egham, United Kingdom
name: 'PODC: Principles of Distributed Computing'
start_date: 2018-07-23
date_created: 2019-02-13T10:08:19Z
date_published: 2018-07-23T00:00:00Z
date_updated: 2023-09-19T10:43:45Z
day: '23'
department:
- _id: DaAl
doi: 10.1145/3212734.3212785
external_id:
isi:
- '000458186900052'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://hal-univ-lyon3.archives-ouvertes.fr/INRIA/hal-01887733v1
month: '07'
oa: 1
oa_version: Submitted Version
page: 411-413
publication: Proceedings of the 2018 ACM Symposium on Principles of Distributed Computing -
PODC '18
publication_identifier:
isbn:
- '9781450357951'
publication_status: published
publisher: ACM Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Brief Announcement: Performance prediction for coarse-grained locking'
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '5971'
abstract:
- lang: eng
text: "We consider a Wigner-type ensemble, i.e. large hermitian N×N random matrices
H=H∗ with centered independent entries and with a general matrix of variances
Sxy=\U0001D53C∣∣Hxy∣∣2. The norm of H is asymptotically given by the maximum of
the support of the self-consistent density of states. We establish a bound on
this maximum in terms of norms of powers of S that substantially improves the
earlier bound 2∥S∥1/2∞ given in [O. Ajanki, L. Erdős and T. Krüger, Universality
for general Wigner-type matrices, Prob. Theor. Rel. Fields169 (2017) 667–727].
The key element of the proof is an effective Markov chain approximation for the
contributions of the weighted Dyck paths appearing in the iterative solution of
the corresponding Dyson equation."
article_number: '1950009'
article_processing_charge: No
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Peter
full_name: Mühlbacher, Peter
last_name: Mühlbacher
citation:
ama: 'Erdös L, Mühlbacher P. Bounds on the norm of Wigner-type random matrices.
Random matrices: Theory and applications. 2018. doi:10.1142/s2010326319500096'
apa: 'Erdös, L., & Mühlbacher, P. (2018). Bounds on the norm of Wigner-type
random matrices. Random Matrices: Theory and Applications. World Scientific
Publishing. https://doi.org/10.1142/s2010326319500096'
chicago: 'Erdös, László, and Peter Mühlbacher. “Bounds on the Norm of Wigner-Type
Random Matrices.” Random Matrices: Theory and Applications. World Scientific
Publishing, 2018. https://doi.org/10.1142/s2010326319500096.'
ieee: 'L. Erdös and P. Mühlbacher, “Bounds on the norm of Wigner-type random matrices,”
Random matrices: Theory and applications. World Scientific Publishing,
2018.'
ista: 'Erdös L, Mühlbacher P. 2018. Bounds on the norm of Wigner-type random matrices.
Random matrices: Theory and applications., 1950009.'
mla: 'Erdös, László, and Peter Mühlbacher. “Bounds on the Norm of Wigner-Type Random
Matrices.” Random Matrices: Theory and Applications, 1950009, World Scientific
Publishing, 2018, doi:10.1142/s2010326319500096.'
short: 'L. Erdös, P. Mühlbacher, Random Matrices: Theory and Applications (2018).'
date_created: 2019-02-13T10:40:54Z
date_published: 2018-09-26T00:00:00Z
date_updated: 2023-09-19T14:24:05Z
day: '26'
department:
- _id: LaEr
doi: 10.1142/s2010326319500096
ec_funded: 1
external_id:
arxiv:
- '1802.05175'
isi:
- '000477677200002'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1802.05175
month: '09'
oa: 1
oa_version: Preprint
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '338804'
name: Random matrices, universality and disordered quantum systems
publication: 'Random matrices: Theory and applications'
publication_identifier:
eissn:
- 2010-3271
issn:
- 2010-3263
publication_status: published
publisher: World Scientific Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Bounds on the norm of Wigner-type random matrices
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '5984'
abstract:
- lang: eng
text: G-protein-coupled receptors (GPCRs) form the largest receptor family, relay
environmental stimuli to changes in cell behavior and represent prime drug targets.
Many GPCRs are classified as orphan receptors because of the limited knowledge
on their ligands and coupling to cellular signaling machineries. Here, we engineer
a library of 63 chimeric receptors that contain the signaling domains of human
orphan and understudied GPCRs functionally linked to the light-sensing domain
of rhodopsin. Upon stimulation with visible light, we identify activation of canonical
cell signaling pathways, including cAMP-, Ca2+-, MAPK/ERK-, and Rho-dependent
pathways, downstream of the engineered receptors. For the human pseudogene GPR33,
we resurrect a signaling function that supports its hypothesized role as a pathogen
entry site. These results demonstrate that substituting unknown chemical activators
with a light switch can reveal information about protein function and provide
an optically controlled protein library for exploring the physiology and therapeutic
potential of understudied GPCRs.
article_number: '1950'
article_processing_charge: No
author:
- first_name: Maurizio
full_name: Morri, Maurizio
id: 4863116E-F248-11E8-B48F-1D18A9856A87
last_name: Morri
- first_name: Inmaculada
full_name: Sanchez-Romero, Inmaculada
id: 3D9C5D30-F248-11E8-B48F-1D18A9856A87
last_name: Sanchez-Romero
- first_name: Alexandra-Madelaine
full_name: Tichy, Alexandra-Madelaine
id: 29D8BB2C-F248-11E8-B48F-1D18A9856A87
last_name: Tichy
- first_name: Stephanie
full_name: Kainrath, Stephanie
id: 32CFBA64-F248-11E8-B48F-1D18A9856A87
last_name: Kainrath
- first_name: Elliot J.
full_name: Gerrard, Elliot J.
last_name: Gerrard
- first_name: Priscila
full_name: Hirschfeld, Priscila
id: 435ACB3A-F248-11E8-B48F-1D18A9856A87
last_name: Hirschfeld
- first_name: Jan
full_name: Schwarz, Jan
id: 346C1EC6-F248-11E8-B48F-1D18A9856A87
last_name: Schwarz
- first_name: Harald L
full_name: Janovjak, Harald L
id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
last_name: Janovjak
orcid: 0000-0002-8023-9315
citation:
ama: Morri M, Sanchez-Romero I, Tichy A-M, et al. Optical functionalization of human
class A orphan G-protein-coupled receptors. Nature Communications. 2018;9(1).
doi:10.1038/s41467-018-04342-1
apa: Morri, M., Sanchez-Romero, I., Tichy, A.-M., Kainrath, S., Gerrard, E. J.,
Hirschfeld, P., … Janovjak, H. L. (2018). Optical functionalization of human class
A orphan G-protein-coupled receptors. Nature Communications. Springer Nature.
https://doi.org/10.1038/s41467-018-04342-1
chicago: Morri, Maurizio, Inmaculada Sanchez-Romero, Alexandra-Madelaine Tichy,
Stephanie Kainrath, Elliot J. Gerrard, Priscila Hirschfeld, Jan Schwarz, and Harald
L Janovjak. “Optical Functionalization of Human Class A Orphan G-Protein-Coupled
Receptors.” Nature Communications. Springer Nature, 2018. https://doi.org/10.1038/s41467-018-04342-1.
ieee: M. Morri et al., “Optical functionalization of human class A orphan
G-protein-coupled receptors,” Nature Communications, vol. 9, no. 1. Springer
Nature, 2018.
ista: Morri M, Sanchez-Romero I, Tichy A-M, Kainrath S, Gerrard EJ, Hirschfeld P,
Schwarz J, Janovjak HL. 2018. Optical functionalization of human class A orphan
G-protein-coupled receptors. Nature Communications. 9(1), 1950.
mla: Morri, Maurizio, et al. “Optical Functionalization of Human Class A Orphan
G-Protein-Coupled Receptors.” Nature Communications, vol. 9, no. 1, 1950,
Springer Nature, 2018, doi:10.1038/s41467-018-04342-1.
short: M. Morri, I. Sanchez-Romero, A.-M. Tichy, S. Kainrath, E.J. Gerrard, P. Hirschfeld,
J. Schwarz, H.L. Janovjak, Nature Communications 9 (2018).
date_created: 2019-02-14T10:50:24Z
date_published: 2018-12-01T00:00:00Z
date_updated: 2023-09-19T14:29:32Z
day: '01'
ddc:
- '570'
department:
- _id: HaJa
- _id: CaGu
- _id: MiSi
doi: 10.1038/s41467-018-04342-1
ec_funded: 1
external_id:
isi:
- '000432280000006'
file:
- access_level: open_access
checksum: 8325fcc194264af4749e662a73bf66b5
content_type: application/pdf
creator: kschuh
date_created: 2019-02-14T10:58:29Z
date_updated: 2020-07-14T12:47:14Z
file_id: '5985'
file_name: 2018_Springer_Morri.pdf
file_size: 1349914
relation: main_file
file_date_updated: 2020-07-14T12:47:14Z
has_accepted_license: '1'
intvolume: ' 9'
isi: 1
issue: '1'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
project:
- _id: 25548C20-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '303564'
name: Microbial Ion Channels for Synthetic Neurobiology
- _id: 255A6082-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: W1232-B24
name: Molecular Drug Targets
publication: Nature Communications
publication_identifier:
issn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Optical functionalization of human class A orphan G-protein-coupled receptors
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 9
year: '2018'
...
---
_id: '5976'
abstract:
- lang: eng
text: We propose FlexMaps, a novel framework for fabricating smooth shapes out of
flat, flexible panels with tailored mechanical properties. We start by mapping
the 3D surface onto a 2D domain as in traditional UV mapping to design a set of
deformable flat panels called FlexMaps. For these panels, we design and obtain
specific mechanical properties such that, once they are assembled, the static
equilibrium configuration matches the desired 3D shape. FlexMaps can be fabricated
from an almost rigid material, such as wood or plastic, and are made flexible
in a controlled way by using computationally designed spiraling microstructures.
article_number: '241'
article_processing_charge: No
article_type: original
author:
- first_name: Luigi
full_name: Malomo, Luigi
last_name: Malomo
- first_name: Jesus
full_name: Perez Rodriguez, Jesus
id: 2DC83906-F248-11E8-B48F-1D18A9856A87
last_name: Perez Rodriguez
- first_name: Emmanuel
full_name: Iarussi, Emmanuel
id: 33F19F16-F248-11E8-B48F-1D18A9856A87
last_name: Iarussi
- first_name: Nico
full_name: Pietroni, Nico
last_name: Pietroni
- first_name: Eder
full_name: Miguel, Eder
last_name: Miguel
- first_name: Paolo
full_name: Cignoni, Paolo
last_name: Cignoni
- first_name: Bernd
full_name: Bickel, Bernd
id: 49876194-F248-11E8-B48F-1D18A9856A87
last_name: Bickel
orcid: 0000-0001-6511-9385
citation:
ama: 'Malomo L, Perez Rodriguez J, Iarussi E, et al. FlexMaps: Computational design
of flat flexible shells for shaping 3D objects. ACM Transactions on Graphics.
2018;37(6). doi:10.1145/3272127.3275076'
apa: 'Malomo, L., Perez Rodriguez, J., Iarussi, E., Pietroni, N., Miguel, E., Cignoni,
P., & Bickel, B. (2018). FlexMaps: Computational design of flat flexible shells
for shaping 3D objects. ACM Transactions on Graphics. Association for Computing
Machinery (ACM). https://doi.org/10.1145/3272127.3275076'
chicago: 'Malomo, Luigi, Jesus Perez Rodriguez, Emmanuel Iarussi, Nico Pietroni,
Eder Miguel, Paolo Cignoni, and Bernd Bickel. “FlexMaps: Computational Design
of Flat Flexible Shells for Shaping 3D Objects.” ACM Transactions on Graphics.
Association for Computing Machinery (ACM), 2018. https://doi.org/10.1145/3272127.3275076.'
ieee: 'L. Malomo et al., “FlexMaps: Computational design of flat flexible
shells for shaping 3D objects,” ACM Transactions on Graphics, vol. 37,
no. 6. Association for Computing Machinery (ACM), 2018.'
ista: 'Malomo L, Perez Rodriguez J, Iarussi E, Pietroni N, Miguel E, Cignoni P,
Bickel B. 2018. FlexMaps: Computational design of flat flexible shells for shaping
3D objects. ACM Transactions on Graphics. 37(6), 241.'
mla: 'Malomo, Luigi, et al. “FlexMaps: Computational Design of Flat Flexible Shells
for Shaping 3D Objects.” ACM Transactions on Graphics, vol. 37, no. 6,
241, Association for Computing Machinery (ACM), 2018, doi:10.1145/3272127.3275076.'
short: L. Malomo, J. Perez Rodriguez, E. Iarussi, N. Pietroni, E. Miguel, P. Cignoni,
B. Bickel, ACM Transactions on Graphics 37 (2018).
date_created: 2019-02-13T13:12:53Z
date_published: 2018-11-01T00:00:00Z
date_updated: 2023-09-19T14:25:30Z
day: '01'
ddc:
- '000'
department:
- _id: BeBi
doi: 10.1145/3272127.3275076
ec_funded: 1
external_id:
isi:
- '000455953100064'
file:
- access_level: open_access
checksum: d0529a41c78b37ab8840685579fb33b4
content_type: application/pdf
creator: bbickel
date_created: 2019-09-23T12:48:52Z
date_updated: 2020-07-14T12:47:14Z
file_id: '6901'
file_name: flexmaps_author_version.pdf
file_size: 100109811
relation: main_file
file_date_updated: 2020-07-14T12:47:14Z
has_accepted_license: '1'
intvolume: ' 37'
isi: 1
issue: '6'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
project:
- _id: 24F9549A-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '715767'
name: 'MATERIALIZABLE: Intelligent fabrication-oriented Computational Design and
Modeling'
- _id: 25082902-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '645599'
name: Soft-bodied intelligence for Manipulation
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: ACM Transactions on Graphics
publication_identifier:
issn:
- 0730-0301
publication_status: published
publisher: Association for Computing Machinery (ACM)
pubrep_id: '1068'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'FlexMaps: Computational design of flat flexible shells for shaping 3D objects'
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 37
year: '2018'
...
---
_id: '5983'
abstract:
- lang: eng
text: We study a quantum impurity possessing both translational and internal rotational
degrees of freedom interacting with a bosonic bath. Such a system corresponds
to a “rotating polaron,” which can be used to model, e.g., a rotating molecule
immersed in an ultracold Bose gas or superfluid helium. We derive the Hamiltonian
of the rotating polaron and study its spectrum in the weak- and strong-coupling
regimes using a combination of variational, diagrammatic, and mean-field approaches.
We reveal how the coupling between linear and angular momenta affects stable quasiparticle
states, and demonstrate that internal rotation leads to an enhanced self-localization
in the translational degrees of freedom.
article_number: '224506'
article_processing_charge: No
author:
- first_name: Enderalp
full_name: Yakaboylu, Enderalp
id: 38CB71F6-F248-11E8-B48F-1D18A9856A87
last_name: Yakaboylu
orcid: 0000-0001-5973-0874
- first_name: Bikashkali
full_name: Midya, Bikashkali
id: 456187FC-F248-11E8-B48F-1D18A9856A87
last_name: Midya
- first_name: Andreas
full_name: Deuchert, Andreas
id: 4DA65CD0-F248-11E8-B48F-1D18A9856A87
last_name: Deuchert
orcid: 0000-0003-3146-6746
- first_name: Nikolai K
full_name: Leopold, Nikolai K
id: 4BC40BEC-F248-11E8-B48F-1D18A9856A87
last_name: Leopold
orcid: 0000-0002-0495-6822
- first_name: Mikhail
full_name: Lemeshko, Mikhail
id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
last_name: Lemeshko
orcid: 0000-0002-6990-7802
citation:
ama: 'Yakaboylu E, Midya B, Deuchert A, Leopold NK, Lemeshko M. Theory of the rotating
polaron: Spectrum and self-localization. Physical Review B. 2018;98(22).
doi:10.1103/physrevb.98.224506'
apa: 'Yakaboylu, E., Midya, B., Deuchert, A., Leopold, N. K., & Lemeshko, M.
(2018). Theory of the rotating polaron: Spectrum and self-localization. Physical
Review B. American Physical Society. https://doi.org/10.1103/physrevb.98.224506'
chicago: 'Yakaboylu, Enderalp, Bikashkali Midya, Andreas Deuchert, Nikolai K Leopold,
and Mikhail Lemeshko. “Theory of the Rotating Polaron: Spectrum and Self-Localization.”
Physical Review B. American Physical Society, 2018. https://doi.org/10.1103/physrevb.98.224506.'
ieee: 'E. Yakaboylu, B. Midya, A. Deuchert, N. K. Leopold, and M. Lemeshko, “Theory
of the rotating polaron: Spectrum and self-localization,” Physical Review B,
vol. 98, no. 22. American Physical Society, 2018.'
ista: 'Yakaboylu E, Midya B, Deuchert A, Leopold NK, Lemeshko M. 2018. Theory of
the rotating polaron: Spectrum and self-localization. Physical Review B. 98(22),
224506.'
mla: 'Yakaboylu, Enderalp, et al. “Theory of the Rotating Polaron: Spectrum and
Self-Localization.” Physical Review B, vol. 98, no. 22, 224506, American
Physical Society, 2018, doi:10.1103/physrevb.98.224506.'
short: E. Yakaboylu, B. Midya, A. Deuchert, N.K. Leopold, M. Lemeshko, Physical
Review B 98 (2018).
date_created: 2019-02-14T10:37:09Z
date_published: 2018-12-12T00:00:00Z
date_updated: 2023-09-19T14:29:03Z
day: '12'
department:
- _id: MiLe
- _id: RoSe
doi: 10.1103/physrevb.98.224506
ec_funded: 1
external_id:
arxiv:
- '1809.01204'
isi:
- '000452992700008'
intvolume: ' 98'
isi: 1
issue: '22'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1809.01204
month: '12'
oa: 1
oa_version: Preprint
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
- _id: 25C6DC12-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '694227'
name: Analysis of quantum many-body systems
publication: Physical Review B
publication_identifier:
eissn:
- 2469-9969
issn:
- 2469-9950
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Theory of the rotating polaron: Spectrum and self-localization'
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 98
year: '2018'
...
---
_id: '5982'
abstract:
- lang: eng
text: In the present work, we detail a fast and simple solution-based method to
synthesize hexagonal SnSe2 nanoplates (NPLs) and their use to produce crystallographically
textured SnSe2 nanomaterials. We also demonstrate that the same strategy can be
used to produce orthorhombic SnSe nanostructures and nanomaterials. NPLs are grown
through a screw dislocation-driven mechanism. This mechanism typically results
in pyramidal structures, but we demonstrate here that the growth from multiple
dislocations results in flower-like structures. Crystallographically textured
SnSe2 bulk nanomaterials obtained from the hot pressing of these SnSe2 structures
display highly anisotropic charge and heat transport properties and thermoelectric
(TE) figures of merit limited by relatively low electrical conductivities. To
improve this parameter, SnSe2 NPLs are blended here with metal nanoparticles.
The electrical conductivities of the blends are significantly improved with respect
to bare SnSe2 NPLs, what translates into a three-fold increase of the TE Figure
of merit, reaching unprecedented ZT values up to 0.65.
article_processing_charge: No
article_type: original
author:
- first_name: Yu
full_name: Zhang, Yu
last_name: Zhang
- first_name: Yu
full_name: Liu, Yu
last_name: Liu
- first_name: Khak Ho
full_name: Lim, Khak Ho
last_name: Lim
- first_name: Congcong
full_name: Xing, Congcong
last_name: Xing
- first_name: Mengyao
full_name: Li, Mengyao
last_name: Li
- first_name: Ting
full_name: Zhang, Ting
last_name: Zhang
- first_name: Pengyi
full_name: Tang, Pengyi
last_name: Tang
- first_name: Jordi
full_name: Arbiol, Jordi
last_name: Arbiol
- first_name: Jordi
full_name: Llorca, Jordi
last_name: Llorca
- first_name: Ka Ming
full_name: Ng, Ka Ming
last_name: Ng
- first_name: Maria
full_name: Ibáñez, Maria
id: 43C61214-F248-11E8-B48F-1D18A9856A87
last_name: Ibáñez
orcid: 0000-0001-5013-2843
- first_name: Pablo
full_name: Guardia, Pablo
last_name: Guardia
- first_name: Mirko
full_name: Prato, Mirko
last_name: Prato
- first_name: Doris
full_name: Cadavid, Doris
last_name: Cadavid
- first_name: Andreu
full_name: Cabot, Andreu
last_name: Cabot
citation:
ama: Zhang Y, Liu Y, Lim KH, et al. Tin diselenide molecular precursor for solution-processable
thermoelectric materials. Angewandte Chemie International Edition. 2018;57(52):17063-17068.
doi:10.1002/anie.201809847
apa: Zhang, Y., Liu, Y., Lim, K. H., Xing, C., Li, M., Zhang, T., … Cabot, A. (2018).
Tin diselenide molecular precursor for solution-processable thermoelectric materials.
Angewandte Chemie International Edition. Wiley. https://doi.org/10.1002/anie.201809847
chicago: Zhang, Yu, Yu Liu, Khak Ho Lim, Congcong Xing, Mengyao Li, Ting Zhang,
Pengyi Tang, et al. “Tin Diselenide Molecular Precursor for Solution-Processable
Thermoelectric Materials.” Angewandte Chemie International Edition. Wiley,
2018. https://doi.org/10.1002/anie.201809847.
ieee: Y. Zhang et al., “Tin diselenide molecular precursor for solution-processable
thermoelectric materials,” Angewandte Chemie International Edition, vol.
57, no. 52. Wiley, pp. 17063–17068, 2018.
ista: Zhang Y, Liu Y, Lim KH, Xing C, Li M, Zhang T, Tang P, Arbiol J, Llorca J,
Ng KM, Ibáñez M, Guardia P, Prato M, Cadavid D, Cabot A. 2018. Tin diselenide
molecular precursor for solution-processable thermoelectric materials. Angewandte
Chemie International Edition. 57(52), 17063–17068.
mla: Zhang, Yu, et al. “Tin Diselenide Molecular Precursor for Solution-Processable
Thermoelectric Materials.” Angewandte Chemie International Edition, vol.
57, no. 52, Wiley, 2018, pp. 17063–68, doi:10.1002/anie.201809847.
short: Y. Zhang, Y. Liu, K.H. Lim, C. Xing, M. Li, T. Zhang, P. Tang, J. Arbiol,
J. Llorca, K.M. Ng, M. Ibáñez, P. Guardia, M. Prato, D. Cadavid, A. Cabot, Angewandte
Chemie International Edition 57 (2018) 17063–17068.
date_created: 2019-02-14T10:23:27Z
date_published: 2018-12-21T00:00:00Z
date_updated: 2023-09-19T14:28:31Z
day: '21'
department:
- _id: MaIb
doi: 10.1002/anie.201809847
external_id:
isi:
- '000454575500020'
intvolume: ' 57'
isi: 1
issue: '52'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://upcommons.upc.edu/bitstream/2117/130444/1/Zhang%20preprint.pdf
month: '12'
oa: 1
oa_version: Submitted Version
page: 17063-17068
publication: Angewandte Chemie International Edition
publication_identifier:
issn:
- 1433-7851
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Tin diselenide molecular precursor for solution-processable thermoelectric
materials
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 57
year: '2018'
...
---
_id: '5978'
abstract:
- lang: eng
text: 'We consider the MAP-inference problem for graphical models,which is a valued
constraint satisfaction problem defined onreal numbers with a natural summation
operation. We proposea family of relaxations (different from the famous Sherali-Adams
hierarchy), which naturally define lower bounds for itsoptimum. This family always
contains a tight relaxation andwe give an algorithm able to find it and therefore,
solve theinitial non-relaxed NP-hard problem.The relaxations we consider decompose
the original probleminto two non-overlapping parts: an easy LP-tight part and
adifficult one. For the latter part a combinatorial solver must beused. As we
show in our experiments, in a number of applica-tions the second, difficult part
constitutes only a small fractionof the whole problem. This property allows to
significantlyreduce the computational time of the combinatorial solver andtherefore
solve problems which were out of reach before.'
article_processing_charge: No
author:
- first_name: Stefan
full_name: Haller, Stefan
last_name: Haller
- first_name: Paul
full_name: Swoboda, Paul
id: 446560C6-F248-11E8-B48F-1D18A9856A87
last_name: Swoboda
- first_name: Bogdan
full_name: Savchynskyy, Bogdan
last_name: Savchynskyy
citation:
ama: 'Haller S, Swoboda P, Savchynskyy B. Exact MAP-inference by confining combinatorial
search with LP relaxation. In: Proceedings of the 32st AAAI Conference on Artificial
Intelligence. AAAI Press; 2018:6581-6588.'
apa: 'Haller, S., Swoboda, P., & Savchynskyy, B. (2018). Exact MAP-inference
by confining combinatorial search with LP relaxation. In Proceedings of the
32st AAAI Conference on Artificial Intelligence (pp. 6581–6588). New Orleans,
LU, United States: AAAI Press.'
chicago: Haller, Stefan, Paul Swoboda, and Bogdan Savchynskyy. “Exact MAP-Inference
by Confining Combinatorial Search with LP Relaxation.” In Proceedings of the
32st AAAI Conference on Artificial Intelligence, 6581–88. AAAI Press, 2018.
ieee: S. Haller, P. Swoboda, and B. Savchynskyy, “Exact MAP-inference by confining
combinatorial search with LP relaxation,” in Proceedings of the 32st AAAI Conference
on Artificial Intelligence, New Orleans, LU, United States, 2018, pp. 6581–6588.
ista: 'Haller S, Swoboda P, Savchynskyy B. 2018. Exact MAP-inference by confining
combinatorial search with LP relaxation. Proceedings of the 32st AAAI Conference
on Artificial Intelligence. AAAI: Conference on Artificial Intelligence, 6581–6588.'
mla: Haller, Stefan, et al. “Exact MAP-Inference by Confining Combinatorial Search
with LP Relaxation.” Proceedings of the 32st AAAI Conference on Artificial
Intelligence, AAAI Press, 2018, pp. 6581–88.
short: S. Haller, P. Swoboda, B. Savchynskyy, in:, Proceedings of the 32st AAAI
Conference on Artificial Intelligence, AAAI Press, 2018, pp. 6581–6588.
conference:
end_date: 2018-02-07
location: New Orleans, LU, United States
name: 'AAAI: Conference on Artificial Intelligence'
start_date: 2018-02-02
date_created: 2019-02-13T13:32:48Z
date_published: 2018-02-01T00:00:00Z
date_updated: 2023-09-19T14:26:52Z
day: '01'
department:
- _id: VlKo
external_id:
arxiv:
- '2004.06370'
isi:
- '000485488906082'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2004.06370
month: '02'
oa: 1
oa_version: Preprint
page: 6581-6588
publication: Proceedings of the 32st AAAI Conference on Artificial Intelligence
publication_status: published
publisher: AAAI Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Exact MAP-inference by confining combinatorial search with LP relaxation
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '5990'
abstract:
- lang: eng
text: 'A Ge–Si core–shell nanowire is used to realize a Josephson field‐effect transistor
with highly transparent contacts to superconducting leads. By changing the electric
field, access to two distinct regimes, not combined before in a single device,
is gained: in the accumulation mode the device is highly transparent and the supercurrent
is carried by multiple subbands, while near depletion, the supercurrent is carried
by single‐particle levels of a strongly coupled quantum dot operating in the few‐hole
regime. These results establish Ge–Si nanowires as an important platform for hybrid
superconductor–semiconductor physics and Majorana fermions.'
article_number: '1802257'
article_processing_charge: No
author:
- first_name: Joost
full_name: Ridderbos, Joost
last_name: Ridderbos
- first_name: Matthias
full_name: Brauns, Matthias
id: 33F94E3C-F248-11E8-B48F-1D18A9856A87
last_name: Brauns
- first_name: Jie
full_name: Shen, Jie
last_name: Shen
- first_name: Folkert K.
full_name: de Vries, Folkert K.
last_name: de Vries
- first_name: Ang
full_name: Li, Ang
last_name: Li
- first_name: Erik P. A. M.
full_name: Bakkers, Erik P. A. M.
last_name: Bakkers
- first_name: Alexander
full_name: Brinkman, Alexander
last_name: Brinkman
- first_name: Floris A.
full_name: Zwanenburg, Floris A.
last_name: Zwanenburg
citation:
ama: Ridderbos J, Brauns M, Shen J, et al. Josephson effect in a few-hole quantum
dot. Advanced Materials. 2018;30(44). doi:10.1002/adma.201802257
apa: Ridderbos, J., Brauns, M., Shen, J., de Vries, F. K., Li, A., Bakkers, E. P.
A. M., … Zwanenburg, F. A. (2018). Josephson effect in a few-hole quantum dot.
Advanced Materials. Wiley. https://doi.org/10.1002/adma.201802257
chicago: Ridderbos, Joost, Matthias Brauns, Jie Shen, Folkert K. de Vries, Ang Li,
Erik P. A. M. Bakkers, Alexander Brinkman, and Floris A. Zwanenburg. “Josephson
Effect in a Few-Hole Quantum Dot.” Advanced Materials. Wiley, 2018. https://doi.org/10.1002/adma.201802257.
ieee: J. Ridderbos et al., “Josephson effect in a few-hole quantum dot,”
Advanced Materials, vol. 30, no. 44. Wiley, 2018.
ista: Ridderbos J, Brauns M, Shen J, de Vries FK, Li A, Bakkers EPAM, Brinkman A,
Zwanenburg FA. 2018. Josephson effect in a few-hole quantum dot. Advanced Materials.
30(44), 1802257.
mla: Ridderbos, Joost, et al. “Josephson Effect in a Few-Hole Quantum Dot.” Advanced
Materials, vol. 30, no. 44, 1802257, Wiley, 2018, doi:10.1002/adma.201802257.
short: J. Ridderbos, M. Brauns, J. Shen, F.K. de Vries, A. Li, E.P.A.M. Bakkers,
A. Brinkman, F.A. Zwanenburg, Advanced Materials 30 (2018).
date_created: 2019-02-14T12:14:26Z
date_published: 2018-11-02T00:00:00Z
date_updated: 2023-09-19T14:29:58Z
day: '02'
department:
- _id: GeKa
doi: 10.1002/adma.201802257
external_id:
arxiv:
- '1809.08487'
isi:
- '000450232800015'
intvolume: ' 30'
isi: 1
issue: '44'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1809.08487
month: '11'
oa: 1
oa_version: Preprint
publication: Advanced Materials
publication_identifier:
issn:
- 0935-9648
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Josephson effect in a few-hole quantum dot
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 30
year: '2018'
...
---
_id: '5980'
abstract:
- lang: eng
text: The problem of private set-intersection (PSI) has been traditionally treated
as an instance of the more general problem of multi-party computation (MPC). Consequently,
in order to argue security, or compose these protocols one has to rely on the
general theory that was developed for the purpose of MPC. The pursuit of efficient
protocols, however, has resulted in designs that exploit properties pertaining
to PSI. In almost all practical applications where a PSI protocol is deployed,
it is expected to be executed multiple times, possibly on related inputs. In this
work we initiate a dedicated study of PSI in the multi-interaction (MI) setting.
In this model a server sets up the common system parameters and executes set-intersection
multiple times with potentially different clients. We discuss a few attacks that
arise when protocols are naïvely composed in this manner and, accordingly, craft
security definitions for the MI setting and study their inter-relation. Finally,
we suggest a set of protocols that are MI-secure, at the same time almost as efficient
as their parent, stand-alone, protocols.
article_processing_charge: No
author:
- first_name: Sanjit
full_name: Chatterjee, Sanjit
last_name: Chatterjee
- first_name: Chethan
full_name: Kamath Hosdurg, Chethan
id: 4BD3F30E-F248-11E8-B48F-1D18A9856A87
last_name: Kamath Hosdurg
- first_name: Vikas
full_name: Kumar, Vikas
last_name: Kumar
citation:
ama: Chatterjee S, Kamath Hosdurg C, Kumar V. Private set-intersection with common
set-up. American Institute of Mathematical Sciences. 2018;12(1):17-47.
doi:10.3934/amc.2018002
apa: Chatterjee, S., Kamath Hosdurg, C., & Kumar, V. (2018). Private set-intersection
with common set-up. American Institute of Mathematical Sciences. AIMS.
https://doi.org/10.3934/amc.2018002
chicago: Chatterjee, Sanjit, Chethan Kamath Hosdurg, and Vikas Kumar. “Private Set-Intersection
with Common Set-Up.” American Institute of Mathematical Sciences. AIMS,
2018. https://doi.org/10.3934/amc.2018002.
ieee: S. Chatterjee, C. Kamath Hosdurg, and V. Kumar, “Private set-intersection
with common set-up,” American Institute of Mathematical Sciences, vol.
12, no. 1. AIMS, pp. 17–47, 2018.
ista: Chatterjee S, Kamath Hosdurg C, Kumar V. 2018. Private set-intersection with
common set-up. American Institute of Mathematical Sciences. 12(1), 17–47.
mla: Chatterjee, Sanjit, et al. “Private Set-Intersection with Common Set-Up.” American
Institute of Mathematical Sciences, vol. 12, no. 1, AIMS, 2018, pp. 17–47,
doi:10.3934/amc.2018002.
short: S. Chatterjee, C. Kamath Hosdurg, V. Kumar, American Institute of Mathematical
Sciences 12 (2018) 17–47.
date_created: 2019-02-13T13:49:41Z
date_published: 2018-02-01T00:00:00Z
date_updated: 2023-09-19T14:27:59Z
day: '01'
department:
- _id: KrPi
doi: 10.3934/amc.2018002
external_id:
isi:
- '000430950400002'
intvolume: ' 12'
isi: 1
issue: '1'
language:
- iso: eng
month: '02'
oa_version: None
page: 17-47
publication: American Institute of Mathematical Sciences
publication_status: published
publisher: AIMS
quality_controlled: '1'
scopus_import: '1'
status: public
title: Private set-intersection with common set-up
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 12
year: '2018'
...
---
_id: '5998'
abstract:
- lang: eng
text: Genome amplification and cellular senescence are commonly associated with
pathological processes. While physiological roles for polyploidization and senescence
have been described in mouse development, controversy exists over their significance
in humans. Here, we describe tetraploidization and senescence as phenomena of
normal human placenta development. During pregnancy, placental extravillous trophoblasts
(EVTs) invade the pregnant endometrium, termed decidua, to establish an adapted
microenvironment required for the developing embryo. This process is critically
dependent on continuous cell proliferation and differentiation, which is thought
to follow the classical model of cell cycle arrest prior to terminal differentiation.
Strikingly, flow cytometry and DNAseq revealed that EVT formation is accompanied
with a genome-wide polyploidization, independent of mitotic cycles. DNA replication
in these cells was analysed by a fluorescent cell-cycle indicator reporter system,
cell cycle marker expression and EdU incorporation. Upon invasion into the decidua,
EVTs widely lose their replicative potential and enter a senescent state characterized
by high senescence-associated (SA) β-galactosidase activity, induction of a SA
secretory phenotype as well as typical metabolic alterations. Furthermore, we
show that the shift from endocycle-dependent genome amplification to growth arrest
is disturbed in androgenic complete hydatidiform moles (CHM), a hyperplastic pregnancy
disorder associated with increased risk of developing choriocarinoma. Senescence
is decreased in CHM-EVTs, accompanied by exacerbated endoreduplication and hyperploidy.
We propose induction of cellular senescence as a ploidy-limiting mechanism during
normal human placentation and unravel a link between excessive polyploidization
and reduced senescence in CHM.
article_number: e1007698
article_processing_charge: No
author:
- first_name: Philipp
full_name: Velicky, Philipp
id: 39BDC62C-F248-11E8-B48F-1D18A9856A87
last_name: Velicky
orcid: 0000-0002-2340-7431
- first_name: Gudrun
full_name: Meinhardt, Gudrun
last_name: Meinhardt
- first_name: Kerstin
full_name: Plessl, Kerstin
last_name: Plessl
- first_name: Sigrid
full_name: Vondra, Sigrid
last_name: Vondra
- first_name: Tamara
full_name: Weiss, Tamara
last_name: Weiss
- first_name: Peter
full_name: Haslinger, Peter
last_name: Haslinger
- first_name: Thomas
full_name: Lendl, Thomas
last_name: Lendl
- first_name: Karin
full_name: Aumayr, Karin
last_name: Aumayr
- first_name: Mario
full_name: Mairhofer, Mario
last_name: Mairhofer
- first_name: Xiaowei
full_name: Zhu, Xiaowei
last_name: Zhu
- first_name: Birgit
full_name: Schütz, Birgit
last_name: Schütz
- first_name: Roberta L.
full_name: Hannibal, Roberta L.
last_name: Hannibal
- first_name: Robert
full_name: Lindau, Robert
last_name: Lindau
- first_name: Beatrix
full_name: Weil, Beatrix
last_name: Weil
- first_name: Jan
full_name: Ernerudh, Jan
last_name: Ernerudh
- first_name: Jürgen
full_name: Neesen, Jürgen
last_name: Neesen
- first_name: Gerda
full_name: Egger, Gerda
last_name: Egger
- first_name: Mario
full_name: Mikula, Mario
last_name: Mikula
- first_name: Clemens
full_name: Röhrl, Clemens
last_name: Röhrl
- first_name: Alexander E.
full_name: Urban, Alexander E.
last_name: Urban
- first_name: Julie
full_name: Baker, Julie
last_name: Baker
- first_name: Martin
full_name: Knöfler, Martin
last_name: Knöfler
- first_name: Jürgen
full_name: Pollheimer, Jürgen
last_name: Pollheimer
citation:
ama: Velicky P, Meinhardt G, Plessl K, et al. Genome amplification and cellular
senescence are hallmarks of human placenta development. PLOS Genetics.
2018;14(10). doi:10.1371/journal.pgen.1007698
apa: Velicky, P., Meinhardt, G., Plessl, K., Vondra, S., Weiss, T., Haslinger, P.,
… Pollheimer, J. (2018). Genome amplification and cellular senescence are hallmarks
of human placenta development. PLOS Genetics. Public Library of Science.
https://doi.org/10.1371/journal.pgen.1007698
chicago: Velicky, Philipp, Gudrun Meinhardt, Kerstin Plessl, Sigrid Vondra, Tamara
Weiss, Peter Haslinger, Thomas Lendl, et al. “Genome Amplification and Cellular
Senescence Are Hallmarks of Human Placenta Development.” PLOS Genetics.
Public Library of Science, 2018. https://doi.org/10.1371/journal.pgen.1007698.
ieee: P. Velicky et al., “Genome amplification and cellular senescence are
hallmarks of human placenta development,” PLOS Genetics, vol. 14, no. 10.
Public Library of Science, 2018.
ista: Velicky P, Meinhardt G, Plessl K, Vondra S, Weiss T, Haslinger P, Lendl T,
Aumayr K, Mairhofer M, Zhu X, Schütz B, Hannibal RL, Lindau R, Weil B, Ernerudh
J, Neesen J, Egger G, Mikula M, Röhrl C, Urban AE, Baker J, Knöfler M, Pollheimer
J. 2018. Genome amplification and cellular senescence are hallmarks of human placenta
development. PLOS Genetics. 14(10), e1007698.
mla: Velicky, Philipp, et al. “Genome Amplification and Cellular Senescence Are
Hallmarks of Human Placenta Development.” PLOS Genetics, vol. 14, no. 10,
e1007698, Public Library of Science, 2018, doi:10.1371/journal.pgen.1007698.
short: P. Velicky, G. Meinhardt, K. Plessl, S. Vondra, T. Weiss, P. Haslinger, T.
Lendl, K. Aumayr, M. Mairhofer, X. Zhu, B. Schütz, R.L. Hannibal, R. Lindau, B.
Weil, J. Ernerudh, J. Neesen, G. Egger, M. Mikula, C. Röhrl, A.E. Urban, J. Baker,
M. Knöfler, J. Pollheimer, PLOS Genetics 14 (2018).
date_created: 2019-02-14T13:07:45Z
date_published: 2018-10-12T00:00:00Z
date_updated: 2023-09-19T14:31:43Z
day: '12'
ddc:
- '570'
department:
- _id: JoDa
doi: 10.1371/journal.pgen.1007698
external_id:
isi:
- '000449328500025'
file:
- access_level: open_access
checksum: 34aa9a5972f61889c19f18be8ee787a0
content_type: application/pdf
creator: kschuh
date_created: 2019-02-14T13:14:35Z
date_updated: 2020-07-14T12:47:15Z
file_id: '6000'
file_name: 2018_PLOS_Velicky.pdf
file_size: 4592947
relation: main_file
file_date_updated: 2020-07-14T12:47:15Z
has_accepted_license: '1'
intvolume: ' 14'
isi: 1
issue: '10'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
publication: PLOS Genetics
publication_identifier:
issn:
- 1553-7404
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Genome amplification and cellular senescence are hallmarks of human placenta
development
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 14
year: '2018'
...
---
_id: '5995'
abstract:
- lang: eng
text: "Motivation\r\nComputational prediction of the effect of mutations on protein
stability is used by researchers in many fields. The utility of the prediction
methods is affected by their accuracy and bias. Bias, a systematic shift of the
predicted change of stability, has been noted as an issue for several methods,
but has not been investigated systematically. Presence of the bias may lead to
misleading results especially when exploring the effects of combination of different
mutations.\r\n\r\nResults\r\nHere we use a protocol to measure the bias as a function
of the number of introduced mutations. It is based on a self-consistency test
of the reciprocity the effect of a mutation. An advantage of the used approach
is that it relies solely on crystal structures without experimentally measured
stability values. We applied the protocol to four popular algorithms predicting
change of protein stability upon mutation, FoldX, Eris, Rosetta and I-Mutant,
and found an inherent bias. For one program, FoldX, we manage to substantially
reduce the bias using additional relaxation by Modeller. Authors using algorithms
for predicting effects of mutations should be aware of the bias described here."
article_processing_charge: No
author:
- first_name: Dinara R
full_name: Usmanova, Dinara R
last_name: Usmanova
- first_name: Natalya S
full_name: Bogatyreva, Natalya S
last_name: Bogatyreva
- first_name: Joan
full_name: Ariño Bernad, Joan
last_name: Ariño Bernad
- first_name: Aleksandra A
full_name: Eremina, Aleksandra A
last_name: Eremina
- first_name: Anastasiya A
full_name: Gorshkova, Anastasiya A
last_name: Gorshkova
- first_name: German M
full_name: Kanevskiy, German M
last_name: Kanevskiy
- first_name: Lyubov R
full_name: Lonishin, Lyubov R
last_name: Lonishin
- first_name: Alexander V
full_name: Meister, Alexander V
last_name: Meister
- first_name: Alisa G
full_name: Yakupova, Alisa G
last_name: Yakupova
- first_name: Fyodor
full_name: Kondrashov, Fyodor
id: 44FDEF62-F248-11E8-B48F-1D18A9856A87
last_name: Kondrashov
orcid: 0000-0001-8243-4694
- first_name: Dmitry
full_name: Ivankov, Dmitry
id: 49FF1036-F248-11E8-B48F-1D18A9856A87
last_name: Ivankov
citation:
ama: Usmanova DR, Bogatyreva NS, Ariño Bernad J, et al. Self-consistency test reveals
systematic bias in programs for prediction change of stability upon mutation.
Bioinformatics. 2018;34(21):3653-3658. doi:10.1093/bioinformatics/bty340
apa: Usmanova, D. R., Bogatyreva, N. S., Ariño Bernad, J., Eremina, A. A., Gorshkova,
A. A., Kanevskiy, G. M., … Ivankov, D. (2018). Self-consistency test reveals systematic
bias in programs for prediction change of stability upon mutation. Bioinformatics.
Oxford University Press . https://doi.org/10.1093/bioinformatics/bty340
chicago: Usmanova, Dinara R, Natalya S Bogatyreva, Joan Ariño Bernad, Aleksandra
A Eremina, Anastasiya A Gorshkova, German M Kanevskiy, Lyubov R Lonishin, et al.
“Self-Consistency Test Reveals Systematic Bias in Programs for Prediction Change
of Stability upon Mutation.” Bioinformatics. Oxford University Press ,
2018. https://doi.org/10.1093/bioinformatics/bty340.
ieee: D. R. Usmanova et al., “Self-consistency test reveals systematic bias
in programs for prediction change of stability upon mutation,” Bioinformatics,
vol. 34, no. 21. Oxford University Press , pp. 3653–3658, 2018.
ista: Usmanova DR, Bogatyreva NS, Ariño Bernad J, Eremina AA, Gorshkova AA, Kanevskiy
GM, Lonishin LR, Meister AV, Yakupova AG, Kondrashov F, Ivankov D. 2018. Self-consistency
test reveals systematic bias in programs for prediction change of stability upon
mutation. Bioinformatics. 34(21), 3653–3658.
mla: Usmanova, Dinara R., et al. “Self-Consistency Test Reveals Systematic Bias
in Programs for Prediction Change of Stability upon Mutation.” Bioinformatics,
vol. 34, no. 21, Oxford University Press , 2018, pp. 3653–58, doi:10.1093/bioinformatics/bty340.
short: D.R. Usmanova, N.S. Bogatyreva, J. Ariño Bernad, A.A. Eremina, A.A. Gorshkova,
G.M. Kanevskiy, L.R. Lonishin, A.V. Meister, A.G. Yakupova, F. Kondrashov, D.
Ivankov, Bioinformatics 34 (2018) 3653–3658.
date_created: 2019-02-14T12:48:00Z
date_published: 2018-11-01T00:00:00Z
date_updated: 2023-09-19T14:31:13Z
day: '01'
ddc:
- '570'
department:
- _id: FyKo
doi: 10.1093/bioinformatics/bty340
ec_funded: 1
external_id:
isi:
- '000450038900008'
pmid:
- '29722803'
file:
- access_level: open_access
checksum: 7e0495153f44211479674601d7f6ee03
content_type: application/pdf
creator: kschuh
date_created: 2019-02-14T13:00:55Z
date_updated: 2020-07-14T12:47:15Z
file_id: '5997'
file_name: 2018_Oxford_Usmanova.pdf
file_size: 291969
relation: main_file
file_date_updated: 2020-07-14T12:47:15Z
has_accepted_license: '1'
intvolume: ' 34'
isi: 1
issue: '21'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: 3653-3658
pmid: 1
project:
- _id: 26120F5C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '335980'
name: Systematic investigation of epistasis in molecular evolution
publication: Bioinformatics
publication_identifier:
issn:
- 1367-4803
- 1460-2059
publication_status: published
publisher: 'Oxford University Press '
quality_controlled: '1'
scopus_import: '1'
status: public
title: Self-consistency test reveals systematic bias in programs for prediction change
of stability upon mutation
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 34
year: '2018'
...
---
_id: '5992'
abstract:
- lang: eng
text: Lamellipodia are flat membrane protrusions formed during mesenchymal motion.
Polymerization at the leading edge assembles the actin filament network and generates
protrusion force. How this force is supported by the network and how the assembly
rate is shared between protrusion and network retrograde flow determines the protrusion
rate. We use mathematical modeling to understand experiments changing the F-actin
density in lamellipodia of B16-F1 melanoma cells by modulation of Arp2/3 complex
activity or knockout of the formins FMNL2 and FMNL3. Cells respond to a reduction
of density with a decrease of protrusion velocity, an increase in the ratio of
force to filament number, but constant network assembly rate. The relation between
protrusion force and tension gradient in the F-actin network and the density dependency
of friction, elasticity, and viscosity of the network explain the experimental
observations. The formins act as filament nucleators and elongators with differential
rates. Modulation of their activity suggests an effect on network assembly rate.
Contrary to these expectations, the effect of changes in elongator composition
is much weaker than the consequences of the density change. We conclude that the
force acting on the leading edge membrane is the force required to drive F-actin
network retrograde flow.
article_processing_charge: No
author:
- first_name: Setareh
full_name: Dolati, Setareh
last_name: Dolati
- first_name: Frieda
full_name: Kage, Frieda
last_name: Kage
- first_name: Jan
full_name: Mueller, Jan
last_name: Mueller
- first_name: Mathias
full_name: Müsken, Mathias
last_name: Müsken
- first_name: Marieluise
full_name: Kirchner, Marieluise
last_name: Kirchner
- first_name: Gunnar
full_name: Dittmar, Gunnar
last_name: Dittmar
- first_name: Michael K
full_name: Sixt, Michael K
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
- first_name: Klemens
full_name: Rottner, Klemens
last_name: Rottner
- first_name: Martin
full_name: Falcke, Martin
last_name: Falcke
citation:
ama: Dolati S, Kage F, Mueller J, et al. On the relation between filament density,
force generation, and protrusion rate in mesenchymal cell motility. Molecular
Biology of the Cell. 2018;29(22):2674-2686. doi:10.1091/mbc.e18-02-0082
apa: Dolati, S., Kage, F., Mueller, J., Müsken, M., Kirchner, M., Dittmar, G., …
Falcke, M. (2018). On the relation between filament density, force generation,
and protrusion rate in mesenchymal cell motility. Molecular Biology of the
Cell. American Society for Cell Biology . https://doi.org/10.1091/mbc.e18-02-0082
chicago: Dolati, Setareh, Frieda Kage, Jan Mueller, Mathias Müsken, Marieluise Kirchner,
Gunnar Dittmar, Michael K Sixt, Klemens Rottner, and Martin Falcke. “On the Relation
between Filament Density, Force Generation, and Protrusion Rate in Mesenchymal
Cell Motility.” Molecular Biology of the Cell. American Society for Cell
Biology , 2018. https://doi.org/10.1091/mbc.e18-02-0082.
ieee: S. Dolati et al., “On the relation between filament density, force
generation, and protrusion rate in mesenchymal cell motility,” Molecular Biology
of the Cell, vol. 29, no. 22. American Society for Cell Biology , pp. 2674–2686,
2018.
ista: Dolati S, Kage F, Mueller J, Müsken M, Kirchner M, Dittmar G, Sixt MK, Rottner
K, Falcke M. 2018. On the relation between filament density, force generation,
and protrusion rate in mesenchymal cell motility. Molecular Biology of the Cell.
29(22), 2674–2686.
mla: Dolati, Setareh, et al. “On the Relation between Filament Density, Force Generation,
and Protrusion Rate in Mesenchymal Cell Motility.” Molecular Biology of the
Cell, vol. 29, no. 22, American Society for Cell Biology , 2018, pp. 2674–86,
doi:10.1091/mbc.e18-02-0082.
short: S. Dolati, F. Kage, J. Mueller, M. Müsken, M. Kirchner, G. Dittmar, M.K.
Sixt, K. Rottner, M. Falcke, Molecular Biology of the Cell 29 (2018) 2674–2686.
date_created: 2019-02-14T12:25:47Z
date_published: 2018-11-01T00:00:00Z
date_updated: 2023-09-19T14:30:23Z
day: '01'
ddc:
- '570'
department:
- _id: MiSi
doi: 10.1091/mbc.e18-02-0082
external_id:
isi:
- '000455641000011'
pmid:
- '30156465'
file:
- access_level: open_access
checksum: e98465b4416b3e804c47f40086932af2
content_type: application/pdf
creator: kschuh
date_created: 2019-02-14T12:34:29Z
date_updated: 2020-07-14T12:47:15Z
file_id: '5994'
file_name: 2018_ASCB_Dolati.pdf
file_size: 6668971
relation: main_file
file_date_updated: 2020-07-14T12:47:15Z
has_accepted_license: '1'
intvolume: ' 29'
isi: 1
issue: '22'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-sa/4.0/
month: '11'
oa: 1
oa_version: Published Version
page: 2674-2686
pmid: 1
publication: Molecular Biology of the Cell
publication_identifier:
eissn:
- 1939-4586
publication_status: published
publisher: 'American Society for Cell Biology '
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the relation between filament density, force generation, and protrusion
rate in mesenchymal cell motility
tmp:
image: /images/cc_by_nc_sa.png
legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
BY-NC-SA 4.0)
short: CC BY-NC-SA (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 29
year: '2018'
...
---
_id: '6010'
abstract:
- lang: eng
text: The optic tectum (TeO), or superior colliculus, is a multisensory midbrain
center that organizes spatially orienting responses to relevant stimuli. To define
the stimulus with the highest priority at each moment, a network of reciprocal
connections between the TeO and the isthmi promotes competition between concurrent
tectal inputs. In the avian midbrain, the neurons mediating enhancement and suppression
of tectal inputs are located in separate isthmic nuclei, facilitating the analysis
of the neural processes that mediate competition. A specific subset of radial
neurons in the intermediate tectal layers relay retinal inputs to the isthmi,
but at present it is unclear whether separate neurons innervate individual nuclei
or a single neural type sends a common input to several of them. In this study,
we used in vitro neural tracing and cell-filling experiments in chickens to show
that single neurons innervate, via axon collaterals, the three nuclei that comprise
the isthmotectal network. This demonstrates that the input signals representing
the strength of the incoming stimuli are simultaneously relayed to the mechanisms
promoting both enhancement and suppression of the input signals. By performing
in vivo recordings in anesthetized chicks, we also show that this common input
generates synchrony between both antagonistic mechanisms, demonstrating that activity
enhancement and suppression are closely coordinated. From a computational point
of view, these results suggest that these tectal neurons constitute integrative
nodes that combine inputs from different sources to drive in parallel several
concurrent neural processes, each performing complementary functions within the
network through different firing patterns and connectivity.
article_processing_charge: No
author:
- first_name: Florencia
full_name: Garrido-Charad, Florencia
last_name: Garrido-Charad
- first_name: Tomas A
full_name: Vega Zuniga, Tomas A
id: 2E7C4E78-F248-11E8-B48F-1D18A9856A87
last_name: Vega Zuniga
- first_name: Cristián
full_name: Gutiérrez-Ibáñez, Cristián
last_name: Gutiérrez-Ibáñez
- first_name: Pedro
full_name: Fernandez, Pedro
last_name: Fernandez
- first_name: Luciana
full_name: López-Jury, Luciana
last_name: López-Jury
- first_name: Cristian
full_name: González-Cabrera, Cristian
last_name: González-Cabrera
- first_name: Harvey J.
full_name: Karten, Harvey J.
last_name: Karten
- first_name: Harald
full_name: Luksch, Harald
last_name: Luksch
- first_name: Gonzalo J.
full_name: Marín, Gonzalo J.
last_name: Marín
citation:
ama: Garrido-Charad F, Vega Zuniga TA, Gutiérrez-Ibáñez C, et al. “Shepherd’s crook”
neurons drive and synchronize the enhancing and suppressive mechanisms of the
midbrain stimulus selection network. Proceedings of the National Academy of
Sciences. 2018;115(32):E7615-E7623. doi:10.1073/pnas.1804517115
apa: Garrido-Charad, F., Vega Zuniga, T. A., Gutiérrez-Ibáñez, C., Fernandez, P.,
López-Jury, L., González-Cabrera, C., … Marín, G. J. (2018). “Shepherd’s crook”
neurons drive and synchronize the enhancing and suppressive mechanisms of the
midbrain stimulus selection network. Proceedings of the National Academy of
Sciences. National Academy of Sciences. https://doi.org/10.1073/pnas.1804517115
chicago: Garrido-Charad, Florencia, Tomas A Vega Zuniga, Cristián Gutiérrez-Ibáñez,
Pedro Fernandez, Luciana López-Jury, Cristian González-Cabrera, Harvey J. Karten,
Harald Luksch, and Gonzalo J. Marín. ““Shepherd’s Crook” Neurons Drive and Synchronize
the Enhancing and Suppressive Mechanisms of the Midbrain Stimulus Selection Network.”
Proceedings of the National Academy of Sciences. National Academy of Sciences,
2018. https://doi.org/10.1073/pnas.1804517115.
ieee: F. Garrido-Charad et al., ““Shepherd’s crook” neurons drive and synchronize
the enhancing and suppressive mechanisms of the midbrain stimulus selection network,”
Proceedings of the National Academy of Sciences, vol. 115, no. 32. National
Academy of Sciences, pp. E7615–E7623, 2018.
ista: Garrido-Charad F, Vega Zuniga TA, Gutiérrez-Ibáñez C, Fernandez P, López-Jury
L, González-Cabrera C, Karten HJ, Luksch H, Marín GJ. 2018. “Shepherd’s crook”
neurons drive and synchronize the enhancing and suppressive mechanisms of the
midbrain stimulus selection network. Proceedings of the National Academy of Sciences.
115(32), E7615–E7623.
mla: Garrido-Charad, Florencia, et al. ““Shepherd’s Crook” Neurons Drive and Synchronize
the Enhancing and Suppressive Mechanisms of the Midbrain Stimulus Selection Network.”
Proceedings of the National Academy of Sciences, vol. 115, no. 32, National
Academy of Sciences, 2018, pp. E7615–23, doi:10.1073/pnas.1804517115.
short: F. Garrido-Charad, T.A. Vega Zuniga, C. Gutiérrez-Ibáñez, P. Fernandez, L.
López-Jury, C. González-Cabrera, H.J. Karten, H. Luksch, G.J. Marín, Proceedings
of the National Academy of Sciences 115 (2018) E7615–E7623.
date_created: 2019-02-14T14:33:34Z
date_published: 2018-08-07T00:00:00Z
date_updated: 2023-09-19T14:35:36Z
day: '07'
department:
- _id: MaJö
doi: 10.1073/pnas.1804517115
external_id:
isi:
- '000440982000020'
pmid:
- '30026198'
intvolume: ' 115'
isi: 1
issue: '32'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pubmed/30026198
month: '08'
oa: 1
oa_version: Submitted Version
page: E7615-E7623
pmid: 1
publication: Proceedings of the National Academy of Sciences
publication_identifier:
eissn:
- 1091-6490
issn:
- 0027-8424
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: “Shepherd’s crook” neurons drive and synchronize the enhancing and suppressive
mechanisms of the midbrain stimulus selection network
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 115
year: '2018'
...
---
_id: '6003'
abstract:
- lang: eng
text: Digital fabrication devices are powerful tools for creating tangible reproductions
of 3D digital models. Most available printing technologies aim at producing an
accurate copy of a tridimensional shape. However, fabrication technologies can
also be used to create a stylistic representation of a digital shape. We refer
to this class of methods as ‘stylized fabrication methods’. These methods abstract
geometric and physical features of a given shape to create an unconventional representation,
to produce an optical illusion or to devise a particular interaction with the
fabricated model. In this state‐of‐the‐art report, we classify and overview this
broad and emerging class of approaches and also propose possible directions for
future research.
article_processing_charge: No
author:
- first_name: Bernd
full_name: Bickel, Bernd
id: 49876194-F248-11E8-B48F-1D18A9856A87
last_name: Bickel
orcid: 0000-0001-6511-9385
- first_name: Paolo
full_name: Cignoni, Paolo
last_name: Cignoni
- first_name: Luigi
full_name: Malomo, Luigi
last_name: Malomo
- first_name: Nico
full_name: Pietroni, Nico
last_name: Pietroni
citation:
ama: Bickel B, Cignoni P, Malomo L, Pietroni N. State of the art on stylized fabrication.
Computer Graphics Forum. 2018;37(6):325-342. doi:10.1111/cgf.13327
apa: Bickel, B., Cignoni, P., Malomo, L., & Pietroni, N. (2018). State of the
art on stylized fabrication. Computer Graphics Forum. Wiley. https://doi.org/10.1111/cgf.13327
chicago: Bickel, Bernd, Paolo Cignoni, Luigi Malomo, and Nico Pietroni. “State of
the Art on Stylized Fabrication.” Computer Graphics Forum. Wiley, 2018.
https://doi.org/10.1111/cgf.13327.
ieee: B. Bickel, P. Cignoni, L. Malomo, and N. Pietroni, “State of the art on stylized
fabrication,” Computer Graphics Forum, vol. 37, no. 6. Wiley, pp. 325–342,
2018.
ista: Bickel B, Cignoni P, Malomo L, Pietroni N. 2018. State of the art on stylized
fabrication. Computer Graphics Forum. 37(6), 325–342.
mla: Bickel, Bernd, et al. “State of the Art on Stylized Fabrication.” Computer
Graphics Forum, vol. 37, no. 6, Wiley, 2018, pp. 325–42, doi:10.1111/cgf.13327.
short: B. Bickel, P. Cignoni, L. Malomo, N. Pietroni, Computer Graphics Forum 37
(2018) 325–342.
date_created: 2019-02-14T13:52:25Z
date_published: 2018-09-01T00:00:00Z
date_updated: 2023-09-19T14:33:40Z
day: '01'
ddc:
- '004'
department:
- _id: BeBi
doi: 10.1111/cgf.13327
ec_funded: 1
external_id:
isi:
- '000437272800019'
file:
- access_level: open_access
checksum: d2bbe5c658d8159fbe9016a4f5e82b19
content_type: application/pdf
creator: kschuh
date_created: 2019-02-14T14:09:28Z
date_updated: 2020-07-14T12:47:15Z
file_id: '6004'
file_name: StylizedFabricationSTAR-Personal.pdf
file_size: 6209349
relation: main_file
file_date_updated: 2020-07-14T12:47:15Z
has_accepted_license: '1'
intvolume: ' 37'
isi: 1
issue: '6'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Submitted Version
page: 325-342
project:
- _id: 24F9549A-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '715767'
name: 'MATERIALIZABLE: Intelligent fabrication-oriented Computational Design and
Modeling'
publication: Computer Graphics Forum
publication_identifier:
issn:
- 0167-7055
publication_status: published
publisher: Wiley
pubrep_id: '1051'
quality_controlled: '1'
scopus_import: '1'
status: public
title: State of the art on stylized fabrication
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 37
year: '2018'
...
---
_id: '6002'
abstract:
- lang: eng
text: The Bogoliubov free energy functional is analysed. The functional serves as
a model of a translation-invariant Bose gas at positive temperature. We prove
the existence of minimizers in the case of repulsive interactions given by a sufficiently
regular two-body potential. Furthermore, we prove the existence of a phase transition
in this model and provide its phase diagram.
article_processing_charge: No
author:
- first_name: Marcin M
full_name: Napiórkowski, Marcin M
id: 4197AD04-F248-11E8-B48F-1D18A9856A87
last_name: Napiórkowski
- first_name: Robin
full_name: Reuvers, Robin
last_name: Reuvers
- first_name: Jan Philip
full_name: Solovej, Jan Philip
last_name: Solovej
citation:
ama: 'Napiórkowski MM, Reuvers R, Solovej JP. The Bogoliubov free energy functional
I: Existence of minimizers and phase diagram. Archive for Rational Mechanics
and Analysis. 2018;229(3):1037-1090. doi:10.1007/s00205-018-1232-6'
apa: 'Napiórkowski, M. M., Reuvers, R., & Solovej, J. P. (2018). The Bogoliubov
free energy functional I: Existence of minimizers and phase diagram. Archive
for Rational Mechanics and Analysis. Springer Nature. https://doi.org/10.1007/s00205-018-1232-6'
chicago: 'Napiórkowski, Marcin M, Robin Reuvers, and Jan Philip Solovej. “The Bogoliubov
Free Energy Functional I: Existence of Minimizers and Phase Diagram.” Archive
for Rational Mechanics and Analysis. Springer Nature, 2018. https://doi.org/10.1007/s00205-018-1232-6.'
ieee: 'M. M. Napiórkowski, R. Reuvers, and J. P. Solovej, “The Bogoliubov free energy
functional I: Existence of minimizers and phase diagram,” Archive for Rational
Mechanics and Analysis, vol. 229, no. 3. Springer Nature, pp. 1037–1090, 2018.'
ista: 'Napiórkowski MM, Reuvers R, Solovej JP. 2018. The Bogoliubov free energy
functional I: Existence of minimizers and phase diagram. Archive for Rational
Mechanics and Analysis. 229(3), 1037–1090.'
mla: 'Napiórkowski, Marcin M., et al. “The Bogoliubov Free Energy Functional I:
Existence of Minimizers and Phase Diagram.” Archive for Rational Mechanics
and Analysis, vol. 229, no. 3, Springer Nature, 2018, pp. 1037–90, doi:10.1007/s00205-018-1232-6.'
short: M.M. Napiórkowski, R. Reuvers, J.P. Solovej, Archive for Rational Mechanics
and Analysis 229 (2018) 1037–1090.
date_created: 2019-02-14T13:40:53Z
date_published: 2018-09-01T00:00:00Z
date_updated: 2023-09-19T14:33:12Z
day: '01'
department:
- _id: RoSe
doi: 10.1007/s00205-018-1232-6
external_id:
arxiv:
- '1511.05935'
isi:
- '000435367300003'
intvolume: ' 229'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1511.05935
month: '09'
oa: 1
oa_version: Preprint
page: 1037-1090
project:
- _id: 25C878CE-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P27533_N27
name: Structure of the Excitation Spectrum for Many-Body Quantum Systems
publication: Archive for Rational Mechanics and Analysis
publication_identifier:
eissn:
- 1432-0673
issn:
- 0003-9527
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The Bogoliubov free energy functional I: Existence of minimizers and phase
diagram'
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 229
year: '2018'
...
---
_id: '5996'
abstract:
- lang: eng
text: 'In pipes, turbulence sets in despite the linear stability of the laminar
Hagen–Poiseuille flow. The Reynolds number ( ) for which turbulence first appears
in a given experiment – the ‘natural transition point’ – depends on imperfections
of the set-up, or, more precisely, on the magnitude of finite amplitude perturbations.
At onset, turbulence typically only occupies a certain fraction of the flow, and
this fraction equally is found to differ from experiment to experiment. Despite
these findings, Reynolds proposed that after sufficiently long times, flows may
settle to steady conditions: below a critical velocity, flows should (regardless
of initial conditions) always return to laminar, while above this velocity, eddying
motion should persist. As will be shown, even in pipes several thousand diameters
long, the spatio-temporal intermittent flow patterns observed at the end of the
pipe strongly depend on the initial conditions, and there is no indication that
different flow patterns would eventually settle to a (statistical) steady state.
Exploiting the fact that turbulent puffs do not age (i.e. they are memoryless),
we continuously recreate the puff sequence exiting the pipe at the pipe entrance,
and in doing so introduce periodic boundary conditions for the puff pattern. This
procedure allows us to study the evolution of the flow patterns for arbitrary
long times, and we find that after times in excess of advective time units, indeed
a statistical steady state is reached. Although the resulting flows remain spatio-temporally
intermittent, puff splitting and decay rates eventually reach a balance, so that
the turbulent fraction fluctuates around a well-defined level which only depends
on . In accordance with Reynolds’ proposition, we find that at lower (here 2020),
flows eventually always resume to laminar, while for higher ( ), turbulence persists.
The critical point for pipe flow hence falls in the interval of $2020 , which
is in very good agreement with the recently proposed value of . The latter estimate
was based on single-puff statistics and entirely neglected puff interactions.
Unlike in typical contact processes where such interactions strongly affect the
percolation threshold, in pipe flow, the critical point is only marginally influenced.
Interactions, on the other hand, are responsible for the approach to the statistical
steady state. As shown, they strongly affect the resulting flow patterns, where
they cause ‘puff clustering’, and these regions of large puff densities are observed
to travel across the puff pattern in a wave-like fashion.'
acknowledgement: ' We also thank Philipp Maier and the IST Austria workshop for theirdedicated
technical support'
article_processing_charge: No
article_type: original
author:
- first_name: Mukund
full_name: Vasudevan, Mukund
id: 3C5A959A-F248-11E8-B48F-1D18A9856A87
last_name: Vasudevan
- first_name: Björn
full_name: Hof, Björn
id: 3A374330-F248-11E8-B48F-1D18A9856A87
last_name: Hof
orcid: 0000-0003-2057-2754
citation:
ama: Vasudevan M, Hof B. The critical point of the transition to turbulence in pipe
flow. Journal of Fluid Mechanics. 2018;839:76-94. doi:10.1017/jfm.2017.923
apa: Vasudevan, M., & Hof, B. (2018). The critical point of the transition to
turbulence in pipe flow. Journal of Fluid Mechanics. Cambridge University
Press. https://doi.org/10.1017/jfm.2017.923
chicago: Vasudevan, Mukund, and Björn Hof. “The Critical Point of the Transition
to Turbulence in Pipe Flow.” Journal of Fluid Mechanics. Cambridge University
Press, 2018. https://doi.org/10.1017/jfm.2017.923.
ieee: M. Vasudevan and B. Hof, “The critical point of the transition to turbulence
in pipe flow,” Journal of Fluid Mechanics, vol. 839. Cambridge University
Press, pp. 76–94, 2018.
ista: Vasudevan M, Hof B. 2018. The critical point of the transition to turbulence
in pipe flow. Journal of Fluid Mechanics. 839, 76–94.
mla: Vasudevan, Mukund, and Björn Hof. “The Critical Point of the Transition to
Turbulence in Pipe Flow.” Journal of Fluid Mechanics, vol. 839, Cambridge
University Press, 2018, pp. 76–94, doi:10.1017/jfm.2017.923.
short: M. Vasudevan, B. Hof, Journal of Fluid Mechanics 839 (2018) 76–94.
date_created: 2019-02-14T12:50:50Z
date_published: 2018-03-25T00:00:00Z
date_updated: 2023-09-19T14:37:49Z
day: '25'
department:
- _id: BjHo
doi: 10.1017/jfm.2017.923
ec_funded: 1
external_id:
arxiv:
- '1709.06372'
isi:
- '000437858300003'
intvolume: ' 839'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1709.06372
month: '03'
oa: 1
oa_version: Preprint
page: 76-94
project:
- _id: 25152F3A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '306589'
name: Decoding the complexity of turbulence at its origin
publication: Journal of Fluid Mechanics
publication_identifier:
eissn:
- 1469-7645
issn:
- 0022-1120
publication_status: published
publisher: Cambridge University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: The critical point of the transition to turbulence in pipe flow
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 839
year: '2018'
...
---
_id: '5993'
abstract:
- lang: eng
text: 'In this article, we consider the termination problem of probabilistic programs
with real-valued variables. Thequestions concerned are: qualitative ones that
ask (i) whether the program terminates with probability 1(almost-sure termination)
and (ii) whether the expected termination time is finite (finite termination);
andquantitative ones that ask (i) to approximate the expected termination time
(expectation problem) and (ii) tocompute a boundBsuch that the probability not
to terminate afterBsteps decreases exponentially (con-centration problem). To
solve these questions, we utilize the notion of ranking supermartingales, which
isa powerful approach for proving termination of probabilistic programs. In detail,
we focus on algorithmicsynthesis of linear ranking-supermartingales over affine
probabilistic programs (Apps) with both angelic anddemonic non-determinism. An
important subclass of Apps is LRApp which is defined as the class of all Appsover
which a linear ranking-supermartingale exists.Our main contributions are as follows.
Firstly, we show that the membership problem of LRApp (i) canbe decided in polynomial
time for Apps with at most demonic non-determinism, and (ii) isNP-hard and inPSPACEfor
Apps with angelic non-determinism. Moreover, theNP-hardness result holds already
for Appswithout probability and demonic non-determinism. Secondly, we show that
the concentration problem overLRApp can be solved in the same complexity as for
the membership problem of LRApp. Finally, we show thatthe expectation problem
over LRApp can be solved in2EXPTIMEand isPSPACE-hard even for Apps withoutprobability
and non-determinism (i.e., deterministic programs). Our experimental results demonstrate
theeffectiveness of our approach to answer the qualitative and quantitative questions
over Apps with at mostdemonic non-determinism.'
article_number: '7'
article_processing_charge: No
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Hongfei
full_name: Fu, Hongfei
id: 3AAD03D6-F248-11E8-B48F-1D18A9856A87
last_name: Fu
- first_name: Petr
full_name: Novotný, Petr
id: 3CC3B868-F248-11E8-B48F-1D18A9856A87
last_name: Novotný
- first_name: Rouzbeh
full_name: Hasheminezhad, Rouzbeh
last_name: Hasheminezhad
citation:
ama: Chatterjee K, Fu H, Novotný P, Hasheminezhad R. Algorithmic analysis of qualitative
and quantitative termination problems for affine probabilistic programs. ACM
Transactions on Programming Languages and Systems. 2018;40(2). doi:10.1145/3174800
apa: Chatterjee, K., Fu, H., Novotný, P., & Hasheminezhad, R. (2018). Algorithmic
analysis of qualitative and quantitative termination problems for affine probabilistic
programs. ACM Transactions on Programming Languages and Systems. Association
for Computing Machinery (ACM). https://doi.org/10.1145/3174800
chicago: Chatterjee, Krishnendu, Hongfei Fu, Petr Novotný, and Rouzbeh Hasheminezhad.
“Algorithmic Analysis of Qualitative and Quantitative Termination Problems for
Affine Probabilistic Programs.” ACM Transactions on Programming Languages and
Systems. Association for Computing Machinery (ACM), 2018. https://doi.org/10.1145/3174800.
ieee: K. Chatterjee, H. Fu, P. Novotný, and R. Hasheminezhad, “Algorithmic analysis
of qualitative and quantitative termination problems for affine probabilistic
programs,” ACM Transactions on Programming Languages and Systems, vol.
40, no. 2. Association for Computing Machinery (ACM), 2018.
ista: Chatterjee K, Fu H, Novotný P, Hasheminezhad R. 2018. Algorithmic analysis
of qualitative and quantitative termination problems for affine probabilistic
programs. ACM Transactions on Programming Languages and Systems. 40(2), 7.
mla: Chatterjee, Krishnendu, et al. “Algorithmic Analysis of Qualitative and Quantitative
Termination Problems for Affine Probabilistic Programs.” ACM Transactions on
Programming Languages and Systems, vol. 40, no. 2, 7, Association for Computing
Machinery (ACM), 2018, doi:10.1145/3174800.
short: K. Chatterjee, H. Fu, P. Novotný, R. Hasheminezhad, ACM Transactions on Programming
Languages and Systems 40 (2018).
date_created: 2019-02-14T12:29:10Z
date_published: 2018-06-01T00:00:00Z
date_updated: 2023-09-19T14:38:42Z
day: '01'
department:
- _id: KrCh
doi: 10.1145/3174800
ec_funded: 1
external_id:
arxiv:
- '1510.08517'
isi:
- '000434634500003'
intvolume: ' 40'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1510.08517
month: '06'
oa: 1
oa_version: Submitted Version
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: ACM Transactions on Programming Languages and Systems
publication_identifier:
issn:
- 0164-0925
publication_status: published
publisher: Association for Computing Machinery (ACM)
quality_controlled: '1'
related_material:
record:
- id: '1438'
relation: earlier_version
status: public
scopus_import: '1'
status: public
title: Algorithmic analysis of qualitative and quantitative termination problems for
affine probabilistic programs
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 40
year: '2018'
...
---
_id: '5999'
abstract:
- lang: eng
text: "We introduce for each quiver Q and each algebraic oriented cohomology theory
A, the cohomological Hall algebra (CoHA) of Q, as the A-homology of the moduli
of representations of the preprojective algebra of Q. This generalizes the K-theoretic
Hall algebra of commuting varieties defined by Schiffmann-Vasserot. When A is
the Morava K-theory, we show evidence that this algebra is a candidate for Lusztig's
reformulated conjecture on modular representations of algebraic groups.\r\nWe
construct an action of the preprojective CoHA on the A-homology of Nakajima quiver
varieties. We compare this with the action of the Borel subalgebra of Yangian
when A is the intersection theory. We also give a shuffle algebra description
of this CoHA in terms of the underlying formal group law of A. As applications,
we obtain a shuffle description of the Yangian. "
article_processing_charge: No
author:
- first_name: Yaping
full_name: Yang, Yaping
last_name: Yang
- first_name: Gufang
full_name: Zhao, Gufang
id: 2BC2AC5E-F248-11E8-B48F-1D18A9856A87
last_name: Zhao
citation:
ama: Yang Y, Zhao G. The cohomological Hall algebra of a preprojective algebra.
Proceedings of the London Mathematical Society. 2018;116(5):1029-1074.
doi:10.1112/plms.12111
apa: Yang, Y., & Zhao, G. (2018). The cohomological Hall algebra of a preprojective
algebra. Proceedings of the London Mathematical Society. Oxford University
Press. https://doi.org/10.1112/plms.12111
chicago: Yang, Yaping, and Gufang Zhao. “The Cohomological Hall Algebra of a Preprojective
Algebra.” Proceedings of the London Mathematical Society. Oxford University
Press, 2018. https://doi.org/10.1112/plms.12111.
ieee: Y. Yang and G. Zhao, “The cohomological Hall algebra of a preprojective algebra,”
Proceedings of the London Mathematical Society, vol. 116, no. 5. Oxford
University Press, pp. 1029–1074, 2018.
ista: Yang Y, Zhao G. 2018. The cohomological Hall algebra of a preprojective algebra.
Proceedings of the London Mathematical Society. 116(5), 1029–1074.
mla: Yang, Yaping, and Gufang Zhao. “The Cohomological Hall Algebra of a Preprojective
Algebra.” Proceedings of the London Mathematical Society, vol. 116, no.
5, Oxford University Press, 2018, pp. 1029–74, doi:10.1112/plms.12111.
short: Y. Yang, G. Zhao, Proceedings of the London Mathematical Society 116 (2018)
1029–1074.
date_created: 2019-02-14T13:14:22Z
date_published: 2018-05-01T00:00:00Z
date_updated: 2023-09-19T14:37:19Z
day: '01'
department:
- _id: TaHa
doi: 10.1112/plms.12111
external_id:
arxiv:
- '1407.7994'
isi:
- '000431506400001'
intvolume: ' 116'
isi: 1
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1407.7994
month: '05'
oa: 1
oa_version: Preprint
page: 1029-1074
publication: Proceedings of the London Mathematical Society
publication_identifier:
issn:
- 0024-6115
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: The cohomological Hall algebra of a preprojective algebra
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 116
year: '2018'
...
---
_id: '5989'
abstract:
- lang: eng
text: Schistosomes are the causative agents of schistosomiasis, a neglected tropical
disease affecting over 230 million people worldwide.Additionally to their major
impact on human health, they are also models of choice in evolutionary biology.
These parasitic flatwormsare unique among the common hermaphroditic trematodes
as they have separate sexes. This so-called “evolutionary scandal”displays a female
heterogametic genetic sex-determination system (ZZ males and ZW females), as well
as a pronounced adult sexualdimorphism. These phenotypic differences are determined
by a shared set of genes in both sexes, potentially leading to intralocussexual
conflicts. To resolve these conflicts in sexually selected traits, molecular mechanisms
such as sex-biased gene expression couldoccur, but parent-of-origin gene expression
also provides an alternative. In this work we investigated the latter mechanism,
that is,genes expressed preferentially from either the maternal or the paternal
allele, inSchistosoma mansonispecies. To this end, tran-scriptomes from male and
female hybrid adults obtained by strain crosses were sequenced. Strain-specific
single nucleotide poly-morphism (SNP) markers allowed us to discriminate the parental
origin, while reciprocal crosses helped to differentiate parentalexpression from
strain-specific expression. We identified genes containing SNPs expressed in a
parent-of-origin manner consistentwith paternal and maternal imprints. Although
the majority of the SNPs was identified in mitochondrial and Z-specific loci,
theremaining SNPs found in male and female transcriptomes were situated in genes
that have the potential to explain sexual differencesin schistosome parasites.
Furthermore, we identified and validated four new Z-specific scaffolds.
article_processing_charge: No
author:
- first_name: Julien
full_name: Kincaid-Smith, Julien
last_name: Kincaid-Smith
- first_name: Marion A L
full_name: Picard, Marion A L
id: 2C921A7A-F248-11E8-B48F-1D18A9856A87
last_name: Picard
orcid: 0000-0002-8101-2518
- first_name: Céline
full_name: Cosseau, Céline
last_name: Cosseau
- first_name: Jérôme
full_name: Boissier, Jérôme
last_name: Boissier
- first_name: Dany
full_name: Severac, Dany
last_name: Severac
- first_name: Christoph
full_name: Grunau, Christoph
last_name: Grunau
- first_name: Eve
full_name: Toulza, Eve
last_name: Toulza
citation:
ama: Kincaid-Smith J, Picard MAL, Cosseau C, et al. Parent-of-Origin-Dependent Gene
Expression in Male and Female Schistosome Parasites. Genome Biology and Evolution.
2018;10(3):840-856. doi:10.1093/gbe/evy037
apa: Kincaid-Smith, J., Picard, M. A. L., Cosseau, C., Boissier, J., Severac, D.,
Grunau, C., & Toulza, E. (2018). Parent-of-Origin-Dependent Gene Expression
in Male and Female Schistosome Parasites. Genome Biology and Evolution.
Oxford University Press. https://doi.org/10.1093/gbe/evy037
chicago: Kincaid-Smith, Julien, Marion A L Picard, Céline Cosseau, Jérôme Boissier,
Dany Severac, Christoph Grunau, and Eve Toulza. “Parent-of-Origin-Dependent Gene
Expression in Male and Female Schistosome Parasites.” Genome Biology and Evolution.
Oxford University Press, 2018. https://doi.org/10.1093/gbe/evy037.
ieee: J. Kincaid-Smith et al., “Parent-of-Origin-Dependent Gene Expression
in Male and Female Schistosome Parasites,” Genome Biology and Evolution,
vol. 10, no. 3. Oxford University Press, pp. 840–856, 2018.
ista: Kincaid-Smith J, Picard MAL, Cosseau C, Boissier J, Severac D, Grunau C, Toulza
E. 2018. Parent-of-Origin-Dependent Gene Expression in Male and Female Schistosome
Parasites. Genome Biology and Evolution. 10(3), 840–856.
mla: Kincaid-Smith, Julien, et al. “Parent-of-Origin-Dependent Gene Expression in
Male and Female Schistosome Parasites.” Genome Biology and Evolution, vol.
10, no. 3, Oxford University Press, 2018, pp. 840–56, doi:10.1093/gbe/evy037.
short: J. Kincaid-Smith, M.A.L. Picard, C. Cosseau, J. Boissier, D. Severac, C.
Grunau, E. Toulza, Genome Biology and Evolution 10 (2018) 840–856.
date_created: 2019-02-14T12:13:52Z
date_published: 2018-03-01T00:00:00Z
date_updated: 2023-09-19T14:39:08Z
day: '01'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1093/gbe/evy037
external_id:
isi:
- '000429483700013'
file:
- access_level: open_access
checksum: 736a459cb77de5824354466bb0331caf
content_type: application/pdf
creator: dernst
date_created: 2019-02-14T12:20:01Z
date_updated: 2020-07-14T12:47:15Z
file_id: '5991'
file_name: 2018_GBE_Kincaid_Smith.pdf
file_size: 529755
relation: main_file
file_date_updated: 2020-07-14T12:47:15Z
has_accepted_license: '1'
intvolume: ' 10'
isi: 1
issue: '3'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 840-856
publication: Genome Biology and Evolution
publication_identifier:
issn:
- 1759-6653
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Parent-of-Origin-Dependent Gene Expression in Male and Female Schistosome Parasites
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 10
year: '2018'
...
---
_id: '6031'
abstract:
- lang: eng
text: We introduce Clover, a new library for efficient computation using low-precision
data, providing mathematical routines required by fundamental methods in optimization
and sparse recovery. Our library faithfully implements variants of stochastic
quantization that guarantee convergence at low precision, and supports data formats
from 4-bit quantized to 32-bit IEEE-754 on current Intel processors. In particular,
we show that 4-bit can be implemented efficiently using Intel AVX despite the
lack of native support for this data format. Experimental results with dot product,
matrix-vector multiplication (MVM), gradient descent (GD), and iterative hard
thresholding (IHT) demonstrate that the attainable speedups are in many cases
close to linear with respect to the reduction of precision due to reduced data
movement. Finally, for GD and IHT, we show examples of absolute speedup achieved
by 4-bit versus 32-bit, by iterating until a given target error is achieved.
article_number: '8598402'
article_processing_charge: No
author:
- first_name: Alen
full_name: Stojanov, Alen
last_name: Stojanov
- first_name: Tyler Michael
full_name: Smith, Tyler Michael
last_name: Smith
- first_name: Dan-Adrian
full_name: Alistarh, Dan-Adrian
id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
last_name: Alistarh
orcid: 0000-0003-3650-940X
- first_name: Markus
full_name: Puschel, Markus
last_name: Puschel
citation:
ama: 'Stojanov A, Smith TM, Alistarh D-A, Puschel M. Fast quantized arithmetic on
x86: Trading compute for data movement. In: 2018 IEEE International Workshop
on Signal Processing Systems. Vol 2018-October. IEEE; 2018. doi:10.1109/SiPS.2018.8598402'
apa: 'Stojanov, A., Smith, T. M., Alistarh, D.-A., & Puschel, M. (2018). Fast
quantized arithmetic on x86: Trading compute for data movement. In 2018 IEEE
International Workshop on Signal Processing Systems (Vol. 2018–October). Cape
Town, South Africa: IEEE. https://doi.org/10.1109/SiPS.2018.8598402'
chicago: 'Stojanov, Alen, Tyler Michael Smith, Dan-Adrian Alistarh, and Markus Puschel.
“Fast Quantized Arithmetic on X86: Trading Compute for Data Movement.” In 2018
IEEE International Workshop on Signal Processing Systems, Vol. 2018–October.
IEEE, 2018. https://doi.org/10.1109/SiPS.2018.8598402.'
ieee: 'A. Stojanov, T. M. Smith, D.-A. Alistarh, and M. Puschel, “Fast quantized
arithmetic on x86: Trading compute for data movement,” in 2018 IEEE International
Workshop on Signal Processing Systems, Cape Town, South Africa, 2018, vol.
2018–October.'
ista: 'Stojanov A, Smith TM, Alistarh D-A, Puschel M. 2018. Fast quantized arithmetic
on x86: Trading compute for data movement. 2018 IEEE International Workshop on
Signal Processing Systems. SiPS: Workshop on Signal Processing Systems vol. 2018–October,
8598402.'
mla: 'Stojanov, Alen, et al. “Fast Quantized Arithmetic on X86: Trading Compute
for Data Movement.” 2018 IEEE International Workshop on Signal Processing Systems,
vol. 2018–October, 8598402, IEEE, 2018, doi:10.1109/SiPS.2018.8598402.'
short: A. Stojanov, T.M. Smith, D.-A. Alistarh, M. Puschel, in:, 2018 IEEE International
Workshop on Signal Processing Systems, IEEE, 2018.
conference:
end_date: 2018-10-24
location: Cape Town, South Africa
name: 'SiPS: Workshop on Signal Processing Systems'
start_date: 2018-10-21
date_created: 2019-02-17T22:59:25Z
date_published: 2018-12-31T00:00:00Z
date_updated: 2023-09-19T14:41:51Z
day: '31'
department:
- _id: DaAl
doi: 10.1109/SiPS.2018.8598402
external_id:
isi:
- '000465106800060'
isi: 1
language:
- iso: eng
month: '12'
oa_version: None
publication: 2018 IEEE International Workshop on Signal Processing Systems
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Fast quantized arithmetic on x86: Trading compute for data movement'
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 2018-October
year: '2018'
...
---
_id: '25'
abstract:
- lang: eng
text: 'Partially observable Markov decision processes (POMDPs) are the standard
models for planning under uncertainty with both finite and infinite horizon. Besides
the well-known discounted-sum objective, indefinite-horizon objective (aka Goal-POMDPs)
is another classical objective for POMDPs. In this case, given a set of target
states and a positive cost for each transition, the optimization objective is
to minimize the expected total cost until a target state is reached. In the literature,
RTDP-Bel or heuristic search value iteration (HSVI) have been used for solving
Goal-POMDPs. Neither of these algorithms has theoretical convergence guarantees,
and HSVI may even fail to terminate its trials. We give the following contributions:
(1) We discuss the challenges introduced in Goal-POMDPs and illustrate how they
prevent the original HSVI from converging. (2) We present a novel algorithm inspired
by HSVI, termed Goal-HSVI, and show that our algorithm has convergence guarantees.
(3) We show that Goal-HSVI outperforms RTDP-Bel on a set of well-known examples.'
acknowledgement: '∗This work has been supported by Vienna Science and Technology Fund
(WWTF) Project ICT15-003, Austrian Science Fund (FWF) NFN Grant No S11407-N23 (RiSE/SHiNE),
and ERC Starting grant (279307: Graph Games). This research was sponsored by the
Army Research Laboratory and was accomplished under Cooperative Agreement Number
W911NF-13-2-0045 (ARL Cyber Security CRA). '
article_processing_charge: No
author:
- first_name: Karel
full_name: Horák, Karel
last_name: Horák
- first_name: Branislav
full_name: Bošanský, Branislav
last_name: Bošanský
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
citation:
ama: 'Horák K, Bošanský B, Chatterjee K. Goal-HSVI: Heuristic search value iteration
for goal-POMDPs. In: Proceedings of the Twenty-Seventh International Joint
Conference on Artificial Intelligence. Vol 2018-July. IJCAI; 2018:4764-4770.
doi:10.24963/ijcai.2018/662'
apa: 'Horák, K., Bošanský, B., & Chatterjee, K. (2018). Goal-HSVI: Heuristic
search value iteration for goal-POMDPs. In Proceedings of the Twenty-Seventh
International Joint Conference on Artificial Intelligence (Vol. 2018–July,
pp. 4764–4770). Stockholm, Sweden: IJCAI. https://doi.org/10.24963/ijcai.2018/662'
chicago: 'Horák, Karel, Branislav Bošanský, and Krishnendu Chatterjee. “Goal-HSVI:
Heuristic Search Value Iteration for Goal-POMDPs.” In Proceedings of the Twenty-Seventh
International Joint Conference on Artificial Intelligence, 2018–July:4764–70.
IJCAI, 2018. https://doi.org/10.24963/ijcai.2018/662.'
ieee: 'K. Horák, B. Bošanský, and K. Chatterjee, “Goal-HSVI: Heuristic search value
iteration for goal-POMDPs,” in Proceedings of the Twenty-Seventh International
Joint Conference on Artificial Intelligence, Stockholm, Sweden, 2018, vol.
2018–July, pp. 4764–4770.'
ista: 'Horák K, Bošanský B, Chatterjee K. 2018. Goal-HSVI: Heuristic search value
iteration for goal-POMDPs. Proceedings of the Twenty-Seventh International Joint
Conference on Artificial Intelligence. IJCAI: International Joint Conference on
Artificial Intelligence vol. 2018–July, 4764–4770.'
mla: 'Horák, Karel, et al. “Goal-HSVI: Heuristic Search Value Iteration for Goal-POMDPs.”
Proceedings of the Twenty-Seventh International Joint Conference on Artificial
Intelligence, vol. 2018–July, IJCAI, 2018, pp. 4764–70, doi:10.24963/ijcai.2018/662.'
short: K. Horák, B. Bošanský, K. Chatterjee, in:, Proceedings of the Twenty-Seventh
International Joint Conference on Artificial Intelligence, IJCAI, 2018, pp. 4764–4770.
conference:
end_date: 2018-07-19
location: Stockholm, Sweden
name: 'IJCAI: International Joint Conference on Artificial Intelligence'
start_date: 2018-07-13
date_created: 2018-12-11T11:44:13Z
date_published: 2018-07-01T00:00:00Z
date_updated: 2023-09-19T14:44:59Z
day: '01'
department:
- _id: KrCh
doi: 10.24963/ijcai.2018/662
ec_funded: 1
external_id:
isi:
- '000764175404127'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.24963/ijcai.2018/662
month: '07'
oa: 1
oa_version: Published Version
page: 4764 - 4770
project:
- _id: 25892FC0-B435-11E9-9278-68D0E5697425
grant_number: ICT15-003
name: Efficient Algorithms for Computer Aided Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
publication: Proceedings of the Twenty-Seventh International Joint Conference on Artificial
Intelligence
publication_status: published
publisher: IJCAI
publist_id: '8030'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Goal-HSVI: Heuristic search value iteration for goal-POMDPs'
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 2018-July
year: '2018'
...
---
_id: '24'
abstract:
- lang: eng
text: Partially-observable Markov decision processes (POMDPs) with discounted-sum
payoff are a standard framework to model a wide range of problems related to decision
making under uncertainty. Traditionally, the goal has been to obtain policies
that optimize the expectation of the discounted-sum payoff. A key drawback of
the expectation measure is that even low probability events with extreme payoff
can significantly affect the expectation, and thus the obtained policies are not
necessarily risk-averse. An alternate approach is to optimize the probability
that the payoff is above a certain threshold, which allows obtaining risk-averse
policies, but ignores optimization of the expectation. We consider the expectation
optimization with probabilistic guarantee (EOPG) problem, where the goal is to
optimize the expectation ensuring that the payoff is above a given threshold with
at least a specified probability. We present several results on the EOPG problem,
including the first algorithm to solve it.
acknowledgement: "This research was supported by the Vienna Science and Technology
Fund (WWTF) grant ICT15-003; Austrian Science Fund (FWF): S11407-N23(RiSE/SHiNE);and
an ERC Start Grant (279307:Graph Games).\r\n"
article_processing_charge: No
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Adrian
full_name: Elgyütt, Adrian
id: 4A2E9DBA-F248-11E8-B48F-1D18A9856A87
last_name: Elgyütt
- first_name: Petr
full_name: Novotny, Petr
id: 3CC3B868-F248-11E8-B48F-1D18A9856A87
last_name: Novotny
- first_name: Owen
full_name: Rouillé, Owen
last_name: Rouillé
citation:
ama: 'Chatterjee K, Elgyütt A, Novotný P, Rouillé O. Expectation optimization with
probabilistic guarantees in POMDPs with discounted-sum objectives. In: Vol 2018.
IJCAI; 2018:4692-4699. doi:10.24963/ijcai.2018/652'
apa: 'Chatterjee, K., Elgyütt, A., Novotný, P., & Rouillé, O. (2018). Expectation
optimization with probabilistic guarantees in POMDPs with discounted-sum objectives
(Vol. 2018, pp. 4692–4699). Presented at the IJCAI: International Joint Conference
on Artificial Intelligence, Stockholm, Sweden: IJCAI. https://doi.org/10.24963/ijcai.2018/652'
chicago: Chatterjee, Krishnendu, Adrian Elgyütt, Petr Novotný, and Owen Rouillé.
“Expectation Optimization with Probabilistic Guarantees in POMDPs with Discounted-Sum
Objectives,” 2018:4692–99. IJCAI, 2018. https://doi.org/10.24963/ijcai.2018/652.
ieee: 'K. Chatterjee, A. Elgyütt, P. Novotný, and O. Rouillé, “Expectation optimization
with probabilistic guarantees in POMDPs with discounted-sum objectives,” presented
at the IJCAI: International Joint Conference on Artificial Intelligence, Stockholm,
Sweden, 2018, vol. 2018, pp. 4692–4699.'
ista: 'Chatterjee K, Elgyütt A, Novotný P, Rouillé O. 2018. Expectation optimization
with probabilistic guarantees in POMDPs with discounted-sum objectives. IJCAI:
International Joint Conference on Artificial Intelligence vol. 2018, 4692–4699.'
mla: Chatterjee, Krishnendu, et al. Expectation Optimization with Probabilistic
Guarantees in POMDPs with Discounted-Sum Objectives. Vol. 2018, IJCAI, 2018,
pp. 4692–99, doi:10.24963/ijcai.2018/652.
short: K. Chatterjee, A. Elgyütt, P. Novotný, O. Rouillé, in:, IJCAI, 2018, pp.
4692–4699.
conference:
end_date: 2018-07-19
location: Stockholm, Sweden
name: 'IJCAI: International Joint Conference on Artificial Intelligence'
start_date: 2018-07-13
date_created: 2018-12-11T11:44:13Z
date_published: 2018-07-01T00:00:00Z
date_updated: 2023-09-19T14:45:48Z
day: '01'
department:
- _id: KrCh
- _id: ToHe
doi: 10.24963/ijcai.2018/652
ec_funded: 1
external_id:
arxiv:
- '1804.10601'
isi:
- '000764175404117'
intvolume: ' 2018'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1804.10601
month: '07'
oa: 1
oa_version: Preprint
page: 4692 - 4699
project:
- _id: 25892FC0-B435-11E9-9278-68D0E5697425
grant_number: ICT15-003
name: Efficient Algorithms for Computer Aided Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
publication_status: published
publisher: IJCAI
publist_id: '8031'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Expectation optimization with probabilistic guarantees in POMDPs with discounted-sum
objectives
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 2018
year: '2018'
...
---
_id: '34'
abstract:
- lang: eng
text: Partially observable Markov decision processes (POMDPs) are widely used in
probabilistic planning problems in which an agent interacts with an environment
using noisy and imprecise sensors. We study a setting in which the sensors are
only partially defined and the goal is to synthesize “weakest” additional sensors,
such that in the resulting POMDP, there is a small-memory policy for the agent
that almost-surely (with probability 1) satisfies a reachability objective. We
show that the problem is NP-complete, and present a symbolic algorithm by encoding
the problem into SAT instances. We illustrate trade-offs between the amount of
memory of the policy and the number of additional sensors on a simple example.
We have implemented our approach and consider three classical POMDP examples from
the literature, and show that in all the examples the number of sensors can be
significantly decreased (as compared to the existing solutions in the literature)
without increasing the complexity of the policies.
alternative_title:
- ICAPS
article_processing_charge: No
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Martin
full_name: Chemlík, Martin
last_name: Chemlík
- first_name: Ufuk
full_name: Topcu, Ufuk
last_name: Topcu
citation:
ama: 'Chatterjee K, Chemlík M, Topcu U. Sensor synthesis for POMDPs with reachability
objectives. In: Vol 2018. AAAI Press; 2018:47-55.'
apa: 'Chatterjee, K., Chemlík, M., & Topcu, U. (2018). Sensor synthesis for
POMDPs with reachability objectives (Vol. 2018, pp. 47–55). Presented at the ICAPS:
International Conference on Automated Planning and Scheduling, Delft, Netherlands:
AAAI Press.'
chicago: Chatterjee, Krishnendu, Martin Chemlík, and Ufuk Topcu. “Sensor Synthesis
for POMDPs with Reachability Objectives,” 2018:47–55. AAAI Press, 2018.
ieee: 'K. Chatterjee, M. Chemlík, and U. Topcu, “Sensor synthesis for POMDPs with
reachability objectives,” presented at the ICAPS: International Conference on
Automated Planning and Scheduling, Delft, Netherlands, 2018, vol. 2018, pp. 47–55.'
ista: 'Chatterjee K, Chemlík M, Topcu U. 2018. Sensor synthesis for POMDPs with
reachability objectives. ICAPS: International Conference on Automated Planning
and Scheduling, ICAPS, vol. 2018, 47–55.'
mla: Chatterjee, Krishnendu, et al. Sensor Synthesis for POMDPs with Reachability
Objectives. Vol. 2018, AAAI Press, 2018, pp. 47–55.
short: K. Chatterjee, M. Chemlík, U. Topcu, in:, AAAI Press, 2018, pp. 47–55.
conference:
end_date: 2018-06-29
location: Delft, Netherlands
name: 'ICAPS: International Conference on Automated Planning and Scheduling'
start_date: 2018-06-24
date_created: 2018-12-11T11:44:16Z
date_published: 2018-06-01T00:00:00Z
date_updated: 2023-09-19T14:44:14Z
day: '01'
department:
- _id: KrCh
ec_funded: 1
external_id:
arxiv:
- '1710.00675'
isi:
- '000492986200006'
intvolume: ' 2018'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1710.00675
month: '06'
oa: 1
oa_version: Preprint
page: 47 - 55
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
publication_status: published
publisher: AAAI Press
publist_id: '8021'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Sensor synthesis for POMDPs with reachability objectives
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 2018
year: '2018'
...
---
_id: '18'
abstract:
- lang: eng
text: An N-superconcentrator is a directed, acyclic graph with N input nodes and
N output nodes such that every subset of the inputs and every subset of the outputs
of same cardinality can be connected by node-disjoint paths. It is known that
linear-size and bounded-degree superconcentrators exist. We prove the existence
of such superconcentrators with asymptotic density 25.3 (where the density is
the number of edges divided by N). The previously best known densities were 28
[12] and 27.4136 [17].
article_processing_charge: No
author:
- first_name: Vladimir
full_name: Kolmogorov, Vladimir
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
- first_name: Michal
full_name: Rolinek, Michal
id: 3CB3BC06-F248-11E8-B48F-1D18A9856A87
last_name: Rolinek
citation:
ama: Kolmogorov V, Rolinek M. Superconcentrators of density 25.3. Ars Combinatoria.
2018;141(10):269-304.
apa: Kolmogorov, V., & Rolinek, M. (2018). Superconcentrators of density 25.3.
Ars Combinatoria. Charles Babbage Research Centre.
chicago: Kolmogorov, Vladimir, and Michal Rolinek. “Superconcentrators of Density
25.3.” Ars Combinatoria. Charles Babbage Research Centre, 2018.
ieee: V. Kolmogorov and M. Rolinek, “Superconcentrators of density 25.3,” Ars
Combinatoria, vol. 141, no. 10. Charles Babbage Research Centre, pp. 269–304,
2018.
ista: Kolmogorov V, Rolinek M. 2018. Superconcentrators of density 25.3. Ars Combinatoria.
141(10), 269–304.
mla: Kolmogorov, Vladimir, and Michal Rolinek. “Superconcentrators of Density 25.3.”
Ars Combinatoria, vol. 141, no. 10, Charles Babbage Research Centre, 2018,
pp. 269–304.
short: V. Kolmogorov, M. Rolinek, Ars Combinatoria 141 (2018) 269–304.
date_created: 2018-12-11T11:44:11Z
date_published: 2018-10-01T00:00:00Z
date_updated: 2023-09-19T14:46:18Z
day: '01'
department:
- _id: VlKo
external_id:
arxiv:
- '1405.7828'
isi:
- '000446809500022'
intvolume: ' 141'
isi: 1
issue: '10'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1405.7828
month: '10'
oa: 1
oa_version: Preprint
page: 269 - 304
publication: Ars Combinatoria
publication_identifier:
issn:
- 0381-7032
publication_status: published
publisher: Charles Babbage Research Centre
publist_id: '8037'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Superconcentrators of density 25.3
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 141
year: '2018'
...
---
_id: '6355'
abstract:
- lang: eng
text: We prove that any cyclic quadrilateral can be inscribed in any closed convex
C1-curve. The smoothness condition is not required if the quadrilateral is a
rectangle.
article_number: e7
article_processing_charge: No
author:
- first_name: Arseniy
full_name: Akopyan, Arseniy
id: 430D2C90-F248-11E8-B48F-1D18A9856A87
last_name: Akopyan
orcid: 0000-0002-2548-617X
- first_name: Sergey
full_name: Avvakumov, Sergey
id: 3827DAC8-F248-11E8-B48F-1D18A9856A87
last_name: Avvakumov
citation:
ama: Akopyan A, Avvakumov S. Any cyclic quadrilateral can be inscribed in any closed
convex smooth curve. Forum of Mathematics, Sigma. 2018;6. doi:10.1017/fms.2018.7
apa: Akopyan, A., & Avvakumov, S. (2018). Any cyclic quadrilateral can be inscribed
in any closed convex smooth curve. Forum of Mathematics, Sigma. Cambridge
University Press. https://doi.org/10.1017/fms.2018.7
chicago: Akopyan, Arseniy, and Sergey Avvakumov. “Any Cyclic Quadrilateral Can Be
Inscribed in Any Closed Convex Smooth Curve.” Forum of Mathematics, Sigma.
Cambridge University Press, 2018. https://doi.org/10.1017/fms.2018.7.
ieee: A. Akopyan and S. Avvakumov, “Any cyclic quadrilateral can be inscribed in
any closed convex smooth curve,” Forum of Mathematics, Sigma, vol. 6. Cambridge
University Press, 2018.
ista: Akopyan A, Avvakumov S. 2018. Any cyclic quadrilateral can be inscribed in
any closed convex smooth curve. Forum of Mathematics, Sigma. 6, e7.
mla: Akopyan, Arseniy, and Sergey Avvakumov. “Any Cyclic Quadrilateral Can Be Inscribed
in Any Closed Convex Smooth Curve.” Forum of Mathematics, Sigma, vol. 6,
e7, Cambridge University Press, 2018, doi:10.1017/fms.2018.7.
short: A. Akopyan, S. Avvakumov, Forum of Mathematics, Sigma 6 (2018).
date_created: 2019-04-30T06:09:57Z
date_published: 2018-05-31T00:00:00Z
date_updated: 2023-09-19T14:50:12Z
day: '31'
ddc:
- '510'
department:
- _id: UlWa
- _id: HeEd
- _id: JaMa
doi: 10.1017/fms.2018.7
ec_funded: 1
external_id:
arxiv:
- '1712.10205'
isi:
- '000433915500001'
file:
- access_level: open_access
checksum: 5a71b24ba712a3eb2e46165a38fbc30a
content_type: application/pdf
creator: dernst
date_created: 2019-04-30T06:14:58Z
date_updated: 2020-07-14T12:47:28Z
file_id: '6356'
file_name: 2018_ForumMahtematics_Akopyan.pdf
file_size: 249246
relation: main_file
file_date_updated: 2020-07-14T12:47:28Z
has_accepted_license: '1'
intvolume: ' 6'
isi: 1
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
project:
- _id: 256E75B8-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '716117'
name: Optimal Transport and Stochastic Dynamics
publication: Forum of Mathematics, Sigma
publication_identifier:
issn:
- 2050-5094
publication_status: published
publisher: Cambridge University Press
quality_controlled: '1'
related_material:
record:
- id: '8156'
relation: dissertation_contains
status: public
status: public
title: Any cyclic quadrilateral can be inscribed in any closed convex smooth curve
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 6
year: '2018'
...
---
_id: '6195'
abstract:
- lang: eng
text: In the context of robotic manipulation and grasping, the shift from a view
that is static (force closure of a single posture) and contact-deprived (only
contact for force closure is allowed, everything else is obstacle) towards a view
that is dynamic and contact-rich (soft manipulation) has led to an increased interest
in soft hands. These hands can easily exploit environmental constraints and object
surfaces without risk, and safely interact with humans, but present also some
challenges. Designing them is difficult, as well as predicting, modelling, and
“programming” their interactions with the objects and the environment. This paper
tackles the problem of simulating them in a fast and effective way, leveraging
on novel and existing simulation technologies. We present a triple-layered simulation
framework where dynamic properties such as stiffness are determined from slow
but accurate FEM simulation data once, and then condensed into a lumped parameter
model that can be used to fast simulate soft fingers and soft hands. We apply
our approach to the simulation of soft pneumatic fingers.
article_number: '8461106'
article_processing_charge: No
author:
- first_name: Maria
full_name: Pozzi, Maria
last_name: Pozzi
- first_name: Eder
full_name: Miguel Villalba, Eder
id: 3FB91342-F248-11E8-B48F-1D18A9856A87
last_name: Miguel Villalba
orcid: 0000-0001-5665-0430
- first_name: Raphael
full_name: Deimel, Raphael
last_name: Deimel
- first_name: Monica
full_name: Malvezzi, Monica
last_name: Malvezzi
- first_name: Bernd
full_name: Bickel, Bernd
id: 49876194-F248-11E8-B48F-1D18A9856A87
last_name: Bickel
orcid: 0000-0001-6511-9385
- first_name: Oliver
full_name: Brock, Oliver
last_name: Brock
- first_name: Domenico
full_name: Prattichizzo, Domenico
last_name: Prattichizzo
citation:
ama: 'Pozzi M, Miguel Villalba E, Deimel R, et al. Efficient FEM-based simulation
of soft robots modeled as kinematic chains. In: IEEE; 2018. doi:10.1109/icra.2018.8461106'
apa: 'Pozzi, M., Miguel Villalba, E., Deimel, R., Malvezzi, M., Bickel, B., Brock,
O., & Prattichizzo, D. (2018). Efficient FEM-based simulation of soft robots
modeled as kinematic chains. Presented at the ICRA: International Conference on
Robotics and Automation, Brisbane, Australia: IEEE. https://doi.org/10.1109/icra.2018.8461106'
chicago: Pozzi, Maria, Eder Miguel Villalba, Raphael Deimel, Monica Malvezzi, Bernd
Bickel, Oliver Brock, and Domenico Prattichizzo. “Efficient FEM-Based Simulation
of Soft Robots Modeled as Kinematic Chains.” IEEE, 2018. https://doi.org/10.1109/icra.2018.8461106.
ieee: 'M. Pozzi et al., “Efficient FEM-based simulation of soft robots modeled
as kinematic chains,” presented at the ICRA: International Conference on Robotics
and Automation, Brisbane, Australia, 2018.'
ista: 'Pozzi M, Miguel Villalba E, Deimel R, Malvezzi M, Bickel B, Brock O, Prattichizzo
D. 2018. Efficient FEM-based simulation of soft robots modeled as kinematic chains.
ICRA: International Conference on Robotics and Automation, 8461106.'
mla: Pozzi, Maria, et al. Efficient FEM-Based Simulation of Soft Robots Modeled
as Kinematic Chains. 8461106, IEEE, 2018, doi:10.1109/icra.2018.8461106.
short: M. Pozzi, E. Miguel Villalba, R. Deimel, M. Malvezzi, B. Bickel, O. Brock,
D. Prattichizzo, in:, IEEE, 2018.
conference:
end_date: 2018-05-25
location: Brisbane, Australia
name: 'ICRA: International Conference on Robotics and Automation'
start_date: 2018-05-21
date_created: 2019-04-04T09:50:38Z
date_published: 2018-09-10T00:00:00Z
date_updated: 2023-09-19T14:49:03Z
day: '10'
department:
- _id: BeBi
doi: 10.1109/icra.2018.8461106
external_id:
isi:
- '000446394503031'
isi: 1
language:
- iso: eng
month: '09'
oa_version: None
publication_identifier:
isbn:
- '9781538630815'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Efficient FEM-based simulation of soft robots modeled as kinematic chains
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '6941'
abstract:
- lang: eng
text: "Bitcoin has become the most successful cryptocurrency ever deployed, and
its most distinctive feature is that it is decentralized. Its underlying protocol
(Nakamoto consensus) achieves this by using proof of work, which has the drawback
that it causes the consumption of vast amounts of energy to maintain the ledger.
Moreover, Bitcoin mining dynamics have become less distributed over time.\r\n\r\nTowards
addressing these issues, we propose SpaceMint, a cryptocurrency based on proofs
of space instead of proofs of work. Miners in SpaceMint dedicate disk space rather
than computation. We argue that SpaceMint’s design solves or alleviates several
of Bitcoin’s issues: most notably, its large energy consumption. SpaceMint also
rewards smaller miners fairly according to their contribution to the network,
thus incentivizing more distributed participation.\r\n\r\nThis paper adapts proof
of space to enable its use in cryptocurrency, studies the attacks that can arise
against a Bitcoin-like blockchain that uses proof of space, and proposes a new
blockchain format and transaction types to address these attacks. Our prototype
shows that initializing 1 TB for mining takes about a day (a one-off setup cost),
and miners spend on average just a fraction of a second per block mined. Finally,
we provide a game-theoretic analysis modeling SpaceMint as an extensive game (the
canonical game-theoretic notion for games that take place over time) and show
that this stylized game satisfies a strong equilibrium notion, thereby arguing
for SpaceMint ’s stability and consensus."
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Sunoo
full_name: Park, Sunoo
last_name: Park
- first_name: Albert
full_name: Kwon, Albert
last_name: Kwon
- first_name: Georg
full_name: Fuchsbauer, Georg
id: 46B4C3EE-F248-11E8-B48F-1D18A9856A87
last_name: Fuchsbauer
- first_name: Peter
full_name: Gazi, Peter
id: 3E0BFE38-F248-11E8-B48F-1D18A9856A87
last_name: Gazi
- first_name: Joel F
full_name: Alwen, Joel F
id: 2A8DFA8C-F248-11E8-B48F-1D18A9856A87
last_name: Alwen
- first_name: Krzysztof Z
full_name: Pietrzak, Krzysztof Z
id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
last_name: Pietrzak
orcid: 0000-0002-9139-1654
citation:
ama: 'Park S, Kwon A, Fuchsbauer G, Gazi P, Alwen JF, Pietrzak KZ. SpaceMint: A
cryptocurrency based on proofs of space. In: 22nd International Conference
on Financial Cryptography and Data Security. Vol 10957. Springer Nature; 2018:480-499.
doi:10.1007/978-3-662-58387-6_26'
apa: 'Park, S., Kwon, A., Fuchsbauer, G., Gazi, P., Alwen, J. F., & Pietrzak,
K. Z. (2018). SpaceMint: A cryptocurrency based on proofs of space. In 22nd
International Conference on Financial Cryptography and Data Security (Vol.
10957, pp. 480–499). Nieuwpoort, Curacao: Springer Nature. https://doi.org/10.1007/978-3-662-58387-6_26'
chicago: 'Park, Sunoo, Albert Kwon, Georg Fuchsbauer, Peter Gazi, Joel F Alwen,
and Krzysztof Z Pietrzak. “SpaceMint: A Cryptocurrency Based on Proofs of Space.”
In 22nd International Conference on Financial Cryptography and Data Security,
10957:480–99. Springer Nature, 2018. https://doi.org/10.1007/978-3-662-58387-6_26.'
ieee: 'S. Park, A. Kwon, G. Fuchsbauer, P. Gazi, J. F. Alwen, and K. Z. Pietrzak,
“SpaceMint: A cryptocurrency based on proofs of space,” in 22nd International
Conference on Financial Cryptography and Data Security, Nieuwpoort, Curacao,
2018, vol. 10957, pp. 480–499.'
ista: 'Park S, Kwon A, Fuchsbauer G, Gazi P, Alwen JF, Pietrzak KZ. 2018. SpaceMint:
A cryptocurrency based on proofs of space. 22nd International Conference on Financial
Cryptography and Data Security. FC: Financial Cryptography and Data Security,
LNCS, vol. 10957, 480–499.'
mla: 'Park, Sunoo, et al. “SpaceMint: A Cryptocurrency Based on Proofs of Space.”
22nd International Conference on Financial Cryptography and Data Security,
vol. 10957, Springer Nature, 2018, pp. 480–99, doi:10.1007/978-3-662-58387-6_26.'
short: S. Park, A. Kwon, G. Fuchsbauer, P. Gazi, J.F. Alwen, K.Z. Pietrzak, in:,
22nd International Conference on Financial Cryptography and Data Security, Springer
Nature, 2018, pp. 480–499.
conference:
end_date: 2018-03-02
location: Nieuwpoort, Curacao
name: 'FC: Financial Cryptography and Data Security'
start_date: 2018-02-26
date_created: 2019-10-14T06:35:38Z
date_published: 2018-12-07T00:00:00Z
date_updated: 2023-09-19T15:02:13Z
day: '07'
department:
- _id: KrPi
doi: 10.1007/978-3-662-58387-6_26
ec_funded: 1
external_id:
isi:
- '000540656400026'
intvolume: ' 10957'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://eprint.iacr.org/2015/528
month: '12'
oa: 1
oa_version: Submitted Version
page: 480-499
project:
- _id: 258AA5B2-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '682815'
name: Teaching Old Crypto New Tricks
publication: 22nd International Conference on Financial Cryptography and Data Security
publication_identifier:
eissn:
- 1611-3349
isbn:
- '9783662583869'
- '9783662583876'
issn:
- 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'SpaceMint: A cryptocurrency based on proofs of space'
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 10957
year: '2018'
...
---
_id: '6497'
abstract:
- lang: eng
text: T cells are actively scanning pMHC-presenting cells in lymphoid organs and
nonlymphoid tissues (NLTs) with divergent topologies and confinement. How the
T cell actomyosin cytoskeleton facilitates this task in distinct environments
is incompletely understood. Here, we show that lack of Myosin IXb (Myo9b), a negative
regulator of the small GTPase Rho, led to increased Rho-GTP levels and cell surface
stiffness in primary T cells. Nonetheless, intravital imaging revealed robust
motility of Myo9b−/− CD8+ T cells in lymphoid tissue and similar expansion and
differentiation during immune responses. In contrast, accumulation of Myo9b−/−
CD8+ T cells in NLTs was strongly impaired. Specifically, Myo9b was required for
T cell crossing of basement membranes, such as those which are present between
dermis and epidermis. As consequence, Myo9b−/− CD8+ T cells showed impaired control
of skin infections. In sum, we show that Myo9b is critical for the CD8+ T cell
adaptation from lymphoid to NLT surveillance and the establishment of protective
tissue–resident T cell populations.
article_processing_charge: No
author:
- first_name: Federica
full_name: Moalli, Federica
last_name: Moalli
- first_name: Xenia
full_name: Ficht, Xenia
last_name: Ficht
- first_name: Philipp
full_name: Germann, Philipp
last_name: Germann
- first_name: Mykhailo
full_name: Vladymyrov, Mykhailo
last_name: Vladymyrov
- first_name: Bettina
full_name: Stolp, Bettina
last_name: Stolp
- first_name: Ingrid
full_name: de Vries, Ingrid
id: 4C7D837E-F248-11E8-B48F-1D18A9856A87
last_name: de Vries
- first_name: Ruth
full_name: Lyck, Ruth
last_name: Lyck
- first_name: Jasmin
full_name: Balmer, Jasmin
last_name: Balmer
- first_name: Amleto
full_name: Fiocchi, Amleto
last_name: Fiocchi
- first_name: Mario
full_name: Kreutzfeldt, Mario
last_name: Kreutzfeldt
- first_name: Doron
full_name: Merkler, Doron
last_name: Merkler
- first_name: Matteo
full_name: Iannacone, Matteo
last_name: Iannacone
- first_name: Akitaka
full_name: Ariga, Akitaka
last_name: Ariga
- first_name: Michael H.
full_name: Stoffel, Michael H.
last_name: Stoffel
- first_name: James
full_name: Sharpe, James
last_name: Sharpe
- first_name: Martin
full_name: Bähler, Martin
last_name: Bähler
- first_name: Michael K
full_name: Sixt, Michael K
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
- first_name: Alba
full_name: Diz-Muñoz, Alba
last_name: Diz-Muñoz
- first_name: Jens V.
full_name: Stein, Jens V.
last_name: Stein
citation:
ama: Moalli F, Ficht X, Germann P, et al. The Rho regulator Myosin IXb enables nonlymphoid
tissue seeding of protective CD8+T cells. The Journal of Experimental Medicine.
2018;2015(7):1869–1890. doi:10.1084/jem.20170896
apa: Moalli, F., Ficht, X., Germann, P., Vladymyrov, M., Stolp, B., de Vries, I.,
… Stein, J. V. (2018). The Rho regulator Myosin IXb enables nonlymphoid tissue
seeding of protective CD8+T cells. The Journal of Experimental Medicine.
Rockefeller University Press. https://doi.org/10.1084/jem.20170896
chicago: Moalli, Federica, Xenia Ficht, Philipp Germann, Mykhailo Vladymyrov, Bettina
Stolp, Ingrid de Vries, Ruth Lyck, et al. “The Rho Regulator Myosin IXb Enables
Nonlymphoid Tissue Seeding of Protective CD8+T Cells.” The Journal of Experimental
Medicine. Rockefeller University Press, 2018. https://doi.org/10.1084/jem.20170896.
ieee: F. Moalli et al., “The Rho regulator Myosin IXb enables nonlymphoid
tissue seeding of protective CD8+T cells,” The Journal of Experimental Medicine,
vol. 2015, no. 7. Rockefeller University Press, pp. 1869–1890, 2018.
ista: Moalli F, Ficht X, Germann P, Vladymyrov M, Stolp B, de Vries I, Lyck R, Balmer
J, Fiocchi A, Kreutzfeldt M, Merkler D, Iannacone M, Ariga A, Stoffel MH, Sharpe
J, Bähler M, Sixt MK, Diz-Muñoz A, Stein JV. 2018. The Rho regulator Myosin IXb
enables nonlymphoid tissue seeding of protective CD8+T cells. The Journal of Experimental
Medicine. 2015(7), 1869–1890.
mla: Moalli, Federica, et al. “The Rho Regulator Myosin IXb Enables Nonlymphoid
Tissue Seeding of Protective CD8+T Cells.” The Journal of Experimental Medicine,
vol. 2015, no. 7, Rockefeller University Press, 2018, pp. 1869–1890, doi:10.1084/jem.20170896.
short: F. Moalli, X. Ficht, P. Germann, M. Vladymyrov, B. Stolp, I. de Vries, R.
Lyck, J. Balmer, A. Fiocchi, M. Kreutzfeldt, D. Merkler, M. Iannacone, A. Ariga,
M.H. Stoffel, J. Sharpe, M. Bähler, M.K. Sixt, A. Diz-Muñoz, J.V. Stein, The Journal
of Experimental Medicine 2015 (2018) 1869–1890.
date_created: 2019-05-28T12:36:47Z
date_published: 2018-06-06T00:00:00Z
date_updated: 2023-09-19T14:52:08Z
day: '06'
ddc:
- '570'
department:
- _id: MiSi
doi: 10.1084/jem.20170896
external_id:
isi:
- '000440822900011'
file:
- access_level: open_access
checksum: 86ae5331f9bfced9a6358a790a04bef4
content_type: application/pdf
creator: kschuh
date_created: 2019-05-28T12:40:05Z
date_updated: 2020-07-14T12:47:32Z
file_id: '6498'
file_name: 2018_rupress_Moalli.pdf
file_size: 3841660
relation: main_file
file_date_updated: 2020-07-14T12:47:32Z
has_accepted_license: '1'
intvolume: ' 2015'
isi: 1
issue: '7'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 1869–1890
publication: The Journal of Experimental Medicine
publication_identifier:
eissn:
- 1540-9538
issn:
- 0022-1007
publication_status: published
publisher: Rockefeller University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective
CD8+T cells
tmp:
image: /images/cc_by_nc_sa.png
legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
BY-NC-SA 4.0)
short: CC BY-NC-SA (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 2015
year: '2018'
...
---
_id: '6499'
abstract:
- lang: eng
text: Expansion microscopy is a recently introduced imaging technique that achieves
super‐resolution through physically expanding the specimen by ~4×, after embedding
into a swellable gel. The resolution attained is, correspondingly, approximately
fourfold better than the diffraction limit, or ~70 nm. This is a major improvement
over conventional microscopy, but still lags behind modern STED or STORM setups,
whose resolution can reach 20–30 nm. We addressed this issue here by introducing
an improved gel recipe that enables an expansion factor of ~10× in each dimension,
which corresponds to an expansion of the sample volume by more than 1,000‐fold.
Our protocol, which we termed X10 microscopy, achieves a resolution of 25–30 nm
on conventional epifluorescence microscopes. X10 provides multi‐color images similar
or even superior to those produced with more challenging methods, such as STED,
STORM, and iterative expansion microscopy (iExM). X10 is therefore the cheapest
and easiest option for high‐quality super‐resolution imaging currently available.
X10 should be usable in any laboratory, irrespective of the machinery owned or
of the technical knowledge.
article_number: e45836
article_processing_charge: No
author:
- first_name: Sven M
full_name: Truckenbrodt, Sven M
id: 45812BD4-F248-11E8-B48F-1D18A9856A87
last_name: Truckenbrodt
- first_name: Manuel
full_name: Maidorn, Manuel
last_name: Maidorn
- first_name: Dagmar
full_name: Crzan, Dagmar
last_name: Crzan
- first_name: Hanna
full_name: Wildhagen, Hanna
last_name: Wildhagen
- first_name: Selda
full_name: Kabatas, Selda
last_name: Kabatas
- first_name: Silvio O
full_name: Rizzoli, Silvio O
last_name: Rizzoli
citation:
ama: Truckenbrodt SM, Maidorn M, Crzan D, Wildhagen H, Kabatas S, Rizzoli SO. X10
expansion microscopy enables 25‐nm resolution on conventional microscopes. EMBO
reports. 2018;19(9). doi:10.15252/embr.201845836
apa: Truckenbrodt, S. M., Maidorn, M., Crzan, D., Wildhagen, H., Kabatas, S., &
Rizzoli, S. O. (2018). X10 expansion microscopy enables 25‐nm resolution on conventional
microscopes. EMBO Reports. EMBO. https://doi.org/10.15252/embr.201845836
chicago: Truckenbrodt, Sven M, Manuel Maidorn, Dagmar Crzan, Hanna Wildhagen, Selda
Kabatas, and Silvio O Rizzoli. “X10 Expansion Microscopy Enables 25‐nm Resolution
on Conventional Microscopes.” EMBO Reports. EMBO, 2018. https://doi.org/10.15252/embr.201845836.
ieee: S. M. Truckenbrodt, M. Maidorn, D. Crzan, H. Wildhagen, S. Kabatas, and S.
O. Rizzoli, “X10 expansion microscopy enables 25‐nm resolution on conventional
microscopes,” EMBO reports, vol. 19, no. 9. EMBO, 2018.
ista: Truckenbrodt SM, Maidorn M, Crzan D, Wildhagen H, Kabatas S, Rizzoli SO. 2018.
X10 expansion microscopy enables 25‐nm resolution on conventional microscopes.
EMBO reports. 19(9), e45836.
mla: Truckenbrodt, Sven M., et al. “X10 Expansion Microscopy Enables 25‐nm Resolution
on Conventional Microscopes.” EMBO Reports, vol. 19, no. 9, e45836, EMBO,
2018, doi:10.15252/embr.201845836.
short: S.M. Truckenbrodt, M. Maidorn, D. Crzan, H. Wildhagen, S. Kabatas, S.O. Rizzoli,
EMBO Reports 19 (2018).
date_created: 2019-05-28T13:16:08Z
date_published: 2018-09-01T00:00:00Z
date_updated: 2023-09-19T14:52:32Z
day: '01'
ddc:
- '580'
department:
- _id: JoDa
doi: 10.15252/embr.201845836
external_id:
isi:
- '000443682200009'
file:
- access_level: open_access
checksum: 6ec90abc637f09cca3a7b6424d7e7a26
content_type: application/pdf
creator: kschuh
date_created: 2019-05-28T13:17:19Z
date_updated: 2020-07-14T12:47:32Z
file_id: '6500'
file_name: 2018_embo_Truckenbrodt.pdf
file_size: 2005572
relation: main_file
file_date_updated: 2020-07-14T12:47:32Z
has_accepted_license: '1'
intvolume: ' 19'
isi: 1
issue: '9'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
publication: EMBO reports
publication_identifier:
eissn:
- 1469-3178
issn:
- 1469-221X
publication_status: published
publisher: EMBO
quality_controlled: '1'
scopus_import: '1'
status: public
title: X10 expansion microscopy enables 25‐nm resolution on conventional microscopes
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 19
year: '2018'
...
---
_id: '7123'
abstract:
- lang: eng
text: "Population protocols are a popular model of distributed computing, in which
n agents with limited local state interact randomly, and cooperate to collectively
compute global predicates. Inspired by recent developments in DNA programming,
an extensive series of papers, across different communities, has examined the
computability and complexity characteristics of this model. Majority, or consensus,
is a central task in this model, in which agents need to collectively reach a
decision as to which one of two states A or B had a higher initial count. Two
metrics are important: the time that a protocol requires to stabilize to an output
decision, and the state space size that each agent requires to do so. It is known
that majority requires Ω(log log n) states per agent to allow for fast (poly-logarithmic
time) stabilization, and that O(log2 n) states are sufficient. Thus, there is
an exponential gap between the space upper and lower bounds for this problem.
This paper addresses this question.\r\n\r\nOn the negative side, we provide a
new lower bound of Ω(log n) states for any protocol which stabilizes in O(n1–c)
expected time, for any constant c > 0. This result is conditional on monotonicity
and output assumptions, satisfied by all known protocols. Technically, it represents
a departure from previous lower bounds, in that it does not rely on the existence
of dense configurations. Instead, we introduce a new generalized surgery technique
to prove the existence of incorrect executions for any algorithm which would contradict
the lower bound. Subsequently, our lower bound also applies to general initial
configurations, including ones with a leader. On the positive side, we give a
new algorithm for majority which uses O(log n) states, and stabilizes in O(log2
n) expected time. Central to the algorithm is a new leaderless phase clock technique,
which allows agents to synchronize in phases of Θ(n log n) consecutive interactions
using O(log n) states per agent, exploiting a new connection between population
protocols and power-of-two-choices load balancing mechanisms. We also employ our
phase clock to build a leader election algorithm with a state space of size O(log
n), which stabilizes in O(log2 n) expected time."
article_processing_charge: No
author:
- first_name: Dan-Adrian
full_name: Alistarh, Dan-Adrian
id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
last_name: Alistarh
orcid: 0000-0003-3650-940X
- first_name: James
full_name: Aspnes, James
last_name: Aspnes
- first_name: Rati
full_name: Gelashvili, Rati
last_name: Gelashvili
citation:
ama: 'Alistarh D-A, Aspnes J, Gelashvili R. Space-optimal majority in population
protocols. In: Proceedings of the 29th Annual ACM-SIAM Symposium on Discrete
Algorithms. ACM; 2018:2221-2239. doi:10.1137/1.9781611975031.144'
apa: 'Alistarh, D.-A., Aspnes, J., & Gelashvili, R. (2018). Space-optimal majority
in population protocols. In Proceedings of the 29th Annual ACM-SIAM Symposium
on Discrete Algorithms (pp. 2221–2239). New Orleans, LA, United States: ACM.
https://doi.org/10.1137/1.9781611975031.144'
chicago: Alistarh, Dan-Adrian, James Aspnes, and Rati Gelashvili. “Space-Optimal
Majority in Population Protocols.” In Proceedings of the 29th Annual ACM-SIAM
Symposium on Discrete Algorithms, 2221–39. ACM, 2018. https://doi.org/10.1137/1.9781611975031.144.
ieee: D.-A. Alistarh, J. Aspnes, and R. Gelashvili, “Space-optimal majority in population
protocols,” in Proceedings of the 29th Annual ACM-SIAM Symposium on Discrete
Algorithms, New Orleans, LA, United States, 2018, pp. 2221–2239.
ista: 'Alistarh D-A, Aspnes J, Gelashvili R. 2018. Space-optimal majority in population
protocols. Proceedings of the 29th Annual ACM-SIAM Symposium on Discrete Algorithms.
SODA: Symposium on Discrete Algorithms, 2221–2239.'
mla: Alistarh, Dan-Adrian, et al. “Space-Optimal Majority in Population Protocols.”
Proceedings of the 29th Annual ACM-SIAM Symposium on Discrete Algorithms,
ACM, 2018, pp. 2221–39, doi:10.1137/1.9781611975031.144.
short: D.-A. Alistarh, J. Aspnes, R. Gelashvili, in:, Proceedings of the 29th Annual
ACM-SIAM Symposium on Discrete Algorithms, ACM, 2018, pp. 2221–2239.
conference:
end_date: 2018-01-10
location: New Orleans, LA, United States
name: 'SODA: Symposium on Discrete Algorithms'
start_date: 2018-01-07
date_created: 2019-11-26T15:10:55Z
date_published: 2018-01-30T00:00:00Z
date_updated: 2023-09-19T15:03:16Z
day: '30'
department:
- _id: DaAl
doi: 10.1137/1.9781611975031.144
external_id:
arxiv:
- '1704.04947'
isi:
- '000483921200145'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1704.04947
month: '01'
oa: 1
oa_version: Preprint
page: 2221-2239
publication: Proceedings of the 29th Annual ACM-SIAM Symposium on Discrete Algorithms
publication_identifier:
isbn:
- '9781611975031'
publication_status: published
publisher: ACM
quality_controlled: '1'
status: public
title: Space-optimal majority in population protocols
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '9917'
abstract:
- lang: eng
text: Adaptive divergence and speciation may happen despite opposition by gene flow.
Identifying the genomic basis underlying divergence with gene flow is a major
task in evolutionary genomics. Most approaches (e.g., outlier scans) focus on
genomic regions of high differentiation. However, not all genomic architectures
potentially underlying divergence are expected to show extreme differentiation.
Here, we develop an approach that combines hybrid zone analysis (i.e., focuses
on spatial patterns of allele frequency change) with system-specific simulations
to identify loci inconsistent with neutral evolution. We apply this to a genome-wide
SNP set from an ideally suited study organism, the intertidal snail Littorina
saxatilis, which shows primary divergence between ecotypes associated with different
shore habitats. We detect many SNPs with clinal patterns, most of which are consistent
with neutrality. Among non-neutral SNPs, most are located within three large putative
inversions differentiating ecotypes. Many non-neutral SNPs show relatively low
levels of differentiation. We discuss potential reasons for this pattern, including
loose linkage to selected variants, polygenic adaptation and a component of balancing
selection within populations (which may be expected for inversions). Our work
is in line with theory predicting a role for inversions in divergence, and emphasizes
that genomic regions contributing to divergence may not always be accessible with
methods purely based on allele frequency differences. These conclusions call for
approaches that take spatial patterns of allele frequency change into account
in other systems.
acknowledgement: We are very grateful to people who helped with fieldwork, snail processing,
and DNA extractions, particularly Laura Brettell, Mårten Duvetorp, Juan Galindo,
Anne-Lise Liabot and Irena Senčić. We would also like to thank Magnus Alm Rosenblad
and Mats Töpel for their contribution to assembling the Littorina saxatilis genome,
Carl André, Pasi Rastas, and Romain Villoutreix for discussion, and two anonymous
reviewers for their helpful comments on the manuscript. We are grateful to RapidGenomics
for library preparation and sequencing. We thank the Natural Environment Research
Council, the European Research Council and the Swedish Research Councils VR and
Formas (Linnaeus grant to the Centre for Marine Evolutionary Biology and Tage Erlander
Guest Professorship) for funding. P.C. was funded by the University of Sheffield
Vice-chancellor's India scholarship. R.F. is funded by the European Union's Horizon
2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement
no. 706376. M. Raf. was supported by the Adlerbert Research Foundation.
article_processing_charge: Yes
article_type: letter_note
author:
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Marina
full_name: Rafajlović, Marina
last_name: Rafajlović
- first_name: Pragya
full_name: Chaube, Pragya
last_name: Chaube
- first_name: Rui
full_name: Faria, Rui
last_name: Faria
- first_name: Tomas
full_name: Larsson, Tomas
last_name: Larsson
- first_name: Marina
full_name: Panova, Marina
last_name: Panova
- first_name: Mark
full_name: Ravinet, Mark
last_name: Ravinet
- first_name: Anders
full_name: Blomberg, Anders
last_name: Blomberg
- first_name: Bernhard
full_name: Mehlig, Bernhard
last_name: Mehlig
- first_name: Kerstin
full_name: Johannesson, Kerstin
last_name: Johannesson
- first_name: Roger
full_name: Butlin, Roger
last_name: Butlin
citation:
ama: 'Westram AM, Rafajlović M, Chaube P, et al. Clines on the seashore: The genomic
architecture underlying rapid divergence in the face of gene flow. Evolution
Letters. 2018;2(4):297-309. doi:10.1002/evl3.74'
apa: 'Westram, A. M., Rafajlović, M., Chaube, P., Faria, R., Larsson, T., Panova,
M., … Butlin, R. (2018). Clines on the seashore: The genomic architecture underlying
rapid divergence in the face of gene flow. Evolution Letters. Wiley. https://doi.org/10.1002/evl3.74'
chicago: 'Westram, Anja M, Marina Rafajlović, Pragya Chaube, Rui Faria, Tomas Larsson,
Marina Panova, Mark Ravinet, et al. “Clines on the Seashore: The Genomic Architecture
Underlying Rapid Divergence in the Face of Gene Flow.” Evolution Letters.
Wiley, 2018. https://doi.org/10.1002/evl3.74.'
ieee: 'A. M. Westram et al., “Clines on the seashore: The genomic architecture
underlying rapid divergence in the face of gene flow,” Evolution Letters,
vol. 2, no. 4. Wiley, pp. 297–309, 2018.'
ista: 'Westram AM, Rafajlović M, Chaube P, Faria R, Larsson T, Panova M, Ravinet
M, Blomberg A, Mehlig B, Johannesson K, Butlin R. 2018. Clines on the seashore:
The genomic architecture underlying rapid divergence in the face of gene flow.
Evolution Letters. 2(4), 297–309.'
mla: 'Westram, Anja M., et al. “Clines on the Seashore: The Genomic Architecture
Underlying Rapid Divergence in the Face of Gene Flow.” Evolution Letters,
vol. 2, no. 4, Wiley, 2018, pp. 297–309, doi:10.1002/evl3.74.'
short: A.M. Westram, M. Rafajlović, P. Chaube, R. Faria, T. Larsson, M. Panova,
M. Ravinet, A. Blomberg, B. Mehlig, K. Johannesson, R. Butlin, Evolution Letters
2 (2018) 297–309.
date_created: 2021-08-16T07:45:38Z
date_published: 2018-08-20T00:00:00Z
date_updated: 2023-09-19T15:08:25Z
day: '20'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1002/evl3.74
external_id:
isi:
- '000446774400004'
pmid:
- '30283683'
file:
- access_level: open_access
checksum: 8524e72507d521416be3f8ccfcd5e3f5
content_type: application/pdf
creator: asandaue
date_created: 2021-08-16T07:48:03Z
date_updated: 2021-08-16T07:48:03Z
file_id: '9918'
file_name: 2018_EvolutionLetters_Westram.pdf
file_size: 764299
relation: main_file
success: 1
file_date_updated: 2021-08-16T07:48:03Z
has_accepted_license: '1'
intvolume: ' 2'
isi: 1
issue: '4'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 297-309
pmid: 1
publication: Evolution Letters
publication_identifier:
eissn:
- 2056-3744
issn:
- 2056-3744
publication_status: published
publisher: Wiley
quality_controlled: '1'
related_material:
record:
- id: '9930'
relation: research_data
status: public
status: public
title: 'Clines on the seashore: The genomic architecture underlying rapid divergence
in the face of gene flow'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 2
year: '2018'
...
---
_id: '9915'
abstract:
- lang: eng
text: 'The evolution of assortative mating is a key part of the speciation process.
Stronger assortment, or greater divergence in mating traits, between species pairs
with overlapping ranges is commonly observed, but possible causes of this pattern
of reproductive character displacement are difficult to distinguish. We use a
multidisciplinary approach to provide a rare example where it is possible to distinguish
among hypotheses concerning the evolution of reproductive character displacement.
We build on an earlier comparative analysis that illustrated a strong pattern
of greater divergence in penis form between pairs of sister species with overlapping
ranges than between allopatric sister-species pairs, in a large clade of marine
gastropods (Littorinidae). We investigate both assortative mating and divergence
in male genitalia in one of the sister-species pairs, discriminating among three
contrasting processes each of which can generate a pattern of reproductive character
displacement: reinforcement, reproductive interference and the Templeton effect.
We demonstrate reproductive character displacement in assortative mating, but
not in genital form between this pair of sister species and use demographic models
to distinguish among the different processes. Our results support a model with
no gene flow since secondary contact and thus favor reproductive interference
as the cause of reproductive character displacement for mate choice, rather than
reinforcement. High gene flow within species argues against the Templeton effect.
Secondary contact appears to have had little impact on genital divergence.'
acknowledgement: The authors express a special thanks to Dr Richard Willan at the
Museum and Art Gallery of the Northern Territory for guidance and support in the
field, and to Carole Smadja for reading and commenting on the manuscript. The authors
thank the Government of Western Australia Department of Parks and Wildlife (license
no. 009254) and Fishery Research Division (exemption no. 2262) for assistance with
permits. Khalid Belkhir modified the coalescent sampler msnsam for the specific
needs of this project and Martin Hirsch helped to set up the ABC pipeline and to
modify the summary statistic calculator mscalc. The authors are grateful to the
Crafoord Foundation for supporting this project. R.K.B., A.M.W., and L.D. were supported
by grants from the Natural Environment Research Council, R.K.B. and A.M.W. were
also supported by the European Research Council and R.K.B. and L.D. by the Leverhulme
Trust. M.M.R. was supported by Consejo Nacional de Ciencia y Tecnología and Secretaría
de Educación Pública, Mexico. G.B. was supported by the Centre for Animal Movement
Research (CAnMove) financed by a Linnaeus grant (No. 349-2007-8690) from the Swedish
Research Council and Lund University.
article_processing_charge: Yes
article_type: letter_note
author:
- first_name: Johan
full_name: Hollander, Johan
last_name: Hollander
- first_name: Mauricio
full_name: Montaño-Rendón, Mauricio
last_name: Montaño-Rendón
- first_name: Giuseppe
full_name: Bianco, Giuseppe
last_name: Bianco
- first_name: Xi
full_name: Yang, Xi
last_name: Yang
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Ludovic
full_name: Duvaux, Ludovic
last_name: Duvaux
- first_name: David G.
full_name: Reid, David G.
last_name: Reid
- first_name: Roger K.
full_name: Butlin, Roger K.
last_name: Butlin
citation:
ama: Hollander J, Montaño-Rendón M, Bianco G, et al. Are assortative mating and
genital divergence driven by reinforcement? Evolution Letters. 2018;2(6):557-566.
doi:10.1002/evl3.85
apa: Hollander, J., Montaño-Rendón, M., Bianco, G., Yang, X., Westram, A. M., Duvaux,
L., … Butlin, R. K. (2018). Are assortative mating and genital divergence driven
by reinforcement? Evolution Letters. Wiley. https://doi.org/10.1002/evl3.85
chicago: Hollander, Johan, Mauricio Montaño-Rendón, Giuseppe Bianco, Xi Yang, Anja
M Westram, Ludovic Duvaux, David G. Reid, and Roger K. Butlin. “Are Assortative
Mating and Genital Divergence Driven by Reinforcement?” Evolution Letters.
Wiley, 2018. https://doi.org/10.1002/evl3.85.
ieee: J. Hollander et al., “Are assortative mating and genital divergence
driven by reinforcement?,” Evolution Letters, vol. 2, no. 6. Wiley, pp.
557–566, 2018.
ista: Hollander J, Montaño-Rendón M, Bianco G, Yang X, Westram AM, Duvaux L, Reid
DG, Butlin RK. 2018. Are assortative mating and genital divergence driven by reinforcement?
Evolution Letters. 2(6), 557–566.
mla: Hollander, Johan, et al. “Are Assortative Mating and Genital Divergence Driven
by Reinforcement?” Evolution Letters, vol. 2, no. 6, Wiley, 2018, pp. 557–66,
doi:10.1002/evl3.85.
short: J. Hollander, M. Montaño-Rendón, G. Bianco, X. Yang, A.M. Westram, L. Duvaux,
D.G. Reid, R.K. Butlin, Evolution Letters 2 (2018) 557–566.
date_created: 2021-08-16T07:30:00Z
date_published: 2018-12-13T00:00:00Z
date_updated: 2023-09-19T15:08:53Z
day: '13'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1002/evl3.85
external_id:
isi:
- '000452990000002'
pmid:
- '30564439'
file:
- access_level: open_access
checksum: 997a78ac41c809975ca69cbdea441f88
content_type: application/pdf
creator: asandaue
date_created: 2021-08-16T07:37:28Z
date_updated: 2021-08-16T07:37:28Z
file_id: '9916'
file_name: 2018_EvolutionLetters_Hollander.pdf
file_size: 584606
relation: main_file
success: 1
file_date_updated: 2021-08-16T07:37:28Z
has_accepted_license: '1'
intvolume: ' 2'
isi: 1
issue: '6'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 557-566
pmid: 1
publication: Evolution Letters
publication_identifier:
eissn:
- 2056-3744
issn:
- ' 2056-3744'
publication_status: published
publisher: Wiley
quality_controlled: '1'
related_material:
record:
- id: '9929'
relation: research_data
status: public
status: public
title: Are assortative mating and genital divergence driven by reinforcement?
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 2
year: '2018'
...
---
_id: '8618'
abstract:
- lang: eng
text: The reversibly switchable fluorescent proteins (RSFPs) commonly used for RESOLFT
nanoscopy have been developed from fluorescent proteins of the GFP superfamily.
These proteins are bright, but exhibit several drawbacks such as relatively large
size, oxygen-dependence, sensitivity to low pH, and limited switching speed. Therefore,
RSFPs from other origins with improved properties need to be explored. Here, we
report the development of two RSFPs based on the LOV domain of the photoreceptor
protein YtvA from Bacillus subtilis. LOV domains obtain their fluorescence by
association with the abundant cellular cofactor flavin mononucleotide (FMN). Under
illumination with blue and ultraviolet light, they undergo a photocycle, making
these proteins inherently photoswitchable. Our first improved variant, rsLOV1,
can be used for RESOLFT imaging, whereas rsLOV2 proved useful for STED nanoscopy
of living cells with a resolution of down to 50 nm. In addition to their smaller
size compared to GFP-related proteins (17 kDa instead of 27 kDa) and their usability
at low pH, rsLOV1 and rsLOV2 exhibit faster switching kinetics, switching on and
off 3 times faster than rsEGFP2, the fastest-switching RSFP reported to date.
Therefore, LOV-domain-based RSFPs have potential for applications where the switching
speed of GFP-based proteins is limiting.
article_number: '2724'
article_processing_charge: No
article_type: original
author:
- first_name: Carola
full_name: Gregor, Carola
last_name: Gregor
- first_name: Sven C.
full_name: Sidenstein, Sven C.
last_name: Sidenstein
- first_name: Martin
full_name: Andresen, Martin
last_name: Andresen
- first_name: Steffen J.
full_name: Sahl, Steffen J.
last_name: Sahl
- first_name: Johann G
full_name: Danzl, Johann G
id: 42EFD3B6-F248-11E8-B48F-1D18A9856A87
last_name: Danzl
orcid: 0000-0001-8559-3973
- first_name: Stefan W.
full_name: Hell, Stefan W.
last_name: Hell
citation:
ama: Gregor C, Sidenstein SC, Andresen M, Sahl SJ, Danzl JG, Hell SW. Novel reversibly
switchable fluorescent proteins for RESOLFT and STED nanoscopy engineered from
the bacterial photoreceptor YtvA. Scientific Reports. 2018;8. doi:10.1038/s41598-018-19947-1
apa: Gregor, C., Sidenstein, S. C., Andresen, M., Sahl, S. J., Danzl, J. G., &
Hell, S. W. (2018). Novel reversibly switchable fluorescent proteins for RESOLFT
and STED nanoscopy engineered from the bacterial photoreceptor YtvA. Scientific
Reports. Springer Nature. https://doi.org/10.1038/s41598-018-19947-1
chicago: Gregor, Carola, Sven C. Sidenstein, Martin Andresen, Steffen J. Sahl, Johann
G Danzl, and Stefan W. Hell. “Novel Reversibly Switchable Fluorescent Proteins
for RESOLFT and STED Nanoscopy Engineered from the Bacterial Photoreceptor YtvA.”
Scientific Reports. Springer Nature, 2018. https://doi.org/10.1038/s41598-018-19947-1.
ieee: C. Gregor, S. C. Sidenstein, M. Andresen, S. J. Sahl, J. G. Danzl, and S.
W. Hell, “Novel reversibly switchable fluorescent proteins for RESOLFT and STED
nanoscopy engineered from the bacterial photoreceptor YtvA,” Scientific Reports,
vol. 8. Springer Nature, 2018.
ista: Gregor C, Sidenstein SC, Andresen M, Sahl SJ, Danzl JG, Hell SW. 2018. Novel
reversibly switchable fluorescent proteins for RESOLFT and STED nanoscopy engineered
from the bacterial photoreceptor YtvA. Scientific Reports. 8, 2724.
mla: Gregor, Carola, et al. “Novel Reversibly Switchable Fluorescent Proteins for
RESOLFT and STED Nanoscopy Engineered from the Bacterial Photoreceptor YtvA.”
Scientific Reports, vol. 8, 2724, Springer Nature, 2018, doi:10.1038/s41598-018-19947-1.
short: C. Gregor, S.C. Sidenstein, M. Andresen, S.J. Sahl, J.G. Danzl, S.W. Hell,
Scientific Reports 8 (2018).
date_created: 2020-10-06T16:33:37Z
date_published: 2018-02-09T00:00:00Z
date_updated: 2023-09-19T15:04:49Z
day: '09'
ddc:
- '570'
department:
- _id: JoDa
doi: 10.1038/s41598-018-19947-1
external_id:
isi:
- '000424630400037'
pmid:
- '29426833'
file:
- access_level: open_access
checksum: e642080fcbde9584c63544f587c74f03
content_type: application/pdf
creator: dernst
date_created: 2020-10-06T16:35:16Z
date_updated: 2020-10-06T16:35:16Z
file_id: '8619'
file_name: 2018_ScientificReports_Gregor.pdf
file_size: 2818077
relation: main_file
success: 1
file_date_updated: 2020-10-06T16:35:16Z
has_accepted_license: '1'
intvolume: ' 8'
isi: 1
keyword:
- Multidisciplinary
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
pmid: 1
publication: Scientific Reports
publication_identifier:
issn:
- 2045-2322
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Novel reversibly switchable fluorescent proteins for RESOLFT and STED nanoscopy
engineered from the bacterial photoreceptor YtvA
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 8
year: '2018'
...
---
_id: '10881'
abstract:
- lang: eng
text: Strigolactones (SLs) are a relatively recent addition to the list of plant
hormones that control different aspects of plant development. SL signalling is
perceived by an α/β hydrolase, DWARF 14 (D14). A close homolog of D14, KARRIKIN
INSENSTIVE2 (KAI2), is involved in perception of an uncharacterized molecule called
karrikin (KAR). Recent studies in Arabidopsis identified the SUPPRESSOR OF MAX2
1 (SMAX1) and SMAX1-LIKE 7 (SMXL7) to be potential SCF–MAX2 complex-mediated proteasome
targets of KAI2 and D14, respectively. Genetic studies on SMXL7 and SMAX1 demonstrated
distinct developmental roles for each, but very little is known about these repressors
in terms of their sequence features. In this study, we performed an extensive
comparative analysis of SMXLs and determined their phylogenetic and evolutionary
history in the plant lineage. Our results show that SMXL family members can be
sub-divided into four distinct phylogenetic clades/classes, with an ancient SMAX1.
Further, we identified the clade-specific motifs that have evolved and that might
act as determinants of SL-KAR signalling specificity. These specificities resulted
from functional diversities among the clades. Our results suggest that a gradual
co-evolution of SMXL members with their upstream receptors D14/KAI2 provided an
increased specificity to both the SL perception and response in land plants.
acknowledgement: "This project received funding from the European Union’s Horizon
2020 research and innovation programme under the Marie Skłodowska-Curie Actions
and it is co-financed by the South Moravian Region under grant agreement No. 665860
(SS). Access to computing and storage facilities owned by parties and projects contributing
to the national grid infrastructure, MetaCentrum, provided under the program ‘Projects
of Large Infrastructure for Research, Development, and Innovations’ (LM2010005)
was greatly appreciated (RSV). The project was funded by The Ministry of Education,
Youth and Sports/MES of the Czech Republic under the project CEITEC 2020 (LQ1601)
(TN, TRM). JF was supported by the European Research Council (project ERC-2011-StG
20101109-PSDP) and the Czech Science Foundation GAČR (GA13-40637S). We thank Dr
Kamel Chibani for active discussions on the evolutionary analysis and Nandan Mysore
Vardarajan for his critical comments on the manuscript. This article reflects\r\nonly
the authors’ views, and the EU is not responsible for any use that may be made of
the information it contains. "
article_processing_charge: No
article_type: original
author:
- first_name: Taraka Ramji
full_name: Moturu, Taraka Ramji
last_name: Moturu
- first_name: Sravankumar
full_name: Thula, Sravankumar
last_name: Thula
- first_name: Ravi Kumar
full_name: Singh, Ravi Kumar
last_name: Singh
- first_name: Tomasz
full_name: Nodzyński, Tomasz
last_name: Nodzyński
- first_name: Radka Svobodová
full_name: Vařeková, Radka Svobodová
last_name: Vařeková
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Sibu
full_name: Simon, Sibu
last_name: Simon
citation:
ama: Moturu TR, Thula S, Singh RK, et al. Molecular evolution and diversification
of the SMXL gene family. Journal of Experimental Botany. 2018;69(9):2367-2378.
doi:10.1093/jxb/ery097
apa: Moturu, T. R., Thula, S., Singh, R. K., Nodzyński, T., Vařeková, R. S., Friml,
J., & Simon, S. (2018). Molecular evolution and diversification of the SMXL
gene family. Journal of Experimental Botany. Oxford University Press. https://doi.org/10.1093/jxb/ery097
chicago: Moturu, Taraka Ramji, Sravankumar Thula, Ravi Kumar Singh, Tomasz Nodzyński,
Radka Svobodová Vařeková, Jiří Friml, and Sibu Simon. “Molecular Evolution and
Diversification of the SMXL Gene Family.” Journal of Experimental Botany.
Oxford University Press, 2018. https://doi.org/10.1093/jxb/ery097.
ieee: T. R. Moturu et al., “Molecular evolution and diversification of the
SMXL gene family,” Journal of Experimental Botany, vol. 69, no. 9. Oxford
University Press, pp. 2367–2378, 2018.
ista: Moturu TR, Thula S, Singh RK, Nodzyński T, Vařeková RS, Friml J, Simon S.
2018. Molecular evolution and diversification of the SMXL gene family. Journal
of Experimental Botany. 69(9), 2367–2378.
mla: Moturu, Taraka Ramji, et al. “Molecular Evolution and Diversification of the
SMXL Gene Family.” Journal of Experimental Botany, vol. 69, no. 9, Oxford
University Press, 2018, pp. 2367–78, doi:10.1093/jxb/ery097.
short: T.R. Moturu, S. Thula, R.K. Singh, T. Nodzyński, R.S. Vařeková, J. Friml,
S. Simon, Journal of Experimental Botany 69 (2018) 2367–2378.
date_created: 2022-03-18T12:43:22Z
date_published: 2018-04-13T00:00:00Z
date_updated: 2023-09-19T15:10:43Z
day: '13'
department:
- _id: JiFr
doi: 10.1093/jxb/ery097
ec_funded: 1
external_id:
isi:
- '000430727000016'
pmid:
- '29538714'
intvolume: ' 69'
isi: 1
issue: '9'
keyword:
- Plant Science
- Physiology
language:
- iso: eng
month: '04'
oa_version: None
page: 2367-2378
pmid: 1
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '282300'
name: Polarity and subcellular dynamics in plants
publication: Journal of Experimental Botany
publication_identifier:
eissn:
- 1460-2431
issn:
- 0022-0957
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Molecular evolution and diversification of the SMXL gene family
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 69
year: '2018'
...
---
_id: '10880'
abstract:
- lang: eng
text: Acquisition of evolutionary novelties is a fundamental process for adapting
to the external environment and invading new niches and results in the diversification
of life, which we can see in the world today. How such novel phenotypic traits
are acquired in the course of evolution and are built up in developing embryos
has been a central question in biology. Whole-genome duplication (WGD) is a process
of genome doubling that supplies raw genetic materials and increases genome complexity.
Recently, it has been gradually revealed that WGD and subsequent fate changes
of duplicated genes can facilitate phenotypic evolution. Here, we review the current
understanding of the relationship between WGD and the acquisition of evolutionary
novelties. We show some examples of this link and discuss how WGD and subsequent
duplicated genes can facilitate phenotypic evolution as well as when such genomic
doubling can be advantageous for adaptation.
acknowledgement: This work was supported by JSPS overseas research fellowships (Y.M.)
and SENSHIN Medical Research Foundation (K.K.T.).
article_processing_charge: No
article_type: original
author:
- first_name: Moriyama
full_name: Yuuta, Moriyama
id: 4968E7C8-F248-11E8-B48F-1D18A9856A87
last_name: Yuuta
orcid: 0000-0002-2853-8051
- first_name: Kazuko
full_name: Koshiba-Takeuchi, Kazuko
last_name: Koshiba-Takeuchi
citation:
ama: Yuuta M, Koshiba-Takeuchi K. Significance of whole-genome duplications on the
emergence of evolutionary novelties. Briefings in Functional Genomics.
2018;17(5):329-338. doi:10.1093/bfgp/ely007
apa: Yuuta, M., & Koshiba-Takeuchi, K. (2018). Significance of whole-genome
duplications on the emergence of evolutionary novelties. Briefings in Functional
Genomics. Oxford University Press. https://doi.org/10.1093/bfgp/ely007
chicago: Yuuta, Moriyama, and Kazuko Koshiba-Takeuchi. “Significance of Whole-Genome
Duplications on the Emergence of Evolutionary Novelties.” Briefings in Functional
Genomics. Oxford University Press, 2018. https://doi.org/10.1093/bfgp/ely007.
ieee: M. Yuuta and K. Koshiba-Takeuchi, “Significance of whole-genome duplications
on the emergence of evolutionary novelties,” Briefings in Functional Genomics,
vol. 17, no. 5. Oxford University Press, pp. 329–338, 2018.
ista: Yuuta M, Koshiba-Takeuchi K. 2018. Significance of whole-genome duplications
on the emergence of evolutionary novelties. Briefings in Functional Genomics.
17(5), 329–338.
mla: Yuuta, Moriyama, and Kazuko Koshiba-Takeuchi. “Significance of Whole-Genome
Duplications on the Emergence of Evolutionary Novelties.” Briefings in Functional
Genomics, vol. 17, no. 5, Oxford University Press, 2018, pp. 329–38, doi:10.1093/bfgp/ely007.
short: M. Yuuta, K. Koshiba-Takeuchi, Briefings in Functional Genomics 17 (2018)
329–338.
date_created: 2022-03-18T12:40:35Z
date_published: 2018-09-01T00:00:00Z
date_updated: 2023-09-19T15:11:22Z
day: '01'
department:
- _id: CaHe
doi: 10.1093/bfgp/ely007
external_id:
isi:
- '000456054400004'
pmid:
- '29579140'
intvolume: ' 17'
isi: 1
issue: '5'
keyword:
- Genetics
- Molecular Biology
- Biochemistry
- General Medicine
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1093/bfgp/ely007
month: '09'
oa: 1
oa_version: Published Version
page: 329-338
pmid: 1
publication: Briefings in Functional Genomics
publication_identifier:
eissn:
- 2041-2657
issn:
- 2041-2649
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Significance of whole-genome duplications on the emergence of evolutionary
novelties
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 17
year: '2018'
...
---
_id: '9930'
abstract:
- lang: eng
text: Adaptive divergence and speciation may happen despite opposition by gene flow.
Identifying the genomic basis underlying divergence with gene flow is a major
task in evolutionary genomics. Most approaches (e.g. outlier scans) focus on genomic
regions of high differentiation. However, not all genomic architectures potentially
underlying divergence are expected to show extreme differentiation. Here, we develop
an approach that combines hybrid zone analysis (i.e. focuses on spatial patterns
of allele frequency change) with system-specific simulations to identify loci
inconsistent with neutral evolution. We apply this to a genome-wide SNP set from
an ideally-suited study organism, the intertidal snail Littorina saxatilis, which
shows primary divergence between ecotypes associated with different shore habitats.
We detect many SNPs with clinal patterns, most of which are consistent with neutrality.
Among non-neutral SNPs, most are located within three large putative inversions
differentiating ecotypes. Many non-neutral SNPs show relatively low levels of
differentiation. We discuss potential reasons for this pattern, including loose
linkage to selected variants, polygenic adaptation and a component of balancing
selection within populations (which may be expected for inversions). Our work
is in line with theory predicting a role for inversions in divergence, and emphasises
that genomic regions contributing to divergence may not always be accessible with
methods purely based on allele frequency differences. These conclusions call for
approaches that take spatial patterns of allele frequency change into account
in other systems.
article_processing_charge: No
author:
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Marina
full_name: Rafajlović, Marina
last_name: Rafajlović
- first_name: Pragya
full_name: Chaube, Pragya
last_name: Chaube
- first_name: Rui
full_name: Faria, Rui
last_name: Faria
- first_name: Tomas
full_name: Larsson, Tomas
last_name: Larsson
- first_name: Marina
full_name: Panova, Marina
last_name: Panova
- first_name: Mark
full_name: Ravinet, Mark
last_name: Ravinet
- first_name: Anders
full_name: Blomberg, Anders
last_name: Blomberg
- first_name: Bernhard
full_name: Mehlig, Bernhard
last_name: Mehlig
- first_name: Kerstin
full_name: Johannesson, Kerstin
last_name: Johannesson
- first_name: Roger
full_name: Butlin, Roger
last_name: Butlin
citation:
ama: 'Westram AM, Rafajlović M, Chaube P, et al. Data from: Clines on the seashore:
the genomic architecture underlying rapid divergence in the face of gene flow.
2018. doi:10.5061/dryad.bp25b65'
apa: 'Westram, A. M., Rafajlović, M., Chaube, P., Faria, R., Larsson, T., Panova,
M., … Butlin, R. (2018). Data from: Clines on the seashore: the genomic architecture
underlying rapid divergence in the face of gene flow. Dryad. https://doi.org/10.5061/dryad.bp25b65'
chicago: 'Westram, Anja M, Marina Rafajlović, Pragya Chaube, Rui Faria, Tomas Larsson,
Marina Panova, Mark Ravinet, et al. “Data from: Clines on the Seashore: The Genomic
Architecture Underlying Rapid Divergence in the Face of Gene Flow.” Dryad, 2018.
https://doi.org/10.5061/dryad.bp25b65.'
ieee: 'A. M. Westram et al., “Data from: Clines on the seashore: the genomic
architecture underlying rapid divergence in the face of gene flow.” Dryad, 2018.'
ista: 'Westram AM, Rafajlović M, Chaube P, Faria R, Larsson T, Panova M, Ravinet
M, Blomberg A, Mehlig B, Johannesson K, Butlin R. 2018. Data from: Clines on the
seashore: the genomic architecture underlying rapid divergence in the face of
gene flow, Dryad, 10.5061/dryad.bp25b65.'
mla: 'Westram, Anja M., et al. Data from: Clines on the Seashore: The Genomic
Architecture Underlying Rapid Divergence in the Face of Gene Flow. Dryad,
2018, doi:10.5061/dryad.bp25b65.'
short: A.M. Westram, M. Rafajlović, P. Chaube, R. Faria, T. Larsson, M. Panova,
M. Ravinet, A. Blomberg, B. Mehlig, K. Johannesson, R. Butlin, (2018).
date_created: 2021-08-17T08:58:47Z
date_published: 2018-07-23T00:00:00Z
date_updated: 2023-09-19T15:08:24Z
day: '23'
department:
- _id: BeVi
doi: 10.5061/dryad.bp25b65
main_file_link:
- open_access: '1'
url: https://doi.org/10.5061/dryad.bp25b65
month: '07'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
record:
- id: '9917'
relation: used_in_publication
status: public
status: public
title: 'Data from: Clines on the seashore: the genomic architecture underlying rapid
divergence in the face of gene flow'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2018'
...
---
_id: '9929'
abstract:
- lang: eng
text: 'The evolution of assortative mating is a key part of the speciation process.
Stronger assortment, or greater divergence in mating traits, between species pairs
with overlapping ranges is commonly observed, but possible causes of this pattern
of reproductive character displacement are difficult to distinguish. We use a
multidisciplinary approach to provide a rare example where it is possible to distinguish
among hypotheses concerning the evolution of reproductive character displacement.
We build on an earlier comparative analysis that illustrated a strong pattern
of greater divergence in penis form between pairs of sister species with overlapping
ranges than between allopatric sister-species pairs, in a large clade of marine
gastropods (Littorinidae). We investigate both assortative mating and divergence
in male genitalia in one of the sister-species pairs, discriminating among three
contrasting processes each of which can generate a pattern of reproductive character
displacement: reinforcement, reproductive interference and the Templeton effect.
We demonstrate reproductive character displacement in assortative mating, but
not in genital form between this pair of sister species and use demographic models
to distinguish among the different processes. Our results support a model with
no gene flow since secondary contact and thus favour reproductive interference
as the cause of reproductive character displacement for mate choice, rather than
reinforcement. High gene flow within species argues against the Templeton effect.
Secondary contact appears to have had little impact on genital divergence.'
article_processing_charge: No
author:
- first_name: Johan
full_name: Hollander, Johan
last_name: Hollander
- first_name: Mauricio
full_name: Montaño-Rendón, Mauricio
last_name: Montaño-Rendón
- first_name: Giuseppe
full_name: Bianco, Giuseppe
last_name: Bianco
- first_name: Xi
full_name: Yang, Xi
last_name: Yang
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Ludovic
full_name: Duvaux, Ludovic
last_name: Duvaux
- first_name: David G.
full_name: Reid, David G.
last_name: Reid
- first_name: Roger K.
full_name: Butlin, Roger K.
last_name: Butlin
citation:
ama: 'Hollander J, Montaño-Rendón M, Bianco G, et al. Data from: Are assortative
mating and genital divergence driven by reinforcement? 2018. doi:10.5061/dryad.51sd2p5'
apa: 'Hollander, J., Montaño-Rendón, M., Bianco, G., Yang, X., Westram, A. M., Duvaux,
L., … Butlin, R. K. (2018). Data from: Are assortative mating and genital divergence
driven by reinforcement? Dryad. https://doi.org/10.5061/dryad.51sd2p5'
chicago: 'Hollander, Johan, Mauricio Montaño-Rendón, Giuseppe Bianco, Xi Yang, Anja
M Westram, Ludovic Duvaux, David G. Reid, and Roger K. Butlin. “Data from: Are
Assortative Mating and Genital Divergence Driven by Reinforcement?” Dryad, 2018.
https://doi.org/10.5061/dryad.51sd2p5.'
ieee: 'J. Hollander et al., “Data from: Are assortative mating and genital
divergence driven by reinforcement?” Dryad, 2018.'
ista: 'Hollander J, Montaño-Rendón M, Bianco G, Yang X, Westram AM, Duvaux L, Reid
DG, Butlin RK. 2018. Data from: Are assortative mating and genital divergence
driven by reinforcement?, Dryad, 10.5061/dryad.51sd2p5.'
mla: 'Hollander, Johan, et al. Data from: Are Assortative Mating and Genital
Divergence Driven by Reinforcement? Dryad, 2018, doi:10.5061/dryad.51sd2p5.'
short: J. Hollander, M. Montaño-Rendón, G. Bianco, X. Yang, A.M. Westram, L. Duvaux,
D.G. Reid, R.K. Butlin, (2018).
date_created: 2021-08-17T08:51:06Z
date_published: 2018-10-17T00:00:00Z
date_updated: 2023-09-19T15:08:53Z
day: '17'
department:
- _id: BeVi
doi: 10.5061/dryad.51sd2p5
main_file_link:
- open_access: '1'
url: https://doi.org/10.5061/dryad.51sd2p5
month: '10'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
record:
- id: '9915'
relation: used_in_publication
status: public
status: public
title: 'Data from: Are assortative mating and genital divergence driven by reinforcement?'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2018'
...
---
_id: '10882'
abstract:
- lang: eng
text: 'We introduce Intelligent Annotation Dialogs for bounding box annotation.
We train an agent to automatically choose a sequence of actions for a human annotator
to produce a bounding box in a minimal amount of time. Specifically, we consider
two actions: box verification [34], where the annotator verifies a box generated
by an object detector, and manual box drawing. We explore two kinds of agents,
one based on predicting the probability that a box will be positively verified,
and the other based on reinforcement learning. We demonstrate that (1) our agents
are able to learn efficient annotation strategies in several scenarios, automatically
adapting to the image difficulty, the desired quality of the boxes, and the detector
strength; (2) in all scenarios the resulting annotation dialogs speed up annotation
compared to manual box drawing alone and box verification alone, while also outperforming
any fixed combination of verification and drawing in most scenarios; (3) in a
realistic scenario where the detector is iteratively re-trained, our agents evolve
a series of strategies that reflect the shifting trade-off between verification
and drawing as the detector grows stronger.'
article_processing_charge: No
author:
- first_name: Jasper
full_name: Uijlings, Jasper
last_name: Uijlings
- first_name: Ksenia
full_name: Konyushkova, Ksenia
last_name: Konyushkova
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
- first_name: Vittorio
full_name: Ferrari, Vittorio
last_name: Ferrari
citation:
ama: 'Uijlings J, Konyushkova K, Lampert C, Ferrari V. Learning intelligent dialogs
for bounding box annotation. In: 2018 IEEE/CVF Conference on Computer Vision
and Pattern Recognition. IEEE; 2018:9175-9184. doi:10.1109/cvpr.2018.00956'
apa: 'Uijlings, J., Konyushkova, K., Lampert, C., & Ferrari, V. (2018). Learning
intelligent dialogs for bounding box annotation. In 2018 IEEE/CVF Conference
on Computer Vision and Pattern Recognition (pp. 9175–9184). Salt Lake City,
UT, United States: IEEE. https://doi.org/10.1109/cvpr.2018.00956'
chicago: Uijlings, Jasper, Ksenia Konyushkova, Christoph Lampert, and Vittorio Ferrari.
“Learning Intelligent Dialogs for Bounding Box Annotation.” In 2018 IEEE/CVF
Conference on Computer Vision and Pattern Recognition, 9175–84. IEEE, 2018.
https://doi.org/10.1109/cvpr.2018.00956.
ieee: J. Uijlings, K. Konyushkova, C. Lampert, and V. Ferrari, “Learning intelligent
dialogs for bounding box annotation,” in 2018 IEEE/CVF Conference on Computer
Vision and Pattern Recognition, Salt Lake City, UT, United States, 2018, pp.
9175–9184.
ista: 'Uijlings J, Konyushkova K, Lampert C, Ferrari V. 2018. Learning intelligent
dialogs for bounding box annotation. 2018 IEEE/CVF Conference on Computer Vision
and Pattern Recognition. CVF: Conference on Computer Vision and Pattern Recognition,
9175–9184.'
mla: Uijlings, Jasper, et al. “Learning Intelligent Dialogs for Bounding Box Annotation.”
2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition, IEEE,
2018, pp. 9175–84, doi:10.1109/cvpr.2018.00956.
short: J. Uijlings, K. Konyushkova, C. Lampert, V. Ferrari, in:, 2018 IEEE/CVF Conference
on Computer Vision and Pattern Recognition, IEEE, 2018, pp. 9175–9184.
conference:
end_date: 2018-06-23
location: Salt Lake City, UT, United States
name: 'CVF: Conference on Computer Vision and Pattern Recognition'
start_date: 2018-06-18
date_created: 2022-03-18T12:45:09Z
date_published: 2018-12-17T00:00:00Z
date_updated: 2023-09-19T15:11:49Z
day: '17'
department:
- _id: ChLa
doi: 10.1109/cvpr.2018.00956
external_id:
arxiv:
- '1712.08087'
isi:
- '000457843609036'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: ' https://doi.org/10.48550/arXiv.1712.08087'
month: '12'
oa: 1
oa_version: Preprint
page: 9175-9184
publication: 2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition
publication_identifier:
eissn:
- 2575-7075
isbn:
- '9781538664209'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Learning intelligent dialogs for bounding box annotation
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '6558'
abstract:
- lang: eng
text: This paper studies the problem of distributed stochastic optimization in an
adversarial setting where, out of m machines which allegedly compute stochastic
gradients every iteration, an α-fraction are Byzantine, and may behave adversarially.
Our main result is a variant of stochastic gradient descent (SGD) which finds
ε-approximate minimizers of convex functions in T=O~(1/ε²m+α²/ε²) iterations.
In contrast, traditional mini-batch SGD needs T=O(1/ε²m) iterations, but cannot
tolerate Byzantine failures. Further, we provide a lower bound showing that, up
to logarithmic factors, our algorithm is information-theoretically optimal both
in terms of sample complexity and time complexity.
article_processing_charge: No
author:
- first_name: Dan-Adrian
full_name: Alistarh, Dan-Adrian
id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
last_name: Alistarh
orcid: 0000-0003-3650-940X
- first_name: Zeyuan
full_name: Allen-Zhu, Zeyuan
last_name: Allen-Zhu
- first_name: Jerry
full_name: Li, Jerry
last_name: Li
citation:
ama: 'Alistarh D-A, Allen-Zhu Z, Li J. Byzantine stochastic gradient descent. In:
Advances in Neural Information Processing Systems. Vol 2018. Neural Information
Processing Systems Foundation; 2018:4613-4623.'
apa: 'Alistarh, D.-A., Allen-Zhu, Z., & Li, J. (2018). Byzantine stochastic
gradient descent. In Advances in Neural Information Processing Systems
(Vol. 2018, pp. 4613–4623). Montreal, Canada: Neural Information Processing Systems
Foundation.'
chicago: Alistarh, Dan-Adrian, Zeyuan Allen-Zhu, and Jerry Li. “Byzantine Stochastic
Gradient Descent.” In Advances in Neural Information Processing Systems,
2018:4613–23. Neural Information Processing Systems Foundation, 2018.
ieee: D.-A. Alistarh, Z. Allen-Zhu, and J. Li, “Byzantine stochastic gradient descent,”
in Advances in Neural Information Processing Systems, Montreal, Canada,
2018, vol. 2018, pp. 4613–4623.
ista: 'Alistarh D-A, Allen-Zhu Z, Li J. 2018. Byzantine stochastic gradient descent.
Advances in Neural Information Processing Systems. NeurIPS: Conference on Neural
Information Processing Systems vol. 2018, 4613–4623.'
mla: Alistarh, Dan-Adrian, et al. “Byzantine Stochastic Gradient Descent.” Advances
in Neural Information Processing Systems, vol. 2018, Neural Information Processing
Systems Foundation, 2018, pp. 4613–23.
short: D.-A. Alistarh, Z. Allen-Zhu, J. Li, in:, Advances in Neural Information
Processing Systems, Neural Information Processing Systems Foundation, 2018, pp.
4613–4623.
conference:
end_date: 2018-12-08
location: Montreal, Canada
name: 'NeurIPS: Conference on Neural Information Processing Systems'
start_date: 2018-12-02
date_created: 2019-06-13T08:22:37Z
date_published: 2018-12-01T00:00:00Z
date_updated: 2023-09-19T15:12:45Z
day: '01'
department:
- _id: DaAl
external_id:
arxiv:
- '1803.08917'
isi:
- '000461823304061'
intvolume: ' 2018'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1803.08917
month: '12'
oa: 1
oa_version: Published Version
page: 4613-4623
publication: Advances in Neural Information Processing Systems
publication_status: published
publisher: Neural Information Processing Systems Foundation
quality_controlled: '1'
scopus_import: '1'
status: public
title: Byzantine stochastic gradient descent
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 2018
year: '2018'
...
---
_id: '6032'
abstract:
- lang: eng
text: The main result of this article is a generalization of the classical blossom
algorithm for finding perfect matchings. Our algorithm can efficiently solve Boolean
CSPs where each variable appears in exactly two constraints (we call it edge CSP)
and all constraints are even Δ-matroid relations (represented by lists of tuples).
As a consequence of this, we settle the complexity classification of planar Boolean
CSPs started by Dvorak and Kupec. Using a reduction to even Δ-matroids, we then
extend the tractability result to larger classes of Δ-matroids that we call efficiently
coverable. It properly includes classes that were known to be tractable before,
namely, co-independent, compact, local, linear, and binary, with the following
caveat:We represent Δ-matroids by lists of tuples, while the last two use a representation
by matrices. Since an n ×n matrix can represent exponentially many tuples, our
tractability result is not strictly stronger than the known algorithm for linear
and binary Δ-matroids.
article_number: '22'
article_processing_charge: No
article_type: original
author:
- first_name: Alexandr
full_name: Kazda, Alexandr
id: 3B32BAA8-F248-11E8-B48F-1D18A9856A87
last_name: Kazda
- first_name: Vladimir
full_name: Kolmogorov, Vladimir
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
- first_name: Michal
full_name: Rolinek, Michal
id: 3CB3BC06-F248-11E8-B48F-1D18A9856A87
last_name: Rolinek
citation:
ama: Kazda A, Kolmogorov V, Rolinek M. Even delta-matroids and the complexity of
planar boolean CSPs. ACM Transactions on Algorithms. 2018;15(2). doi:10.1145/3230649
apa: Kazda, A., Kolmogorov, V., & Rolinek, M. (2018). Even delta-matroids and
the complexity of planar boolean CSPs. ACM Transactions on Algorithms.
ACM. https://doi.org/10.1145/3230649
chicago: Kazda, Alexandr, Vladimir Kolmogorov, and Michal Rolinek. “Even Delta-Matroids
and the Complexity of Planar Boolean CSPs.” ACM Transactions on Algorithms.
ACM, 2018. https://doi.org/10.1145/3230649.
ieee: A. Kazda, V. Kolmogorov, and M. Rolinek, “Even delta-matroids and the complexity
of planar boolean CSPs,” ACM Transactions on Algorithms, vol. 15, no. 2.
ACM, 2018.
ista: Kazda A, Kolmogorov V, Rolinek M. 2018. Even delta-matroids and the complexity
of planar boolean CSPs. ACM Transactions on Algorithms. 15(2), 22.
mla: Kazda, Alexandr, et al. “Even Delta-Matroids and the Complexity of Planar Boolean
CSPs.” ACM Transactions on Algorithms, vol. 15, no. 2, 22, ACM, 2018, doi:10.1145/3230649.
short: A. Kazda, V. Kolmogorov, M. Rolinek, ACM Transactions on Algorithms 15 (2018).
date_created: 2019-02-17T22:59:25Z
date_published: 2018-12-01T00:00:00Z
date_updated: 2023-09-20T11:20:26Z
day: '01'
department:
- _id: VlKo
doi: 10.1145/3230649
ec_funded: 1
external_id:
arxiv:
- '1602.03124'
isi:
- '000468036500007'
intvolume: ' 15'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1602.03124
month: '12'
oa: 1
oa_version: Preprint
project:
- _id: 25FBA906-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '616160'
name: 'Discrete Optimization in Computer Vision: Theory and Practice'
publication: ACM Transactions on Algorithms
publication_status: published
publisher: ACM
quality_controlled: '1'
related_material:
record:
- id: '1192'
relation: earlier_version
status: public
scopus_import: '1'
status: public
title: Even delta-matroids and the complexity of planar boolean CSPs
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 15
year: '2018'
...
---
_id: '200'
abstract:
- lang: eng
text: This thesis is concerned with the inference of current population structure
based on geo-referenced genetic data. The underlying idea is that population structure
affects its spatial genetic structure. Therefore, genotype information can be
utilized to estimate important demographic parameters such as migration rates.
These indirect estimates of population structure have become very attractive,
as genotype data is now widely available. However, there also has been much concern
about these approaches. Importantly, genetic structure can be influenced by many
complex patterns, which often cannot be disentangled. Moreover, many methods merely
fit heuristic patterns of genetic structure, and do not build upon population
genetics theory. Here, I describe two novel inference methods that address these
shortcomings. In Chapter 2, I introduce an inference scheme based on a new type
of signal, identity by descent (IBD) blocks. Recently, it has become feasible
to detect such long blocks of genome shared between pairs of samples. These blocks
are direct traces of recent coalescence events. As such, they contain ample signal
for inferring recent demography. I examine sharing of IBD blocks in two-dimensional
populations with local migration. Using a diffusion approximation, I derive formulas
for an isolation by distance pattern of long IBD blocks and show that sharing
of long IBD blocks approaches rapid exponential decay for growing sample distance.
I describe an inference scheme based on these results. It can robustly estimate
the dispersal rate and population density, which is demonstrated on simulated
data. I also show an application to estimate mean migration and the rate of recent
population growth within Eastern Europe. Chapter 3 is about a novel method to
estimate barriers to gene flow in a two dimensional population. This inference
scheme utilizes geographically localized allele frequency fluctuations - a classical
isolation by distance signal. The strength of these local fluctuations increases
on average next to a barrier, and there is less correlation across it. I again
use a framework of diffusion of ancestral lineages to model this effect, and provide
an efficient numerical implementation to fit the results to geo-referenced biallelic
SNP data. This inference scheme is able to robustly estimate strong barriers to
gene flow, as tests on simulated data confirm.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Harald
full_name: Ringbauer, Harald
id: 417FCFF4-F248-11E8-B48F-1D18A9856A87
last_name: Ringbauer
orcid: 0000-0002-4884-9682
citation:
ama: Ringbauer H. Inferring recent demography from spatial genetic structure. 2018.
doi:10.15479/AT:ISTA:th_963
apa: Ringbauer, H. (2018). Inferring recent demography from spatial genetic structure.
Institute of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:th_963
chicago: Ringbauer, Harald. “Inferring Recent Demography from Spatial Genetic Structure.”
Institute of Science and Technology Austria, 2018. https://doi.org/10.15479/AT:ISTA:th_963.
ieee: H. Ringbauer, “Inferring recent demography from spatial genetic structure,”
Institute of Science and Technology Austria, 2018.
ista: Ringbauer H. 2018. Inferring recent demography from spatial genetic structure.
Institute of Science and Technology Austria.
mla: Ringbauer, Harald. Inferring Recent Demography from Spatial Genetic Structure.
Institute of Science and Technology Austria, 2018, doi:10.15479/AT:ISTA:th_963.
short: H. Ringbauer, Inferring Recent Demography from Spatial Genetic Structure,
Institute of Science and Technology Austria, 2018.
date_created: 2018-12-11T11:45:10Z
date_published: 2018-02-21T00:00:00Z
date_updated: 2023-09-20T12:00:56Z
day: '21'
ddc:
- '576'
degree_awarded: PhD
department:
- _id: NiBa
doi: 10.15479/AT:ISTA:th_963
file:
- access_level: open_access
checksum: 8cc534d2b528ae017acf80874cce48c9
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:14:55Z
date_updated: 2020-07-14T12:45:23Z
file_id: '5111'
file_name: IST-2018-963-v1+1_thesis.pdf
file_size: 5792935
relation: main_file
- access_level: closed
checksum: 6af18d7e5a7e2728ceda2f41ee24f628
content_type: application/zip
creator: dernst
date_created: 2019-04-05T09:30:12Z
date_updated: 2020-07-14T12:45:23Z
file_id: '6224'
file_name: 2018_thesis_ringbauer_source.zip
file_size: 113365
relation: source_file
file_date_updated: 2020-07-14T12:45:23Z
has_accepted_license: '1'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: '146'
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '7713'
pubrep_id: '963'
related_material:
record:
- id: '563'
relation: part_of_dissertation
status: public
- id: '1074'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
title: Inferring recent demography from spatial genetic structure
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '1064'
abstract:
- lang: eng
text: 'In 1945, A.W. Goodman and R.E. Goodman proved the following conjecture by
P. Erdős: Given a family of (round) disks of radii r1, … , rn in the plane, it
is always possible to cover them by a disk of radius R= ∑ ri, provided they cannot
be separated into two subfamilies by a straight line disjoint from the disks.
In this note we show that essentially the same idea may work for different analogues
and generalizations of their result. In particular, we prove the following: Given
a family of positive homothetic copies of a fixed convex body K⊂ Rd with homothety
coefficients τ1, … , τn> 0 , it is always possible to cover them by a translate
of d+12(∑τi)K, provided they cannot be separated into two subfamilies by a hyperplane
disjoint from the homothets.'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Arseniy
full_name: Akopyan, Arseniy
id: 430D2C90-F248-11E8-B48F-1D18A9856A87
last_name: Akopyan
orcid: 0000-0002-2548-617X
- first_name: Alexey
full_name: Balitskiy, Alexey
last_name: Balitskiy
- first_name: Mikhail
full_name: Grigorev, Mikhail
last_name: Grigorev
citation:
ama: Akopyan A, Balitskiy A, Grigorev M. On the circle covering theorem by A.W.
Goodman and R.E. Goodman. Discrete & Computational Geometry. 2018;59(4):1001-1009.
doi:10.1007/s00454-017-9883-x
apa: Akopyan, A., Balitskiy, A., & Grigorev, M. (2018). On the circle covering
theorem by A.W. Goodman and R.E. Goodman. Discrete & Computational Geometry.
Springer. https://doi.org/10.1007/s00454-017-9883-x
chicago: Akopyan, Arseniy, Alexey Balitskiy, and Mikhail Grigorev. “On the Circle
Covering Theorem by A.W. Goodman and R.E. Goodman.” Discrete & Computational
Geometry. Springer, 2018. https://doi.org/10.1007/s00454-017-9883-x.
ieee: A. Akopyan, A. Balitskiy, and M. Grigorev, “On the circle covering theorem
by A.W. Goodman and R.E. Goodman,” Discrete & Computational Geometry,
vol. 59, no. 4. Springer, pp. 1001–1009, 2018.
ista: Akopyan A, Balitskiy A, Grigorev M. 2018. On the circle covering theorem by
A.W. Goodman and R.E. Goodman. Discrete & Computational Geometry. 59(4), 1001–1009.
mla: Akopyan, Arseniy, et al. “On the Circle Covering Theorem by A.W. Goodman and
R.E. Goodman.” Discrete & Computational Geometry, vol. 59, no. 4, Springer,
2018, pp. 1001–09, doi:10.1007/s00454-017-9883-x.
short: A. Akopyan, A. Balitskiy, M. Grigorev, Discrete & Computational Geometry
59 (2018) 1001–1009.
date_created: 2018-12-11T11:49:57Z
date_published: 2018-06-01T00:00:00Z
date_updated: 2023-09-20T12:08:51Z
day: '01'
ddc:
- '516'
- '000'
department:
- _id: HeEd
doi: 10.1007/s00454-017-9883-x
ec_funded: 1
external_id:
isi:
- '000432205500011'
file:
- access_level: open_access
content_type: application/pdf
creator: dernst
date_created: 2019-01-18T09:27:36Z
date_updated: 2019-01-18T09:27:36Z
file_id: '5844'
file_name: 2018_DiscreteComp_Akopyan.pdf
file_size: 482518
relation: main_file
success: 1
file_date_updated: 2019-01-18T09:27:36Z
has_accepted_license: '1'
intvolume: ' 59'
isi: 1
issue: '4'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 1001-1009
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
publication: Discrete & Computational Geometry
publication_identifier:
eissn:
- '14320444'
issn:
- '01795376'
publication_status: published
publisher: Springer
publist_id: '6324'
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the circle covering theorem by A.W. Goodman and R.E. Goodman
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 59
year: '2018'
...
---
_id: '418'
abstract:
- lang: eng
text: "The aim of this thesis was the development of new strategies for optical
and optogenetic control of proliferative and pro-survival signaling, and characterizing
them from the molecular mechanism up to cellular effects. These new light-based
methods have unique features, such as red light as an activator, or the avoidance
of gene delivery, which enable to overcome current limitations, such as light
delivery to target tissues and feasibility as therapeutic approach. A special
focus was placed on implementing these new light-based approaches in pancreatic
β-cells, as β-cells are the key players in diabetes and especially their loss
in number negatively affects disease progression. Currently no treatment options
are available to compensate the lack of functional β-cells in diabetic patients.\r\nIn
a first approach, red-light-activated growth factor receptors, in particular receptor
tyrosine kinases were engineered and characterized. Receptor activation with light
allows spatio-temporal control compared to ligand-based activation, and especially
red light exhibits deeper tissue penetration than other wavelengths of the visible
spectrum. Red-light-activated receptor tyrosine kinases robustly activated major
growth factor related signaling pathways with a high temporal resolution. Moreover,
the remote activation of the proliferative MAPK/Erk pathway by red-light-activated
receptor tyrosine kinases in a pancreatic β-cell line was also achieved, through
one centimeter thick mouse tissue. Although red-light-activated receptor tyrosine
kinases are particularly attractive for applications in animal models due to the
deep tissue penetration of red light, a drawback, especially with regard to translation
into humans, is the requirement of gene therapy.\r\nIn a second approach an endogenous
light-sensitive mechanism was identified and its potential to promote proliferative
and pro-survival signals was explored, towards light-based tissue regeneration
without the need for gene transfer. Blue-green light illumination was found to
be sufficient for the activation of proliferation and survival promoting signaling
pathways in primary pancreatic murine and human islets. Blue-green light also
led to an increase in proliferation of primary islet cells, an effect which was
shown to be mostly β-cell specific in human islets. Moreover, it was demonstrated
that this approach of pancreatic β-cell expansion did not have any negative effect
on the β-cell function, in particular on their insulin secretion capacity. In
contrast, a trend for enhanced insulin secretion under high glucose conditions
after illumination was detected. In order to unravel the detailed characteristics
of this endogenous light-sensitive mechanism, the precise light requirements were
determined. In addition, the expression of light sensing proteins, OPN3 and rhodopsin,
was detected. The observed effects were found to be independent of handling effects
such as temperature differences and cytochrome c oxidase dependent ATP increase,
but they were found to be enhanced through the knockout of OPN3. The exact mechanism
of how islets cells sense light and the identity of the photoreceptor remains
unknown.\r\nSummarized two new light-based systems with unique features were established
that enable the activation of proliferative and pro-survival signaling pathways.
While red-light-activated receptor tyrosine kinases open a new avenue for optogenetics
research, by allowing non-invasive control of signaling in vivo, the identified
endogenous light-sensitive mechanism has the potential to be the basis of a gene
therapy-free therapeutical approach for light-based β-cell expansion."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Eva
full_name: Gschaider-Reichhart, Eva
id: 3FEE232A-F248-11E8-B48F-1D18A9856A87
last_name: Gschaider-Reichhart
orcid: 0000-0002-7218-7738
citation:
ama: Gschaider-Reichhart E. Optical and optogenetic control of proliferation and
survival . 2018. doi:10.15479/AT:ISTA:th_913
apa: Gschaider-Reichhart, E. (2018). Optical and optogenetic control of proliferation
and survival . Institute of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:th_913
chicago: Gschaider-Reichhart, Eva. “Optical and Optogenetic Control of Proliferation
and Survival .” Institute of Science and Technology Austria, 2018. https://doi.org/10.15479/AT:ISTA:th_913.
ieee: E. Gschaider-Reichhart, “Optical and optogenetic control of proliferation
and survival ,” Institute of Science and Technology Austria, 2018.
ista: Gschaider-Reichhart E. 2018. Optical and optogenetic control of proliferation
and survival . Institute of Science and Technology Austria.
mla: Gschaider-Reichhart, Eva. Optical and Optogenetic Control of Proliferation
and Survival . Institute of Science and Technology Austria, 2018, doi:10.15479/AT:ISTA:th_913.
short: E. Gschaider-Reichhart, Optical and Optogenetic Control of Proliferation
and Survival , Institute of Science and Technology Austria, 2018.
date_created: 2018-12-11T11:46:22Z
date_published: 2018-01-08T00:00:00Z
date_updated: 2023-09-22T09:20:10Z
day: '08'
ddc:
- '571'
- '570'
degree_awarded: PhD
department:
- _id: HaJa
doi: 10.15479/AT:ISTA:th_913
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publication_identifier:
issn:
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publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '7405'
pubrep_id: '913'
related_material:
record:
- id: '1441'
relation: part_of_dissertation
status: public
- id: '1678'
relation: part_of_dissertation
status: public
- id: '2084'
relation: part_of_dissertation
status: public
- id: '1028'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Harald L
full_name: Janovjak, Harald L
id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
last_name: Janovjak
orcid: 0000-0002-8023-9315
title: 'Optical and optogenetic control of proliferation and survival '
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '1012'
abstract:
- lang: eng
text: We prove a new central limit theorem (CLT) for the difference of linear eigenvalue
statistics of a Wigner random matrix H and its minor H and find that the fluctuation
is much smaller than the fluctuations of the individual linear statistics, as
a consequence of the strong correlation between the eigenvalues of H and H. In
particular, our theorem identifies the fluctuation of Kerov's rectangular Young
diagrams, defined by the interlacing eigenvalues ofH and H, around their asymptotic
shape, the Vershik'Kerov'Logan'Shepp curve. Young diagrams equipped with the Plancherel
measure follow the same limiting shape. For this, algebraically motivated, ensemble
a CLT has been obtained in Ivanov and Olshanski [20] which is structurally similar
to our result but the variance is different, indicating that the analogy between
the two models has its limitations. Moreover, our theorem shows that Borodin's
result [7] on the convergence of the spectral distribution of Wigner matrices
to a Gaussian free field also holds in derivative sense.
article_processing_charge: No
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Dominik J
full_name: Schröder, Dominik J
id: 408ED176-F248-11E8-B48F-1D18A9856A87
last_name: Schröder
orcid: 0000-0002-2904-1856
citation:
ama: Erdös L, Schröder DJ. Fluctuations of rectangular young diagrams of interlacing
wigner eigenvalues. International Mathematics Research Notices. 2018;2018(10):3255-3298.
doi:10.1093/imrn/rnw330
apa: Erdös, L., & Schröder, D. J. (2018). Fluctuations of rectangular young
diagrams of interlacing wigner eigenvalues. International Mathematics Research
Notices. Oxford University Press. https://doi.org/10.1093/imrn/rnw330
chicago: Erdös, László, and Dominik J Schröder. “Fluctuations of Rectangular Young
Diagrams of Interlacing Wigner Eigenvalues.” International Mathematics Research
Notices. Oxford University Press, 2018. https://doi.org/10.1093/imrn/rnw330.
ieee: L. Erdös and D. J. Schröder, “Fluctuations of rectangular young diagrams of
interlacing wigner eigenvalues,” International Mathematics Research Notices,
vol. 2018, no. 10. Oxford University Press, pp. 3255–3298, 2018.
ista: Erdös L, Schröder DJ. 2018. Fluctuations of rectangular young diagrams of
interlacing wigner eigenvalues. International Mathematics Research Notices. 2018(10),
3255–3298.
mla: Erdös, László, and Dominik J. Schröder. “Fluctuations of Rectangular Young
Diagrams of Interlacing Wigner Eigenvalues.” International Mathematics Research
Notices, vol. 2018, no. 10, Oxford University Press, 2018, pp. 3255–98, doi:10.1093/imrn/rnw330.
short: L. Erdös, D.J. Schröder, International Mathematics Research Notices 2018
(2018) 3255–3298.
date_created: 2018-12-11T11:49:41Z
date_published: 2018-05-18T00:00:00Z
date_updated: 2023-09-22T09:44:21Z
day: '18'
department:
- _id: LaEr
doi: 10.1093/imrn/rnw330
ec_funded: 1
external_id:
arxiv:
- '1608.05163'
isi:
- '000441668300009'
intvolume: ' 2018'
isi: 1
issue: '10'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1608.05163
month: '05'
oa: 1
oa_version: Preprint
page: 3255-3298
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '338804'
name: Random matrices, universality and disordered quantum systems
publication: International Mathematics Research Notices
publication_identifier:
issn:
- '10737928'
publication_status: published
publisher: Oxford University Press
publist_id: '6383'
quality_controlled: '1'
related_material:
record:
- id: '6179'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Fluctuations of rectangular young diagrams of interlacing wigner eigenvalues
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 2018
year: '2018'
...
---
_id: '6006'
abstract:
- lang: eng
text: 'Network games (NGs) are played on directed graphs and are extensively used
in network design and analysis. Search problems for NGs include finding special
strategy profiles such as a Nash equilibrium and a globally-optimal solution.
The networks modeled by NGs may be huge. In formal verification, abstraction has
proven to be an extremely effective technique for reasoning about systems with
big and even infinite state spaces. We describe an abstraction-refinement methodology
for reasoning about NGs. Our methodology is based on an abstraction function that
maps the state space of an NG to a much smaller state space. We search for a global
optimum and a Nash equilibrium by reasoning on an under- and an over-approximation
defined on top of this smaller state space. When the approximations are too coarse
to find such profiles, we refine the abstraction function. We extend the abstraction-refinement
methodology to labeled networks, where the objectives of the players are regular
languages. Our experimental results demonstrate the effectiveness of the methodology. '
article_number: '39'
author:
- first_name: Guy
full_name: Avni, Guy
id: 463C8BC2-F248-11E8-B48F-1D18A9856A87
last_name: Avni
orcid: 0000-0001-5588-8287
- first_name: Shibashis
full_name: Guha, Shibashis
last_name: Guha
- first_name: Orna
full_name: Kupferman, Orna
last_name: Kupferman
citation:
ama: Avni G, Guha S, Kupferman O. An abstraction-refinement methodology for reasoning
about network games. Games. 2018;9(3). doi:10.3390/g9030039
apa: Avni, G., Guha, S., & Kupferman, O. (2018). An abstraction-refinement methodology
for reasoning about network games. Games. MDPI AG. https://doi.org/10.3390/g9030039
chicago: Avni, Guy, Shibashis Guha, and Orna Kupferman. “An Abstraction-Refinement
Methodology for Reasoning about Network Games.” Games. MDPI AG, 2018. https://doi.org/10.3390/g9030039.
ieee: G. Avni, S. Guha, and O. Kupferman, “An abstraction-refinement methodology
for reasoning about network games,” Games, vol. 9, no. 3. MDPI AG, 2018.
ista: Avni G, Guha S, Kupferman O. 2018. An abstraction-refinement methodology for
reasoning about network games. Games. 9(3), 39.
mla: Avni, Guy, et al. “An Abstraction-Refinement Methodology for Reasoning about
Network Games.” Games, vol. 9, no. 3, 39, MDPI AG, 2018, doi:10.3390/g9030039.
short: G. Avni, S. Guha, O. Kupferman, Games 9 (2018).
date_created: 2019-02-14T14:17:54Z
date_published: 2018-09-01T00:00:00Z
date_updated: 2023-09-22T09:48:59Z
day: '01'
ddc:
- '004'
department:
- _id: ToHe
doi: 10.3390/g9030039
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creator: kschuh
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intvolume: ' 9'
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language:
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month: '09'
oa: 1
oa_version: Published Version
project:
- _id: 264B3912-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: M02369
name: Formal Methods meets Algorithmic Game Theory
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z211
name: The Wittgenstein Prize
publication: Games
publication_identifier:
issn:
- 2073-4336
publication_status: published
publisher: MDPI AG
quality_controlled: '1'
related_material:
record:
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relation: earlier_version
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scopus_import: 1
status: public
title: An abstraction-refinement methodology for reasoning about network games
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2018'
...
---
_id: '35'
abstract:
- lang: eng
text: 'We consider planning problems for graphs, Markov decision processes (MDPs),
and games on graphs. While graphs represent the most basic planning model, MDPs
represent interaction with nature and games on graphs represent interaction with
an adversarial environment. We consider two planning problems where there are
k different target sets, and the problems are as follows: (a) the coverage problem
asks whether there is a plan for each individual target set; and (b) the sequential
target reachability problem asks whether the targets can be reached in sequence.
For the coverage problem, we present a linear-time algorithm for graphs, and quadratic
conditional lower bound for MDPs and games on graphs. For the sequential target
problem, we present a linear-time algorithm for graphs, a sub-quadratic algorithm
for MDPs, and a quadratic conditional lower bound for games on graphs. Our results
with conditional lower bounds establish (i) model-separation results showing that
for the coverage problem MDPs and games on graphs are harder than graphs and for
the sequential reachability problem games on graphs are harder than MDPs and graphs;
and (ii) objective-separation results showing that for MDPs the coverage problem
is harder than the sequential target problem.'
article_processing_charge: No
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Wolfgang
full_name: Dvorák, Wolfgang
last_name: Dvorák
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Alexander
full_name: Svozil, Alexander
last_name: Svozil
citation:
ama: 'Chatterjee K, Dvorák W, Henzinger MH, Svozil A. Algorithms and conditional
lower bounds for planning problems. In: 28th International Conference on Automated
Planning and Scheduling . AAAI Press; 2018.'
apa: 'Chatterjee, K., Dvorák, W., Henzinger, M. H., & Svozil, A. (2018). Algorithms
and conditional lower bounds for planning problems. In 28th International Conference
on Automated Planning and Scheduling . Delft, Netherlands: AAAI Press.'
chicago: Chatterjee, Krishnendu, Wolfgang Dvorák, Monika H Henzinger, and Alexander
Svozil. “Algorithms and Conditional Lower Bounds for Planning Problems.” In 28th
International Conference on Automated Planning and Scheduling . AAAI Press,
2018.
ieee: K. Chatterjee, W. Dvorák, M. H. Henzinger, and A. Svozil, “Algorithms and
conditional lower bounds for planning problems,” in 28th International Conference
on Automated Planning and Scheduling , Delft, Netherlands, 2018.
ista: 'Chatterjee K, Dvorák W, Henzinger MH, Svozil A. 2018. Algorithms and conditional
lower bounds for planning problems. 28th International Conference on Automated
Planning and Scheduling . ICAPS: International Conference on Automated Planning
and Scheduling.'
mla: Chatterjee, Krishnendu, et al. “Algorithms and Conditional Lower Bounds for
Planning Problems.” 28th International Conference on Automated Planning and
Scheduling , AAAI Press, 2018.
short: K. Chatterjee, W. Dvorák, M.H. Henzinger, A. Svozil, in:, 28th International
Conference on Automated Planning and Scheduling , AAAI Press, 2018.
conference:
end_date: 2018-06-29
location: Delft, Netherlands
name: 'ICAPS: International Conference on Automated Planning and Scheduling'
start_date: 2018-06-24
date_created: 2018-12-11T11:44:17Z
date_published: 2018-06-01T00:00:00Z
date_updated: 2023-09-26T10:41:41Z
day: '01'
department:
- _id: KrCh
ec_funded: 1
external_id:
arxiv:
- '1804.07031'
isi:
- '000492986200007'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1804.07031
month: '06'
oa: 1
oa_version: None
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
publication: '28th International Conference on Automated Planning and Scheduling '
publication_status: published
publisher: AAAI Press
publist_id: '8020'
quality_controlled: '1'
related_material:
record:
- id: '9293'
relation: later_version
status: public
scopus_import: '1'
status: public
title: Algorithms and conditional lower bounds for planning problems
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '738'
abstract:
- lang: eng
text: 'This paper is devoted to automatic competitive analysis of real-time scheduling
algorithms for firm-deadline tasksets, where only completed tasks con- tribute
some utility to the system. Given such a taskset T , the competitive ratio of
an on-line scheduling algorithm A for T is the worst-case utility ratio of A over
the utility achieved by a clairvoyant algorithm. We leverage the theory of quantitative
graph games to address the competitive analysis and competitive synthesis problems.
For the competitive analysis case, given any taskset T and any finite-memory on-
line scheduling algorithm A , we show that the competitive ratio of A in T can
be computed in polynomial time in the size of the state space of A . Our approach
is flexible as it also provides ways to model meaningful constraints on the released
task sequences that determine the competitive ratio. We provide an experimental
study of many well-known on-line scheduling algorithms, which demonstrates the
feasibility of our competitive analysis approach that effectively replaces human
ingenuity (required Preliminary versions of this paper have appeared in Chatterjee
et al. ( 2013 , 2014 ). B Andreas Pavlogiannis pavlogiannis@ist.ac.at Krishnendu
Chatterjee krish.chat@ist.ac.at Alexander Kößler koe@ecs.tuwien.ac.at Ulrich Schmid
s@ecs.tuwien.ac.at 1 IST Austria (Institute of Science and Technology Austria),
Am Campus 1, 3400 Klosterneuburg, Austria 2 Embedded Computing Systems Group,
Vienna University of Technology, Treitlstrasse 3, 1040 Vienna, Austria 123 Real-Time
Syst for finding worst-case scenarios) by computing power. For the competitive
synthesis case, we are just given a taskset T , and the goal is to automatically
synthesize an opti- mal on-line scheduling algorithm A , i.e., one that guarantees
the largest competitive ratio possible for T . We show how the competitive synthesis
problem can be reduced to a two-player graph game with partial information, and
establish that the compu- tational complexity of solving this game is Np -complete.
The competitive synthesis problem is hence in Np in the size of the state space
of the non-deterministic labeled transition system encoding the taskset. Overall,
the proposed framework assists in the selection of suitable scheduling algorithms
for a given taskset, which is in fact the most common situation in real-time systems
design. '
article_processing_charge: No
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Andreas
full_name: Pavlogiannis, Andreas
id: 49704004-F248-11E8-B48F-1D18A9856A87
last_name: Pavlogiannis
orcid: 0000-0002-8943-0722
- first_name: Alexander
full_name: Kößler, Alexander
last_name: Kößler
- first_name: Ulrich
full_name: Schmid, Ulrich
last_name: Schmid
citation:
ama: Chatterjee K, Pavlogiannis A, Kößler A, Schmid U. Automated competitive analysis
of real time scheduling with graph games. Real-Time Systems. 2018;54(1):166-207.
doi:10.1007/s11241-017-9293-4
apa: Chatterjee, K., Pavlogiannis, A., Kößler, A., & Schmid, U. (2018). Automated
competitive analysis of real time scheduling with graph games. Real-Time Systems.
Springer. https://doi.org/10.1007/s11241-017-9293-4
chicago: Chatterjee, Krishnendu, Andreas Pavlogiannis, Alexander Kößler, and Ulrich
Schmid. “Automated Competitive Analysis of Real Time Scheduling with Graph Games.”
Real-Time Systems. Springer, 2018. https://doi.org/10.1007/s11241-017-9293-4.
ieee: K. Chatterjee, A. Pavlogiannis, A. Kößler, and U. Schmid, “Automated competitive
analysis of real time scheduling with graph games,” Real-Time Systems,
vol. 54, no. 1. Springer, pp. 166–207, 2018.
ista: Chatterjee K, Pavlogiannis A, Kößler A, Schmid U. 2018. Automated competitive
analysis of real time scheduling with graph games. Real-Time Systems. 54(1), 166–207.
mla: Chatterjee, Krishnendu, et al. “Automated Competitive Analysis of Real Time
Scheduling with Graph Games.” Real-Time Systems, vol. 54, no. 1, Springer,
2018, pp. 166–207, doi:10.1007/s11241-017-9293-4.
short: K. Chatterjee, A. Pavlogiannis, A. Kößler, U. Schmid, Real-Time Systems 54
(2018) 166–207.
date_created: 2018-12-11T11:48:14Z
date_published: 2018-01-01T00:00:00Z
date_updated: 2023-09-27T12:52:38Z
day: '01'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1007/s11241-017-9293-4
ec_funded: 1
external_id:
isi:
- '000419955500006'
file:
- access_level: open_access
checksum: c2590ef160709d8054cf29ee173f1454
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:17:14Z
date_updated: 2020-07-14T12:47:56Z
file_id: '5267'
file_name: IST-2018-960-v1+1_2017_Chatterjee_Automated_competetive.pdf
file_size: 1163507
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has_accepted_license: '1'
intvolume: ' 54'
isi: 1
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 166 - 207
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
name: Microsoft Research Faculty Fellowship
publication: Real-Time Systems
publication_status: published
publisher: Springer
publist_id: '6929'
pubrep_id: '960'
quality_controlled: '1'
related_material:
record:
- id: '2820'
relation: earlier_version
status: public
scopus_import: '1'
status: public
title: Automated competitive analysis of real time scheduling with graph games
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 54
year: '2018'
...
---
_id: '52'
abstract:
- lang: eng
text: In this thesis we will discuss systems of point interacting fermions, their
stability and other spectral properties. Whereas for bosons a point interacting
system is always unstable this ques- tion is more subtle for a gas of two species
of fermions. In particular the answer depends on the mass ratio between these
two species. Most of this work will be focused on the N + M model which consists
of two species of fermions with N, M particles respectively which interact via
point interactions. We will introduce this model using a formal limit and discuss
the N + 1 system in more detail. In particular, we will show that for mass ratios
above a critical one, which does not depend on the particle number, the N + 1
system is stable. In the context of this model we will prove rigorous versions
of Tan relations which relate various quantities of the point-interacting model.
By restricting the N + 1 system to a box we define a finite density model with
point in- teractions. In the context of this system we will discuss the energy
change when introducing a point-interacting impurity into a system of non-interacting
fermions. We will see that this change in energy is bounded independently of the
particle number and in particular the bound only depends on the density and the
scattering length. As another special case of the N + M model we will show stability
of the 2 + 2 model for mass ratios in an interval around one. Further we will
investigate a different model of point interactions which was discussed before
in the literature and which is, contrary to the N + M model, not given by a limiting
procedure but is based on a Dirichlet form. We will show that this system behaves
trivially in the thermodynamic limit, i.e. the free energy per particle is the
same as the one of the non-interacting system.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Thomas
full_name: Moser, Thomas
id: 2B5FC9A4-F248-11E8-B48F-1D18A9856A87
last_name: Moser
citation:
ama: Moser T. Point interactions in systems of fermions. 2018. doi:10.15479/AT:ISTA:th_1043
apa: Moser, T. (2018). Point interactions in systems of fermions. Institute
of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:th_1043
chicago: Moser, Thomas. “Point Interactions in Systems of Fermions.” Institute of
Science and Technology Austria, 2018. https://doi.org/10.15479/AT:ISTA:th_1043.
ieee: T. Moser, “Point interactions in systems of fermions,” Institute of Science
and Technology Austria, 2018.
ista: Moser T. 2018. Point interactions in systems of fermions. Institute of Science
and Technology Austria.
mla: Moser, Thomas. Point Interactions in Systems of Fermions. Institute
of Science and Technology Austria, 2018, doi:10.15479/AT:ISTA:th_1043.
short: T. Moser, Point Interactions in Systems of Fermions, Institute of Science
and Technology Austria, 2018.
date_created: 2018-12-11T11:44:22Z
date_published: 2018-09-04T00:00:00Z
date_updated: 2023-09-27T12:34:14Z
day: '04'
ddc:
- '515'
- '530'
- '519'
degree_awarded: PhD
department:
- _id: RoSe
doi: 10.15479/AT:ISTA:th_1043
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date_created: 2019-04-09T07:45:38Z
date_updated: 2020-07-14T12:46:37Z
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file_name: 2018_Thesis_Moser.pdf
file_size: 851164
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creator: dernst
date_created: 2019-04-09T07:45:38Z
date_updated: 2020-07-14T12:46:37Z
file_id: '6257'
file_name: 2018_Thesis_Moser_Source.zip
file_size: 1531516
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has_accepted_license: '1'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: '115'
project:
- _id: 25C878CE-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P27533_N27
name: Structure of the Excitation Spectrum for Many-Body Quantum Systems
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '8002'
pubrep_id: '1043'
related_material:
record:
- id: '5856'
relation: part_of_dissertation
status: public
- id: '154'
relation: part_of_dissertation
status: public
- id: '1198'
relation: part_of_dissertation
status: public
- id: '741'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
title: Point interactions in systems of fermions
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '913'
abstract:
- lang: eng
text: Coordinated cell polarization in developing tissues is a recurrent theme in
multicellular organisms. In plants, a directional distribution of the plant hormone
auxin is at the core of many developmental programs. A feedback regulation of
auxin on the polarized localization of PIN auxin transporters in individual cells
has been proposed as a self-organizing mechanism for coordinated tissue polarization,
but the molecular mechanisms linking auxin signalling to PIN-dependent auxin transport
remain unknown. We performed a microarray-based approach to find regulators of
the auxin-induced PIN relocation in the Arabidopsis thaliana root. We identified
a subset of a family of phosphatidylinositol transfer proteins (PITP), the PATELLINs
(PATL). Here, we show that PATLs are expressed in partially overlapping cells
types in different tissues going through mitosis or initiating differentiation
programs. PATLs are plasma membrane-associated proteins accumulated in Arabidopsis
embryos, primary roots, lateral root primordia, and developing stomata. Higher
order patl mutants display reduced PIN1 repolarization in response to auxin, shorter
root apical meristem, and drastic defects in embryo and seedling development.
This suggests PATLs redundantly play a crucial role in polarity and patterning
in Arabidopsis.
article_number: jcs.204198
article_processing_charge: No
author:
- first_name: Ricardo
full_name: Tejos, Ricardo
last_name: Tejos
- first_name: Cecilia
full_name: Rodríguez Furlán, Cecilia
last_name: Rodríguez Furlán
- first_name: Maciek
full_name: Adamowski, Maciek
id: 45F536D2-F248-11E8-B48F-1D18A9856A87
last_name: Adamowski
orcid: 0000-0001-6463-5257
- first_name: Michael
full_name: Sauer, Michael
last_name: Sauer
- first_name: Lorena
full_name: Norambuena, Lorena
last_name: Norambuena
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Tejos R, Rodríguez Furlán C, Adamowski M, Sauer M, Norambuena L, Friml J. PATELLINS
are regulators of auxin mediated PIN1 relocation and plant development in Arabidopsis
thaliana. Journal of Cell Science. 2018;131(2). doi:10.1242/jcs.204198
apa: Tejos, R., Rodríguez Furlán, C., Adamowski, M., Sauer, M., Norambuena, L.,
& Friml, J. (2018). PATELLINS are regulators of auxin mediated PIN1 relocation
and plant development in Arabidopsis thaliana. Journal of Cell Science.
Company of Biologists. https://doi.org/10.1242/jcs.204198
chicago: Tejos, Ricardo, Cecilia Rodríguez Furlán, Maciek Adamowski, Michael Sauer,
Lorena Norambuena, and Jiří Friml. “PATELLINS Are Regulators of Auxin Mediated
PIN1 Relocation and Plant Development in Arabidopsis Thaliana.” Journal of
Cell Science. Company of Biologists, 2018. https://doi.org/10.1242/jcs.204198.
ieee: R. Tejos, C. Rodríguez Furlán, M. Adamowski, M. Sauer, L. Norambuena, and
J. Friml, “PATELLINS are regulators of auxin mediated PIN1 relocation and plant
development in Arabidopsis thaliana,” Journal of Cell Science, vol. 131,
no. 2. Company of Biologists, 2018.
ista: Tejos R, Rodríguez Furlán C, Adamowski M, Sauer M, Norambuena L, Friml J.
2018. PATELLINS are regulators of auxin mediated PIN1 relocation and plant development
in Arabidopsis thaliana. Journal of Cell Science. 131(2), jcs. 204198.
mla: Tejos, Ricardo, et al. “PATELLINS Are Regulators of Auxin Mediated PIN1 Relocation
and Plant Development in Arabidopsis Thaliana.” Journal of Cell Science,
vol. 131, no. 2, jcs. 204198, Company of Biologists, 2018, doi:10.1242/jcs.204198.
short: R. Tejos, C. Rodríguez Furlán, M. Adamowski, M. Sauer, L. Norambuena, J.
Friml, Journal of Cell Science 131 (2018).
date_created: 2018-12-11T11:49:10Z
date_published: 2018-01-29T00:00:00Z
date_updated: 2023-09-26T15:47:50Z
day: '29'
ddc:
- '581'
department:
- _id: JiFr
doi: 10.1242/jcs.204198
ec_funded: 1
external_id:
isi:
- '000424842400019'
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content_type: application/pdf
creator: dernst
date_created: 2019-04-12T08:46:32Z
date_updated: 2020-07-14T12:48:15Z
file_id: '6299'
file_name: 2017_adamowski_PATELLINS_are.pdf
file_size: 14925985
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has_accepted_license: '1'
intvolume: ' 131'
isi: 1
issue: '2'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '282300'
name: Polarity and subcellular dynamics in plants
publication: Journal of Cell Science
publication_identifier:
issn:
- '00219533'
publication_status: published
publisher: Company of Biologists
publist_id: '6530'
pubrep_id: '988'
quality_controlled: '1'
scopus_import: '1'
status: public
title: PATELLINS are regulators of auxin mediated PIN1 relocation and plant development
in Arabidopsis thaliana
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 131
year: '2018'
...
---
_id: '69'
abstract:
- lang: eng
text: 'A qubit, a unit of quantum information, is essentially any quantum mechanical
two-level system which can be coherently controlled. Still, to be used for computation,
it has to fulfill criteria. Qubits, regardless of the system in which they are
realized, suffer from decoherence. This leads to loss of the information stored
in the qubit. The upper bound of the time scale on which decoherence happens is
set by the spin relaxation time. In this thesis I studied a two-level system consisting
of a Zeeman-split hole spin confined in a quantum dot formed in a Ge hut wire.
Such Ge hut wires have emerged as a promising material system for the realization
of spin qubits, due to the combination of two significant properties: long spin
coherence time as expected for group IV semiconductors due to the low hyperfine
interaction and a strong valence band spin-orbit coupling. Here, I present how
to fabricate quantum dot devices suitable for electrical transport measurements.
Coupled quantum dot devices allowed the realization of a charge sensor, which
is electrostatically and tunnel coupled to a quantum dot. By integrating the charge
sensor into a radio-frequency reflectometry setup, I performed for the first time
single-shot readout measurements of hole spins and extracted the hole spin relaxation
times in Ge hut wires.'
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Lada
full_name: Vukušić, Lada
id: 31E9F056-F248-11E8-B48F-1D18A9856A87
last_name: Vukušić
orcid: 0000-0003-2424-8636
citation:
ama: Vukušić L. Charge sensing and spin relaxation times of holes in Ge hut wires.
2018. doi:10.15479/AT:ISTA:TH_1047
apa: Vukušić, L. (2018). Charge sensing and spin relaxation times of holes in
Ge hut wires. Institute of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:TH_1047
chicago: Vukušić, Lada. “Charge Sensing and Spin Relaxation Times of Holes in Ge
Hut Wires.” Institute of Science and Technology Austria, 2018. https://doi.org/10.15479/AT:ISTA:TH_1047.
ieee: L. Vukušić, “Charge sensing and spin relaxation times of holes in Ge hut wires,”
Institute of Science and Technology Austria, 2018.
ista: Vukušić L. 2018. Charge sensing and spin relaxation times of holes in Ge hut
wires. Institute of Science and Technology Austria.
mla: Vukušić, Lada. Charge Sensing and Spin Relaxation Times of Holes in Ge Hut
Wires. Institute of Science and Technology Austria, 2018, doi:10.15479/AT:ISTA:TH_1047.
short: L. Vukušić, Charge Sensing and Spin Relaxation Times of Holes in Ge Hut Wires,
Institute of Science and Technology Austria, 2018.
date_created: 2018-12-11T11:44:28Z
date_published: 2018-09-01T00:00:00Z
date_updated: 2023-09-26T15:50:22Z
day: '01'
ddc:
- '530'
- '600'
degree_awarded: PhD
department:
- _id: GeKa
- _id: GradSch
doi: 10.15479/AT:ISTA:TH_1047
file:
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checksum: c570b656e30749cd65b1c7e13a9ce0a8
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creator: dernst
date_created: 2019-04-09T07:00:40Z
date_updated: 2020-07-14T12:47:44Z
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file_name: 2018_Thesis_Vukusic.pdf
file_size: 28452385
relation: main_file
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checksum: 7856771d9cd401fe0b311191076db6e1
content_type: application/zip
creator: dernst
date_created: 2019-04-09T07:00:40Z
date_updated: 2020-07-14T12:47:44Z
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file_name: 2018_Thesis_Vukusic_source.zip
file_size: 53058704
relation: source_file
file_date_updated: 2020-07-14T12:47:44Z
has_accepted_license: '1'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: '103'
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '7985'
pubrep_id: '1047'
related_material:
record:
- id: '23'
relation: part_of_dissertation
status: public
- id: '840'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Georgios
full_name: Katsaros, Georgios
id: 38DB5788-F248-11E8-B48F-1D18A9856A87
last_name: Katsaros
orcid: 0000-0001-8342-202X
title: Charge sensing and spin relaxation times of holes in Ge hut wires
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '324'
abstract:
- lang: eng
text: Neuronal networks in the brain consist of two main types of neuron, glutamatergic
principal neurons and GABAergic interneurons. Although these interneurons only
represent 10–20% of the whole population, they mediate feedback and feedforward
inhibition and are involved in the generation of high-frequency network oscillations.
A hallmark functional property of GABAergic interneurons, especially of the parvalbumin‑expressing
(PV+) subtypes, is the speed of signaling at their output synapse across species
and brain regions. Several molecular and subcellular factors may underlie the
submillisecond signaling at GABAergic synapses. Such as the selective use of P/Q
type Ca2+ channels and the tight coupling between Ca2+ channels and Ca2+ sensors
of exocytosis. However, whether the molecular identity of the release sensor contributes
to these signaling properties remains unclear. Besides, these interneurons are
mainly show depression in response to train of stimuli. How could they keep sufficient
release to control the activity of postsynaptic principal neurons during high
network activity, is largely elusive. For my Ph.D. work, we firstly examined the
Ca2+ sensor of exocytosis at the GABAergic basket cell (BC) to Purkinje cell (PC)
synapse in the cerebellum. Immunolabeling suggested that BC terminals selectively
expressed synaptotagmin 2 (Syt2), whereas synaptotagmin 1 (Syt1) was enriched
in excitatory terminals. Genetic elimination of Syt2 reduced action potential-evoked
release to ~10% compared to the wild-type control, identifying Syt2 as the major
Ca2+ sensor at BC‑PC synapses. Differential adenovirus-mediated rescue revealed
Syt2 triggered release with shorter latency and higher temporal precision, and
mediated faster vesicle pool replenishment than Syt1. Furthermore, deletion of
Syt2 severely reduced and delayed disynaptic inhibition following parallel fiber
stimulation. Thus, the selective use of Syt2 as the release sensor at BC–PC synapse
ensures fast feedforward inhibition in cerebellar microcircuits. Additionally,
we tested the function of another synaptotagmin member, Syt7, for inhibitory synaptic
transmission at the BC–PC synapse. Syt7 is thought to be a Ca2+ sensor that mediates
asynchronous transmitter release and facilitation at synapses. However, it is
strongly expressed in fast-spiking, PV+ GABAergic interneurons and the output
synapses of these neurons produce only minimal asynchronous release and show depression
rather than facilitation. How could Syt7, a facilitation sensor, contribute to
the depressed inhibitory synaptic transmission needs to be further investigated
and understood. Our results indicated that at the BC–PC synapse, Syt7 contributes
to asynchronous release, pool replenishment and facilitation. In combination,
these three effects ensure efficient transmitter release during high‑frequency
activity and guarantee frequency independence of inhibition. Taken together, our
results confirmed that Syt2, which has the fastest kinetic properties among all
synaptotagmin members, is mainly used by the inhibitory BC‑PC synapse for synaptic
transmission, contributing to the speed and temporal precision of transmitter
release. Furthermore, we showed that Syt7, another highly expressed synaptotagmin
member in the output synapses of cerebellar BCs, is used for ensuring efficient
inhibitor synaptic transmission during high activity.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Chong
full_name: Chen, Chong
id: 3DFD581A-F248-11E8-B48F-1D18A9856A87
last_name: Chen
citation:
ama: Chen C. Synaptotagmins ensure speed and efficiency of inhibitory neurotransmitter
release. 2018. doi:10.15479/AT:ISTA:th_997
apa: Chen, C. (2018). Synaptotagmins ensure speed and efficiency of inhibitory
neurotransmitter release. Institute of Science and Technology Austria. https://doi.org/10.15479/AT:ISTA:th_997
chicago: Chen, Chong. “Synaptotagmins Ensure Speed and Efficiency of Inhibitory
Neurotransmitter Release.” Institute of Science and Technology Austria, 2018.
https://doi.org/10.15479/AT:ISTA:th_997.
ieee: C. Chen, “Synaptotagmins ensure speed and efficiency of inhibitory neurotransmitter
release,” Institute of Science and Technology Austria, 2018.
ista: Chen C. 2018. Synaptotagmins ensure speed and efficiency of inhibitory neurotransmitter
release. Institute of Science and Technology Austria.
mla: Chen, Chong. Synaptotagmins Ensure Speed and Efficiency of Inhibitory Neurotransmitter
Release. Institute of Science and Technology Austria, 2018, doi:10.15479/AT:ISTA:th_997.
short: C. Chen, Synaptotagmins Ensure Speed and Efficiency of Inhibitory Neurotransmitter
Release, Institute of Science and Technology Austria, 2018.
date_created: 2018-12-11T11:45:49Z
date_published: 2018-03-01T00:00:00Z
date_updated: 2023-09-27T12:26:03Z
day: '01'
ddc:
- '571'
degree_awarded: PhD
department:
- _id: PeJo
doi: 10.15479/AT:ISTA:th_997
file:
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checksum: 8e163ae9e927401b9fa7c1b3e6a3631a
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:13:58Z
date_updated: 2020-07-14T12:46:04Z
file_id: '5046'
file_name: IST-2018-997-v1+1_Thesis_chong_a.pdf
file_size: 8719458
relation: main_file
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checksum: f7d7260029a5fbb5c982db61328ade52
content_type: application/octet-stream
creator: dernst
date_created: 2019-04-05T09:25:26Z
date_updated: 2020-07-14T12:46:04Z
file_id: '6221'
file_name: 2018_Thesis_chong_source.pages
file_size: 47841940
relation: source_file
file_date_updated: 2020-07-14T12:46:04Z
has_accepted_license: '1'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: '110'
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '7541'
pubrep_id: '997'
related_material:
record:
- id: '1117'
relation: part_of_dissertation
status: public
- id: '749'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
title: Synaptotagmins ensure speed and efficiency of inhibitory neurotransmitter release
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2018'
...
---
_id: '742'
abstract:
- lang: eng
text: 'We give a detailed and easily accessible proof of Gromov’s Topological Overlap
Theorem. Let X be a finite simplicial complex or, more generally, a finite polyhedral
cell complex of dimension d. Informally, the theorem states that if X has sufficiently
strong higher-dimensional expansion properties (which generalize edge expansion
of graphs and are defined in terms of cellular cochains of X) then X has the following
topological overlap property: for every continuous map (Formula presented.) there
exists a point (Formula presented.) that is contained in the images of a positive
fraction (Formula presented.) of the d-cells of X. More generally, the conclusion
holds if (Formula presented.) is replaced by any d-dimensional piecewise-linear
manifold M, with a constant (Formula presented.) that depends only on d and on
the expansion properties of X, but not on M.'
article_processing_charge: Yes (via OA deal)
author:
- first_name: Dominic
full_name: Dotterrer, Dominic
last_name: Dotterrer
- first_name: Tali
full_name: Kaufman, Tali
last_name: Kaufman
- first_name: Uli
full_name: Wagner, Uli
id: 36690CA2-F248-11E8-B48F-1D18A9856A87
last_name: Wagner
orcid: 0000-0002-1494-0568
citation:
ama: Dotterrer D, Kaufman T, Wagner U. On expansion and topological overlap. Geometriae
Dedicata. 2018;195(1):307–317. doi:10.1007/s10711-017-0291-4
apa: Dotterrer, D., Kaufman, T., & Wagner, U. (2018). On expansion and topological
overlap. Geometriae Dedicata. Springer. https://doi.org/10.1007/s10711-017-0291-4
chicago: Dotterrer, Dominic, Tali Kaufman, and Uli Wagner. “On Expansion and Topological
Overlap.” Geometriae Dedicata. Springer, 2018. https://doi.org/10.1007/s10711-017-0291-4.
ieee: D. Dotterrer, T. Kaufman, and U. Wagner, “On expansion and topological overlap,”
Geometriae Dedicata, vol. 195, no. 1. Springer, pp. 307–317, 2018.
ista: Dotterrer D, Kaufman T, Wagner U. 2018. On expansion and topological overlap.
Geometriae Dedicata. 195(1), 307–317.
mla: Dotterrer, Dominic, et al. “On Expansion and Topological Overlap.” Geometriae
Dedicata, vol. 195, no. 1, Springer, 2018, pp. 307–317, doi:10.1007/s10711-017-0291-4.
short: D. Dotterrer, T. Kaufman, U. Wagner, Geometriae Dedicata 195 (2018) 307–317.
date_created: 2018-12-11T11:48:16Z
date_published: 2018-08-01T00:00:00Z
date_updated: 2023-09-27T12:29:57Z
day: '01'
ddc:
- '514'
- '516'
department:
- _id: UlWa
doi: 10.1007/s10711-017-0291-4
external_id:
isi:
- '000437122700017'
file:
- access_level: open_access
checksum: d2f70fc132156504aa4c626aa378a7ab
content_type: application/pdf
creator: kschuh
date_created: 2019-01-15T13:44:05Z
date_updated: 2020-07-14T12:47:58Z
file_id: '5835'
file_name: s10711-017-0291-4.pdf
file_size: 412486
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file_date_updated: 2020-07-14T12:47:58Z
has_accepted_license: '1'
intvolume: ' 195'
isi: 1
issue: '1'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 307–317
project:
- _id: 25FA3206-B435-11E9-9278-68D0E5697425
grant_number: PP00P2_138948
name: 'Embeddings in Higher Dimensions: Algorithms and Combinatorics'
publication: Geometriae Dedicata
publication_status: published
publisher: Springer
publist_id: '6925'
pubrep_id: '912'
quality_controlled: '1'
related_material:
record:
- id: '1378'
relation: earlier_version
status: public
scopus_import: '1'
status: public
title: On expansion and topological overlap
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 195
year: '2018'
...
---
_id: '70'
abstract:
- lang: eng
text: We consider the totally asymmetric simple exclusion process in a critical
scaling parametrized by a≥0, which creates a shock in the particle density of
order aT−1/3, T the observation time. When starting from step initial data, we
provide bounds on the limiting law which in particular imply that in the double
limit lima→∞limT→∞ one recovers the product limit law and the degeneration of
the correlation length observed at shocks of order 1. This result is shown to
apply to a general last-passage percolation model. We also obtain bounds on the
two-point functions of several airy processes.
article_processing_charge: No
article_type: original
author:
- first_name: Peter
full_name: Nejjar, Peter
id: 4BF426E2-F248-11E8-B48F-1D18A9856A87
last_name: Nejjar
citation:
ama: Nejjar P. Transition to shocks in TASEP and decoupling of last passage times.
Latin American Journal of Probability and Mathematical Statistics. 2018;15(2):1311-1334.
doi:10.30757/ALEA.v15-49
apa: Nejjar, P. (2018). Transition to shocks in TASEP and decoupling of last passage
times. Latin American Journal of Probability and Mathematical Statistics.
Instituto Nacional de Matematica Pura e Aplicada. https://doi.org/10.30757/ALEA.v15-49
chicago: Nejjar, Peter. “Transition to Shocks in TASEP and Decoupling of Last Passage
Times.” Latin American Journal of Probability and Mathematical Statistics.
Instituto Nacional de Matematica Pura e Aplicada, 2018. https://doi.org/10.30757/ALEA.v15-49.
ieee: P. Nejjar, “Transition to shocks in TASEP and decoupling of last passage times,”
Latin American Journal of Probability and Mathematical Statistics, vol.
15, no. 2. Instituto Nacional de Matematica Pura e Aplicada, pp. 1311–1334, 2018.
ista: Nejjar P. 2018. Transition to shocks in TASEP and decoupling of last passage
times. Latin American Journal of Probability and Mathematical Statistics. 15(2),
1311–1334.
mla: Nejjar, Peter. “Transition to Shocks in TASEP and Decoupling of Last Passage
Times.” Latin American Journal of Probability and Mathematical Statistics,
vol. 15, no. 2, Instituto Nacional de Matematica Pura e Aplicada, 2018, pp. 1311–34,
doi:10.30757/ALEA.v15-49.
short: P. Nejjar, Latin American Journal of Probability and Mathematical Statistics
15 (2018) 1311–1334.
date_created: 2018-12-11T11:44:28Z
date_published: 2018-10-01T00:00:00Z
date_updated: 2023-10-10T13:11:29Z
day: '01'
ddc:
- '510'
department:
- _id: LaEr
- _id: JaMa
doi: 10.30757/ALEA.v15-49
ec_funded: 1
external_id:
arxiv:
- '1705.08836'
isi:
- '000460475800022'
file:
- access_level: open_access
checksum: 2ded46aa284a836a8cbb34133a64f1cb
content_type: application/pdf
creator: kschuh
date_created: 2019-02-14T09:44:10Z
date_updated: 2020-07-14T12:47:46Z
file_id: '5981'
file_name: 2018_ALEA_Nejjar.pdf
file_size: 394851
relation: main_file
file_date_updated: 2020-07-14T12:47:46Z
has_accepted_license: '1'
intvolume: ' 15'
isi: 1
issue: '2'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: 1311-1334
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '338804'
name: Random matrices, universality and disordered quantum systems
- _id: 256E75B8-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '716117'
name: Optimal Transport and Stochastic Dynamics
publication: Latin American Journal of Probability and Mathematical Statistics
publication_identifier:
issn:
- 1980-0436
publication_status: published
publisher: Instituto Nacional de Matematica Pura e Aplicada
quality_controlled: '1'
scopus_import: '1'
status: public
title: Transition to shocks in TASEP and decoupling of last passage times
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2018'
...
---
_id: '44'
abstract:
- lang: eng
text: 'Recent realization of a kinetically constrained chain of Rydberg atoms by
Bernien et al., [Nature (London) 551, 579 (2017)] resulted in the observation
of unusual revivals in the many-body quantum dynamics. In our previous work [C.
J. Turner et al., Nat. Phys. 14, 745 (2018)], such dynamics was attributed to
the existence of “quantum scarred” eigenstates in the many-body spectrum of the
experimentally realized model. Here, we present a detailed study of the eigenstate
properties of the same model. We find that the majority of the eigenstates exhibit
anomalous thermalization: the observable expectation values converge to their
Gibbs ensemble values, but parametrically slower compared to the predictions of
the eigenstate thermalization hypothesis (ETH). Amidst the thermalizing spectrum,
we identify nonergodic eigenstates that strongly violate the ETH, whose number
grows polynomially with system size. Previously, the same eigenstates were identified
via large overlaps with certain product states, and were used to explain the revivals
observed in experiment. Here, we find that these eigenstates, in addition to highly
atypical expectation values of local observables, also exhibit subthermal entanglement
entropy that scales logarithmically with the system size. Moreover, we identify
an additional class of quantum scarred eigenstates, and discuss their manifestations
in the dynamics starting from initial product states. We use forward scattering
approximation to describe the structure and physical properties of quantum scarred
eigenstates. Finally, we discuss the stability of quantum scars to various perturbations.
We observe that quantum scars remain robust when the introduced perturbation is
compatible with the forward scattering approximation. In contrast, the perturbations
which most efficiently destroy quantum scars also lead to the restoration of “canonical”
thermalization.'
acknowledged_ssus:
- _id: ScienComp
article_number: '155134'
article_processing_charge: No
author:
- first_name: C J
full_name: Turner, C J
last_name: Turner
- first_name: Alexios
full_name: Michailidis, Alexios
id: 36EBAD38-F248-11E8-B48F-1D18A9856A87
last_name: Michailidis
orcid: 0000-0002-8443-1064
- first_name: D A
full_name: Abanin, D A
last_name: Abanin
- first_name: Maksym
full_name: Serbyn, Maksym
id: 47809E7E-F248-11E8-B48F-1D18A9856A87
last_name: Serbyn
orcid: 0000-0002-2399-5827
- first_name: Z
full_name: Papić, Z
last_name: Papić
citation:
ama: 'Turner CJ, Michailidis A, Abanin DA, Serbyn M, Papić Z. Quantum scarred eigenstates
in a Rydberg atom chain: Entanglement, breakdown of thermalization, and stability
to perturbations. Physical Review B. 2018;98(15). doi:10.1103/PhysRevB.98.155134'
apa: 'Turner, C. J., Michailidis, A., Abanin, D. A., Serbyn, M., & Papić, Z.
(2018). Quantum scarred eigenstates in a Rydberg atom chain: Entanglement, breakdown
of thermalization, and stability to perturbations. Physical Review B. American
Physical Society. https://doi.org/10.1103/PhysRevB.98.155134'
chicago: 'Turner, C J, Alexios Michailidis, D A Abanin, Maksym Serbyn, and Z Papić.
“Quantum Scarred Eigenstates in a Rydberg Atom Chain: Entanglement, Breakdown
of Thermalization, and Stability to Perturbations.” Physical Review B.
American Physical Society, 2018. https://doi.org/10.1103/PhysRevB.98.155134.'
ieee: 'C. J. Turner, A. Michailidis, D. A. Abanin, M. Serbyn, and Z. Papić, “Quantum
scarred eigenstates in a Rydberg atom chain: Entanglement, breakdown of thermalization,
and stability to perturbations,” Physical Review B, vol. 98, no. 15. American
Physical Society, 2018.'
ista: 'Turner CJ, Michailidis A, Abanin DA, Serbyn M, Papić Z. 2018. Quantum scarred
eigenstates in a Rydberg atom chain: Entanglement, breakdown of thermalization,
and stability to perturbations. Physical Review B. 98(15), 155134.'
mla: 'Turner, C. J., et al. “Quantum Scarred Eigenstates in a Rydberg Atom Chain:
Entanglement, Breakdown of Thermalization, and Stability to Perturbations.” Physical
Review B, vol. 98, no. 15, 155134, American Physical Society, 2018, doi:10.1103/PhysRevB.98.155134.'
short: C.J. Turner, A. Michailidis, D.A. Abanin, M. Serbyn, Z. Papić, Physical Review
B 98 (2018).
date_created: 2018-12-11T11:44:19Z
date_published: 2018-10-22T00:00:00Z
date_updated: 2023-10-10T13:28:49Z
day: '22'
department:
- _id: MaSe
doi: 10.1103/PhysRevB.98.155134
external_id:
arxiv:
- '1806.10933'
isi:
- '000447919100001'
intvolume: ' 98'
isi: 1
issue: '15'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1806.10933
month: '10'
oa: 1
oa_version: Preprint
publication: Physical Review B
publication_status: published
publisher: American Physical Society
publist_id: '8010'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Quantum scarred eigenstates in a Rydberg atom chain: Entanglement, breakdown
of thermalization, and stability to perturbations'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 98
year: '2018'
...
---
_id: '328'
abstract:
- lang: eng
text: The drag of turbulent flows can be drastically decreased by adding small amounts
of high molecular weight polymers. While drag reduction initially increases with
polymer concentration, it eventually saturates to what is known as the maximum
drag reduction (MDR) asymptote; this asymptote is generally attributed to the
dynamics being reduced to a marginal yet persistent state of subdued turbulent
motion. Contrary to this accepted view, we show that, for an appropriate choice
of parameters, polymers can reduce the drag beyond the suggested asymptotic limit,
eliminating turbulence and giving way to laminar flow. At higher polymer concentrations,
however, the laminar state becomes unstable, resulting in a fluctuating flow with
the characteristic drag of the MDR asymptote. Our findings indicate that the asymptotic
state is hence dynamically disconnected from ordinary turbulence. © 2018 American
Physical Society.
acknowledged_ssus:
- _id: SSU
acknowledgement: The authors thank Philipp Maier and the IST Austria workshop for
their dedicated technical support.
article_number: '124501'
article_processing_charge: No
author:
- first_name: George H
full_name: Choueiri, George H
id: 448BD5BC-F248-11E8-B48F-1D18A9856A87
last_name: Choueiri
- first_name: Jose M
full_name: Lopez Alonso, Jose M
id: 40770848-F248-11E8-B48F-1D18A9856A87
last_name: Lopez Alonso
orcid: 0000-0002-0384-2022
- first_name: Björn
full_name: Hof, Björn
id: 3A374330-F248-11E8-B48F-1D18A9856A87
last_name: Hof
orcid: 0000-0003-2057-2754
citation:
ama: Choueiri GH, Lopez Alonso JM, Hof B. Exceeding the asymptotic limit of polymer
drag reduction. Physical Review Letters. 2018;120(12). doi:10.1103/PhysRevLett.120.124501
apa: Choueiri, G. H., Lopez Alonso, J. M., & Hof, B. (2018). Exceeding the asymptotic
limit of polymer drag reduction. Physical Review Letters. American Physical
Society. https://doi.org/10.1103/PhysRevLett.120.124501
chicago: Choueiri, George H, Jose M Lopez Alonso, and Björn Hof. “Exceeding the
Asymptotic Limit of Polymer Drag Reduction.” Physical Review Letters. American
Physical Society, 2018. https://doi.org/10.1103/PhysRevLett.120.124501.
ieee: G. H. Choueiri, J. M. Lopez Alonso, and B. Hof, “Exceeding the asymptotic
limit of polymer drag reduction,” Physical Review Letters, vol. 120, no.
12. American Physical Society, 2018.
ista: Choueiri GH, Lopez Alonso JM, Hof B. 2018. Exceeding the asymptotic limit
of polymer drag reduction. Physical Review Letters. 120(12), 124501.
mla: Choueiri, George H., et al. “Exceeding the Asymptotic Limit of Polymer Drag
Reduction.” Physical Review Letters, vol. 120, no. 12, 124501, American
Physical Society, 2018, doi:10.1103/PhysRevLett.120.124501.
short: G.H. Choueiri, J.M. Lopez Alonso, B. Hof, Physical Review Letters 120 (2018).
date_created: 2018-12-11T11:45:51Z
date_published: 2018-03-19T00:00:00Z
date_updated: 2023-10-10T13:27:44Z
day: '19'
department:
- _id: BjHo
doi: 10.1103/PhysRevLett.120.124501
ec_funded: 1
external_id:
isi:
- '000427804000005'
intvolume: ' 120'
isi: 1
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1703.06271
month: '03'
oa: 1
oa_version: Preprint
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '291734'
name: International IST Postdoc Fellowship Programme
- _id: 25152F3A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '306589'
name: Decoding the complexity of turbulence at its origin
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '7537'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Exceeding the asymptotic limit of polymer drag reduction
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 120
year: '2018'
...