[{"file":[{"file_size":742275,"date_updated":"2018-12-12T10:15:29Z","creator":"system","file_name":"IST-2017-802-v1+1_euclid.ejp.1487991681.pdf","date_created":"2018-12-12T10:15:29Z","content_type":"application/pdf","relation":"main_file","access_level":"open_access","file_id":"5149"}],"language":[{"iso":"eng"}],"publication_identifier":{"issn":["10836489"]},"publication_status":"published","volume":22,"license":"https://creativecommons.org/licenses/by/4.0/","oa_version":"Published Version","abstract":[{"text":"We consider products of independent square non-Hermitian random matrices. More precisely, let X1,…, Xn be independent N × N random matrices with independent entries (real or complex with independent real and imaginary parts) with zero mean and variance 1/N. Soshnikov-O’Rourke [19] and Götze-Tikhomirov [15] showed that the empirical spectral distribution of the product of n random matrices with iid entries converges to (equation found). We prove that if the entries of the matrices X1,…, Xn are independent (but not necessarily identically distributed) and satisfy uniform subexponential decay condition, then in the bulk the convergence of the ESD of X1,…, Xn to (0.1) holds up to the scale N–1/2+ε.","lang":"eng"}],"month":"02","intvolume":" 22","scopus_import":"1","ddc":["510"],"date_updated":"2023-09-22T09:27:51Z","department":[{"_id":"LaEr"}],"file_date_updated":"2018-12-12T10:15:29Z","_id":"1023","status":"public","pubrep_id":"802","type":"journal_article","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"day":"06","publication":"Electronic Journal of Probability","has_accepted_license":"1","isi":1,"year":"2017","date_published":"2017-02-06T00:00:00Z","doi":"10.1214/17-EJP38","date_created":"2018-12-11T11:49:44Z","publisher":"Institute of Mathematical Statistics","quality_controlled":"1","oa":1,"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"ista":"Nemish Y. 2017. Local law for the product of independent non-Hermitian random matrices with independent entries. Electronic Journal of Probability. 22, 22.","chicago":"Nemish, Yuriy. “Local Law for the Product of Independent Non-Hermitian Random Matrices with Independent Entries.” Electronic Journal of Probability. Institute of Mathematical Statistics, 2017. https://doi.org/10.1214/17-EJP38.","apa":"Nemish, Y. (2017). Local law for the product of independent non-Hermitian random matrices with independent entries. Electronic Journal of Probability. Institute of Mathematical Statistics. https://doi.org/10.1214/17-EJP38","ama":"Nemish Y. Local law for the product of independent non-Hermitian random matrices with independent entries. Electronic Journal of Probability. 2017;22. doi:10.1214/17-EJP38","ieee":"Y. Nemish, “Local law for the product of independent non-Hermitian random matrices with independent entries,” Electronic Journal of Probability, vol. 22. Institute of Mathematical Statistics, 2017.","short":"Y. Nemish, Electronic Journal of Probability 22 (2017).","mla":"Nemish, Yuriy. “Local Law for the Product of Independent Non-Hermitian Random Matrices with Independent Entries.” Electronic Journal of Probability, vol. 22, 22, Institute of Mathematical Statistics, 2017, doi:10.1214/17-EJP38."},"title":"Local law for the product of independent non-Hermitian random matrices with independent entries","author":[{"first_name":"Yuriy","id":"4D902E6A-F248-11E8-B48F-1D18A9856A87","last_name":"Nemish","orcid":"0000-0002-7327-856X","full_name":"Nemish, Yuriy"}],"publist_id":"6370","external_id":{"isi":["000396611900022"]},"article_processing_charge":"No","article_number":"22"},{"title":"The topology of the cosmic web in terms of persistent Betti numbers","author":[{"last_name":"Pranav","full_name":"Pranav, Pratyush","first_name":"Pratyush"},{"last_name":"Edelsbrunner","full_name":"Edelsbrunner, Herbert","orcid":"0000-0002-9823-6833","id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","first_name":"Herbert"},{"first_name":"Rien","full_name":"Van De Weygaert, Rien","last_name":"Van De Weygaert"},{"last_name":"Vegter","full_name":"Vegter, Gert","first_name":"Gert"},{"first_name":"Michael","full_name":"Kerber, Michael","last_name":"Kerber"},{"last_name":"Jones","full_name":"Jones, Bernard","first_name":"Bernard"},{"first_name":"Mathijs","id":"307CFBC8-F248-11E8-B48F-1D18A9856A87","full_name":"Wintraecken, Mathijs","orcid":"0000-0002-7472-2220","last_name":"Wintraecken"}],"publist_id":"6373","external_id":{"isi":["000395170200039"]},"article_processing_charge":"No","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"ista":"Pranav P, Edelsbrunner H, Van De Weygaert R, Vegter G, Kerber M, Jones B, Wintraecken M. 2017. The topology of the cosmic web in terms of persistent Betti numbers. Monthly Notices of the Royal Astronomical Society. 465(4), 4281–4310.","chicago":"Pranav, Pratyush, Herbert Edelsbrunner, Rien Van De Weygaert, Gert Vegter, Michael Kerber, Bernard Jones, and Mathijs Wintraecken. “The Topology of the Cosmic Web in Terms of Persistent Betti Numbers.” Monthly Notices of the Royal Astronomical Society. Oxford University Press, 2017. https://doi.org/10.1093/mnras/stw2862.","apa":"Pranav, P., Edelsbrunner, H., Van De Weygaert, R., Vegter, G., Kerber, M., Jones, B., & Wintraecken, M. (2017). The topology of the cosmic web in terms of persistent Betti numbers. Monthly Notices of the Royal Astronomical Society. Oxford University Press. https://doi.org/10.1093/mnras/stw2862","ama":"Pranav P, Edelsbrunner H, Van De Weygaert R, et al. The topology of the cosmic web in terms of persistent Betti numbers. Monthly Notices of the Royal Astronomical Society. 2017;465(4):4281-4310. doi:10.1093/mnras/stw2862","ieee":"P. Pranav et al., “The topology of the cosmic web in terms of persistent Betti numbers,” Monthly Notices of the Royal Astronomical Society, vol. 465, no. 4. Oxford University Press, pp. 4281–4310, 2017.","short":"P. Pranav, H. Edelsbrunner, R. Van De Weygaert, G. Vegter, M. Kerber, B. Jones, M. Wintraecken, Monthly Notices of the Royal Astronomical Society 465 (2017) 4281–4310.","mla":"Pranav, Pratyush, et al. “The Topology of the Cosmic Web in Terms of Persistent Betti Numbers.” Monthly Notices of the Royal Astronomical Society, vol. 465, no. 4, Oxford University Press, 2017, pp. 4281–310, doi:10.1093/mnras/stw2862."},"doi":"10.1093/mnras/stw2862","date_published":"2017-01-01T00:00:00Z","date_created":"2018-12-11T11:49:44Z","page":"4281 - 4310","day":"01","publication":"Monthly Notices of the Royal Astronomical Society","isi":1,"year":"2017","quality_controlled":"1","publisher":"Oxford University Press","oa":1,"acknowledgement":"Part of this work has been supported by the 7th Framework Programme for Research of the European Commission, under FETOpen grant number 255827 (CGL Computational Geometry Learning) and ERC advanced grant, URSAT (Understanding Random Systems via Algebraic Topology) number 320422.","department":[{"_id":"HeEd"}],"date_updated":"2023-09-22T09:40:55Z","status":"public","type":"journal_article","_id":"1022","volume":465,"issue":"4","language":[{"iso":"eng"}],"publication_identifier":{"issn":["00358711"]},"publication_status":"published","month":"01","intvolume":" 465","scopus_import":"1","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1608.04519"}],"oa_version":"Submitted Version","abstract":[{"lang":"eng","text":"We introduce a multiscale topological description of the Megaparsec web-like cosmic matter distribution. Betti numbers and topological persistence offer a powerful means of describing the rich connectivity structure of the cosmic web and of its multiscale arrangement of matter and galaxies. Emanating from algebraic topology and Morse theory, Betti numbers and persistence diagrams represent an extension and deepening of the cosmologically familiar topological genus measure and the related geometric Minkowski functionals. In addition to a description of the mathematical background, this study presents the computational procedure for computing Betti numbers and persistence diagrams for density field filtrations. The field may be computed starting from a discrete spatial distribution of galaxies or simulation particles. The main emphasis of this study concerns an extensive and systematic exploration of the imprint of different web-like morphologies and different levels of multiscale clustering in the corresponding computed Betti numbers and persistence diagrams. To this end, we use Voronoi clustering models as templates for a rich variety of web-like configurations and the fractal-like Soneira-Peebles models exemplify a range of multiscale configurations. We have identified the clear imprint of cluster nodes, filaments, walls, and voids in persistence diagrams, along with that of the nested hierarchy of structures in multiscale point distributions. We conclude by outlining the potential of persistent topology for understanding the connectivity structure of the cosmic web, in large simulations of cosmic structure formation and in the challenging context of the observed galaxy distribution in large galaxy surveys."}]},{"oa_version":"None","abstract":[{"text":"The optogenetic revolution enabled spatially-precise and temporally-precise control over protein function, signaling pathway activation, and animal behavior with tremendous success in the dissection of signaling networks and neural circuits. Very recently, optogenetic methods have been paired with optical reporters in novel drug screening platforms. In these all-optical platforms, light remotely activated ion channels and kinases thereby obviating the use of electrophysiology or reagents. Consequences were remarkable operational simplicity, throughput, and cost-effectiveness that culminated in the identification of new drug candidates. These blueprints for all-optical assays also revealed potential pitfalls and inspire all-optical variants of other screens, such as those that aim at better understanding dynamic drug action or orphan protein function.","lang":"eng"}],"intvolume":" 48","month":"12","scopus_import":"1","language":[{"iso":"eng"}],"publication_status":"published","publication_identifier":{"issn":["09581669"]},"ec_funded":1,"volume":48,"_id":"1026","status":"public","article_type":"original","type":"journal_article","date_updated":"2023-09-22T09:26:06Z","department":[{"_id":"HaJa"}],"acknowledgement":"This work was supported by grants of the European Union Seventh Framework Programme (CIG-303564), the Human Frontier Science Program (RGY0084_2012), and the Austrian Science Fund FWF (W1232 MolecularDrugTargets).","quality_controlled":"1","publisher":"Elsevier","publication":"Current Opinion in Biotechnology","day":"01","year":"2017","isi":1,"date_created":"2018-12-11T11:49:45Z","doi":"10.1016/j.copbio.2017.02.006","date_published":"2017-12-01T00:00:00Z","page":"8 - 14","project":[{"name":"In situ real-time imaging of neurotransmitter signaling using designer optical sensors (HFSP Young Investigator)","grant_number":"RGY0084/2012","_id":"255BFFFA-B435-11E9-9278-68D0E5697425"},{"grant_number":"303564","name":"Microbial Ion Channels for Synthetic Neurobiology","call_identifier":"FP7","_id":"25548C20-B435-11E9-9278-68D0E5697425"},{"name":"Molecular Drug Targets","grant_number":"W1232-B24","call_identifier":"FWF","_id":"255A6082-B435-11E9-9278-68D0E5697425"}],"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"ieee":"V. Agus and H. L. Janovjak, “Optogenetic methods in drug screening: Technologies and applications,” Current Opinion in Biotechnology, vol. 48. Elsevier, pp. 8–14, 2017.","short":"V. Agus, H.L. Janovjak, Current Opinion in Biotechnology 48 (2017) 8–14.","apa":"Agus, V., & Janovjak, H. L. (2017). Optogenetic methods in drug screening: Technologies and applications. Current Opinion in Biotechnology. Elsevier. https://doi.org/10.1016/j.copbio.2017.02.006","ama":"Agus V, Janovjak HL. Optogenetic methods in drug screening: Technologies and applications. Current Opinion in Biotechnology. 2017;48:8-14. doi:10.1016/j.copbio.2017.02.006","mla":"Agus, Viviana, and Harald L. Janovjak. “Optogenetic Methods in Drug Screening: Technologies and Applications.” Current Opinion in Biotechnology, vol. 48, Elsevier, 2017, pp. 8–14, doi:10.1016/j.copbio.2017.02.006.","ista":"Agus V, Janovjak HL. 2017. Optogenetic methods in drug screening: Technologies and applications. Current Opinion in Biotechnology. 48, 8–14.","chicago":"Agus, Viviana, and Harald L Janovjak. “Optogenetic Methods in Drug Screening: Technologies and Applications.” Current Opinion in Biotechnology. Elsevier, 2017. https://doi.org/10.1016/j.copbio.2017.02.006."},"title":"Optogenetic methods in drug screening: Technologies and applications","article_processing_charge":"No","external_id":{"isi":["000418313200003"]},"author":[{"first_name":"Viviana","last_name":"Agus","full_name":"Agus, Viviana"},{"orcid":"0000-0002-8023-9315","full_name":"Janovjak, Harald L","last_name":"Janovjak","first_name":"Harald L","id":"33BA6C30-F248-11E8-B48F-1D18A9856A87"}],"publist_id":"6365"},{"date_updated":"2023-09-22T09:40:14Z","department":[{"_id":"JoFi"}],"_id":"1020","type":"journal_article","status":"public","publication_status":"published","publication_identifier":{"issn":["19448244"]},"language":[{"iso":"eng"}],"issue":"9","volume":9,"abstract":[{"lang":"eng","text":"Cellulose is the most abundant biopolymer on Earth. Cellulose fibers, such as the one extracted form cotton or woodpulp, have been used by humankind for hundreds of years to make textiles and paper. Here we show how, by engineering light-matter interaction, we can optimize light scattering using exclusively cellulose nanocrystals. The produced material is sustainable, biocompatible, and when compared to ordinary microfiber-based paper, it shows enhanced scattering strength (×4), yielding a transport mean free path as low as 3.5 μm in the visible light range. The experimental results are in a good agreement with the theoretical predictions obtained with a diffusive model for light propagation."}],"oa_version":"Submitted Version","main_file_link":[{"url":"https://arxiv.org/abs/1702.01415","open_access":"1"}],"scopus_import":"1","intvolume":" 9","month":"03","citation":{"ista":"Caixeiro S, Peruzzo M, Onelli O, Vignolini S, Sapienza R. 2017. Disordered cellulose based nanostructures for enhanced light scattering. ACS Applied Materials and Interfaces. 9(9), 7885–7890.","chicago":"Caixeiro, Soraya, Matilda Peruzzo, Olimpia Onelli, Silvia Vignolini, and Riccardo Sapienza. “Disordered Cellulose Based Nanostructures for Enhanced Light Scattering.” ACS Applied Materials and Interfaces. American Chemical Society, 2017. https://doi.org/10.1021/acsami.6b15986.","ama":"Caixeiro S, Peruzzo M, Onelli O, Vignolini S, Sapienza R. Disordered cellulose based nanostructures for enhanced light scattering. ACS Applied Materials and Interfaces. 2017;9(9):7885-7890. doi:10.1021/acsami.6b15986","apa":"Caixeiro, S., Peruzzo, M., Onelli, O., Vignolini, S., & Sapienza, R. (2017). Disordered cellulose based nanostructures for enhanced light scattering. ACS Applied Materials and Interfaces. American Chemical Society. https://doi.org/10.1021/acsami.6b15986","ieee":"S. Caixeiro, M. Peruzzo, O. Onelli, S. Vignolini, and R. Sapienza, “Disordered cellulose based nanostructures for enhanced light scattering,” ACS Applied Materials and Interfaces, vol. 9, no. 9. American Chemical Society, pp. 7885–7890, 2017.","short":"S. Caixeiro, M. Peruzzo, O. Onelli, S. Vignolini, R. Sapienza, ACS Applied Materials and Interfaces 9 (2017) 7885–7890.","mla":"Caixeiro, Soraya, et al. “Disordered Cellulose Based Nanostructures for Enhanced Light Scattering.” ACS Applied Materials and Interfaces, vol. 9, no. 9, American Chemical Society, 2017, pp. 7885–90, doi:10.1021/acsami.6b15986."},"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","external_id":{"isi":["000396186000002"]},"article_processing_charge":"No","publist_id":"6372","author":[{"first_name":"Soraya","full_name":"Caixeiro, Soraya","last_name":"Caixeiro"},{"last_name":"Peruzzo","full_name":"Peruzzo, Matilda","orcid":"0000-0002-3415-4628","id":"3F920B30-F248-11E8-B48F-1D18A9856A87","first_name":"Matilda"},{"last_name":"Onelli","full_name":"Onelli, Olimpia","first_name":"Olimpia"},{"full_name":"Vignolini, Silvia","last_name":"Vignolini","first_name":"Silvia"},{"first_name":"Riccardo","last_name":"Sapienza","full_name":"Sapienza, Riccardo"}],"title":"Disordered cellulose based nanostructures for enhanced light scattering","year":"2017","isi":1,"publication":"ACS Applied Materials and Interfaces","day":"08","page":"7885 - 7890","date_created":"2018-12-11T11:49:44Z","doi":"10.1021/acsami.6b15986","date_published":"2017-03-08T00:00:00Z","acknowledgement":"This research was funded by the EPSRC (EP/M027961/1), the Leverhulme Trust (RPG-2014-238), Royal Society (RG140457), the BBSRC David Phillips fellowship (BB/K014617/1), and the European Research Council (ERC-2014-STG H2020 639088). All data created during this research are provided in full in the results section and Supporting Information. They are openly available from figshare and can be accessed at ref 30.","oa":1,"publisher":"American Chemical Society","quality_controlled":"1"},{"publication_status":"published","publication_identifier":{"issn":["00221120"]},"language":[{"iso":"eng"}],"volume":817,"abstract":[{"lang":"eng","text":"Most flows in nature and engineering are turbulent because of their large velocities and spatial scales. Laboratory experiments on rotating quasi-Keplerian flows, for which the angular velocity decreases radially but the angular momentum increases, are however laminar at Reynolds numbers exceeding one million. This is in apparent contradiction to direct numerical simulations showing that in these experiments turbulence transition is triggered by the axial boundaries. We here show numerically that as the Reynolds number increases, turbulence becomes progressively confined to the boundary layers and the flow in the bulk fully relaminarizes. Our findings support that turbulence is unlikely to occur in isothermal constant-density quasi-Keplerian flows."}],"oa_version":"Submitted Version","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1608.05527"}],"scopus_import":"1","intvolume":" 817","month":"04","date_updated":"2023-09-22T09:39:46Z","department":[{"_id":"BjHo"}],"_id":"1021","type":"journal_article","status":"public","year":"2017","isi":1,"publication":"Journal of Fluid Mechanics","day":"25","page":"21 - 34","date_created":"2018-12-11T11:49:44Z","doi":"10.1017/jfm.2017.109","date_published":"2017-04-25T00:00:00Z","oa":1,"quality_controlled":"1","publisher":"Cambridge University Press","citation":{"chicago":"Lopez Alonso, Jose M, and Marc Avila. “Boundary Layer Turbulence in Experiments on Quasi Keplerian Flows.” Journal of Fluid Mechanics. Cambridge University Press, 2017. https://doi.org/10.1017/jfm.2017.109.","ista":"Lopez Alonso JM, Avila M. 2017. Boundary layer turbulence in experiments on quasi Keplerian flows. Journal of Fluid Mechanics. 817, 21–34.","mla":"Lopez Alonso, Jose M., and Marc Avila. “Boundary Layer Turbulence in Experiments on Quasi Keplerian Flows.” Journal of Fluid Mechanics, vol. 817, Cambridge University Press, 2017, pp. 21–34, doi:10.1017/jfm.2017.109.","short":"J.M. Lopez Alonso, M. Avila, Journal of Fluid Mechanics 817 (2017) 21–34.","ieee":"J. M. Lopez Alonso and M. Avila, “Boundary layer turbulence in experiments on quasi Keplerian flows,” Journal of Fluid Mechanics, vol. 817. Cambridge University Press, pp. 21–34, 2017.","apa":"Lopez Alonso, J. M., & Avila, M. (2017). Boundary layer turbulence in experiments on quasi Keplerian flows. Journal of Fluid Mechanics. Cambridge University Press. https://doi.org/10.1017/jfm.2017.109","ama":"Lopez Alonso JM, Avila M. Boundary layer turbulence in experiments on quasi Keplerian flows. Journal of Fluid Mechanics. 2017;817:21-34. doi:10.1017/jfm.2017.109"},"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","external_id":{"isi":["000398179100006"]},"article_processing_charge":"No","publist_id":"6371","author":[{"full_name":"Lopez Alonso, Jose M","orcid":"0000-0002-0384-2022","last_name":"Lopez Alonso","first_name":"Jose M","id":"40770848-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Avila, Marc","last_name":"Avila","first_name":"Marc"}],"title":"Boundary layer turbulence in experiments on quasi Keplerian flows","project":[{"_id":"255008E4-B435-11E9-9278-68D0E5697425","name":"Information processing and computation in fish groups","grant_number":"RGP0065/2012"}]},{"quality_controlled":"1","publisher":"Nature Publishing Group","page":"43 - 44","date_created":"2018-12-11T11:49:45Z","date_published":"2017-03-02T00:00:00Z","doi":"10.1038/nature21502","year":"2017","isi":1,"publication":"Nature","day":"02","article_processing_charge":"No","external_id":{"isi":["000395671500025"]},"author":[{"first_name":"Carl-Philipp J","id":"39427864-F248-11E8-B48F-1D18A9856A87","last_name":"Heisenberg","orcid":"0000-0002-0912-4566","full_name":"Heisenberg, Carl-Philipp J"}],"publist_id":"6367","title":"Cell biology: Stretched divisions","citation":{"mla":"Heisenberg, Carl-Philipp J. “Cell Biology: Stretched Divisions.” Nature, vol. 543, no. 7643, Nature Publishing Group, 2017, pp. 43–44, doi:10.1038/nature21502.","apa":"Heisenberg, C.-P. J. (2017). Cell biology: Stretched divisions. Nature. Nature Publishing Group. https://doi.org/10.1038/nature21502","ama":"Heisenberg C-PJ. Cell biology: Stretched divisions. Nature. 2017;543(7643):43-44. doi:10.1038/nature21502","short":"C.-P.J. Heisenberg, Nature 543 (2017) 43–44.","ieee":"C.-P. J. Heisenberg, “Cell biology: Stretched divisions,” Nature, vol. 543, no. 7643. Nature Publishing Group, pp. 43–44, 2017.","chicago":"Heisenberg, Carl-Philipp J. “Cell Biology: Stretched Divisions.” Nature. Nature Publishing Group, 2017. https://doi.org/10.1038/nature21502.","ista":"Heisenberg C-PJ. 2017. Cell biology: Stretched divisions. Nature. 543(7643), 43–44."},"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","scopus_import":"1","intvolume":" 543","month":"03","abstract":[{"text":"Many organ surfaces are covered by a protective epithelial-cell layer. It emerges that such layers are maintained by cell stretching that triggers cell division mediated by the force-sensitive ion-channel protein Piezo1. See Letter p.118","lang":"eng"}],"oa_version":"None","volume":543,"issue":"7643","publication_status":"published","publication_identifier":{"issn":["00280836"]},"language":[{"iso":"eng"}],"type":"journal_article","status":"public","_id":"1025","department":[{"_id":"CaHe"}],"date_updated":"2023-09-22T09:26:59Z"},{"page":"58 - 67","date_created":"2018-12-11T11:49:42Z","date_published":"2017-10-01T00:00:00Z","doi":"10.1016/j.mcn.2017.03.002","year":"2017","isi":1,"has_accepted_license":"1","publication":"Molecular and Cellular Neuroscience","day":"01","oa":1,"publisher":"Academic Press","quality_controlled":"1","article_processing_charge":"No","external_id":{"isi":["000415140700007"]},"author":[{"full_name":"Breuss, Martin","last_name":"Breuss","first_name":"Martin"},{"last_name":"Leca","full_name":"Leca, Ines","first_name":"Ines"},{"first_name":"Thomas","last_name":"Gstrein","full_name":"Gstrein, Thomas"},{"full_name":"Hansen, Andi H","last_name":"Hansen","id":"38853E16-F248-11E8-B48F-1D18A9856A87","first_name":"Andi H"},{"first_name":"David","last_name":"Keays","full_name":"Keays, David"}],"publist_id":"6377","title":"Tubulins and brain development: The origins of functional specification","citation":{"chicago":"Breuss, Martin, Ines Leca, Thomas Gstrein, Andi H Hansen, and David Keays. “Tubulins and Brain Development: The Origins of Functional Specification.” Molecular and Cellular Neuroscience. Academic Press, 2017. https://doi.org/10.1016/j.mcn.2017.03.002.","ista":"Breuss M, Leca I, Gstrein T, Hansen AH, Keays D. 2017. Tubulins and brain development: The origins of functional specification. Molecular and Cellular Neuroscience. 84, 58–67.","mla":"Breuss, Martin, et al. “Tubulins and Brain Development: The Origins of Functional Specification.” Molecular and Cellular Neuroscience, vol. 84, Academic Press, 2017, pp. 58–67, doi:10.1016/j.mcn.2017.03.002.","short":"M. Breuss, I. Leca, T. Gstrein, A.H. Hansen, D. Keays, Molecular and Cellular Neuroscience 84 (2017) 58–67.","ieee":"M. Breuss, I. Leca, T. Gstrein, A. H. Hansen, and D. Keays, “Tubulins and brain development: The origins of functional specification,” Molecular and Cellular Neuroscience, vol. 84. Academic Press, pp. 58–67, 2017.","ama":"Breuss M, Leca I, Gstrein T, Hansen AH, Keays D. Tubulins and brain development: The origins of functional specification. Molecular and Cellular Neuroscience. 2017;84:58-67. doi:10.1016/j.mcn.2017.03.002","apa":"Breuss, M., Leca, I., Gstrein, T., Hansen, A. H., & Keays, D. (2017). Tubulins and brain development: The origins of functional specification. Molecular and Cellular Neuroscience. Academic Press. https://doi.org/10.1016/j.mcn.2017.03.002"},"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","volume":84,"publication_status":"published","publication_identifier":{"issn":["10447431"]},"language":[{"iso":"eng"}],"file":[{"file_size":1436377,"date_updated":"2018-12-12T10:09:19Z","creator":"system","file_name":"IST-2017-806-v1+2_1-s2.0-S1044743116302500-main_1_.pdf","date_created":"2018-12-12T10:09:19Z","content_type":"application/pdf","relation":"main_file","access_level":"open_access","file_id":"4742"}],"scopus_import":"1","intvolume":" 84","month":"10","abstract":[{"lang":"eng","text":"The development of the vertebrate central nervous system is reliant on a complex cascade of biological processes that include mitotic division, relocation of migrating neurons, and the extension of dendritic and axonal processes. Each of these cellular events requires the diverse functional repertoire of the microtubule cytoskeleton for the generation of forces, assembly of macromolecular complexes and transport of molecules and organelles. The tubulins are a multi-gene family that encode for the constituents of microtubules, and have been implicated in a spectrum of neurological disorders. Evidence is building that different tubulins tune the functional properties of the microtubule cytoskeleton dependent on the cell type, developmental profile and subcellular localisation. Here we review of the origins of the functional specification of the tubulin gene family in the developing brain at a transcriptional, translational, and post-transcriptional level. We remind the reader that tubulins are not just loading controls for your average Western blot."}],"oa_version":"Published Version","file_date_updated":"2018-12-12T10:09:19Z","department":[{"_id":"SiHi"}],"date_updated":"2023-09-22T09:42:15Z","ddc":["571"],"tmp":{"short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png"},"type":"journal_article","pubrep_id":"806","status":"public","_id":"1017"},{"_id":"1015","status":"public","pubrep_id":"809","type":"journal_article","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)"},"ddc":["539"],"date_updated":"2023-09-22T09:43:10Z","file_date_updated":"2018-12-12T10:12:32Z","department":[{"_id":"MiLe"}],"oa_version":"Published Version","abstract":[{"lang":"eng","text":"Vortices are commonly observed in the context of classical hydrodynamics: from whirlpools after stirring the coffee in a cup to a violent atmospheric phenomenon such as a tornado, all classical vortices are characterized by an arbitrary circulation value of the local velocity field. On the other hand the appearance of vortices with quantized circulation represents one of the fundamental signatures of macroscopic quantum phenomena. In two-dimensional superfluids quantized vortices play a key role in determining finite-temperature properties, as the superfluid phase and the normal state are separated by a vortex unbinding transition, the Berezinskii-Kosterlitz-Thouless transition. Very recent experiments with two-dimensional superfluid fermions motivate the present work: we present theoretical results based on the renormalization group showing that the universal jump of the superfluid density and the critical temperature crucially depend on the interaction strength, providing a strong benchmark for forthcoming investigations."}],"month":"04","intvolume":" 7","scopus_import":"1","file":[{"file_name":"IST-2017-809-v1+1_srep45702.pdf","date_created":"2018-12-12T10:12:32Z","file_size":478289,"date_updated":"2018-12-12T10:12:32Z","creator":"system","file_id":"4950","content_type":"application/pdf","relation":"main_file","access_level":"open_access"}],"language":[{"iso":"eng"}],"publication_identifier":{"issn":["20452322"]},"publication_status":"published","volume":7,"article_number":"45702","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"ama":"Bighin G, Salasnich L. Vortices and antivortices in two-dimensional ultracold Fermi gases. Scientific Reports. 2017;7. doi:10.1038/srep45702","apa":"Bighin, G., & Salasnich, L. (2017). Vortices and antivortices in two-dimensional ultracold Fermi gases. Scientific Reports. Nature Publishing Group. https://doi.org/10.1038/srep45702","ieee":"G. Bighin and L. Salasnich, “Vortices and antivortices in two-dimensional ultracold Fermi gases,” Scientific Reports, vol. 7. Nature Publishing Group, 2017.","short":"G. Bighin, L. Salasnich, Scientific Reports 7 (2017).","mla":"Bighin, Giacomo, and Luca Salasnich. “Vortices and Antivortices in Two-Dimensional Ultracold Fermi Gases.” Scientific Reports, vol. 7, 45702, Nature Publishing Group, 2017, doi:10.1038/srep45702.","ista":"Bighin G, Salasnich L. 2017. Vortices and antivortices in two-dimensional ultracold Fermi gases. Scientific Reports. 7, 45702.","chicago":"Bighin, Giacomo, and Luca Salasnich. “Vortices and Antivortices in Two-Dimensional Ultracold Fermi Gases.” Scientific Reports. Nature Publishing Group, 2017. https://doi.org/10.1038/srep45702."},"title":"Vortices and antivortices in two-dimensional ultracold Fermi gases","publist_id":"6380","author":[{"first_name":"Giacomo","id":"4CA96FD4-F248-11E8-B48F-1D18A9856A87","last_name":"Bighin","orcid":"0000-0001-8823-9777","full_name":"Bighin, Giacomo"},{"first_name":"Luca","full_name":"Salasnich, Luca","last_name":"Salasnich"}],"external_id":{"isi":["000398148100001"]},"article_processing_charge":"No","quality_controlled":"1","publisher":"Nature Publishing Group","oa":1,"day":"04","publication":"Scientific Reports","isi":1,"has_accepted_license":"1","year":"2017","doi":"10.1038/srep45702","date_published":"2017-04-04T00:00:00Z","date_created":"2018-12-11T11:49:42Z"},{"publication_identifier":{"issn":["09646906"]},"publication_status":"published","language":[{"iso":"eng"}],"volume":26,"issue":"2","abstract":[{"lang":"eng","text":"The integrity and dynamic properties of the microtubule cytoskeleton are indispensable for the development of the mammalian brain. Consequently, mutations in the genes that encode the structural component (the α/β-tubulin heterodimer) can give rise to severe, sporadic neurodevelopmental disorders. These are commonly referred to as the tubulinopathies. Here we report the addition of recessive quadrupedalism, also known as Uner Tan syndrome (UTS), to the growing list of diseases caused by tubulin variants. Analysis of a consanguineous UTS family identified a biallelic TUBB2B mutation, resulting in a p.R390Q amino acid substitution. In addition to the identifying quadrupedal locomotion, all three patients showed severe cerebellar hypoplasia. None, however, displayed the basal ganglia malformations typically associated with TUBB2B mutations. Functional analysis of the R390Q substitution revealed that it did not affect the ability of β-tubulin to fold or become assembled into the α/β-heterodimer, nor did it influence the incorporation of mutant-containing heterodimers into microtubule polymers. The 390Q mutation in S. cerevisiae TUB2 did not affect growth under basal conditions, but did result in increased sensitivity to microtubule-depolymerizing drugs, indicative of a mild impact of this mutation on microtubule function. The TUBB2B mutation described here represents an unusual recessive mode of inheritance for missense-mediated tubulinopathies and reinforces the sensitivity of the developing cerebellum to microtubule defects."}],"oa_version":"None","scopus_import":"1","month":"01","intvolume":" 26","date_updated":"2023-09-22T09:42:42Z","department":[{"_id":"SiHi"}],"_id":"1016","type":"journal_article","status":"public","isi":1,"year":"2017","day":"01","publication":"Human Molecular Genetics","page":"258 - 269","doi":"10.1093/hmg/ddw383","date_published":"2017-01-01T00:00:00Z","date_created":"2018-12-11T11:49:42Z","quality_controlled":"1","publisher":"Oxford University Press","citation":{"ama":"Breuss M, Nguyen T, Srivatsan A, et al. Uner Tan syndrome caused by a homozygous TUBB2B mutation affecting microtubule stability. Human Molecular Genetics. 2017;26(2):258-269. doi:10.1093/hmg/ddw383","apa":"Breuss, M., Nguyen, T., Srivatsan, A., Leca, I., Tian, G., Fritz, T., … Gleeson, J. (2017). Uner Tan syndrome caused by a homozygous TUBB2B mutation affecting microtubule stability. Human Molecular Genetics. Oxford University Press. https://doi.org/10.1093/hmg/ddw383","short":"M. Breuss, T. Nguyen, A. Srivatsan, I. Leca, G. Tian, T. Fritz, A.H. Hansen, D. Musaev, J. Mcevoy Venneri, J. Kiely, R. Rosti, E. Scott, U. Tan, R. Kolodner, N. Cowan, D. Keays, J. Gleeson, Human Molecular Genetics 26 (2017) 258–269.","ieee":"M. Breuss et al., “Uner Tan syndrome caused by a homozygous TUBB2B mutation affecting microtubule stability,” Human Molecular Genetics, vol. 26, no. 2. Oxford University Press, pp. 258–269, 2017.","mla":"Breuss, Martin, et al. “Uner Tan Syndrome Caused by a Homozygous TUBB2B Mutation Affecting Microtubule Stability.” Human Molecular Genetics, vol. 26, no. 2, Oxford University Press, 2017, pp. 258–69, doi:10.1093/hmg/ddw383.","ista":"Breuss M, Nguyen T, Srivatsan A, Leca I, Tian G, Fritz T, Hansen AH, Musaev D, Mcevoy Venneri J, Kiely J, Rosti R, Scott E, Tan U, Kolodner R, Cowan N, Keays D, Gleeson J. 2017. Uner Tan syndrome caused by a homozygous TUBB2B mutation affecting microtubule stability. Human Molecular Genetics. 26(2), 258–269.","chicago":"Breuss, Martin, Thai Nguyen, Anjana Srivatsan, Ines Leca, Guoling Tian, Tanja Fritz, Andi H Hansen, et al. “Uner Tan Syndrome Caused by a Homozygous TUBB2B Mutation Affecting Microtubule Stability.” Human Molecular Genetics. Oxford University Press, 2017. https://doi.org/10.1093/hmg/ddw383."},"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","author":[{"first_name":"Martin","last_name":"Breuss","full_name":"Breuss, Martin"},{"first_name":"Thai","last_name":"Nguyen","full_name":"Nguyen, Thai"},{"first_name":"Anjana","full_name":"Srivatsan, Anjana","last_name":"Srivatsan"},{"first_name":"Ines","full_name":"Leca, Ines","last_name":"Leca"},{"first_name":"Guoling","full_name":"Tian, Guoling","last_name":"Tian"},{"first_name":"Tanja","last_name":"Fritz","full_name":"Fritz, Tanja"},{"full_name":"Hansen, Andi H","last_name":"Hansen","id":"38853E16-F248-11E8-B48F-1D18A9856A87","first_name":"Andi H"},{"full_name":"Musaev, Damir","last_name":"Musaev","first_name":"Damir"},{"last_name":"Mcevoy Venneri","full_name":"Mcevoy Venneri, Jennifer","first_name":"Jennifer"},{"first_name":"James","last_name":"Kiely","full_name":"Kiely, James"},{"first_name":"Rasim","last_name":"Rosti","full_name":"Rosti, Rasim"},{"full_name":"Scott, Eric","last_name":"Scott","first_name":"Eric"},{"full_name":"Tan, Uner","last_name":"Tan","first_name":"Uner"},{"last_name":"Kolodner","full_name":"Kolodner, Richard","first_name":"Richard"},{"first_name":"Nicholas","last_name":"Cowan","full_name":"Cowan, Nicholas"},{"last_name":"Keays","full_name":"Keays, David","first_name":"David"},{"first_name":"Joseph","full_name":"Gleeson, Joseph","last_name":"Gleeson"}],"publist_id":"6379","article_processing_charge":"No","external_id":{"isi":["000397066400002"]},"title":"Uner Tan syndrome caused by a homozygous TUBB2B mutation affecting microtubule stability"},{"date_updated":"2023-09-22T09:41:48Z","department":[{"_id":"EvBe"}],"_id":"1018","type":"journal_article","status":"public","publication_status":"published","language":[{"iso":"eng"}],"volume":174,"issue":"1","abstract":[{"lang":"eng","text":"In plants, the multistep phosphorelay (MSP) pathway mediates a range of regulatory processes, including those activated by cytokinins. The crosstalk between cytokinin response and light is known for a long time. However, the molecular mechanism underlying the interactionbetween light and cytokinin signaling remains elusive. In the screen for upstream regulators we identified a LONG PALE HYPOCOTYL (LPH) gene whose activity is indispensable for spatiotemporally correct expression of CYTOKININ INDEPENDENT-1 (CKI1), encoding the constitutively active sensor histidine kinase that activates MSP signaling. lph is a new allele of HEME OXYGENASE 1 (HY1) which encodes the key protein in the biosynthesis of phytochromobilin, a cofactor of photoconvertiblephytochromes. Our analysis confirmed the light-dependent regulation oftheCKI1 expression pattern. We show that CKI1 expression is under the control of phytochrome A (phyA), functioning as a dual (both positive and negative) regulator of CKI1 expression, presumably via the phyA-regulated transcription factors PHYTOCHROME INTERACTING FACTOR 3 (PIF3) and CIRCADIAN CLOCK ASSOCIATED 1 (CCA1). Changes in CKI1 expression observed in lph/hy1-7 and phy mutants correlatewithmisregulation of MSP signaling, changedcytokinin sensitivity and developmental aberrations,previously shown to be associated with cytokinin and/or CKI1 action. Besides that, we demonstrate novel role of phyA-dependent CKI1 expression in the hypocotyl elongation and hook development during skotomorphogenesis. Based on these results, we propose that the light-dependent regulation of CKI1 provides a plausible mechanistic link underlying the well-known interaction between light- and cytokinin-controlled plant development."}],"oa_version":"None","scopus_import":"1","month":"05","intvolume":" 174","citation":{"mla":"Dobisova, Tereza, et al. “Light Regulated Expression of Sensor Histidine Kinase CKI1 Controls Cytokinin Related Development.” Plant Physiology, vol. 174, no. 1, American Society of Plant Biologists, 2017, pp. 387–404, doi:10.1104/pp.16.01964.","apa":"Dobisova, T., Hrdinova, V., Cuesta, C., Michlickova, S., Urbankova, I., Hejatkova, R., … Hejátko, J. (2017). Light regulated expression of sensor histidine kinase CKI1 controls cytokinin related development. Plant Physiology. American Society of Plant Biologists. https://doi.org/10.1104/pp.16.01964","ama":"Dobisova T, Hrdinova V, Cuesta C, et al. Light regulated expression of sensor histidine kinase CKI1 controls cytokinin related development. Plant Physiology. 2017;174(1):387-404. doi:10.1104/pp.16.01964","short":"T. Dobisova, V. Hrdinova, C. Cuesta, S. Michlickova, I. Urbankova, R. Hejatkova, P. Zadnikova, M. Pernisová, E. Benková, J. Hejátko, Plant Physiology 174 (2017) 387–404.","ieee":"T. Dobisova et al., “Light regulated expression of sensor histidine kinase CKI1 controls cytokinin related development,” Plant Physiology, vol. 174, no. 1. American Society of Plant Biologists, pp. 387–404, 2017.","chicago":"Dobisova, Tereza, Vendula Hrdinova, Candela Cuesta, Sarka Michlickova, Ivana Urbankova, Romana Hejatkova, Petra Zadnikova, Markéta Pernisová, Eva Benková, and Jan Hejátko. “Light Regulated Expression of Sensor Histidine Kinase CKI1 Controls Cytokinin Related Development.” Plant Physiology. American Society of Plant Biologists, 2017. https://doi.org/10.1104/pp.16.01964.","ista":"Dobisova T, Hrdinova V, Cuesta C, Michlickova S, Urbankova I, Hejatkova R, Zadnikova P, Pernisová M, Benková E, Hejátko J. 2017. Light regulated expression of sensor histidine kinase CKI1 controls cytokinin related development. Plant Physiology. 174(1), 387–404."},"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","author":[{"first_name":"Tereza","full_name":"Dobisova, Tereza","last_name":"Dobisova"},{"first_name":"Vendula","last_name":"Hrdinova","full_name":"Hrdinova, Vendula"},{"id":"33A3C818-F248-11E8-B48F-1D18A9856A87","first_name":"Candela","full_name":"Cuesta, Candela","orcid":"0000-0003-1923-2410","last_name":"Cuesta"},{"full_name":"Michlickova, Sarka","last_name":"Michlickova","first_name":"Sarka"},{"full_name":"Urbankova, Ivana","last_name":"Urbankova","first_name":"Ivana"},{"first_name":"Romana","full_name":"Hejatkova, Romana","last_name":"Hejatkova"},{"first_name":"Petra","full_name":"Zadnikova, Petra","last_name":"Zadnikova"},{"full_name":"Pernisová, Markéta","last_name":"Pernisová","first_name":"Markéta"},{"last_name":"Benková","orcid":"0000-0002-8510-9739","full_name":"Benková, Eva","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","first_name":"Eva"},{"first_name":"Jan","full_name":"Hejátko, Jan","last_name":"Hejátko"}],"publist_id":"6375","external_id":{"isi":["000402057200028"]},"article_processing_charge":"No","title":"Light regulated expression of sensor histidine kinase CKI1 controls cytokinin related development","isi":1,"year":"2017","day":"17","publication":"Plant Physiology","page":"387 - 404","doi":"10.1104/pp.16.01964","date_published":"2017-05-17T00:00:00Z","date_created":"2018-12-11T11:49:43Z","quality_controlled":"1","publisher":"American Society of Plant Biologists"}]